Asic2 (acid sensing ion channel subunit 2) - Rat Genome Database

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Gene: Asic2 (acid sensing ion channel subunit 2) Rattus norvegicus
Analyze
Symbol: Asic2
Name: acid sensing ion channel subunit 2
RGD ID: 2017
Description: Enables voltage-gated sodium channel activity. Involved in cellular response to acidic pH; cellular response to xenobiotic stimulus; and sodium ion transport. Predicted to be located in dendritic spine; neuronal cell body; and plasma membrane. Orthologous to human ASIC2 (acid sensing ion channel subunit 2); INTERACTS WITH (+)-pilocarpine; (+)-schisandrin B; 17alpha-ethynylestradiol.
Type: protein-coding
RefSeq Status: PROVISIONAL
Previously known as: Accn1; acid sensing ion channel 2; acid-sensing (proton-gated) ion channel 2; acid-sensing ion channel 2; acid-sensing proton-gated ion channel 2 short variant MDEG2; amiloride-sensitive brain sodium channel 2; amiloride-sensitive cation channel 1; Amiloride-sensitive cation channel 1 neuronal (degenerin); Amiloride-sensitive cation channel 1 neuronal (degenerin) two different splice products: MDEG1 and MDEG2; amiloride-sensitive cation channel 1, neuronal; Amiloride-sensitive cation channel 1, neuronal (degenerin); amiloride-sensitive cation channel neuronal 1; ASIC2a/ASIC2b; BNaC1; BNC1; BNC1k; brain sodium channel 1; degenerin; mammalian degenerin homolog; MDEG; MDEG1; MDEG2
RGD Orthologs
Human
Mouse
Chinchilla
Bonobo
Dog
Squirrel
Pig
Green Monkey
Naked Mole-Rat
Alliance Genes
More Info more info ...
Latest Assembly: mRatBN7.2 - mRatBN7.2 Assembly
Position:
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr81066,368,308 - 67,438,237 (-)NCBIGRCr8
mRatBN7.21065,870,592 - 66,940,577 (-)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl1065,870,594 - 66,940,424 (-)EnsemblmRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx1070,498,595 - 71,562,027 (-)NCBIRnor_SHRUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.01070,003,921 - 71,067,382 (-)NCBIRnor_SHRSPUTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.01065,464,793 - 66,528,510 (-)NCBIRnor_WKYUTH_Rnor_WKY_Bbb_1.0
Rnor_6.01068,247,800 - 69,347,223 (-)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl1068,248,655 - 68,517,564 (-)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.01067,915,396 - 68,982,618 (-)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.41069,103,244 - 70,190,305 (-)NCBIRGSC3.4RGSC_v3.4rn4RGSC3.4
RGSC_v3.11069,117,480 - 69,386,966 (-)NCBI
Celera1064,828,913 - 65,888,336 (-)NCBICelera
Cytogenetic Map10q26NCBI
JBrowse: View Region in Genome Browser (JBrowse)
Model


Disease Annotations     Click to see Annotation Detail View

Gene Ontology Annotations     Click to see Annotation Detail View

Cellular Component

Molecular Function

References

References - curated
# Reference Title Reference Citation
1. Writing good abstracts: it's a tought job. Carson A Phys Ther 1978 Feb;58(2):175-7.
2. ASIC2b-dependent regulation of ASIC3, an essential acid-sensing ion channel subunit in sensory neurons via the partner protein PICK-1. Deval E, etal., J Biol Chem 2004 May 7;279(19):19531-9. Epub 2004 Feb 19.
3. Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium. Gaudet P, etal., Brief Bioinform. 2011 Sep;12(5):449-62. doi: 10.1093/bib/bbr042. Epub 2011 Aug 27.
4. Rat ISS GO annotations from GOA human gene data--August 2006 GOA data from the GO Consortium
5. Sodium channel expression in hypothalamic osmosensitive neurons in experimental diabetes. Klein JP, etal., Neuroreport 2002 Aug 7;13(11):1481-4.
6. A modulatory subunit of acid sensing ion channels in brain and dorsal root ganglion cells. Lingueglia E, etal., J Biol Chem 1997 Nov 21;272(47):29778-83.
7. Rat ISS GO annotations from MGI mouse gene data--August 2006 MGD data from the GO Consortium
8. Electronic Transfer of LocusLink and RefSeq Data NCBI rat LocusLink and RefSeq merged data July 26, 2002
9. ClinVar Automated Import and Annotation Pipeline RGD automated import pipeline for ClinVar variants, variant-to-disease annotations and gene-to-disease annotations
10. Data Import for Chemical-Gene Interactions RGD automated import pipeline for gene-chemical interactions
11. [Various roentgenomorphological parallels in ulcers of the pyloro-duodenal area] Sokolov IuN, etal., Vestn Rentgenol Radiol 1978 Nov-Dec;(6):3-11.
12. [Clinical consideration with special reference to autopsy cases of malignant tumor in the oral cavity, treated with Bleomycin (author's transl)] Tanaka S, etal., Hiroshima Daigaku Shigaku Zasshi 1975;8(2):168-75.
13. Tentative Sequence Identification Numbers Tentative Sequence Data IDs. TIGR Gene Index, Rat Data
14. Amiloride-insensitive currents of the acid-sensing ion channel-2a (ASIC2a)/ASIC2b heteromeric sour-taste receptor channel. Ugawa S, etal., J Neurosci 2003 May 1;23(9):3616-22.
15. The mammalian degenerin MDEG, an amiloride-sensitive cation channel activated by mutations causing neurodegeneration in Caenorhabditis elegans. Waldmann R, etal., J Biol Chem 1996 May 3;271(18):10433-6.
16. A stomatin-domain protein essential for touch sensation in the mouse. Wetzel C, etal., Nature. 2007 Jan 11;445(7124):206-9. Epub 2006 Dec 13.
Additional References at PubMed
PMID:9360943   PMID:11069180   PMID:11306621   PMID:11457851   PMID:11588175   PMID:11842212   PMID:11854527   PMID:14762118   PMID:14960591   PMID:15381679   PMID:15470133   PMID:15504740  
PMID:15537887   PMID:16085050   PMID:16319075   PMID:17548344   PMID:17936312   PMID:18256271   PMID:18296560   PMID:18310515   PMID:18560896   PMID:19571134   PMID:19590043   PMID:19812697  
PMID:20064394   PMID:20442265   PMID:21566334   PMID:21810271   PMID:22890703   PMID:23239879   PMID:25377529   PMID:25583083   PMID:25744567   PMID:28725010   PMID:29739981   PMID:34215968  
PMID:35447498  


