Ccng1 (cyclin G1) - Rat Genome Database

Send us a Message



Submit Data |  Help |  Video Tutorials |  News |  Publications |  Download |  REST API |  Citing RGD |  Contact   
Gene: Ccng1 (cyclin G1) Rattus norvegicus
Analyze
Symbol: Ccng1
Name: cyclin G1
RGD ID: 2295
Description: Predicted to enable cyclin-dependent protein serine/threonine kinase regulator activity. Involved in several processes, including mitotic G2 DNA damage checkpoint signaling; response to gravity; and syncytium formation. Located in dendrite; neuronal cell body; and perinuclear region of cytoplasm. Used to study hepatocellular carcinoma. Biomarker of breast cancer; hepatocellular carcinoma; muscular atrophy; and traumatic brain injury. Human ortholog(s) of this gene implicated in endocrine gland cancer (multiple); localized osteosarcoma; ovarian cancer (multiple); and sarcoma. Orthologous to human CCNG1 (cyclin G1); PARTICIPATES IN p53 signaling pathway; INTERACTS WITH (+)-schisandrin B; 1,2-dimethylhydrazine; 1-naphthyl isothiocyanate.
Type: protein-coding
RefSeq Status: VALIDATED
Previously known as: Ccng; CYCG; cyclin-G; cyclin-G1; MGC93642
RGD Orthologs
Human
Mouse
Chinchilla
Bonobo
Dog
Squirrel
Pig
Green Monkey
Naked Mole-Rat
Alliance Orthologs
More Info more info ...
Latest Assembly: GRCr8 - GRCr8 Assembly
Position:
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr81025,678,503 - 25,684,876 (-)NCBIGRCr8
mRatBN7.21025,176,231 - 25,182,604 (-)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl1025,176,234 - 25,181,641 (-)EnsemblmRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx1029,938,596 - 29,945,089 (-)NCBIRnor_SHRUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.01029,427,123 - 29,433,616 (-)NCBIRnor_SHRSPUTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.01024,913,784 - 24,920,277 (-)NCBIRnor_WKYUTH_Rnor_WKY_Bbb_1.0
Rnor_6.01025,903,925 - 25,910,298 (-)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl1025,903,911 - 25,910,325 (-)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.01025,754,109 - 25,760,482 (-)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.41025,776,380 - 25,782,754 (-)NCBIRGSC3.4RGSC_v3.4rn4RGSC3.4
RGSC_v3.11025,777,429 - 25,783,775 (-)NCBI
Celera1024,735,527 - 24,741,900 (-)NCBICelera
RH 3.4 Map10255.21RGD
Cytogenetic Map10q12NCBI
JBrowse: View Region in Genome Browser (JBrowse)
Model


1 to 20 of 36 rows

  
Object Symbol
Species
Term
Qualifier
Evidence
With
Reference
Notes
Source
Original Reference(s)
Ccng1RatAlzheimer's disease  ISOCCNG1 (Homo sapiens)2316025protein:increased expression:brain and neuronRGD 
Ccng1Ratbreast adenocarcinoma  ISOCcng1 (Mus musculus)2315939mRNA and protein:altered expression:mammary (mouse)RGD 
Ccng1Ratbreast cancer treatmentIEP 151356928 RGD 
Ccng1Ratcervix uteri carcinoma in situ  ISOCCNG1 (Homo sapiens)2316022protein:increased expression:uterine cervixRGD 
Ccng1RatExperimental Liver Neoplasms  ISOCcng1 (Mus musculus)151361200 RGD 
Ccng1Rathead and neck cancer  ISOCCNG1 (Homo sapiens)151361200mRNA:decreased expression:head and neck (human)RGD 
Ccng1Rathepatocellular carcinoma  IGINotch3 (Rattus norvegicus)151356922 RGD 
Ccng1Rathepatocellular carcinoma severityISOCCNG1 (Homo sapiens)151361198protein:decreased expression:liver (human)RGD 
Ccng1Rathepatocellular carcinoma  ISOCcng1 (Mus musculus)151361200 RGD 
Ccng1Rathepatocellular carcinoma treatmentISOCCNG1 (Homo sapiens)151356970human cells in mouse modelRGD 
Ccng1Rathepatocellular carcinoma severityISOCCNG1 (Homo sapiens)151356981protein:increased expression:liver (human)RGD 
Ccng1Rathepatocellular carcinoma disease_progressionISOCCNG1 (Homo sapiens)151356967protein:increased expression:liver (human)RGD 
Ccng1Rathepatocellular carcinoma  ISOCCNG1 (Homo sapiens)151356967human cells in mouse modelRGD 
Ccng1Rathepatocellular carcinoma treatmentIEP 151356932 RGD 
Ccng1Rathepatocellular carcinoma treatmentIEP 151356933 RGD 
Ccng1Ratleiomyoma  ISOCCNG1 (Homo sapiens)2316023mRNA more ...RGD 
Ccng1RatLiver Metastasis treatmentISOCCNG1 (Homo sapiens)151356987human cells in mouse modelRGD 
Ccng1Ratlocalized osteosarcoma treatmentISOCCNG1 (Homo sapiens)151356969human cells in mouse modelRGD 
Ccng1Ratlung cancer treatmentISOCCNG1 (Homo sapiens)151361106human cells in mouse modelRGD 
Ccng1Ratlung metastasis  ISOCcng1 (Mus musculus)151361205 RGD 
1 to 20 of 36 rows
Object Symbol
Species
Term
Qualifier
Evidence
With
Reference
Notes
Source
Original Reference(s)
Ccng1Rathereditary breast ovarian cancer syndrome  ISOCCNG1 (Homo sapiens)8554872ClinVar Annotator: match by term: Hereditary breast ovarian cancer syndromeClinVarPMID:25741868
Object Symbol
Species
Term
Qualifier
Evidence
With
Reference
Notes
Source
Original Reference(s)
Ccng1RatExperimental Liver Cirrhosis  ISOCCNG1 (Homo sapiens)11554173CTD Direct Evidence: marker/mechanismCTDPMID:25380136
Ccng1RatLung Neoplasms  ISOCCNG1 (Homo sapiens)11554173CTD Direct Evidence: marker/mechanismCTDPMID:16289808

