Bp87 QTL Report (Rattus norvegicus) - Rat Genome Database

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QTL Registration

QTL: Bp87 (Blood pressure QTL 87) Rattus norvegicus

Symbol: Bp87
Name: Blood pressure QTL 87
RGD ID: 631547
Trait: arterial blood pressure trait   (VT:2000000)    
Measurement Type: systolic blood pressure   (CMO:0000004)    
LOD Score: 4.5
P Value: Not Available
Variance: Not Available
Position
Rat AssemblyChrPosition (strand)SourceJBrowse
GRCr81047,869,129 - 92,869,129RGD_MAPPER_PIPELINE
mRatBN7.21047,369,470 - 92,369,470RGD_MAPPER_PIPELINEmRatBN7.2
Rnor_6.01050,638,337 - 95,638,337RGD_MAPPER_PIPELINERnor6.0
Rnor_5.01050,372,987 - 95,372,987RGDRnor5.0
RGSC_v3.41096,799,833 - 106,897,319RGDRGSC3.4
Cross Type: intercross
Strains Crossed: WKY/Izm SHRSP/Izm 
JBrowse: View Region in Genome Browser (JBrowse)
Model




  
Object Symbol
Species
Term
Qualifier
Evidence
With
Reference
Notes
Source
Original Reference(s)
Bp87Rathypertension  IDA 619634 RGD 

Object Symbol
Species
Term
Qualifier
Evidence
With
Reference
Notes
Source
Original Reference(s)
Bp87Ratincreased systemic arterial blood pressure  QTM 619634 RGD 

Clinical Measurement
Object Symbol
Species
Term
Qualifier
Evidence
With
Reference
Notes
Source
Original Reference(s)
Bp87Ratsystolic blood pressure  IDA 619634 RGD 

Experimental Condition
Object Symbol
Species
Term
Qualifier
Evidence
With
Reference
Notes
Source
Original Reference(s)
Bp87Ratcontrolled sodium content drinking water  IDA 619634 RGD 

Measurement Method
Object Symbol
Species
Term
Qualifier
Evidence
With
Reference
Notes
Source
Original Reference(s)
Bp87Rattail cuff photoplethysmography  IDA 619634 RGD 

Rat Strain
Object Symbol
Species
Term
Qualifier
Evidence
With
Reference
Notes
Source
Original Reference(s)
Bp87RatSHRSP/Izm  IEA 619634 RGD 
Bp87RatWKY/Izm  IEA 619634 RGD 

Vertebrate Trait
Object Symbol
Species
Term
Qualifier
Evidence
With
Reference
Notes
Source
Original Reference(s)
Bp87Ratarterial blood pressure trait  IDA 619634 RGD 


#
Reference Title
Reference Citation
1. Aging and salt-loading modulate blood pressure QTLs in rats. Mashimo T, etal., Am J Hypertens 1999 Nov;12(11 Pt 1):1098-104.


1 to 20 of 1274 rows
The following Genes overlap with this region.    Full Report CSV TAB Printer Analysis Tools
RGD ID
Symbol
Name
Chr
Start
Stop
Species
1308617Zfp287zinc finger protein 287104739565047415610Rat
11446408Trnaw-cca3transfer RNA tryptophan (anticodon CCA) 3104743153447431605Rat
40943474LOC120095502U6 spliceosomal RNA104743497547435080Rat
41327418LOC120095403small nucleolar RNA SNORA67104744813747448270Rat
1561950Zfp286azinc finger protein 286A104745046947461267Rat
1309749Trim16tripartite motif-containing 16104748598247509010Rat
1563889Fbxw10F-box and WD repeat domain containing 10104751331347551909Rat
41224105LOC120095495U4 spliceosomal RNA104753320347533317Rat
1586539Tvp23btrans-golgi network vesicle protein 23 homolog B104755378947565203Rat
41394133LOC120095116uncharacterized LOC120095116104758840047590766Rat
7527442LOC102552952uncharacterized LOC102552952104761660147625398Rat
2323961Cdrt4CMT1A duplicated region transcript 4104762547047657493Rat
1310582Tekt3tektin 3104772963547763589Rat
3359Pmp22peripheral myelin protein 22104779570947825715Rat
2321712Ubbl2ubiquitin B like 2104791045847910703Rat
40937829LOC120095507U6 spliceosomal RNA104840259048402695Rat
41034231LOC120095117uncharacterized LOC120095117104853219348539710Rat
1307326Hs3st3b1heparan sulfate-glucosamine 3-sulfotransferase 3B1104856147348593970Rat
1594623Cox10cytochrome c oxidase assembly factor heme A:farnesyltransferase COX10104863099348742805Rat
41035134LOC120095119uncharacterized LOC120095119104869289748706492Rat

