Krt14 (keratin 14) - Rat Genome Database

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Gene: Krt14 (keratin 14) Rattus norvegicus
Analyze
Symbol: Krt14
Name: keratin 14
RGD ID: 1307463
Description: Predicted to enable keratin filament binding activity. Involved in epithelial cell differentiation; response to ionizing radiation; and response to zinc ion. Located in keratin filament. Biomarker of esophagus small cell carcinoma. Human ortholog(s) of this gene implicated in Naegeli-Franceschetti-Jadassohn syndrome; dermatopathia pigmentosa reticularis; and epidermolysis bullosa simplex. Orthologous to human KRT14 (keratin 14); INTERACTS WITH 17alpha-ethynylestradiol; 2,3,7,8-tetrachlorodibenzodioxine; 2-acetamidofluorene.
Type: protein-coding
RefSeq Status: PROVISIONAL
Previously known as: CK-14; cytokeratin-14; K14; Ka14; keratin 14 (epidermolysis bullosa simplex, Dowling-Meara, Koebner); keratin 14, type I; keratin complex 1, acidic, gene 14; keratin, type I cytoskeletal 14; keratin-14; Krt1-14; LOC287701; type I keratin Ka14
RGD Orthologs
Human
Mouse
Bonobo
Dog
Green Monkey
Alliance Genes
More Info more info ...
Latest Assembly: mRatBN7.2 - mRatBN7.2 Assembly
Position:
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
mRatBN7.21085,137,932 - 85,141,990 (-)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl1085,066,802 - 85,171,799 (-)EnsemblmRatBN7.2 Ensembl
Rnor_6.01088,118,029 - 88,122,233 (-)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl1088,055,823 - 88,122,233 (-)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.01087,910,658 - 87,914,716 (-)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.41089,144,357 - 89,148,415 (-)NCBIRGSC3.4RGSC_v3.4rn4RGSC3.4
RGSC_v3.11089,158,726 - 89,162,785 (-)NCBI
Celera1083,857,265 - 83,861,323 (-)NCBICelera
Cytogenetic Map10q31NCBI
JBrowse: View Region in Genome Browser (JBrowse)
Model


Gene-Chemical Interaction Annotations     Click to see Annotation Detail View
1,2-dimethylhydrazine  (ISO)
1-chloro-2,4-dinitrobenzene  (ISO)
17alpha-ethynylestradiol  (EXP,ISO)
17beta-estradiol  (ISO)
2,3,7,8-tetrachlorodibenzodioxine  (EXP,ISO)
2-acetamidofluorene  (EXP)
2-nitroanisole  (EXP)
3,3',4,4',5-pentachlorobiphenyl  (EXP)
4,4'-sulfonyldiphenol  (ISO)
4-Amino-2-nitrophenol  (EXP)
9-cis-retinoic acid  (ISO)
acrylamide  (EXP)
aflatoxin B1  (ISO)
all-trans-4-oxoretinoic acid  (ISO)
all-trans-retinoic acid  (ISO)
alpha-naphthoflavone  (ISO)
ammonium chloride  (EXP)
amphetamine  (EXP)
aristolochic acid  (ISO)
arsenite(3-)  (ISO)
arsenous acid  (ISO)
benzo[a]pyrene  (EXP,ISO)
beta-naphthoflavone  (EXP)
bexarotene  (ISO)
bis(2-chloroethyl) sulfide  (ISO)
bis(2-ethylhexyl) phthalate  (ISO)
bisphenol A  (ISO)
bisphenol F  (ISO)
cadmium atom  (ISO)
cadmium dichloride  (ISO)
cadmium sulfate  (ISO)
calcidiol  (EXP)
chlordecone  (ISO)
chloropicrin  (ISO)
chlorpyrifos  (ISO)
copper atom  (EXP)
copper(0)  (EXP)
dexamethasone  (ISO)
diarsenic trioxide  (ISO)
diazinon  (ISO)
dibutyl phthalate  (ISO)
dimethylarsinic acid  (EXP)
Disperse Blue 1  (EXP)
diuron  (EXP)
endosulfan  (EXP)
enzyme inhibitor  (ISO)
fenamic acid  (EXP)
folic acid  (ISO)
furan  (EXP)
genistein  (ISO)
graphite  (ISO)
indole-3-methanol  (EXP)
isotretinoin  (ISO)
ivermectin  (ISO)
lead nitrate  (ISO)
lead(0)  (ISO)
lead(2+)  (ISO)
melamine  (EXP)
methamphetamine  (ISO)
N,N-bis(2-hydroxypropyl)nitrosamine  (EXP)
N-butyl-N-(4-hydroxybutyl)nitrosamine  (EXP)
N-nitrosodiethylamine  (EXP)
N-nitrosomorpholine  (EXP)
nickel atom  (ISO)
para-Cresidine  (EXP)
paracetamol  (EXP)
pentane-2,3-dione  (ISO)
perfluorododecanoic acid  (EXP)
phenethyl isothiocyanate  (EXP)
phenobarbital  (EXP)
phenyl isocyanate  (ISO)
phenylbutazone  (EXP)
resveratrol  (ISO)
silicon dioxide  (ISO)
sodium arsenite  (EXP,ISO)
sodium fluoride  (ISO)
sulindac sulfide  (ISO)
titanium dioxide  (ISO)
toluene 2,4-diisocyanate  (ISO)
trichloroethene  (EXP)
triclosan  (ISO)
troglitazone  (ISO)
uracil  (EXP)
zinc atom  (EXP,ISO)
zinc(0)  (EXP,ISO)

