Nmur2 (neuromedin U receptor 2) - Rat Genome Database

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Gene: Nmur2 (neuromedin U receptor 2) Rattus norvegicus
Analyze
Symbol: Nmur2
Name: neuromedin U receptor 2
RGD ID: 621155
Description: Enables neuropeptide receptor activity. Involved in regulation of sensory perception of pain. Predicted to be located in membrane. Predicted to be active in plasma membrane. Orthologous to human NMUR2 (neuromedin U receptor 2); INTERACTS WITH 17alpha-ethynylestradiol; alpha-Zearalanol; ammonium chloride.
Type: protein-coding
RefSeq Status: VALIDATED
Previously known as: FM-4; G-protein coupled receptor TGR-1; G-protein-coupled receptor FM-4; neuromedin-U receptor 2; NMU-R2; Nmu2r
RGD Orthologs
Human
Mouse
Chinchilla
Bonobo
Dog
Pig
Green Monkey
Naked Mole-Rat
Alliance Orthologs
More Info more info ...
Latest Assembly: mRatBN7.2 - mRatBN7.2 Assembly
Position:
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr81040,666,824 - 40,682,679 (-)NCBIGRCr8
mRatBN7.21040,166,223 - 40,182,078 (-)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl1040,166,226 - 40,182,078 (-)EnsemblmRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx1044,837,317 - 44,853,315 (-)NCBIRnor_SHRUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.01044,327,462 - 44,343,460 (-)NCBIRnor_SHRSPUTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.01039,831,122 - 39,847,120 (-)NCBIRnor_WKYUTH_Rnor_WKY_Bbb_1.0
Rnor_6.01041,392,663 - 41,408,518 (-)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl1041,392,666 - 41,408,518 (-)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.01041,219,613 - 41,235,468 (-)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.41041,471,179 - 41,485,043 (-)NCBIRGSC3.4RGSC_v3.4rn4RGSC3.4
RGSC_v3.11041,484,803 - 41,498,666 (-)NCBI
Celera1039,485,666 - 39,501,503 (-)NCBICelera
Cytogenetic Map10q22NCBI
JBrowse: View Region in Genome Browser (JBrowse)
Model


Disease Annotations     Click to see Annotation Detail View

Gene-Chemical Interaction Annotations     Click to see Annotation Detail View
Gene Ontology Annotations     Click to see Annotation Detail View

Cellular Component
membrane  (ISO)
plasma membrane  (IBA,IEA,ISO)

Molecular Function

References

References - curated
# Reference Title Reference Citation
1. Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium. Gaudet P, etal., Brief Bioinform. 2011 Sep;12(5):449-62. doi: 10.1093/bib/bbr042. Epub 2011 Aug 27.
2. Identification and functional characterization of a novel subtype of neuromedin U receptor. Hosoya M, etal., J Biol Chem 2000 Sep 22;275(38):29528-32.
3. Identification of receptors for neuromedin U and its role in feeding. Howard AD, etal., Nature 2000 Jul 6;406(6791):70-4.
4. Rat ISS GO annotations from MGI mouse gene data--August 2006 MGD data from the GO Consortium
5. Identification of neuromedin S and its possible role in the mammalian circadian oscillator system. Mori K, etal., EMBO J 2005 Jan 26;24(2):325-35. Epub 2005 Jan 6.
6. Electronic Transfer of LocusLink and RefSeq Data NCBI rat LocusLink and RefSeq merged data July 26, 2002
7. GOA pipeline RGD automated data pipeline
8. ClinVar Automated Import and Annotation Pipeline RGD automated import pipeline for ClinVar variants, variant-to-disease annotations and gene-to-disease annotations
9. Data Import for Chemical-Gene Interactions RGD automated import pipeline for gene-chemical interactions
10. Pro-nociceptive effects of neuromedin U in rat. Yu XH, etal., Neuroscience. 2003;120(2):467-74.
Additional References at PubMed
PMID:8889548   PMID:10899166   PMID:15631899   PMID:17030627   PMID:17110433   PMID:18180374   PMID:18698496   PMID:21296417   PMID:23423171   PMID:24269937   PMID:30227148   PMID:30914203  
PMID:31069918  