1 to 20 of 294 rows

  
Object Symbol
Species
Term
Qualifier
Evidence
With
Reference
Notes
Source
Original Reference(s)
Ccng1Rat(+)-schisandrin B multiple interactionsEXP 6480464schizandrin B inhibits the reaction [Carbon Tetrachloride results in increased expression of CCNG1 mRNA]CTDPMID:31150632
Ccng1Rat(+/-)-Aegeline multiple interactionsISOCcng1 (Mus musculus)6480464[Caffeine co-treated with coclaurine co-treated with aegeline co-treated with higenamine co-treated with Yohimbine co-treated with Hydrolyzable Tannins] results in increased expression of CCNG1 mRNACTDPMID:28843594
Ccng1Rat(-)-citrinin multiple interactionsISOCCNG1 (Homo sapiens)6480464[Citrinin co-treated with ochratoxin A] results in decreased expression of CCNG1 mRNA and [Citrinin co-treated with ochratoxin A] results in decreased expression of CCNG1 proteinCTDPMID:30428381
Ccng1Rat(-)-epigallocatechin 3-gallate increases expressionISOCCNG1 (Homo sapiens)6480464epigallocatechin gallate results in increased expression of CCNG1 mRNA and epigallocatechin gallate results in increased expression of CCNG1 proteinCTDPMID:18851785
Ccng1Rat(1->4)-beta-D-glucan multiple interactionsISOCcng1 (Mus musculus)6480464[perfluorooctane sulfonic acid co-treated with Cellulose] results in increased expression of CCNG1 mRNACTDPMID:36331819
Ccng1Rat(RS)-coclaurine multiple interactionsISOCcng1 (Mus musculus)6480464[Caffeine co-treated with coclaurine co-treated with aegeline co-treated with higenamine co-treated with Yohimbine co-treated with Hydrolyzable Tannins] results in increased expression of CCNG1 mRNACTDPMID:28843594
Ccng1Rat(RS)-norcoclaurine multiple interactionsISOCcng1 (Mus musculus)6480464[Caffeine co-treated with coclaurine co-treated with aegeline co-treated with higenamine co-treated with Yohimbine co-treated with Hydrolyzable Tannins] results in increased expression of CCNG1 mRNACTDPMID:28843594
Ccng1Rat(S)-coclaurine multiple interactionsISOCcng1 (Mus musculus)6480464[Caffeine co-treated with coclaurine co-treated with aegeline co-treated with higenamine co-treated with Yohimbine co-treated with Hydrolyzable Tannins] results in increased expression of CCNG1 mRNACTDPMID:28843594
Ccng1Rat(S)-naringenin multiple interactionsISOCCNG1 (Homo sapiens)6480464[naringenin co-treated with bisphenol A] results in decreased expression of CCNG1 mRNACTDPMID:36235125
Ccng1Rat1,2-dimethylhydrazine increases expressionEXP 64804641 and 2-Dimethylhydrazine results in increased expression of CCNG1 mRNACTDPMID:27840820
Ccng1Rat1,2-dimethylhydrazine multiple interactionsISOCcng1 (Mus musculus)6480464[1 and 2-Dimethylhydrazine co-treated with Folic Acid] results in decreased expression of CCNG1 mRNACTDPMID:22206623
Ccng1Rat1,2-dimethylhydrazine decreases expressionISOCcng1 (Mus musculus)64804641 and 2-Dimethylhydrazine results in decreased expression of CCNG1 mRNACTDPMID:22206623
Ccng1Rat1,4-dioxane increases expressionISOCcng1 (Mus musculus)64804641 and 4-dioxane results in increased expression of CCNG1 mRNACTDPMID:33693819
Ccng1Rat1-naphthyl isothiocyanate increases expressionEXP 64804641-Naphthylisothiocyanate results in increased expression of CCNG1 mRNACTDPMID:17522070 more ...
Ccng1Rat1-nitropropane increases expressionEXP 64804641-nitropropane results in increased expression of CCNG1 mRNACTDPMID:17070881
Ccng1Rat17alpha-ethynylestradiol affects expressionISOCcng1 (Mus musculus)6480464Ethinyl Estradiol affects the expression of CCNG1 mRNACTDPMID:17555576
Ccng1Rat17alpha-ethynylestradiol increases expressionISOCcng1 (Mus musculus)6480464Ethinyl Estradiol results in increased expression of CCNG1 mRNACTDPMID:17942748
Ccng1Rat17alpha-ethynylestradiol multiple interactionsISOCcng1 (Mus musculus)6480464[Tetrachlorodibenzodioxin co-treated with Ethinyl Estradiol] results in increased expression of CCNG1 mRNACTDPMID:17942748
Ccng1Rat17beta-estradiol decreases expressionISOCCNG1 (Homo sapiens)6480464Estradiol results in decreased expression of CCNG1 mRNACTDPMID:16029874 and PMID:31614463
Ccng1Rat17beta-estradiol multiple interactionsEXP 6480464[Estradiol co-treated with Testosterone] results in increased expression of CCNG1 mRNACTDPMID:11375906

