Bp299 QTL Report (Rattus norvegicus) - Rat Genome Database
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QTL: Bp299 (Blood pressure QTL 299) Rattus norvegicus

Symbol: Bp299
Name: Blood pressure QTL 299
RGD ID: 1642290
Also known as: S.LEW BP QTL1
Trait: arterial blood pressure trait   (VT:2000000)    
Measurement Type: systolic blood pressure   (CMO:0000004)    
LOD Score: Not Available
P Value: Not Available
Variance: Not Available
Position
Rat AssemblyChrPosition (strand)SourceJBrowse
Rnor_6.01070,647,089 - 71,727,943RGD_MAPPER_PIPELINERnor6.0
Rnor_5.01070,280,918 - 71,638,303RGDRnor5.0
RGSC_v3.41071,513,116 - 72,685,167RGDRGSC3.4
Cross Type: intercross
Strains Crossed: SS.LEW-(D10Mco84-D10Got93)/Mco 
JBrowse: View Region in Genome Browser (JBrowse)
Model



Candidate Gene Status
Ccl5 is a candidate Gene for Bp299
Ddx52 is a candidate Gene for Bp299

Experimental Data Annotations     Click to see Annotation Detail View

Clinical Measurement

Experimental Condition

Measurement Method

Vertebrate Trait

Rat Strain

References

References - curated
1. Saad Y, etal., Genomics. 2007 Jan 9;.
2. Saad Y, etal., Hypertension. 2007 Sep 24;.
Related QTLs

Related QTL Description Reference
Bp301 sub_region RGD:1642602
Bp300 sub_region RGD:1642602
Bp302 sub_region RGD:1642602


Region

Genes in Region
The following Genes overlap with this region.    Full Report CSV TAB Printer Analysis Tools
RGD IDSymbolNameChrStartStopSpecies
3647Ccl3C-C motif chemokine ligand 3107086951670871066Rat
69069Ccl5C-C motif chemokine ligand 5107073976470744303Rat
620684Synrgsynergin, gamma107127869871357791Rat
619957Wfdc18WAP four-disulfide core domain 18107100870971010863Rat
620441Ccl4C-C motif chemokine ligand 4107087092670886357Rat
621743Ddx52DExD-box helicase 52107125366771276397Rat
1303147Wfdc21WAP four-disulfide core domain 21107104732671053195Rat
1303200Ccl6chemokine (C-C motif) ligand 6107079811870802750Rat
621248Acacaacetyl-CoA carboxylase alpha107151939271719910Rat
1307415Dusp14dual specificity phosphatase 14107136368871383602Rat
3830Hnf1bHNF1 homeobox B107115986371218902Rat
1311573Mmp28matrix metallopeptidase 28107066069170681672Rat
1309959Tada2atranscriptional adaptor 2A107139370171441435Rat
1310563Ccl9chemokine (C-C motif) ligand 9107078342670788372Rat
1309595Taf15TATA-box binding protein associated factor 15107068986370721892Rat
1559875Heatr9HEAT repeat containing 9107072606870736707Rat
1566204Heatr6HEAT repeat containing 6107105434471083229Rat
1597447LOC689039hypothetical protein LOC689039107065584270659380Rat
2318090LOC100362498extracellular peptidase inhibitor-like107101355471014426Rat
6502228LOC100909660extracellular peptidase inhibitor-like107096439670966543Rat
7517962LOC102552988uncharacterized LOC102552988107146216871493312Rat
7502825Ac1576uncharacterized LOC102552783107134203571358887Rat
7632735LOC10255288640S ribosomal protein S15a-like107137923771379694Rat
7688718LOC102555300uncharacterized LOC102555300107102816471033059Rat
9277126LOC103693405uncharacterized LOC103693405107076662270775207Rat
9290621LOC103693406uncharacterized LOC103693406107079044070802668Rat
9379147LOC103695128WAP four-disulfide core domain protein 18-like107092639470928204Rat
11460333LOC10835211560S ribosomal protein L30-like107079484470795389Rat

