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Gene: Hint1 (histidine triad nucleotide binding protein 1) Rattus norvegicus
Symbol: Hint1
Name: histidine triad nucleotide binding protein 1
Description: Predicted to have hydrolase activity. Predicted to be involved in several processes, including intrinsic apoptotic signaling pathway by p53 class mediator; positive regulation of calcium-mediated signaling; and purine ribonucleotide catabolic process. Predicted to localize to cytosol; histone deacetylase complex; and plasma membrane. Human ortholog(s) of this gene implicated in Gamstorp-Wohlfart syndrome. Orthologous to human HINT1 (histidine triad nucleotide binding protein 1); INTERACTS WITH 2,3,7,8-tetrachlorodibenzodioxine; benzo[a]pyrene; bisphenol A.
Type: protein-coding
Also known as: 17 kDa inhibitor of protein kinase C; adenosine 5'-monophosphoramidase; histidine triad nucleotide-binding protein 1; LOC690660; Pkci; PKCI-1; Prkci; protein kinase C inhibitor 1; protein kinase C, iota; protein kinase C-interacting protein 1; similar to Histidine triad nucleotide-binding protein 1 (Adenosine 5-monophosphoramidase) (Protein kinase C inhibitor 1) (Protein kinase C-interacting protein 1) (PKCI-1)
Homo sapiens (human) : HINT1 (histidine triad nucleotide binding protein 1)  HGNC  Alliance
Mus musculus (house mouse) : Hint1 (histidine triad nucleotide binding protein 1)  MGI  Alliance
Chinchilla lanigera (long-tailed chinchilla) : Hint1 (histidine triad nucleotide binding protein 1)
Pan paniscus (bonobo/pygmy chimpanzee) : HINT1 (histidine triad nucleotide binding protein 1)
Canis lupus familiaris (dog) : HINT1 (histidine triad nucleotide binding protein 1)
Ictidomys tridecemlineatus (thirteen-lined ground squirrel) : Hint1 (histidine triad nucleotide binding protein 1)
Sus scrofa (pig) : HINT1 (histidine triad nucleotide binding protein 1)
Chlorocebus sabaeus (African green monkey) : HINT1 (histidine triad nucleotide binding protein 1)
Heterocephalus glaber (naked mole-rat) : Hint1 (histidine triad nucleotide binding protein 1)
more info ...
Related Pseudogenes: Hint1-ps1  
Latest Assembly: Rnor_6.0 - RGSC Genome Assembly v6.0
Rat AssemblyChrPosition (strand)SourceGenome Browsers
Rnor_6.01040,208,236 - 40,211,981 (+)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl1040,208,223 - 40,211,975 (+)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.01039,980,504 - 39,984,249 (+)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.41040,271,895 - 40,275,640 (+)NCBIRGSC3.4rn4RGSC3.4
Celera1038,327,662 - 38,331,407 (+)NCBICelera
Cytogenetic Map10q22NCBI
JBrowse: View Region in Genome Browser (JBrowse)

Disease Annotations
Gene-Chemical Interaction Annotations
Gene Ontology Annotations
References - curated
References - uncurated


Comparative Map Data
Position Markers
QTLs in Region (Rnor_6.0)
miRNA Target Status


RNA-SEQ Expression


Nucleotide Sequences
Protein Sequences

Strain Variation

Strain Sequence Variants (Rnor 6.0)
Damaging Variants

Additional Information

External Database Links
Nomenclature History
More on Hint1
Alliance Gene
Ensembl Gene
JBrowse: rn5 rn6
NCBI Genome Data Viewer

RGD Object Information
RGD ID: 1593411
Created: 2006-11-20
Species: Rattus norvegicus
Last Modified: 2020-06-09
Status: ACTIVE


RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.