(+)-pilocarpine decreases expression EXP 6480464 Pilocarpine results in decreased expression of GRIA1 mRNA CTD PMID:7529610 (+)-pilocarpine increases expression EXP 6480464 Pilocarpine results in increased expression of GRIA1 protein CTD PMID:15857427 (S)-AMPA multiple interactions EXP 6480464 [alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid results in increased phosphorylation of KLC2 protein] inhibits the reaction [GRIA1 protein binds to KLC2 protein] CTD PMID:20534517 1-(4-methoxybenzyl)-3-(5-nitro-1,3-thiazol-2-yl)urea affects localization EXP 6480464 N-(4-methoxybenzyl)-N'-(5-nitro-1, 3-thiazol-2-yl)urea affects the localization of GRIA1 protein CTD PMID:20534517 1-[3-(dimethylamino)propyl]-1-(4-fluorophenyl)-1,3-dihydro-2-benzofuran-5-carbonitrile affects response to substance ISO RGD:731547 6480464 GRIA1 polymorphism affects the susceptibility to Citalopram CTD PMID:19295509 17beta-estradiol multiple interactions ISO RGD:731547 6480464 [Progesterone co-treated with 8-Bromo Cyclic Adenosine Monophosphate co-treated with Estradiol] results in decreased expression of GRIA1 mRNA more ... CTD PMID:23275455 2,2',4,4'-Tetrabromodiphenyl ether decreases expression ISO RGD:735685 6480464 2 more ... CTD PMID:17589592 2,2',4,4'-Tetrabromodiphenyl ether increases expression ISO RGD:731547 6480464 2 more ... CTD PMID:31173147 2,3,7,8-tetrachlorodibenzodioxine decreases expression EXP 6480464 Tetrachlorodibenzodioxin results in decreased expression of GRIA1 mRNA CTD PMID:16839606 , PMID:32109520 2,3,7,8-Tetrachlorodibenzofuran decreases expression EXP 6480464 2 more ... CTD PMID:32109520 2,3-Dioxo-6-nitro-7-sulfamoylbenzo(f)quinoxaline multiple interactions EXP 6480464 2, 3-dioxo-6-nitro-7-sulfamoylbenzo(f)quinoxaline inhibits the reaction [perfluorooctane sulfonic acid results in decreased expression of GRIA1 mRNA] CTD PMID:30508566 2-methyl-6-(phenylethynyl)pyridine multiple interactions EXP 6480464 6-methyl-2-(phenylethynyl)pyridine affects the reaction [Cocaine affects the phosphorylation of GRIA1 protein] CTD PMID:17680995 2-tert-butylhydroquinone increases expression ISO RGD:735685 6480464 2-tert-butylhydroquinone results in increased expression of GRIA1 mRNA CTD PMID:16014739 4-[1-hydroxy-2-[4-(phenylmethyl)-1-piperidinyl]propyl]phenol multiple interactions EXP 6480464 ifenprodil inhibits the reaction [Cocaine results in increased expression of GRIA1 protein] CTD PMID:19474322 6-Cyano-7-nitroquinoxaline-2,3-dione multiple interactions EXP 6480464 6-Cyano-7-nitroquinoxaline-2, 3-dione results in increased expression of and results in increased localization of GRIA1 protein CTD PMID:19674091 6-propyl-2-thiouracil decreases expression EXP 6480464 Propylthiouracil results in decreased expression of GRIA1 mRNA CTD PMID:24780913 8-Br-cAMP multiple interactions ISO RGD:731547 6480464 [Progesterone co-treated with 8-Bromo Cyclic Adenosine Monophosphate co-treated with Estradiol] results in decreased expression of GRIA1 mRNA more ... CTD PMID:23275455 acrylamide decreases expression EXP 6480464 Acrylamide results in decreased expression of GRIA1 mRNA CTD PMID:28959563 aflatoxin B1 decreases methylation ISO RGD:731547 6480464 Aflatoxin B1 results in decreased methylation of GRIA1 gene CTD PMID:27153756 all-trans-retinoic acid decreases expression ISO RGD:731547 6480464 Tretinoin results in decreased expression of GRIA1 mRNA CTD PMID:21934132 ammonium chloride affects expression EXP 6480464 Ammonium Chloride affects the expression of GRIA1 mRNA CTD PMID:16483693 arsenic acid decreases expression EXP 6480464 arsenic acid analog results in decreased expression of GRIA1 mRNA CTD PMID:19761793 arsenite(3-) decreases expression ISO RGD:735685 6480464 arsenite results in decreased expression of GRIA1 mRNA, arsenite results in decreased expression of GRIA1 protein CTD PMID:31708534 arsenous acid decreases expression ISO RGD:735685 6480464 Arsenic Trioxide results in decreased expression of GRIA1 mRNA CTD PMID:24831965 atrazine affects methylation EXP 6480464 Atrazine affects the methylation of GRIA1 gene CTD PMID:28931070 Bay-K-8644 increases phosphorylation ISO RGD:735685 6480464 3-Pyridinecarboxylic acid, 1 more ... CTD PMID:28194001 Bay-K-8644 increases expression ISO RGD:735685 6480464 3-Pyridinecarboxylic acid, 1 more ... CTD PMID:28194001 benzo[a]pyrene increases expression EXP 6480464 Benzo(a)pyrene results in increased expression of GRIA1 mRNA CTD PMID:21839799 , PMID:22108330 benzo[a]pyrene multiple interactions ISO RGD:731547 6480464 SNAP25 protein affects the reaction [Benzo(a)pyrene results in decreased expression of GRIA1 mRNA], SNAP25 protein affects the reaction [Benzo(a)pyrene results in decreased expression of GRIA1 protein] CTD PMID:28412278 benzo[a]pyrene decreases expression EXP 6480464 Benzo(a)pyrene results in decreased expression of GRIA1 mRNA, Benzo(a)pyrene results in decreased expression of GRIA1 protein CTD PMID:17606297 , PMID:28412278 benzo[a]pyrene decreases expression ISO RGD:731547 6480464 Benzo(a)pyrene results