Serpinf1 (serpin family F member 1) - Rat Genome Database

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Gene: Serpinf1 (serpin family F member 1) Rattus norvegicus
Analyze
Symbol: Serpinf1
Name: serpin family F member 1
RGD ID: 631369
Description: Predicted to enable serine-type endopeptidase inhibitor activity. Involved in several processes, including cellular response to glucose stimulus; cellular response to lipid; and short-term memory. Located in several cellular components, including axon hillock; basement membrane; and perinuclear region of cytoplasm. Used to study Alzheimer's disease; middle cerebral artery infarction; and type 2 diabetes mellitus. Biomarker of endometriosis; obesity; portal hypertension; retinal disease (multiple); and type 2 diabetes mellitus. Human ortholog(s) of this gene implicated in several diseases, including brain edema; eye disease (multiple); leukostasis; non-alcoholic steatohepatitis; and osteogenesis imperfecta type 6. Orthologous to human SERPINF1 (serpin family F member 1); INTERACTS WITH 17alpha-ethynylestradiol; 2,3,7,8-tetrachlorodibenzodioxine; 2,6-dinitrotoluene.
Type: protein-coding
RefSeq Status: PROVISIONAL
Also known as: alpha-2 antiplasmin; Dmrs91; Pedf; pigment epithelium-derived factor; serine (or cysteine) peptidase inhibitor, clade F, member 1; serine (or cysteine) proteinase inhibitor, clade F), member 1; serine (or cysteine) proteinase inhibitor, clade F, member 1; serpin peptidase inhibitor, clade F (alpha-2 antiplasmin, pigment epithelium derived factor), member 1; sserpin family F member 1
RGD Orthologs
Human
Mouse
Chinchilla
Bonobo
Dog
Squirrel
Pig
Green Monkey
Naked Mole-Rat
Alliance Genes
More Info more info ...
Latest Assembly: mRatBN7.2 - mRatBN7.2 Assembly
Position:
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
mRatBN7.21060,250,198 - 60,262,593 (-)NCBImRatBN7.2
mRatBN7.2 Ensembl1060,249,708 - 60,262,646 (-)Ensembl
Rnor_6.01062,241,750 - 62,254,145 (-)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl1062,241,756 - 62,254,287 (-)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.01061,954,919 - 61,969,094 (-)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.41062,713,441 - 62,739,444 (-)NCBIRGSC3.4rn4RGSC3.4
RGSC_v3.11062,727,065 - 62,753,067 (-)NCBI
Celera1059,279,849 - 59,291,539 (-)NCBICelera
Cytogenetic Map10q24NCBI
JBrowse: View Region in Genome Browser (JBrowse)
Model


Disease Annotations     Click to see Annotation Detail View
adenoid cystic carcinoma  (ISO)
Albuminuria  (ISO)
Alcoholic Fatty Liver  (IEP)
alcoholic liver cirrhosis  (ISO)
Alzheimer's disease  (IDA,ISO)
amyotrophic lateral sclerosis  (ISO)
anogenital venereal wart  (ISO)
Arterial Thrombosis  (ISO)
brain edema  (ISO)
Brain Injuries  (IEP,ISO)
Carotid Artery Injuries  (ISO)
central retinal vein occlusion  (IEP)
Choroidal Neovascularization  (IEP,ISO)
chronic fatigue syndrome  (ISO)
corneal neovascularization  (ISO)
corneal ulcer  (ISO)
diabetic angiopathy  (ISO)
Diabetic Nephropathies  (IEP,ISO)
diabetic retinopathy  (IEP,ISO)
endometriosis  (IEP,ISO)
Endotoxemia  (ISO)
Endotoxin-Induced Uveitis  (IEP)
Experimental Diabetes Mellitus  (IEP)
hepatocellular carcinoma  (ISO)
hepatosplenic schistosomiasis  (ISO)
Hirschsprung Disease 1  (ISO)
Hypoxia  (IEP)
Inflammation  (ISO)
Insulin Resistance  (IDA,ISO)
Keloid  (ISO)
kidney failure  (ISO)
leukostasis  (ISO)
lung non-small cell carcinoma  (ISO)
macular degeneration  (IEP,ISO)
macular retinal edema  (ISO)
melioidosis  (ISO)
middle cerebral artery infarction  (IDA)
Myocardial Ischemia  (ISO)
Neoplasm Metastasis  (IEP)
neovascular inflammatory vitreoretinopathy  (ISO)
nephroblastoma  (ISO)
non-alcoholic steatohepatitis  (ISO)
obesity  (IEP,ISO)
Olfaction Disorders  (IEP)
Osteoarthritis, Experimental  (ISO)
osteogenesis imperfecta  (ISO)
osteogenesis imperfecta type 3  (ISO)
osteogenesis imperfecta type 6  (ISO)
osteosarcoma  (ISO)
ovarian hyperstimulation syndrome  (ISO)
Oxygen-Induced Retinopathy  (IEP,ISO)
Parkinson's disease  (ISO)
Peripheral Nerve Injuries  (IEP)
portal hypertension  (IEP)
proliferative diabetic retinopathy  (ISO)
Prostatic Neoplasms  (ISO)
Retina Reperfusion Injury  (ISO)
retinal degeneration  (ISO)
Retinal Neovascularization  (ISO)
retinal vein occlusion  (ISO)
retinitis pigmentosa  (ISO)
retinoblastoma  (ISO)
retinopathy of prematurity  (IEP)
Salivary Gland Neoplasms  (ISO)
sciatic neuropathy  (ISO)
Septic Peritonitis  (ISO)
Sickle Cell Retinopathy  (ISO)
Staphylococcal Skin Infections  (ISO)
toxic shock syndrome  (ISO)
transient cerebral ischemia  (ISO)
type 1 diabetes mellitus  (ISO)
type 2 diabetes mellitus  (IEP,IMP,ISO)
uveal melanoma  (ISO)
uveitis  (ISO)
venous tributary occlusion of retina  (ISO)

