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Gene: Myh3 (myosin heavy chain 3) Rattus norvegicus
Symbol: Myh3
Name: myosin heavy chain 3
RGD ID: 3138
Description: Predicted to have ATPase activity; actin filament binding activity; and microfilament motor activity. Predicted to be involved in ATP metabolic process and skeletal muscle contraction. Predicted to localize to contractile fiber and myosin complex. Human ortholog(s) of this gene implicated in distal arthrogryposis type 2A; distal arthrogryposis type 2B1; and distal arthrogryposis type 2B3. Orthologous to human MYH3 (myosin heavy chain 3); PARTICIPATES IN myocarditis pathway; INTERACTS WITH 2,3,7,8-tetrachlorodibenzodioxine; 2,3,7,8-Tetrachlorodibenzofuran; 6-propyl-2-thiouracil.
Type: protein-coding
Also known as: Myhse; myosin heavy chain, fast skeletal muscle, embryonic; myosin heavy polypeptide 3; Myosin heavy polypeptide 3 skeletal muscle embryonic; myosin, heavy chain 3, skeletal muscle, embryonic; myosin, heavy polypeptide 3; Myosin, heavy polypeptide 3, skeletal muscle, embryonic; myosin-3; RNMHCG
Homo sapiens (human) : MYH3 (myosin heavy chain 3)  HGNC  Alliance
Mus musculus (house mouse) : Myh3 (myosin, heavy polypeptide 3, skeletal muscle, embryonic)  MGI  Alliance
Chinchilla lanigera (long-tailed chinchilla) : LOC102003853 (myosin-3)
Pan paniscus (bonobo/pygmy chimpanzee) : MYH3 (myosin heavy chain 3)
Canis lupus familiaris (dog) : MYH3 (myosin heavy chain 3)
Ictidomys tridecemlineatus (thirteen-lined ground squirrel) : LOC101974020 (myosin-3)
Sus scrofa (pig) : MYH3 (myosin heavy chain 3)
Chlorocebus sabaeus (African green monkey) : MYH3 (myosin heavy chain 3)
Heterocephalus glaber (naked mole-rat) : LOC101698672 (myosin-3)
more info ...
Is Marker For: QTLs:   Bp1   Btemp1   Hpcl1  
Latest Assembly: Rnor_6.0 - RGSC Genome Assembly v6.0
Rat AssemblyChrPosition (strand)SourceGenome Browsers
Rnor_6.01053,621,375 - 53,645,194 (+)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl1053,621,375 - 53,645,194 (+)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.01053,372,408 - 53,396,227 (+)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.41053,776,858 - 53,800,677 (+)NCBIRGSC3.4rn4RGSC3.4
RGSC_v3.11053,790,480 - 53,814,300 (+)NCBI
Celera1050,953,285 - 50,977,099 (+)NCBICelera
Cytogenetic Map10q24NCBI
JBrowse: View Region in Genome Browser (JBrowse)

Disease Annotations
Gene-Chemical Interaction Annotations
Gene Ontology Annotations
Molecular Pathway Annotations
References - curated
References - uncurated


Candidate Gene Status
Comparative Map Data
Position Markers
QTLs in Region (Rnor_6.0)
miRNA Target Status


RNA-SEQ Expression


Nucleotide Sequences
Protein Sequences

Strain Variation

Strain Sequence Variants (Rnor 6.0)

Additional Information

External Database Links
Nomenclature History
RGD Curation Notes
More on Myh3
Alliance Gene
Ensembl Gene
JBrowse: rn5 rn6
NCBI Genome Data Viewer

RGD Object Information
RGD ID: 3138
Created: 2000-05-25
Species: Rattus norvegicus
Last Modified: 2020-08-20
Status: ACTIVE


RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.