in decreased expression of GRIA1 mRNA, Benzo(a)pyrene results in decreased expression of GRIA1 protein CTD PMID:28412278 benzoates multiple interactions EXP 6480464 Benzoates analog binds to and results in decreased activity of GRIA1 protein CTD PMID:14667236 beta-naphthoflavone multiple interactions EXP 6480464 [Diethylnitrosamine co-treated with beta-Naphthoflavone] results in increased expression of GRIA1 mRNA CTD PMID:18164116 bicuculline multiple interactions EXP 6480464 Bicuculline results in decreased expression of and results in decreased localization of GRIA1 protein CTD PMID:19674091 bis(2-chloroethyl) sulfide decreases expression ISO RGD:735685 6480464 Mustard Gas results in decreased expression of GRIA1 mRNA CTD PMID:15674843 bis(2-ethylhexyl) phthalate decreases expression ISO RGD:731547 6480464 Diethylhexyl Phthalate results in decreased expression of GRIA1 mRNA CTD PMID:31163220 bisphenol A decreases expression EXP 6480464 bisphenol A results in decreased expression of GRIA1 mRNA, bisphenol A results in decreased expression of GRIA1 protein CTD PMID:24820113 more ... bisphenol A increases methylation EXP 6480464 bisphenol A results in increased methylation of GRIA1 gene CTD PMID:28505145 bisphenol A decreases expression ISO RGD:735685 6480464 bisphenol A results in decreased expression of GRIA1 protein CTD PMID:23240141 more ... calcium atom multiple interactions EXP 6480464 Calcium deficiency inhibits the reaction [Excitatory Amino Acid Agonists results in decreased phosphorylation of GRIA1 protein] CTD PMID:28404816 calcium(0) multiple interactions EXP 6480464 Calcium deficiency inhibits the reaction [Excitatory Amino Acid Agonists results in decreased phosphorylation of GRIA1 protein] CTD PMID:28404816 capsaicin increases phosphorylation EXP 6480464 Capsaicin results in increased phosphorylation of GRIA1 protein CTD PMID:12019337 capsaicin multiple interactions EXP 6480464 KN 93 inhibits the reaction [Capsaicin results in increased phosphorylation of GRIA1 protein] CTD PMID:12019337 carbon nanotube decreases expression ISO RGD:735685 6480464 Nanotubes, Carbon analog results in decreased expression of GRIA1 mRNA, Nanotubes, Carbon results in decreased expression of GRIA1 mRNA CTD PMID:25554681 celecoxib multiple interactions ISO RGD:735685 6480464 Celecoxib promotes the reaction [Kainic Acid results in decreased expression of GRIA1 mRNA] CTD PMID:21589914 chlorpyrifos increases expression EXP 6480464 Chlorpyrifos results in increased expression of GRIA1 mRNA CTD PMID:19440498 citalopram affects response to substance ISO RGD:731547 6480464 GRIA1 polymorphism affects the susceptibility to Citalopram CTD PMID:19295509 Citreoviridin decreases expression ISO RGD:735685 6480464 citreoviridin results in decreased expression of GRIA1 mRNA CTD PMID:30071239 cocaine multiple interactions EXP 6480464 6-methyl-2-(phenylethynyl)pyridine affects the reaction [Cocaine affects the phosphorylation of GRIA1 protein] more ... CTD PMID:11268215 more ... cocaine decreases expression EXP 6480464 Cocaine results in decreased expression of GRIA1 mRNA, Cocaine results in decreased expression of GRIA1 protein CTD PMID:24810662 cocaine increases phosphorylation ISO RGD:735685 6480464 Cocaine results in increased phosphorylation of GRIA1 protein CTD PMID:16473939 , PMID:23499958 cocaine increases phosphorylation EXP 6480464 Cocaine results in increased phosphorylation of GRIA1 protein CTD PMID:16794574 , PMID:19629758 cocaine affects response to substance EXP 6480464 GRIA1 protein affects the susceptibility to Cocaine CTD PMID:11801363 , PMID:18430032 cocaine affects expression EXP 6480464 Cocaine affects the expression of GRIA1 mRNA, Cocaine affects the expression of GRIA1 protein CTD PMID:12511956 more ... cocaine multiple interactions ISO RGD:735685 6480464 Cocaine results in increased expression of and results in increased phosphorylation of GRIA1 protein more ... CTD PMID:16473939 more ... cocaine affects expression ISO RGD:735685 6480464 Cocaine affects the expression of GRIA1 mRNA CTD PMID:9886066 cocaine increases expression ISO RGD:735685 6480464 Cocaine results in increased expression of GRIA1 protein CTD PMID:19070590 cocaine decreases response to substance ISO RGD:735685 6480464 GRIA1 results in decreased susceptibility to Cocaine CTD PMID:18701074 cocaine increases response to substance EXP 6480464 GRIA1 protein results in increased susceptibility to Cocaine CTD PMID:14684464 cocaine decreases response to substance EXP 6480464 GRIA1 protein mutant form results in decreased susceptibility to Cocaine, GRIA1 results in decreased susceptibility to Cocaine CTD PMID:12511956 , PMID:14684464 cocaine increases expression EXP 6480464 Cocaine results in increased expression of GRIA1 mRNA, Cocaine results in increased expression of GRIA1 protein CTD PMID:11801363 more ... cocaine decreases phosphorylation EXP 6480464 Cocaine results in decreased phosphorylation of GRIA1 protein CTD PMID:11268215 cypermethrin affects expression ISO RGD:735685 