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Gene: P4ha2 (prolyl 4-hydroxylase subunit alpha 2) Rattus norvegicus
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Symbol: P4ha2
Name: prolyl 4-hydroxylase subunit alpha 2
Description: Predicted to contribute to procollagen-proline 4-dioxygenase activity. Predicted to be involved in peptidyl-proline hydroxylation to 4-hydroxy-L-proline. Predicted to localize to the cytosol; nucleoplasm; and procollagen-proline 4-dioxygenase complex. Human ortholog(s) of this gene implicated in myopia. Orthologous to human P4HA2 (prolyl 4-hydroxylase subunit alpha 2); PARTICIPATES IN arginine and proline metabolic pathway; INTERACTS WITH (S)-10-[(DIMETHYLAMINO)METHYL]-4-ETHYL-4,9-DIHYDROXY-1H-PYRANO[3',4':6,7]INOLIZINO[1,2-B]-QUINOLINE-3,14(4H,12H)-DIONE; 2,3,7,8-tetrachlorodibenzodioxine; 2,4-dinitrotoluene.
Type: protein-coding
RefSeq Status: PROVISIONAL
Also known as: LOC360526; procollagen-proline, 2-oxoglutarate 4-dioxygenase (proline 4-hydroxylase), alpha II polypeptide; procollagen-proline, 2-oxoglutarate 4-dioxygenase (proline 4-hydroxylase), alpha polypeptide II; prolyl 4-hydroxylase subunit alpha-2; prolyl 4-hydroxylase, alpha polypeptide II
Orthologs:
Homo sapiens (human) : P4HA2 (prolyl 4-hydroxylase subunit alpha 2)  HGNC  Alliance
Mus musculus (house mouse) : P4ha2 (procollagen-proline, 2-oxoglutarate 4-dioxygenase (proline 4-hydroxylase), alpha II polypeptide)  MGI  Alliance
Chinchilla lanigera (long-tailed chinchilla) : P4ha2 (prolyl 4-hydroxylase subunit alpha 2)
Pan paniscus (bonobo/pygmy chimpanzee) : P4HA2 (prolyl 4-hydroxylase subunit alpha 2)
Canis lupus familiaris (dog) : P4HA2 (prolyl 4-hydroxylase subunit alpha 2)
Ictidomys tridecemlineatus (thirteen-lined ground squirrel) : P4ha2 (prolyl 4-hydroxylase subunit alpha 2)
Sus scrofa (pig) : P4HA2 (prolyl 4-hydroxylase subunit alpha 2)
more info ...
Latest Assembly: Rnor_6.0 - RGSC Genome Assembly v6.0
Position:
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Rnor_6.01039,435,227 - 39,464,134 (+)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_5.01039,214,791 - 39,243,698 (+)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.41039,522,157 - 39,551,063 (+)NCBIRGSC3.4rn4RGSC3.4
RGSC_v3.11039,535,833 - 39,564,271 (+)NCBI
Celera1037,584,460 - 37,613,368 (+)NCBICelera
Cytogenetic Map10q22NCBI
JBrowse: View Region in Genome Browser (JBrowse)
Model


Disease Annotations
Gene-Chemical Interaction Annotations
Gene Ontology Annotations
Molecular Pathway Annotations
References - curated
References - uncurated

Genomics

Comparative Map Data
Position Markers
QTLs in Region (Rnor_6.0)
miRNA Target Status

Sequence

Nucleotide Sequences
Protein Sequences
Transcriptome
Promoters

Strain Variation

Strain Sequence Variants (Rnor 5.0)
Damaging Variants

Additional Information

External Database Links
Nomenclature History
 
More on P4ha2
Alliance Gene
NCBI Gene
Ensembl Gene
JBrowse: rn5 rn6
NCBI Genome Data Viewer

RGD Object Information
RGD ID: 1309673
Created: 2005-01-12
Species: Rattus norvegicus
Last Modified: 2019-08-20
Status: ACTIVE



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RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.