Gene Ontology Annotations     Click to see Annotation Detail View

Cellular Component

Molecular Function

References

References - curated
# Reference Title Reference Citation
1. Spontaneous metastasis of rat liver epithelial cells transformed with v-raf and v-raf/v-myc: association with different phenotypic properties. Bisgaard HC, etal., Invasion Metastasis. 1997;17(5):240-50.
2. The action of a dietary retinoid on gene expression and cancer induction in electron-irradiated rat skin. Burns FJ, etal., J Radiat Res (Tokyo). 2002 Dec;43 Suppl:S229-32.
3. Point mutations in human keratin 14 genes of epidermolysis bullosa simplex patients: genetic and functional analyses. Coulombe PA, etal., Cell. 1991 Sep 20;66(6):1301-11.
4. Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium. Gaudet P, etal., Brief Bioinform. 2011 Sep;12(5):449-62. doi: 10.1093/bib/bbr042. Epub 2011 Aug 27.
5. Rat ISS GO annotations from GOA human gene data--August 2006 GOA data from the GO Consortium
6. Immunohistochemical expression of keratins 13 and 14 in the lingual epithelium of rats during the morphogenesis of filiform papillae. Iwasaki S, etal., Arch Oral Biol. 2006 May;51(5):416-26. Epub 2005 Nov 4.
7. Transgenic rats overexpressing the human MrgX3 gene show cataracts and an abnormal skin phenotype. Kaisho Y, etal., Biochem Biophys Res Commun. 2005 May 13;330(3):653-7.
8. Modulation of gene expression in precancerous rat esophagus by dietary zinc deficit and replenishment. Liu CG, etal., Cancer Res. 2005 Sep 1;65(17):7790-9.
9. Rat ISS GO annotations from MGI mouse gene data--August 2006 MGD data from the GO Consortium
10. Immunohistochemistry of myoepithelial cells during development of the rat salivary glands. Ogawa Y, etal., Anat Embryol (Berl). 1999 Aug;200(2):215-28.
11. OMIM Disease Annotation Pipeline OMIM Disease Annotation Pipeline
12. GOA pipeline RGD automated data pipeline
13. ClinVar Automated Import and Annotation Pipeline RGD automated import pipeline for ClinVar variants, variant-to-disease annotations and gene-to-disease annotations
14. Data Import for Chemical-Gene Interactions RGD automated import pipeline for gene-chemical interactions
15. Comprehensive gene review and curation RGD comprehensive gene curation
16. Identification of cytokeratin subspecies altered in rat experimental esophageal tumors by subtractive cloning. Wang DY, etal., Cancer Lett 1996 Nov 12;108(1):119-27.
Additional References at PubMed
PMID:7679677   PMID:10852826   PMID:11698679   PMID:11724817   PMID:14673151   PMID:15057822   PMID:15085952   PMID:16489008   PMID:16682203   PMID:17960487   PMID:18262229   PMID:18692037  
PMID:19199708   PMID:19303854   PMID:19487454   PMID:20346438   PMID:21464233   PMID:21630459   PMID:21916889   PMID:23284756   PMID:23599337   PMID:26956522  


Genomics

Comparative Map Data
Krt14
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
mRatBN7.21085,137,932 - 85,141,990 (-)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl1085,066,802 - 85,171,799 (-)EnsemblmRatBN7.2 Ensembl
Rnor_6.01088,118,029 - 88,122,233 (-)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl1088,055,823 - 88,122,233 (-)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.01087,910,658 - 87,914,716 (-)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.41089,144,357 - 89,148,415 (-)NCBIRGSC3.4RGSC_v3.4rn4RGSC3.4
RGSC_v3.11089,158,726 - 89,162,785 (-)NCBI
Celera1083,857,265 - 83,861,323 (-)NCBICelera
Cytogenetic Map10q31NCBI
KRT14
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh381741,582,279 - 41,586,895 (-)NCBIGRCh38GRCh38hg38GRCh38
GRCh38.p13 Ensembl1741,582,279 - 41,586,895 (-)EnsemblGRCh38hg38GRCh38
GRCh371739,738,531 - 39,743,147 (-)NCBIGRCh37GRCh37hg19GRCh37
Build 361736,992,059 - 36,996,673 (-)NCBINCBI36Build 36hg18NCBI36
Build 341736,992,058 - 36,996,673NCBI
Celera1736,391,486 - 36,396,102 (-)NCBICelera
Cytogenetic Map17q21.2NCBI
HuRef1735,501,649 - 35,506,252 (-)NCBIHuRef
CHM1_11739,973,838 - 39,978,454 (-)NCBICHM1_1
T2T-CHM13v2.01742,437,869 - 42,442,485 (-)NCBIT2T-CHM13v2.0
Krt14
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm3911100,093,988 - 100,098,336 (-)NCBIGRCm39GRCm39mm39
GRCm39 Ensembl11100,093,988 - 100,098,374 (-)EnsemblGRCm39 Ensembl
GRCm3811100,203,162 - 100,207,510 (-)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl11100,203,162 - 100,207,548 (-)EnsemblGRCm38mm10GRCm38
MGSCv3711100,064,476 - 100,068,824 (-)NCBIGRCm37MGSCv37mm9NCBIm37
MGSCv3611100,019,252 - 100,023,600 (-)NCBIMGSCv36mm8
Celera11110,819,617 - 110,823,965 (-)NCBICelera
Cytogenetic Map11DNCBI
cM Map1163.43NCBI
LOC100975309
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
PanPan1.11715,948,570 - 15,953,191 (+)NCBIpanpan1.1PanPan1.1panPan2
PanPan1.1 Ensembl1715,948,596 - 15,953,191 (+)Ensemblpanpan1.1panPan2
Mhudiblu_PPA_v01715,730,066 - 15,734,665 (+)NCBIMhudiblu_PPA_v0Mhudiblu_PPA_v0panPan3
KRT14
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.1921,190,672 - 21,195,060 (+)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
CanFam3.1 Ensembl921,156,045 - 21,265,564 (+)EnsemblCanFam3.1canFam3CanFam3.1
Dog10K_Boxer_Tasha920,652,119 - 20,656,507 (+)NCBIDog10K_Boxer_Tasha
ROS_Cfam_1.0921,911,274 - 21,915,662 (+)NCBIROS_Cfam_1.0
UMICH_Zoey_3.1920,697,290 - 20,701,678 (+)NCBIUMICH_Zoey_3.1
UNSW_CanFamBas_1.0920,963,294 - 20,967,682 (+)NCBIUNSW_CanFamBas_1.0
UU_Cfam_GSD_1.0921,067,094 - 21,071,483 (+)NCBIUU_Cfam_GSD_1.0
LOC103243443
(Chlorocebus sabaeus - green monkey)
Green Monkey AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.11664,654,988 - 64,660,327 (+)NCBIChlSab1.1ChlSab1.1chlSab2
ChlSab1.1 Ensembl1664,655,807 - 64,660,319 (+)EnsemblChlSab1.1ChlSab1.1 EnsemblchlSab2
Vero_WHO_p1.0NW_02366607735,500,284 - 35,505,086 (+)NCBIVero_WHO_p1.0Vero_WHO_p1.0

