Eae18b QTL Report (Rattus norvegicus) - Rat Genome Database

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QTL Registration

QTL: Eae18b (Experimental allergic encephalomyelitis QTL 18b) Rattus norvegicus

Symbol: Eae18b
Name: Experimental allergic encephalomyelitis QTL 18b
RGD ID: 1331839
Previously known as: Experimental autoimmune encephalomyelitis QTL 18b; Eae20; Experimental allergic encephalomyelitis QTL 20
Trait: nervous system integrity trait   (VT:0010566)    
Measurement Type: experimental autoimmune encephalomyelitis severity score   (CMO:0001419)    
LOD Score: 5.8
P Value: 0.03
Variance: Not Available
Inheritance Type: recessive
Position
Rat AssemblyChrPosition (strand)SourceJBrowse
mRatBN7.21061,248,303 - 67,785,171RGD_MAPPER_PIPELINEmRatBN7.2
Rnor_6.01064,550,912 - 70,202,084RGD_MAPPER_PIPELINERnor6.0
Rnor_5.01063,463,237 - 70,966,782RGDRnor5.0
RGSC_v3.41067,774,947 - 71,067,824RGDRGSC3.4
RGSC_v3.11067,788,570 - 71,081,447RGD
Cross Type: Intercross
Strains Crossed: DA.ACI-(D10Rat15-D10Rat29) 
JBrowse: View Region in Genome Browser (JBrowse)
Model



Candidate Gene Status
Ccl11 is a candidate Gene for Eae18b
Ccl2 is a candidate Gene for Eae18b
Ccl1 is a candidate Gene for Eae18b

Disease Annotations     Click to see Annotation Detail View

Phenotype Annotations     Click to see Annotation Detail View

Mammalian Phenotype
paralysis  (QTM)
Experimental Data Annotations     Click to see Annotation Detail View

Experimental Condition

Measurement Method

Vertebrate Trait

Rat Strain

References

References - curated
# Reference Title Reference Citation
1. An advanced intercross line resolves Eae18 into two narrow quantitative trait loci syntenic to multiple sclerosis candidate loci. Jagodic M, etal., J Immunol 2004 Jul 15;173(2):1366-73.
2. Genetic variants of CC chemokine genes in experimental autoimmune encephalomyelitis, multiple sclerosis and rheumatoid arthritis. Ockinger J, etal., Genes Immun. 2010 Mar;11(2):142-54. Epub 2009 Oct 29.