Gene-Chemical Interaction Annotations     Click to see Annotation Detail View
(S)-nicotine  (ISO)
1,1-dichloroethene  (ISO)
1,2-dichloroethane  (ISO)
1,2-dimethylhydrazine  (ISO)
17alpha-ethynylestradiol  (EXP,ISO)
17beta-estradiol  (ISO)
2,2',4,4'-Tetrabromodiphenyl ether  (ISO)
2,3,7,8-tetrachlorodibenzodioxine  (EXP,ISO)
2,6-dinitrotoluene  (EXP)
2-acetamidofluorene  (ISO)
2-butoxyethanol  (ISO)
2-hydroxypropanoic acid  (ISO)
3-chloropropane-1,2-diol  (EXP)
3-isobutyl-1-methyl-7H-xanthine  (ISO)
3H-1,2-dithiole-3-thione  (EXP)
4,4'-sulfonyldiphenol  (ISO)
4-hydroxyphenyl retinamide  (ISO)
6-propyl-2-thiouracil  (EXP)
acetamide  (EXP)
aconitine  (EXP)
adrenaline  (ISO)
aflatoxin B1  (ISO)
aldehydo-D-glucose  (ISO)
all-trans-retinoic acid  (EXP,ISO)
ammonium chloride  (EXP)
aristolochic acid  (ISO)
arsane  (ISO)
arsenic atom  (ISO)
atrazine  (ISO)
benzene-1,2,4-triol  (ISO)
benzo[a]pyrene  (ISO)
benzo[b]fluoranthene  (ISO)
bis(2-ethylhexyl) phthalate  (ISO)
bisphenol A  (EXP,ISO)
bisphenol F  (ISO)
cadmium atom  (EXP)
cadmium dichloride  (EXP)
calcitriol  (ISO)
carbon nanotube  (ISO)
ceruletide  (EXP)
cisplatin  (ISO)
clofibrate  (ISO)
cobalt dichloride  (EXP,ISO)
copper atom  (EXP,ISO)
copper(0)  (EXP,ISO)
copper(II) chloride  (ISO)
copper(II) sulfate  (ISO)
cyclosporin A  (ISO)
cylindrospermopsin  (ISO)
cyproconazole  (EXP)
D-glucose  (ISO)
dexamethasone  (EXP,ISO)
dibutyl phthalate  (EXP)
diuron  (EXP)
dorsomorphin  (ISO)
doxorubicin  (ISO)
elemental selenium  (ISO)
ethanol  (ISO)
fenamidone  (ISO)
flusilazole  (EXP)
furosemide  (EXP)
gefitinib  (ISO)
glafenine  (EXP)
glucose  (ISO)
indometacin  (ISO)
mancozeb  (ISO)
methylmercury chloride  (ISO)
methylseleninic acid  (ISO)
mifepristone  (EXP,ISO)
morphine  (ISO)
N-methyl-4-phenylpyridinium  (ISO)
N-nitrosodiethylamine  (EXP,ISO)
N-Nitrosopyrrolidine  (ISO)
nicotine  (ISO)
O-methyleugenol  (ISO)
oxaliplatin  (EXP)
paclitaxel  (ISO)
panobinostat  (ISO)
paracetamol  (ISO)
pentane-2,3-dione  (EXP)
perfluorononanoic acid  (ISO)
perfluorooctanoic acid  (EXP,ISO)
phenethyl caffeate  (EXP)
pirinixic acid  (EXP)
potassium dichromate  (ISO)
progesterone  (ISO)
propranolol  (ISO)
quercetin  (ISO)
rac-lactic acid  (ISO)
resveratrol  (ISO)
rotenone  (EXP)
SB 431542  (ISO)
Securinine  (ISO)
selenium atom  (ISO)
silicon dioxide  (EXP,ISO)
sodium arsenite  (EXP,ISO)
sodium fluoride  (EXP)
sodium taurocholate  (EXP)
Soman  (EXP)
sunitinib  (ISO)
tetrachloromethane  (EXP,ISO)
thapsigargin  (ISO)
titanium dioxide  (ISO)
topotecan  (EXP)
triadimefon  (EXP)
trichloroethene  (ISO)
trichostatin A  (ISO)
troglitazone  (ISO)
tunicamycin  (ISO)
valdecoxib  (EXP)
valproic acid  (EXP,ISO)
vitamin E  (ISO)
vorinostat  (ISO)