Position Markers
AI626930  
Rat AssemblyChrPosition (strand)SourceJBrowse
mRatBN7.21085,137,852 - 85,137,946 (+)MAPPERmRatBN7.2
Rnor_6.01088,118,096 - 88,118,189NCBIRnor6.0
Rnor_5.01087,910,579 - 87,910,672UniSTSRnor5.0
RGSC_v3.41089,144,278 - 89,144,371UniSTSRGSC3.4
Celera1083,857,186 - 83,857,279UniSTS
Cytogenetic Map10q32.1UniSTS
Krt1-14  
Rat AssemblyChrPosition (strand)SourceJBrowse
mRatBN7.21085,137,787 - 85,138,011 (+)MAPPERmRatBN7.2
Rnor_6.01088,118,031 - 88,118,254NCBIRnor6.0
Rnor_5.01087,910,514 - 87,910,737UniSTSRnor5.0
RGSC_v3.41089,144,213 - 89,144,436UniSTSRGSC3.4
Celera1083,857,121 - 83,857,344UniSTS
Cytogenetic Map10q32.1UniSTS


QTLs in Region (mRatBN7.2)
The following QTLs overlap with this region.    Full Report CSV TAB Printer Gviewer
RGD IDSymbolNameLODP ValueTraitSub TraitChrStartStopSpecies
61427Cia16Collagen induced arthritis QTL 163.2joint integrity trait (VT:0010548)joint inflammation composite score (CMO:0000919)10635789696121100Rat
2303118Mamtr7Mammary tumor resistance QTL 70.003mammary gland integrity trait (VT:0010552)mammary tumor growth rate (CMO:0000344)109658275104670812Rat
2301967Cm73Cardiac mass QTL 734.55heart left ventricle mass (VT:0007031)heart left ventricle weight to body weight ratio (CMO:0000530)101448701189062041Rat
631268Cia21Collagen induced arthritis QTL 213.1joint integrity trait (VT:0010548)joint inflammation composite score (CMO:0000919)1014487011104060283Rat
2316949Gluco60Glucose level QTL 603.7blood glucose amount (VT:0000188)blood glucose level (CMO:0000046)1014487011107057807Rat
1554317Bmd4Bone mineral density QTL 49.40.0001lumbar vertebra mineral mass (VT:0010511)volumetric bone mineral density (CMO:0001553)101981604299406971Rat
724556Pur2Proteinuria QTL 25.5urine protein amount (VT:0005160)urine protein level (CMO:0000591)102242750090627625Rat
61354Pia10Pristane induced arthritis QTL 100.01joint integrity trait (VT:0010548)joint inflammation composite score (CMO:0000919)1023444813104060283Rat
631267Cia20Collagen induced arthritis QTL 203.2joint integrity trait (VT:0010548)joint inflammation composite score (CMO:0000919)1023444813104060283Rat
61325Aia5Adjuvant induced arthritis QTL 50.01joint integrity trait (VT:0010548)joint inflammation composite score (CMO:0000919)1023444813104060283Rat
1298069Bp168Blood pressure QTL 1685.5blood pressure trait (VT:0000183)systolic blood pressure (CMO:0000004)102652195798003205Rat
631542Bp82Blood pressure QTL 826.8arterial blood pressure trait (VT:2000000)systolic blood pressure (CMO:0000004)102652195798952741Rat
1331791Cm31Cardiac mass QTL 313.84606heart mass (VT:0007028)heart wet weight (CMO:0000069)1029299504107211142Rat
1576308Schws1Schwannoma susceptibility QTL 10.0041nervous system integrity trait (VT:0010566)percentage of study population developing trigeminal nerve neurilemmomas during a period of time (CMO:0002017)1040035094102359817Rat
631269Cia22Collagen induced arthritis QTL 228.9joint integrity trait (VT:0010548)joint inflammation composite score (CMO:0000919)1040035094104060283Rat
631270Cia23Collagen induced arthritis QTL 233.9joint integrity trait (VT:0010548)joint inflammation composite score (CMO:0000919)1040035094104060283Rat
631552Vetf2Vascular elastic tissue fragility QTL 24.50.0002aorta elastic tissue integrity trait (VT:0010556)artery internal elastic lamina non-tumorous lesion count (CMO:0001913)104114263386142633Rat
61463Bp12Blood pressure QTL 126.30.0001arterial blood pressure trait (VT:2000000)systolic blood pressure (CMO:0000004)104133325886333258Rat
1298078Stresp5Stress response QTL 52.990.00025blood corticosterone amount (VT:0005345)plasma corticosterone level (CMO:0001173)1042045676104670812Rat
70188BpQTLcluster1Blood pressure QTL cluster 14.864arterial blood pressure trait (VT:2000000)diastolic blood pressure (CMO:0000005)14232313287323132Rat
70188BpQTLcluster1Blood pressure QTL cluster 14.864arterial blood pressure trait (VT:2000000)systolic blood pressure (CMO:0000004)14232313287323132Rat
70188BpQTLcluster1Blood pressure QTL cluster 14.864arterial blood pressure trait (VT:2000000)mean arterial blood pressure (CMO:0000009)14232313287323132Rat
70188BpQTLcluster1Blood pressure QTL cluster 14.864arterial blood pressure trait (VT:2000000)pulse pressure (CMO:0000292)14232313287323132Rat
70198BpQTLcluster9Blood pressure QTL cluster 92.94arterial blood pressure trait (VT:2000000)mean arterial blood pressure (CMO:0000009)104232313287323132Rat
9589030Epfw9Epididymal fat weight QTL 919.240.001epididymal fat pad mass (VT:0010421)epididymal fat pad weight to body weight ratio (CMO:0000658)104444169989441699Rat
7411614Foco18Food consumption QTL 180.001eating behavior trait (VT:0001431)feed conversion ratio (CMO:0001312)104444169989441699Rat
8694173Bw149Body weight QTL 1494.380.001body mass (VT:0001259)body weight gain (CMO:0000420)104444169989441699Rat
2300218Hpcl2Hepatic cholesterol level QTL 2liver cholesterol amount (VT:0010498)liver cholesterol level (CMO:0001597)104502965095600334Rat
631547Bp87Blood pressure QTL 874.5arterial blood pressure trait (VT:2000000)systolic blood pressure (CMO:0000004)104736947092369470Rat
1549846Scl47Serum cholesterol level QTL 473.6blood cholesterol amount (VT:0000180)serum total cholesterol level (CMO:0000363)105057470795574707Rat
70364Bp72Blood pressure QTL 72arterial blood pressure trait (VT:2000000)mean arterial blood pressure (CMO:0000009)105112110096121100Rat
61387Bp1Blood pressure QTL 15.1arterial blood pressure trait (VT:2000000)systolic blood pressure (CMO:0000004)1051770177107211142Rat
61387Bp1Blood pressure QTL 15.1arterial blood pressure trait (VT:2000000)diastolic blood pressure (CMO:0000005)1051770177107211142Rat
1359017Hrtrt21Heart rate QTL 212.4heart pumping trait (VT:2000009)heart rate (CMO:0000002)105177294096772940Rat
631530Tls3T-lymphoma susceptibility QTL 300.0001thymus integrity trait (VT:0010555)percentage of study population developing T-cell lymphomas during a period of time (CMO:0001911)105177461295600334Rat
631535Cm51Cardiac mass QTL 513heart mass (VT:0007028)calculated heart weight (CMO:0000073)105178628291669536Rat
70171Cari1Carrageenan-induced inflammation QTL 14.90.0005hypodermis integrity trait (VT:0010550)inflammatory exudate volume (CMO:0001429)1053797385107211142Rat
70164Bw21Body weight QTL 214.360.00005body mass (VT:0001259)body weight (CMO:0000012)105379749498952626Rat
1354608Cm33Cardiac mass QTL 332.8heart left ventricle mass (VT:0007031)heart left ventricle wet weight (CMO:0000071)105480929299809292Rat