1 to 20 of 294 rows

Biological Process

  
Object Symbol
Species
Term
Qualifier
Evidence
With
Reference
Notes
Source
Original Reference(s)
Ccng1Ratcell division involved_inIEAUniProtKB-KW:KW-01321600115GO_REF:0000043UniProtGO_REF:0000043
Ccng1RatG1/S transition of mitotic cell cycle involved_inIBACGD:CAL0000185532 more ...1600115GO_REF:0000033GO_CentralGO_REF:0000033
Ccng1Ratmitotic G2 DNA damage checkpoint signaling  IMP 2316029 RGD 
Ccng1Ratnegative regulation of apoptotic process  IMP 2316030 RGD 
Ccng1Ratresponse to gravity  IEP 151361116 RGD 
Ccng1Ratsyncytium formation  IMP 2316030 RGD 

Cellular Component

  
Object Symbol
Species
Term
Qualifier
Evidence
With
Reference
Notes
Source
Original Reference(s)
Ccng1Ratcyclin-dependent protein kinase holoenzyme complex part_ofIBAMGI:108042 more ...1600115GO_REF:0000033GO_CentralGO_REF:0000033
Ccng1Ratcytoplasm is_active_inIBAFB:FBgn0000404 more ...1600115GO_REF:0000033GO_CentralGO_REF:0000033
Ccng1Ratdendrite  IDA 2316028 RGD 
Ccng1Ratneuronal cell body  IDA 2316028 RGD 
Ccng1Ratnucleus is_active_inIBAFB:FBgn0000404 more ...1600115GO_REF:0000033GO_CentralGO_REF:0000033
Ccng1Ratnucleus located_inIEAUniProtKB-SubCell:SL-01911600115GO_REF:0000044UniProtGO_REF:0000044
Ccng1Ratnucleus located_inIEAUniProtKB-KW:KW-05391600115GO_REF:0000043UniProtGO_REF:0000043
Ccng1Ratperinuclear region of cytoplasm  IDA 2316026 RGD 

Molecular Function

  
Object Symbol
Species
Term
Qualifier
Evidence
With
Reference
Notes
Source
Original Reference(s)
Ccng1Ratcyclin-dependent protein serine/threonine kinase regulator activity enablesIBACGD:CAL0000175354 more ...1600115GO_REF:0000033GO_CentralGO_REF:0000033
Ccng1Ratprotein binding enablesISOCCNG1 (Homo sapiens)1624291UniProtKB:O95995 more ...RGDPMID:17245430 more ...