Genomics

Comparative Map Data
Asic2
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr81066,368,308 - 67,438,237 (-)NCBIGRCr8
mRatBN7.21065,870,592 - 66,940,577 (-)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl1065,870,594 - 66,940,424 (-)EnsemblmRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx1070,498,595 - 71,562,027 (-)NCBIRnor_SHRUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.01070,003,921 - 71,067,382 (-)NCBIRnor_SHRSPUTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.01065,464,793 - 66,528,510 (-)NCBIRnor_WKYUTH_Rnor_WKY_Bbb_1.0
Rnor_6.01068,247,800 - 69,347,223 (-)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl1068,248,655 - 68,517,564 (-)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.01067,915,396 - 68,982,618 (-)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.41069,103,244 - 70,190,305 (-)NCBIRGSC3.4RGSC_v3.4rn4RGSC3.4
RGSC_v3.11069,117,480 - 69,386,966 (-)NCBI
Celera1064,828,913 - 65,888,336 (-)NCBICelera
Cytogenetic Map10q26NCBI
ASIC2
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh381733,013,087 - 34,156,768 (-)NCBIGRCh38GRCh38hg38GRCh38
GRCh38.p14 Ensembl1733,013,087 - 34,174,964 (-)EnsemblGRCh38hg38GRCh38
GRCh371731,340,105 - 32,483,787 (-)NCBIGRCh37GRCh37hg19GRCh37
Build 361728,364,218 - 29,507,938 (-)NCBINCBI36Build 36hg18NCBI36
Build 341728,364,220 - 28,644,119NCBI
Celera1728,251,041 - 29,395,277 (-)NCBICelera
Cytogenetic Map17q11.2-q12NCBI
HuRef1728,668,308 - 28,669,144 (-)NCBIHuRef
HuRef1727,525,463 - 27,805,119 (-)NCBIHuRef
CHM1_11731,403,273 - 32,547,482 (-)NCBICHM1_1
T2T-CHM13v2.01733,959,166 - 35,103,157 (-)NCBIT2T-CHM13v2.0
Asic2
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm391180,770,989 - 81,859,222 (-)NCBIGRCm39GRCm39mm39
GRCm39 Ensembl1180,770,995 - 81,859,283 (-)EnsemblGRCm39 Ensembl
GRCm381180,880,163 - 81,968,396 (-)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl1180,880,169 - 81,968,457 (-)EnsemblGRCm38mm10GRCm38
MGSCv371180,693,667 - 81,781,898 (-)NCBIGRCm37MGSCv37mm9NCBIm37
MGSCv361180,696,367 - 80,969,098 (-)NCBIMGSCv36mm8
Celera1190,519,426 - 91,581,630 (-)NCBICelera
Cytogenetic Map11B5NCBI
cM Map1148.43NCBI
Asic2
(Chinchilla lanigera - long-tailed chinchilla)
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0 EnsemblNW_0049554817,850,710 - 8,871,794 (-)EnsemblChiLan1.0
ChiLan1.0NW_0049554817,850,730 - 8,093,255 (-)NCBIChiLan1.0ChiLan1.0
ASIC2
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
NHGRI_mPanPan1-v21930,308,759 - 31,455,007 (+)NCBINHGRI_mPanPan1-v2
NHGRI_mPanPan11733,056,767 - 33,336,170 (+)NCBINHGRI_mPanPan1
Mhudiblu_PPA_v01722,628,322 - 23,774,249 (+)NCBIMhudiblu_PPA_v0Mhudiblu_PPA_v0panPan3
PanPan1.11722,921,267 - 24,066,151 (+)NCBIpanpan1.1PanPan1.1panPan2
ASIC2
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.1939,082,465 - 40,084,612 (+)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
CanFam3.1 Ensembl939,082,806 - 40,083,842 (+)EnsemblCanFam3.1canFam3CanFam3.1
Dog10K_Boxer_Tasha938,308,412 - 39,243,743 (+)NCBIDog10K_Boxer_Tasha
ROS_Cfam_1.0939,899,729 - 40,900,560 (+)NCBIROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl939,900,070 - 40,900,561 (+)EnsemblROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.1938,685,696 - 39,686,492 (+)NCBIUMICH_Zoey_3.1
UNSW_CanFamBas_1.0938,974,406 - 39,980,826 (+)NCBIUNSW_CanFamBas_1.0
UU_Cfam_GSD_1.0939,054,053 - 40,055,731 (+)NCBIUU_Cfam_GSD_1.0
Asic2
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HiC_Itri_2NW_02440560238,060,357 - 39,133,209 (+)NCBIHiC_Itri_2
SpeTri2.0 EnsemblNW_004936538938,752 - 2,011,177 (+)EnsemblSpeTri2.0SpeTri2.0 Ensembl
SpeTri2.0NW_004936538938,266 - 2,011,154 (+)NCBISpeTri2.0SpeTri2.0SpeTri2.0
ASIC2
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 Ensembl1241,727,002 - 42,031,991 (+)EnsemblSscrofa11.1susScr11Sscrofa11.1
Sscrofa11.11241,726,987 - 42,031,997 (+)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
Sscrofa10.21243,445,298 - 43,633,460 (+)NCBISscrofa10.2Sscrofa10.2susScr3
ASIC2
(Chlorocebus sabaeus - green monkey)
Green Monkey AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.11626,547,878 - 27,674,909 (-)NCBIChlSab1.1ChlSab1.1chlSab2
Vero_WHO_p1.0NW_0236660752,347,624 - 3,485,637 (+)NCBIVero_WHO_p1.0Vero_WHO_p1.0
Asic2
(Heterocephalus glaber - naked mole-rat)
Naked Mole-Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla_female_1.0 EnsemblNW_004624875969,626 - 2,049,061 (-)EnsemblHetGla_female_1.0HetGla_female_1.0 EnsemblhetGla2
HetGla 1.0NW_004624875969,857 - 2,049,531 (-)NCBIHetGla_female_1.0HetGla 1.0hetGla2

Variants

.
Variants in Asic2
6067 total Variants
miRNA Target Status

Predicted Target Of
Summary Value
Count of predictions:115
Count of miRNA genes:87
Interacting mature miRNAs:92
Transcripts:ENSRNOT00000009348
Prediction methods:Microtar, Miranda, Rnahybrid, Targetscan
Result types:miRGate_prediction

The detailed report is available here: Full Report CSV TAB Printer

miRNA Target Status data imported from miRGate (http://mirgate.bioinfo.cnio.es/).
For more information about miRGate, see PMID:25858286 or access the full paper here.


