Bw96 QTL Report (Rattus norvegicus) - Rat Genome Database

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QTL: Bw96 (Body weight QTL 96) Rattus norvegicus

Symbol: Bw96
Name: Body weight QTL 96
RGD ID: 2313055
Previously known as: Pqctf9
Trait: body mass   (VT:0001259)    
Measurement Type: body weight   (CMO:0000012)    
LOD Score: 3.6
P Value: 1.0E-4
Variance: Not Available
Position
Rat AssemblyChrPosition (strand)SourceJBrowse
GRCr81020,110,614 - 65,110,614RGD_MAPPER_PIPELINE
mRatBN7.21019,606,483 - 64,606,483RGD_MAPPER_PIPELINEmRatBN7.2
Rnor_6.01019,958,696 - 21,524,070RGD_MAPPER_PIPELINERnor6.0
Rnor_5.01019,835,926 - 21,392,459RGDRnor5.0
RGSC_v3.41020,018,844 - 21,607,865RGDRGSC3.4
Cross Type: intercross
Strains Crossed: GK/KyoSwe F344/DuCrlSwe 
JBrowse: View Region in Genome Browser (JBrowse)
Model




  
Object Symbol
Species
Term
Qualifier
Evidence
With
Reference
Notes
Source
Original Reference(s)
Bw96Ratosteoporosis  IAGP 2312767 RGD 

Object Symbol
Species
Term
Qualifier
Evidence
With
Reference
Notes
Source
Original Reference(s)
Bw96Ratincreased bone mineral density  IDA 2312767as compared to malesRGD 

Clinical Measurement
Object Symbol
Species
Term
Qualifier
Evidence
With
Reference
Notes
Source
Original Reference(s)
Bw96Ratbody weight  IDA 2312767 RGD 

Experimental Condition
Object Symbol
Species
Term
Qualifier
Evidence
With
Reference
Notes
Source
Original Reference(s)
Bw96Ratcontrolled bile acid content diet  IDA 23127670.5%RGD 
Bw96Ratcontrolled cholesterol content diet  IDA 23127672%RGD 
Bw96Ratcontrolled olive oil content diet  IDA 231276720%RGD 

Measurement Method
Object Symbol
Species
Term
Qualifier
Evidence
With
Reference
Notes
Source
Original Reference(s)
Bw96Ratbody weighing method  IDA 2312767 RGD 

Rat Strain
Object Symbol
Species
Term
Qualifier
Evidence
With
Reference
Notes
Source
Original Reference(s)
Bw96RatF344/DuCrlSwe  IEA 2312767 RGD 
Bw96RatGK/KyoSwe  IEA 2312767 RGD 

Vertebrate Trait
Object Symbol
Species
Term
Qualifier
Evidence
With
Reference
Notes
Source
Original Reference(s)
Bw96Ratbody mass  IDA 2312767 RGD 


#
Reference Title
Reference Citation
1. Genetic regulation of bone traits is influenced by sex and reciprocal cross in F(2) progeny from GK and F344 rats. Lagerholm S, etal., J Bone Miner Res. 2009 Jun;24(6):1066-74.

Related QTL Description Reference
Bmd80 maps to same region RGD:2312767



1 to 20 of 1059 rows
The following Genes overlap with this region.    Full Report CSV TAB Printer Analysis Tools
RGD ID
Symbol
Name
Chr
Start
Stop
Species
69311Slit3slit guidance ligand 3101957179820156634Rat
41338383LOC120095445small nucleolar RNA SNORA17101966091719661046Rat
2325546Mir218-2microRNA 218-2102006845120068560Rat
41265420LOC120095247uncharacterized LOC120095247102013874520156177Rat
1310531Pank3pantothenate kinase 3102022912920252955Rat
2325579Mir103a1microRNA 103a-1102024441220244497Rat
1562841Fbll1fibrillarin-like 1102025865620260299Rat
1309215Rars1arginyl-tRNA synthetase 1102027074420295192Rat
1308329Wwc1WW and C2 domain containing 1102030073520454393Rat
727907Tenm2teneurin transmembrane protein 2102048066221706415Rat
11466937LOC108352202uncharacterized LOC108352202102062503820628112Rat
41165016LOC120095252uncharacterized LOC120095252102063926520642557Rat
11424155LOC108352204uncharacterized LOC108352204102073121220732795Rat
41270792LOC120095249uncharacterized LOC120095249102122099721294620Rat
41296108LOC120095253uncharacterized LOC120095253102125963321273194Rat
41246647LOC120095250uncharacterized LOC120095250102149522821532145Rat
41261886LOC120095384small nucleolar RNA SNORA72102186971021869841Rat
11469336LOC108352072uncharacterized LOC108352072102194260222287277Rat
1588527Thrap3-ps2thyroid hormone receptor associated protein 3, pseudogene 2102269983922705360Rat
1559806Hmgb1-ps15high-mobility group box 1, pseudogene 15102307433023074956Rat

