Am15 QTL Report (Rattus norvegicus) - Rat Genome Database
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QTL: Am15 (Aortic mass QTL 15) Rattus norvegicus

Symbol: Am15
Name: Aortic mass QTL 15
RGD ID: 12903269
Also known as: CakmC10QTL
Trait: aorta mass   (VT:0002845)    
Measurement Type: aorta weight to aorta length to body weight ratio   (CMO:0002722)    
LOD Score: Not Available
P Value: 0.042
Variance: Not Available
Position
Rat AssemblyChrPosition (strand)SourceJBrowse
Rnor_6.01068,697,928 - 70,167,191RGD_MAPPER_PIPELINERnor6.0
Rnor_5.01068,361,762 - 69,797,898RGD_MAPPER_PIPELINERnor5.0
RGSC_v3.41069,555,329 - 71,032,765RGD_MAPPER_PIPELINERGSC3.4
Cross Type: Not Available
Strains Crossed: SS.LEW-(D10Chm128-D10Chm169)/Ayd 
JBrowse: View Region in Genome Browser (JBrowse)
Model



Phenotype Annotations     Click to see Annotation Detail View

Mammalian Phenotype
Experimental Data Annotations     Click to see Annotation Detail View

Experimental Condition

Measurement Method

Vertebrate Trait
aorta mass  (IDA)

Rat Strain

References


Region

Genes in Region
The following Genes overlap with this region.    Full Report CSV TAB Printer Analysis Tools
RGD IDSymbolNameChrStartStopSpecies
3644Ccl11C-C motif chemokine ligand 11106943496569439566Rat
3645Ccl2C-C motif chemokine ligand 2106941206569413863Rat
2017Asic2acid sensing ion channel subunit 2106824780069347223Rat
1309875Lig3DNA ligase 3107013473470158051Rat
1359152Ccl7C-C motif chemokine ligand 7106942308369424933Rat
1309255Ccl12chemokine (C-C motif) ligand 12106947686669478416Rat
1560058Phb-ps1prohibitin, pseudogene 1106892541668926320Rat
1359453Cct6bchaperonin containing TCP1 subunit 6B107006947970118194Rat
727916Rfflring finger and FYVE-like domain containing E3 ubiquitin protein ligase107015762170220618Rat
1565522Tmem132etransmembrane protein 132E106973553469794975Rat
1562573Zfp830zinc finger protein 830107011825070119714Rat
1586495Ccl1C-C motif chemokine ligand 1106953497669537836Rat
7489011Mir6327microRNA 6327106897760168977733Rat
7510604LOC102547784uncharacterized LOC102547784106967443069683223Rat
7607868LOC102547954uncharacterized LOC102547954107013351070134603Rat
9084586C10H17orf102chromosome 10 open reading frame, human C17orf102106973511669737570Rat
9278651LOC103693401uncharacterized LOC103693401106895348768957745Rat
9332269LOC103693402uncharacterized LOC103693402106906829969071180Rat
9359311LOC103693444glyceraldehyde-3-phosphate dehydrogenase-like106917698169185205Rat
9456662LOC103693403uncharacterized LOC103693403107012661070129053Rat
11472642LOC108352113transcription factor BTF3 homolog 4 pseudogene107008499270086973Rat
11435226LOC108352208uncharacterized LOC108352208106934715269362721Rat
11493017LOC108352112uncharacterized LOC108352112106946183869470696Rat