Imported Annotations - KEGG (archival)

Object Symbol
Species
Term
Qualifier
Evidence
With
Reference
Notes
Source
Original Reference(s)
Ccng1Ratp53 signaling pathway   IEA 6907045 KEGGrno:04115

Imported Annotations - PID (archival)

Object Symbol
Species
Term
Qualifier
Evidence
With
Reference
Notes
Source
Original Reference(s)
Ccng1Ratp53 signaling pathway   ISOCCNG1 (Homo sapiens)6484113 PIDPID:200206

1 to 20 of 46 rows
#
Reference Title
Reference Citation
1. Increased expression of cyclin G1 in leiomyoma compared with normal myometrium. Baek WK, etal., Am J Obstet Gynecol. 2003 Mar;188(3):634-9.
2. Phase I/II and phase II studies of targeted gene delivery in vivo: intravenous Rexin-G for chemotherapy-resistant sarcoma and osteosarcoma. Chawla SP, etal., Mol Ther. 2009 Sep;17(9):1651-7. doi: 10.1038/mt.2009.126. Epub 2009 Jun 16.
3. Retroviral vector-mediated transfer of an antisense cyclin G1 construct inhibits osteosarcoma tumor growth in nude mice. Chen DS, etal., Hum Gene Ther. 1997 Sep 20;8(14):1667-74. doi: 10.1089/hum.1997.8.14-1667.
4. The relationship between Cyclin G1 and survival in patients treated surgically for HCC. Cui X, etal., Hepatogastroenterology. 2013 Jan-Feb;60(121):153-9. doi: 10.5754/hge12549.
5. Differential gene expression in mouse mammary adenocarcinomas in the presence and absence of wild type p53. Cui XS and Donehower LA, Oncogene. 2000 Dec 7;19(52):5988-96.
6. Structure and chromosomal assignment of the human cyclin G gene. Endo Y, etal., Genomics 1996 Nov 15;38(1):92-5.
7. MiR-122/cyclin G1 interaction modulates p53 activity and affects doxorubicin sensitivity of human hepatocarcinoma cells. Fornari F, etal., Cancer Res. 2009 Jul 15;69(14):5761-7. doi: 10.1158/0008-5472.CAN-08-4797. Epub 2009 Jul 7.
8. Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium. Gaudet P, etal., Brief Bioinform. 2011 Sep;12(5):449-62. doi: 10.1093/bib/bbr042. Epub 2011 Aug 27.
9. Suppression of p53 by Notch3 is mediated by Cyclin G1 and sustained by MDM2 and miR-221 axis in hepatocellular carcinoma. Giovannini C, etal., Oncotarget. 2014 Nov 15;5(21):10607-20. doi: 10.18632/oncotarget.2523.
10. Rat ISS GO annotations from GOA human gene data--August 2006 GOA data from the GO Consortium
11. Inhibition of metastatic tumor growth in nude mice by portal vein infusions of matrix-targeted retroviral vectors bearing a cytocidal cyclin G1 construct. Gordon EM, etal., Cancer Res. 2000 Jul 1;60(13):3343-7.
12. Systemic administration of a matrix-targeted retroviral vector is efficacious for cancer gene therapy in mice. Gordon EM, etal., Hum Gene Ther. 2001 Jan 20;12(2):193-204. doi: 10.1089/104303401750061258.
13. MicroRNA-488 inhibits ovarian cancer cell metastasis through regulating CCNG1 and p53 expression. Guo JY, etal., Eur Rev Med Pharmacol Sci. 2020 Mar;24(6):2902-2910. doi: 10.26355/eurrev_202003_20654.
14. Current concepts in pathophysiology and management of hepatocellular carcinoma. Hamza AH, etal., Acta Biochim Pol. 2015;62(3):573-80. doi: 10.18388/abp.2015_1030. Epub 2015 Sep 8.
15. Roscovitine reduces neuronal loss, glial activation, and neurologic deficits after brain trauma. Hilton GD, etal., J Cereb Blood Flow Metab. 2008 Nov;28(11):1845-59. doi: 10.1038/jcbfm.2008.75. Epub 2008 Jul 9.
16. Changes in expression of cell cycle regulators after G1 progression upon repetitive thioacetamide treatment in rat liver. Hong SH, etal., Exp Mol Med. 2002 Nov 30;34(5):361-6.
17. Alcohol facilitates HCV RNA replication via up-regulation of miR-122 expression and inhibition of cyclin G1 in human hepatoma cells. Hou W, etal., Alcohol Clin Exp Res. 2013 Apr;37(4):599-608. doi: 10.1111/acer.12005. Epub 2012 Nov 5.
18. The role of Cyclin G1 in cellular proliferation and apoptosis of human epithelial ovarian cancer. Jiang L, etal., J Mol Histol. 2015 Jun;46(3):291-302. doi: 10.1007/s10735-015-9622-7. Epub 2015 May 17.
19. Increased Cyclin G1 Immunoreactivity During Alzheimer's Disease. Jordan-Sciutto KL, etal., J Alzheimers Dis. 1999 Dec;1(6):409-417.
20. CR8, a novel inhibitor of CDK, limits microglial activation, astrocytosis, neuronal loss, and neurologic dysfunction after experimental traumatic brain injury. Kabadi SV, etal., J Cereb Blood Flow Metab. 2014 Mar;34(3):502-13. doi: 10.1038/jcbfm.2013.228. Epub 2014 Jan 8.
1 to 20 of 46 rows
PMID:7784084   PMID:11983168   PMID:15489334  