QTLs in Region (mRatBN7.2)
The following QTLs overlap with this region.    Full Report CSV TAB Printer Gviewer
RGD IDSymbolNameLODP ValueTraitSub TraitChrStartStopSpecies
70223Bp57Blood pressure QTL 575arterial blood pressure trait (VT:2000000)systolic blood pressure (CMO:0000004)10180676123Rat
8662860Vetf10Vascular elastic tissue fragility QTL 10artery integrity trait (VT:0010639)number of ruptures of the internal elastic lamina of the abdominal aorta and iliac arteries (CMO:0002562)10615418273453136Rat
61427Cia16Collagen induced arthritis QTL 163.2joint integrity trait (VT:0010548)joint inflammation composite score (CMO:0000919)10635789696121100Rat
2303118Mamtr7Mammary tumor resistance QTL 70.003mammary gland integrity trait (VT:0010552)mammary tumor growth rate (CMO:0000344)109658275104670812Rat
2301967Cm73Cardiac mass QTL 734.55heart left ventricle mass (VT:0007031)heart left ventricle weight to body weight ratio (CMO:0000530)101448701189062041Rat
631268Cia21Collagen induced arthritis QTL 213.1joint integrity trait (VT:0010548)joint inflammation composite score (CMO:0000919)1014487011104060283Rat
2316949Gluco60Glucose level QTL 603.7blood glucose amount (VT:0000188)blood glucose level (CMO:0000046)1014487011107057807Rat
1554317Bmd4Bone mineral density QTL 49.40.0001lumbar vertebra mineral mass (VT:0010511)volumetric bone mineral density (CMO:0001553)101981604299406971Rat
724556Pur2Proteinuria QTL 25.5urine protein amount (VT:0005160)urine protein level (CMO:0000591)102242750090627625Rat
61354Pia10Pristane induced arthritis QTL 100.01joint integrity trait (VT:0010548)joint inflammation composite score (CMO:0000919)1023444813104060283Rat
631267Cia20Collagen induced arthritis QTL 203.2joint integrity trait (VT:0010548)joint inflammation composite score (CMO:0000919)1023444813104060283Rat
61325Aia5Adjuvant induced arthritis QTL 50.01joint integrity trait (VT:0010548)joint inflammation composite score (CMO:0000919)1023444813104060283Rat
1298069Bp168Blood pressure QTL 1685.5blood pressure trait (VT:0000183)systolic blood pressure (CMO:0000004)102652195798003205Rat
631542Bp82Blood pressure QTL 826.8arterial blood pressure trait (VT:2000000)systolic blood pressure (CMO:0000004)102652195798952741Rat
2300171Bmd58Bone mineral density QTL 584.90.0001lumbar vertebra mineral mass (VT:0010511)volumetric bone mineral density (CMO:0001553)102694462871944628Rat
10402859Bp381Blood pressure QTL 3810.002arterial blood pressure trait (VT:2000000)mean arterial blood pressure (CMO:0000009)102760646872606468Rat
2292441Bp308Blood pressure QTL 308arterial blood pressure trait (VT:2000000)mean arterial blood pressure (CMO:0000009)102760646872606468Rat
724527Bp148Blood pressure QTL 1480.0001arterial blood pressure trait (VT:2000000)mean arterial blood pressure (CMO:0000009)102845313673453136Rat
1331791Cm31Cardiac mass QTL 313.84606heart mass (VT:0007028)heart wet weight (CMO:0000069)1029299504107211142Rat
631557Bp136Blood pressure QTL 1360.003arterial blood pressure trait (VT:2000000)systolic blood pressure (CMO:0000004)103063205375632053Rat
1576311Pia26Pristane induced arthritis QTL 26joint integrity trait (VT:0010548)joint inflammation composite score (CMO:0000919)103122402675632053Rat
1578779Tcas10Tongue tumor susceptibility QTL 103.12tongue integrity trait (VT:0010553)number of squamous cell tumors of the tongue with diameter greater than 3 mm (CMO:0001950)103129743976297439Rat
1576319Cia29Collagen induced arthritis QTL 29joint integrity trait (VT:0010548)joint inflammation composite score (CMO:0000919)103397392178973921Rat
2317042Aia20Adjuvant induced arthritis QTL 203.38joint integrity trait (VT:0010548)right rear ankle joint diameter (CMO:0002150)103756507982565079Rat
2317043Aia7Adjuvant induced arthritis QTL 73.82joint integrity trait (VT:0010548)left rear ankle joint diameter (CMO:0002149)103756507982565079Rat
1576308Schws1Schwannoma susceptibility QTL 10.0041nervous system integrity trait (VT:0010566)percentage of study population developing trigeminal nerve neurilemmomas during a period of time (CMO:0002017)1040035094102359817Rat
631269Cia22Collagen induced arthritis QTL 228.9joint integrity trait (VT:0010548)joint inflammation composite score (CMO:0000919)1040035094104060283Rat
631270Cia23Collagen induced arthritis QTL 233.9joint integrity trait (VT:0010548)joint inflammation composite score (CMO:0000919)1040035094104060283Rat
631552Vetf2Vascular elastic tissue fragility QTL 24.50.0002aorta elastic tissue integrity trait (VT:0010556)artery internal elastic lamina non-tumorous lesion count (CMO:0001913)104114263386142633Rat
61463Bp12Blood pressure QTL 126.30.0001arterial blood pressure trait (VT:2000000)systolic blood pressure (CMO:0000004)104133325886333258Rat
8552805Bw145Body weight QTL 1452.2body mass (VT:0001259)change in body weight to body weight ratio (CMO:0002216)104194452678307017Rat
1298078Stresp5Stress response QTL 52.990.00025blood corticosterone amount (VT:0005345)plasma corticosterone level (CMO:0001173)1042045676104670812Rat
70188BpQTLcluster1Blood pressure QTL cluster 14.864arterial blood pressure trait (VT:2000000)diastolic blood pressure (CMO:0000005)14232313287323132Rat
70188BpQTLcluster1Blood pressure QTL cluster 14.864arterial blood pressure trait (VT:2000000)systolic blood pressure (CMO:0000004)14232313287323132Rat
70188BpQTLcluster1Blood pressure QTL cluster 14.864arterial blood pressure trait (VT:2000000)mean arterial blood pressure (CMO:0000009)14232313287323132Rat
70188BpQTLcluster1Blood pressure QTL cluster 14.864arterial blood pressure trait (VT:2000000)pulse pressure (CMO:0000292)14232313287323132Rat
70198BpQTLcluster9Blood pressure QTL cluster 92.94arterial blood pressure trait (VT:2000000)mean arterial blood pressure (CMO:0000009)104232313287323132Rat
6893342Cm78Cardiac mass QTL 780.10.88heart mass (VT:0007028)heart weight to body weight ratio (CMO:0000074)104287676679813922Rat
9589030Epfw9Epididymal fat weight QTL 919.240.001epididymal fat pad mass (VT:0010421)epididymal fat pad weight to body weight ratio (CMO:0000658)104444169989441699Rat
7411614Foco18Food consumption QTL 180.001eating behavior trait (VT:0001431)feed conversion ratio (CMO:0001312)104444169989441699Rat
8694173Bw149Body weight QTL 1494.380.001body mass (VT:0001259)body weight gain (CMO:0000420)104444169989441699Rat