Markers in Region
The following Markers overlap with this region.    Full Report CSV TAB Printer Gviewer
RGD IDSymbolExpected SizeChrStartStopSpeciesMatch
37502D10Rat70127106912924869129386Ratregion
37084D10Rat28244106910614769106433Ratregion
37170D10Rat123202106882434968824552Ratregion
38936D10Rat98235106934823369348459Ratregion
41468D10Rat155174106938559569385767Ratregion
42926D10Rat210160106923094369231114Ratregion
42926D10Rat210160106920480369204972Ratregion
44758D10Got84125106912871469128835Ratregion
66552D10Mco1187106912360369123793Ratregion
1578847D10Chm131164106970680469706967Ratregion
1578900D10Chm166237106946518969465425Ratregion
1578907D10Chm129225106959657669596800Ratregion
1578918D10Chm167247106974204369742287Ratregion
1578931D10Chm171232107016696070167191Ratregion
1578987D10Chm229233106869792868698159Ratregion
1578992D10Chm170224107013713170137354Ratregion
1579015D10Chm128172106963889869639069Ratregion
1579024D10Chm168230106974950469749733Ratregion
1579039D10Chm169228106980879369809020Ratregion
1579051D10Chm130245106969978569700029Ratregion
1579182D10Chm186182107008923570089416Ratregion
1579193D10Chm165194106940684269407035Ratregion
1642087D10Mco84165106991083269910996Ratregion
1642091D10Mco85345107001262870012972Ratregion
2308866D10Kini1178106942947069429647Ratregion
5036145D11Bhm13693106917346969173561Ratregion
5036486Scya274106941258169412654Ratregion
5036899AU049558292106907070969071000Ratregion
5031338PMC145384P1658106941291269413569Ratregion
5035040UniSTS:259419436106978558869786023Ratregion
5035042D11Pas33242107006543870065679Ratregion
5035044D11Pas4281106961610169616181Ratregion
5028003M23501186106953503069535215Ratregion
5028143D11Mit68.1138106917398769174124Ratregion
5057938BF392929139106881209768812235Ratregion
505219122.MMHAP6FLH1.seq153106973636569736517Ratregion
5055579RH143882128106931421869314345Ratregion
5041704RH129010220107012055870120777Ratregion
5048888RH133164219106942461369424830Ratregion
5049226RH133358198107015769270157889Ratregion
5039866RH127952215107015781570158029Ratregion
5079616RH141104207107015591670156122Ratregion
5071084RH134877186107013353470133719Ratregion
5071072RH134870195106941355569413749Ratregion
5073796RH137643128107015882670158953Ratregion
5065024BE108934161106882153568821695Ratregion
5068224AU047274134106900025769000390Ratregion
5068942AU046828244107002571570025958Ratregion
5065468BE109015157107014582970145985Ratregion
5061374BI293876150106974547469745623Ratregion
5082257BE119054202106875551368755714Ratregion
5087763D11Bhm14179106978610769786185Ratregion
5088092Scya11102106943840169438502Ratregion
5087759D11Bhm13762106925525169255312Ratregion
5087777RH125886235107015779770158031Ratregion
5085072D11Pas27117106991653569916651Ratregion
5085074D11Pas39563106968058369681145Ratregion
5085076D11Pas45157106968931569689471Ratregion
5081060RH141942212107011937670119587Ratregion
5504833ha22370106878082468781351Ratregion
5505184Lig30107014402670144890Ratregion
5506483RH71331598107006960970070206Ratregion
5502084MARC_3929-3930:996679185:11066107015043670151501Ratregion
Position Markers

Flank 1: (D10Chm229)
Rat AssemblyChrPosition (strand)Source
Rnor_6.01068,697,928 - 68,698,159NCBI
Rnor_5.01068,361,762 - 68,361,993UniSTS
RGSC_v3.41069,555,329 - 69,555,560UniSTS
Celera1065,274,629 - 65,274,860UniSTS
Cytogenetic Map10q26UniSTS
Flank 2: (D10Chm171)
Rat AssemblyChrPosition (strand)Source
Rnor_6.01070,166,960 - 70,167,191NCBI
Rnor_5.01069,797,667 - 69,797,898UniSTS
RGSC_v3.41071,032,534 - 71,032,765UniSTS
Celera1066,694,510 - 66,694,687UniSTS
Cytogenetic Map10q26UniSTS