1 to 20 of 1274 rows
1 to 20 of 1736 rows
The following Markers overlap with this region.    Full Report CSV TAB Printer Gviewer
RGD ID
Symbol
Expected Size
Chr
Start
Stop
Species
Match
10062D10Wox19230108541268585412915Ratregion
10141D10Wox15254106322103763221291Ratregion
10142D10Arb9129106322109463221223Ratregion
10195D10Wox14158105477580754775965Ratregion
10196D10Mgh22270105477574554776015Ratregion
10662D10Wox23258108097644580976703Ratregion
10664D10Uwm1158105467188954672047Ratregion
10926D10Wox21130108913584589135975Ratregion
10949D10Wox11150105178628251786432Ratregion
10980D10Wox16125108051612580516250Ratregion
10981D10Arb21199108051614780516346Ratregion
10982D10Mit13165108051613480516299Ratregion
10995D10Wox24138106381361463813752Ratregion
11137D10Wox17153108705512187055282Ratregion
11169D10Mgh21140108853913988539279Ratregion
33846D10Mit2188106364253963642727Ratregion
34176D10Mgh24122105259574452595866Ratregion
34274D10Mgh5223108256485682565079Ratregion
34320D10Mgh7215105409867454098889Ratregion
34445D10Mgh6137106134527661345413Ratregion
1 to 20 of 1736 rows

Flank 1: (D10Mgh1)
Rat AssemblyChrPosition (strand)Source
Celera10102,748,696 - 102,748,839UniSTS
RH 2.0 Map101407.7RGD
Cytogenetic Map10 RGD
Peak: (D10Mit11)
Rat AssemblyChrPosition (strand)Source
RGSC_v3.410101,848,470 - 101,848,683RGD
RGSC_v3.110101,862,784 - 101,863,126RGD
Celera1095,940,193 - 95,940,406UniSTS
RH 3.4 Map101094.7RGD
RH 2.0 Map101223.1RGD
Cytogenetic Map10 RGD
Flank 2: (D10Mgh4)
Rat AssemblyChrPosition (strand)Source
GRCr81092,869,025 - 92,869,129 (+)Marker Load Pipeline
mRatBN7.21092,369,364 - 92,369,470 (+)MAPPER
Rnor_6.01095,638,234 - 95,638,337NCBI
Rnor_5.01095,372,884 - 95,372,987UniSTS
RGSC_v3.41096,799,833 - 96,799,937RGD
RGSC_v3.41096,799,834 - 96,799,937UniSTS
RGSC_v3.11096,814,203 - 96,814,307RGD
Celera1091,034,140 - 91,034,243UniSTS
RH 3.4 Map101021.3UniSTS
RH 3.4 Map101021.3RGD
RH 2.0 Map101120.3RGD
SHRSP x BN Map1073.41RGD
FHH x ACI Map1076.95RGD
Cytogenetic Map10q32.1UniSTS


1 to 10 of 184 rows
The following QTLs overlap with this region.    Full Report CSV TAB Printer Gviewer
RGD ID
Symbol
Name
LOD
P Value
Trait
Sub Trait
Chr
Start
Stop
Species
61441Btemp1Thermal response to stress QTL 14body temperature trait (VT:0005535)core body temperature (CMO:0001036)103539245763642539Rat
1549846Scl47Serum cholesterol level QTL 473.6blood cholesterol amount (VT:0000180)serum total cholesterol level (CMO:0000363)105057470795574707Rat
9589136Insul27Insulin level QTL 2710.460.001blood insulin amount (VT:0001560)plasma insulin level (CMO:0000342)101147401056474010Rat
1578779Tcas10Tongue tumor susceptibility QTL 103.12tongue integrity trait (VT:0010553)number of squamous cell tumors of the tongue with diameter greater than 3 mm (CMO:0001950)103129743976297439Rat
631565Hcuc4Hepatic copper content QTL 44.15liver copper amount (VT:0003065)liver copper weight to liver dry weight ratio (CMO:0001512)106694181373452992Rat
631564Apr3Acute phase response QTL 33.9blood interleukin-6 amount (VT:0008595)plasma interleukin-6 level (CMO:0001927)101527595560275955Rat
631552Vetf2Vascular elastic tissue fragility QTL 24.50.0002aorta elastic tissue integrity trait (VT:0010556)artery internal elastic lamina non-tumorous lesion count (CMO:0001913)104114263386142633Rat
61449Ciaa2CIA Autoantibody QTL 27.1blood autoantibody amount (VT:0003725)calculated serum anti-type 2 collagen antibody titer (CMO:0001279)1063221094107211142Rat
631555Bp134Blood pressure QTL 1340.001arterial blood pressure trait (VT:2000000)systolic blood pressure (CMO:0000004)108051528791230079Rat
631554Bp133Blood pressure QTL 1330.005arterial blood pressure trait (VT:2000000)systolic blood pressure (CMO:0000004)1074336463851208Rat

1 to 10 of 184 rows


Database
Acc Id
Source(s)
NCBI Gene Bp87

Note Type Note Reference
qtl_cross_type intercross  
qtl_general associates with increased blood pressures than that of the WKY 619634
qtl_general becomes a major determinant of blood pressure after 7 months of salt loading; the LOD score reduced to 3.2 while other three QTLs completely lost linkage 619634