Gene: Wwc1 (WW and C2 domain containing 1) Rattus norvegicus
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Symbol: Wwc1
Name: WW and C2 domain containing 1
Description: ENCODES a protein that exhibits protein binding, bridging; kinase binding (ortholog); molecular adaptor activity (ortholog); INVOLVED IN cell migration; negative regulation of hippo signaling (ortholog); negative regulation of organ growth (ortholog); ASSOCIATED WITH malignant mesothelioma (ortholog); FOUND IN protein-containing complex; cytoplasm (ortholog); cytosol (ortholog); INTERACTS WITH 2,3,7,8-tetrachlorodibenzodioxine; atrazine; cobalt dichloride
AGR Description: Exhibits protein binding activity, bridging; involved in cell migration; localizes to the protein-containing complex; orthologous to human WWC1 (WW and C2 domain containing 1).
Merged Description: Exhibits protein binding activity, bridging; involved in cell migration; localizes to the protein-containing complex; orthologous to human WWC1 (WW and C2 domain containing 1); INTERACTS WITH 2,3,7,8-tetrachlorodibenzodioxine; atrazine; cobalt dichloride.
Type: protein-coding
RefSeq Status: MODEL
Also known as: LOC303039; protein KIBRA; RGD1308329; similar to KIAA0869 protein; WW, C2 and coiled-coil domain containing 1
Orthologs:
Homo sapiens (human) : WWC1 (WW and C2 domain containing 1)  HGNC  Alliance
Mus musculus (house mouse) : Wwc1 (WW, C2 and coiled-coil domain containing 1)  MGI  Alliance
Chinchilla lanigera (long-tailed chinchilla) : Wwc1 (WW and C2 domain containing 1)
Pan paniscus (bonobo/pygmy chimpanzee) : WWC1 (WW and C2 domain containing 1)
Canis lupus familiaris (dog) : WWC1 (WW and C2 domain containing 1)
Ictidomys tridecemlineatus (thirteen-lined ground squirrel) : Wwc1 (WW and C2 domain containing 1)
Sus scrofa (pig) : WWC1 (WW and C2 domain containing 1)
more info ...
Latest Assembly: Rnor_6.0 - RGSC Genome Assembly v6.0
Position:
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Rnor_6.01020,662,996 - 20,818,500 (-)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_5.01020,535,256 - 20,689,364 (-)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.41020,750,770 - 20,910,298 (-)NCBIRGSC3.4rn4RGSC3.4
RGSC_v3.11020,751,819 - 20,911,409 (-)NCBI
Celera1019,920,851 - 20,074,311 (-)NCBICelera
Cytogenetic Map10q12NCBI
JBrowse: View Region in Genome Browser (JBrowse)
Model


Disease Annotations
Gene-Chemical Interaction Annotations
Gene Ontology Annotations
References - curated
References - uncurated
RGD Disease Portals

Genomics

Candidate Gene Status
Comparative Map Data
Position Markers
QTLs in Region (Rnor_6.0)
miRNA Target Status

Sequence

Nucleotide Sequences
Protein Sequences
Transcriptome

Strain Variation

Strain Sequence Variants (Rnor 5.0)
Damaging Variants

Additional Information

External Database Links
Nomenclature History
 
More on Wwc1
Alliance Gene
NCBI Gene
Ensembl Gene
JBrowse: rn5 rn6
NCBI Genome Data Viewer

RGD Object Information
RGD ID: 1308329
Created: 2005-01-12
Species: Rattus norvegicus
Last Modified: 2019-04-12
Status: ACTIVE



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RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.