Gene: Haspin (histone H3 associated protein kinase) Rattus norvegicus
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Symbol: Haspin
Name: histone H3 associated protein kinase
Description: ENCODES a protein that exhibits ATP binding (ortholog); DNA binding (ortholog); histone kinase activity (H3-T3 specific) (ortholog); INVOLVED IN histone H3-T3 phosphorylation involved in chromosome passenger complex localization to kinetochore (ortholog); intracellular signal transduction (ortholog); mitotic sister chromatid cohesion (ortholog); ASSOCIATED WITH Canavan disease (ortholog); FOUND IN centrosome (ortholog); nucleus (ortholog); spindle (ortholog); INTERACTS WITH 6-propyl-2-thiouracil; bisphenol A; (-)-demecolcine (ortholog)
AGR Description: Predicted to have ATP binding activity, DNA binding activity, and histone kinase activity (H3-T3 specific); predicted to be involved in several processes, including histone H3-T3 phosphorylation involved in chromosome passenger complex localization to kinetochore, intracellular signal transduction, and mitotic sister chromatid cohesion; predicted to localize to the cytoplasm and intracellular organelle; orthologous to human HASPIN (histone H3 associated protein kinase).
Merged Description: Predicted to have ATP binding activity, DNA binding activity, and histone kinase activity (H3-T3 specific); predicted to be involved in several processes, including histone H3-T3 phosphorylation involved in chromosome passenger complex localization to kinetochore, intracellular signal transduction, and mitotic sister chromatid cohesion; predicted to localize to the cytoplasm and intracellular organelle; orthologous to human HASPIN (histone H3 associated protein kinase); INTERACTS WITH 6-propyl-2-thiouracil; bisphenol A; (-)-demecolcine (ortholog).
Type: protein-coding
RefSeq Status: MODEL
Also known as: germ cell associated 2 (haspin); Gsg2; LOC687827; serine/threonine-protein kinase haspin; similar to Serine/threonine-protein kinase Haspin (Haploid germ cell-specific nuclear protein kinase) (Germ cell-specific gene 2 protein)
Orthologs:
Homo sapiens (human) : HASPIN (histone H3 associated protein kinase)  HGNC  Alliance
Mus musculus (house mouse) : Haspin (histone H3 associated protein kinase)  MGI  Alliance
Chinchilla lanigera (long-tailed chinchilla) : Haspin (histone H3 associated protein kinase)
Pan paniscus (bonobo/pygmy chimpanzee) : HASPIN (histone H3 associated protein kinase)
Canis lupus familiaris (dog) : HASPIN (histone H3 associated protein kinase)
Ictidomys tridecemlineatus (thirteen-lined ground squirrel) : Haspin (histone H3 associated protein kinase)
Sus scrofa (pig) : HASPIN (histone H3 associated protein kinase)
more info ...
Latest Assembly: Rnor_6.0 - RGSC Genome Assembly v6.0
Position:
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Rnor_6.01059,695,403 - 59,698,398 (-)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_5.01059,434,870 - 59,437,669 (-)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
Celera1056,871,875 - 56,874,870 (-)NCBICelera
Cytogenetic Map10q24NCBI
JBrowse: View Region in Genome Browser (JBrowse)
Model


Disease Annotations
Gene-Chemical Interaction Annotations
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References - curated
References - uncurated
RGD Disease Portals

Genomics

Comparative Map Data
Position Markers
QTLs in Region (Rnor_6.0)
miRNA Target Status

Sequence

Nucleotide Sequences
Protein Sequences
Transcriptome
Promoters

Strain Variation

Strain Sequence Variants (Rnor 5.0)
Damaging Variants

Additional Information

External Database Links
Nomenclature History
 
More on Haspin
Alliance Gene
NCBI Gene
Ensembl Gene
JBrowse: rn5 rn6
NCBI Genome Data Viewer

RGD Object Information
RGD ID: 1596276
Created: 2006-11-20
Species: Rattus norvegicus
Last Modified: 2019-04-12
Status: ACTIVE



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RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.