Markers in Region
The following Markers overlap with this region.    Full Report CSV TAB Printer Gviewer
RGD IDSymbolExpected SizeChrStartStopSpeciesMatch
40444D10Rat220128107131527271315397Ratregion
44761D10Got88170107080006970800238Ratregion
44762D10Got97221107098826070988480Ratregion
44762D10Got97221107095698570957173Ratregion
44764D10Got90212107172636371726574Ratregion
625836D10Got161219107126407371264291Ratregion
62436D10Uia4186107098253570982716Ratregion
66377D7Uia4202107115577371156614Ratregion
1578857D10Chm150219107073749770737715Ratregion
1578862D10Chm149230107071817070718399Ratregion
1631382D10Got241126107098830170988458Ratregion
1631382D10Got241126107095702670957151Ratregion
1578903D10Chm184240107074506270745301Ratregion
1578910D10Chm122196107126110971261304Ratregion
1579042D10Chm185227107085981970860045Ratregion
1579047D10Chm152313107087366170873973Ratregion
1579156D10Chm151197107084583070846026Ratregion
1642081D10Mco89170107172777471727943Ratregion
1642083D10Mco88218107064708970647306Ratregion
1639949D10Got410184107105061471050799Ratregion
7206390Tcf2193107117049971170691Ratregion
5034776AI232002152107108329971083450Ratregion
5029415Tcf2472107115945171159922Ratregion
5027433AI32380497107086978470869880Ratregion
5025724RH129414191107073984670740036Ratregion
5051511AI987804135107121875071218884Ratregion
5049962RH133782206107088606670886271Ratregion
5050750RH134237201107132525171325451Ratregion
5041028RH128621186107079716370797348Ratregion
5044454RH130612183107127605671276238Ratregion
5047602RH132422182107065909470659275Ratregion
5048928RH133187180107145911071459289Ratregion
5041184RH128710214107079771070797923Ratregion
5075810RH138810121107066525070665370Ratregion
5077454RH139765200107139378971393988Ratregion
5077686RH139899195107136078171360975Ratregion
5079834RH141230200107121820371218402Ratregion
5078872RH140600220107127758771277806Ratregion
5073754RH137619232107126853471268765Ratregion
5068164AU047310202107098822770988428Ratregion
5068164AU047310202107095695270957122Ratregion
5069542AU046428210107140957371409777Ratregion
5083917AI175043226107065830070658525Ratregion
5502671Dusp14193107136462871364820Ratregion
5506268D17S610694107145744971458142Ratregion
5500161D11Mit97646107081205270812697Ratregion
5503636UniSTS:46541199107116485071164948Ratregion
5501490D17S1255110107157574471575853Ratregion
Position Markers

Flank 1: (D10Mco88)
Rat AssemblyChrPosition (strand)Source
Rnor_6.01070,647,089 - 70,647,306NCBI
Rnor_5.01071,109,113 - 71,109,330UniSTS
Rnor_5.01070,280,918 - 70,281,135UniSTS
RGSC_v3.41071,513,116 - 71,513,333UniSTS
Celera1067,171,651 - 67,171,868UniSTS
Cytogenetic Map10q26UniSTS
Flank 2: (D10Mco89)
Rat AssemblyChrPosition (strand)Source
Rnor_6.01071,727,774 - 71,727,943NCBI
Rnor_5.01071,638,135 - 71,638,303UniSTS
RGSC_v3.41072,684,998 - 72,685,167UniSTS
Celera1068,209,299 - 68,209,468UniSTS
Cytogenetic Map10 RGD