Genomics

Comparative Map Data
Nmur2
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr81040,666,824 - 40,682,679 (-)NCBIGRCr8
mRatBN7.21040,166,223 - 40,182,078 (-)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl1040,166,226 - 40,182,078 (-)EnsemblmRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx1044,837,317 - 44,853,315 (-)NCBIRnor_SHRUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.01044,327,462 - 44,343,460 (-)NCBIRnor_SHRSPUTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.01039,831,122 - 39,847,120 (-)NCBIRnor_WKYUTH_Rnor_WKY_Bbb_1.0
Rnor_6.01041,392,663 - 41,408,518 (-)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl1041,392,666 - 41,408,518 (-)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.01041,219,613 - 41,235,468 (-)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.41041,471,179 - 41,485,043 (-)NCBIRGSC3.4RGSC_v3.4rn4RGSC3.4
RGSC_v3.11041,484,803 - 41,498,666 (-)NCBI
Celera1039,485,666 - 39,501,503 (-)NCBICelera
Cytogenetic Map10q22NCBI
NMUR2
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh385152,391,546 - 152,405,279 (-)NCBIGRCh38GRCh38hg38GRCh38
GRCh38.p14 Ensembl5152,391,546 - 152,433,368 (-)EnsemblGRCh38hg38GRCh38
GRCh375151,771,107 - 151,784,840 (-)NCBIGRCh37GRCh37hg19GRCh37
Build 365151,751,302 - 151,765,017 (-)NCBINCBI36Build 36hg18NCBI36
Build 345151,751,302 - 151,765,017NCBI
Celera5147,846,463 - 147,860,200 (-)NCBICelera
Cytogenetic Map5q33.1NCBI
HuRef5146,910,244 - 146,923,981 (-)NCBIHuRef
CHM1_15151,203,649 - 151,217,384 (-)NCBICHM1_1
T2T-CHM13v2.05152,924,513 - 152,938,245 (-)NCBIT2T-CHM13v2.0
Nmur2
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm391155,915,816 - 55,931,813 (-)NCBIGRCm39GRCm39mm39
GRCm39 Ensembl1155,915,813 - 55,931,836 (-)EnsemblGRCm39 Ensembl
GRCm381156,024,990 - 56,040,987 (-)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl1156,024,987 - 56,041,010 (-)EnsemblGRCm38mm10GRCm38
MGSCv371155,838,492 - 55,854,489 (-)NCBIGRCm37MGSCv37mm9NCBIm37
MGSCv361155,868,413 - 55,884,410 (-)NCBIMGSCv36mm8
Celera1160,806,131 - 60,822,188 (-)NCBICelera
Cytogenetic Map11B1.3NCBI
cM Map1133.39NCBI
Nmur2
(Chinchilla lanigera - long-tailed chinchilla)
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0NW_0049554086,862,243 - 6,872,805 (-)NCBIChiLan1.0ChiLan1.0
NMUR2
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
NHGRI_mPanPan1-v24147,616,118 - 147,630,526 (-)NCBINHGRI_mPanPan1-v2
NHGRI_mPanPan15145,755,664 - 145,770,047 (-)NCBINHGRI_mPanPan1
Mhudiblu_PPA_v05147,811,260 - 147,825,659 (-)NCBIMhudiblu_PPA_v0Mhudiblu_PPA_v0panPan3
PanPan1.15153,813,004 - 153,826,791 (-)NCBIpanpan1.1PanPan1.1panPan2
PanPan1.1 Ensembl5153,811,055 - 153,827,176 (-)Ensemblpanpan1.1panPan2
NMUR2
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.1456,994,731 - 57,018,429 (+)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
CanFam3.1 Ensembl456,994,886 - 57,008,384 (+)EnsemblCanFam3.1canFam3CanFam3.1
Dog10K_Boxer_Tasha456,885,634 - 56,909,684 (+)NCBIDog10K_Boxer_Tasha
ROS_Cfam_1.0457,442,833 - 57,466,883 (+)NCBIROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl457,430,442 - 57,456,458 (+)EnsemblROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.1457,258,890 - 57,282,940 (+)NCBIUMICH_Zoey_3.1
UNSW_CanFamBas_1.0457,369,114 - 57,393,157 (+)NCBIUNSW_CanFamBas_1.0
UU_Cfam_GSD_1.0457,860,086 - 57,885,818 (+)NCBIUU_Cfam_GSD_1.0
NMUR2
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 Ensembl1670,659,563 - 70,673,347 (+)EnsemblSscrofa11.1susScr11Sscrofa11.1
Sscrofa11.11670,659,732 - 70,672,346 (+)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
Sscrofa10.21676,522,957 - 76,535,804 (+)NCBISscrofa10.2Sscrofa10.2susScr3
NMUR2
(Chlorocebus sabaeus - green monkey)
Green Monkey AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.12354,934,525 - 55,217,859 (-)NCBIChlSab1.1ChlSab1.1chlSab2
ChlSab1.1 Ensembl2354,933,683 - 54,948,055 (-)EnsemblChlSab1.1ChlSab1.1 EnsemblchlSab2
Vero_WHO_p1.0NW_02366603422,739,585 - 22,752,597 (+)NCBIVero_WHO_p1.0Vero_WHO_p1.0
Nmur2
(Heterocephalus glaber - naked mole-rat)
Naked Mole-Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla_female_1.0 EnsemblNW_00462473336,597,431 - 36,611,439 (+)EnsemblHetGla_female_1.0HetGla_female_1.0 EnsemblhetGla2
HetGla 1.0NW_00462473336,597,310 - 36,612,589 (+)NCBIHetGla_female_1.0HetGla 1.0hetGla2