QTLs in Region (Rnor_6.0)
The following QTLs overlap with this region.    Full Report CSV TAB Printer Gviewer
RGD IDSymbolNameLODP ValueTraitSub TraitChrStartStopSpecies
8662860Vetf10Vascular elastic tissue fragility QTL 10artery integrity trait (VT:0010639)number of ruptures of the internal elastic lamina of the abdominal aorta and iliac arteries (CMO:0002562)10622909575983805Rat
61427Cia16Collagen induced arthritis QTL 163.2joint integrity trait (VT:0010548)joint inflammation composite score (CMO:0000919)10642907599492409Rat
2303118Mamtr7Mammary tumor resistance QTL 70.003mammary gland integrity trait (VT:0010552)mammary tumor growth rate (CMO:0000344)109841807108540162Rat
2301967Cm73Cardiac mass QTL 734.55heart left ventricle mass (VT:0007031)heart left ventricle weight to body weight ratio (CMO:0000530)101482789492423564Rat
631268Cia21Collagen induced arthritis QTL 213.1joint integrity trait (VT:0010548)joint inflammation composite score (CMO:0000919)1014827894107857673Rat
2316949Gluco60Glucose level QTL 603.7blood glucose amount (VT:0000188)blood glucose level (CMO:0000046)1014827894110992275Rat
1554317Bmd4Bone mineral density QTL 49.40.0001lumbar vertebra mineral mass (VT:0010511)volumetric bone mineral density (CMO:0001553)1020170031102897474Rat
70223Bp57Blood pressure QTL 575arterial blood pressure trait (VT:2000000)systolic blood pressure (CMO:0000004)102152390683549467Rat
70188BpQTLcluster1Blood pressure QTL cluster 14.864arterial blood pressure trait (VT:2000000)diastolic blood pressure (CMO:0000005)12152390690312401Rat
70188BpQTLcluster1Blood pressure QTL cluster 14.864arterial blood pressure trait (VT:2000000)systolic blood pressure (CMO:0000004)12152390690312401Rat
70188BpQTLcluster1Blood pressure QTL cluster 14.864arterial blood pressure trait (VT:2000000)mean arterial blood pressure (CMO:0000009)12152390690312401Rat
70188BpQTLcluster1Blood pressure QTL cluster 14.864arterial blood pressure trait (VT:2000000)pulse pressure (CMO:0000292)12152390690312401Rat
70198BpQTLcluster9Blood pressure QTL cluster 92.94arterial blood pressure trait (VT:2000000)mean arterial blood pressure (CMO:0000009)102152390690312401Rat
724556Pur2Proteinuria QTL 25.5urine protein amount (VT:0005160)urine protein level (CMO:0000591)102290149793886300Rat
1331791Cm31Cardiac mass QTL 313.84606heart mass (VT:0007028)heart wet weight (CMO:0000069)1023861015112626471Rat
631267Cia20Collagen induced arthritis QTL 203.2joint integrity trait (VT:0010548)joint inflammation composite score (CMO:0000919)1024483076107857673Rat
61325Aia5Adjuvant induced arthritis QTL 50.01joint integrity trait (VT:0010548)joint inflammation composite score (CMO:0000919)1024483076107857673Rat
61354Pia10Pristane induced arthritis QTL 100.01joint integrity trait (VT:0010548)joint inflammation composite score (CMO:0000919)1024483076107857673Rat
1298069Bp168Blood pressure QTL 1685.5blood pressure trait (VT:0000183)systolic blood pressure (CMO:0000004)1027237530101482600Rat
631542Bp82Blood pressure QTL 826.8arterial blood pressure trait (VT:2000000)systolic blood pressure (CMO:0000004)1027237530102427718Rat
2300171Bmd58Bone mineral density QTL 584.90.0001lumbar vertebra mineral mass (VT:0010511)volumetric bone mineral density (CMO:0001553)102878928073789280Rat
2292441Bp308Blood pressure QTL 308arterial blood pressure trait (VT:2000000)mean arterial blood pressure (CMO:0000009)103009990975099909Rat
10402859Bp381Blood pressure QTL 3810.002arterial blood pressure trait (VT:2000000)mean arterial blood pressure (CMO:0000009)103009990975099909Rat
724527Bp148Blood pressure QTL 1480.0001arterial blood pressure trait (VT:2000000)mean arterial blood pressure (CMO:0000009)103098380575983805Rat
