Myh2 (myosin heavy chain 2) - Rat Genome Database

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Gene: Myh2 (myosin heavy chain 2) Rattus norvegicus
Analyze
Symbol: Myh2
Name: myosin heavy chain 2
RGD ID: 620354
Description: Predicted to enable ATP binding activity; actin filament binding activity; and cytoskeletal motor activity. Predicted to be involved in muscle contraction. Predicted to act upstream of or within actin-mediated cell contraction; plasma membrane repair; and response to activity. Predicted to be located in several cellular components, including A band; Golgi apparatus; and actomyosin contractile ring. Predicted to be part of protein-containing complex. Human ortholog(s) of this gene implicated in congenital myopathy 6 and inclusion body myositis. Orthologous to human MYH2 (myosin heavy chain 2); PARTICIPATES IN myocarditis pathway; INTERACTS WITH 17beta-estradiol; ammonium chloride; benzo[a]pyrene.
Type: protein-coding
RefSeq Status: VALIDATED
Previously known as: 2A myosin heavy chain; Myh1; Myh2a; MyHC-2A; MyHC-IIA; myosin heavy chain IIa; myosin heavy chain type IIx; myosin, heavy chain 2, skeletal muscle, adult; myosin, heavy polypeptide 2, skeletal muscle, adult; myosin-2
RGD Orthologs
Human
Mouse
Chinchilla
Bonobo
Squirrel
Green Monkey
Naked Mole-Rat
Alliance Genes
More Info more info ...
Latest Assembly: mRatBN7.2 - mRatBN7.2 Assembly
Position:
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr81052,355,739 - 52,382,235 (+)NCBIGRCr8
mRatBN7.21051,856,738 - 51,883,236 (+)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl1051,856,738 - 51,883,236 (+)EnsemblmRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx1056,513,601 - 56,540,116 (+)NCBIRnor_SHRUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.01056,002,605 - 56,029,121 (+)NCBIRnor_SHRSPUTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.01051,512,962 - 51,539,508 (+)NCBIRnor_WKYUTH_Rnor_WKY_Bbb_1.0
Rnor_6.01053,711,895 - 53,738,164 (+)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl1053,713,938 - 53,848,347 (+)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.01053,465,051 - 53,491,320 (+)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.41053,864,777 - 53,891,711 (+)NCBIRGSC3.4RGSC_v3.4rn4RGSC3.4
Celera1051,039,592 - 51,066,088 (+)NCBICelera
Cytogenetic Map10q24NCBI
JBrowse: View Region in Genome Browser (JBrowse)
Model


Disease Annotations     Click to see Annotation Detail View

Gene Ontology Annotations     Click to see Annotation Detail View

Biological Process

Cellular Component

Molecular Function

Molecular Pathway Annotations     Click to see Annotation Detail View
References

References - curated
# Reference Title Reference Citation
1. Type 2X-myosin heavy chain is coded by a muscle fiber type-specific and developmentally regulated gene. DeNardi C, etal., J Cell Biol 1993 Nov;123(4):823-35.
2. Cloning and in situ hybridization of type 2A and 2B rat skeletal muscle myosin tail region: implications for filament assembly. Lieber RL, etal., Biochem Biophys Res Commun 1993 Dec 30;197(3):1312-8.
3. Autosomal dominant myopathy: missense mutation (Glu-706 --> Lys) in the myosin heavy chain IIa gene. Martinsson T, etal., Proc Natl Acad Sci U S A. 2000 Dec 19;97(26):14614-9.
4. Electronic Transfer of LocusLink and RefSeq Data NCBI rat LocusLink and RefSeq merged data July 26, 2002
5. OMIM Disease Annotation Pipeline OMIM Disease Annotation Pipeline
6. KEGG Annotation Import Pipeline Pipeline to import KEGG annotations from KEGG into RGD
7. GOA pipeline RGD automated data pipeline
8. ClinVar Automated Import and Annotation Pipeline RGD automated import pipeline for ClinVar variants, variant-to-disease annotations and gene-to-disease annotations
9. Data Import for Chemical-Gene Interactions RGD automated import pipeline for gene-chemical interactions
10. Comprehensive gene review and curation RGD comprehensive gene curation
11. Mutations and sequence variation in the human myosin heavy chain IIa gene (MYH2). Tajsharghi H, etal., Eur J Hum Genet 2005 Mar 2;.
12. Myosin heavy chain isoform mRNA and protein levels after long-term paralysis. Talmadge RJ, etal., Biochem Biophys Res Commun 2004 Dec 3;325(1):296-301.
13. Myosin IIA drives neurite retraction. Wylie SR and Chantler PD, Mol Biol Cell 2003 Nov;14(11):4654-66. Epub 2003 Sep 5.
Additional References at PubMed
PMID:8145163   PMID:14617807   PMID:15548599   PMID:17030512   PMID:18310078   PMID:18495866   PMID:18761673   PMID:19040707   PMID:19260067   PMID:19369448   PMID:19738937   PMID:20064569  
PMID:20713983   PMID:21306737   PMID:21518265   PMID:21884692   PMID:22206666   PMID:22427691   PMID:22750946   PMID:23793062   PMID:24465547   PMID:25753039   PMID:33573052   PMID:35352799  


