Gene: Chrne (cholinergic receptor nicotinic epsilon subunit) Rattus norvegicus
Symbol: Chrne
Name: cholinergic receptor nicotinic epsilon subunit
Description: ENCODES a protein that exhibits acetylcholine-gated cation-selective channel activity; INVOLVED IN cation transport; skeletal muscle contraction; regulation of membrane potential (ortholog); PARTICIPATES IN acetylcholine signaling pathway via nicotinic acetylcholine receptor; ASSOCIATED WITH congenital myasthenic syndrome 1B (ortholog); congenital myasthenic syndrome 4B (ortholog); congenital myasthenic syndrome, fast-channel (ortholog); FOUND IN acetylcholine-gated channel complex; postsynaptic membrane (ortholog); INTERACTS WITH 6-propyl-2-thiouracil; acetylcholine; acrylamide
Type: protein-coding
Also known as: acetylcholine receptor epsilon; acetylcholine receptor subunit epsilon; cholinergic receptor, nicotinic epsilon; cholinergic receptor, nicotinic, epsilon; cholinergic receptor, nicotinic, epsilon (muscle); cholinergic receptor, nicotinic, epsilon polypeptide; epsilon-subunit; gene for acetylcholine receptor epsilon subunit; nAChR
Homo sapiens (human) : CHRNE (cholinergic receptor nicotinic epsilon subunit)  HGNC  Alliance
Mus musculus (house mouse) : Chrne (cholinergic receptor, nicotinic, epsilon polypeptide)  MGI  Alliance
Chinchilla lanigera (long-tailed chinchilla) : Chrne (cholinergic receptor nicotinic epsilon subunit)
Pan paniscus (bonobo/pygmy chimpanzee) : CHRNE (cholinergic receptor nicotinic epsilon subunit)
Canis lupus familiaris (dog) : CHRNE (cholinergic receptor nicotinic epsilon subunit)
Ictidomys tridecemlineatus (thirteen-lined ground squirrel) : Chrne (cholinergic receptor nicotinic epsilon subunit)
more info ...
Latest Assembly: Rnor_6.0 - RGSC Genome Assembly v6.0
Rat AssemblyChrPosition (strand)SourceGenome Browsers
Rnor_6.01057,238,960 - 57,246,750 (-)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_5.01056,984,503 - 56,992,199 (-)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.41057,497,192 - 57,501,511 (-)NCBIRGSC3.4rn4RGSC3.4
RGSC_v3.11057,510,815 - 57,515,134 (-)NCBI
Celera1054,476,876 - 54,481,195 (-)NCBICelera
Cytogenetic Map10q24NCBI
JBrowse: View Region in Genome Browser (JBrowse)

Disease Annotations
Gene-Chemical Interaction Annotations
Gene Ontology Annotations
Molecular Pathway Annotations
References - curated
References - uncurated
RGD Disease Portals


Comparative Map Data
QTLs in Region (Rnor_6.0)
miRNA Target Status


Nucleotide Sequences
Protein Sequences

Strain Variation

Strain Sequence Variants

Additional Information

External Database Links
Nomenclature History
RGD Curation Notes
More on Chrne
Alliance Gene
Ensembl Gene
JBrowse: rn5 rn6
NCBI Genome Data Viewer

RGD Object Information
RGD ID: 2353
Created: 2000-05-25
Species: Rattus norvegicus
Last Modified: 2018-03-20
Status: ACTIVE