1576311Pia26Pristane induced arthritis QTL 26joint integrity trait (VT:0010548)joint inflammation composite score (CMO:0000919)103191939778343192Rat
1578779Tcas10Tongue tumor susceptibility QTL 103.12tongue integrity trait (VT:0010553)number of squamous cell tumors of the tongue with diameter greater than 3 mm (CMO:0001950)103317903078179030Rat
631557Bp136Blood pressure QTL 1360.003arterial blood pressure trait (VT:2000000)systolic blood pressure (CMO:0000004)103334319278343192Rat
1576319Cia29Collagen induced arthritis QTL 29joint integrity trait (VT:0010548)joint inflammation composite score (CMO:0000919)103513942480139424Rat
6893342Cm78Cardiac mass QTL 780.10.88heart mass (VT:0007028)heart weight to body weight ratio (CMO:0000074)103618592982675365Rat
631552Vetf2Vascular elastic tissue fragility QTL 24.50.0002aorta elastic tissue integrity trait (VT:0010556)artery internal elastic lamina non-tumorous lesion count (CMO:0001913)103618592995845311Rat
2317042Aia20Adjuvant induced arthritis QTL 203.38joint integrity trait (VT:0010548)right rear ankle joint diameter (CMO:0002150)104051404485514044Rat
2317043Aia7Adjuvant induced arthritis QTL 73.82joint integrity trait (VT:0010548)left rear ankle joint diameter (CMO:0002149)104051404485514044Rat
1576308Schws1Schwannoma susceptibility QTL 10.0041nervous system integrity trait (VT:0010566)percentage of study population developing trigeminal nerve neurilemmomas during a period of time (CMO:0002017)1041260363106105607Rat
631269Cia22Collagen induced arthritis QTL 228.9joint integrity trait (VT:0010548)joint inflammation composite score (CMO:0000919)1041260363107857673Rat
631270Cia23Collagen induced arthritis QTL 233.9joint integrity trait (VT:0010548)joint inflammation composite score (CMO:0000919)1041260363107857673Rat
8552805Bw145Body weight QTL 1452.2body mass (VT:0001259)change in body weight to body weight ratio (CMO:0002216)104318865981042642Rat
1298078Stresp5Stress response QTL 52.990.00025blood corticosterone amount (VT:0005345)plasma corticosterone level (CMO:0001173)1043289657108540162Rat
61463Bp12Blood pressure QTL 126.30.0001arterial blood pressure trait (VT:2000000)systolic blood pressure (CMO:0000004)104370495588704955Rat
2300218Hpcl2Hepatic cholesterol level QTL 2liver cholesterol amount (VT:0010498)liver cholesterol level (CMO:0001597)104659302198939209Rat
9589030Epfw9Epididymal fat weight QTL 919.240.001epididymal fat pad mass (VT:0010421)epididymal fat pad weight to body weight ratio (CMO:0000658)104684834691848346Rat
7411614Foco18Food consumption QTL 180.001eating behavior trait (VT:0001431)feed conversion ratio (CMO:0001312)104684834691848346Rat
8694173Bw149Body weight QTL 1494.380.001body mass (VT:0001259)body weight gain (CMO:0000420)104684834691848346Rat
631547Bp87Blood pressure QTL 874.5arterial blood pressure trait (VT:2000000)systolic blood pressure (CMO:0000004)105063833795638337Rat
2293652Bmd22Bone mineral density QTL 224.90.0001femur mineral mass (VT:0010011)total volumetric bone mineral density (CMO:0001728)105128920384596393Rat
2293669Bmd33Bone mineral density QTL 334.50.0001femur strength trait (VT:0010010)femoral neck polar moment of inertia (CMO:0001670)105128920384596393Rat
2293679Bmd30Bone mineral density QTL 303.50.0001femur mineral mass (VT:0010011)total volumetric bone mineral density (CMO:0001728)105128920384596393Rat
2293705Bmd25Bone mineral density QTL 257.10.0001femur mineral mass (VT:0010011)cortical volumetric bone mineral density (CMO:0001730)105128920384596393Rat
7207811Bmd90Bone mineral density QTL 905.2femur size trait (VT:1000369)femoral neck cross-sectional area (CMO:0001697)105128920384596393Rat
1549846Scl47Serum cholesterol level QTL 473.6blood cholesterol amount (VT:0000180)serum total cholesterol level (CMO:0000363)105310471898104718Rat