6480464 cypermethrin affects the expression of GRIA1 protein CTD PMID:26143737 decabromodiphenyl ether decreases expression EXP 6480464 decabromobiphenyl ether results in decreased expression of GRIA1 protein, decabromobiphenyl ether results in decreased expression of GRIA1 protein modified form CTD PMID:30404998 Diacetoxyscirpenol increases expression ISO RGD:735685 6480464 diacetoxyscirpenol results in increased expression of GRIA1 mRNA CTD PMID:31836554 diarsenic trioxide decreases expression ISO RGD:735685 6480464 Arsenic Trioxide results in decreased expression of GRIA1 mRNA CTD PMID:24831965 diazinon decreases expression EXP 6480464 Diazinon results in decreased expression of GRIA1 mRNA CTD PMID:17452286 diazinon increases expression EXP 6480464 Diazinon results in increased expression of GRIA1 mRNA CTD PMID:19440498 dichloroacetic acid decreases expression ISO RGD:735685 6480464 Dichloroacetic Acid results in decreased expression of GRIA1 mRNA CTD PMID:28962523 dieldrin increases expression EXP 6480464 Dieldrin results in increased expression of GRIA1 mRNA CTD PMID:19440498 domoic acid increases phosphorylation EXP 6480464 domoic acid results in increased phosphorylation of GRIA1 protein CTD PMID:19564213 dopamine increases localization EXP 6480464 Dopamine results in increased localization of GRIA1 protein CTD PMID:19674091 dorsomorphin multiple interactions ISO RGD:731547 6480464 [NOG protein co-treated with entinostat co-treated with dorsomorphin co-treated with 4-(5-benzo(1 more ... CTD PMID:27188386 doxorubicin increases expression ISO RGD:731547 6480464 Doxorubicin results in increased expression of GRIA1 mRNA CTD PMID:30031762 endosulfan increases expression ISO RGD:735685 6480464 Endosulfan results in increased expression of GRIA1 protein CTD PMID:26143737 entinostat multiple interactions ISO RGD:731547 6480464 [NOG protein co-treated with entinostat co-treated with dorsomorphin co-treated with 4-(5-benzo(1, 3)dioxol-5-yl-4-pyridin-2-yl-1H-imidazol-2-yl)benzamide] results in decreased expression of GRIA1 mRNA CTD PMID:27188386 entinostat decreases expression ISO RGD:731547 6480464 entinostat results in decreased expression of GRIA1 mRNA CTD PMID:26272509 ethanol decreases expression EXP 6480464 Ethanol results in decreased expression of GRIA1 mRNA CTD PMID:20655511 ethanol multiple interactions ISO RGD:735685 6480464 Ethanol affects the expression of and affects the splicing of GRIA1 mRNA CTD PMID:30319688 excitatory amino acid agonist multiple interactions EXP 6480464 Calcium deficiency inhibits the reaction [Excitatory Amino Acid Agonists results in decreased phosphorylation of GRIA1 protein] CTD PMID:28404816 excitatory amino acid agonist decreases phosphorylation EXP 6480464 Excitatory Amino Acid Agonists results in decreased phosphorylation of GRIA1 protein CTD PMID:28404816 flavonoids decreases expression EXP 6480464 Flavonoids results in decreased expression of GRIA1 mRNA CTD PMID:18035473 fluoxetine affects expression EXP 6480464 Fluoxetine affects the expression of GRIA1 protein CTD PMID:20417256 fluoxetine affects phosphorylation ISO RGD:735685 6480464 Fluoxetine affects the phosphorylation of GRIA1 protein CTD PMID:11880651 fluoxetine multiple interactions ISO RGD:735685 6480464 PPP1R1B protein promotes the reaction [Fluoxetine affects the phosphorylation of GRIA1 protein] CTD PMID:11880651 genistein decreases expression EXP 6480464 Genistein results in decreased expression of GRIA1 mRNA CTD PMID:21782745 genistein increases expression ISO RGD:735685 6480464 Genistein results in increased expression of GRIA1 mRNA CTD PMID:32186404 glycine multiple interactions EXP 6480464 Glycine results in increased expression of and results in increased phosphorylation of GRIA1 protein, HNRNPK mutant form inhibits the reaction [Glycine results in increased expression of and results in increased phosphorylation of GRIA1 protein] CTD PMID:24990929 haloperidol decreases expression EXP 6480464 Haloperidol results in decreased expression of GRIA1 mRNA CTD PMID:15860345 istradefylline multiple interactions EXP 6480464 istradefylline inhibits the reaction [Levodopa affects the phosphorylation of GRIA1 protein] CTD PMID:14637099 kainic acid multiple interactions EXP 6480464 2-(2-(4-(4-nitrobenzyloxy)phenyl)ethyl)isothiourea methanesulfonate inhibits the reaction [Kainic Acid results in decreased expression of GRIA1 protein] more ... CTD PMID:11812690 , PMID:17585341 kainic acid decreases expression ISO RGD:735685 6480464 Kainic Acid results in decreased expression of GRIA1 mRNA CTD PMID:21589914 kainic acid multiple interactions ISO RGD:735685 6480464 Celecoxib promotes the reaction [Kainic Acid results in decreased expression of GRIA1 mRNA], PTGS2 affects the reaction [Kainic Acid results in decreased expression of GRIA1 mRNA] CTD PMID:21589914 kainic acid decreases expression EXP 6480464 Kainic Acid results in decreased expression of GRIA1 mRNA, Kainic Acid results in decreased expression of GRIA1 protein CTD PMID:17585341 , PMID:7529610 ketamine decreases expression ISO RGD:735685 6480464 Ketamine results in decreased expression of GRIA1 protein CTD PMID:31470060 ketamine multiple interactions ISO RGD:735685 6480464 MAPT protein affects the reaction [Ketamine results in decreased expression of GRIA1 protein] CTD PMID:31470060 KN-93 multiple interactions EXP 6480464 KN 93 inhibits the reaction [Capsaicin results in increased phosphorylation of GRIA1 protein] CTD PMID:12019337 lactacystin increases localization EXP 6480464 lactacystin results in increased localization of GRIA1 protein CTD PMID:19674091 lead diacetate affects expression ISO RGD:735685 6480464 lead acetate affects the expression of GRIA1 mRNA CTD PMID:24260418 lead(0) affects splicing ISO RGD:731547 6480464 Lead affects the splicing of GRIA1 mRNA CTD PMID:28903495 lead(0) multiple interactions EXP 6480464 [Lead co-treated with Tetrodotoxin] results in increased expression of [GRIA1 protein binds to GRIA2 protein] CTD PMID:29939358 lead(2+) affects splicing ISO RGD:731547 6480464 Lead affects the splicing of GRIA1 mRNA CTD PMID:28903495 lead(2+) multiple interactions EXP 6480464 [Lead co-treated with Tetrodotoxin] results in increased expression of [GRIA1 protein binds to GRIA2 protein] CTD PMID:29939358 lithium atom decreases expression EXP 6480464 Lithium results in decreased expression of GRIA1 protein CTD PMID:18171924 lithium hydride decreases expression EXP 6480464 Lithium results in decreased expression of GRIA1 protein CTD PMID:18171924 maleic acid increases expression ISO RGD:731547 6480464 maleic acid results in increased expression of GRIA1 mRNA CTD PMID:28392987 methamphetamine affects expression EXP 6480464 Methamphetamine affects the expression of GRIA1 mRNA CTD PMID:18419818 methylmercury chloride decreases expression ISO RGD:731547 6480464 methylmercuric chloride results in decreased expression of GRIA1 mRNA CTD PMID:28001369 mifepristone decreases expression ISO RGD:731547 6480464 Mifepristone results in decreased expression of GRIA1 mRNA CTD PMID:17584828 minocycline multiple interactions EXP 6480464 Minocycline inhibits the reaction [Poly C results in increased expression of GRIA1 mRNA] CTD PMID:19660546 morphine multiple interactions EXP 6480464 Morphine promotes the reaction [CREB1 protein modified form binds to GRIA1 promoter] CTD PMID:25643298 morphine increases expression EXP 6480464 Morphine results in increased expression of GRIA1 mRNA CTD PMID:15183518 morphine decreases expression EXP 6480464 Morphine results in decreased expression of GRIA1 mRNA, Morphine results in decreased expression of GRIA1 protein CTD PMID:15183518 , PMID:23711322 morphine decreases phosphorylation EXP 6480464 Morphine results in decreased phosphorylation of GRIA1 protein CTD PMID:15287884 morphine affects response to substance ISO RGD:735685 6480464 GRIA1 protein affects the susceptibility to Morphine CTD PMID:11404432 N-benzyloxycarbonyl-L-leucyl-L-leucyl-L-leucinal increases localization EXP 6480464 benzyloxycarbonylleucyl-leucyl-leucine aldehyde results in increased localization of GRIA1 protein CTD PMID:19674091 N-nitrosodiethylamine multiple interactions EXP 6480464 [Diethylnitrosamine co-treated with beta-Naphthoflavone] results in increased expression of GRIA1 mRNA CTD PMID:18164116 nickel atom increases expression EXP 6480464 Nickel results in increased expression of GRIA1 mRNA CTD PMID:19440498 nifedipine multiple interactions ISO RGD:735685 6480464 Nifedipine inhibits the reaction [Cocaine results in increased expression of and results in increased phosphorylation of GRIA1 protein] CTD PMID:28194001 ochratoxin A increases expression EXP 6480464 ochratoxin A results in increased expression of GRIA1 mRNA CTD PMID:27346841 Ondansetron multiple interactions EXP 6480464 Ondansetron inhibits the reaction [Cocaine results in increased phosphorylation of GRIA1 protein] CTD PMID:16794574 panobinostat multiple interactions ISO RGD:731547 6480464 [NOG protein co-treated with Panobinostat co-treated with dorsomorphin co-treated with 4-(5-benzo(1, 3)dioxol-5-yl-4-pyridin-2-yl-1H-imidazol-2-yl)benzamide] results in decreased expression of GRIA1 mRNA CTD PMID:27188386 perfluorooctane-1-sulfonic acid multiple interactions EXP 6480464 2 more ... CTD PMID:30508566 perfluorooctane-1-sulfonic acid decreases expression EXP 6480464 perfluorooctane sulfonic acid results in decreased expression of GRIA1 mRNA CTD PMID:30508566 pirinixic acid increases expression ISO RGD:735685 6480464 pirinixic acid results in increased expression of GRIA1 mRNA CTD PMID:20813756 poly(cytidylic acid) increases expression EXP 6480464 Poly C results in increased expression of GRIA1 mRNA CTD PMID:19660546 poly(cytidylic acid) multiple interactions EXP 6480464 Minocycline inhibits the reaction [Poly C results in increased expression of GRIA1 mRNA] CTD PMID:19660546 progesterone increases expression ISO RGD:731547 6480464 Progesterone results in increased expression of GRIA1 mRNA CTD PMID:21795739 progesterone multiple interactions