2312662Slep8Serum leptin concentration QTL 80.05blood leptin amount (VT:0005667)serum leptin level (CMO:0000780)1057134272102134272Rat
2312668Scl65Serum cholesterol level QTL 650.001blood cholesterol amount (VT:0000180)serum total cholesterol level (CMO:0000363)1057134272102134272Rat
2312672Insul15Insulin level QTL 150.01blood insulin amount (VT:0001560)serum insulin level (CMO:0000358)1057134272102134272Rat
1549831Bss6Bone structure and strength QTL 64lumbar vertebra strength trait (VT:0010574)vertebra ultimate force (CMO:0001678)1057576521102576521Rat
2293698Bss43Bone structure and strength QTL 435.330.0001lumbar vertebra size trait (VT:0010518)lumbar vertebra cross-sectional area (CMO:0001689)1059209888104209888Rat
2306970Anxrr22Anxiety related response QTL 225.95fear/anxiety-related behavior trait (VT:1000241)number of periods of voluntary immobility (CMO:0001045)106134527698211570Rat
6893336Cm75Cardiac mass QTL 750.10.87heart mass (VT:0007028)heart weight to body weight ratio (CMO:0000074)106134527699703528Rat
1558643Cm44Cardiac mass QTL 444.80.0000368heart mass (VT:0007028)heart wet weight (CMO:0000069)106134527699703528Rat
2313103Bss80Bone structure and strength QTL 8020.0001tibia strength trait (VT:1000284)tibia midshaft endosteal cross-sectional area (CMO:0001716)1062057807107057807Rat
2313105Bss79Bone structure and strength QTL 791.80.0001tibia size trait (VT:0100001)tibia midshaft cross-sectional area (CMO:0001717)1062057807107057807Rat
61449Ciaa2CIA Autoantibody QTL 27.1blood autoantibody amount (VT:0003725)calculated serum anti-type 2 collagen antibody titer (CMO:0001279)1063221094107211142Rat
1357344Bp249Blood pressure QTL 2490.0001arterial blood pressure trait (VT:2000000)systolic blood pressure (CMO:0000004)106674365598003205Rat
2317029Aia19Adjuvant induced arthritis QTL 192.98joint integrity trait (VT:0010548)left rear ankle joint diameter (CMO:0002149)1066978955107211142Rat
2317039Aia6Adjuvant induced arthritis QTL 64.31joint integrity trait (VT:0010548)right rear ankle joint diameter (CMO:0002150)1066978955107211142Rat
10450498Bp384Blood pressure QTL 3840.002arterial blood pressure trait (VT:2000000)mean arterial blood pressure (CMO:0000009)1067750049107211142Rat
1642980Bp300Blood pressure QTL 300arterial blood pressure trait (VT:2000000)systolic blood pressure (CMO:0000004)1068383129107211142Rat
61396Bp9Blood pressure QTL 94.80.0001arterial blood pressure trait (VT:2000000)systolic blood pressure (CMO:0000004)1068420376107211142Rat
2300172Bmd57Bone mineral density QTL 579.80.0001femur mineral mass (VT:0010011)volumetric bone mineral density (CMO:0001553)1069738412107211142Rat
2293646Bss25Bone structure and strength QTL 2510.960.0001femur morphology trait (VT:0000559)femur cross-sectional area (CMO:0001661)1069738412107211142Rat
2293663Bss33Bone structure and strength QTL 339.340.0001femur strength trait (VT:0010010)femur midshaft polar moment of inertia (CMO:0001669)1069738412107211142Rat
6893366Bw106Body weight QTL 1060.30.47body mass (VT:0001259)body weight (CMO:0000012)1070199100107211142Rat
70193Mcs7Mammary carcinoma susceptibility QTL 72.38mammary gland integrity trait (VT:0010552)mammary tumor number (CMO:0000343)1072224939107211142Rat
2298548Neuinf7Neuroinflammation QTL 73.4nervous system integrity trait (VT:0010566)spinal cord RT1-B protein level (CMO:0002132)1072224939107211142Rat
2306793Ean5Experimental allergic neuritis QTL 54.7nervous system integrity trait (VT:0010566)IFNG-secreting splenocyte count (CMO:0002122)107255241693995749Rat
1358188Ept9Estrogen-induced pituitary tumorigenesis QTL 93.9pituitary gland mass (VT:0010496)pituitary gland wet weight (CMO:0000853)107345313696120911Rat
2292617Ept18Estrogen-induced pituitary tumorigenesis QTL 183.9pituitary gland mass (VT:0010496)pituitary gland wet weight (CMO:0000853)107345313696120911Rat
1579919Bp281Blood pressure QTL 2810.01arterial blood pressure trait (VT:2000000)mean arterial blood pressure (CMO:0000009)107437208494965338Rat
631537Oia4Oil induced arthritis QTL 4joint integrity trait (VT:0010548)joint inflammation composite score (CMO:0000919)107563188787055282Rat
10450495Bp383Blood pressure QTL 3830.002arterial blood pressure trait (VT:2000000)mean arterial blood pressure (CMO:0000009)107624608594965338Rat
2292438Bp311Blood pressure QTL 311arterial blood pressure trait (VT:2000000)mean arterial blood pressure (CMO:0000009)1076246085107211142Rat
1302404Cia27Collagen induced arthritis QTL 272.60.0045joint integrity trait (VT:0010548)experimental arthritis severity measurement (CMO:0001459)1076452683107211142Rat
4889492Pancm2Pancreatic morphology QTL 23.2pancreatic beta cell morphology trait (VT:0005217)ratio of insulin-positive cell area to total area of splenic region of pancreas (CMO:0001814)1076748906107211142Rat
724516Uae17Urinary albumin excretion QTL 173.6urine albumin amount (VT:0002871)urine albumin excretion rate (CMO:0000757)107821062285220348Rat
1300107Rf18Renal function QTL 183.41urine output (VT:0003620)timed urine volume (CMO:0000260)107877551698279596Rat
1358915Stresp7Stress response QTL 73.52blood norepinephrine amount (VT:0005663)plasma norepinephrine level (CMO:0001010)107889965587307728Rat
634354Rends3Renal damage susceptibility QTL 30.05kidney blood vessel morphology trait (VT:0000530)organ lesion measurement (CMO:0000677)107981378985160854Rat
631555Bp134Blood pressure QTL 1340.001arterial blood pressure trait (VT:2000000)systolic blood pressure (CMO:0000004)108051528791230079Rat
6893357Bw102Body weight QTL 1020.50.36body mass (VT:0001259)body weight (CMO:0000012)1080515287101325465Rat
2303589Bw87Body weight QTL 872body mass (VT:0001259)body weight (CMO:0000012)1081285008107211142Rat
4889948Bss91Bone structure and strength QTL 914tibia area (VT:1000281)tibia midshaft total cross-sectional area (CMO:0001715)108256485692369470Rat
2317754Glom25Glomerulus QTL 253.5urine protein amount (VT:0005160)urine protein level (CMO:0000591)1082685200107211142Rat
12880055Am11Aortic mass QTL 110.004aorta mass (VT:0002845)aorta weight to aorta length to body weight ratio (CMO:0002722)108400727295933025Rat
2301398Kidm38Kidney mass QTL 380.002kidney mass (VT:0002707)both kidneys wet weight to body weight ratio (CMO:0000340)108400727295933025Rat
2306792Ean4Experimental allergic neuritis QTL 44nervous system integrity trait (VT:0010566)IFNG-secreting splenocyte count (CMO:0002122)108402232193995963Rat