Gene Ontology Annotations     Click to see Annotation Detail View

Cellular Component

Molecular Function

References

References - curated
1. Abramson LP, etal., J Pediatr Surg. 2006 Aug;41(8):1351-6.
2. Amaral J and Becerra SP, Invest Ophthalmol Vis Sci. 2010 Mar;51(3):1318-26. doi: 10.1167/iovs.09-4455. Epub 2009 Oct 22.
3. Awad AS, etal., Am J Physiol Renal Physiol. 2013 Sep 15;305(6):F891-900. doi: 10.1152/ajprenal.00149.2013. Epub 2013 Jul 24.
4. Baraniuk JN, etal., BMC Neurol. 2005 Dec 1;5:22. doi: 10.1186/1471-2377-5-22.
5. Bhutto IA, etal., Exp Eye Res. 2006 Jan;82(1):99-110. Epub 2005 Jul 12.
6. Bilak MM, etal., J Neuropathol Exp Neurol. 1999 Jul;58(7):719-28.
7. Calenda G, etal., BJU Int. 2012 May;109(10):1552-64. doi: 10.1111/j.1464-410X.2011.10705.x. Epub 2012 Feb 2.
8. Cayouette M, etal., Neurobiol Dis. 1999 Dec;6(6):523-32.
9. Chavan SS, etal., Mol Med. 2012 Oct 24;18:1161-8. doi: 10.2119/molmed.2012.00156.
10. Chuderland D, etal., Hum Reprod. 2013 Jun;28(6):1626-34. doi: 10.1093/humrep/det027. Epub 2013 Mar 6.
11. Chuderland D, etal., J Clin Endocrinol Metab. 2013 Feb;98(2):E258-66. doi: 10.1210/jc.2012-3037. Epub 2013 Jan 7.
12. Chung C, etal., Gastroenterology. 2009 Jan;136(1):331-340.e2. Epub 2008 Oct 7.
13. Cohen MP, etal., Ophthalmic Res. 2008;40(1):5-9. Epub 2007 Nov 20.
14. Crawford SE, etal., J Cell Sci. 2001 Dec;114(Pt 24):4421-8.
15. de Jong HK, etal., J Thromb Haemost. 2015 Jan;13(1):41-6. doi: 10.1111/jth.12776. Epub 2014 Dec 6.
16. Dong YH, etal., J Int Med Res. 2013 Apr;41(2):365-70. doi: 10.1177/0300060513476584. Epub 2013 Mar 14.
17. Duh EJ, etal., Am J Ophthalmol. 2004 Apr;137(4):668-74.
18. Duh EJ, etal., Invest Ophthalmol Vis Sci. 2002 Mar;43(3):821-9.
19. Ek ET, etal., Cancer Gene Ther. 2007 Jul;14(7):616-26. Epub 2007 May 4.
20. Ek ET, etal., Clin Exp Metastasis. 2007;24(2):93-106. Epub 2007 Apr 18.
21. el-Bassiouni NE, etal., J Clin Pathol. 1996 Dec;49(12):990-3. doi: 10.1136/jcp.49.12.990.
22. Feher J, etal., Invest Ophthalmol Vis Sci. 2009 Nov;50(11):5173-80. doi: 10.1167/iovs.08-1852. Epub 2009 Jun 24.
23. Fu G, etal., Acta Histochem. 2013 May;115(4):301-7. doi: 10.1016/j.acthis.2012.08.006. Epub 2012 Sep 10.
24. Gallimore MJ, etal., Thromb Res. 1980 Jun 1;18(5):601-8. doi: 10.1016/0049-3848(80)90214-5.
25. Gao G, etal., Diabetes. 2002 Apr;51(4):1218-25.
26. Gaudet P, etal., Brief Bioinform. 2011 Sep;12(5):449-62. doi: 10.1093/bib/bbr042. Epub 2011 Aug 27.
27. Halin S, etal., Cancer Res. 2004 Aug 15;64(16):5664-71.
28. Halin S, etal., Neoplasia. 2010 Apr;12(4):336-45.
29. Hartmann JS, etal., Mol Vis. 2011;17:1577-87. Epub 2011 Jun 10.
30. Houenou LJ, etal., J Comp Neurol. 1999 Sep 27;412(3):506-14.
31. Iizuka H, etal., Biochem Biophys Res Commun. 2007 Sep 21;361(2):421-6. Epub 2007 Jul 16.
32. Jenkins A, etal., Diabetes Res Clin Pract. 2008 Oct;82(1):e5-7. Epub 2008 Aug 19.
33. Jenkins AJ, etal., Diabet Med. 2007 Dec;24(12):1345-51. Epub 2007 Oct 29.
34. Jiang R, etal., Medicine (Baltimore). 2019 Oct;98(41):e17478. doi: 10.1097/MD.0000000000017478.
35. Jilma B, etal., Clin Pharmacol Ther. 2002 Oct;72(4):403-10. doi: 10.1067/mcp.2002.127740.
36. Jinnouchi Y, etal., Brain Res. 2007 Sep 5;1167:92-100. Epub 2007 Jul 10.
37. Kager LM, etal., Am J Respir Crit Care Med. 2013 Oct 15;188(8):967-75. doi: 10.1164/rccm.201307-1344OC.
38. Katakami N, etal., Diabetes Res Clin Pract. 2008 Jul;81(1):e4-7. Epub 2008 May 2.
39. Kim SY, etal., Exp Eye Res. 2003 Oct;77(4):433-45.
40. Kozek E, etal., Rev Diabet Stud. 2004 Fall;1(3):122-8. Epub 2004 Nov 10.
41. Kozlowska J, etal., Saudi J Gastroenterol. 2016 Sep-Oct;22(5):375-379. doi: 10.4103/1319-3767.191143.
42. Kruse P, etal., Int J Pancreatol. 1999 Apr;25(2):113-21.
43. Kruse P, etal., J Surg Res. 1999 Aug;85(2):294-300.
44. Kuncl RW, etal., J Neurochem. 2002 Apr;81(1):178-84.
45. Kuo CN, etal., Exp Eye Res. 2009 Nov;89(5):678-85. doi: 10.1016/j.exer.2009.06.021. Epub 2009 Jul 9.
46. Lang V, etal., J Neurol Sci. 2017 Apr 15;375:123-128. doi: 10.1016/j.jns.2017.01.051. Epub 2017 Jan 17.
47. Lattier JM, etal., Clin Exp Metastasis. 2013 Dec;30(8):969-76. doi: 10.1007/s10585-013-9596-3. Epub 2013 Jun 22.
48. Li H, etal., Exp Eye Res. 2006 Oct;83(4):824-33. Epub 2006 Jul 5.
49. Maik-Rachline G, etal., Blood. 2005 Jan 15;105(2):670-8. Epub 2004 Sep 16.
50. Markovets AM, etal., Aging (Albany NY). 2011 Jan;3(1):44-54.
51. Matsui T, etal., Am J Pathol. 2014 Apr;184(4):1094-103. doi: 10.1016/j.ajpath.2013.12.032. Epub 2014 Feb 13.
52. Matsuno H, etal., Blood 2003 Nov 15;102(10):3621-8. Epub 2003 Jul 31.
53. Matsuoka M, etal., Exp Eye Res. 2006 Jan;82(1):172-8. Epub 2005 Jul 27.
54. Matsuoka M, etal., Mol Vis. 2007 Jun 29;13:1058-65.
55. Matsuyama K, etal., Mol Vis. 2008 May 28;14:992-6.
56. MGD data from the GO Consortium
57. Miyazaki M, etal., J Gene Med. 2008 Dec;10(12):1273-81. doi: 10.1002/jgm.1257.
58. Mori K, etal., Invest Ophthalmol Vis Sci. 2002 Jun;43(6):1994-2000.
59. Mori K, etal., J Cell Physiol. 2001 Aug;188(2):253-63.
60. Mu H, etal., Mol Biol Rep. 2009 Nov;36(8):2147-51. doi: 10.1007/s11033-008-9428-8. Epub 2008 Dec 24.
61. Murakami Y, etal., Hum Gene Ther. 2010 Feb;21(2):199-209. doi: 10.1089/hum.2009.102.
62. Nakamura DS, etal., BMC Musculoskelet Disord. 2017 Jan 25;18(1):39. doi: 10.1186/s12891-017-1410-y.