ISO RGD:731547 6480464 [Progesterone co-treated with 8-Bromo Cyclic Adenosine Monophosphate co-treated with Estradiol] results in decreased expression of GRIA1 mRNA more ... CTD PMID:23275455 resveratrol multiple interactions ISO RGD:735685 6480464 resveratrol promotes the reaction [Cocaine results in increased phosphorylation of GRIA1 protein] CTD PMID:23499958 rifampicin decreases expression ISO RGD:731547 6480464 Rifampin results in decreased expression of GRIA1 mRNA CTD PMID:24552687 SB 431542 multiple interactions ISO RGD:731547 6480464 [NOG protein co-treated with entinostat co-treated with dorsomorphin co-treated with 4-(5-benzo(1 more ... CTD PMID:27188386 sevoflurane increases expression ISO RGD:735685 6480464 Sevoflurane results in increased expression of GRIA1 protein CTD PMID:30502404 SL-327 multiple interactions ISO RGD:735685 6480464 SL 327 inhibits the reaction [Cocaine results in increased phosphorylation of GRIA1 protein] CTD PMID:16473939 sodium arsenate increases expression ISO RGD:735685 6480464 sodium arsenate results in increased expression of GRIA1 mRNA CTD PMID:21795629 sodium arsenite decreases response to substance ISO RGD:735685 6480464 GRIA1 protein results in decreased susceptibility to sodium arsenite CTD PMID:23694735 sodium arsenite decreases expression ISO RGD:735685 6480464 sodium arsenite results in decreased expression of GRIA1 protein CTD PMID:29204679 sodium arsenite affects methylation ISO RGD:731547 6480464 sodium arsenite affects the methylation of GRIA1 gene CTD PMID:28589171 sodium arsenite affects expression ISO RGD:735685 6480464 sodium arsenite affects the expression of GRIA1 protein CTD PMID:23694735 sulfur dioxide decreases expression EXP 6480464 Sulfur Dioxide results in decreased expression of GRIA1 mRNA CTD PMID:25534910 tadalafil multiple interactions ISO RGD:735685 6480464 Tadalafil inhibits the reaction [Thioacetamide results in decreased expression of GRIA1 protein] CTD PMID:31323263 tetrachloromethane affects expression EXP 6480464 Carbon Tetrachloride affects the expression of GRIA1 mRNA CTD PMID:12734012 tetrodotoxin increases localization EXP 6480464 Tetrodotoxin results in increased localization of GRIA1 protein CTD PMID:19674091 tetrodotoxin multiple interactions EXP 6480464 [Lead co-treated with Tetrodotoxin] results in increased expression of [GRIA1 protein binds to GRIA2 protein] CTD PMID:29939358 thioacetamide decreases expression ISO RGD:735685 6480464 Thioacetamide results in decreased expression of GRIA1 protein CTD PMID:31323263 thioacetamide multiple interactions ISO RGD:735685 6480464 Tadalafil inhibits the reaction [Thioacetamide results in decreased expression of GRIA1 protein] CTD PMID:31323263 titanium dioxide decreases expression ISO RGD:735685 6480464 titanium dioxide results in decreased expression of GRIA1 mRNA CTD PMID:23557971 triazolam decreases expression ISO RGD:735685 6480464 Triazolam results in decreased expression of GRIA1 protein CTD PMID:27489535 tributylstannane decreases expression EXP 6480464 tributyltin results in decreased expression of GRIA1 mRNA CTD PMID:19591855 trichostatin A increases expression ISO RGD:731547 6480464 trichostatin A results in increased expression of GRIA1 mRNA CTD PMID:24935251 trichostatin A multiple interactions ISO RGD:731547 6480464 [NOG protein co-treated with trichostatin A co-treated with dorsomorphin co-treated with 4-(5-benzo(1, 3)dioxol-5-yl-4-pyridin-2-yl-1H-imidazol-2-yl)benzamide] results in decreased expression of GRIA1 mRNA CTD PMID:27188386 trichostatin A decreases expression ISO RGD:731547 6480464 trichostatin A results in decreased expression of GRIA1 mRNA CTD PMID:26272509 urethane multiple interactions EXP 6480464 Urethane inhibits the reaction [Kainic Acid binds to and results in increased activity of GRIA1 protein] CTD PMID:11812690 valproic acid decreases expression EXP 6480464 Valproic Acid results in decreased expression of GRIA1 protein CTD PMID:18171924 valproic acid increases expression EXP 6480464 Valproic Acid results in increased expression of GRIA1 mRNA CTD PMID:31085223 valproic acid decreases expression ISO RGD:731547 6480464 Valproic Acid results in decreased expression of GRIA1 mRNA CTD PMID:28001369 valproic acid increases expression ISO RGD:731547 6480464 Valproic Acid results in increased expression of GRIA1 mRNA CTD PMID:23179753 , PMID:27188386 valproic acid decreases expression ISO RGD:735685 6480464 Valproic Acid results in decreased expression of GRIA1 mRNA CTD PMID:24896083 valproic acid affects expression ISO RGD:731547 6480464 Valproic Acid affects the expression of GRIA1 mRNA CTD PMID:25979313 valproic acid decreases methylation ISO RGD:731547 6480464 Valproic Acid results in decreased methylation of GRIA1 gene CTD PMID:29154799 venlafaxine hydrochloride increases expression EXP 6480464 Venlafaxine Hydrochloride results in increased expression of GRIA1 mRNA CTD PMID:25423262 vorinostat decreases expression ISO RGD:731547 6480464 vorinostat results in decreased expression of GRIA1 mRNA CTD PMID:26272509 WIN 55212-2 decreases expression EXP 6480464 Win 55212-2 results in decreased expression of GRIA1 protein CTD PMID:32312805