Genomics

Comparative Map Data
Myh2
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr81052,355,739 - 52,382,235 (+)NCBIGRCr8
mRatBN7.21051,856,738 - 51,883,236 (+)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl1051,856,738 - 51,883,236 (+)EnsemblmRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx1056,513,601 - 56,540,116 (+)NCBIRnor_SHRUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.01056,002,605 - 56,029,121 (+)NCBIRnor_SHRSPUTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.01051,512,962 - 51,539,508 (+)NCBIRnor_WKYUTH_Rnor_WKY_Bbb_1.0
Rnor_6.01053,711,895 - 53,738,164 (+)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl1053,713,938 - 53,848,347 (+)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.01053,465,051 - 53,491,320 (+)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.41053,864,777 - 53,891,711 (+)NCBIRGSC3.4RGSC_v3.4rn4RGSC3.4
Celera1051,039,592 - 51,066,088 (+)NCBICelera
Cytogenetic Map10q24NCBI
MYH2
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh381710,521,148 - 10,549,658 (-)NCBIGRCh38GRCh38hg38GRCh38
GRCh38.p14 Ensembl1710,521,148 - 10,549,700 (-)EnsemblGRCh38hg38GRCh38
GRCh371710,424,465 - 10,452,975 (-)NCBIGRCh37GRCh37hg19GRCh37
Build 361710,365,190 - 10,393,742 (-)NCBINCBI36Build 36hg18NCBI36
Build 341710,365,193 - 10,393,700NCBI
Celera1710,455,328 - 10,483,875 (-)NCBICelera
Cytogenetic Map17p13.1NCBI
HuRef1710,324,058 - 10,352,633 (-)NCBIHuRef
CHM1_11710,434,312 - 10,462,875 (-)NCBICHM1_1
T2T-CHM13v2.01710,428,658 - 10,457,214 (-)NCBIT2T-CHM13v2.0
Myh2
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm391167,061,853 - 67,088,343 (+)NCBIGRCm39GRCm39mm39
GRCm39 Ensembl1167,061,853 - 67,088,343 (+)EnsemblGRCm39 Ensembl
GRCm381167,171,027 - 67,197,517 (+)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl1167,171,027 - 67,197,517 (+)EnsemblGRCm38mm10GRCm38
MGSCv371166,984,529 - 67,011,019 (+)NCBIGRCm37MGSCv37mm9NCBIm37
MGSCv361166,987,415 - 67,013,709 (+)NCBIMGSCv36mm8
Celera1174,109,947 - 74,136,336 (+)NCBICelera
Cytogenetic Map11B3NCBI
cM Map1140.59NCBI
Myh2
(Chinchilla lanigera - long-tailed chinchilla)
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0NW_0049554676,655,346 - 6,681,354 (+)NCBIChiLan1.0ChiLan1.0
MYH2
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
NHGRI_mPanPan1-v21963,199,518 - 63,228,069 (+)NCBINHGRI_mPanPan1-v2
NHGRI_mPanPan11768,010,300 - 68,038,614 (+)NCBINHGRI_mPanPan1
Mhudiblu_PPA_v01741,103,730 - 41,132,264 (+)NCBIMhudiblu_PPA_v0Mhudiblu_PPA_v0panPan3
PanPan1.11745,851,160 - 45,879,666 (+)NCBIpanpan1.1PanPan1.1panPan2
PanPan1.1 Ensembl1745,851,160 - 45,879,666 (+)Ensemblpanpan1.1panPan2
Myh2
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
SpeTri2.0NW_0049365953,391,179 - 3,398,610 (-)NCBISpeTri2.0SpeTri2.0SpeTri2.0
LOC103242383
(Chlorocebus sabaeus - green monkey)
Green Monkey AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.1169,863,336 - 9,891,271 (-)NCBIChlSab1.1ChlSab1.1chlSab2
Vero_WHO_p1.0NW_02366605911,451,769 - 11,479,024 (+)NCBIVero_WHO_p1.0Vero_WHO_p1.0
Myh2
(Heterocephalus glaber - naked mole-rat)
Naked Mole-Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla 1.0NW_00462478612,888,622 - 12,914,886 (-)NCBIHetGla_female_1.0HetGla 1.0hetGla2