2300218Hpcl2Hepatic cholesterol level QTL 2liver cholesterol amount (VT:0010498)liver cholesterol level (CMO:0001597)104502965095600334Rat
631547Bp87Blood pressure QTL 874.5arterial blood pressure trait (VT:2000000)systolic blood pressure (CMO:0000004)104736947092369470Rat
2293705Bmd25Bone mineral density QTL 257.10.0001femur mineral mass (VT:0010011)compact volumetric bone mineral density (CMO:0001730)104944455181709989Rat
7207811Bmd90Bone mineral density QTL 905.2femur size trait (VT:1000369)femoral neck cross-sectional area (CMO:0001697)104944455181709989Rat
2293652Bmd22Bone mineral density QTL 224.90.0001femur mineral mass (VT:0010011)total volumetric bone mineral density (CMO:0001728)104944455181709989Rat
2293669Bmd33Bone mineral density QTL 334.50.0001femur strength trait (VT:0010010)femoral neck polar moment of inertia (CMO:0001670)104944455181709989Rat
2293679Bmd30Bone mineral density QTL 303.50.0001femur mineral mass (VT:0010011)total volumetric bone mineral density (CMO:0001728)104944455181709989Rat
1549846Scl47Serum cholesterol level QTL 473.6blood cholesterol amount (VT:0000180)serum total cholesterol level (CMO:0000363)105057470795574707Rat
70364Bp72Blood pressure QTL 72arterial blood pressure trait (VT:2000000)mean arterial blood pressure (CMO:0000009)105112110096121100Rat
61387Bp1Blood pressure QTL 15.1arterial blood pressure trait (VT:2000000)systolic blood pressure (CMO:0000004)1051770177107211142Rat
61387Bp1Blood pressure QTL 15.1arterial blood pressure trait (VT:2000000)diastolic blood pressure (CMO:0000005)1051770177107211142Rat
1359017Hrtrt21Heart rate QTL 212.4heart pumping trait (VT:2000009)heart rate (CMO:0000002)105177294096772940Rat
631530Tls3T-lymphoma susceptibility QTL 300.0001thymus integrity trait (VT:0010555)percentage of study population developing T-cell lymphomas during a period of time (CMO:0001911)105177461295600334Rat
631535Cm51Cardiac mass QTL 513heart mass (VT:0007028)calculated heart weight (CMO:0000073)105178628291669536Rat
2306787Ean3Experimental allergic neuritis QTL 33.1nervous system integrity trait (VT:0010566)body weight loss (CMO:0001399)105379738566979128Rat
70171Cari1Carrageenan-induced inflammation QTL 14.90.0005hypodermis integrity trait (VT:0010550)inflammatory exudate volume (CMO:0001429)1053797385107211142Rat
70164Bw21Body weight QTL 214.360.00005body mass (VT:0001259)body weight (CMO:0000012)105379749498952626Rat
1354608Cm33Cardiac mass QTL 332.8heart left ventricle mass (VT:0007031)heart left ventricle wet weight (CMO:0000071)105480929299809292Rat
2312662Slep8Serum leptin concentration QTL 80.05blood leptin amount (VT:0005667)serum leptin level (CMO:0000780)1057134272102134272Rat
2312668Scl65Serum cholesterol level QTL 650.001blood cholesterol amount (VT:0000180)serum total cholesterol level (CMO:0000363)1057134272102134272Rat
2312672Insul15Insulin level QTL 150.01blood insulin amount (VT:0001560)serum insulin level (CMO:0000358)1057134272102134272Rat
1549831Bss6Bone structure and strength QTL 64lumbar vertebra strength trait (VT:0010574)vertebra ultimate force (CMO:0001678)1057576521102576521Rat
2293698Bss43Bone structure and strength QTL 435.330.0001lumbar vertebra size trait (VT:0010518)lumbar vertebra cross-sectional area (CMO:0001689)1059209888104209888Rat
1331839Eae18bExperimental allergic encephalomyelitis QTL 18b5.80.03nervous system integrity trait (VT:0010566)experimental autoimmune encephalomyelitis severity score (CMO:0001419)106124830367785171Rat
70363Bp71Blood pressure QTL 710.04arterial blood pressure trait (VT:2000000)mean arterial blood pressure (CMO:0000009)106134527681714865Rat
2306970Anxrr22Anxiety related response QTL 225.95fear/anxiety-related behavior trait (VT:1000241)number of periods of voluntary immobility (CMO:0001045)106134527698211570Rat
6893336Cm75Cardiac mass QTL 750.10.87heart mass (VT:0007028)heart weight to body weight ratio (CMO:0000074)106134527699703528Rat
1558643Cm44Cardiac mass QTL 444.80.0000368heart mass (VT:0007028)heart wet weight (CMO:0000069)106134527699703528Rat
631526Bp76Blood pressure QTL 760.0001arterial blood pressure trait (VT:2000000)systolic blood pressure (CMO:0000004)106134541366743655Rat
61402Niddm3Non-insulin dependent diabetes mellitus QTL 34.58blood glucose amount (VT:0000188)blood glucose level (CMO:0000046)106134541382564856Rat
2313103Bss80Bone structure and strength QTL 8020.0001tibia strength trait (VT:1000284)tibia midshaft endosteal cross-sectional area (CMO:0001716)1062057807107057807Rat
2313105Bss79Bone structure and strength QTL 791.80.0001tibia size trait (VT:0100001)tibia midshaft cross-sectional area (CMO:0001717)1062057807107057807Rat
61449Ciaa2CIA Autoantibody QTL 27.1blood autoantibody amount (VT:0003725)calculated serum anti-type 2 collagen antibody titer (CMO:0001279)1063221094107211142Rat
2298481Eau9Experimental allergic uveoretinitis QTL 90.0169uvea integrity trait (VT:0010551)experimental autoimmune uveitis score (CMO:0001504)106592723382565079Rat
11565453Kidm58Kidney mass QTL 580.002kidney mass (VT:0002707)both kidneys wet weight to body weight ratio (CMO:0000340)106631944767750281Rat
12903252Cm113Cardiac mass QTL 1130.047heart left ventricle mass (VT:0007031)heart left ventricle weight to body weight ratio (CMO:0000530)106631944767750281Rat
12903266Cm114Cardiac mass QTL 1140.02heart right ventricle mass (VT:0007033)heart right ventricle weight to body weight ratio (CMO:0000914)106631944767750281Rat
12903269Am15Aortic mass QTL 150.042aorta mass (VT:0002845)aorta weight to aorta length to body weight ratio (CMO:0002722)106631944767750281Rat
2301405Cm69Cardiac mass QTL 690.031heart mass (VT:0007028)heart wet weight to body weight ratio (CMO:0002408)106631944767750281Rat
12880370Cm105Cardiac mass QTL 1050.008heart mass (VT:0007028)heart wet weight to body weight ratio (CMO:0002408)106631944768164786Rat
12880371Cm106Cardiac mass QTL 1060.007heart left ventricle mass (VT:0007031)heart left ventricle weight to body weight ratio (CMO:0000530)106631944768164786Rat
12880372Am12Aortic mass QTL 120.003aorta mass (VT:0002845)aorta weight to aorta length to body weight ratio (CMO:0002722)106631944768164786Rat
12880375Kidm66Kidney mass QTL 660.009kidney mass (VT:0002707)both kidneys wet weight to body weight ratio (CMO:0000340)106631944768164786Rat
1357344Bp249Blood pressure QTL 2490.0001arterial blood pressure trait (VT:2000000)systolic blood pressure (CMO:0000004)106674365598003205Rat