Region

Genes in Region
The following Genes overlap with this region.    Full Report CSV TAB Printer Analysis Tools
RGD IDSymbolNameChrStartStopSpecies
68406Timm22translocase of inner mitochondrial membrane 22106125345961261217Rat
1306279AbrABR activator of RhoGEF and GTPase106126251661461331Rat
41243156Trnaa-ugc11transfer RNA alanine (anticodon UGC) 11106130809861308179Rat
41339704LOC120095144uncharacterized LOC120095144106146150261478891Rat
1311234Bhlha9basic helix-loop-helix family, member a9106151360961514730Rat
1307639Trarg1trafficking regulator of GLUT4 (SLC2A4) 1106152110761541494Rat
71093Gosr1golgi SNAP receptor complex member 1106157049961607287Rat
41068944Hmgn1-ps5high mobility group nucleosome binding domain 1, pseudogene 5106158043761594037Rat
2393Cpdcarboxypeptidase D106162352861687491Rat
1587322Rps15-ps10ribosomal protein S15, pseudogene 10106169268061693155Rat
11488308LOC108352222uncharacterized LOC108352222106170324561717561Rat
41115213LOC120095360U6 spliceosomal RNA106170797061708076Rat
1307444Tmigd1transmembrane and immunoglobulin domain containing 1106173907161751025Rat
41381218LOC120095329uncharacterized LOC120095329106175695061760551Rat
1304668Blmhbleomycin hydrolase106177211261815212Rat
3714Slc6a4solute carrier family 6 member 4106182420861858924Rat
1309863Nsrp1nuclear speckle splicing regulatory protein 1106188080761914471Rat
2325359Mir423microRNA 423106191414261914220Rat
1309650Efcab5EF-hand calcium binding domain 5106192641962042745Rat
1309389Ssh2slingshot protein phosphatase 2106205740062309328Rat
708560Coro6coronin 6106231155262319659Rat
1564005Ankrd13bankyrin repeat domain 13B106231966062338342Rat
41092415LOC120095265uncharacterized LOC120095265106233527662340146Rat
69331Git1GIT ArfGAP 1106234208262356379Rat
1559818Tp53i13tumor protein p53 inducible protein 13106235672262363122Rat
1304598Abhd15abhydrolase domain containing 15106236320962368600Rat
708455Taok1TAO kinase 1106237307262465295Rat
41233495LOC120095266cytochrome c oxidase subunit 7C, mitochondrial-like106252904062529853Rat
40941456LOC120095450small nucleolar RNA SNORA17106254858762548718Rat
9158343LOC10369344160S ribosomal protein L27a pseudogene106255924362559753Rat
1596719Nufip2nuclear FMR1 interacting protein 2106257492262607729Rat
2415Cryba1crystallin, beta A1106260837362614726Rat
6502209Bola2-ps5bolA family member 2, pseudogene 5106262745862632944Rat
1562698Myo18amyosin XVIIIa106265421862755465Rat
7573752LOC102557169uncharacterized LOC102557169106273844962740315Rat
1311347Pipoxpipecolic acid and sarcosine oxidase106276987462783484Rat
7519974LOC102551552uncharacterized LOC102551552106278035562783832Rat
619780Sez6seizure related 6 homolog106281893162868686Rat
1305731Phf12PHD finger protein 12106287130962919026Rat
1305508Dhrs13dehydrogenase/reductase 13106292079162925952Rat
70993Flot2flotillin 2106292604762947759Rat
2325428Mir144microRNA 144106296134862961430Rat
2325534Mir451amicroRNA 451a106296152062961591Rat
1304714Eral1Era-like 12S mitochondrial rRNA chaperone 1106296172562968747Rat
1566149Fam222bfamily with sequence similarity 222, member B106298657163052350Rat
1306708Traf4Tnf receptor associated factor 4106305416963060284Rat
1306897Nek8NIMA-related kinase 8106306086863073546Rat
1359195Tlcd1TLC domain containing 1106307446963076502Rat
1304897Rpl23aribosomal protein L23A106307666063079346Rat
41313827Snord42asmall nucleolar RNA, C/D box 42A106307703063077094Rat
40960684Snord4asmall nucleolar RNA, C/D box 4A106307741963077489Rat
41015986Snord42bsmall nucleolar RNA, C/D box 42B106307882563078893Rat
1305058Rab34RAB34, member RAS oncogene family106308331963087538Rat
1561727Proca1protein interacting with cyclin A1106309001863102941Rat
1309290Supt6hSPT6 homolog, histone chaperone and transcription elongation factor106310392063140780Rat
1307274Sdf2stromal cell derived factor 2106314056363151038Rat
1307929Bltp2bridge-like lipid transfer protein family member 2106315599963185213Rat
41054253LOC120095505U6 spliceosomal RNA106318020463180310Rat
41213076LOC120095269uncharacterized LOC120095269106318112363182585Rat
1596488Rskrribosomal protein S6 kinase related106318528663191963Rat
7644068Rpl37a-ps13ribosomal protein L37A, pseudogene 13106319123863195267Rat
620152Spag5sperm associated antigen 5106319871763216746Rat
2091Aldocaldolase, fructose-bisphosphate C106321747763221066Rat
1359436Pigsphosphatidylinositol glycan anchor biosynthesis, class S106322261163237190Rat
3942Unc119unc-119 lipid binding chaperone106323786263243339Rat
3970Foxn1forkhead box N1106325140063273710Rat
41125022Rps2-ps18ribosomal protein S2, pseudogene 18106328210363283054Rat
61920Slc13a2solute carrier family 13 member 2106329181363319127Rat
1309472Slc46a1solute carrier family 46 member 1106336150463367940Rat
1310078Sarm1sterile alpha and TIR motif containing 1106336945663393016Rat
3967Vtnvitronectin106339473263397812Rat
62077SeboxSEBOX homeobox106339921563400086Rat
1566425Tmem199transmembrane protein 199106340249363407065Rat
1307022Poldip2DNA polymerase delta interacting protein 2106340723763417605Rat
3877Tnfaip1TNF alpha induced protein 1106341777463432466Rat
1309400Ift20intraflagellar transport 20106343259763438125Rat
1307423Tmem97transmembrane protein 97106343822863447311Rat
41101894LOC120095392small nucleolar RNA SNORA70106346016863460267Rat