miRNA Target Status

Predicted Target Of
Summary Value
Count of predictions:120
Count of miRNA genes:90
Interacting mature miRNAs:96
Transcripts:ENSRNOT00000005285
Prediction methods:Microtar, Miranda, Rnahybrid, Targetscan
Result types:miRGate_prediction

The detailed report is available here: Full Report CSV TAB Printer

miRNA Target Status data imported from miRGate (http://mirgate.bioinfo.cnio.es/).
For more information about miRGate, see PMID:25858286 or access the full paper here.


Expression


RNA-SEQ Expression
High: > 1000 TPM value   Medium: Between 11 and 1000 TPM
Low: Between 0.5 and 10 TPM   Below Cutoff: < 0.5 TPM

alimentary part of gastrointestinal system circulatory system endocrine system exocrine system hemolymphoid system hepatobiliary system integumental system musculoskeletal system nervous system renal system reproductive system respiratory system appendage
High
Medium 8 8
Low 1 10 2 1 1 4 14 19 10 1
Below cutoff 2 26 31 27 8 27 2 3 4 19 18 1 2

Sequence


Reference Sequences
RefSeq Acc Id: ENSRNOT00000005285   ⟹   ENSRNOP00000005285
RefSeq Status:
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.2 Ensembl1085,137,789 - 85,142,164 (-)Ensembl
Rnor_6.0 Ensembl1088,118,175 - 88,122,233 (-)Ensembl
RefSeq Acc Id: ENSRNOT00000019037   ⟹   ENSRNOP00000019037
RefSeq Status:
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.2 Ensembl1085,066,802 - 85,070,614 (-)Ensembl
RefSeq Acc Id: ENSRNOT00000019133   ⟹   ENSRNOP00000019133
RefSeq Status:
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.2 Ensembl1085,075,835 - 85,080,552 (-)Ensembl
RefSeq Acc Id: ENSRNOT00000019477   ⟹   ENSRNOP00000019477
RefSeq Status:
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.2 Ensembl1085,168,883 - 85,171,799 (-)Ensembl
RefSeq Acc Id: ENSRNOT00000080167   ⟹   ENSRNOP00000069752
RefSeq Status:
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.2 Ensembl1085,137,789 - 85,141,990 (-)Ensembl
RefSeq Acc Id: ENSRNOT00000083895   ⟹   ENSRNOP00000070301
RefSeq Status:
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.2 Ensembl1085,075,835 - 85,142,164 (-)Ensembl
Rnor_6.0 Ensembl1088,055,823 - 88,122,233 (-)Ensembl
RefSeq Acc Id: ENSRNOT00000084619   ⟹   ENSRNOP00000068964
RefSeq Status:
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.2 Ensembl1085,161,424 - 85,164,304 (-)Ensembl
RefSeq Acc Id: ENSRNOT00000086209   ⟹   ENSRNOP00000068575
RefSeq Status:
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.2 Ensembl1085,137,789 - 85,171,799 (-)Ensembl
RefSeq Acc Id: ENSRNOT00000100338   ⟹   ENSRNOP00000089695
RefSeq Status:
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.2 Ensembl1085,066,802 - 85,080,649 (-)Ensembl
RefSeq Acc Id: ENSRNOT00000102784   ⟹   ENSRNOP00000087249
RefSeq Status:
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.2 Ensembl1085,075,835 - 85,142,164 (-)Ensembl
RefSeq Acc Id: NM_001008751   ⟹   NP_001008751
RefSeq Status: PROVISIONAL
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.21085,137,932 - 85,141,990 (-)NCBI
Rnor_6.01088,118,175 - 88,122,233 (-)NCBI
Rnor_5.01087,910,658 - 87,914,716 (-)NCBI
RGSC_v3.41089,144,357 - 89,148,415 (-)RGD
Celera1083,857,265 - 83,861,323 (-)RGD
Sequence:
Protein Sequences
Protein RefSeqs NP_001008751 (Get FASTA)   NCBI Sequence Viewer  
GenBank Protein DAA04481 (Get FASTA)   NCBI Sequence Viewer  
  EDM06022 (Get FASTA)   NCBI Sequence Viewer  
  Q6IFV1 (Get FASTA)   NCBI Sequence Viewer  
Reference Sequences
RefSeq Acc Id: NP_001008751   ⟸   NM_001008751
- UniProtKB: O35813 (UniProtKB/Swiss-Prot),   Q6IFV1 (UniProtKB/Swiss-Prot)
- Sequence:
RefSeq Acc Id: ENSRNOP00000005285   ⟸   ENSRNOT00000005285
RefSeq Acc Id: ENSRNOP00000070301   ⟸   ENSRNOT00000083895
RefSeq Acc Id: ENSRNOP00000019037   ⟸   ENSRNOT00000019037
RefSeq Acc Id: ENSRNOP00000068575   ⟸   ENSRNOT00000086209
RefSeq Acc Id: ENSRNOP00000019477   ⟸   ENSRNOT00000019477
RefSeq Acc Id: ENSRNOP00000068964   ⟸   ENSRNOT00000084619
RefSeq Acc Id: ENSRNOP00000087249   ⟸   ENSRNOT00000102784
RefSeq Acc Id: ENSRNOP00000069752   ⟸   ENSRNOT00000080167
RefSeq Acc Id: ENSRNOP00000089695   ⟸   ENSRNOT00000100338
RefSeq Acc Id: ENSRNOP00000019133   ⟸   ENSRNOT00000019133
Protein Domains
IF rod

Protein Structures
Name Modeler Protein Id AA Range Protein Structure
AF-Q6IFV1-F1-model_v2 AlphaFold Q6IFV1 1-485 view protein structure

Transcriptome

eQTL   View at Phenogen
WGCNA   View at Phenogen
Tissue/Strain Expression   View at Phenogen

Promoters
RGD ID:13697710
Promoter ID:EPDNEW_R8235
Type:single initiation site
Name:Krt14_1
Description:keratin 14
SO ACC ID:SO:0000170
Source:EPDNEW (Eukaryotic Promoter Database, http://epd.vital-it.ch/)
Experiment Methods:Single-end sequencing.
Position:
Rat AssemblyChrPosition (strand)Source
Rnor_6.01088,122,297 - 88,122,357EPDNEW

Strain Variation

Strain Sequence Variants (mRatBN7.2)
ACI/EurMcwi (2019)
Visual CSV TAB Printer
Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: MCW
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
ACI/N (2020)
Visual CSV TAB Printer
Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: NIH
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
BN-Lx/CubMcwi (2019)
Visual CSV TAB Printer
Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: MCW
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
BN/NHsdMcwi (2019)
Visual CSV TAB Printer
Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: MCW
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
BN/NHsdMcwi (2020)
Visual CSV TAB Printer
Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: MCW
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
BN/SsN (2020)
Visual CSV TAB Printer
Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: NIH
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
BUF/N (2020)
Visual CSV TAB Printer
Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: NIH
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
BXH2/CubMcwi (2020)
Visual CSV TAB Printer
Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: MCW
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
BXH3/CubMcwi (2020)
Visual CSV TAB Printer
Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: MCW