Variants

.
Variants in Myh2
165 total Variants

QTLs in Region (mRatBN7.2)
The following QTLs overlap with this region.    Full Report CSV TAB Printer Gviewer
RGD IDSymbolNameLODP ValueTraitSub TraitChrStartStopSpecies
70223Bp57Blood pressure QTL 575arterial blood pressure trait (VT:2000000)systolic blood pressure (CMO:0000004)10180676123Rat
631554Bp133Blood pressure QTL 1330.005arterial blood pressure trait (VT:2000000)systolic blood pressure (CMO:0000004)1074336463851208Rat
2298544Neuinf9Neuroinflammation QTL 94.6nervous system integrity trait (VT:0010566)spinal cord complement component 1, q subcomponent, B chain mRNA level (CMO:0002126)10580199062146030Rat
8662860Vetf10Vascular elastic tissue fragility QTL 10artery integrity trait (VT:0010639)number of ruptures of the internal elastic lamina of the abdominal aorta and iliac arteries (CMO:0002562)10615418273453136Rat
61427Cia16Collagen induced arthritis QTL 163.2joint integrity trait (VT:0010548)joint inflammation composite score (CMO:0000919)10635789696121100Rat
2303118Mamtr7Mammary tumor resistance QTL 70.003mammary gland integrity trait (VT:0010552)mammary tumor growth rate (CMO:0000344)109658275104670812Rat
9590310Scort19Serum corticosterone level QTL 196.30.001blood corticosterone amount (VT:0005345)plasma corticosterone level (CMO:0001173)101147401056474010Rat
9590268Scort13Serum corticosterone level QTL 133.260.001blood corticosterone amount (VT:0005345)plasma corticosterone level (CMO:0001173)101147401056474010Rat
9589136Insul27Insulin level QTL 2710.460.001blood insulin amount (VT:0001560)plasma insulin level (CMO:0000342)101147401056474010Rat
2301967Cm73Cardiac mass QTL 734.55heart left ventricle mass (VT:0007031)heart left ventricle weight to body weight ratio (CMO:0000530)101448701189062041Rat
631268Cia21Collagen induced arthritis QTL 213.1joint integrity trait (VT:0010548)joint inflammation composite score (CMO:0000919)1014487011104060283Rat
2316949Gluco60Glucose level QTL 603.7blood glucose amount (VT:0000188)blood glucose level (CMO:0000046)1014487011107057807Rat
1354587Kidm21Kidney mass QTL 213.3kidney mass (VT:0002707)right kidney wet weight (CMO:0000082)101502851360430477Rat
631564Apr3Acute phase response QTL 33.9blood interleukin-6 amount (VT:0008595)plasma interleukin-6 level (CMO:0001927)101527595560275955Rat
6893350Bw99Body weight QTL 990.870.16body mass (VT:0001259)body weight (CMO:0000012)11590666560906665Rat
6893352Bw100Body weight QTL 1000.330.6body mass (VT:0001259)body weight (CMO:0000012)11590666560906665Rat
1598852Anxrr19Anxiety related response QTL 195.07body movement coordination trait (VT:0005424)number of rearing movements in an experimental apparatus (CMO:0001752)101816784163167841Rat
2313055Bw96Body weight QTL 963.60.0001body mass (VT:0001259)body weight (CMO:0000012)101960648364606483Rat
2313087Bmd80Bone mineral density QTL 803.20.0001tibia mineral mass (VT:1000283)total volumetric bone mineral density (CMO:0001728)101960648364606483Rat
1554317Bmd4Bone mineral density QTL 49.40.0001lumbar vertebra mineral mass (VT:0010511)volumetric bone mineral density (CMO:0001553)101981604299406971Rat
1581497Esta1Estrogen-induced thymic atrophy QTL 1thymus mass (VT:0004954)thymus wet weight (CMO:0000855)102132980561345413Rat
724556Pur2Proteinuria QTL 25.5urine protein amount (VT:0005160)urine protein level (CMO:0000591)102242750090627625Rat
61354Pia10Pristane induced arthritis QTL 100.01joint integrity trait (VT:0010548)joint inflammation composite score (CMO:0000919)1023444813104060283Rat
631267Cia20Collagen induced arthritis QTL 203.2joint integrity trait (VT:0010548)joint inflammation composite score (CMO:0000919)1023444813104060283Rat