Variants

.
Variants in Nmur2
151 total Variants
miRNA Target Status

Predicted Target Of
Summary Value
Count of predictions:35
Count of miRNA genes:30
Interacting mature miRNAs:34
Transcripts:ENSRNOT00000018967
Prediction methods:Miranda, Rnahybrid, Targetscan
Result types:miRGate_prediction

The detailed report is available here: Full Report CSV TAB Printer

miRNA Target Status data imported from miRGate (http://mirgate.bioinfo.cnio.es/).
For more information about miRGate, see PMID:25858286 or access the full paper here.


QTLs in Region (mRatBN7.2)
The following QTLs overlap with this region.    Full Report CSV TAB Printer Gviewer
RGD IDSymbolNameLODP ValueTraitSub TraitChrStartStopSpecies
61441Btemp1Thermal response to stress QTL 14body temperature trait (VT:0005535)core body temperature (CMO:0001036)103539245763642539Rat
9589136Insul27Insulin level QTL 2710.460.001blood insulin amount (VT:0001560)plasma insulin level (CMO:0000342)101147401056474010Rat
152025229Scl83Serum cholesterol level QTL 834.33blood cholesterol amount (VT:0000180)103571058068663659Rat
1578779Tcas10Tongue tumor susceptibility QTL 103.12tongue integrity trait (VT:0010553)number of squamous cell tumors of the tongue with diameter greater than 3 mm (CMO:0001950)103129743976297439Rat
631564Apr3Acute phase response QTL 33.9blood interleukin-6 amount (VT:0008595)plasma interleukin-6 level (CMO:0001927)101527595560275955Rat
1298069Bp168Blood pressure QTL 1685.5blood pressure trait (VT:0000183)systolic blood pressure (CMO:0000004)102652195798003205Rat
631554Bp133Blood pressure QTL 1330.005arterial blood pressure trait (VT:2000000)systolic blood pressure (CMO:0000004)1074336463851208Rat
631557Bp136Blood pressure QTL 1360.003arterial blood pressure trait (VT:2000000)systolic blood pressure (CMO:0000004)103063205375632053Rat
61325Aia5Adjuvant induced arthritis QTL 50.01joint integrity trait (VT:0010548)joint inflammation composite score (CMO:0000919)1023444813104060283Rat
1578761Stresp21Stress response QTL 213.3thymus mass (VT:0004954)thymus wet weight (CMO:0000855)10637574651375746Rat
2298544Neuinf9Neuroinflammation QTL 94.6nervous system integrity trait (VT:0010566)spinal cord complement component 1, q subcomponent, B chain mRNA level (CMO:0002126)10580199062146030Rat
61332Eau3Experimental allergic uveoretinitis QTL 30.004uvea integrity trait (VT:0010551)experimental autoimmune uveitis score (CMO:0001504)103449055945579777Rat
10401803Kidm50Kidney mass QTL 50kidney mass (VT:0002707)both kidneys wet weight (CMO:0000085)1041834445418344Rat
1554317Bmd4Bone mineral density QTL 49.40.0001lumbar vertebra mineral mass (VT:0010511)volumetric bone mineral density (CMO:0001553)101981604299406971Rat
1598852Anxrr19Anxiety related response QTL 195.07body movement coordination trait (VT:0005424)number of rearing movements in an experimental apparatus (CMO:0001752)101816784163167841Rat
1581497Esta1Estrogen-induced thymic atrophy QTL 1thymus mass (VT:0004954)thymus wet weight (CMO:0000855)102132980561345413Rat