Biological Process cellular response to amine stimulus IEP 4107725 dopamine RGD cellular response to amino acid stimulus IEP 4107720 glutamate RGD cellular response to dsRNA IEP 2325933 miR-132 RGD cellular response to growth factor stimulus IEP 2325933 BDNF RGD cellular response to organic cyclic compound IEP 4107360 sigma-1 receptor agonist SA4503 RGD cellular response to peptide hormone stimulus IEP 4107071 leptin RGD chemical synaptic transmission IEA UniProtKB:P23818 , ensembl:ENSMUSP000000444941600115 GO_REF:0000107 Ensembl GO_REF:0000107 chemical synaptic transmission ISO RGD:735685 1624291 MGI:MGI:1201678 (MGI:MGI:4353919 , PMID:19657020) RGD MGI:MGI:4353919 , PMID:19657020 ion transmembrane transport IEA GO:0005216 1600115 GO_REF:0000108 GOC GO_REF:0000108 ion transmembrane transport IEA GO:0015276 1600115 GO_REF:0000108 GOC GO_REF:0000108 ionotropic glutamate receptor signaling pathway IEA GO:0004970 1600115 GO_REF:0000108 GOC GO_REF:0000108 ionotropic glutamate receptor signaling pathway IEA GO:0004971 1600115 GO_REF:0000108 GOC GO_REF:0000108 long-term memory IMP 4107728 RGD long-term memory IEA UniProtKB:P23818 , ensembl:ENSMUSP000000444941600115 GO_REF:0000107 Ensembl GO_REF:0000107 long-term memory ISO RGD:735685 1624291 (MGI:MGI:2653003, PMID:12628184) RGD MGI:MGI:2653003 , PMID:12628184 long-term synaptic depression ISO RGD:735685 1624291 MGI:MGI:99401 (MGI:MGI:5529732 , PMID:24259587) RGD MGI:MGI:5529732 , PMID:24259587 long-term synaptic depression IEA UniProtKB:P23818 , ensembl:ENSMUSP000000444941600115 GO_REF:0000107 Ensembl GO_REF:0000107 modulation of chemical synaptic transmission IDA 8553683 PMID:11348590 UniProt neuronal action potential IMP 8553676 PMID:12536214 UniProt positive regulation of membrane potential IMP 4107350 RGD positive regulation of synaptic transmission IMP 8553683 PMID:11348590 UniProt receptor internalization IDA 8554168 PMID:11100149 UniProt receptor internalization IEA UniProtKB:P23818 , ensembl:ENSMUSP000000444941600115 GO_REF:0000107 Ensembl GO_REF:0000107 receptor internalization ISO RGD:735685 1624291 (MGI:MGI:2653003, PMID:12628184) RGD MGI:MGI:2653003 , PMID:12628184 regulation of postsynaptic cytosolic calcium ion concentration IEA GO:0099583 1600115 GO_REF:0000108 GOC GO_REF:0000108 regulation of postsynaptic membrane potential ISO RGD:735685 1624291 (MGI:MGI:2178282, PMID:11431570) RGD MGI:MGI:2178282 , PMID:11431570 regulation of postsynaptic membrane potential IEA UniProtKB:P23818 , ensembl:ENSMUSP000000444941600115 GO_REF:0000107 Ensembl GO_REF:0000107 regulation of receptor recycling IMP 8553683 PMID:11348590 UniProt regulation of synaptic plasticity IMP 8553676 PMID:12536214 UniProt regulation of synaptic plasticity NAS 8553901 PMID:15269270 UniProt response to arsenic-containing substance IEP 4107724 RGD response to cocaine IEP 4107066 RGD response to drug IEP 4107717 heroin RGD response to electrical stimulus IEP 7175067 RGD response to estradiol IEP 4107727 RGD response to fungicide IEP 2325972 tributyltin RGD response to lithium ion IEP 8553901 PMID:15269270 UniProt response to organic cyclic compound IEP 4107717 cannabidiol RGD response to peptide hormone IEP 4107067 melanin-concentrating hormone RGD response to toxic substance IMP 4107350 alloxan RGD spinal cord development IEP 2325980 RGD synaptic transmission, glutamatergic NAS 8553901 PMID:15269270 UniProt Cellular Component AMPA glutamate receptor complex IDA 8554136 PMID:19265014 UniProt AMPA glutamate receptor complex IBA MGI:MGI:95808 more ... 13792537 PMID:21873635 GO_Central AMPA glutamate receptor complex IEA UniProtKB:P23818 , ensembl:ENSMUSP000000444941600115 GO_REF:0000107 Ensembl GO_REF:0000107 AMPA glutamate receptor complex ISO RGD:735685 1624291 (MGI:MGI:3587474 more ... RGD MGI:MGI:3587474 more ... asymmetric synapse IDA 1600985 RGD axonal spine ISO RGD:735685 1624291 (MGI:MGI:5469914, PMID:23303939) RGD MGI:MGI:5469914 , PMID:23303939 axonal spine IEA UniProtKB:P23818 , ensembl:ENSMUSP000000444941600115 GO_REF:0000107 Ensembl GO_REF:0000107 cell surface IDA 7242711 RGD cell surface ISO RGD:735685 1624291 (MGI:MGI:3765383 more ... RGD MGI:MGI:3765383 more ... cell surface IEA UniProtKB:P23818 , ensembl:ENSMUSP000000444941600115 GO_REF:0000107 Ensembl GO_REF:0000107 cell-cell junction IDA 11085699 PMID:26595655 UniProt cytosol IDA 4107350 RGD dendrite IDA 12907563 PMID:20032460 ARUK-UCL dendrite ISO RGD:735685 1624291 (MGI:MGI:4879039 more ... RGD MGI:MGI:4879039 more ... dendrite ISS UniProtKB:P23818 1600115 GO_REF:0000024 UniProt GO_REF:0000024 dendrite membrane ISO RGD:735685 1624291 (MGI:MGI:5320264, PMID:21795692) RGD MGI:MGI:5320264 , PMID:21795692 dendritic shaft IDA 1600985 RGD dendritic shaft IDA 8554168 PMID:11100149 UniProt dendritic spine IDA 1600985 ; 2312658 RGD dendritic spine IBA MGI:MGI:95808 more ... 