63. Nakamura K, etal., Am J Pathol. 2007 Jun;170(6):2159-70.
64. Nakamura K, etal., Int J Cardiol. 2008 Dec 13.
65. Noma H, etal., Curr Eye Res. 2011 Mar;36(3):256-63. doi: 10.3109/02713683.2010.513090. Epub 2011 Jan 28.
66. Noma H, etal., Graefes Arch Clin Exp Ophthalmol. 2010 Nov;248(11):1559-65. doi: 10.1007/s00417-010-1486-7. Epub 2010 Aug 17.
67. Oda H, etal., Adv Perit Dial. 2000;16:152-5.
68. OMIM Disease Annotation Pipeline
69. Omri S, etal., Invest Ophthalmol Vis Sci. 2019 Nov 1;60(14):4632-4642. doi: 10.1167/iovs.18-25502.
70. Ong CT, etal., Br J Dermatol. 2010 Jun;162(6):1302-15. doi: 10.1111/j.1365-2133.2010.09660.x. Epub 2010 Feb 1.
71. Pan WD, etal., Hepatogastroenterology. 2011 Nov-Dec;58(112):2152-5. doi: 10.5754/hge11227.
72. Park K, etal., Am J Pathol. 2011 Feb;178(2):688-98. doi: 10.1016/j.ajpath.2010.10.014.
73. Pawlak K, etal., Thromb Res. 2007;119(4):475-80. doi: 10.1016/j.thromres.2006.03.011. Epub 2006 Jul 7.
74. Peetermans M, etal., BMC Microbiol. 2014 Dec 17;14:310. doi: 10.1186/s12866-014-0310-7.
75. Pina AL, etal., Cell Tissue Res. 2007 Aug;329(2):329-38. Epub 2007 May 12.
76. Rehak M, etal., Graefes Arch Clin Exp Ophthalmol. 2011 Aug;249(8):1175-83. Epub 2011 Apr 13.
77. RGD automated data pipeline
78. RGD automated import pipeline for ClinVar variants, variant-to-disease annotations and gene-to-disease annotations
79. RGD automated import pipeline for gene-chemical interactions
80. RGD comprehensive gene curation
81. Rodríguez-Piñeiro AM, etal., J Proteomics. 2010 Jun 16;73(8):1511-22. doi: 10.1016/j.jprot.2010.03.005. Epub 2010 Mar 15.
82. Roet KC, etal., J Neurosci. 2013 Jul 3;33(27):11116-35. doi: 10.1523/JNEUROSCI.1002-13.2013.
83. Sanagi T, etal., J Neurochem. 2008 Aug;106(4):1841-54. doi: 10.1111/j.1471-4159.2008.05529.x. Epub 2008 Jul 4.
84. Sanagi T, etal., J Neuropathol Exp Neurol. 2010 Mar;69(3):224-33. doi: 10.1097/NEN.0b013e3181cfc46f.
85. Sanagi T, etal., Neurosci Lett. 2007 Aug 31;424(1):66-71. Epub 2007 Aug 1.
86. Shi XH, etal., Zhonghua Yan Ke Za Zhi. 2004 Jun;40(6):404-8.
87. Smith CP and Steinle JJ, Exp Eye Res. 2007 Dec;85(6):817-24. Epub 2007 Aug 29.
88. Spranger J, etal., Diabetes. 2001 Dec;50(12):2641-5.
89. Storozheva ZI, etal., Bull Exp Biol Med. 2006 Mar;141(3):319-22.
90. Strausberg RL, etal., Proc Natl Acad Sci U S A. 2002 Dec 24;99(26):16899-903. Epub 2002 Dec 11.
91. Takenaka K, etal., Atherosclerosis. 2008 Mar;197(1):25-33. Epub 2007 Sep 11.
92. Tombran-Tink J, etal., Exp Eye Res. 2004 May;78(5):945-55.
93. Tong JP, etal., Am J Ophthalmol. 2006 Mar;141(3):456-62.
94. Ulrich JN, etal., Clin Exp Ophthalmol. 2008 Jul;36(5):431-6.
95. Unterlauft JD, etal., Neurochem Res. 2012 Jul;37(7):1524-33. doi: 10.1007/s11064-012-0747-8. Epub 2012 Mar 13.
96. van der Poll T, etal., J Exp Med. 1997 Mar 17;185(6):1143-8.
97. van Goor H, etal., Br J Surg. 1996 Aug;83(8):1133-5. doi: 10.1002/bjs.1800830833.
98. Wang JJ, etal., Am J Physiol Renal Physiol. 2008 May;294(5):F1166-73. Epub 2008 Mar 5.
99. Wang JJ, etal., Diabetes 2005 Jan;54(1):243-50.
100. Wang JJ, etal., Diabetes. 2006 Jun;55(6):1678-85.
101. Wang S, etal., Arch Ophthalmol. 2009 Apr;127(4):507-13.
102. Yabe T, etal., Glia. 2005 May;50(3):223-34.
103. Yamagishi S, etal., Microvasc Res. 2006 Jul-Sep;72(1-2):86-90. Epub 2006 Jun 22.
104. Yamagishi SI, etal., Int J Cardiol. 2009 Feb 21.
105. Yang H, etal., Cancer Sci. 2009 Dec;100(12):2419-25. doi: 10.1111/j.1349-7006.2009.01332.x. Epub 2009 Aug 27.
106. Yang M, etal., PLoS One. 2015 Jun 29;10(6):e0131664. doi: 10.1371/journal.pone.0131664. eCollection 2015.
107. Yang S, etal., Endocrinology. 2014 Mar;155(3):941-50. doi: 10.1210/en.2013-1813. Epub 2014 Jan 1.
108. Yang S, etal., Mediators Inflamm. 2013;2013:429207. doi: 10.1155/2013/429207. Epub 2013 Oct 31.
109. Yang XM, etal., J Neurosci Res. 2012 Jan;90(1):257-66. doi: 10.1002/jnr.22732. Epub 2011 Sep 15.
110. Yoshida T, etal., Dig Dis Sci. 2017 Jun;62(6):1527-1536. doi: 10.1007/s10620-017-4550-x. Epub 2017 Apr 1.
111. Yoshida Y, etal., Br J Ophthalmol. 2007 Feb;91(2):149-50. Epub 2006 Sep 14.
112. Yu H, etal., Mol Vis. 2010 Nov 15;16:2384-94.
113. Zhang SX, etal., FASEB J. 2006 Feb;20(2):323-5. Epub 2005 Dec 20.
114. Zhang W, etal., Biol Trace Elem Res. 2013 Feb;151(2):269-76. doi: 10.1007/s12011-012-9558-7. Epub 2012 Dec 11.
115. Zhang Y, etal., Zhonghua Yan Ke Za Zhi. 2007 Dec;43(12):1130-4.
116. Zhu C, etal., Neurochem Res. 2012 Oct;37(10):2099-107. doi: 10.1007/s11064-012-0831-0. Epub 2012 Jun 20.
117. Zhu D, etal., Eye (Lond). 2009 Nov;23(11):2105-11. doi: 10.1038/eye.2009.161. Epub 2009 Jul 3.
Additional References at PubMed
PMID:8226833   PMID:9614124   PMID:11562499   PMID:12632345   PMID:12737624   PMID:12740569   PMID:15020256   PMID:16901919   PMID:17261189   PMID:17943991   PMID:18418629   PMID:19042927  
PMID:19056867   PMID:19188429   PMID:19608741   PMID:20551380   PMID:21750722   PMID:22206666   PMID:22266516   PMID:22906018   PMID:22944728   PMID:23376485   PMID:23533145   PMID:24006456  
PMID:25337213   PMID:25673207   PMID:25890298   PMID:26277390   PMID:26519036   PMID:27214310   PMID:27413044   PMID:27973457   PMID:29210651   PMID:29568944   PMID:30142325   PMID:30180954  
PMID:30230261   PMID:30232174   PMID:30819588   PMID:30864707   PMID:31718448  


