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Gene: Gria1 (glutamate ionotropic receptor AMPA type subunit 1) Rattus norvegicus
Symbol: Gria1
Name: glutamate ionotropic receptor AMPA type subunit 1
Description: Exhibits several functions, including AMPA glutamate receptor activity; G-protein alpha-subunit binding activity; and enzyme binding activity. Involved in several processes, including cellular response to organonitrogen compound; long-term memory; and modulation of chemical synaptic transmission. Localizes to several cellular components, including the cytoplasm; dendrite; and integral component of plasma membrane. Used to study hyperhomocysteinemia. Biomarker of epilepsy; hepatic encephalopathy; status epilepticus; and visual epilepsy. Orthologous to human GRIA1 (glutamate ionotropic receptor AMPA type subunit 1); PARTICIPATES IN calcium/calmodulin dependent kinase 2 signaling pathway; ephrin - ephrin receptor bidirectional signaling axis; amyotrophic lateral sclerosis pathway; INTERACTS WITH (+)-pilocarpine; (S)-AMPA; 1-(4-methoxybenzyl)-3-(5-nitro-1,3-thiazol-2-yl)urea.
Type: protein-coding
Also known as: AMPA-selective glutamate receptor 1; GluA1; gluR-1; gluR-A; gluR-K1; GluR1; glutamate receptor 1; glutamate receptor A; glutamate receptor subunit GluR1; glutamate receptor, ionotropic, AMPA 1; glutamate receptor, ionotropic, AMPA1 (alpha 1)
Latest Assembly: Rnor_6.0 - RGSC Genome Assembly v6.0
NCBI Annotation Information: Annotation category: partial on reference assembly
Rat AssemblyChrPosition (strand)SourceGenome Browsers
Rnor_6.01042,441,723 - 42,760,200 (+)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_5.01042,257,736 - 42,571,220 (+)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.41042,613,359 - 42,616,610 (+)NCBIRGSC3.4rn4RGSC3.4
Celera1040,506,762 - 40,822,664 (+)NCBICelera
Cytogenetic Map10q22NCBI
JBrowse: View Region in Genome Browser (JBrowse)

Disease Annotations
Gene-Chemical Interaction Annotations
Gene Ontology Annotations
Molecular Pathway Annotations
References - curated
References - uncurated
RGD Disease Portals


Comparative Map Data
Position Markers
QTLs in Region (Rnor_6.0)
miRNA Target Status


Nucleotide Sequences
Protein Sequences

Strain Variation

Strain Sequence Variants (Rnor 5.0)

Additional Information

External Database Links
Nomenclature History
More on Gria1
Alliance Gene
Ensembl Gene
JBrowse: rn5 rn6
NCBI Genome Data Viewer

RGD Object Information
RGD ID: 621531
Created: 2002-08-06
Species: Rattus norvegicus
Last Modified: 2019-05-21
Status: ACTIVE


RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.