13792537 PMID:21873635 GO_Central dendritic spine ISO RGD:735685 1624291 (MGI:MGI:4879039 more ... RGD MGI:MGI:4879039 more ... dendritic spine IDA 12907563 PMID:20032460 ARUK-UCL dendritic spine membrane ISO RGD:731547 1624291 (PMID:20434989) RGD PMID:20434989 dendritic spine membrane IEA UniProtKB:P42261 , ensembl:ENSP000004289941600115 GO_REF:0000107 Ensembl GO_REF:0000107 early endosome IDA 8554168 PMID:11100149 UniProt early endosome membrane IDA 13432260 PMID:15456832 UniProt endoplasmic reticulum ISO RGD:735685 1624291 (MGI:MGI:3654399, PMID:16814779) RGD MGI:MGI:3654399 , PMID:16814779 endoplasmic reticulum IEA UniProtKB:P23818 , ensembl:ENSMUSP000000444941600115 GO_REF:0000107 Ensembl GO_REF:0000107 endoplasmic reticulum membrane IDA 13432260 PMID:15456832 UniProt excitatory synapse IDA 8554379 PMID:19730411 BHF-UCL excitatory synapse IEA UniProtKB:P23818 , ensembl:ENSMUSP000000444941600115 GO_REF:0000107 Ensembl GO_REF:0000107 glutamatergic synapse IDA 13702224 PMID:15610164 SynGO glutamatergic synapse ISO RGD:735685 1624291 (MGI:MGI:2178282 more ... RGD MGI:MGI:2178282 more ... glutamatergic synapse IEA UniProtKB:P23818 , ensembl:ENSMUSP000000444941600115 GO_REF:0000107 Ensembl GO_REF:0000107 integral component of membrane IEA UniProtKB-KW:KW-0812 1600115 GO_REF:0000043 UniProt GO_REF:0000043 integral component of postsynaptic density membrane IDA 13702224 PMID:15610164 SynGO integral component of postsynaptic density membrane ISO RGD:735685 1624291 (MGI:MGI:3615715, PMID:14555717) RGD MGI:MGI:3615715 , PMID:14555717 integral component of postsynaptic density membrane IEA UniProtKB:P23818 , ensembl:ENSMUSP000000444941600115 GO_REF:0000107 Ensembl GO_REF:0000107 integral component of postsynaptic membrane IDA 2316535 PMID:16903873 SynGO integral component of presynaptic membrane IDA 2316535 PMID:16903873 SynGO ionotropic glutamate receptor complex ISO RGD:735685 1624291 (MGI:MGI:3852309, PMID:15207857) RGD MGI:MGI:3852309 , PMID:15207857 ionotropic glutamate receptor complex TAS 8554410 PMID:11836517 UniProt membrane ISO RGD:735685 1624291 (MGI:MGI:3690398, PMID:17093100) RGD MGI:MGI:3690398 , PMID:17093100 neuromuscular junction IDA 4107718 RGD neuron projection IDA 2312658 RGD neuron projection ISO RGD:735685 1624291 (MGI:MGI:5013997, PMID:21558424) RGD MGI:MGI:5013997 , PMID:21558424 neuron spine IDA 4107359 RGD neuron spine ISO RGD:735685 1624291 (MGI:MGI:3624607, PMID:16606358) RGD MGI:MGI:3624607 , PMID:16606358 neuronal cell body IDA 1600985 RGD neuronal cell body ISO RGD:735685 1624291 (MGI:MGI:3624607, PMID:16606358) RGD MGI:MGI:3624607 , PMID:16606358 neuronal cell body IEA UniProtKB:P23818 , ensembl:ENSMUSP000000444941600115 GO_REF:0000107 Ensembl GO_REF:0000107 neuronal cell body IDA 12907563 PMID:20032460 ARUK-UCL neuronal cell body IDA 8554168 PMID:11100149 UniProt neuronal cell body ISO RGD:8880027 1624291 RGD RGD:11556236 perisynaptic space ISO RGD:735685 1624291 (MGI:MGI:6150569, PMID:29490264) RGD MGI:MGI:6150569 , PMID:29490264 plasma membrane IDA 13508620 ; 4107350 RGD plasma membrane TAS 1600115 Reactome:R-RNO-9620437 Reactome Reactome:R-RNO-9620437 plasma membrane IBA FB:FBgn0004620 more ... 13792537 PMID:21873635 GO_Central plasma membrane IDA 25671385 PMID:27881773 ARUK-UCL plasma membrane ISO RGD:735685 1624291 (MGI:MGI:3624607, PMID:16606358) RGD MGI:MGI:3624607 , PMID:16606358 postsynapse ISO RGD:735685 1624291 (MGI:MGI:5816444, PMID:21144999) RGD MGI:MGI:5816444 , PMID:21144999 postsynaptic density IDA 1600985 RGD postsynaptic density ISO RGD:735685 1624291 (MGI:MGI:2653003 more ... RGD MGI:MGI:2653003 more ... postsynaptic density membrane ISO RGD:735685 1624291 (MGI:MGI:3615715 more ... RGD MGI:MGI:3615715 more ... postsynaptic membrane ISO RGD:735685 1624291 (MGI:MGI:3852309, PMID:15207857) RGD MGI:MGI:3852309 , PMID:15207857 postsynaptic membrane IEA UniProtKB-SubCell:SL-0219 1600115 GO_REF:0000044 UniProt GO_REF:0000044 protein-containing complex IDA 1641844 RGD recycling endosome ISO RGD:731547 1624291 (PMID:20434989) RGD PMID:20434989 recycling endosome IEA UniProtKB:P42261 , ensembl:ENSP000004289941600115 GO_REF:0000107 Ensembl GO_REF:0000107 recycling endosome membrane IDA 13432260 PMID:15456832 UniProt somatodendritic compartment ISO RGD:735685 1624291 (MGI:MGI:3794899, PMID:18341993) RGD MGI:MGI:3794899 , PMID:18341993 synapse ISO RGD:735685 1624291 (MGI:MGI:5529732, PMID:24259587) RGD MGI:MGI:5529732 , PMID:24259587 synapse IDA 2313285 PMID:10939335 SynGO-UCL synapse IDA 8553420 PMID:15681343 MGI synapse IMP 8553676 PMID:12536214 UniProt synaptic membrane IMP 13441201 PMID:27307232 UniProt synaptic membrane ISO RGD:735685 1624291 (MGI:MGI:5514106, PMID:23676497) RGD MGI:MGI:5514106 , PMID:23676497 synaptic membrane IDA 1580308 PMID:11910117 ARUK-UCL synaptic vesicle ISO RGD:735685 1624291 (MGI:MGI:4454727, PMID:20418887) RGD MGI:MGI:4454727 , PMID:20418887 synaptic vesicle IEA UniProtKB:P23818 , ensembl:ENSMUSP000000444941600115 GO_REF:0000107 Ensembl GO_REF:0000107 synaptic vesicle membrane ISO RGD:735685 1624291 (MGI:MGI:6150569, PMID:29490264) RGD MGI:MGI:6150569 , PMID:29490264 Molecular Function adenylate cyclase binding IDA 4107483 RGD AMPA glutamate receptor activity IDA 8554136 PMID:19265014 UniProt AMPA glutamate receptor activity IBA PANTHER:PTN000438081 more ... 