1561602Nlknemo like kinase106346738863590960Rat
1305651Ccnqcyclin Q106364653263647695Rat
41098513Lyrm9l1LYR motif containing 9 like 1106372477063727454Rat
1562012Lyrm9LYR motif containing 9106372571863739772Rat
41332534LOC120095150uncharacterized LOC120095150106377186163781394Rat
1593783Nsmce2-ps2NSE2/MMS21 homolog, SMC5-SMC6 complex SUMO ligase, pseudogene 2106378607563790665Rat
3185Nos2nitric oxide synthase 2106381530863851208Rat
10411933LOC106736471antisense transcript of iNOS gene106385062063851191Rat
3004Lgals5galectin 5106385394963857198Rat
2323679Nos2-ps1nitric oxide synthase 2, pseudogene 1106388755263905593Rat
3005Lgals9galectin 9106390701863930224Rat
1308105Ksr1kinase suppressor of ras 1106396177164098076Rat
1565317Faul2FAU ubiquitin like and ribosomal protein S30 fusion like 2106412475964125452Rat
1307835Wsb1WD repeat and SOCS box-containing 1106420276164219039Rat
41124032LOC120095152uncharacterized LOC120095152106424612364253097Rat
7668412LOC102552371uncharacterized LOC102552371106426819464271560Rat
3168Nf1neurofibromin 1106430602764539112Rat
1359125Omgoligodendrocyte-myelin glycoprotein106446135064464084Rat
6495961Evi2becotropic viral integration site 2B106447269364474311Rat
1593824Evi2aecotropic viral integration site 2A106448576064489660Rat
1305063Rab11fip4RAB11 family interacting protein 4106455010964658123Rat
41184270LOC120095372U6 spliceosomal RNA106455393264554035Rat
40966030LOC120095373U6 spliceosomal RNA106459496064595066Rat
41307510LOC120095366U6 spliceosomal RNA106459891864599020Rat
7592181LOC102550168uncharacterized LOC102550168106466391964665250Rat
11468471Trnat-cgu1transfer RNA threonine (anticodon CGU) 1106466534664665417Rat
4888546Mir193amicroRNA 193a106467234364672454Rat
2325379Mir193microRNA 193106467235464672439Rat
2325371Mir365bmicroRNA 365b106468625564686340Rat
7516121LOC102550051uncharacterized LOC102550051106471663564738279Rat
1587323Stmnl-ps1stathmin like, pseudogene 1106485711864857745Rat
1593257Krt18-ps1keratin 18, pseudogene 1106487762364880512Rat
1311017Utp6UTP6 small subunit processome component106489732164927997Rat
41337556LOC12009527060S ribosomal protein L12-like106494388064944475Rat
9259038Rpl12-ps8ribosomal protein L12, pseudogene 8106495466764955263Rat
1593621Suz12SUZ12 polycomb repressive complex 2 subunit106496703565012916Rat
621517Crlf3cytokine receptor-like factor 3106502422865060746Rat
7655392Rpl12-ps6ribosomal protein L12, pseudogene 6106503209765033557Rat
1561464Atad5ATPase family, AAA domain containing 5106507068265118489Rat
1306595Tefmtranscription elongation factor, mitochondrial106511965765124233Rat
7558326Pgam1-ps3phosphoglycerate mutase 1, pseudogene 3106512448665130349Rat
41337742LOC120095424small nucleolar RNA SNORA43106513290865133055Rat
1586597Nme1-ps3NME/NM23 nucleoside diphosphate kinase 1, pseudogene 3106513688465137365Rat
708487Adap2ArfGAP with dual PH domains 2106513800665166147Rat
41310478Trnaa-cgctransfer RNA alanine (anticodon CGC)106516743865167510Rat
1305252Rnf135ring finger protein 135106517056065189791Rat
1307023Rhot1ras homolog family member T1106519870065262807Rat
1311901Rhbdl3rhomboid like 3106529925065354099Rat
1310429C10h17orf75similar to human chromosome 17 open reading frame 75106536092465373864Rat
2325479Mir632microRNA 632106538575765385834Rat
1308121Zfp207zinc finger protein 207106538580765398086Rat
1306450Psmd11proteasome 26S subunit, non-ATPase 11106543385365479774Rat
11402473Cdk5r1lcyclin-dependent kinase 5 regulatory subunit 1 like106548376565484289Rat
629472Cdk5r1cyclin-dependent kinase 5 regulatory subunit 1106548426665485467Rat
621321Myo1dmyosin ID106548915365765812Rat
41265281LOC120095458small nucleolar RNA SNORA26106563109465631189Rat
1359736Tmem98transmembrane protein 98106579617365807082Rat
1306684Spaca3sperm acrosome associated 3106585061865858090Rat
2017Asic2acid sensing ion channel subunit 2106587059266940577Rat
40986121Rangrf-ps1RAN guanine nucleotide release factor, pseudogene 1106615533966178353Rat
11437457Rpl35al3ribosomal protein L35A like 3106621006366210640Rat
41059526LOC120095274uncharacterized LOC120095274106629879266399056Rat
1560058Phb1-ps1prohibitin 1, pseudogene 1106654646966547373Rat
7489011Mir6327microRNA 6327106659835166598483Rat
40996120Gapdh-ps43Glyceraldehyde-3-phosphate dehydrogenase, pseudogene 43106680369166804868Rat
41188203LOC120095275uncharacterized LOC120095275106689240166906045Rat
11435226LOC108352208uncharacterized LOC108352208106694046266956291Rat
3645Ccl2C-C motif chemokine ligand 2106700542467007222Rat
1359152Ccl7C-C motif chemokine ligand 7106701644667018296Rat
3644Ccl11C-C motif chemokine ligand 11106702832867032929Rat
1309255Ccl12C-C motif chemokine ligand 12106707023067071780Rat
1586495Ccl1C-C motif chemokine ligand 1106712833167131109Rat
1565522Tmem132etransmembrane protein 132E106733086367386790Rat
41176308LOC120095155uncharacterized LOC120095155106750811867610797Rat
1359453Cct6bchaperonin containing TCP1 subunit 6B106765246167701385Rat
11472642LOC108352113transcription factor BTF3 homolog 4 pseudogene106766269967670029Rat
1562573Zfp830zinc finger protein 830106770134067702804Rat
7607868LOC102547954uncharacterized LOC102547954106771659967717654Rat
1309875Lig3DNA ligase 3106771780867741141Rat
727916Rfflring finger and FYVE-like domain containing E3 ubiquitin protein ligase106774071167803669Rat