61325Aia5Adjuvant induced arthritis QTL 50.01joint integrity trait (VT:0010548)joint inflammation composite score (CMO:0000919)1023444813104060283Rat
70224Eae3Experimental allergic encephalomyelitis QTL 34.1nervous system integrity trait (VT:0010566)experimental autoimmune encephalomyelitis incidence/prevalence measurement (CMO:0001046)102652195761345413Rat
1298069Bp168Blood pressure QTL 1685.5blood pressure trait (VT:0000183)systolic blood pressure (CMO:0000004)102652195798003205Rat
631542Bp82Blood pressure QTL 826.8arterial blood pressure trait (VT:2000000)systolic blood pressure (CMO:0000004)102652195798952741Rat
2300171Bmd58Bone mineral density QTL 584.90.0001lumbar vertebra mineral mass (VT:0010511)volumetric bone mineral density (CMO:0001553)102694462871944628Rat
10402859Bp381Blood pressure QTL 3810.002arterial blood pressure trait (VT:2000000)mean arterial blood pressure (CMO:0000009)102760646872606468Rat
2292441Bp308Blood pressure QTL 308arterial blood pressure trait (VT:2000000)mean arterial blood pressure (CMO:0000009)102760646872606468Rat
724527Bp148Blood pressure QTL 1480.0001arterial blood pressure trait (VT:2000000)mean arterial blood pressure (CMO:0000009)102845313673453136Rat
1600371Mcs21Mammary carcinoma susceptibility QTL 213mammary gland integrity trait (VT:0010552)mammary tumor growth rate (CMO:0000344)102887565052200160Rat
1331762Rf40Renal function QTL 403.873kidney blood vessel physiology trait (VT:0100012)absolute change in renal vascular resistance (CMO:0001900)102929950464155584Rat
1331791Cm31Cardiac mass QTL 313.84606heart mass (VT:0007028)heart wet weight (CMO:0000069)1029299504107211142Rat
631557Bp136Blood pressure QTL 1360.003arterial blood pressure trait (VT:2000000)systolic blood pressure (CMO:0000004)103063205375632053Rat
1576311Pia26Pristane induced arthritis QTL 26joint integrity trait (VT:0010548)joint inflammation composite score (CMO:0000919)103122402675632053Rat
1578779Tcas10Tongue tumor susceptibility QTL 103.12tongue integrity trait (VT:0010553)number of squamous cell tumors of the tongue with diameter greater than 3 mm (CMO:0001950)103129743976297439Rat
1576319Cia29Collagen induced arthritis QTL 29joint integrity trait (VT:0010548)joint inflammation composite score (CMO:0000919)103397392178973921Rat
1358897Stresp6Stress response QTL 64.170.022blood norepinephrine amount (VT:0005663)plasma norepinephrine level (CMO:0001010)103539226764155584Rat
61441Btemp1Thermal response to stress QTL 14body temperature trait (VT:0005535)core body temperature (CMO:0001036)103539245763642539Rat
2317042Aia20Adjuvant induced arthritis QTL 203.38joint integrity trait (VT:0010548)right rear ankle joint diameter (CMO:0002150)103756507982565079Rat
2317043Aia7Adjuvant induced arthritis QTL 73.82joint integrity trait (VT:0010548)left rear ankle joint diameter (CMO:0002149)103756507982565079Rat
1576308Schws1Schwannoma susceptibility QTL 10.0041nervous system integrity trait (VT:0010566)percentage of study population developing trigeminal nerve neurilemmomas during a period of time (CMO:0002017)1040035094102359817Rat
631269Cia22Collagen induced arthritis QTL 228.9joint integrity trait (VT:0010548)joint inflammation composite score (CMO:0000919)1040035094104060283Rat
631270Cia23Collagen induced arthritis QTL 233.9joint integrity trait (VT:0010548)joint inflammation composite score (CMO:0000919)1040035094104060283Rat
631552Vetf2Vascular elastic tissue fragility QTL 24.50.0002aorta elastic tissue integrity trait (VT:0010556)artery internal elastic lamina non-tumorous lesion count (CMO:0001913)104114263386142633Rat