2313095Bss62Bone structure and strength QTL 621.50.0001tibia size trait (VT:0100001)tibia midshaft cross-sectional area (CMO:0001717)10538701450387014Rat
724527Bp148Blood pressure QTL 1480.0001arterial blood pressure trait (VT:2000000)mean arterial blood pressure (CMO:0000009)102845313673453136Rat
1358897Stresp6Stress response QTL 64.170.022blood norepinephrine amount (VT:0005663)plasma norepinephrine level (CMO:0001010)103539226764155584Rat
1331762Rf40Renal function QTL 403.873kidney blood vessel physiology trait (VT:0100012)absolute change in renal vascular resistance (CMO:0001900)102929950464155584Rat
2300171Bmd58Bone mineral density QTL 584.90.0001lumbar vertebra mineral mass (VT:0010511)volumetric bone mineral density (CMO:0001553)102694462871944628Rat
61354Pia10Pristane induced arthritis QTL 100.01joint integrity trait (VT:0010548)joint inflammation composite score (CMO:0000919)1023444813104060283Rat
2301967Cm73Cardiac mass QTL 734.55heart left ventricle mass (VT:0007031)heart left ventricle weight to body weight ratio (CMO:0000530)101448701189062041Rat
2303118Mamtr7Mammary tumor resistance QTL 70.003mammary gland integrity trait (VT:0010552)mammary tumor growth rate (CMO:0000344)109658275104670812Rat
2313104Bss61Bone structure and strength QTL 610.90.0001tibia area (VT:1000281)tibia midshaft cross-sectional area (CMO:0001717)10538701450387014Rat
9590310Scort19Serum corticosterone level QTL 196.30.001blood corticosterone amount (VT:0005345)plasma corticosterone level (CMO:0001173)101147401056474010Rat
10402859Bp381Blood pressure QTL 3810.002arterial blood pressure trait (VT:2000000)mean arterial blood pressure (CMO:0000009)102760646872606468Rat
2316949Gluco60Glucose level QTL 603.7blood glucose amount (VT:0000188)blood glucose level (CMO:0000046)1014487011107057807Rat
6893352Bw100Body weight QTL 1000.330.6body mass (VT:0001259)body weight (CMO:0000012)11590666560906665Rat
724556Pur2Proteinuria QTL 25.5urine protein amount (VT:0005160)urine protein level (CMO:0000591)102242750090627625Rat
8662860Vetf10Vascular elastic tissue fragility QTL 10artery integrity trait (VT:0010639)number of ruptures of the internal elastic lamina of the abdominal aorta and iliac arteries (CMO:0002562)10615418273453136Rat
2313066Bss63Bone structure and strength QTL 631.40.0001tibia strength trait (VT:1000284)bone polar moment of inertia (CMO:0001558)10538701450387014Rat
2313064Bmd71Bone mineral density QTL 710.90.0001tibia mineral mass (VT:1000283)compact volumetric bone mineral density (CMO:0001730)10538701450387014Rat
70223Bp57Blood pressure QTL 575arterial blood pressure trait (VT:2000000)systolic blood pressure (CMO:0000004)10180676123Rat
1354587Kidm21Kidney mass QTL 213.3kidney mass (VT:0002707)right kidney wet weight (CMO:0000082)101502851360430477Rat
6893350Bw99Body weight QTL 990.870.16body mass (VT:0001259)body weight (CMO:0000012)11590666560906665Rat
2317043Aia7Adjuvant induced arthritis QTL 73.82joint integrity trait (VT:0010548)left rear ankle joint diameter (CMO:0002149)103756507982565079Rat