QTLs in Region (Rnor_6.0)
The following QTLs overlap with this region.    Full Report CSV TAB Printer Gviewer
RGD IDSymbolNameLODP ValueTraitSub TraitChrStartStopSpecies
8662860Vetf10Vascular elastic tissue fragility QTL 10artery integrity trait (VT:0010639)number of ruptures of the internal elastic lamina of the abdominal aorta and iliac arteries (CMO:0002562)10622909575983805Rat
61427Cia16Collagen induced arthritis QTL 163.2joint integrity trait (VT:0010548)joint inflammation composite score (CMO:0000919)10642907599492409Rat
2303118Mamtr7Mammary tumor resistance QTL 70.003mammary gland integrity trait (VT:0010552)mammary tumor growth rate (CMO:0000344)109841807108540162Rat
2301967Cm73Cardiac mass QTL 734.55heart left ventricle mass (VT:0007031)heart left ventricle weight to body weight ratio (CMO:0000530)101482789492423564Rat
631268Cia21Collagen induced arthritis QTL 213.1joint integrity trait (VT:0010548)joint inflammation composite score (CMO:0000919)1014827894107857673Rat
2316949Gluco60Glucose level QTL 603.7blood glucose amount (VT:0000188)blood glucose level (CMO:0000046)1014827894110992275Rat
1554317Bmd4Bone mineral density QTL 49.40.0001lumbar vertebra mineral mass (VT:0010511)volumetric bone mineral density (CMO:0001553)1020170031102897474Rat
70223Bp57Blood pressure QTL 575arterial blood pressure trait (VT:2000000)systolic blood pressure (CMO:0000004)102152390683549467Rat
70188BpQTLcluster1Blood pressure QTL cluster 14.864arterial blood pressure trait (VT:2000000)diastolic blood pressure (CMO:0000005)12152390690312401Rat
70188BpQTLcluster1Blood pressure QTL cluster 14.864arterial blood pressure trait (VT:2000000)systolic blood pressure (CMO:0000004)12152390690312401Rat
70188BpQTLcluster1Blood pressure QTL cluster 14.864arterial blood pressure trait (VT:2000000)mean arterial blood pressure (CMO:0000009)12152390690312401Rat
70188BpQTLcluster1Blood pressure QTL cluster 14.864arterial blood pressure trait (VT:2000000)pulse pressure (CMO:0000292)12152390690312401Rat
70198BpQTLcluster9Blood pressure QTL cluster 92.94arterial blood pressure trait (VT:2000000)mean arterial blood pressure (CMO:0000009)102152390690312401Rat
724556Pur2Proteinuria QTL 25.5urine protein amount (VT:0005160)urine protein level (CMO:0000591)102290149793886300Rat
1331791Cm31Cardiac mass QTL 313.84606heart mass (VT:0007028)heart wet weight (CMO:0000069)1023861015112626471Rat
631267Cia20Collagen induced arthritis QTL 203.2joint integrity trait (VT:0010548)joint inflammation composite score (CMO:0000919)1024483076107857673Rat
61325Aia5Adjuvant induced arthritis QTL 50.01joint integrity trait (VT:0010548)joint inflammation composite score (CMO:0000919)1024483076107857673Rat
61354Pia10Pristane induced arthritis QTL 100.01joint integrity trait (VT:0010548)joint inflammation composite score (CMO:0000919)1024483076107857673Rat
1298069Bp168Blood pressure QTL 1685.5blood pressure trait (VT:0000183)systolic blood pressure (CMO:0000004)1027237530101482600Rat
631542Bp82Blood pressure QTL 826.8arterial blood pressure trait (VT:2000000)systolic blood pressure (CMO:0000004)1027237530102427718Rat
2300171Bmd58Bone mineral density QTL 584.90.0001lumbar vertebra mineral mass (VT:0010511)volumetric bone mineral density (CMO:0001553)102878928073789280Rat
2292441Bp308Blood pressure QTL 308arterial blood pressure trait (VT:2000000)mean arterial blood pressure (CMO:0000009)103009990975099909Rat
10402859Bp381Blood pressure QTL 3810.002arterial blood pressure trait (VT:2000000)mean arterial blood pressure (CMO:0000009)103009990975099909Rat
724527Bp148Blood pressure QTL 1480.0001arterial blood pressure trait (VT:2000000)mean arterial blood pressure (CMO:0000009)103098380575983805Rat
1576311Pia26Pristane induced arthritis QTL 26joint integrity trait (VT:0010548)joint inflammation composite score (CMO:0000919)103191939778343192Rat
1578779Tcas10Tongue tumor susceptibility QTL 103.12tongue integrity trait (VT:0010553)number of squamous cell tumors of the tongue with diameter greater than 3 mm (CMO:0001950)103317903078179030Rat
631557Bp136Blood pressure QTL 1360.003arterial blood pressure trait (VT:2000000)systolic blood pressure (CMO:0000004)103334319278343192Rat
1576319Cia29Collagen induced arthritis QTL 29joint integrity trait (VT:0010548)joint inflammation composite score (CMO:0000919)103513942480139424Rat