61387Bp1Blood pressure QTL 15.1arterial blood pressure trait (VT:2000000)systolic blood pressure (CMO:0000004)1053621375112626471Rat
61387Bp1Blood pressure QTL 15.1arterial blood pressure trait (VT:2000000)diastolic blood pressure (CMO:0000005)1053621375112626471Rat
631530Tls3T-lymphoma susceptibility QTL 300.0001thymus integrity trait (VT:0010555)percentage of study population developing T-cell lymphomas during a period of time (CMO:0001911)105362581598939209Rat
631535Cm51Cardiac mass QTL 513heart mass (VT:0007028)calculated heart weight (CMO:0000073)105363748594807701Rat
1359017Hrtrt21Heart rate QTL 212.4heart pumping trait (VT:2000009)heart rate (CMO:0000002)1055224855100224855Rat
2306787Ean3Experimental allergic neuritis QTL 33.1nervous system integrity trait (VT:0010566)body weight loss (CMO:0001399)105567897669385767Rat
70171Cari1Carrageenan-induced inflammation QTL 14.90.0005hypodermis integrity trait (VT:0010550)inflammatory exudate volume (CMO:0001429)1055678976112626471Rat
70164Bw21Body weight QTL 214.360.00005body mass (VT:0001259)body weight (CMO:0000012)1055679084102427604Rat
1354608Cm33Cardiac mass QTL 332.8heart left ventricle mass (VT:0007031)heart left ventricle wet weight (CMO:0000071)1056698730101698730Rat
1549831Bss6Bone structure and strength QTL 64lumbar vertebra strength trait (VT:0010574)vertebra ultimate force (CMO:0001678)1060450007105450007Rat
2312662Slep8Serum leptin concentration QTL 80.05blood leptin amount (VT:0005667)serum leptin level (CMO:0000780)1060875260105875260Rat
2312668Scl65Serum cholesterol level QTL 650.001blood cholesterol amount (VT:0000180)serum total cholesterol level (CMO:0000363)1060875260105875260Rat
2312672Insul15Insulin level QTL 150.01blood insulin amount (VT:0001560)serum insulin level (CMO:0000358)1060875260105875260Rat
2293698Bss43Bone structure and strength QTL 435.330.0001lumbar vertebra size trait (VT:0010518)lumbar vertebra cross-sectional area (CMO:0001689)1062096293107096293Rat
1331839Eae18bExperimental allergic encephalomyelitis QTL 18b5.80.03nervous system integrity trait (VT:0010566)experimental autoimmune encephalomyelitis severity score (CMO:0001419)106455091270202084Rat
70363Bp71Blood pressure QTL 710.04arterial blood pressure trait (VT:2000000)mean arterial blood pressure (CMO:0000009)106464817584601269Rat
2306970Anxrr22Anxiety related response QTL 225.95fear/anxiety-related behavior trait (VT:1000241)number of periods of voluntary immobility (CMO:0001045)1064648175101691360Rat
1558643Cm44Cardiac mass QTL 444.80.0000368heart mass (VT:0007028)heart wet weight (CMO:0000069)1064648175102149713Rat
6893336Cm75Cardiac mass QTL 750.10.87heart mass (VT:0007028)heart weight to body weight ratio (CMO:0000074)1064648175102149713Rat
631526Bp76Blood pressure QTL 760.0001arterial blood pressure trait (VT:2000000)systolic blood pressure (CMO:0000004)106464831169123603Rat
61402Niddm3Non-insulin dependent diabetes mellitus QTL 34.58blood glucose amount (VT:0000188)blood glucose level (CMO:0000046)106464831185513822Rat
61449Ciaa2CIA Autoantibody QTL 27.1blood autoantibody amount (VT:0003725)calculated serum anti-type 2 collagen antibody titer (CMO:0001279)1065590122110590122Rat
2313103Bss80Bone structure and strength QTL 8020.0001tibia strength trait (VT:1000284)tibia midshaft endosteal cross-sectional area (CMO:0001716)1065992275110992275Rat
2313105Bss79Bone structure and strength QTL 791.80.0001tibia size trait (VT:0100001)tibia midshaft cross-sectional area (CMO:0001717)1065992275110992275Rat
7387312Bw125Body weight QTL 12530.0047retroperitoneal fat pad mass (VT:0010430)retroperitoneal fat pad weight (CMO:0000356)1067880046112626471Rat