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
DA/OlaHsd (2019)
Visual CSV TAB Printer
Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: Envigo
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
F344/DuCrl (2019)
Visual CSV TAB Printer
Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: Charles River
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
F344/N (2020)
Visual CSV TAB Printer
Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: NIH
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
F344/NCrl (2019)
Visual CSV TAB Printer
Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: Charles River
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
F344/Stm (2019)
Visual CSV TAB Printer
Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: Japan
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
FHH/EurMcwi (2019)
Visual CSV TAB Printer
Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: MCW
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
FXLE16/Stm (2020)
Visual CSV TAB Printer
Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: Japan
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
FXLE18/Stm (2020)
Visual CSV TAB Printer
Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: Japan
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
GK/FarMcwi (2019)
Visual CSV TAB Printer
Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: MCW
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
HXB10/IpcvMcwi (2019)
Visual CSV TAB Printer
Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: MCW
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
HXB2/IpcvMcwi (2019)
Visual CSV TAB Printer
Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: MCW
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
HXB20/IpcvMcwi (2020)
Visual CSV TAB Printer
Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: MCW
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
HXB31/IpcvMcwi (2019)
Visual CSV TAB Printer
Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: MCW
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
HXB4/IpcvMcwi (2020)
Visual CSV TAB Printer
Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: MCW
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
LE/Stm (2019)
Visual CSV TAB Printer
Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: MCW
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
LEW/Crl (2019)
Visual CSV TAB Printer
Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: Charles River
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
LEXF10A/StmMcwi (2020)
Visual CSV TAB Printer
Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: MCW
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
LEXF11/Stm (2020)
Visual CSV TAB Printer
Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: Japan
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
LEXF1A/Stm (2019)
Visual CSV TAB Printer
Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: Japan
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
LEXF1C/Stm (2019)
Visual CSV TAB Printer
Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: Japan
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
LEXF2B/Stm (2019)
Visual CSV TAB Printer
Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: Japan
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
LEXF3/Stm (2020)
Visual CSV TAB Printer
Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: Japan
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
LEXF4/Stm (2020)
Visual CSV TAB Printer
Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: Japan
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
LH/MavRrrcAek (2020)
Visual CSV TAB Printer
Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: Kwitek
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
LL/MavRrrcAek (2020)
Visual CSV TAB Printer
Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: Kwitek
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
LN/MavRrrcAek (2020)
Visual CSV TAB Printer
Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: Kwitek
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
M520/N (2020)
Visual CSV TAB Printer
Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: NIH
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
M520/NRrrcMcwi (2019)
Visual CSV TAB Printer
Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: MCW
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
MR/N (2020)
Visual CSV TAB Printer
Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: NIH
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
MWF/Hsd (2019)
Visual CSV TAB Printer
Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: MCW
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
PVG/Seac (2019)
Visual CSV TAB Printer
Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: Japan
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
SHR/OlalpcvMcwi (2019)
Visual CSV TAB Printer
Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: MCW
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
SHRSP/A3NCrl (2019)
Visual CSV TAB Printer
Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: Charles River
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
SR/JrHsd (2020)
Visual CSV TAB Printer
Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: Envigo
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
SS/JrHsdMcwi (2019)
Visual CSV TAB Printer
Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: MCW
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
WAG/RijCrl (2020)
Visual CSV TAB Printer
Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: Charles River
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
WKY/N (2020)
Visual CSV TAB Printer
Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: NIH
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
WKY/NCrl (2019)
Visual CSV TAB Printer
Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: Charles River
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
WN/N (2020)
Visual CSV TAB Printer
Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: NIH
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
Damaging Variants