Markers in Region
The following Markers overlap with this region.    Full Report CSV TAB Printer Gviewer
RGD IDSymbolExpected SizeChrStartStopSpeciesMatch
10141D10Wox15257106322103763221291Ratregion
10142D10Arb9128106322109463221223Ratregion
10995D10Wox24138106381361463813752Ratregion
33846D10Mit2196106364253963642727Ratregion
34445D10Mgh6139106134527661345413Ratregion
34648D10Mgh14114106415546964155584Ratregion
37502D10Rat70127106674930266749441Ratregion
36916D10Rat58170106778500967785171Ratregion
37084D10Rat28244106672620766726496Ratregion
37676D10Rat68227106337737563377570Ratregion
35108D10Rat30158106260203062602196Ratregion
39954D10Rat195224106254189062542101Ratregion
40564D10Rat211153106214541062145556Ratregion
38936D10Rat98235106694158666941813Ratregion
38986D10Rat69214106325120763251419Ratregion
39474D10Rat161173106190123161901410Ratregion
41939D10Arb27125106592723365927370Ratregion
41468D10Rat155174106697895566979128Ratregion
42921D10Rat243222106124830361248527Ratregion
42922D10Rat240131106623817666238315Ratregion
42925D10Rat242144106185230961852455Ratregion
42926D10Rat210160106682418566824357Ratregion
44750D10Got78186106218533062185511Ratregion
44752D10Got80193106445792364458117Ratregion
44758D10Got84125106674876866748890Ratregion
44760D10Got87161106776554667765709Ratregion
625803D10Got82170106476696264767132Ratregion
66409D10Mco42330106381339563813732Ratregion
66491D10Mco61210106481640264816611Ratregion
66522D10Mco72250106443276764433003Ratregion
66552D10Mco1187106674365566743848Ratregion
66717D10Mco16186106412650664126700Ratregion
67320D10Arb17282106415544064155722Ratregion
1578847D10Chm131164106730023567300399Ratregion
1578872D10Chm127220106619553466195752Ratregion
1578899D10Chm228239106619940566199644Ratregion
1578900D10Chm166237106705855267058789Ratregion
1578904D10Chm133208106777683867777046Ratregion
1578907D10Chm129225106719003067190253Ratregion
1578918D10Chm167247106733546567335710Ratregion
1578931D10Chm171232106775004967750281Ratregion
1578948D10Chm132165106778071567780880Ratregion
1578987D10Chm229233106631944766319679Ratregion
1578992D10Chm170224106772021967720443Ratregion
1579009D10Chm125241106578677065787013Ratregion
1579015D10Chm128172106723239867232568Ratregion
1579024D10Chm168230106734292967343161Ratregion
1579039D10Chm169228106740031667400546Ratregion
1579051D10Chm130245106729321667293461Ratregion
1579090D10Chm226245106583287365833120Ratregion
1579129D10Chm126227106617830066178527Ratregion
1579182D10Chm186182106767229167672471Ratregion
1579191D10Chm227175106598362465983799Ratregion
1579193D10Chm165194106700019867000394Ratregion
1639492D10Got406213106513903865139251Ratregion
1642087D10Mco84165106750210867502273Ratregion
1642091D10Mco85345106759592667596271Ratregion
2308866D10Kini1178106702283267023010Ratregion
7205908UniSTS:4934301243106303910863040351Ratregion
7193052D85391134106162359761623731Ratregion
7206434Bhlha9864106151353161514395Ratregion
5038694BE200478109106540534565405454Ratregion
5036143D11Bhm10689106440453964404628Ratregion
5036145D11Bhm13693106679308166793174Ratregion
5036147D11Bhm16374106382850363828577Ratregion
5036151D11Bhm45103106287341562873518Ratregion
5036153D11Bhm6385106350115563501240Ratregion
5036163D11Seg19136106325547963255615Ratregion
5036165D11Seg28131106335964163359772Ratregion
5036167D11Seg36114106342047163420585Ratregion
7206580UniSTS:5471661396106305471663056112Ratregion
5039202RH127571183106324311863243301Ratregion
5036426Nf1141106451907764519218Ratregion
5036486Scya274106700593967006013Ratregion
5036589AU048526192106220238562202577Ratregion
5036899AU049558292106669077466691066Ratregion
5035606STS-H01467131106162006961620200Ratregion
5031338PMC145384P1658106700627067006928Ratregion
5034059RH141206217106162016661620383Ratregion
5034087RH141316204106502378565023989Ratregion
5028891RH142717281106447379464474075Ratregion
5034786AI011333137106334712263347259Ratregion
5034816AI013013115106305067063050785Ratregion
5035040UniSTS:259419436106737739167377827Ratregion
5035042D11Pas33242106764849367648735Ratregion
5035044D11Pas4281106720959967209680Ratregion
5032719RH135050216106340036163400577Ratregion
5027431AW491894130106448666064486790Ratregion
5032899RH136896210106230899862309208Ratregion
5025088BB241108138106325189763252035Ratregion
5033185RH137897163106337087463371037Ratregion
5025272RH127682219106237705662377275Ratregion
5033345RH138491245106181437161814616Ratregion
5028003M23501186106712838467128570Ratregion
5028011M84373189106385081763851006Ratregion
5028011M84373189106385081763851006Ratregion
5028011M84373189106390395463904143Ratregion
5028143D11Mit68.1138106679359966793737Ratregion
5030771AW535144214106538508965385303Ratregion
5030979BE108709150106595943665959586Ratregion
5028527AU042359113106126271961262832Ratregion
5056331RH144317120106158246061582580Ratregion
5051505AW124583147106231966862319815Ratregion
5051507AI847581107106535386565353972Ratregion
5053937RH142937137106497548764975624Ratregion
5054237RH143109258106142301461423271Ratregion
5055243RH143689125106409770964097834Ratregion
5055281RH143711122106260504662605168Ratregion
5059418AW530666161106278359662783757Ratregion
5059418AW530666161106278359662783980Ratregion
5057938BF392929139106643294366433082Ratregion
5057994BF3864170106550292465503081Ratregion
505219122.MMHAP6FLH1.seq153106732978767329940Ratregion
5058068BF386532162106354350563543667Ratregion
5056785RH144579199106209042962090628Ratregion
5052689RH142209188106381307263813260Ratregion
5052709RH142224107106185828361858390Ratregion
5059710BE097677139106183900661839145Ratregion
5055579RH143882128106690756366907691Ratregion
5059886AI072008201106535377365353974Ratregion
5053239RH142534253106507576365076016Ratregion
5058478BE096286154106321927563219514Ratregion
5050230RH133936206106497292364973128Ratregion
5057566AI548110157106292579162925948Ratregion
5050538RH134114220106341680363417022Ratregion
5053575RH142728241106364667463646915Ratregion
5052657RH142190151106162356761623718Ratregion
5052683RH142205160106443299264433152Ratregion
5050406RH134038213106231931662319529Ratregion
5050658RH134183184106374608363746267Ratregion
5051773RH94650101106260839662608498Ratregion
5054735RH143395129106442728264427411Ratregion
5051054RH134412192106157069461570886Ratregion
5041704RH129010220106770364767703867Ratregion
