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Gene: Serpinf1 (serpin family F member 1) Rattus norvegicus
Symbol: Serpinf1
Name: serpin family F member 1
RGD ID: 631369
Description: Predicted to have serine-type endopeptidase inhibitor activity. Involved in several processes, including cellular response to glucose stimulus; cellular response to lipid; and short-term memory. Localizes to several cellular components, including axon hillock; basement membrane; and perinuclear region of cytoplasm. Used to study Alzheimer's disease; middle cerebral artery infarction; and type 2 diabetes mellitus. Biomarker of endometriosis; obesity; portal hypertension; retinal disease (multiple); and type 2 diabetes mellitus. Human ortholog(s) of this gene implicated in several diseases, including bone disease (multiple); brain edema; eye disease (multiple); leukostasis; and non-alcoholic steatohepatitis. Orthologous to human SERPINF1 (serpin family F member 1); INTERACTS WITH 17alpha-ethynylestradiol; 2,3,7,8-tetrachlorodibenzodioxine; 2,6-dinitrotoluene.
Type: protein-coding
Also known as: alpha-2 antiplasmin; Dmrs91; Pedf; pigment epithelium-derived factor; serine (or cysteine) peptidase inhibitor, clade F, member 1; serine (or cysteine) proteinase inhibitor, clade F), member 1; serine (or cysteine) proteinase inhibitor, clade F, member 1; serpin peptidase inhibitor, clade F (alpha-2 antiplasmin, pigment epithelium derived factor), member 1; sserpin family F member 1
Homo sapiens (human) : SERPINF1 (serpin family F member 1)  HGNC  Alliance
Mus musculus (house mouse) : Serpinf1 (serine (or cysteine) peptidase inhibitor, clade F, member 1)  MGI  Alliance
Chinchilla lanigera (long-tailed chinchilla) : Serpinf1 (serpin family F member 1)
Pan paniscus (bonobo/pygmy chimpanzee) : SERPINF1 (serpin family F member 1)
Canis lupus familiaris (dog) : SERPINF1 (serpin family F member 1)
Ictidomys tridecemlineatus (thirteen-lined ground squirrel) : Serpinf1 (serpin family F member 1)
Sus scrofa (pig) : SERPINF1 (serpin family F member 1)
Chlorocebus sabaeus (African green monkey) : SERPINF1 (serpin family F member 1)
Heterocephalus glaber (naked mole-rat) : Serpinf1 (serpin family F member 1)
more info ...
Latest Assembly: Rnor_6.0 - RGSC Genome Assembly v6.0
Rat AssemblyChrPosition (strand)SourceGenome Browsers
Rnor_6.01062,241,750 - 62,254,145 (-)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl1062,241,756 - 62,254,287 (-)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.01061,954,919 - 61,969,094 (-)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.41062,713,441 - 62,739,444 (-)NCBIRGSC3.4rn4RGSC3.4
RGSC_v3.11062,727,065 - 62,753,067 (-)NCBI
Celera1059,279,849 - 59,291,539 (-)NCBICelera
Cytogenetic Map10q24NCBI
JBrowse: View Region in Genome Browser (JBrowse)

Disease Annotations
Gene-Chemical Interaction Annotations
Gene Ontology Annotations
References - curated
References - uncurated


Comparative Map Data
Position Markers
QTLs in Region (Rnor_6.0)
miRNA Target Status


RNA-SEQ Expression


Nucleotide Sequences
Protein Sequences

Strain Variation

Strain Sequence Variants (Rnor 6.0)

Additional Information

External Database Links
Nomenclature History
More on Serpinf1
Alliance Gene
Ensembl Gene
JBrowse: rn5 rn6
NCBI Genome Data Viewer

RGD Object Information
RGD ID: 631369
Created: 2003-08-13
Species: Rattus norvegicus
Last Modified: 2020-08-20
Status: ACTIVE


RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.