Assembly: Rnor_6.0

Chromosome Start Pos End Pos Reference Nucleotide Variant Nucleotide Variant Type Strain
10 88121690 88121691 T G snv LN/MavRrrcAek (2020), F344/N (2020)
10 88121726 88121727 T G snv ACI/EurMcwi (2019), M520/NRrrcMcwi (2019), BN/NHsdMcwi (2019), BN/SsN (2020), F344/DuCrl (2019), F344/NCrl (2019), F344/N (2020), F344/Stm (2019), FHH/EurMcwi (2019), LEXF1A/Stm (2019), LEXF1C/Stm (2019), LE/Stm (2019), LH/MavRrrcAek (2020), MR/N (2020), SHR/OlalpcvMcwi (2019), WAG/RijCrl (2020), M520/N (2020), CDR, CDS, BXH2/CubMcwi (2020), BXH3/CubMcwi (2020), FXLE16/Stm (2020), FXLE18/Stm (2020), HXB4/IpcvMcwi (2020), LEXF11/Stm (2020), LEXF2B/Stm (2019), LEXF4/Stm (2020), LN/MavRrrcAek (2020), LEXF10A/StmMcwi (2020), ACI/N (2020)
10 88121801 88121802 C T snv SS/JrHsdMcwi (MCW)
10 88121813 88121814 G A snv SR/JrHsd (MCW), COP/CrCrl (MCW & UW), FHL/EurMcwi (MCW), SBN/Ygl (MCW)
10 88121819 88121820 T G snv SBN/Ygl (MCW), SR/JrHsd (MCW), SS/JrHsdMcwi (MCW), ACI/EurMcwi (2019), BUF/N (2020), LEXF1A/Stm (2019), LEXF1C/Stm (2019), LE/Stm (2019), SHR/OlalpcvMcwi (2019), GH/OmrMcwi (MCW), FHL/EurMcwi (MCW), FHH/EurMcwi (MCW), COP/CrCrl (MCW & UW), ACI/EurMcwi (MCW), SBH/Ygl (MCW)
10 88121825 88121826 G T snv FHL/EurMcwi (MCW), FHH/EurMcwi (MCW), COP/CrCrl (MCW & UW), ACI/EurMcwi (MCW), GH/OmrMcwi (MCW), SHR/OlalpcvMcwi (2019), LE/Stm (2019), LEXF1C/Stm (2019), LEXF1A/Stm (2019), BUF/N (2020), ACI/EurMcwi (2019), SS/JrHsdMcwi (MCW), SR/JrHsd (MCW), SBN/Ygl (MCW), SBH/Ygl (MCW)
10 88121830 88121831 G T snv ACI/EurMcwi (MCW), SHR/OlalpcvMcwi (2019), FHH/EurMcwi (MCW), FHL/EurMcwi (MCW), LE/Stm (2019), LEXF1C/Stm (2019), LEXF1A/Stm (2019), BUF/N (2020), ACI/EurMcwi (2019), SS/JrHsdMcwi (MCW), SR/JrHsd (MCW), SBN/Ygl (MCW), SBH/Ygl (MCW), GH/OmrMcwi (MCW), COP/CrCrl (MCW & UW)
10 88121834 88121835 C A snv ACI/EurMcwi (MCW), COP/CrCrl (MCW & UW), FHH/EurMcwi (MCW), FHL/EurMcwi (MCW), SBN/Ygl (MCW), SR/JrHsd (MCW), SS/JrHsdMcwi (MCW), ACI/EurMcwi (2019), BUF/N (2020), LEXF1C/Stm (2019), LE/Stm (2019), SHR/OlalpcvMcwi (2019), GH/OmrMcwi (MCW), SBH/Ygl (MCW), LEXF1A/Stm (2019)
10 88121887 88121888 C T snv Buf/N (MCW), SBH/Ygl (MCW), GH/OmrMcwi (MCW), ACI/EurMcwi (MCW), CDR
10 88121891 88121892 C T snv SS/JrHsdMcwi (MCW), SBN/Ygl (MCW), FHL/EurMcwi (MCW), FHH/EurMcwi (MCW), ACI/EurMcwi (MCW), COP/CrCrl (MCW & UW)
10 88122169 88122170 C A snv ACI/EurMcwi (MCW), COP/CrCrl (MCW & UW), ACI/N (MCW), Buf/N (MCW), F344/NRrrc (MCW), MR/N (MCW), M520/N (MCW)
10 88122219 88122220 G T snv CDR