5040914RH128556217106548930265489519Ratregion
5044522RH130652196106385406363854260Ratregion
5044522RH130652196106390714963907345Ratregion
5041418RH128845180106343791163438091Ratregion
5041692RH129003193106315078663150979Ratregion
5046588RH131840201106526246065262661Ratregion
5046204RH131618192106441940464419596Ratregion
5048872RH133154180106310395363104133Ratregion
5048888RH133164219106701797567018193Ratregion
5048986RH133220218106336744863367666Ratregion
5049226RH133358198106774078167740979Ratregion
5047886RH132585211106336662763366838Ratregion
5049136RH133306204106516685665167048Ratregion
5048180RH132754207106162106761621274Ratregion
5048326RH132839161106385097463851135Ratregion
5048326RH132839161106390411163904274Ratregion
5048326RH132839161106390411163904274Ratregion
5042244RH129323219106323692863237147Ratregion
5039798RH127913198106237334262373540Ratregion
5039866RH127952215106774090467741119Ratregion
5039480RH127729184106275522362755407Ratregion
5043426RH130019186106233992162340107Ratregion
5040298RH128203208106305427163054479Ratregion
5042592RH129528219106547949065479709Ratregion
5040444RH128287190106235615862356348Ratregion
5043042RH129795153106308736363087516Ratregion
5072526RH136900160106445676964456929Ratregion
5072618RH136954191106447279464472985Ratregion
5075252RH138487120106294298362943103Ratregion
5075460RH138606230106530139365301621Ratregion
5072364RH136806164106188094161881105Ratregion
5074150RH137850233106275933662759569Ratregion
5074328RH137953181106465438364654564Ratregion
5074340RH137960157106287117562871332Ratregion
5074412RH138002171106512667165126842Ratregion
5076960RH139478201106260556962605770Ratregion
5079370RH140957187106511990165120088Ratregion
5079556RH141066191106340913863409329Ratregion
5079616RH141104207106773900567739212Ratregion
5077278RH139664201106175066361750864Ratregion
5076538RH139234224106441423564414459Ratregion
5080246RH141469190106126019261260382Ratregion
5071084RH134877186106771662267716808Ratregion
5071072RH134870195106700691367007108Ratregion
5073796RH137643128106774191567742043Ratregion
5063392BE107606195106511368065113875Ratregion
5065024BE108934161106644299066443151Ratregion
5067104AU047962237106281969562819932Ratregion
5068224AU047274134106662081966620953Ratregion
5070041RH94434197106453628764536484Ratregion
5068942AU046828244106760878967609035Ratregion
5068950AU046822135106149165461491884Ratregion
5068950AU046822135106149174961491884Ratregion
5070271RH9457196106385073363850828Ratregion
5070271RH9457196106385073363850828Ratregion
5070271RH9457196106390386963903965Ratregion
5070271RH9457196106390386963903965Ratregion
5060056BI279325206106448605964486265Ratregion
5060390BI292081197106574083965741036Ratregion
5065564BE1158930106160561661605772Ratregion
5060828AI145271185106329210963292294Ratregion
5062792AW534454164106267898862679152Ratregion
5064138BI296210219106426827764268496Ratregion
5064168BE120708197106163872061638917Ratregion
5064406BI302108169106445122364451392Ratregion
5061848AW533877166106466458464664750Ratregion
5061964AW527866422106543415965434581Ratregion
5062012BI288141166106208873462088900Ratregion
5062122BE106231220106615216666152386Ratregion
5065468BE109015157106772891767729074Ratregion
5064120AA956238154106339765163397805Ratregion
5060824BE104553152106128760461287756Ratregion
5060930BE104801214106187940761879621Ratregion
5066044BI304152150106159809561598245Ratregion
5063032BF398270195106501048565010680Ratregion
5064684BE108317155106233393262334087Ratregion
5064782BF399703206106227583062276036Ratregion
5061374BI293876150106733889967339049Ratregion
5066438AU048356163106195407361954236Ratregion
5084162AA89381792106301433963014431Ratregion
5084196AI176383220106260120462601439Ratregion
5082257BE119054202106637650366376705Ratregion
5087538PMC30213P1660106548480865485468Ratregion
5082333BI27451095106572392765724022Ratregion
5087763D11Bhm14179106737791067377989Ratregion
5087773D11Seg31318106338355563383873Ratregion
5088092Scya11102106703176367031865Ratregion
5087918Foxn1168106326475863264926Ratregion
5089379AU049121289106598278465983069Ratregion
5089471AU049175280106377807963778360Ratregion
5090811AU049977264106329950263299766Ratregion
5083661BG381406211106310429363104504Ratregion
5084226AA848827181106444372364443904Ratregion
5084682AI170602179106236700262367181Ratregion
5087680Abr166106126255861262725Ratregion
5087759D11Bhm13762106684859566848657Ratregion
5087767D11Bhm84185106391183963912024Ratregion
5087775D11Seg37101106344021663440317Ratregion
5087777RH125886235106774088667741121Ratregion
5088511AU048613259106364243763642696Ratregion
5085072D11Pas27117106750781167507928Ratregion
5085074D11Pas39563106727398667274549Ratregion
5085076D11Pas45157106728274467282901Ratregion
5081060RH141942212106770246567702677Ratregion
5080888RH141841199106216117062161369Ratregion
5083007BF390612185106539598565396170Ratregion
5084782AI172099216106340258863402804Ratregion
5083397BF391060180106448449564484675Ratregion
5081863BE118579183106230784962308032Ratregion
5085754BM383586150106517888465179034Ratregion
5503160ZNF207-1144106539635865397079Ratregion
5503182ksks303396106311016163110557Ratregion
5503178ksks304342106310485763105199Ratregion
5503730GIT1_9564577106235575362356330Ratregion
5504328D17S1484E0106317920663179876Ratregion
5504330D17S1500E189106539622165396985Ratregion
5504833ha22370106640168766402215Ratregion
5505184Lig30106772711467727979Ratregion
5505638UniSTS:4878580106304015363040351Ratregion
5505831Omg239106446175564461994Ratregion
5506483RH71331598106765266367653261Ratregion
5500087UniSTS:236646105106177261061772715Ratregion
5502084MARC_3929-3930:996679185:11066106773352567734591Ratregion
5500085UniSTS:236667204106501244665012650Ratregion
5502337RH124536258106291860762918865Ratregion
5500555RH135952200106500820865008853Ratregion
5500631RH136392235106237702862377263Ratregion
5500394GDB:4340120106262800362628052Ratregion
5500394GDB:4340120106262804962628128Ratregion
5500601RH136114199106340687163407070Ratregion
5501932MARC_17513-17514:1016473117:11431106539381765395248Ratregion
5502024MARC_24051-24052:1030022421:1105106310531263106039Ratregion
5506604CDK5R1_1797832106548462765485459Ratregion
5501806MARC_13669-13670:1002900020:10106291378662914460Ratregion
5502054MARC_26164-26165:1030455897:1760106396924163970001Ratregion
Position Markers