13792537 PMID:21873635 GO_Central AMPA glutamate receptor activity ISO RGD:735685 1624291 (MGI:MGI:6150569, PMID:29490264) RGD MGI:MGI:6150569 , PMID:29490264 AMPA glutamate receptor activity IEA UniProtKB:P42261 , ensembl:ENSP000004289941600115 GO_REF:0000107 Ensembl GO_REF:0000107 AMPA glutamate receptor activity ISO RGD:731547 1624291 (PMID:20805473), (PMID:21172611) RGD PMID:20805473 , PMID:21172611 amyloid-beta binding IPI ComplexPortal:CPX-1134 12907563 PMID:20032460 ARUK-UCL beta-2 adrenergic receptor binding IPI RGD:2060 4107483 RGD beta-2 adrenergic receptor binding IPI UniProtKB:P10608 12907549 PMID:20395454 ARUK-UCL G-protein alpha-subunit binding IPI RGD:2716 4107483 RGD G-protein beta-subunit binding IDA 4107483 Gbeta1-4 RGD glutamate receptor binding IPI UniProtKB:P19491 15023489 PMID:21639859 UniProt identical protein binding IPI UniProtKB:P19490 8554491 PMID:19461580 IntAct identical protein binding IPI UniProtKB:P19490 15023489 PMID:21639859 UniProt identical protein binding IPI UniProtKB:P19490 8553419 PMID:21317873 IntAct immunoglobulin binding IPI UniProtKB:Q5DX21 11085699 PMID:26595655 UniProt immunoglobulin binding IPI UniProtKB:Q5U2P2 11085699 PMID:26595655 UniProt ionotropic glutamate receptor activity IDA 4107730 RGD ionotropic glutamate receptor activity IEA InterPro:IPR019594 1600115 GO_REF:0000002 InterPro GO_REF:0000002 ligand-gated ion channel activity IBA FB:FBgn0004619 more ... 13792537 PMID:21873635 GO_Central myosin V binding IPI RGD:621347 2312658 RGD neurotransmitter receptor activity involved in regulation of postsynaptic cytosolic calcium ion concentration ISO RGD:735685 1624291 (MGI:MGI:5819333, PMID:24983627) RGD MGI:MGI:5819333 , PMID:24983627 neurotransmitter receptor activity involved in regulation of postsynaptic cytosolic calcium ion concentration IBA MGI:MGI:95808 , PANTHER:PTN002708849 13792537 PMID:21873635 GO_Central neurotransmitter receptor activity involved in regulation of postsynaptic cytosolic calcium ion concentration IEA UniProtKB:P23818 , ensembl:ENSMUSP000000444941600115 GO_REF:0000107 Ensembl GO_REF:0000107 PDZ domain binding IPI RGD:2505 2306831 RGD protein binding IPI RGD:1563435 4107729 RGD protein binding IPI UniProtKB:Q5U2P2 13825438 PMID:16108831 UniProt protein binding IPI UniProtKB:P11275 13432269 PMID:21135237 IntAct protein binding IPI UniProtKB:B2GV74 13432347 PMID:20534517 IntAct protein binding IPI UniProtKB:Q71RJ2 13432333 PMID:19805317 IntAct protein binding IPI UniProtKB:Q71RJ2 13432301 PMID:19208802 IntAct protein binding IPI UniProtKB:Q5FVC2 13432301 PMID:19208802 IntAct protein binding IPI UniProtKB:P36202 13432260 PMID:15456832 UniProt protein binding IPI UniProtKB:Q71RJ2 8553314 PMID:24418105 IntAct protein binding IPI UniProtKB:Q71RJ2 10412303 PMID:21376300 IntAct protein binding IPI UniProtKB:P19491 8553419 PMID:21317873 IntAct protein binding IPI UniProtKB:P19491 4107483 PMID:19942860 IntAct protein binding IPI UniProtKB:P10608 4107483 PMID:19942860 IntAct protein binding IPI UniProtKB:P70569 2312658 PMID:16338934 IntAct protein binding IPI UniProtKB:P19491 2312658 PMID:16338934 IntAct protein binding ISO RGD:735685 1624291 PR:Q60612 more ... RGD MGI:MGI:2667266 more ... protein binding IPI UniProtKB:Q71RJ2 8553646 PMID:20805473 UniProt protein binding IPI UniProtKB:Q5BJU5 8553646 PMID:20805473 UniProt protein binding IPI UniProtKB:Q8VHW8 8554069 PMID:19234459 UniProt protein binding IPI UniProtKB:Q8VHW8 8554789 PMID:18817736 UniProt protein binding IPI UniProtKB:P19491 8553683 PMID:11348590 UniProt protein binding ISO RGD:731547 1624291 UniProtKB:Q6PI25 , UniProtKB:Q9Y698 (PMID:20805473) RGD PMID:20805473 protein binding IPI RGD:2505 4107524 RGD protein binding IPI RGD:71095 4107483 RGD protein binding IPI RGD:628808 8553314 RGD protein binding IPI RGD:628705 13508620 RGD protein binding IPI RGD:1311592 4107718 RGD protein C-terminus binding IPI UniProtKB:P10608 12907549 PMID:20395454 ARUK-UCL protein domain specific binding IPI RGD:2505 , RGD:71095 2304049 RGD protein kinase A binding IDA 4107483 RIIalpha subunit RGD protein kinase binding IPI RGD:70982 1641844 RGD scaffold protein binding IPI UniProtKB:P24587 2313285 PMID:10939335 SynGO-UCL signaling receptor activity IBA FB:FBgn0004619 more ... 13792537 PMID:21873635 GO_Central small GTPase binding IPI RGD:3529 2304049 RGD transmitter-gated ion channel activity involved in regulation of postsynaptic membrane potential ISO RGD:735685 1624291 (MGI:MGI:2178282, PMID:11431570) RGD MGI:MGI:2178282 , PMID:11431570 transmitter-gated ion channel activity involved in regulation of postsynaptic membrane potential IEA UniProtKB:P23818 , ensembl:ENSMUSP000000444941600115 GO_REF:0000107 Ensembl GO_REF:0000107
Gene-Chemical Interaction Annotations