1581559Eae18Experimental allergic encephalomyelitis QTL 180.00002nervous system integrity trait (VT:0010566)experimental autoimmune encephalomyelitis severity score (CMO:0001419)1067988218110992091Rat
2298481Eau9Experimental allergic uveoretinitis QTL 90.0169uvea integrity trait (VT:0010551)experimental autoimmune uveitis score (CMO:0001504)106830503785514044Rat
2301405Cm69Cardiac mass QTL 690.031heart mass (VT:0007028)heart wet weight to body weight ratio (CMO:0002408)106869792870167191Rat
11565453Kidm58Kidney mass QTL 580.002kidney mass (VT:0002707)both kidneys wet weight to body weight ratio (CMO:0000340)106869792870167191Rat
12903252Cm113Cardiac mass QTL 1130.047heart left ventricle mass (VT:0007031)heart left ventricle weight to body weight ratio (CMO:0000530)106869792870167191Rat
12903266Cm114Cardiac mass QTL 1140.02heart right ventricle mass (VT:0007033)heart right ventricle weight to body weight ratio (CMO:0000914)106869792870167191Rat
12903269Am15Aortic mass QTL 150.042aorta mass (VT:0002845)aorta weight to aorta length to body weight ratio (CMO:0002722)106869792870167191Rat
12880370Cm105Cardiac mass QTL 1050.008heart mass (VT:0007028)heart wet weight to body weight ratio (CMO:0002408)106869792870581793Rat
12880371Cm106Cardiac mass QTL 1060.007heart left ventricle mass (VT:0007031)heart left ventricle weight to body weight ratio (CMO:0000530)106869792870581793Rat
12880372Am12Aortic mass QTL 120.003aorta mass (VT:0002845)aorta weight to aorta length to body weight ratio (CMO:0002722)106869792870581793Rat
12880375Kidm66Kidney mass QTL 660.009kidney mass (VT:0002707)both kidneys wet weight to body weight ratio (CMO:0000340)106869792870581793Rat
1357344Bp249Blood pressure QTL 2490.0001arterial blood pressure trait (VT:2000000)systolic blood pressure (CMO:0000004)1069123603101482600Rat
631565Hcuc4Hepatic copper content QTL 44.15hepatic copper amount (VT:0003065)liver copper weight to liver dry weight ratio (CMO:0001512)106934845975983662Rat
8657410Bp374Blood pressure QTL 374heart left ventricle size trait (VT:0002753)heart left ventricular end-diastolic diameter (CMO:0000982)106938559570167191Rat
2317029Aia19Adjuvant induced arthritis QTL 192.98joint integrity trait (VT:0010548)left rear ankle joint diameter (CMO:0002149)1069385595112626471Rat
2317039Aia6Adjuvant induced arthritis QTL 64.31joint integrity trait (VT:0010548)right rear ankle joint diameter (CMO:0002150)1069385595112626471Rat
1579917Bp282Blood pressure QTL 2820.001arterial blood pressure trait (VT:2000000)mean arterial blood pressure (CMO:0000009)106980879370581793Rat
2289985Bp305Blood pressure QTL 305arterial blood pressure trait (VT:2000000)systolic blood pressure (CMO:0000004)106991083276109716Rat
2292440Bp312Blood pressure QTL 312arterial blood pressure trait (VT:2000000)mean arterial blood pressure (CMO:0000009)107016696070581793Rat
10450498Bp384Blood pressure QTL 3840.002arterial blood pressure trait (VT:2000000)mean arterial blood pressure (CMO:0000009)1070166960112626471Rat


Additional Information

RGD Curation Notes
Note Type Note Reference
qtl_general number of animals used: 8 gender: male 1599557
qtl_general also affects heart mass, heart right and left ventricle mass and kidney mass, but not body mass or blood pressure 1599557
qtl_map 1.7 Mb 1599557
qtl_statistics_details software package used: ANOVA followed by Dunnett test in the SYSTAT 9 program 1599557
qtl_trait_method measurement method: selected males were weaned at 21 days of age then fed 2% NaCl diet starting from 35 days of age, at 14 weeks animals were decapitated, organs removed, blotted and weighed 1599557
qtl_trait_method aorta section was from the diaphragm to the first intercostal artery 1599557