Ccng1
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr81025,678,503 - 25,684,876 (-)NCBIGRCr8
mRatBN7.21025,176,231 - 25,182,604 (-)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl1025,176,234 - 25,181,641 (-)EnsemblmRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx1029,938,596 - 29,945,089 (-)NCBIRnor_SHRUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.01029,427,123 - 29,433,616 (-)NCBIRnor_SHRSPUTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.01024,913,784 - 24,920,277 (-)NCBIRnor_WKYUTH_Rnor_WKY_Bbb_1.0
Rnor_6.01025,903,925 - 25,910,298 (-)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl1025,903,911 - 25,910,325 (-)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.01025,754,109 - 25,760,482 (-)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.41025,776,380 - 25,782,754 (-)NCBIRGSC3.4RGSC_v3.4rn4RGSC3.4
RGSC_v3.11025,777,429 - 25,783,775 (-)NCBI
Celera1024,735,527 - 24,741,900 (-)NCBICelera
RH 3.4 Map10255.21RGD
Cytogenetic Map10q12NCBI
CCNG1
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh385163,437,571 - 163,457,640 (+)NCBIGRCh38GRCh38hg38GRCh38
GRCh38.p14 Ensembl5163,437,569 - 163,448,199 (+)EnsemblGRCh38hg38GRCh38
GRCh375162,864,577 - 162,875,205 (+)NCBIGRCh37GRCh37hg19GRCh37
Build 365162,797,155 - 162,804,600 (+)NCBINCBI36Build 36hg18NCBI36
Build 345162,797,154 - 162,804,598NCBI
Celera5158,898,684 - 158,906,130 (+)NCBICelera
Cytogenetic Map5q34NCBI
HuRef5157,964,260 - 157,971,705 (+)NCBIHuRef
CHM1_15162,297,037 - 162,304,482 (+)NCBICHM1_1
T2T-CHM13v2.05163,972,739 - 163,983,375 (+)NCBIT2T-CHM13v2.0
Ccng1
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm391140,639,379 - 40,646,044 (-)NCBIGRCm39GRCm39mm39
GRCm39 Ensembl1140,639,379 - 40,646,138 (-)EnsemblGRCm39 Ensembl
GRCm381140,748,552 - 40,755,309 (-)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl1140,748,552 - 40,755,311 (-)EnsemblGRCm38mm10GRCm38
MGSCv371140,562,054 - 40,568,788 (-)NCBIGRCm37MGSCv37mm9NCBIm37
MGSCv361140,591,975 - 40,598,709 (-)NCBIMGSCv36mm8
Celera1144,600,600 - 44,607,334 (-)NCBICelera
Cytogenetic Map11A5NCBI
cM Map1124.42NCBI
Ccng1
(Chinchilla lanigera - long-tailed chinchilla)
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0NW_00495540816,846,050 - 16,850,365 (+)NCBIChiLan1.0ChiLan1.0
CCNG1
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
NHGRI_mPanPan1-v24158,610,583 - 158,624,484 (+)NCBINHGRI_mPanPan1-v2
NHGRI_mPanPan15156,750,429 - 156,757,885 (+)NCBINHGRI_mPanPan1
Mhudiblu_PPA_v05158,814,563 - 158,822,019 (+)NCBIMhudiblu_PPA_v0Mhudiblu_PPA_v0panPan3
PanPan1.15165,591,279 - 165,598,728 (+)NCBIpanpan1.1PanPan1.1panPan2
PanPan1.1 Ensembl5165,592,971 - 165,598,728 (+)Ensemblpanpan1.1panPan2
CCNG1
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.1447,800,697 - 47,808,259 (-)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
CanFam3.1 Ensembl447,801,575 - 47,808,211 (-)EnsemblCanFam3.1canFam3CanFam3.1
Dog10K_Boxer_Tasha447,693,783 - 47,701,354 (-)NCBIDog10K_Boxer_Tasha
ROS_Cfam_1.0448,231,625 - 48,239,215 (-)NCBIROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl448,231,625 - 48,238,937 (-)EnsemblROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.1448,014,780 - 48,022,368 (-)NCBIUMICH_Zoey_3.1
UNSW_CanFamBas_1.0448,173,025 - 48,180,607 (-)NCBIUNSW_CanFamBas_1.0
UU_Cfam_GSD_1.0448,692,928 - 48,700,530 (-)NCBIUU_Cfam_GSD_1.0
Ccng1
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HiC_Itri_2NW_024407213102,164,944 - 102,171,907 (-)NCBIHiC_Itri_2
SpeTri2.0 EnsemblNW_004936515614,290 - 619,963 (-)EnsemblSpeTri2.0SpeTri2.0 Ensembl
SpeTri2.0NW_004936515614,287 - 621,213 (-)NCBISpeTri2.0SpeTri2.0SpeTri2.0
CCNG1
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 Ensembl1660,349,258 - 60,356,738 (-)EnsemblSscrofa11.1susScr11Sscrofa11.1
Sscrofa11.11660,349,255 - 60,356,737 (-)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
Sscrofa10.21665,189,603 - 65,197,085 (-)NCBISscrofa10.2Sscrofa10.2susScr3
LOC103244924
(Chlorocebus sabaeus - green monkey)
Green Monkey AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.12365,709,759 - 65,716,913 (+)NCBIChlSab1.1ChlSab1.1chlSab2
ChlSab1.1 Ensembl2365,709,786 - 65,714,711 (+)EnsemblChlSab1.1ChlSab1.1 EnsemblchlSab2
Vero_WHO_p1.0NW_0236660971,066,729 - 1,073,889 (-)NCBIVero_WHO_p1.0Vero_WHO_p1.0
Ccng1
(Heterocephalus glaber - naked mole-rat)
Naked Mole-Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla_female_1.0 EnsemblNW_00462473326,367,200 - 26,376,664 (-)EnsemblHetGla_female_1.0HetGla_female_1.0 EnsemblhetGla2
HetGla 1.0NW_00462473326,366,448 - 26,378,062 (-)NCBIHetGla_female_1.0HetGla 1.0hetGla2

