Gene: Adra1b (adrenoceptor alpha 1B) Rattus norvegicus
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Symbol: Adra1b
Name: adrenoceptor alpha 1B
Description: Exhibits alpha1-adrenergic receptor activity; involved in several processes, including negative regulation of Rho protein signal transduction, positive regulation of cytosolic calcium ion concentration, and response to drug; localizes to the T-tubule and intercalated disc; biomarker of polycystic ovary syndrome; orthologous to human ADRA1B (adrenoceptor alpha 1B); PARTICIPATES IN G protein mediated signaling pathway via Galphaq family; calcium/calcium-mediated signaling pathway; INTERACTS WITH 1-naphthyl isothiocyanate; 17beta-estradiol; 2,2',5,5'-tetrachlorobiphenyl.
Type: protein-coding
RefSeq Status: PROVISIONAL
Also known as: adrenergic alpha 1B receptor; Adrenergic alpha 1B- receptor; adrenergic receptor, alpha 1b; adrenergic, alpha 1B, receptor; Adrenergic, alpha 1B-, receptor; adrenergic, alpha-1B-, receptor; alpha 1B-adrenoceptor; alpha 1B-adrenoreceptor; alpha-1B adrenergic receptor; alpha-1B adrenoceptor; alpha-1B adrenoreceptor
Orthologs:
Homo sapiens (human) : ADRA1B (adrenoceptor alpha 1B)  HGNC  Alliance
Mus musculus (house mouse) : Adra1b (adrenergic receptor, alpha 1b)  MGI  Alliance
Chinchilla lanigera (long-tailed chinchilla) : Adra1b (adrenoceptor alpha 1B)
Pan paniscus (bonobo/pygmy chimpanzee) : ADRA1B (adrenoceptor alpha 1B)
Canis lupus familiaris (dog) : ADRA1B (adrenoceptor alpha 1B)
Ictidomys tridecemlineatus (thirteen-lined ground squirrel) : Adra1b (adrenoceptor alpha 1B)
Sus scrofa (pig) : ADRA1B (adrenoceptor alpha 1B)
more info ...
Latest Assembly: Rnor_6.0 - RGSC Genome Assembly v6.0
Position:
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Rnor_6.01029,392,762 - 29,450,644 (-)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_5.01029,233,972 - 29,291,344 (-)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.41028,889,092 - 28,946,889 (-)NCBIRGSC3.4rn4RGSC3.4
RGSC_v3.11028,890,140 - 28,947,938 (-)NCBI
Celera1027,744,674 - 27,802,198 (-)NCBICelera
Cytogenetic Map10q21NCBI
JBrowse: View Region in Genome Browser (JBrowse)
Model


Disease Annotations
Gene-Chemical Interaction Annotations
Gene Ontology Annotations
Molecular Pathway Annotations
References - curated
References - uncurated
RGD Disease Portals

Genomics

Comparative Map Data
Position Markers
QTLs in Region (Rnor_6.0)

Sequence

Nucleotide Sequences
Protein Sequences
Promoters

Strain Variation

Strain Sequence Variants (Rnor 5.0)

Additional Information

External Database Links
Nomenclature History
RGD Curation Notes
 
More on Adra1b
Alliance Gene
NCBI Gene
Ensembl Gene
JBrowse: rn5 rn6
NCBI Genome Data Viewer

RGD Object Information
RGD ID: 2054
Created: 2000-05-25
Species: Rattus norvegicus
Last Modified: 2019-04-23
Status: ACTIVE



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RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.