Genomics

Comparative Map Data
Serpinf1
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
mRatBN7.21060,250,198 - 60,262,593 (-)NCBImRatBN7.2
mRatBN7.2 Ensembl1060,249,708 - 60,262,646 (-)Ensembl
Rnor_6.01062,241,750 - 62,254,145 (-)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl1062,241,756 - 62,254,287 (-)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.01061,954,919 - 61,969,094 (-)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.41062,713,441 - 62,739,444 (-)NCBIRGSC3.4rn4RGSC3.4
RGSC_v3.11062,727,065 - 62,753,067 (-)NCBI
Celera1059,279,849 - 59,291,539 (-)NCBICelera
Cytogenetic Map10q24NCBI
SERPINF1
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh38.p13 Ensembl171,762,029 - 1,777,565 (+)EnsemblGRCh38hg38GRCh38
GRCh38171,762,060 - 1,777,565 (+)NCBIGRCh38GRCh38hg38GRCh38
GRCh37171,665,354 - 1,680,859 (+)NCBIGRCh37GRCh37hg19GRCh37
Build 36171,612,009 - 1,627,618 (+)NCBINCBI36hg18NCBI36
Build 34171,612,008 - 1,627,618NCBI
Celera171,681,796 - 1,697,412 (+)NCBI
Cytogenetic Map17p13.3NCBI
HuRef171,562,622 - 1,578,251 (+)NCBIHuRef
CHM1_1171,673,331 - 1,688,930 (+)NCBICHM1_1
Serpinf1
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm391175,300,855 - 75,313,449 (-)NCBIGRCm39mm39
GRCm39 Ensembl1175,300,595 - 75,313,527 (-)Ensembl
GRCm381175,410,029 - 75,422,623 (-)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl1175,409,769 - 75,422,701 (-)EnsemblGRCm38mm10GRCm38
MGSCv371175,223,531 - 75,236,125 (-)NCBIGRCm37mm9NCBIm37
MGSCv361175,225,964 - 75,238,707 (-)NCBImm8
Celera1182,918,458 - 82,931,037 (-)NCBICelera
Cytogenetic Map11B5NCBI
Serpinf1
(Chinchilla lanigera - long-tailed chinchilla)
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0 EnsemblNW_0049554811,414,930 - 1,426,241 (-)EnsemblChiLan1.0
ChiLan1.0NW_0049554811,414,930 - 1,426,436 (-)NCBIChiLan1.0ChiLan1.0
SERPINF1
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
PanPan1.1171,638,479 - 1,653,568 (+)NCBIpanpan1.1PanPan1.1panPan2
PanPan1.1 Ensembl171,638,556 - 1,653,568 (+)Ensemblpanpan1.1panPan2
Mhudiblu_PPA_v0171,745,597 - 1,761,399 (+)NCBIMhudiblu_PPA_v0panPan3
SERPINF1
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.1945,891,368 - 45,902,768 (+)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
CanFam3.1 Ensembl945,891,410 - 45,902,765 (+)EnsemblCanFam3.1canFam3CanFam3.1
Dog10K_Boxer_Tasha945,042,116 - 45,052,600 (+)NCBI
ROS_Cfam_1.0946,718,522 - 46,730,219 (+)NCBI
UMICH_Zoey_3.1945,488,488 - 45,499,827 (+)NCBI
UNSW_CanFamBas_1.0945,782,914 - 45,794,244 (+)NCBI
UU_Cfam_GSD_1.0945,837,469 - 45,848,807 (+)NCBI
Serpinf1
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HiC_Itri_2NW_02440560245,008,093 - 45,020,363 (+)NCBI
SpeTri2.0NW_0049365387,885,816 - 7,898,308 (+)NCBISpeTri2.0SpeTri2.0SpeTri2.0
SERPINF1
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 Ensembl1247,943,051 - 47,959,472 (+)EnsemblSscrofa11.1susScr11Sscrofa11.1
Sscrofa11.11247,949,004 - 47,959,471 (+)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
SERPINF1
(Chlorocebus sabaeus - green monkey)
Green Monkey AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.1161,408,453 - 1,424,197 (+)NCBI
Vero_WHO_p1.0NW_02366605920,549,218 - 20,565,247 (-)NCBI
Serpinf1
(Heterocephalus glaber - naked mole-rat)
Naked Mole-rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla 1.0NW_0046247864,487,005 - 4,497,706 (+)NCBI

Position Markers
RH127978  
Rat AssemblyChrPosition (strand)SourceJBrowse
mRatBN7.21060,250,372 - 60,250,833 (+)MAPPERmRatBN7.2
Rnor_6.01062,241,925 - 62,242,385NCBIRnor6.0
Rnor_5.01061,955,094 - 61,955,554UniSTSRnor5.0
RGSC_v3.41062,713,616 - 62,714,076UniSTSRGSC3.4
Celera1059,280,024 - 59,280,484UniSTS
Cytogenetic Map10q24UniSTS