Markers in Region
D10Rat28  
Rat AssemblyChrPosition (strand)SourceJBrowse
mRatBN7.21066,726,207 - 66,726,496 (+)MAPPERmRatBN7.2
Rnor_6.01069,106,147 - 69,106,433NCBIRnor6.0
Rnor_5.01068,768,516 - 68,768,802UniSTSRnor5.0
RGSC_v3.41069,969,509 - 69,969,738RGDRGSC3.4
RGSC_v3.41069,969,510 - 69,969,738UniSTSRGSC3.4
RGSC_v3.11069,983,132 - 69,983,361RGD
Celera1065,675,340 - 65,675,626UniSTS
SHRSP x BN Map1047.6099UniSTS
SHRSP x BN Map1047.6099RGD
FHH x ACI Map1054.8599RGD
Cytogenetic Map10q26UniSTS
D10Rat123  
Rat AssemblyChrPosition (strand)SourceJBrowse
Rnor_6.01068,824,349 - 68,824,552NCBIRnor6.0
Rnor_5.01068,487,872 - 68,488,075UniSTSRnor5.0
RGSC_v3.41069,683,327 - 69,683,531RGDRGSC3.4
RGSC_v3.41069,683,328 - 69,683,531UniSTSRGSC3.4
RGSC_v3.11069,696,950 - 69,697,154RGD
Celera1065,400,614 - 65,400,817UniSTS
RH 2.0 Map10644.8RGD
FHH x ACI Map1054.7899RGD
Cytogenetic Map10q26UniSTS
D10Rat70  
Rat AssemblyChrPosition (strand)SourceJBrowse
mRatBN7.21066,749,302 - 66,749,441 (+)MAPPERmRatBN7.2
Rnor_6.01069,129,248 - 69,129,386NCBIRnor6.0
Rnor_5.01068,791,952 - 68,792,090UniSTSRnor5.0
Celera1065,698,389 - 65,698,527UniSTS
SHRSP x BN Map1047.6099RGD
SHRSP x BN Map1047.6099UniSTS
FHH x ACI Map1054.8599RGD
Cytogenetic Map10q26UniSTS
D10Rat98  
Rat AssemblyChrPosition (strand)SourceJBrowse
mRatBN7.21066,941,586 - 66,941,813 (+)MAPPERmRatBN7.2
Rnor_6.01069,348,233 - 69,348,459NCBIRnor6.0
Rnor_5.01068,983,628 - 68,983,854UniSTSRnor5.0
RGSC_v3.41070,191,139 - 70,191,595RGDRGSC3.4
RGSC_v3.41070,191,315 - 70,191,541UniSTSRGSC3.4
RGSC_v3.11070,204,762 - 70,205,218RGD
Celera1065,889,346 - 65,889,572UniSTS
RH 2.0 Map10664.3RGD
SHRSP x BN Map1047.6099RGD
FHH x ACI Map1054.8199RGD
Cytogenetic Map10q26UniSTS
D10Arb27  
Rat AssemblyChrPosition (strand)SourceJBrowse
mRatBN7.21065,927,233 - 65,927,370 (+)MAPPERmRatBN7.2
Rnor_6.01068,305,037 - 68,305,173NCBIRnor6.0
Rnor_5.01067,971,352 - 67,971,488UniSTSRnor5.0
RGSC_v3.41069,160,380 - 69,160,517RGDRGSC3.4
RGSC_v3.41069,160,381 - 69,160,517UniSTSRGSC3.4
RGSC_v3.11069,174,003 - 69,174,140RGD
Celera1064,883,710 - 64,883,846UniSTS
SHRSP x BN Map1047.6099UniSTS
SHRSP x BN Map1047.6099RGD
FHH x ACI Map1053.73RGD
Cytogenetic Map10q26UniSTS
D10Rat240  
Rat AssemblyChrPosition (strand)SourceJBrowse
mRatBN7.21066,238,176 - 66,238,315 (+)MAPPERmRatBN7.2
Rnor_6.01068,617,890 - 68,618,026NCBIRnor6.0
Rnor_5.01068,279,697 - 68,279,833UniSTSRnor5.0
RGSC_v3.41069,472,800 - 69,472,938RGDRGSC3.4
RGSC_v3.41069,472,801 - 69,472,937UniSTSRGSC3.4
RGSC_v3.11069,486,423 - 69,486,561RGD
Celera1065,192,998 - 65,193,134UniSTS
SHRSP x BN Map1046.5699RGD
SHRSP x BN Map1046.5699UniSTS
Cytogenetic Map10q26UniSTS
D10Rat210  
Rat AssemblyChrPosition (strand)SourceJBrowse
mRatBN7.21066,824,185 - 66,824,357 (+)MAPPERmRatBN7.2
Rnor_6.01069,230,943 - 69,231,114NCBIRnor6.0
Rnor_6.01069,204,803 - 69,204,972NCBIRnor6.0
Rnor_5.01068,865,323 - 68,865,492UniSTSRnor5.0
RGSC_v3.41070,076,256 - 70,076,428RGDRGSC3.4
RGSC_v3.41070,076,257 - 70,076,428UniSTSRGSC3.4
RGSC_v3.11070,089,765 - 70,090,128RGD
Celera1065,773,858 - 65,774,018UniSTS
SHRSP x BN Map1047.6099UniSTS
SHRSP x BN Map1047.6099RGD
Cytogenetic Map10q26UniSTS
D10Got84  
Rat AssemblyChrPosition (strand)SourceJBrowse
mRatBN7.21066,748,768 - 66,748,890 (+)MAPPERmRatBN7.2
Rnor_6.01069,128,714 - 69,128,835NCBIRnor6.0