Assembly: Rnor_5.0

Chromosome Start Pos End Pos Reference Nucleotide Variant Nucleotide Variant Type Strain
10 87914193 87914194 G A snv F344/Jcl (KyushuU), ZF (KyushuU)
10 87914207 87914208 G T snv F344/DuCrlCrlj (KyushuU), F344/Jcl (KyushuU)
10 87914370 87914371 C T snv GH/OmrMcwi (MCW), DOB/Oda (KyushuU), BDIX/NemOda (KyushuU), F344/Jcl (KyushuU), IS-Tlk/Kyo (KyushuU), HTX/Kyo (KyushuU), LE/Stm (KyushuU), NIG-III/Hok (KyushuU), BDIX.Cg-Tal/NemOda (KyushuU), COP/CrCrl (MCW & UW), SBH/Ygl (MCW)
10 87914652 87914653 C A snv COP/CrCrl (MCW & UW), ACI/EurMcwi (MCW), BDIX.Cg-Tal/NemOda (KyushuU), SBN/Ygl (MCW), SBH/Ygl (MCW), GH/OmrMcwi (MCW), FHL/EurMcwi (MCW), FHH/EurMcwi (MCW)


Assembly: RGSC_v3.4

Chromosome Start Pos End Pos Reference Nucleotide Variant Nucleotide Variant Type Strain
10 89148069 89148070 C T snv BUF/N (KNAW), GH/OmrMcwi (MCW)
10 89148351 89148352 C A snv FHL/EurMcwi (MCW), SR/JrHsd (MCW), ACI/N (KNAW), BUF/N (KNAW), LE/Stm (KNAW), M520/N (KNAW), MR/N (KNAW), COP/CrCrl (MCW & UW), GH/OmrMcwi (MCW), FHH/EurMcwi (MCW), ACI/EurMcwi (MCW), F344/NRrrc (KNAW)


Additional Information

Database Acc Id Source(s)
AGR Gene RGD:1307463 AgrOrtholog
BioCyc Gene G2FUF-23248 BioCyc
Ensembl Genes ENSRNOG00000003899 Ensembl, ENTREZGENE, UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
Ensembl Protein ENSRNOP00000005285 ENTREZGENE, UniProtKB/Swiss-Prot
  ENSRNOP00000019037.6 UniProtKB/TrEMBL
  ENSRNOP00000068575.2 UniProtKB/TrEMBL
  ENSRNOP00000069752.2 UniProtKB/TrEMBL
  ENSRNOP00000070301.2 UniProtKB/TrEMBL
  ENSRNOP00000087249.1 UniProtKB/TrEMBL
  ENSRNOP00000089695.1 UniProtKB/TrEMBL
Ensembl Transcript ENSRNOT00000005285 ENTREZGENE, UniProtKB/Swiss-Prot
  ENSRNOT00000019037.7 UniProtKB/TrEMBL
  ENSRNOT00000080167.2 UniProtKB/TrEMBL
  ENSRNOT00000083895.2 UniProtKB/TrEMBL
  ENSRNOT00000086209.2 UniProtKB/TrEMBL
  ENSRNOT00000100338.1 UniProtKB/TrEMBL
  ENSRNOT00000102784.1 UniProtKB/TrEMBL
InterPro IF_conserved UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  IF_rod_dom UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  Keratin_I UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
KEGG Report rno:287701 UniProtKB/Swiss-Prot
NCBI Gene 287701 ENTREZGENE
PANTHER PTHR23239 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
Pfam Filament UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
PhenoGen Krt14 PhenoGen
PRINTS TYPE1KERATIN UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
PROSITE IF_ROD_1 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  IF_ROD_2 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
SMART Filament UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
UniProt A0A0G2JT54_RAT UniProtKB/TrEMBL
  A0A0G2JW58_RAT UniProtKB/TrEMBL
  A0A0G2JXJ9_RAT UniProtKB/TrEMBL
  A0A8I6A5I5_RAT UniProtKB/TrEMBL
  A0A8I6GIB2_RAT UniProtKB/TrEMBL
  A0A8L2Q9T0_RAT UniProtKB/TrEMBL
  K1C14_RAT UniProtKB/Swiss-Prot
  O35813 ENTREZGENE
  Q6IFV1 ENTREZGENE
UniProt Secondary O35813 UniProtKB/Swiss-Prot


Nomenclature History
Date Current Symbol Current Name Previous Symbol Previous Name Description Reference Status
2016-03-15 Krt14  keratin 14  Krt14  keratin 14, type I  Nomenclature updated to reflect human and mouse nomenclature 1299863 APPROVED
2015-01-28 Krt14  keratin 14, type I  Krt14  keratin 14  Nomenclature updated to reflect human and mouse nomenclature 1299863 APPROVED
2008-11-11 Krt14  keratin 14  Krt14  keratin 14 (epidermolysis bullosa simplex, Dowling-Meara, Koebner)  Nomenclature updated to reflect human and mouse nomenclature 1299863 APPROVED
2008-09-09 Krt14  keratin 14 (epidermolysis bullosa simplex, Dowling-Meara, Koebner)  Krt14  keratin 14  Nomenclature updated to reflect human and mouse nomenclature 1299863 APPROVED
2008-03-04 Krt14  keratin 14  Krt1-14  keratin complex 1, acidic, gene 14  Nomenclature updated to reflect human and mouse nomenclature 1299863 APPROVED
2005-12-06 Krt1-14  keratin complex 1, acidic, gene 14  Krt1-14_predicted  keratin complex 1, acidic, gene 14 (predicted)  Symbol and Name updated 1559027 APPROVED
2005-01-12 Krt1-14_predicted  keratin complex 1, acidic, gene 14 (predicted)      Symbol and Name status set to approved 70820 APPROVED