QTLs in Region (mRatBN7.2)
The following QTLs overlap with this region.    Full Report CSV TAB Printer Gviewer
RGD IDSymbolNameLODP ValueTraitSub TraitChrStartStopSpecies
70223Bp57Blood pressure QTL 575arterial blood pressure trait (VT:2000000)systolic blood pressure (CMO:0000004)10180676123Rat
631554Bp133Blood pressure QTL 1330.005arterial blood pressure trait (VT:2000000)systolic blood pressure (CMO:0000004)1074336463851208Rat
2298544Neuinf9Neuroinflammation QTL 94.6nervous system integrity trait (VT:0010566)spinal cord complement component 1, q subcomponent, B chain mRNA level (CMO:0002126)10580199062146030Rat
8662860Vetf10Vascular elastic tissue fragility QTL 10artery integrity trait (VT:0010639)number of ruptures of the internal elastic lamina of the abdominal aorta and iliac arteries (CMO:0002562)10615418273453136Rat
61427Cia16Collagen induced arthritis QTL 163.2joint integrity trait (VT:0010548)joint inflammation composite score (CMO:0000919)10635789696121100Rat
2303118Mamtr7Mammary tumor resistance QTL 70.003mammary gland integrity trait (VT:0010552)mammary tumor growth rate (CMO:0000344)109658275104670812Rat
2301967Cm73Cardiac mass QTL 734.55heart left ventricle mass (VT:0007031)heart left ventricle weight to body weight ratio (CMO:0000530)101448701189062041Rat
631268Cia21Collagen induced arthritis QTL 213.1joint integrity trait (VT:0010548)joint inflammation composite score (CMO:0000919)1014487011104060283Rat
2316949Gluco60Glucose level QTL 603.7blood glucose amount (VT:0000188)blood glucose level (CMO:0000046)1014487011107057807Rat
1354587Kidm21Kidney mass QTL 213.3kidney mass (VT:0002707)right kidney wet weight (CMO:0000082)101502851360430477Rat
631564Apr3Acute phase response QTL 33.9blood interleukin-6 amount (VT:0008595)plasma interleukin-6 level (CMO:0001927)101527595560275955Rat
6893350Bw99Body weight QTL 990.870.16body mass (VT:0001259)body weight (CMO:0000012)11590666560906665Rat
6893352Bw100Body weight QTL 1000.330.6body mass (VT:0001259)body weight (CMO:0000012)11590666560906665Rat
1598852Anxrr19Anxiety related response QTL 195.07body movement coordination trait (VT:0005424)number of rearing movements in an experimental apparatus (CMO:0001752)101816784163167841Rat
2313055Bw96Body weight QTL 963.60.0001body mass (VT:0001259)body weight (CMO:0000012)101960648364606483Rat
2313087Bmd80Bone mineral density QTL 803.20.0001tibia mineral mass (VT:1000283)total volumetric bone mineral density (CMO:0001728)101960648364606483Rat
1554317Bmd4Bone mineral density QTL 49.40.0001lumbar vertebra mineral mass (VT:0010511)volumetric bone mineral density (CMO:0001553)101981604299406971Rat
1581497Esta1Estrogen-induced thymic atrophy QTL 1thymus mass (VT:0004954)thymus wet weight (CMO:0000855)102132980561345413Rat
724556Pur2Proteinuria QTL 25.5urine protein amount (VT:0005160)urine protein level (CMO:0000591)102242750090627625Rat
61354Pia10Pristane induced arthritis QTL 100.01joint integrity trait (VT:0010548)joint inflammation composite score (CMO:0000919)1023444813104060283Rat
631267Cia20Collagen induced arthritis QTL 203.2joint integrity trait (VT:0010548)joint inflammation composite score (CMO:0000919)1023444813104060283Rat
61325Aia5Adjuvant induced arthritis QTL 50.01joint integrity trait (VT:0010548)joint inflammation composite score (CMO:0000919)1023444813104060283Rat
70224Eae3Experimental allergic encephalomyelitis QTL 34.1nervous system integrity trait (VT:0010566)experimental autoimmune encephalomyelitis incidence/prevalence measurement (CMO:0001046)102652195761345413Rat
1298069Bp168Blood pressure QTL 1685.5blood pressure trait (VT:0000183)systolic blood pressure (CMO:0000004)102652195798003205Rat
631542Bp82Blood pressure QTL 826.8arterial blood pressure trait (VT:2000000)systolic blood pressure (CMO:0000004)102652195798952741Rat
2300171Bmd58Bone mineral density QTL 584.90.0001lumbar vertebra mineral mass (VT:0010511)volumetric bone mineral density (CMO:0001553)102694462871944628Rat
10402859Bp381Blood pressure QTL 3810.002arterial blood pressure trait (VT:2000000)mean arterial blood pressure (CMO:0000009)102760646872606468Rat
2292441Bp308Blood pressure QTL 308arterial blood pressure trait (VT:2000000)mean arterial blood pressure (CMO:0000009)102760646872606468Rat
724527Bp148Blood pressure QTL 1480.0001arterial blood pressure trait (VT:2000000)mean arterial blood pressure (CMO:0000009)102845313673453136Rat
1331762Rf40Renal function QTL 403.873kidney blood vessel physiology trait (VT:0100012)absolute change in renal vascular resistance (CMO:0001900)102929950464155584Rat
1331791Cm31Cardiac mass QTL 313.84606heart mass (VT:0007028)heart wet weight (CMO:0000069)1029299504107211142Rat
631557Bp136Blood pressure QTL 1360.003arterial blood pressure trait (VT:2000000)systolic blood pressure (CMO:0000004)103063205375632053Rat
1576311Pia26Pristane induced arthritis QTL 26joint integrity trait (VT:0010548)joint inflammation composite score (CMO:0000919)103122402675632053Rat
1578779Tcas10Tongue tumor susceptibility QTL 103.12tongue integrity trait (VT:0010553)number of squamous cell tumors of the tongue with diameter greater than 3 mm (CMO:0001950)103129743976297439Rat
1576319Cia29Collagen induced arthritis QTL 29joint integrity trait (VT:0010548)joint inflammation composite score (CMO:0000919)103397392178973921Rat
1358897Stresp6Stress response QTL 64.170.022blood norepinephrine amount (VT:0005663)plasma norepinephrine level (CMO:0001010)103539226764155584Rat
61441Btemp1Thermal response to stress QTL 14body temperature trait (VT:0005535)core body temperature (CMO:0001036)103539245763642539Rat
2317042Aia20Adjuvant induced arthritis QTL 203.38joint integrity trait (VT:0010548)right rear ankle joint diameter (CMO:0002150)103756507982565079Rat
2317043Aia7Adjuvant induced arthritis QTL 73.82joint integrity trait (VT:0010548)left rear ankle joint diameter (CMO:0002149)103756507982565079Rat
1576308Schws1Schwannoma susceptibility QTL 10.0041nervous system integrity trait (VT:0010566)percentage of study population developing trigeminal nerve neurilemmomas during a period of time (CMO:0002017)1040035094102359817Rat
631269Cia22Collagen induced arthritis QTL 228.9joint integrity trait (VT:0010548)joint inflammation composite score (CMO:0000919)1040035094104060283Rat
631270Cia23Collagen induced arthritis QTL 233.9joint integrity trait (VT:0010548)joint inflammation composite score (CMO:0000919)1040035094104060283Rat
631552Vetf2Vascular elastic tissue fragility QTL 24.50.0002aorta elastic tissue integrity trait (VT:0010556)artery internal elastic lamina non-tumorous lesion count (CMO:0001913)104114263386142633Rat
61463Bp12Blood pressure QTL 126.30.0001arterial blood pressure trait (VT:2000000)systolic blood pressure (CMO:0000004)104133325886333258Rat
8552805Bw145Body weight QTL 1452.2body mass (VT:0001259)change in body weight to body weight ratio (CMO:0002216)104194452678307017Rat
1298078Stresp5Stress response QTL 52.990.00025blood corticosterone amount (VT:0005345)plasma corticosterone level (CMO:0001173)1042045676104670812Rat
70188BpQTLcluster1Blood pressure QTL cluster 14.864arterial blood pressure trait (VT:2000000)diastolic blood pressure (CMO:0000005)14232313287323132Rat
70188BpQTLcluster1Blood pressure QTL cluster 14.864arterial blood pressure trait (VT:2000000)systolic blood pressure (CMO:0000004)14232313287323132Rat
70188BpQTLcluster1Blood pressure QTL cluster 14.864arterial blood pressure trait (VT:2000000)mean arterial blood pressure (CMO:0000009)14232313287323132Rat
70188BpQTLcluster1Blood pressure QTL cluster 14.864arterial blood pressure trait (VT:2000000)pulse pressure (CMO:0000292)14232313287323132Rat
70198BpQTLcluster9Blood pressure QTL cluster 92.94arterial blood pressure trait (VT:2000000)mean arterial blood pressure (CMO:0000009)104232313287323132Rat
6893342Cm78Cardiac mass QTL 780.10.88heart mass (VT:0007028)heart weight to body weight ratio (CMO:0000074)104287676679813922Rat
9589030Epfw9Epididymal fat weight QTL 919.240.001epididymal fat pad mass (VT:0010421)epididymal fat pad weight to body weight ratio (CMO:0000658)104444169989441699Rat
7411614Foco18Food consumption QTL 180.001eating behavior trait (VT:0001431)feed conversion ratio (CMO:0001312)104444169989441699Rat
8694173Bw149Body weight QTL 1494.380.001body mass (VT:0001259)body weight gain (CMO:0000420)104444169989441699Rat
2300218Hpcl2Hepatic cholesterol level QTL 2liver cholesterol amount (VT:0010498)liver cholesterol level (CMO:0001597)104502965095600334Rat
631547Bp87Blood pressure QTL 874.5arterial blood pressure trait (VT:2000000)systolic blood pressure (CMO:0000004)104736947092369470Rat
2293705Bmd25Bone mineral density QTL 257.10.0001femur mineral mass (VT:0010011)cortical volumetric bone mineral density (CMO:0001730)104944455181709989Rat
7207811Bmd90Bone mineral density QTL 905.2femur size trait (VT:1000369)femoral neck cross-sectional area (CMO:0001697)104944455181709989Rat
2293652Bmd22Bone mineral density QTL 224.90.0001femur mineral mass (VT:0010011)total volumetric bone mineral density (CMO:0001728)104944455181709989Rat
2293669Bmd33Bone mineral density QTL 334.50.0001femur strength trait (VT:0010010)femoral neck polar moment of inertia (CMO:0001670)104944455181709989Rat
2293679Bmd30Bone mineral density QTL 303.50.0001femur mineral mass (VT:0010011)total volumetric bone mineral density (CMO:0001728)104944455181709989Rat
1549846Scl47Serum cholesterol level QTL 473.6blood cholesterol amount (VT:0000180)serum total cholesterol level (CMO:0000363)105057470795574707Rat
70364Bp72Blood pressure QTL 72arterial blood pressure trait (VT:2000000)mean arterial blood pressure (CMO:0000009)105112110096121100Rat
61387Bp1Blood pressure QTL 15.1arterial blood pressure trait (VT:2000000)systolic blood pressure (CMO:0000004)1051770177107211142Rat
61387Bp1Blood pressure QTL 15.1arterial blood pressure trait (VT:2000000)diastolic blood pressure (CMO:0000005)1051770177107211142Rat
1359017Hrtrt21Heart rate QTL 212.4heart pumping trait (VT:2000009)heart rate (CMO:0000002)105177294096772940Rat
631530Tls3T-lymphoma susceptibility QTL 300.0001thymus integrity trait (VT:0010555)percentage of study population developing T-cell lymphomas during a period of time (CMO:0001911)105177461295600334Rat
631535Cm51Cardiac mass QTL 513heart mass (VT:0007028)calculated heart weight (CMO:0000073)105178628291669536Rat
2306787Ean3Experimental allergic neuritis QTL 33.1nervous system integrity trait (VT:0010566)body weight loss (CMO:0001399)105379738566979128Rat
70171Cari1Carrageenan-induced inflammation QTL 14.90.0005hypodermis integrity trait (VT:0010550)inflammatory exudate volume (CMO:0001429)1053797385107211142Rat
70164Bw21Body weight QTL 214.360.00005body mass (VT:0001259)body weight (CMO:0000012)105379749498952626Rat
1354608Cm33Cardiac mass QTL 332.8heart left ventricle mass (VT:0007031)heart left ventricle wet weight (CMO:0000071)105480929299809292Rat
2298495Eae23Experimental allergic encephalomyelitis QTL 2316.93nervous system integrity trait (VT:0010566)experimental autoimmune encephalomyelitis duration (CMO:0001424)105527369660677262Rat
2312662Slep8Serum leptin concentration QTL 80.05blood leptin amount (VT:0005667)serum leptin level (CMO:0000780)1057134272102134272Rat
2312668Scl65Serum cholesterol level QTL 650.001blood cholesterol amount (VT:0000180)serum total cholesterol level (CMO:0000363)1057134272102134272Rat
2312672Insul15Insulin level QTL 150.01blood insulin amount (VT:0001560)serum insulin level (CMO:0000358)1057134272102134272Rat
1549831Bss6Bone structure and strength QTL 64lumbar vertebra strength trait (VT:0010574)vertebra ultimate force (CMO:0001678)1057576521102576521Rat
2293698Bss43Bone structure and strength QTL 435.330.0001lumbar vertebra size trait (VT:0010518)lumbar vertebra cross-sectional area (CMO:0001689)1059209888104209888Rat