.

.
Variants in Ccng1
32 total Variants

Predicted Target Of
Summary Value
Count of predictions:833
Count of miRNA genes:329
Interacting mature miRNAs:420
Transcripts:ENSRNOT00000065633
Prediction methods:Microtar, Miranda, Targetscan
Result types:miRGate_prediction

The detailed report is available here: Full Report CSV TAB Printer

miRNA Target Status data imported from miRGate (http://mirgate.bioinfo.cnio.es/).
For more information about miRGate, see PMID:25858286 or access the full paper here.


1 to 10 of 38 rows
The following QTLs overlap with this region.    Full Report CSV TAB Printer Gviewer
RGD ID
Symbol
Name
LOD
P Value
Trait
Sub Trait
Chr
Start
Stop
Species
6893352Bw100Body weight QTL 1000.330.6body mass (VT:0001259)body weight (CMO:0000012)11590666560906665Rat
9589136Insul27Insulin level QTL 2710.460.001blood insulin amount (VT:0001560)plasma insulin level (CMO:0000342)101147401056474010Rat
631564Apr3Acute phase response QTL 33.9blood interleukin-6 amount (VT:0008595)plasma interleukin-6 level (CMO:0001927)101527595560275955Rat
724556Pur2Proteinuria QTL 25.5urine protein amount (VT:0005160)urine protein level (CMO:0000591)102242750090627625Rat
8662860Vetf10Vascular elastic tissue fragility QTL 10artery integrity trait (VT:0010639)number of ruptures of the internal elastic lamina of the abdominal aorta and iliac arteries (CMO:0002562)10615418273453136Rat
2313066Bss63Bone structure and strength QTL 631.40.0001tibia strength trait (VT:1000284)bone polar moment of inertia (CMO:0001558)10538701450387014Rat
631554Bp133Blood pressure QTL 1330.005arterial blood pressure trait (VT:2000000)systolic blood pressure (CMO:0000004)1074336463851208Rat
2313064Bmd71Bone mineral density QTL 710.90.0001tibia mineral mass (VT:1000283)compact volumetric bone mineral density (CMO:0001730)10538701450387014Rat
61325Aia5Adjuvant induced arthritis QTL 50.01joint integrity trait (VT:0010548)joint inflammation composite score (CMO:0000919)1023444813104060283Rat
70223Bp57Blood pressure QTL 575arterial blood pressure trait (VT:2000000)systolic blood pressure (CMO:0000004)10180676123Rat