6893342Cm78Cardiac mass QTL 780.10.88heart mass (VT:0007028)heart weight to body weight ratio (CMO:0000074)103618592982675365Rat
631552Vetf2Vascular elastic tissue fragility QTL 24.50.0002aorta elastic tissue integrity trait (VT:0010556)artery internal elastic lamina non-tumorous lesion count (CMO:0001913)103618592995845311Rat
2317042Aia20Adjuvant induced arthritis QTL 203.38joint integrity trait (VT:0010548)right rear ankle joint diameter (CMO:0002150)104051404485514044Rat
2317043Aia7Adjuvant induced arthritis QTL 73.82joint integrity trait (VT:0010548)left rear ankle joint diameter (CMO:0002149)104051404485514044Rat
1576308Schws1Schwannoma susceptibility QTL 10.0041nervous system integrity trait (VT:0010566)percentage of study population developing trigeminal nerve neurilemmomas during a period of time (CMO:0002017)1041260363106105607Rat
631269Cia22Collagen induced arthritis QTL 228.9joint integrity trait (VT:0010548)joint inflammation composite score (CMO:0000919)1041260363107857673Rat
631270Cia23Collagen induced arthritis QTL 233.9joint integrity trait (VT:0010548)joint inflammation composite score (CMO:0000919)1041260363107857673Rat
8552805Bw145Body weight QTL 1452.2body mass (VT:0001259)change in body weight to body weight ratio (CMO:0002216)104318865981042642Rat
1298078Stresp5Stress response QTL 52.990.00025blood corticosterone amount (VT:0005345)plasma corticosterone level (CMO:0001173)1043289657108540162Rat
61463Bp12Blood pressure QTL 126.30.0001arterial blood pressure trait (VT:2000000)systolic blood pressure (CMO:0000004)104370495588704955Rat
2300218Hpcl2Hepatic cholesterol level QTL 2liver cholesterol amount (VT:0010498)liver cholesterol level (CMO:0001597)104659302198939209Rat
9589030Epfw9Epididymal fat weight QTL 919.240.001epididymal fat pad mass (VT:0010421)epididymal fat pad weight to body weight ratio (CMO:0000658)104684834691848346Rat
7411614Foco18Food consumption QTL 180.001eating behavior trait (VT:0001431)feed conversion ratio (CMO:0001312)104684834691848346Rat
8694173Bw149Body weight QTL 1494.380.001body mass (VT:0001259)body weight gain (CMO:0000420)104684834691848346Rat
631547Bp87Blood pressure QTL 874.5arterial blood pressure trait (VT:2000000)systolic blood pressure (CMO:0000004)105063833795638337Rat
2293652Bmd22Bone mineral density QTL 224.90.0001femur mineral mass (VT:0010011)total volumetric bone mineral density (CMO:0001728)105128920384596393Rat
2293669Bmd33Bone mineral density QTL 334.50.0001femur strength trait (VT:0010010)femoral neck polar moment of inertia (CMO:0001670)105128920384596393Rat
2293679Bmd30Bone mineral density QTL 303.50.0001femur mineral mass (VT:0010011)total volumetric bone mineral density (CMO:0001728)105128920384596393Rat
2293705Bmd25Bone mineral density QTL 257.10.0001femur mineral mass (VT:0010011)cortical volumetric bone mineral density (CMO:0001730)105128920384596393Rat
7207811Bmd90Bone mineral density QTL 905.2femur size trait (VT:1000369)femoral neck cross-sectional area (CMO:0001697)105128920384596393Rat
1549846Scl47Serum cholesterol level QTL 473.6blood cholesterol amount (VT:0000180)serum total cholesterol level (CMO:0000363)105310471898104718Rat
61387Bp1Blood pressure QTL 15.1arterial blood pressure trait (VT:2000000)systolic blood pressure (CMO:0000004)1053621375112626471Rat
61387Bp1Blood pressure QTL 15.1arterial blood pressure trait (VT:2000000)diastolic blood pressure (CMO:0000005)1053621375112626471Rat
631530Tls3T-lymphoma susceptibility QTL 300.0001thymus integrity trait (VT:0010555)percentage of study population developing T-cell lymphomas during a period of time (CMO:0001911)105362581598939209Rat
631535Cm51Cardiac mass QTL 513heart mass (VT:0007028)calculated heart weight (CMO:0000073)105363748594807701Rat
1359017Hrtrt21Heart rate QTL 212.4heart pumping trait (VT:2000009)heart rate (CMO:0000002)1055224855100224855Rat
70171Cari1Carrageenan-induced inflammation QTL 14.90.0005hypodermis integrity trait (VT:0010550)inflammatory exudate volume (CMO:0001429)1055678976112626471Rat
70164Bw21Body weight QTL 214.360.00005body mass (VT:0001259)body weight (CMO:0000012)1055679084102427604Rat
1354608Cm33Cardiac mass QTL 332.8heart left ventricle mass (VT:0007031)heart left ventricle wet weight (CMO:0000071)1056698730101698730Rat
