Gene: Gria1 (glutamate ionotropic receptor AMPA type subunit 1) Rattus norvegicus
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Symbol: Gria1
Name: glutamate ionotropic receptor AMPA type subunit 1
Description: ENCODES a protein that exhibits adenylate cyclase binding; AMPA glutamate receptor activity; amyloid-beta binding; INVOLVED IN cellular response to amine stimulus; cellular response to amino acid stimulus; cellular response to dsRNA; PARTICIPATES IN calcium/calmodulin dependent kinase 2 signaling pathway; ephrin - ephrin receptor bidirectional signaling axis; amyotrophic lateral sclerosis pathway; ASSOCIATED WITH Central Nervous System Viral Diseases; epilepsy; Fetal Growth Retardation; FOUND IN AMPA glutamate receptor complex; asymmetric synapse; cell surface; INTERACTS WITH (+)-pilocarpine; (S)-AMPA; 1-(4-methoxybenzyl)-3-(5-nitro-1,3-thiazol-2-yl)urea
AGR Description: Exhibits several functions, including AMPA glutamate receptor activity, G-protein alpha-subunit binding activity, and enzyme binding activity; involved in several processes, including cellular response to dsRNA, cellular response to organonitrogen compound, and modulation of chemical synaptic transmission; localizes to several cellular components, including the cytoplasm, intrinsic component of plasma membrane, and neuron projection; used to study hyperhomocysteinemia; biomarker of epilepsy, hepatic encephalopathy, status epilepticus, and visual epilepsy; orthologous to human GRIA1 (glutamate ionotropic receptor AMPA type subunit 1).
Merged Description: Exhibits several functions, including AMPA glutamate receptor activity, G-protein alpha-subunit binding activity, and enzyme binding activity; involved in several processes, including cellular response to dsRNA, cellular response to organonitrogen compound, and modulation of chemical synaptic transmission; localizes to several cellular components, including the cytoplasm, intrinsic component of plasma membrane, and neuron projection; used to study hyperhomocysteinemia; biomarker of epilepsy, hepatic encephalopathy, status epilepticus, and visual epilepsy; orthologous to human GRIA1 (glutamate ionotropic receptor AMPA type subunit 1); PARTICIPATES IN calcium/calmodulin dependent kinase 2 signaling pathway; ephrin - ephrin receptor bidirectional signaling axis; amyotrophic lateral sclerosis pathway; INTERACTS WITH (+)-pilocarpine; (S)-AMPA; 1-(4-methoxybenzyl)-3-(5-nitro-1,3-thiazol-2-yl)urea.
Type: protein-coding
RefSeq Status: PROVISIONAL
Also known as: AMPA-selective glutamate receptor 1; GluA1; gluR-1; gluR-A; gluR-K1; GluR1; glutamate receptor 1; glutamate receptor A; glutamate receptor subunit GluR1; glutamate receptor, ionotropic, AMPA 1; glutamate receptor, ionotropic, AMPA1 (alpha 1)
Orthologs:
Latest Assembly: Rnor_6.0 - RGSC Genome Assembly v6.0
NCBI Annotation Information: Annotation category: partial on reference assembly
Position:
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Rnor_6.01042,441,723 - 42,760,200 (+)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_5.01042,257,736 - 42,571,220 (+)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.41042,613,359 - 42,616,610 (+)NCBIRGSC3.4rn4RGSC3.4
Celera1040,506,762 - 40,822,664 (+)NCBICelera
Cytogenetic Map10q22NCBI
JBrowse: View Region in Genome Browser (JBrowse)
Model


Disease Annotations
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References - uncurated
RGD Disease Portals

Genomics

Comparative Map Data
Position Markers
QTLs in Region (Rnor_6.0)
miRNA Target Status

Sequence

Nucleotide Sequences
Protein Sequences
Transcriptome

Strain Variation

Strain Sequence Variants (Rnor 5.0)

Additional Information

External Database Links
Nomenclature History
 
More on Gria1
Alliance Gene
NCBI Gene
Ensembl Gene
JBrowse: rn5 rn6
NCBI Genome Data Viewer

RGD Object Information
RGD ID: 621531
Created: 2002-08-06
Species: Rattus norvegicus
Last Modified: 2019-04-12
Status: ACTIVE



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RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.