Flank 1: (D10Rat243)
Rat AssemblyChrPosition (strand)Source
mRatBN7.21061,248,303 - 61,248,527 (+)MAPPER
Rnor_6.01064,550,912 - 64,551,135NCBI
Rnor_5.01063,463,237 - 63,463,460UniSTS
RGSC_v3.41067,774,947 - 67,775,171RGD
RGSC_v3.41067,774,948 - 67,775,171UniSTS
RGSC_v3.11067,788,570 - 67,788,794RGD
Celera1060,263,471 - 60,263,702UniSTS
SHRSP x BN Map1045.3799RGD
SHRSP x BN Map1045.3799UniSTS
Cytogenetic Map10q26UniSTS
Peak: (D10Rat123)
Rat AssemblyChrPosition (strand)Source
Rnor_6.01068,824,349 - 68,824,552NCBI
Rnor_5.01068,487,872 - 68,488,075UniSTS
RGSC_v3.41069,683,327 - 69,683,531RGD
RGSC_v3.41069,683,328 - 69,683,531UniSTS
RGSC_v3.11069,696,950 - 69,697,154RGD
Celera1065,400,614 - 65,400,817UniSTS
RH 2.0 Map10644.8RGD
FHH x ACI Map1054.7899RGD
Cytogenetic Map10q26UniSTS
Flank 2: (D10Rat58)
Rat AssemblyChrPosition (strand)Source
mRatBN7.21067,785,009 - 67,785,171 (+)MAPPER
Rnor_6.01070,201,923 - 70,202,084NCBI
Rnor_5.01069,832,628 - 69,832,789UniSTS
Rnor_5.01070,966,621 - 70,966,782UniSTS
RGSC_v3.41071,067,299 - 71,067,824RGD
RGSC_v3.41071,067,496 - 71,067,657UniSTS
RGSC_v3.11071,080,922 - 71,081,447RGD
Celera1066,729,423 - 66,729,584UniSTS
RH 2.0 Map10693.7RGD
FHH x ACI Map1057.0099RGD