Rnor_5.01068,791,418 - 68,791,539UniSTSRnor5.0
RGSC_v3.41069,992,023 - 69,992,145RGDRGSC3.4
RGSC_v3.41069,992,024 - 69,992,145UniSTSRGSC3.4
RGSC_v3.11070,005,646 - 70,005,768RGD
Celera1065,697,827 - 65,697,976UniSTS
RH 2.0 Map10670.0RGD
Cytogenetic Map10q26UniSTS
D10Mco1  
Rat AssemblyChrPosition (strand)SourceJBrowse
mRatBN7.21066,743,655 - 66,743,848 (+)MAPPERmRatBN7.2
Rnor_6.01069,123,603 - 69,123,793NCBIRnor6.0
Rnor_5.01068,786,307 - 68,786,497UniSTSRnor5.0
RGSC_v3.41069,986,912 - 69,987,103RGDRGSC3.4
RGSC_v3.41069,986,913 - 69,987,103UniSTSRGSC3.4
RGSC_v3.11070,000,535 - 70,000,726RGD
Celera1065,692,716 - 65,692,906UniSTS
Cytogenetic Map10q26UniSTS
D10Chm127  
Rat AssemblyChrPosition (strand)SourceJBrowse
mRatBN7.21066,195,534 - 66,195,752 (+)MAPPERmRatBN7.2
Rnor_6.01068,574,049 - 68,574,268NCBIRnor6.0
Rnor_5.01068,236,818 - 68,237,037UniSTSRnor5.0
RGSC_v3.41069,430,368 - 69,430,587UniSTSRGSC3.4
Celera1065,150,775 - 65,150,994UniSTS
Cytogenetic Map10q26UniSTS
D10Chm228  
Rat AssemblyChrPosition (strand)SourceJBrowse
mRatBN7.21066,199,405 - 66,199,644 (+)MAPPERmRatBN7.2
Rnor_6.01068,577,922 - 68,578,160NCBIRnor6.0
Rnor_5.01068,240,691 - 68,240,929UniSTSRnor5.0
RGSC_v3.41069,434,241 - 69,434,479UniSTSRGSC3.4
Celera1065,154,648 - 65,154,872UniSTS
Cytogenetic Map10q26UniSTS
D10Chm229  
Rat AssemblyChrPosition (strand)SourceJBrowse
mRatBN7.21066,319,447 - 66,319,679 (+)MAPPERmRatBN7.2
Rnor_6.01068,697,928 - 68,698,159NCBIRnor6.0
Rnor_5.01068,361,762 - 68,361,993UniSTSRnor5.0
RGSC_v3.41069,555,329 - 69,555,560UniSTSRGSC3.4
Celera1065,274,629 - 65,274,860UniSTS
Cytogenetic Map10q26UniSTS
D10Chm126  
Rat AssemblyChrPosition (strand)SourceJBrowse
mRatBN7.21066,178,300 - 66,178,527 (+)MAPPERmRatBN7.2
Rnor_6.01068,557,469 - 68,557,695NCBIRnor6.0
Rnor_5.01068,220,238 - 68,220,464UniSTSRnor5.0
RGSC_v3.41069,413,265 - 69,413,491UniSTSRGSC3.4
Celera1065,135,453 - 65,135,679UniSTS
Cytogenetic Map10q26UniSTS
D10Chm227  
Rat AssemblyChrPosition (strand)SourceJBrowse
mRatBN7.21065,983,624 - 65,983,799 (+)MAPPERmRatBN7.2
Rnor_6.01068,362,264 - 68,362,438NCBIRnor6.0
Rnor_5.01068,026,935 - 68,027,109UniSTSRnor5.0
RGSC_v3.41069,217,015 - 69,217,189UniSTSRGSC3.4
Celera1064,939,933 - 64,940,107UniSTS
Cytogenetic Map10q26UniSTS
D11Mit68.1  
Rat AssemblyChrPosition (strand)SourceJBrowse
mRatBN7.21066,793,599 - 66,793,737 (+)MAPPERmRatBN7.2
Rnor_6.01069,173,987 - 69,174,124NCBIRnor6.0
Rnor_5.01068,834,861 - 68,834,998UniSTSRnor5.0
RGSC_v3.41070,045,797 - 70,045,934UniSTSRGSC3.4
Celera1065,743,350 - 65,743,487UniSTS
Cytogenetic Map10q26UniSTS
BE108709  
Rat AssemblyChrPosition (strand)SourceJBrowse
mRatBN7.21065,959,436 - 65,959,586 (+)MAPPERmRatBN7.2
Rnor_6.01068,338,076 - 68,338,225NCBIRnor6.0
Rnor_5.01068,002,747 - 68,002,896UniSTSRnor5.0
RGSC_v3.41069,192,827 - 69,192,976UniSTSRGSC3.4
Celera1064,915,745 - 64,915,894UniSTS
Cytogenetic Map10q26UniSTS
D11Bhm136  
Rat AssemblyChrPosition (strand)SourceJBrowse
mRatBN7.21066,793,081 - 66,793,174 (+)MAPPERmRatBN7.2
Rnor_6.01069,173,469 - 69,173,561NCBIRnor6.0
Rnor_5.01068,834,343 - 68,834,435UniSTSRnor5.0
RGSC_v3.41070,045,279 - 70,045,371UniSTSRGSC3.4
Celera1065,742,832 - 65,742,924UniSTS
Cytogenetic Map10q26UniSTS
AU049558  
Rat AssemblyChrPosition (strand)SourceJBrowse
mRatBN7.21066,690,774 - 66,691,066 (+)MAPPERmRatBN7.2