61463Bp12Blood pressure QTL 126.30.0001arterial blood pressure trait (VT:2000000)systolic blood pressure (CMO:0000004)104133325886333258Rat
8552805Bw145Body weight QTL 1452.2body mass (VT:0001259)change in body weight to body weight ratio (CMO:0002216)104194452678307017Rat
1298078Stresp5Stress response QTL 52.990.00025blood corticosterone amount (VT:0005345)plasma corticosterone level (CMO:0001173)1042045676104670812Rat
70188BpQTLcluster1Blood pressure QTL cluster 14.864arterial blood pressure trait (VT:2000000)diastolic blood pressure (CMO:0000005)14232313287323132Rat
70188BpQTLcluster1Blood pressure QTL cluster 14.864arterial blood pressure trait (VT:2000000)systolic blood pressure (CMO:0000004)14232313287323132Rat
70188BpQTLcluster1Blood pressure QTL cluster 14.864arterial blood pressure trait (VT:2000000)mean arterial blood pressure (CMO:0000009)14232313287323132Rat
70188BpQTLcluster1Blood pressure QTL cluster 14.864arterial blood pressure trait (VT:2000000)pulse pressure (CMO:0000292)14232313287323132Rat
70198BpQTLcluster9Blood pressure QTL cluster 92.94arterial blood pressure trait (VT:2000000)mean arterial blood pressure (CMO:0000009)104232313287323132Rat
6893342Cm78Cardiac mass QTL 780.10.88heart mass (VT:0007028)heart weight to body weight ratio (CMO:0000074)104287676679813922Rat
9589030Epfw9Epididymal fat weight QTL 919.240.001epididymal fat pad mass (VT:0010421)epididymal fat pad weight to body weight ratio (CMO:0000658)104444169989441699Rat
7411614Foco18Food consumption QTL 180.001eating behavior trait (VT:0001431)feed conversion ratio (CMO:0001312)104444169989441699Rat
8694173Bw149Body weight QTL 1494.380.001body mass (VT:0001259)body weight gain (CMO:0000420)104444169989441699Rat
2300218Hpcl2Hepatic cholesterol level QTL 2liver cholesterol amount (VT:0010498)liver cholesterol level (CMO:0001597)104502965095600334Rat
631547Bp87Blood pressure QTL 874.5arterial blood pressure trait (VT:2000000)systolic blood pressure (CMO:0000004)104736947092369470Rat
2293705Bmd25Bone mineral density QTL 257.10.0001femur mineral mass (VT:0010011)compact volumetric bone mineral density (CMO:0001730)104944455181709989Rat
7207811Bmd90Bone mineral density QTL 905.2femur size trait (VT:1000369)femoral neck cross-sectional area (CMO:0001697)104944455181709989Rat
2293652Bmd22Bone mineral density QTL 224.90.0001femur mineral mass (VT:0010011)total volumetric bone mineral density (CMO:0001728)104944455181709989Rat
2293669Bmd33Bone mineral density QTL 334.50.0001femur strength trait (VT:0010010)femoral neck polar moment of inertia (CMO:0001670)104944455181709989Rat
2293679Bmd30Bone mineral density QTL 303.50.0001femur mineral mass (VT:0010011)total volumetric bone mineral density (CMO:0001728)104944455181709989Rat
1549846Scl47Serum cholesterol level QTL 473.6blood cholesterol amount (VT:0000180)serum total cholesterol level (CMO:0000363)105057470795574707Rat
70364Bp72Blood pressure QTL 72arterial blood pressure trait (VT:2000000)mean arterial blood pressure (CMO:0000009)105112110096121100Rat
61387Bp1Blood pressure QTL 15.1arterial blood pressure trait (VT:2000000)systolic blood pressure (CMO:0000004)1051770177107211142Rat
61387Bp1Blood pressure QTL 15.1arterial blood pressure trait (VT:2000000)diastolic blood pressure (CMO:0000005)1051770177107211142Rat
1359017Hrtrt21Heart rate QTL 212.4heart pumping trait (VT:2000009)heart rate (CMO:0000002)105177294096772940Rat
631530Tls3T-lymphoma susceptibility QTL 300.0001thymus integrity trait (VT:0010555)percentage of study population developing T-cell lymphomas during a period of time (CMO:0001911)105177461295600334Rat
631535Cm51Cardiac mass QTL 513heart mass (VT:0007028)calculated heart weight (CMO:0000073)105178628291669536Rat