1 to 10 of 38 rows
RH138781  
Rat AssemblyChrPosition (strand)SourceJBrowse
mRatBN7.21025,178,618 - 25,178,780 (+)MAPPERmRatBN7.2
Rnor_6.01025,906,313 - 25,906,474NCBIRnor6.0
Rnor_5.01025,756,497 - 25,756,658UniSTSRnor5.0
RGSC_v3.41025,778,768 - 25,778,929UniSTSRGSC3.4
Celera1024,737,915 - 24,738,076UniSTS
RH 3.4 Map10255.01UniSTS
Cytogenetic Map10q12UniSTS
RH140678  
Rat AssemblyChrPosition (strand)SourceJBrowse
mRatBN7.21025,176,620 - 25,176,828 (+)MAPPERmRatBN7.2
Rnor_6.01025,904,315 - 25,904,522NCBIRnor6.0
Rnor_5.01025,754,499 - 25,754,706UniSTSRnor5.0
RGSC_v3.41025,776,770 - 25,776,977UniSTSRGSC3.4
Celera1024,735,917 - 24,736,124UniSTS
RH 3.4 Map10254.41UniSTS
Cytogenetic Map10q12UniSTS
Ccng1  
Rat AssemblyChrPosition (strand)SourceJBrowse
GRCr81025,680,558 - 25,681,058 (+)Marker Load Pipeline
mRatBN7.21025,178,286 - 25,178,786 (+)MAPPERmRatBN7.2
Rnor_6.01025,905,981 - 25,906,480NCBIRnor6.0
Rnor_5.01025,756,165 - 25,756,664UniSTSRnor5.0
RGSC_v3.41025,778,436 - 25,778,935UniSTSRGSC3.4
Celera1024,737,583 - 24,738,082UniSTS
RH 3.4 Map10255.21UniSTS
Cytogenetic Map10q12UniSTS
BE096914  
Rat AssemblyChrPosition (strand)SourceJBrowse
mRatBN7.21025,179,493 - 25,179,693 (+)MAPPERmRatBN7.2
Rnor_6.01025,907,188 - 25,907,387NCBIRnor6.0
Rnor_5.01025,757,372 - 25,757,571UniSTSRnor5.0
RGSC_v3.41025,779,644 - 25,779,843UniSTSRGSC3.4
Celera1024,738,790 - 24,738,989UniSTS
RH 3.4 Map10256.73UniSTS
Cytogenetic Map10q12UniSTS
Ccng  
Rat AssemblyChrPosition (strand)SourceJBrowse
mRatBN7.21025,178,358 - 25,178,479 (+)MAPPERmRatBN7.2
Rnor_6.01025,906,053 - 25,906,173NCBIRnor6.0
Rnor_5.01025,756,237 - 25,756,357UniSTSRnor5.0
RGSC_v3.41025,778,508 - 25,778,628UniSTSRGSC3.4
Celera1024,737,655 - 24,737,775UniSTS
Cytogenetic Map10q12UniSTS




alimentary part of gastrointestinal system
appendage
circulatory system
ectoderm
endocrine system
endoderm
exocrine system
hemolymphoid system
hepatobiliary system
integumental system
mesenchyme
mesoderm
nervous system
renal system
reproductive system
respiratory system
9 11 49 113 91 90 59 25 59 6 218 97 93 45 60 31