QTLs in Region (mRatBN7.2)
The following QTLs overlap with this region.    Full Report CSV TAB Printer Gviewer
RGD IDSymbolNameLODP ValueTraitSub TraitChrStartStopSpecies
61441Btemp1Thermal response to stress QTL 14body temperature trait (VT:0005535)core body temperature (CMO:0001036)103539245763642539Rat
1549846Scl47Serum cholesterol level QTL 473.6blood cholesterol amount (VT:0000180)serum total cholesterol level (CMO:0000363)105057470795574707Rat
1578779Tcas10Tongue tumor susceptibility QTL 103.12tongue integrity trait (VT:0010553)number of squamous cell tumors of the tongue with diameter greater than 3 mm (CMO:0001950)103129743976297439Rat
631565Hcuc4Hepatic copper content QTL 44.15liver copper amount (VT:0003065)liver copper weight to liver dry weight ratio (CMO:0001512)106694181373452992Rat
61449Ciaa2CIA Autoantibody QTL 27.1blood autoantibody amount (VT:0003725)calculated serum anti-type 2 collagen antibody titer (CMO:0001279)1063221094107211142Rat
631552Vetf2Vascular elastic tissue fragility QTL 24.50.0002aorta elastic tissue integrity trait (VT:0010556)artery internal elastic lamina non-tumorous lesion count (CMO:0001913)104114263386142633Rat
631554Bp133Blood pressure QTL 1330.005arterial blood pressure trait (VT:2000000)systolic blood pressure (CMO:0000004)1074336463851208Rat
631557Bp136Blood pressure QTL 1360.003arterial blood pressure trait (VT:2000000)systolic blood pressure (CMO:0000004)103063205375632053Rat
1549831Bss6Bone structure and strength QTL 64lumbar vertebra strength trait (VT:0010574)vertebra ultimate force (CMO:0001678)1057576521102576521Rat
70164Bw21Body weight QTL 214.360.00005body mass (VT:0001259)body weight (CMO:0000012)105379749498952626Rat
61463Bp12Blood pressure QTL 126.30.0001arterial blood pressure trait (VT:2000000)systolic blood pressure (CMO:0000004)104133325886333258Rat
2300218Hpcl2Hepatic cholesterol level QTL 2liver cholesterol amount (VT:0010498)liver cholesterol level (CMO:0001597)104502965095600334Rat
8694173Bw149Body weight QTL 1494.380.001body mass (VT:0001259)body weight gain (CMO:0000420)104444169989441699Rat
70171Cari1Carrageenan-induced inflammation QTL 14.90.0005hypodermis integrity trait (VT:0010550)inflammatory exudate volume (CMO:0001429)1053797385107211142Rat
724527Bp148Blood pressure QTL 1480.0001arterial blood pressure trait (VT:2000000)mean arterial blood pressure (CMO:0000009)102845313673453136Rat
1358897Stresp6Stress response QTL 64.170.022blood norepinephrine amount (VT:0005663)plasma norepinephrine level (CMO:0001010)103539226764155584Rat
1331762Rf40Renal function QTL 403.873kidney blood vessel physiology trait (VT:0100012)absolute change in renal vascular resistance (CMO:0001900)102929950464155584Rat
2300171Bmd58Bone mineral density QTL 584.90.0001lumbar vertebra mineral mass (VT:0010511)volumetric bone mineral density (CMO:0001553)102694462871944628Rat
2301967Cm73Cardiac mass QTL 734.55heart left ventricle mass (VT:0007031)heart left ventricle weight to body weight ratio (CMO:0000530)101448701189062041Rat
70188BpQTLcluster1Blood pressure QTL cluster 14.864arterial blood pressure trait (VT:2000000)pulse pressure (CMO:0000292)14232313287323132Rat
12880372Am12Aortic mass QTL 120.003aorta mass (VT:0002845)aorta weight to aorta length to body weight ratio (CMO:0002722)106631944768164786Rat
12880375Kidm66Kidney mass QTL 660.009kidney mass (VT:0002707)both kidneys wet weight to body weight ratio (CMO:0000340)106631944768164786Rat
1357344Bp249Blood pressure QTL 2490.0001arterial blood pressure trait (VT:2000000)systolic blood pressure (CMO:0000004)106674365598003205Rat
12880370Cm105Cardiac mass QTL 1050.008heart mass (VT:0007028)heart wet weight to body weight ratio (CMO:0002408)106631944768164786Rat
70198BpQTLcluster9Blood pressure QTL cluster 92.94arterial blood pressure trait (VT:2000000)mean arterial blood pressure (CMO:0000009)104232313287323132Rat
12880371Cm106Cardiac mass QTL 1060.007heart left ventricle mass (VT:0007031)heart left ventricle weight to body weight ratio (CMO:0000530)106631944768164786Rat
11565453Kidm58Kidney mass QTL 580.002kidney mass (VT:0002707)both kidneys wet weight to body weight ratio (CMO:0000340)106631944767750281Rat
724556Pur2Proteinuria QTL 25.5urine protein amount (VT:0005160)urine protein level (CMO:0000591)102242750090627625Rat
70223Bp57Blood pressure QTL 575arterial blood pressure trait (VT:2000000)systolic blood pressure (CMO:0000004)10180676123Rat
70224Eae3Experimental allergic encephalomyelitis QTL 34.1nervous system integrity trait (VT:0010566)experimental autoimmune encephalomyelitis incidence/prevalence measurement (CMO:0001046)102652195761345413Rat
2298481Eau9Experimental allergic uveoretinitis QTL 90.0169uvea integrity trait (VT:0010551)experimental autoimmune uveitis score (CMO:0001504)106592723382565079Rat
1331791Cm31Cardiac mass QTL 313.84606heart mass (VT:0007028)heart wet weight (CMO:0000069)1029299504107211142Rat
2313087Bmd80Bone mineral density QTL 803.20.0001tibia mineral mass (VT:1000283)total volumetric bone mineral density (CMO:0001728)101960648364606483Rat
2289985Bp305Blood pressure QTL 305arterial blood pressure trait (VT:2000000)systolic blood pressure (CMO:0000004)106750210873579767Rat
1354608Cm33Cardiac mass QTL 332.8heart left ventricle mass (VT:0007031)heart left ventricle wet weight (CMO:0000071)105480929299809292Rat
1558643Cm44Cardiac mass QTL 444.80.0000368heart mass (VT:0007028)heart wet weight (CMO:0000069)106134527699703528Rat
1576319Cia29Collagen induced arthritis QTL 29joint integrity trait (VT:0010548)joint inflammation composite score (CMO:0000919)103397392178973921Rat
1331839Eae18bExperimental allergic encephalomyelitis QTL 18b5.80.03nervous system integrity trait (VT:0010566)experimental autoimmune encephalomyelitis severity score (CMO:0001419)106124830367785171Rat
1576308Schws1Schwannoma susceptibility QTL 10.0041nervous system integrity trait (VT:0010566)percentage of study population developing trigeminal nerve neurilemmomas during a period of time (CMO:0002017)1040035094102359817Rat
1576311Pia26Pristane induced arthritis QTL 26joint integrity trait (VT:0010548)joint inflammation composite score (CMO:0000919)103122402675632053Rat
6893336Cm75Cardiac mass QTL 750.10.87heart mass (VT:0007028)heart weight to body weight ratio (CMO:0000074)106134527699703528Rat
6893342Cm78Cardiac mass QTL 780.10.88heart mass (VT:0007028)heart weight to body weight ratio (CMO:0000074)104287676679813922Rat
2313055Bw96Body weight QTL 963.60.0001body mass (VT:0001259)body weight (CMO:0000012)101960648364606483Rat
1298069Bp168Blood pressure QTL 1685.5blood pressure trait (VT:0000183)systolic blood pressure (CMO:0000004)102652195798003205Rat
8657410Bp374Blood pressure QTL 374heart left ventricle size trait (VT:0002753)heart left ventricle end-diastolic diameter (CMO:0000982)106697895567750281Rat
2293669Bmd33Bone mineral density QTL 334.50.0001femur strength trait (VT:0010010)femoral neck polar moment of inertia (CMO:0001670)104944455181709989Rat
61325Aia5Adjuvant induced arthritis QTL 50.01joint integrity trait (VT:0010548)joint inflammation composite score (CMO:0000919)1023444813104060283Rat
1298078Stresp5Stress response QTL 52.990.00025blood corticosterone amount (VT:0005345)plasma corticosterone level (CMO:0001173)1042045676104670812Rat
2293679Bmd30Bone mineral density QTL 303.50.0001femur mineral mass (VT:0010011)total volumetric bone mineral density (CMO:0001728)104944455181709989Rat
12903252Cm113Cardiac mass QTL 1130.047heart left ventricle mass (VT:0007031)heart left ventricle weight to body weight ratio (CMO:0000530)106631944767750281Rat
2298544Neuinf9Neuroinflammation QTL 94.6nervous system integrity trait (VT:0010566)spinal cord complement component 1, q subcomponent, B chain mRNA level (CMO:0002126)10580199062146030Rat