70224Eae3Experimental allergic encephalomyelitis QTL 34.1nervous system integrity trait (VT:0010566)experimental autoimmune encephalomyelitis incidence/prevalence measurement (CMO:0001046)102652195761345413Rat
2317042Aia20Adjuvant induced arthritis QTL 203.38joint integrity trait (VT:0010548)right rear ankle joint diameter (CMO:0002150)103756507982565079Rat
2313081Bss64Bone structure and strength QTL 641.30.0001tibia strength trait (VT:1000284)tibia total energy absorbed before break (CMO:0001736)10538701450387014Rat
1331791Cm31Cardiac mass QTL 313.84606heart mass (VT:0007028)heart wet weight (CMO:0000069)1029299504107211142Rat
2313087Bmd80Bone mineral density QTL 803.20.0001tibia mineral mass (VT:1000283)total volumetric bone mineral density (CMO:0001728)101960648364606483Rat
1354614Hpcl1Hepatic cholesterol level QTL 13.3liver cholesterol amount (VT:0010498)liver cholesterol level (CMO:0001597)103539226751793994Rat
631532Cm50Cardiac mass QTL 506.6heart mass (VT:0007028)calculated heart weight (CMO:0000073)101790711351786432Rat
1576319Cia29Collagen induced arthritis QTL 29joint integrity trait (VT:0010548)joint inflammation composite score (CMO:0000919)103397392178973921Rat
7411611Foco17Food consumption QTL 1718.70.001eating behavior trait (VT:0001431)feed conversion ratio (CMO:0001312)10142315980Rat
631267Cia20Collagen induced arthritis QTL 203.2joint integrity trait (VT:0010548)joint inflammation composite score (CMO:0000919)1023444813104060283Rat
1600371Mcs21Mammary carcinoma susceptibility QTL 213mammary gland integrity trait (VT:0010552)mammary tumor growth rate (CMO:0000344)102887565052200160Rat
1576308Schws1Schwannoma susceptibility QTL 10.0041nervous system integrity trait (VT:0010566)percentage of study population developing trigeminal nerve neurilemmomas during a period of time (CMO:0002017)1040035094102359817Rat
631269Cia22Collagen induced arthritis QTL 228.9joint integrity trait (VT:0010548)joint inflammation composite score (CMO:0000919)1040035094104060283Rat
631268Cia21Collagen induced arthritis QTL 213.1joint integrity trait (VT:0010548)joint inflammation composite score (CMO:0000919)1014487011104060283Rat
9590268Scort13Serum corticosterone level QTL 133.260.001blood corticosterone amount (VT:0005345)plasma corticosterone level (CMO:0001173)101147401056474010Rat
1576311Pia26Pristane induced arthritis QTL 26joint integrity trait (VT:0010548)joint inflammation composite score (CMO:0000919)103122402675632053Rat
631270Cia23Collagen induced arthritis QTL 233.9joint integrity trait (VT:0010548)joint inflammation composite score (CMO:0000919)1040035094104060283Rat
61427Cia16Collagen induced arthritis QTL 163.2joint integrity trait (VT:0010548)joint inflammation composite score (CMO:0000919)10635789696121100Rat
2292441Bp308Blood pressure QTL 308arterial blood pressure trait (VT:2000000)mean arterial blood pressure (CMO:0000009)102760646872606468Rat
2313055Bw96Body weight QTL 963.60.0001body mass (VT:0001259)body weight (CMO:0000012)101960648364606483Rat
631542Bp82Blood pressure QTL 826.8arterial blood pressure trait (VT:2000000)systolic blood pressure (CMO:0000004)102652195798952741Rat

