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Gene: Vps25 (vacuolar protein sorting 25 homolog) Rattus norvegicus
Symbol: Vps25
Name: vacuolar protein sorting 25 homolog
Description: Predicted to have protein N-terminus binding activity; protein homodimerization activity; and structural molecule activity. Predicted to be involved in negative regulation of epidermal growth factor-activated receptor activity and protein transport to vacuole involved in ubiquitin-dependent protein catabolic process via the multivesicular body sorting pathway. Predicted to localize to ESCRT II complex; cytosol; and nucleus. Orthologous to human VPS25 (vacuolar protein sorting 25 homolog); PARTICIPATES IN endocytosis pathway; INTERACTS WITH acrylamide; ammonium chloride; bisphenol A.
Type: protein-coding
RefSeq Status: VALIDATED
Also known as: ELL-associated protein of 20 kDa; ESCRT-II complex subunit VPS25; LOC681059; similar to Vacuolar protein sorting protein 25 (ELL-associated protein of 20 kDa); vacuolar protein sorting 25; vacuolar protein sorting 25 (S. cerevisiae); vacuolar protein sorting 25 homolog (S. cerevisiae); vacuolar protein-sorting-associated protein 25
Homo sapiens (human) : VPS25 (vacuolar protein sorting 25 homolog)  HGNC  Alliance
Mus musculus (house mouse) : Vps25 (vacuolar protein sorting 25)  MGI  Alliance
Chinchilla lanigera (long-tailed chinchilla) : Vps25 (vacuolar protein sorting 25 homolog)
Pan paniscus (bonobo/pygmy chimpanzee) : VPS25 (vacuolar protein sorting 25 homolog)
Ictidomys tridecemlineatus (thirteen-lined ground squirrel) : Vps25 (vacuolar protein sorting 25 homolog)
Sus scrofa (pig) : VPS25 (vacuolar protein sorting 25 homolog)
Chlorocebus sabaeus (African green monkey) : VPS25 (vacuolar protein sorting 25 homolog)
Heterocephalus glaber (naked mole-rat) : Vps25 (vacuolar protein sorting 25 homolog)
more info ...
Latest Assembly: Rnor_6.0 - RGSC Genome Assembly v6.0
Rat AssemblyChrPosition (strand)SourceGenome Browsers
Rnor_6.01089,174,684 - 89,180,165 (+)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl1089,174,684 - 89,180,160 (+)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.01088,973,180 - 88,978,661 (+)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.41090,277,207 - 90,288,162 (+)NCBIRGSC3.4rn4RGSC3.4
Celera1084,913,038 - 84,918,528 (+)NCBICelera
Cytogenetic Map10q31NCBI
JBrowse: View Region in Genome Browser (JBrowse)

Disease Annotations
Gene-Chemical Interaction Annotations
Gene Ontology Annotations
Molecular Pathway Annotations
References - curated
References - uncurated


Comparative Map Data
Position Markers
QTLs in Region (Rnor_6.0)
miRNA Target Status


RNA-SEQ Expression


Nucleotide Sequences
Protein Sequences

Strain Variation

Strain Sequence Variants (Rnor 6.0)

Additional Information

External Database Links
Nomenclature History
More on Vps25
Alliance Gene
Ensembl Gene
JBrowse: rn5 rn6
NCBI Genome Data Viewer

RGD Object Information
RGD ID: 1584685
Created: 2006-11-19
Species: Rattus norvegicus
Last Modified: 2020-06-09
Status: ACTIVE


RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.