Submit Data |  Help |  Video Tutorials |  News |  Publications |  FTP Download |  REST API |  Citing RGD |  Contact   
Search RGD Grant Resources Citing RGD About Us Contact Us
Genes QTLs Strains Markers Genome Information Ontologies Cell Lines References FTP Download Submit Data
OntoMate (Literature Search) JBrowse (Genome Browser) Variant Visualizer Multi-Ontology Enrichment (MOET) Gene-Ortholog Location Finder (GOLF) InterViewer (Protein-Protein Interactions) PhenoMiner (Quatitative Phenotypes) Gene Annotator OLGA (Gene List Generator) RatMine GViewer (Genome Viewer) Overgo Probe Designer ACP Haplotyper Genome Scanner
Aging & Age-Related Disease Cancer Cardiovascular Disease Developmental Disease Diabetes Hematologic Disease Immune & Inflammatory Disease Neurological Disease Obesity & Metabolic Syndrome Renal Disease Respiratory Disease Sensory Organ Disease
Genetic Models PhenoMiner (Quantitative Phenotypes) Expected Ranges (Quantitative Phenotype) PhenoMiner Term Comparison Hybrid Rat Diversity Panel Phenotypes GERRC (Gene Editing Rat Resource Center) Phenotypes in Other Animal Models Animal Husbandry Strain Medical Records Phylogenetics Strain Availability Calendar Rats 101 Submissions Photo Archive
Pathways
Rat Community Forum Directory of Rat Laboratories Video Tutorials News RGD Publications RGD Poster Archive Nomenclature Guidelines Resource Links Laboratory Resources Employment Resources
Gene: Obscn (obscurin, cytoskeletal calmodulin and titin-interacting RhoGEF) Rattus norvegicus
Analyze
Symbol: Obscn
Name: obscurin, cytoskeletal calmodulin and titin-interacting RhoGEF
Description: Predicted to have several functions, including cadherin binding activity; cytoskeletal protein binding activity; and phosphatidylinositol phosphate binding activity. Predicted to be involved in negative regulation of phosphatidylinositol 3-kinase signaling and protein autophosphorylation. Localizes to the M band and Z disc. Orthologous to human OBSCN (obscurin, cytoskeletal calmodulin and titin-interacting RhoGEF); INTERACTS WITH acrylamide; ammonium chloride; atrazine.
Type: protein-coding
RefSeq Status: MODEL
Also known as: hypothetical LOC287353; LOC287353; Obscnl; obscurin; obscurin, cytoskeletal calmodulin and titin-interacting RhoGEF-like; RGD1305774
Orthologs:
Homo sapiens (human) : OBSCN (obscurin, cytoskeletal calmodulin and titin-interacting RhoGEF)  HGNC  Alliance
Mus musculus (house mouse) : Obscn (obscurin, cytoskeletal calmodulin and titin-interacting RhoGEF)  MGI  Alliance
Chinchilla lanigera (long-tailed chinchilla) : Obscn (obscurin, cytoskeletal calmodulin and titin-interacting RhoGEF)
Pan paniscus (bonobo/pygmy chimpanzee) : OBSCN (obscurin, cytoskeletal calmodulin and titin-interacting RhoGEF)
Canis lupus familiaris (dog) : OBSCN (obscurin, cytoskeletal calmodulin and titin-interacting RhoGEF)
Ictidomys tridecemlineatus (thirteen-lined ground squirrel) : LOC101962737 (obscurin)
Sus scrofa (pig) : OBSCN (obscurin, cytoskeletal calmodulin and titin-interacting RhoGEF)
more info ...
Latest Assembly: Rnor_6.0 - RGSC Genome Assembly v6.0
Position:
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Rnor_6.01045,353,185 - 45,483,570 (-)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl1045,338,009 - 45,481,008 (-)Ensembl
Rnor_5.01045,094,419 - 45,240,049 (-)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.41045,286,791 - 45,432,832 (-)NCBIRGSC3.4rn4RGSC3.4
Celera1043,040,464 - 43,184,409 (-)NCBICelera
Cytogenetic Map10q22NCBI
JBrowse: View Region in Genome Browser (JBrowse)
Model

Annotation    (Toggle Annotation Detail/Summary View)

Disease Annotations
Gene-Chemical Interaction Annotations
Gene Ontology Annotations
References - curated
References - uncurated

Genomics

Comparative Map Data
Position Markers
QTLs in Region (Rnor_6.0)
miRNA Target Status

Expression

RNA-SEQ Expression

Sequence

Nucleotide Sequences
Protein Sequences
Transcriptome

Strain Variation

Strain Sequence Variants (Rnor 6.0)
Damaging Variants

Additional Information

External Database Links
Nomenclature History
  
More on Obscn
Alliance Gene
NCBI Gene
Ensembl Gene
JBrowse: rn5 rn6
NCBI Genome Data Viewer

RGD Object Information
RGD ID: 631335
Created: 2003-08-13
Species: Rattus norvegicus
Last Modified: 2019-11-27
Status: ACTIVE



Contact Us |  About Us |  License CC BY 4.0 |  Legal Disclaimer |  © Medical College of Wisconsin
NHLBI Logo

RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.