Markers in Region
D10Got62  
Rat AssemblyChrPosition (strand)SourceJBrowse
mRatBN7.21040,173,747 - 40,173,901 (+)MAPPERmRatBN7.2
Rnor_6.01041,400,188 - 41,400,341NCBIRnor6.0
Rnor_5.01041,227,138 - 41,227,291UniSTSRnor5.0
RGSC_v3.41041,476,712 - 41,476,866RGDRGSC3.4
RGSC_v3.41041,476,713 - 41,476,866UniSTSRGSC3.4
RGSC_v3.11041,490,336 - 41,490,489RGD
Celera1039,493,187 - 39,493,340UniSTS
RH 3.4 Map10432.5RGD
RH 3.4 Map10432.5UniSTS
Cytogenetic Map10q22UniSTS
D10Got203  
Rat AssemblyChrPosition (strand)SourceJBrowse
mRatBN7.21040,180,373 - 40,180,612 (+)MAPPERmRatBN7.2
Rnor_6.01041,406,814 - 41,407,052NCBIRnor6.0
Rnor_5.01041,233,764 - 41,234,002UniSTSRnor5.0
RGSC_v3.41041,483,339 - 41,483,577UniSTSRGSC3.4
Celera1039,499,801 - 39,500,037UniSTS
Cytogenetic Map10q22UniSTS
RH144592  
Rat AssemblyChrPosition (strand)SourceJBrowse
mRatBN7.21040,172,903 - 40,173,058 (+)MAPPERmRatBN7.2
Rnor_6.01041,399,344 - 41,399,498NCBIRnor6.0
Rnor_5.01041,226,294 - 41,226,448UniSTSRnor5.0
RGSC_v3.41041,475,869 - 41,476,023UniSTSRGSC3.4
Celera1039,492,343 - 39,492,497UniSTS
RH 3.4 Map10428.5UniSTS
Cytogenetic Map10q22UniSTS
AU046743  
Rat AssemblyChrPosition (strand)SourceJBrowse
mRatBN7.21040,173,745 - 40,173,982 (+)MAPPERmRatBN7.2
Rnor_6.01041,400,186 - 41,400,422NCBIRnor6.0
Rnor_5.01041,227,136 - 41,227,372UniSTSRnor5.0
RGSC_v3.41041,476,711 - 41,476,947UniSTSRGSC3.4
Celera1039,493,185 - 39,493,421UniSTS
Cytogenetic Map10q22UniSTS
BM390633  
Rat AssemblyChrPosition (strand)SourceJBrowse
mRatBN7.21040,166,688 - 40,166,896 (+)MAPPERmRatBN7.2
Rnor_6.01041,393,129 - 41,393,336NCBIRnor6.0
Rnor_5.01041,220,079 - 41,220,286UniSTSRnor5.0
RGSC_v3.41041,469,654 - 41,469,861UniSTSRGSC3.4
Celera1039,486,132 - 39,486,339UniSTS
RH 3.4 Map10426.2UniSTS
Cytogenetic Map10q22UniSTS