1 to 20 of 1059 rows
1 to 20 of 1127 rows
The following Markers overlap with this region.    Full Report CSV TAB Printer Gviewer
RGD ID
Symbol
Expected Size
Chr
Start
Stop
Species
Match
10141D10Wox15254106322103763221291Ratregion
10142D10Arb9129106322109463221223Ratregion
10195D10Wox14158105477580754775965Ratregion
10196D10Mgh22270105477574554776015Ratregion
10664D10Uwm1158105467188954672047Ratregion
10792D10Wox10850103840624038407090Ratregion
10794D10Mgh9130103777589037776020Ratregion
10795D10Wox9188103777583737776025Ratregion
10874D10Rat83173104539382945394002Ratregion
10949D10Wox11150105178628251786432Ratregion
10995D10Wox24138106381361463813752Ratregion
33846D10Mit2188106364253963642727Ratregion
33909D10Mit4188103539226735392457Ratregion
34053D10Mit3148104003509440035242Ratregion
34176D10Mgh24122105259574452595866Ratregion
34320D10Mgh7215105409867454098889Ratregion
34359D10Mgh11134102929950429299638Ratregion
34445D10Mgh6137106134527661345413Ratregion
34648D10Mgh14115106415546964155584Ratregion
34669D10Mgh20172105177444051774612Ratregion
1 to 20 of 1127 rows

Flank 1: (D10Mit16)
Rat AssemblyChrPosition (strand)Source
GRCr81020,110,614 - 20,110,705 (+)Marker Load Pipeline
mRatBN7.21019,606,483 - 19,606,574 (+)MAPPER
Rnor_6.01019,958,696 - 19,958,786NCBI
Rnor_5.01019,835,926 - 19,836,016UniSTS
RGSC_v3.41020,018,844 - 20,018,935RGD
RGSC_v3.41020,018,845 - 20,018,935UniSTS
RGSC_v3.11020,019,893 - 20,019,984RGD
Celera1019,236,271 - 19,236,361UniSTS
SHRSP x BN Map1020.45UniSTS
SHRSP x BN Map1020.45RGD
FHH x ACI Map1014.0RGD
Cytogenetic Map10q12UniSTS
Flank 2: (D10Mit5)
Rat AssemblyChrPosition (strand)Source
Rnor_6.01021,523,906 - 21,524,070NCBI
Rnor_5.01021,392,295 - 21,392,459UniSTS
RGSC_v3.41021,607,719 - 21,607,865RGD
RGSC_v3.41021,607,720 - 21,607,865UniSTS
RGSC_v3.11021,608,769 - 21,608,914RGD
RH 3.4 Map10240.41UniSTS
RH 3.4 Map10240.41RGD
RH 2.0 Map10246.1RGD
Cytogenetic Map10q12UniSTS


1 to 10 of 115 rows
The following QTLs overlap with this region.    Full Report CSV TAB Printer Gviewer
RGD ID
Symbol
Name
LOD
P Value
Trait
Sub Trait
Chr
Start
Stop
Species
61441Btemp1Thermal response to stress QTL 14body temperature trait (VT:0005535)core body temperature (CMO:0001036)103539245763642539Rat
1549846Scl47Serum cholesterol level QTL 473.6blood cholesterol amount (VT:0000180)serum total cholesterol level (CMO:0000363)105057470795574707Rat
9589136Insul27Insulin level QTL 2710.460.001blood insulin amount (VT:0001560)plasma insulin level (CMO:0000342)101147401056474010Rat
1578779Tcas10Tongue tumor susceptibility QTL 103.12tongue integrity trait (VT:0010553)number of squamous cell tumors of the tongue with diameter greater than 3 mm (CMO:0001950)103129743976297439Rat
631564Apr3Acute phase response QTL 33.9blood interleukin-6 amount (VT:0008595)plasma interleukin-6 level (CMO:0001927)101527595560275955Rat
631552Vetf2Vascular elastic tissue fragility QTL 24.50.0002aorta elastic tissue integrity trait (VT:0010556)artery internal elastic lamina non-tumorous lesion count (CMO:0001913)104114263386142633Rat
61449Ciaa2CIA Autoantibody QTL 27.1blood autoantibody amount (VT:0003725)calculated serum anti-type 2 collagen antibody titer (CMO:0001279)1063221094107211142Rat
631554Bp133Blood pressure QTL 1330.005arterial blood pressure trait (VT:2000000)systolic blood pressure (CMO:0000004)1074336463851208Rat
631557Bp136Blood pressure QTL 1360.003arterial blood pressure trait (VT:2000000)systolic blood pressure (CMO:0000004)103063205375632053Rat
1549831Bss6Bone structure and strength QTL 64lumbar vertebra strength trait (VT:0010574)vertebra ultimate force (CMO:0001678)1057576521102576521Rat

1 to 10 of 115 rows


Note Type Note Reference
qtl_cross_type intercross  
qtl_general number of animals used: 98 females 2312767
qtl_general lineage: 2 seperate F2 intercrosses were generated one from grandmaternal GK and grandpaternal F344 other from grandmaternal F344 and grandpaternal GK 2312767
qtl_general measurement method: in the last 3 months modified fat-enriched chow was given; animals were killed at 215 days of age body length and weight recorded; left tibia cleaned at stored in 70% alcohol for pQCT (peripheral quantitative computed tomography) 2312767
qtl_general software used:one-way ANOVA and MAP MANAGER/QTX 2312767