1549831Bss6Bone structure and strength QTL 64lumbar vertebra strength trait (VT:0010574)vertebra ultimate force (CMO:0001678)1060450007105450007Rat
2312662Slep8Serum leptin concentration QTL 80.05blood leptin amount (VT:0005667)serum leptin level (CMO:0000780)1060875260105875260Rat
2312668Scl65Serum cholesterol level QTL 650.001blood cholesterol amount (VT:0000180)serum total cholesterol level (CMO:0000363)1060875260105875260Rat
2312672Insul15Insulin level QTL 150.01blood insulin amount (VT:0001560)serum insulin level (CMO:0000358)1060875260105875260Rat
2293698Bss43Bone structure and strength QTL 435.330.0001lumbar vertebra size trait (VT:0010518)lumbar vertebra cross-sectional area (CMO:0001689)1062096293107096293Rat
70363Bp71Blood pressure QTL 710.04arterial blood pressure trait (VT:2000000)mean arterial blood pressure (CMO:0000009)106464817584601269Rat
2306970Anxrr22Anxiety related response QTL 225.95fear/anxiety-related behavior trait (VT:1000241)number of periods of voluntary immobility (CMO:0001045)1064648175101691360Rat
1558643Cm44Cardiac mass QTL 444.80.0000368heart mass (VT:0007028)heart wet weight (CMO:0000069)1064648175102149713Rat
6893336Cm75Cardiac mass QTL 750.10.87heart mass (VT:0007028)heart weight to body weight ratio (CMO:0000074)1064648175102149713Rat
61402Niddm3Non-insulin dependent diabetes mellitus QTL 34.58blood glucose amount (VT:0000188)blood glucose level (CMO:0000046)106464831185513822Rat
61449Ciaa2CIA Autoantibody QTL 27.1blood autoantibody amount (VT:0003725)calculated serum anti-type 2 collagen antibody titer (CMO:0001279)1065590122110590122Rat
2313103Bss80Bone structure and strength QTL 8020.0001tibia strength trait (VT:1000284)tibia midshaft endosteal cross-sectional area (CMO:0001716)1065992275110992275Rat
2313105Bss79Bone structure and strength QTL 791.80.0001tibia size trait (VT:0100001)tibia midshaft cross-sectional area (CMO:0001717)1065992275110992275Rat
7387312Bw125Body weight QTL 12530.0047retroperitoneal fat pad mass (VT:0010430)retroperitoneal fat pad weight (CMO:0000356)1067880046112626471Rat
1581559Eae18Experimental allergic encephalomyelitis QTL 180.00002nervous system integrity trait (VT:0010566)experimental autoimmune encephalomyelitis severity score (CMO:0001419)1067988218110992091Rat
2298481Eau9Experimental allergic uveoretinitis QTL 90.0169uvea integrity trait (VT:0010551)experimental autoimmune uveitis score (CMO:0001504)106830503785514044Rat
1357344Bp249Blood pressure QTL 2490.0001arterial blood pressure trait (VT:2000000)systolic blood pressure (CMO:0000004)1069123603101482600Rat
631565Hcuc4Hepatic copper content QTL 44.15hepatic copper amount (VT:0003065)liver copper weight to liver dry weight ratio (CMO:0001512)106934845975983662Rat
2317029Aia19Adjuvant induced arthritis QTL 192.98joint integrity trait (VT:0010548)left rear ankle joint diameter (CMO:0002149)1069385595112626471Rat
2317039Aia6Adjuvant induced arthritis QTL 64.31joint integrity trait (VT:0010548)right rear ankle joint diameter (CMO:0002150)1069385595112626471Rat
2289985Bp305Blood pressure QTL 305arterial blood pressure trait (VT:2000000)systolic blood pressure (CMO:0000004)106991083276109716Rat
10450498Bp384Blood pressure QTL 3840.002arterial blood pressure trait (VT:2000000)mean arterial blood pressure (CMO:0000009)1070166960112626471Rat
1642290Bp299Blood pressure QTL 299arterial blood pressure trait (VT:2000000)systolic blood pressure (CMO:0000004)107064708971727943Rat
1642980Bp300Blood pressure QTL 300arterial blood pressure trait (VT:2000000)systolic blood pressure (CMO:0000004)1070800069112626471Rat
61396Bp9Blood pressure QTL 94.80.0001arterial blood pressure trait (VT:2000000)systolic blood pressure (CMO:0000004)1071692298112626471Rat


Additional Information

RGD Curation Notes
Note Type Note Reference
qtl_cross_type intercross  
qtl_general number of animals used: 20 congenics and 20 SS/Jr as control 1599269
qtl_general this QTL contains 18 genes none of which play a role in blood pressure control hence this region holds potential genetic factors that control blood pressure 1599269
qtl_general gender: male 1599269
qtl_general details of the measurement method: systolic blood pressure was measured by the tail-cuff method at 40-42 days of age for 4 days once a day and the average of three readings taken as Bp value 1599269