Markers in Region
RH94556  
Rat AssemblyChrPosition (strand)SourceJBrowse
mRatBN7.21051,883,108 - 51,883,189 (+)MAPPERmRatBN7.2
Rnor_6.01053,738,037 - 53,738,117NCBIRnor6.0
Rnor_5.01053,491,193 - 53,491,273UniSTSRnor5.0
RGSC_v3.41053,891,584 - 53,891,664UniSTSRGSC3.4
Celera1051,065,961 - 51,066,041UniSTS
RH 3.4 Map10571.9UniSTS
Cytogenetic Map10q24UniSTS


Expression


Sequence


RefSeq Acc Id: ENSRNOT00000004236   ⟹   ENSRNOP00000004236
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.2 Ensembl1051,856,738 - 51,883,236 (+)Ensembl
RefSeq Acc Id: ENSRNOT00000004295   ⟹   ENSRNOP00000004295
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.2 Ensembl1051,885,913 - 51,909,699 (+)Ensembl
RefSeq Acc Id: ENSRNOT00000045718   ⟹   ENSRNOP00000046362
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.2 Ensembl1051,923,355 - 51,946,295 (+)Ensembl
RefSeq Acc Id: ENSRNOT00000082871   ⟹   ENSRNOP00000072943
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.2 Ensembl1051,885,913 - 51,946,295 (+)Ensembl
RefSeq Acc Id: ENSRNOT00000085582   ⟹   ENSRNOP00000071998
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.2 Ensembl1051,885,913 - 51,909,699 (+)Ensembl
RefSeq Acc Id: ENSRNOT00000086599   ⟹   ENSRNOP00000071422
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.2 Ensembl1051,856,738 - 51,883,236 (+)Ensembl
RefSeq Acc Id: NM_001135157   ⟹   NP_001128629
RefSeq Status: VALIDATED
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr81052,355,739 - 52,382,235 (+)NCBI
mRatBN7.21051,856,738 - 51,883,236 (+)NCBI
Rnor_6.01053,711,895 - 53,738,164 (+)NCBI
Rnor_5.01053,465,051 - 53,491,320 (+)NCBI
RGSC_v3.41053,864,777 - 53,891,711 (+)RGD
Celera1051,039,592 - 51,066,088 (+)RGD
Sequence:
RefSeq Acc Id: XM_039086900   ⟹   XP_038942828
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr81052,355,804 - 52,382,233 (+)NCBI
mRatBN7.21051,856,799 - 51,883,236 (+)NCBI
RefSeq Acc Id: NP_001128629   ⟸   NM_001135157
- UniProtKB: A0A0G2K0F5 (UniProtKB/TrEMBL),   A6HFI0 (UniProtKB/TrEMBL),   G3V6E1 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: XP_038942828   ⟸   XM_039086900
- Peptide Label: isoform X1
- UniProtKB: A0A0G2K0F5 (UniProtKB/TrEMBL),   A6HFI0 (UniProtKB/TrEMBL),   G3V6E1 (UniProtKB/TrEMBL)
RefSeq Acc Id: ENSRNOP00000071422   ⟸   ENSRNOT00000086599
RefSeq Acc Id: ENSRNOP00000004236   ⟸   ENSRNOT00000004236
RefSeq Acc Id: ENSRNOP00000046362   ⟸   ENSRNOT00000045718
RefSeq Acc Id: ENSRNOP00000071998   ⟸   ENSRNOT00000085582
RefSeq Acc Id: ENSRNOP00000072943   ⟸   ENSRNOT00000082871
RefSeq Acc Id: ENSRNOP00000004295   ⟸   ENSRNOT00000004295
Transcriptome

eQTL   View at Phenogen
WGCNA   View at Phenogen
Tissue/Strain Expression   View at Phenogen