1579917Bp282Blood pressure QTL 2820.001arterial blood pressure trait (VT:2000000)mean arterial blood pressure (CMO:0000009)106740031668164786Rat
1554317Bmd4Bone mineral density QTL 49.40.0001lumbar vertebra mineral mass (VT:0010511)volumetric bone mineral density (CMO:0001553)101981604299406971Rat
1598852Anxrr19Anxiety related response QTL 195.07body movement coordination trait (VT:0005424)number of rearing movements in an experimental apparatus (CMO:0001752)101816784163167841Rat
1581497Esta1Estrogen-induced thymic atrophy QTL 1thymus mass (VT:0004954)thymus wet weight (CMO:0000855)102132980561345413Rat
12903269Am15Aortic mass QTL 150.042aorta mass (VT:0002845)aorta weight to aorta length to body weight ratio (CMO:0002722)106631944767750281Rat
12903266Cm114Cardiac mass QTL 1140.02heart right ventricle mass (VT:0007033)heart right ventricle weight to body weight ratio (CMO:0000914)106631944767750281Rat
61354Pia10Pristane induced arthritis QTL 100.01joint integrity trait (VT:0010548)joint inflammation composite score (CMO:0000919)1023444813104060283Rat
2313103Bss80Bone structure and strength QTL 8020.0001tibia strength trait (VT:1000284)tibia midshaft endosteal cross-sectional area (CMO:0001716)1062057807107057807Rat
2303118Mamtr7Mammary tumor resistance QTL 70.003mammary gland integrity trait (VT:0010552)mammary tumor growth rate (CMO:0000344)109658275104670812Rat
2313105Bss79Bone structure and strength QTL 791.80.0001tibia size trait (VT:0100001)tibia midshaft cross-sectional area (CMO:0001717)1062057807107057807Rat
9589030Epfw9Epididymal fat weight QTL 919.240.001epididymal fat pad mass (VT:0010421)epididymal fat pad weight to body weight ratio (CMO:0000658)104444169989441699Rat
10402859Bp381Blood pressure QTL 3810.002arterial blood pressure trait (VT:2000000)mean arterial blood pressure (CMO:0000009)102760646872606468Rat
2293652Bmd22Bone mineral density QTL 224.90.0001femur mineral mass (VT:0010011)total volumetric bone mineral density (CMO:0001728)104944455181709989Rat
2316949Gluco60Glucose level QTL 603.7blood glucose amount (VT:0000188)blood glucose level (CMO:0000046)1014487011107057807Rat
2306970Anxrr22Anxiety related response QTL 225.95fear/anxiety-related behavior trait (VT:1000241)number of periods of voluntary immobility (CMO:0001045)106134527698211570Rat
1359017Hrtrt21Heart rate QTL 212.4heart pumping trait (VT:2000009)heart rate (CMO:0000002)105177294096772940Rat
2306787Ean3Experimental allergic neuritis QTL 33.1nervous system integrity trait (VT:0010566)body weight loss (CMO:0001399)105379738566979128Rat
2312672Insul15Insulin level QTL 150.01blood insulin amount (VT:0001560)serum insulin level (CMO:0000358)1057134272102134272Rat
2317029Aia19Adjuvant induced arthritis QTL 192.98joint integrity trait (VT:0010548)left rear ankle joint diameter (CMO:0002149)1066978955107211142Rat
8662860Vetf10Vascular elastic tissue fragility QTL 10artery integrity trait (VT:0010639)number of ruptures of the internal elastic lamina of the abdominal aorta and iliac arteries (CMO:0002562)10615418273453136Rat
61387Bp1Blood pressure QTL 15.1arterial blood pressure trait (VT:2000000)diastolic blood pressure (CMO:0000005)1051770177107211142Rat
2317039Aia6Adjuvant induced arthritis QTL 64.31joint integrity trait (VT:0010548)right rear ankle joint diameter (CMO:0002150)1066978955107211142Rat
2317043Aia7Adjuvant induced arthritis QTL 73.82joint integrity trait (VT:0010548)left rear ankle joint diameter (CMO:0002149)103756507982565079Rat
2317042Aia20Adjuvant induced arthritis QTL 203.38joint integrity trait (VT:0010548)right rear ankle joint diameter (CMO:0002150)103756507982565079Rat
70363Bp71Blood pressure QTL 710.04arterial blood pressure trait (VT:2000000)mean arterial blood pressure (CMO:0000009)106134527681714865Rat
61402Niddm3Non-insulin dependent diabetes mellitus QTL 34.58blood glucose amount (VT:0000188)blood glucose level (CMO:0000046)106134541382564856Rat
70364Bp72Blood pressure QTL 72arterial blood pressure trait (VT:2000000)mean arterial blood pressure (CMO:0000009)105112110096121100Rat
10450498Bp384Blood pressure QTL 3840.002arterial blood pressure trait (VT:2000000)mean arterial blood pressure (CMO:0000009)1067750049107211142Rat
2293698Bss43Bone structure and strength QTL 435.330.0001lumbar vertebra size trait (VT:0010518)lumbar vertebra cross-sectional area (CMO:0001689)1059209888104209888Rat
631530Tls3T-lymphoma susceptibility QTL 300.0001thymus integrity trait (VT:0010555)percentage of study population developing T-cell lymphomas during a period of time (CMO:0001911)105177461295600334Rat
631535Cm51Cardiac mass QTL 513heart mass (VT:0007028)calculated heart weight (CMO:0000073)105178628291669536Rat
8552805Bw145Body weight QTL 1452.2body mass (VT:0001259)change in body weight to body weight ratio (CMO:0002216)104194452678307017Rat
631267Cia20Collagen induced arthritis QTL 203.2joint integrity trait (VT:0010548)joint inflammation composite score (CMO:0000919)1023444813104060283Rat
2293705Bmd25Bone mineral density QTL 257.10.0001femur mineral mass (VT:0010011)compact volumetric bone mineral density (CMO:0001730)104944455181709989Rat
631269Cia22Collagen induced arthritis QTL 228.9joint integrity trait (VT:0010548)joint inflammation composite score (CMO:0000919)1040035094104060283Rat
631268Cia21Collagen induced arthritis QTL 213.1joint integrity trait (VT:0010548)joint inflammation composite score (CMO:0000919)1014487011104060283Rat
7207811Bmd90Bone mineral density QTL 905.2femur size trait (VT:1000369)femoral neck cross-sectional area (CMO:0001697)104944455181709989Rat
631270Cia23Collagen induced arthritis QTL 233.9joint integrity trait (VT:0010548)joint inflammation composite score (CMO:0000919)1040035094104060283Rat
631526Bp76Blood pressure QTL 760.0001arterial blood pressure trait (VT:2000000)systolic blood pressure (CMO:0000004)106134541366743655Rat
7411614Foco18Food consumption QTL 180.001eating behavior trait (VT:0001431)feed conversion ratio (CMO:0001312)104444169989441699Rat
631547Bp87Blood pressure QTL 874.5arterial blood pressure trait (VT:2000000)systolic blood pressure (CMO:0000004)104736947092369470Rat
61427Cia16Collagen induced arthritis QTL 163.2joint integrity trait (VT:0010548)joint inflammation composite score (CMO:0000919)10635789696121100Rat
2312662Slep8Serum leptin concentration QTL 80.05blood leptin amount (VT:0005667)serum leptin level (CMO:0000780)1057134272102134272Rat
2292440Bp312Blood pressure QTL 312arterial blood pressure trait (VT:2000000)mean arterial blood pressure (CMO:0000009)106775004968164786Rat
2292441Bp308Blood pressure QTL 308arterial blood pressure trait (VT:2000000)mean arterial blood pressure (CMO:0000009)102760646872606468Rat
2301405Cm69Cardiac mass QTL 690.031heart mass (VT:0007028)heart wet weight to body weight ratio (CMO:0002408)106631944767750281Rat
2312668Scl65Serum cholesterol level QTL 650.001blood cholesterol amount (VT:0000180)serum total cholesterol level (CMO:0000363)1057134272102134272Rat
631542Bp82Blood pressure QTL 826.8arterial blood pressure trait (VT:2000000)systolic blood pressure (CMO:0000004)102652195798952741Rat


Additional Information

Database Acc Id Source(s)
NCBI Gene Eae18b


Nomenclature History
Date Current Symbol Current Name Previous Symbol Previous Name Description Reference Status
2006-04-14 Eae18b  Experimental allergic encephalomyelitis QTL 18b  Eae20  Experimental allergic encephalomyelitis QTL 20  Symbol and Name updated 1299863 APPROVED

RGD Curation Notes
Note Type Note Reference
qtl_cross_type Intercross  
qtl_disease syntenic region on human chromosome 17q11 displays linkage to multiple sclerosis 1302437