Rnor_6.01069,070,709 - 69,071,000NCBIRnor6.0
Rnor_5.01068,733,078 - 68,733,369UniSTSRnor5.0
RGSC_v3.41069,934,073 - 69,934,364UniSTSRGSC3.4
Celera1065,640,028 - 65,640,319UniSTS
Cytogenetic Map10q26UniSTS
RH143882  
Rat AssemblyChrPosition (strand)SourceJBrowse
mRatBN7.21066,907,563 - 66,907,691 (+)MAPPERmRatBN7.2
Rnor_6.01069,314,218 - 69,314,345NCBIRnor6.0
Rnor_5.01068,950,244 - 68,950,371UniSTSRnor5.0
RGSC_v3.41070,157,636 - 70,157,763UniSTSRGSC3.4
Celera1065,856,057 - 65,856,184UniSTS
Cytogenetic Map10q26UniSTS
BF392929  
Rat AssemblyChrPosition (strand)SourceJBrowse
mRatBN7.21066,432,943 - 66,433,082 (+)MAPPERmRatBN7.2
Rnor_6.01068,812,097 - 68,812,235NCBIRnor6.0
Rnor_5.01068,475,722 - 68,475,860UniSTSRnor5.0
RGSC_v3.41069,669,479 - 69,669,617UniSTSRGSC3.4
Celera1065,388,068 - 65,388,206UniSTS
Cytogenetic Map10q26UniSTS
BE106231  
Rat AssemblyChrPosition (strand)SourceJBrowse
mRatBN7.21066,152,166 - 66,152,386 (+)MAPPERmRatBN7.2
Rnor_6.01068,531,493 - 68,531,712NCBIRnor6.0
Rnor_5.01068,194,262 - 68,194,481UniSTSRnor5.0
RGSC_v3.41069,387,129 - 69,387,348UniSTSRGSC3.4
Celera1065,109,354 - 65,109,573UniSTS
Cytogenetic Map10q26UniSTS
BE108934  
Rat AssemblyChrPosition (strand)SourceJBrowse
mRatBN7.21066,442,990 - 66,443,151 (+)MAPPERmRatBN7.2
Rnor_6.01068,821,535 - 68,821,695NCBIRnor6.0
Rnor_5.01068,485,058 - 68,485,218UniSTSRnor5.0
RGSC_v3.41069,680,514 - 69,680,674UniSTSRGSC3.4
Celera1065,397,800 - 65,397,960UniSTS
Cytogenetic Map10q26UniSTS
AU047274  
Rat AssemblyChrPosition (strand)SourceJBrowse
mRatBN7.21066,620,819 - 66,620,953 (+)MAPPERmRatBN7.2
Rnor_6.01069,000,257 - 69,000,390NCBIRnor6.0
Rnor_5.01068,662,626 - 68,662,759UniSTSRnor5.0
RGSC_v3.41069,864,116 - 69,864,249UniSTSRGSC3.4
Celera1065,570,203 - 65,570,336UniSTS
Cytogenetic Map10q26UniSTS
BE119054  
Rat AssemblyChrPosition (strand)SourceJBrowse
mRatBN7.21066,376,503 - 66,376,705 (+)MAPPERmRatBN7.2
Rnor_6.01068,755,513 - 68,755,714NCBIRnor6.0
Rnor_5.01068,419,468 - 68,419,669UniSTSRnor5.0
RGSC_v3.41069,612,695 - 69,612,896UniSTSRGSC3.4
Celera1065,331,496 - 65,331,697UniSTS
Cytogenetic Map10q26UniSTS
D11Bhm137  
Rat AssemblyChrPosition (strand)SourceJBrowse
mRatBN7.21066,848,595 - 66,848,657 (+)MAPPERmRatBN7.2
Rnor_6.01069,255,251 - 69,255,312NCBIRnor6.0
Rnor_5.01068,891,450 - 68,891,511UniSTSRnor5.0
RGSC_v3.41070,098,879 - 70,098,940UniSTSRGSC3.4
Celera1065,797,173 - 65,797,234UniSTS
Cytogenetic Map10q26UniSTS
AU049121  
Rat AssemblyChrPosition (strand)SourceJBrowse
mRatBN7.21065,982,784 - 65,983,069 (+)MAPPERmRatBN7.2
Rnor_6.01068,361,424 - 68,361,708NCBIRnor6.0
Rnor_5.01068,026,095 - 68,026,379UniSTSRnor5.0
RGSC_v3.41069,216,175 - 69,216,459UniSTSRGSC3.4
Celera1064,939,093 - 64,939,377UniSTS
Cytogenetic Map10q26UniSTS
ha2237  
Rat AssemblyChrPosition (strand)SourceJBrowse
mRatBN7.21066,401,687 - 66,402,215 (+)MAPPERmRatBN7.2
Rnor_6.01068,780,824 - 68,781,351NCBIRnor6.0
Rnor_5.01068,444,449 - 68,444,976UniSTSRnor5.0
RGSC_v3.41069,638,206 - 69,638,733UniSTSRGSC3.4
RGSC_v3.4133,301,972 - 33,302,341UniSTSRGSC3.4
Celera1065,356,806 - 65,357,333UniSTS
Celera134,834,062 - 34,834,431UniSTS
Cytogenetic Map15q25UniSTS
Cytogenetic Map10q26UniSTS
D7Mit271  
Rat AssemblyChrPosition (strand)SourceJBrowse
Celera1065,168,909 - 65,168,960UniSTS
Celera1949,853,183 - 49,853,234UniSTS
Cytogenetic Map10q26UniSTS