Additional Information

Database Acc Id Source(s)
AGR Gene RGD:620354 AgrOrtholog
BioCyc Gene G2FUF-24657 BioCyc
Ensembl Genes ENSRNOG00000049695 Ensembl, UniProtKB/TrEMBL
  ENSRNOG00000065740 Ensembl, ENTREZGENE, UniProtKB/TrEMBL
Ensembl Transcript ENSRNOT00000004236 ENTREZGENE
  ENSRNOT00000004236.7 UniProtKB/TrEMBL
  ENSRNOT00000082871.2 UniProtKB/TrEMBL
  ENSRNOT00000085582.2 UniProtKB/TrEMBL
  ENSRNOT00000086599.2 UniProtKB/TrEMBL
Gene3D-CATH 1.10.10.820 UniProtKB/TrEMBL
  1.20.5.340 UniProtKB/TrEMBL
  1.20.5.370 UniProtKB/TrEMBL
  1.20.5.4820 UniProtKB/TrEMBL
  1.20.58.530 UniProtKB/TrEMBL
  2.30.30.360 UniProtKB/TrEMBL
  3.40.850.10 UniProtKB/TrEMBL
  6.10.250.2420 UniProtKB/TrEMBL
  Myosin VI head, motor domain, U50 subdomain UniProtKB/TrEMBL
InterPro IQ_motif_EF-hand-BS UniProtKB/TrEMBL
  Kinesin_motor_dom_sf UniProtKB/TrEMBL
  Myosin_head_motor_dom UniProtKB/TrEMBL
  Myosin_N UniProtKB/TrEMBL
  Myosin_S1_N UniProtKB/TrEMBL
  Myosin_tail UniProtKB/TrEMBL
  P-loop_NTPase UniProtKB/TrEMBL
  XRCC4-like_C UniProtKB/TrEMBL
KEGG Report rno:691644 UniProtKB/TrEMBL
NCBI Gene Myh2 ENTREZGENE
PANTHER MYOSIN HEAVY CHAIN, NON-MUSCLE UniProtKB/TrEMBL
  MYOSIN-1 UniProtKB/TrEMBL
  MYOSIN-2 UniProtKB/TrEMBL
  MYOSIN-4 UniProtKB/TrEMBL
Pfam Myosin_head UniProtKB/TrEMBL
  Myosin_N UniProtKB/TrEMBL
  Myosin_tail_1 UniProtKB/TrEMBL
PhenoGen Myh2 PhenoGen
PRINTS MYOSINHEAVY UniProtKB/TrEMBL
PROSITE MYOSIN_MOTOR UniProtKB/TrEMBL
  PS50096 UniProtKB/TrEMBL
  SH3_LIKE UniProtKB/TrEMBL
RatGTEx ENSRNOG00000049695 RatGTEx
  ENSRNOG00000065740 RatGTEx
SMART MYSc UniProtKB/TrEMBL
  SM00015 UniProtKB/TrEMBL
Superfamily-SCOP Myosin rod fragments UniProtKB/TrEMBL
  SSF52540 UniProtKB/TrEMBL
  Tropomyosin UniProtKB/TrEMBL
UniProt A0A0G2K0F5 ENTREZGENE, UniProtKB/TrEMBL
  A0A0G2K1V4_RAT UniProtKB/TrEMBL
  A0A0G2K484_RAT UniProtKB/TrEMBL
  A6HFI0 ENTREZGENE, UniProtKB/TrEMBL
  G3V6E1 ENTREZGENE, UniProtKB/TrEMBL
  Q0GC40_RAT UniProtKB/TrEMBL


Nomenclature History
Date Current Symbol Current Name Previous Symbol Previous Name Description Reference Status
2016-06-29 Myh2  myosin heavy chain 2  Myh2  myosin, heavy chain 2, skeletal muscle, adult  Nomenclature updated to reflect human and mouse nomenclature 1299863 APPROVED
2010-05-05 Myh2  myosin, heavy chain 2, skeletal muscle, adult  Myh2  myosin, heavy polypeptide 2, skeletal muscle, adult  Nomenclature updated to reflect human and mouse nomenclature 1299863 APPROVED
2005-01-20 Myh2  myosin, heavy polypeptide 2, skeletal muscle, adult      Symbol and Name status set to approved 1299863 APPROVED
2002-08-07 Myh2        Symbol and Name status set to provisional 70820 PROVISIONAL