Expression

RNA-SEQ Expression

alimentary part of gastrointestinal system
appendage
circulatory system
ectoderm
endocrine system
endoderm
exocrine system
hemolymphoid system
hepatobiliary system
integumental system
mesenchyme
mesoderm
nervous system
renal system
reproductive system
respiratory system
9 1 2 71 9 25 3 7 3 1 26 9 70 4 43 22

Sequence


Ensembl Acc Id: ENSRNOT00000018967   ⟹   ENSRNOP00000018967
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.2 Ensembl1040,166,226 - 40,182,078 (-)Ensembl
Rnor_6.0 Ensembl1041,392,666 - 41,408,518 (-)Ensembl
RefSeq Acc Id: NM_022275   ⟹   NP_071611
RefSeq Status: VALIDATED
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr81040,666,824 - 40,682,679 (-)NCBI
mRatBN7.21040,166,223 - 40,182,078 (-)NCBI
Rnor_6.01041,392,663 - 41,408,518 (-)NCBI
Rnor_5.01041,219,613 - 41,235,468 (-)NCBI
RGSC_v3.41041,471,179 - 41,485,043 (-)RGD
Celera1039,485,666 - 39,501,503 (-)NCBI
Sequence:
RefSeq Acc Id: XM_063269806   ⟹   XP_063125876
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr81040,666,824 - 40,682,673 (-)NCBI
Protein Sequences
Protein RefSeqs NP_071611 (Get FASTA)   NCBI Sequence Viewer  
  XP_063125876 (Get FASTA)   NCBI Sequence Viewer  
GenBank Protein AAF82756 (Get FASTA)   NCBI Sequence Viewer  
  BAB13722 (Get FASTA)   NCBI Sequence Viewer  
  EDM04491 (Get FASTA)   NCBI Sequence Viewer  
Ensembl Protein ENSRNOP00000018967.2
GenBank Protein Q9ESQ4 (Get FASTA)   NCBI Sequence Viewer  
RefSeq Acc Id: NP_071611   ⟸   NM_022275
- UniProtKB: Q9JIB1 (UniProtKB/Swiss-Prot),   Q9ESQ4 (UniProtKB/Swiss-Prot),   A0A8L2QAH3 (UniProtKB/TrEMBL),   A6HEN6 (UniProtKB/TrEMBL)
- Sequence:
Ensembl Acc Id: ENSRNOP00000018967   ⟸   ENSRNOT00000018967
RefSeq Acc Id: XP_063125876   ⟸   XM_063269806
- Peptide Label: isoform X1
- UniProtKB: Q9JIB1 (UniProtKB/Swiss-Prot),   Q9ESQ4 (UniProtKB/Swiss-Prot)
Protein Structures
Name Modeler Protein Id AA Range Protein Structure
AF-Q9ESQ4-F1-model_v2 AlphaFold Q9ESQ4 1-395 view protein structure

Transcriptome

eQTL   View at Phenogen
WGCNA   View at Phenogen
Tissue/Strain Expression   View at Phenogen


Additional Information

Database Acc Id Source(s)
AGR Gene RGD:621155 AgrOrtholog
BioCyc Gene G2FUF-25069 BioCyc
Ensembl Genes ENSRNOG00000014081 Ensembl, UniProtKB/TrEMBL
Ensembl Transcript ENSRNOT00000018967.4 UniProtKB/TrEMBL
Gene3D-CATH Rhodopsin 7-helix transmembrane proteins UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
InterPro GPCR_Rhodpsn UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  GPCR_Rhodpsn_7TM UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  NeuromedU_rcpt UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  NeuromedU_rcpt_2 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  NMU-R2_C UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
KEGG Report rno:64042 UniProtKB/Swiss-Prot
NCBI Gene 64042 ENTREZGENE
PANTHER G-PROTEIN COUPLED RECEPTOR UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  NEUROMEDIN-U RECEPTOR 2 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
Pfam 7tm_1 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  NmU-R2_C_term UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
PhenoGen Nmur2 PhenoGen
PRINTS GPCRRHODOPSN UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  NEUROMEDINUR UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  NEUROMEDNU2R UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
PROSITE G_PROTEIN_RECEP_F1_1 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  G_PROTEIN_RECEP_F1_2 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
RatGTEx ENSRNOG00000014081 RatGTEx
SMART 7TM_GPCR_Srsx UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
Superfamily-SCOP Family A G protein-coupled receptor-like UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
UniProt A0A8L2QAH3 ENTREZGENE, UniProtKB/TrEMBL
  A6HEN6 ENTREZGENE, UniProtKB/TrEMBL
  NMUR2_RAT UniProtKB/Swiss-Prot, ENTREZGENE
  Q9JIB1 ENTREZGENE
UniProt Secondary Q9JIB1 UniProtKB/Swiss-Prot


Nomenclature History
Date Current Symbol Current Name Previous Symbol Previous Name Description Reference Status
2004-09-10 Nmur2  neuromedin U receptor 2  Nmu2r    Symbol updated 1299863 APPROVED
2004-02-26 Nmu2r  neuromedin U receptor 2      Symbol and Name status set to approved 625702 APPROVED
2002-08-07 Nmu2r  neuromedin U receptor 2      Symbol and Name status set to provisional 70820 PROVISIONAL

RGD Curation Notes
Note Type Note Reference
gene_expression expressed in the ventromedial hypothalamus 632965