miRNA Target Status

Predicted Target Of
Summary Value
Count of predictions:68
Count of miRNA genes:62
Interacting mature miRNAs:67
Transcripts:ENSRNOT00000004313
Prediction methods:Miranda, Rnahybrid, Targetscan
Result types:miRGate_prediction

The detailed report is available here: Full Report CSV TAB Printer

miRNA Target Status data imported from miRGate (http://mirgate.bioinfo.cnio.es/).
For more information about miRGate, see PMID:25858286 or access the full paper here.


Expression


RNA-SEQ Expression
High: > 1000 TPM value   Medium: Between 11 and 1000 TPM
Low: Between 0.5 and 10 TPM   Below Cutoff: < 0.5 TPM

alimentary part of gastrointestinal system circulatory system endocrine system exocrine system hemolymphoid system hepatobiliary system integumental system musculoskeletal system nervous system renal system reproductive system respiratory system appendage
High 6 6 6
Medium 3 37 45 35 6 35 8 11 54 35 33 11 8
Low 6 6 13 18 8
Below cutoff 2

Sequence


Reference Sequences
RefSeq Acc Id: ENSRNOT00000004313   ⟹   ENSRNOP00000004313
RefSeq Status:
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.2 Ensembl1060,249,708 - 60,262,646 (-)Ensembl
Rnor_6.0 Ensembl1062,241,756 - 62,254,287 (-)Ensembl
RefSeq Acc Id: ENSRNOT00000112278   ⟹   ENSRNOP00000091165
RefSeq Status:
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.2 Ensembl1060,254,605 - 60,262,646 (-)Ensembl
RefSeq Acc Id: NM_177927   ⟹   NP_808788
RefSeq Status: PROVISIONAL
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.21060,250,198 - 60,262,593 (-)NCBI
Rnor_6.01062,241,750 - 62,254,145 (-)NCBI
Rnor_5.01061,954,919 - 61,969,094 (-)NCBI
RGSC_v3.41062,713,441 - 62,739,444 (-)RGD
Celera1059,279,849 - 59,291,539 (-)RGD
Sequence:
Protein Sequences
Protein RefSeqs NP_808788 (Get FASTA)   NCBI Sequence Viewer  
GenBank Protein AAH78686 (Get FASTA)   NCBI Sequence Viewer  
  AAO60104 (Get FASTA)   NCBI Sequence Viewer  
  EDM05207 (Get FASTA)   NCBI Sequence Viewer  
  EDM05208 (Get FASTA)   NCBI Sequence Viewer  
  EDM05209 (Get FASTA)   NCBI Sequence Viewer  
Reference Sequences
RefSeq Acc Id: NP_808788   ⟸   NM_177927
- Peptide Label: precursor
- UniProtKB: Q80ZA3 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: ENSRNOP00000004313   ⟸   ENSRNOT00000004313
RefSeq Acc Id: ENSRNOP00000091165   ⟸   ENSRNOT00000112278
Protein Domains
SERPIN

