Gene: Asic2 (acid sensing ion channel subunit 2) Rattus norvegicus
Symbol: Asic2
Name: acid sensing ion channel subunit 2
Description: ENCODES a protein that exhibits ion channel activity; voltage-gated sodium channel activity; cation channel activity (ortholog); INVOLVED IN cellular response to acidic pH; cellular response to drug; positive regulation of cation channel activity; ASSOCIATED WITH autistic disorder (ortholog); Inflammation (ortholog); prostate cancer (ortholog); FOUND IN dendritic spine (ortholog); integral component of membrane (ortholog); integral component of plasma membrane (ortholog); INTERACTS WITH (+)-pilocarpine; (RS)-amphetamine; 17alpha-ethynylestradiol
Type: protein-coding
Also known as: Accn1; acid sensing ion channel 2; acid-sensing (proton-gated) ion channel 2; acid-sensing ion channel 2; acid-sensing proton-gated ion channel 2 short variant MDEG2; amiloride-sensitive brain sodium channel 2; amiloride-sensitive cation channel 1; Amiloride-sensitive cation channel 1 neuronal (degenerin); Amiloride-sensitive cation channel 1 neuronal (degenerin) two different splice products: MDEG1 and MDEG2; amiloride-sensitive cation channel 1, neuronal; Amiloride-sensitive cation channel 1, neuronal (degenerin); amiloride-sensitive cation channel neuronal 1; ASIC2a/ASIC2b; BNaC1; BNC1; BNC1k; brain sodium channel 1; degenerin; mammalian degenerin homolog; MDEG; MDEG1; MDEG2
Homo sapiens (human) : ASIC2 (acid sensing ion channel subunit 2)  HGNC  Alliance
Mus musculus (house mouse) : Asic2 (acid-sensing (proton-gated) ion channel 2)  MGI  Alliance
Chinchilla lanigera (long-tailed chinchilla) : Asic2 (acid sensing ion channel subunit 2)
Pan paniscus (bonobo/pygmy chimpanzee) : ASIC2 (acid sensing ion channel subunit 2)
Canis lupus familiaris (dog) : ASIC2 (acid sensing ion channel subunit 2)
Ictidomys tridecemlineatus (thirteen-lined ground squirrel) : Asic2 (acid sensing ion channel subunit 2)
more info ...
Latest Assembly: Rnor_6.0 - RGSC Genome Assembly v6.0
NCBI Annotation Information: Annotation category: suggests misassembly; Annotation category: partial on reference assembly
Rat AssemblyChrPosition (strand)SourceGenome Browsers
Rnor_6.01068,247,800 - 69,347,223 (-)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_5.01067,915,396 - 68,982,618 (-)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.41069,103,244 - 70,190,305 (-)NCBIRGSC3.4rn4RGSC3.4
RGSC_v3.11069,117,480 - 69,386,966 (-)NCBI
Celera1064,828,913 - 65,888,336 (-)NCBICelera
Cytogenetic Map10q26NCBI
JBrowse: View Region in Genome Browser (JBrowse)

Disease Annotations
Gene-Chemical Interaction Annotations
Gene Ontology Annotations
References - curated
References - uncurated
RGD Disease Portals


Comparative Map Data
Position Markers
QTLs in Region (Rnor_6.0)
miRNA Target Status


Nucleotide Sequences
Protein Sequences

Strain Variation

Strain Sequence Variants (Rnor 5.0)

Additional Information

External Database Links
Nomenclature History
More on Asic2
Alliance Gene
Ensembl Gene
JBrowse: rn5 rn6
NCBI Genome Data Viewer

RGD Object Information
RGD ID: 2017
Created: 2000-05-25
Species: Rattus norvegicus
Last Modified: 2018-04-10
Status: ACTIVE