Expression


RNA-SEQ Expression
High: > 1000 TPM value   Medium: Between 11 and 1000 TPM
Low: Between 0.5 and 10 TPM   Below Cutoff: < 0.5 TPM

alimentary part of gastrointestinal system circulatory system endocrine system exocrine system hemolymphoid system hepatobiliary system integumental system musculoskeletal system nervous system renal system reproductive system respiratory system appendage
High
Medium 51
Low 3 12 22 14 13 14 23 35 40 1
Below cutoff 28 34 27 5 27 8 11 1 10 8

Sequence


RefSeq Acc Id: ENSRNOT00000086961   ⟹   ENSRNOP00000068763
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.2 Ensembl1065,871,206 - 66,138,379 (-)Ensembl
Rnor_6.0 Ensembl1068,248,655 - 68,517,564 (-)Ensembl
RefSeq Acc Id: ENSRNOT00000112270   ⟹   ENSRNOP00000080191
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.2 Ensembl1065,870,594 - 66,940,424 (-)Ensembl
RefSeq Acc Id: NM_001034014   ⟹   NP_001029186
RefSeq Status: PROVISIONAL
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr81066,368,308 - 67,438,237 (-)NCBI
mRatBN7.21065,870,592 - 66,940,577 (-)NCBI
Rnor_6.01068,247,800 - 69,347,223 (-)NCBI
Rnor_5.01067,915,396 - 68,982,618 (-)NCBI
RGSC_v3.41069,103,244 - 70,190,305 (-)RGD
Celera1064,828,913 - 65,888,336 (-)RGD
Sequence:
RefSeq Acc Id: NM_012892   ⟹   NP_037024
RefSeq Status: PROVISIONAL
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr81066,368,922 - 66,636,061 (-)NCBI
mRatBN7.21065,871,206 - 66,138,379 (-)NCBI
Rnor_6.01068,248,414 - 68,517,579 (-)NCBI
Rnor_5.01067,915,396 - 68,982,618 (-)NCBI
RGSC_v3.41069,103,244 - 70,190,305 (-)RGD
Celera1064,829,527 - 65,095,582 (-)NCBI
Sequence:
RefSeq Acc Id: NP_001029186   ⟸   NM_001034014
- Peptide Label: isoform MDEG1
- UniProtKB: O55163 (UniProtKB/Swiss-Prot),   Q62962 (UniProtKB/Swiss-Prot),   A6HHC7 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: NP_037024   ⟸   NM_012892
- Peptide Label: isoform MDEG2
- UniProtKB: A6HHC8 (UniProtKB/TrEMBL),   A0A0G2JTM0 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: ENSRNOP00000068763   ⟸   ENSRNOT00000086961
RefSeq Acc Id: ENSRNOP00000080191   ⟸   ENSRNOT00000112270

Protein Structures
Name Modeler Protein Id AA Range Protein Structure
AF-Q62962-F1-model_v2 AlphaFold Q62962 1-512 view protein structure

Transcriptome

eQTL   View at Phenogen
WGCNA   View at Phenogen
Tissue/Strain Expression   View at Phenogen

Promoters
RGD ID:13697506
Promoter ID:EPDNEW_R8031
Type:single initiation site
Name:Asic2_1
Description:acid sensing ion channel subunit 2
SO ACC ID:SO:0000170
Source:EPDNEW (Eukaryotic Promoter Database, http://epd.vital-it.ch/)
Experiment Methods:Single-end sequencing.
Position:
Rat AssemblyChrPosition (strand)Source
Rnor_6.01068,517,633 - 68,517,693EPDNEW

Additional Information

Database Acc Id Source(s)
AGR Gene RGD:2017 AgrOrtholog
BioCyc Gene G2FUF-23956 BioCyc
Ensembl Genes ENSRNOG00000058308 Ensembl, ENTREZGENE, UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
Ensembl Transcript ENSRNOT00000086961 ENTREZGENE, UniProtKB/TrEMBL
  ENSRNOT00000086961.2 UniProtKB/Swiss-Prot
  ENSRNOT00000112270 ENTREZGENE
  ENSRNOT00000112270.1 UniProtKB/Swiss-Prot
Gene3D-CATH acid-sensing ion channel 1 domain UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  Acid-sensing ion channel domain UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  Acid-sensing ion channels like domains UniProtKB/TrEMBL
  YojJ-like UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
InterPro ENaC UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  ENaC_chordates UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  ENaC_CS UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
KEGG Report rno:25364 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
NCBI Gene 25364 ENTREZGENE
PANTHER ACID-SENSING ION CHANNEL 2 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  PTHR11690 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
Pfam ASC UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
PhenoGen Asic2 PhenoGen
PRINTS AMINACHANNEL UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
PROSITE ASC UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
RatGTEx ENSRNOG00000058308 RatGTEx
TIGR TC233935
UniProt A0A0G2JTM0 ENTREZGENE, UniProtKB/TrEMBL
  A0A0G3F2N6_RAT UniProtKB/TrEMBL
  A6HHC7 ENTREZGENE, UniProtKB/TrEMBL
  A6HHC8 ENTREZGENE, UniProtKB/TrEMBL
  ASIC2_RAT UniProtKB/Swiss-Prot
  O55163 ENTREZGENE
  Q62962 ENTREZGENE
UniProt Secondary O55163 UniProtKB/Swiss-Prot


Nomenclature History
Date Current Symbol Current Name Previous Symbol Previous Name Description Reference Status
2015-12-23 Asic2  acid sensing ion channel subunit 2  Asic2  acid sensing ion channel 2  Nomenclature updated to reflect human and mouse nomenclature 1299863 APPROVED
2015-12-09 Asic2  acid sensing ion channel 2  Asic2  acid-sensing (proton-gated) ion channel 2  Nomenclature updated to reflect human and mouse nomenclature 1299863 APPROVED
2012-07-13 Asic2  acid-sensing (proton-gated) ion channel 2  Accn1  amiloride-sensitive cation channel 1, neuronal  Nomenclature updated to reflect human and mouse nomenclature 1299863 APPROVED
2008-08-29 Accn1  amiloride-sensitive cation channel 1, neuronal  Accn1  amiloride-sensitive cation channel 1, neuronal (degenerin)  Nomenclature updated to reflect human and mouse nomenclature 1299863 APPROVED
2004-09-10 Accn1  amiloride-sensitive cation channel 1, neuronal (degenerin)    amiloride-sensitive cation channel 1  Name updated 1299863 APPROVED
2002-11-06 Accn1  amiloride-sensitive cation channel 1    Amiloride-sensitive cation channel 1, neuronal (degenerin)  Name updated 625702 APPROVED
2002-06-10 Accn1  Amiloride-sensitive cation channel 1, neuronal (degenerin)      Symbol and Name status set to approved 70586 APPROVED