Ensembl Acc Id: ENSRNOT00000065633   ⟹   ENSRNOP00000063905
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.2 Ensembl1025,176,234 - 25,181,641 (-)Ensembl
Rnor_6.0 Ensembl1025,903,925 - 25,910,298 (-)Ensembl
Ensembl Acc Id: ENSRNOT00000079646   ⟹   ENSRNOP00000073529
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
Rnor_6.0 Ensembl1025,903,911 - 25,910,325 (-)Ensembl
RefSeq Acc Id: NM_012923   ⟹   NP_037055
RefSeq Status: VALIDATED
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr81025,678,503 - 25,684,876 (-)NCBI
mRatBN7.21025,176,231 - 25,182,604 (-)NCBI
Rnor_6.01025,903,925 - 25,910,298 (-)NCBI
Rnor_5.01025,754,109 - 25,760,482 (-)NCBI
RGSC_v3.41025,776,380 - 25,782,754 (-)RGD
Celera1024,735,527 - 24,741,900 (-)RGD
Sequence:
Protein RefSeqs NP_037055 (Get FASTA)   NCBI Sequence Viewer  
GenBank Protein AAH81852 (Get FASTA)   NCBI Sequence Viewer  
  CAA50219 (Get FASTA)   NCBI Sequence Viewer  
  EDM04116 (Get FASTA)   NCBI Sequence Viewer  
  EDM04117 (Get FASTA)   NCBI Sequence Viewer  
Ensembl Protein ENSRNOP00000063905
  ENSRNOP00000063905.1
GenBank Protein P39950 (Get FASTA)   NCBI Sequence Viewer  
RefSeq Acc Id: NP_037055   ⟸   NM_012923
- UniProtKB: P39950 (UniProtKB/Swiss-Prot),   A6HDL0 (UniProtKB/TrEMBL),   A6HDL2 (UniProtKB/TrEMBL)
- Sequence:
Ensembl Acc Id: ENSRNOP00000073529   ⟸   ENSRNOT00000079646
Ensembl Acc Id: ENSRNOP00000063905   ⟸   ENSRNOT00000065633
Cyclin-like

Name Modeler Protein Id AA Range Protein Structure
AF-P39950-F1-model_v2 AlphaFold P39950 1-294 view protein structure


eQTL   View at Phenogen
WGCNA   View at Phenogen
Tissue/Strain Expression   View at Phenogen

RGD ID:13697109
Promoter ID:EPDNEW_R7634
Type:multiple initiation site
Name:Ccng1_1
Description:cyclin G1
SO ACC ID:SO:0000170
Source:EPDNEW (Eukaryotic Promoter Database, http://epd.vital-it.ch/)
Experiment Methods:Single-end sequencing.
Position:
Rat AssemblyChrPosition (strand)Source
Rnor_6.01025,910,281 - 25,910,341EPDNEW


1 to 23 of 23 rows
Database
Acc Id
Source(s)
BioCyc Gene G2FUF-25489 BioCyc
Ensembl Genes ENSRNOG00000003256 Ensembl, ENTREZGENE, UniProtKB/Swiss-Prot
Ensembl Transcript ENSRNOT00000065633 ENTREZGENE
  ENSRNOT00000065633.4 UniProtKB/Swiss-Prot
Gene3D-CATH Cyclin-like UniProtKB/Swiss-Prot
IMAGE_CLONE IMAGE:7105829 IMAGE-MGC_LOAD
InterPro Cyclin UniProtKB/Swiss-Prot
  Cyclin-like UniProtKB/Swiss-Prot
  Cyclin-like_sf UniProtKB/Swiss-Prot
  Cyclin_N UniProtKB/Swiss-Prot
KEGG Report rno:25405 UniProtKB/Swiss-Prot
MGC_CLONE MGC:93642 IMAGE-MGC_LOAD
NCBI Gene 25405 ENTREZGENE
PANTHER PTHR10177 UniProtKB/Swiss-Prot
Pfam Cyclin_N UniProtKB/Swiss-Prot
PhenoGen Ccng1 PhenoGen
RatGTEx ENSRNOG00000003256 RatGTEx
SMART CYCLIN UniProtKB/Swiss-Prot
Superfamily-SCOP SSF47954 UniProtKB/Swiss-Prot
TIGR TC204012
UniProt A6HDL0 ENTREZGENE, UniProtKB/TrEMBL
  A6HDL2 ENTREZGENE, UniProtKB/TrEMBL
  CCNG1_RAT UniProtKB/Swiss-Prot, ENTREZGENE
1 to 23 of 23 rows


Date Current Symbol Current Name Previous Symbol Previous Name Description Reference Status
2002-06-10 Ccng1  Cyclin G1      Symbol and Name status set to approved 70586 APPROVED

Note Type Note Reference
gene_domains contains N-terminal cyclin box, but no PEST sequence; contains C-terminal sequence similar to tyrosine phosphorylation site of epidermal growth factor receptor 68222
gene_homology phylogenetically related to HCS26 of S. cerevisiae; most closely resembles Cig1 B-type cyclin of S. pombe 68222
gene_process may be involved in cellular growth stimuli but appears not to be involved in cell cycle 68222
gene_protein 294 amino acids 634709