Gene: Traf4 (Tnf receptor associated factor 4) Rattus norvegicus
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Symbol: Traf4
Name: Tnf receptor associated factor 4
Description: ENCODES a protein that exhibits identical protein binding (ortholog); protein kinase binding (ortholog); thioesterase binding (ortholog); INVOLVED IN positive regulation of JNK cascade (ortholog); positive regulation of protein homodimerization activity (ortholog); positive regulation of protein kinase activity (ortholog); PARTICIPATES IN small cell lung carcinoma pathway; ASSOCIATED WITH Brain Injuries (ortholog); FOUND IN cytoplasm (ortholog); nucleus (ortholog); INTERACTS WITH 1,1,1-Trichloro-2-(o-chlorophenyl)-2-(p-chlorophenyl)ethane; 1-chloro-2-[2,2-dichloro-1-(4-chlorophenyl)ethyl]benzene; 2,3,7,8-tetrachlorodibenzodioxine
AGR Description: Predicted to have several functions, including WW domain binding activity, enzyme binding activity, and identical protein binding activity; predicted to be involved in several processes, including positive regulation of cellular metabolic process, positive regulation of protein homodimerization activity, and respiratory gaseous exchange; predicted to localize to the cytoplasm, nucleus, and protein-containing complex; orthologous to human TRAF4 (TNF receptor associated factor 4).
Merged Description: Predicted to have several functions, including WW domain binding activity, enzyme binding activity, and identical protein binding activity; predicted to be involved in several processes, including positive regulation of cellular metabolic process, positive regulation of protein homodimerization activity, and respiratory gaseous exchange; predicted to localize to the cytoplasm, nucleus, and protein-containing complex; orthologous to human TRAF4 (TNF receptor associated factor 4); PARTICIPATES IN small cell lung carcinoma pathway; INTERACTS WITH 1,1,1-Trichloro-2-(o-chlorophenyl)-2-(p-chlorophenyl)ethane; 1-chloro-2-[2,2-dichloro-1-(4-chlorophenyl)ethyl]benzene; 2,3,7,8-tetrachlorodibenzodioxine.
Type: protein-coding
RefSeq Status: PROVISIONAL
Also known as: LOC303285; TNF receptor-associated factor 4
Orthologs:
Homo sapiens (human) : TRAF4 (TNF receptor associated factor 4)  HGNC  Alliance
Mus musculus (house mouse) : Traf4 (TNF receptor associated factor 4)  MGI  Alliance
Chinchilla lanigera (long-tailed chinchilla) : Traf4 (TNF receptor associated factor 4)
Pan paniscus (bonobo/pygmy chimpanzee) : TRAF4 (TNF receptor associated factor 4)
Canis lupus familiaris (dog) : TRAF4 (TNF receptor associated factor 4)
Ictidomys tridecemlineatus (thirteen-lined ground squirrel) : Traf4 (TNF receptor associated factor 4)
Sus scrofa (pig) : TRAF4 (TNF receptor associated factor 4)
more info ...
Latest Assembly: Rnor_6.0 - RGSC Genome Assembly v6.0
Position:
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Rnor_6.01065,418,688 - 65,424,802 (-)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_5.01066,209,815 - 66,215,919 (+)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.41064,471,018 - 64,477,122 (+)NCBIRGSC3.4rn4RGSC3.4
RGSC_v3.11064,484,719 - 64,490,231 (+)NCBI
Celera1062,031,830 - 62,037,936 (-)NCBICelera
Cytogenetic Map10q25NCBI
JBrowse: View Region in Genome Browser (JBrowse)
Model


Disease Annotations
Gene-Chemical Interaction Annotations
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Molecular Pathway Annotations
References - curated
References - uncurated
RGD Disease Portals

Genomics

Comparative Map Data
Position Markers
QTLs in Region (Rnor_6.0)
miRNA Target Status

Sequence

Nucleotide Sequences
Protein Sequences
Transcriptome
Promoters

Strain Variation

Strain Sequence Variants (Rnor 5.0)

Additional Information

External Database Links
Nomenclature History
 
More on Traf4
Alliance Gene
NCBI Gene
Ensembl Gene
JBrowse: rn5 rn6
NCBI Genome Data Viewer

RGD Object Information
RGD ID: 1306708
Created: 2005-01-12
Species: Rattus norvegicus
Last Modified: 2019-04-12
Status: ACTIVE



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RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.