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Gene: Hint1 (histidine triad nucleotide binding protein 1) Rattus norvegicus
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Symbol: Hint1
Name: histidine triad nucleotide binding protein 1
Description: Predicted to have hydrolase activity. Predicted to be involved in several processes, including intrinsic apoptotic signaling pathway by p53 class mediator; positive regulation of calcium-mediated signaling; and purine ribonucleotide catabolic process. Predicted to localize to cytosol; histone deacetylase complex; and plasma membrane. Human ortholog(s) of this gene implicated in Gamstorp-Wohlfart syndrome. Orthologous to human HINT1 (histidine triad nucleotide binding protein 1); INTERACTS WITH 2,3,7,8-tetrachlorodibenzodioxine; benzo[a]pyrene; bisphenol A.
Type: protein-coding
RefSeq Status: PROVISIONAL
Also known as: 17 kDa inhibitor of protein kinase C; adenosine 5'-monophosphoramidase; histidine triad nucleotide-binding protein 1; LOC690660; Pkci; PKCI-1; Prkci; protein kinase C inhibitor 1; protein kinase C, iota; protein kinase C-interacting protein 1; similar to Histidine triad nucleotide-binding protein 1 (Adenosine 5-monophosphoramidase) (Protein kinase C inhibitor 1) (Protein kinase C-interacting protein 1) (PKCI-1)
Orthologs:
Homo sapiens (human) : HINT1 (histidine triad nucleotide binding protein 1)  HGNC  Alliance
Mus musculus (house mouse) : Hint1 (histidine triad nucleotide binding protein 1)  MGI  Alliance
Chinchilla lanigera (long-tailed chinchilla) : Hint1 (histidine triad nucleotide binding protein 1)
Pan paniscus (bonobo/pygmy chimpanzee) : HINT1 (histidine triad nucleotide binding protein 1)
Canis lupus familiaris (dog) : HINT1 (histidine triad nucleotide binding protein 1)
Ictidomys tridecemlineatus (thirteen-lined ground squirrel) : Hint1 (histidine triad nucleotide binding protein 1)
Sus scrofa (pig) : HINT1 (histidine triad nucleotide binding protein 1)
Chlorocebus sabaeus (African green monkey) : HINT1 (histidine triad nucleotide binding protein 1)
Heterocephalus glaber (naked mole-rat) : Hint1 (histidine triad nucleotide binding protein 1)
more info ...
Related Pseudogenes: Hint1-ps1  
Latest Assembly: Rnor_6.0 - RGSC Genome Assembly v6.0
Position:
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Rnor_6.01040,208,236 - 40,211,981 (+)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl1040,208,223 - 40,211,975 (+)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.01039,980,504 - 39,984,249 (+)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.41040,271,895 - 40,275,640 (+)NCBIRGSC3.4rn4RGSC3.4
Celera1038,327,662 - 38,331,407 (+)NCBICelera
Cytogenetic Map10q22NCBI
JBrowse: View Region in Genome Browser (JBrowse)
Model


Disease Annotations
Gene-Chemical Interaction Annotations
Gene Ontology Annotations
References - curated
References - uncurated

Genomics

Comparative Map Data
Position Markers
QTLs in Region (Rnor_6.0)
miRNA Target Status

Expression

RNA-SEQ Expression

Sequence

Nucleotide Sequences
Protein Sequences
Transcriptome
Promoters

Strain Variation

Strain Sequence Variants (Rnor 6.0)
Damaging Variants

Additional Information

External Database Links
Nomenclature History
 
More on Hint1
Alliance Gene
NCBI Gene
Ensembl Gene
JBrowse: rn5 rn6
NCBI Genome Data Viewer

RGD Object Information
RGD ID: 1593411
Created: 2006-11-20
Species: Rattus norvegicus
Last Modified: 2020-06-09
Status: ACTIVE



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RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.