Transcriptome

eQTL   View at Phenogen
WGCNA   View at Phenogen
Tissue/Strain Expression   View at Phenogen

Promoters
RGD ID:13697424
Promoter ID:EPDNEW_R7947
Type:initiation region
Name:Serpinf1_1
Description:serpin family F member 1
SO ACC ID:SO:0000170
Source:EPDNEW (Eukaryotic Promoter Database, http://epd.vital-it.ch/)
Experiment Methods:Single-end sequencing.
Position:
Rat AssemblyChrPosition (strand)Source
Rnor_6.01062,254,145 - 62,254,205EPDNEW

Strain Variation

Strain Sequence Variants (Rnor 6.0)
ACI/EurMcwi (2019)
Visual CSV TAB Printer
Sequenced By: MCW
Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: MCW
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
ACI/EurMcwi (MCW)
Visual CSV TAB Printer
Sequenced By: Medical College of Wisconsin (Dr. Howard Jacob)
Platform: Illumina HiSeq 2000
Secondary Analysis: BWA v0.7.7 and GATK v3.2-2
Breeder: Medical College of Wisconsin
Description: Provided by the Medical College of Wisconsin (Dr. Howard Jacob)
ACI/EurMcwi (RGD)
Visual CSV TAB Printer
Platform: Illumina HiSeq 2000
Secondary Analysis: BWA mem 0.7.15, GATK v.3.6-0
Description: Sequences from Atanur et al and Hermsen et al realigned to the Rnor 6.0 assembly and reanalyzed by RGD
ACI/N (2020)
Visual CSV TAB Printer
Sequenced By: MCW
Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: NIH
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
ACI/N (MCW)
Visual CSV TAB Printer
Sequenced By: Royal Netherland Academy of Arts and Sciences (Dr. Edwin Cuppen)
Max Delbruck Center for Molecular Medicine (Dr. Norbert Huebner)
Platform: SOLiD 4 and 5500
Secondary Analysis: liftOver (Batch Coordinate Conversion)--genome.ucsc.edu
Breeder: National Institutes of Health
Description: Founder strain for the heterogeneous stock (HS) rat population; SNPs from the RGSC 3.4 assembly were "lifted over" from RGSC 3.4 to Rnor 5.0 and from Rnor 5.0 to Rnor 6.0; Provided by Medical College of Wisconsin
BBDP/Wor (RGD)
Visual CSV TAB Printer
Platform: Illumina HiSeq 2000
Secondary Analysis: BWA mem 0.7.15, GATK v.3.6-0
Description: Sequences from Atanur et al and Hermsen et al realigned to the Rnor 6.0 assembly and reanalyzed by RGD
BN-Lx/CubMcwi (2019)
Visual CSV TAB Printer
Sequenced By: MCW
Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: MCW
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
BN/NHsdMcwi (2019)
Visual CSV TAB Printer
Sequenced By: MCW
Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: MCW
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
BN/NHsdMcwi (2020)
Visual CSV TAB Printer
Sequenced By: MCW
Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: MCW
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
BN/SsN (2020)
Visual CSV TAB Printer
Sequenced By: MCW
Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: NIH
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
BN/SsN (MCW)
Visual CSV TAB Printer
Sequenced By: Royal Netherland Academy of Arts and Sciences (Dr. Edwin Cuppen)
Max Delbruck Center for Molecular Medicine (Dr. Norbert Huebner)
Platform: SOLiD 4 and 5500
Secondary Analysis: liftOver (Batch Coordinate Conversion)--genome.ucsc.edu
Breeder: National Institutes of Health
Description: Founder strain for the heterogeneous stock (HS) rat population; SNPs from the RGSC 3.4 assembly were "lifted over" from RGSC 3.4 to Rnor 5.0 and from Rnor 5.0 to Rnor 6.0; Provided by Medical College of Wisconsin
BUF/N (2020)
Visual CSV TAB Printer
Sequenced By: MCW
Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: NIH
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
BXH2/CubMcwi (2020)
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Sequenced By: MCW
Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: MCW
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
BXH3/CubMcwi (2020)
Visual CSV TAB Printer
Sequenced By: MCW
Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: MCW
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
Buf/N (MCW)
Visual CSV TAB Printer
Sequenced By: Royal Netherland Academy of Arts and Sciences (Dr. Edwin Cuppen)
Max Delbruck Center for Molecular Medicine (Dr. Norbert Huebner)
Platform: SOLiD 4 and 5500
Secondary Analysis: liftOver (Batch Coordinate Conversion)--genome.ucsc.edu
Breeder: National Institutes of Health
Description: Founder strain for the heterogeneous stock (HS) rat population; SNPs from the RGSC 3.4 assembly were "lifted over" from RGSC 3.4 to Rnor 5.0 and from Rnor 5.0 to Rnor 6.0; Provided by Medical College of Wisconsin
COP/CrCrl (MCW & UW)
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Sequenced By: Medical College of Wisconsin (Dr. Howard Jacob)
University of Wisconsin (Dr. James Shull)
Platform: Illumina HiSeq 2000
Secondary Analysis: BWA v0.7.7 and GATK v3.2-2
Breeder: Charles River Laboratories
Description: Provided by the Medical College of Wisconsin (Dr. Howard Jacob) and UW Madison (Dr. James Shull)
DA/OlaHsd (2019)
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Sequenced By: MCW
Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: Envigo
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
F344/DuCrl (2019)
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Sequenced By: MCW
Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: Charles River
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
F344/N (2020)
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Sequenced By: MCW
Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: NIH
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
F344/NCrl (2019)
Visual CSV TAB Printer
Sequenced By: MCW
Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: Charles River
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
F344/NCrl (RGD)
Visual CSV TAB Printer
Platform: Illumina HiSeq 2000
Secondary Analysis: BWA mem 0.7.15, GATK v.3.6-0
Description: Sequences from Atanur et al and Hermsen et al realigned to the Rnor 6.0 assembly and reanalyzed by RGD
F344/NRrrc (MCW)
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Sequenced By: Royal Netherland Academy of Arts and Sciences (Dr. Edwin Cuppen)
Max Delbruck Center for Molecular Medicine (Dr. Norbert Huebner)
Platform: SOLiD 4 and 5500
Secondary Analysis: liftOver (Batch Coordinate Conversion)--genome.ucsc.edu
Breeder: National Institutes of Health
Description: Founder strain for the heterogeneous stock (HS) rat population; SNPs from the RGSC 3.4 assembly were "lifted over" from RGSC 3.4 to Rnor 5.0 and from Rnor 5.0 to Rnor 6.0; Provided by Medical College of Wisconsin
F344/Stm (2019)
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Sequenced By: MCW
Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: Japan
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
FHH/EurMcwi (2019)
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Sequenced By: MCW
Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: MCW
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
FHH/EurMcwi (MCW)
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Sequenced By: Medical College of Wisconsin (Dr. Howard Jacob)
Platform: Illumina HiSeq 2000
Secondary Analysis: BWA v0.7.7 and GATK v3.2-2
Breeder: Medical College of Wisconsin
Description: Provided by the Medical College of Wisconsin (Dr. Howard Jacob)
FHH/EurMcwi (RGD)
Visual CSV TAB Printer
Platform: Illumina HiSeq 2000
Secondary Analysis: BWA mem 0.7.15, GATK v.3.6-0
Description: Sequences from Atanur et al and Hermsen et al realigned to the Rnor 6.0 assembly and reanalyzed by RGD
FHL/EurMcwi (MCW)
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Sequenced By: Medical College of Wisconsin (Dr. Howard Jacob)
Platform: Illumina HiSeq 2000
Secondary Analysis: BWA v0.7.7 and GATK v3.2-2
Breeder: Medical College of Wisconsin
Description: Provided by the Medical College of Wisconsin (Dr. Howard Jacob)
FHL/EurMcwi (RGD)
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Platform: Illumina HiSeq 2000
Secondary Analysis: BWA mem 0.7.15, GATK v.3.6-0
Description: Sequences from Atanur et al and Hermsen et al realigned to the Rnor 6.0 assembly and reanalyzed by RGD
FXLE16/Stm (2020)
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Sequenced By: MCW
Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: Japan
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
FXLE18/Stm (2020)
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Sequenced By: MCW
Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: Japan
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
GH/OmrMcwi (MCW)
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Sequenced By: Medical College of Wisconsin (Dr. Howard Jacob)
Platform: Illumina HiSeq 2000
Secondary Analysis: BWA v0.7.7 and GATK v3.2-2
Breeder: Medical College of Wisconsin
Description: Provided by the Medical College of Wisconsin (Dr. Howard Jacob)
GK/FarMcwi (2019)
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Sequenced By: MCW
Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: MCW
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
GK/Ox (RGD)
Visual CSV TAB Printer
Platform: Illumina HiSeq 2000
Secondary Analysis: BWA mem 0.7.15, GATK v.3.6-0
Description: Sequences from Atanur et al and Hermsen et al realigned to the Rnor 6.0 assembly and reanalyzed by RGD
HXB10/IpcvMcwi (2019)
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Sequenced By: MCW
Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: MCW
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
HXB2/IpcvMcwi (2019)
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Sequenced By: MCW
Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: MCW
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
HXB20/IpcvMcwi (2020)
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Sequenced By: MCW
Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: MCW
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
HXB31/IpcvMcwi (2019)
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Sequenced By: MCW
Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: MCW
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
HXB4/IpcvMcwi (2020)
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Sequenced By: MCW
Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: MCW
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
LE/Stm (2019)
Visual CSV TAB Printer
Sequenced By: MCW
Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: Japan
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
LE/Stm (RGD)
Visual CSV TAB Printer
Platform: Illumina HiSeq 2000
Secondary Analysis: BWA mem 0.7.15, GATK v.3.6-0
Description: Sequences from Atanur et al and Hermsen et al realigned to the Rnor 6.0 assembly and reanalyzed by RGD
LEW/Crl (2019)
Visual CSV TAB Printer
Sequenced By: MCW
Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: Charles River
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
LEW/Crl (RGD)
Visual CSV TAB Printer
Platform: Illumina HiSeq 2000
Secondary Analysis: BWA mem 0.7.15, GATK v.3.6-0
Description: Sequences from Atanur et al and Hermsen et al realigned to the Rnor 6.0 assembly and reanalyzed by RGD
LEW/NCrlBR (RGD)
Visual CSV TAB Printer
Platform: Illumina HiSeq 2000
Secondary Analysis: BWA mem 0.7.15, GATK v.3.6-0
Description: Sequences from Atanur et al and Hermsen et al realigned to the Rnor 6.0 assembly and reanalyzed by RGD
LEXF10A/StmMcwi (2020)
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Sequenced By: MCW
Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: MCW
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
LEXF11/Stm (2020)
Visual CSV TAB Printer
Sequenced By: MCW
Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: Japan
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
LEXF1A/Stm (2019)
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Sequenced By: MCW
Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: Japan
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
LEXF1C/Stm (2019)
Visual CSV TAB Printer
Sequenced By: MCW
Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: Japan
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
LEXF2B/Stm (2019)
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Sequenced By: MCW
Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: Japan
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
LEXF3/Stm (2020)
Visual CSV TAB Printer
Sequenced By: MCW
Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: Japan
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
LEXF4/Stm (2020)
Visual CSV TAB Printer
Sequenced By: MCW
Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: Japan
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
LH/MavRrrc (RGD)
Visual CSV TAB Printer
Platform: Illumina HiSeq 2000
Secondary Analysis: BWA mem 0.7.15, GATK v.3.6-0
Description: Sequences from Atanur et al and Hermsen et al realigned to the Rnor 6.0 assembly and reanalyzed by RGD
LH/MavRrrcAek (2020)
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Sequenced By: MCW
Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: Kwitek
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
LL/MavRrrc (RGD)
Visual CSV TAB Printer
Platform: Illumina HiSeq 2000
Secondary Analysis: BWA mem 0.7.15, GATK v.3.6-0
Description: Sequences from Atanur et al and Hermsen et al realigned to the Rnor 6.0 assembly and reanalyzed by RGD
LL/MavRrrcAek (2020)
Visual CSV TAB Printer
Sequenced By: MCW
Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: Kwitek
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
LN/MavRrrc (RGD)
Visual CSV TAB Printer
Platform: Illumina HiSeq 2000
Secondary Analysis: BWA mem 0.7.15, GATK v.3.6-0
Description: Sequences from Atanur et al and Hermsen et al realigned to the Rnor 6.0 assembly and reanalyzed by RGD
LN/MavRrrcAek (2020)
Visual CSV TAB Printer
Sequenced By: MCW
Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: Kwitek
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
M520/N (2020)
Visual CSV TAB Printer
Sequenced By: MCW
Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: NIH
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
M520/N (MCW)
Visual CSV TAB Printer
Sequenced By: Royal Netherland Academy of Arts and Sciences (Dr. Edwin Cuppen)
Max Delbruck Center for Molecular Medicine (Dr. Norbert Huebner)
Platform: SOLiD 4 and 5500
Secondary Analysis: liftOver (Batch Coordinate Conversion)--genome.ucsc.edu
Breeder: National Institutes of Health
Description: Founder strain for the heterogeneous stock (HS) rat population; SNPs from the RGSC 3.4 assembly were "lifted over" from RGSC 3.4 to Rnor 5.0 and from Rnor 5.0 to Rnor 6.0; Provided by Medical College of Wisconsin
M520/NRrrcMcwi (2019)
Visual CSV TAB Printer
Sequenced By: MCW
Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: MCW
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
MHS/Gib (RGD)
Visual CSV TAB Printer
Platform: Illumina HiSeq 2000
Secondary Analysis: BWA mem 0.7.15, GATK v.3.6-0
Description: Sequences from Atanur et al and Hermsen et al realigned to the Rnor 6.0 assembly and reanalyzed by RGD
MNS/Gib (RGD)
Visual CSV TAB Printer
Platform: Illumina HiSeq 2000
Secondary Analysis: BWA mem 0.7.15, GATK v.3.6-0
Description: Sequences from Atanur et al and Hermsen et al realigned to the Rnor 6.0 assembly and reanalyzed by RGD
MR/N (2020)
Visual CSV TAB Printer
Sequenced By: MCW
Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: NIH
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
MR/N (MCW)
Visual CSV TAB Printer
Sequenced By: Royal Netherland Academy of Arts and Sciences (Dr. Edwin Cuppen)
Max Delbruck Center for Molecular Medicine (Dr. Norbert Huebner)
Platform: SOLiD 4 and 5500
Secondary Analysis: liftOver (Batch Coordinate Conversion)--genome.ucsc.edu
Breeder: National Institutes of Health
Description: Founder strain for the heterogeneous stock (HS) rat population; SNPs from the RGSC 3.4 assembly were "lifted over" from RGSC 3.4 to Rnor 5.0 and from Rnor 5.0 to Rnor 6.0; Provided by Medical College of Wisconsin
MWF/Hsd (2019)
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Sequenced By: MCW
Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: MCW
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
PVG/Seac (2019)
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Sequenced By: MCW
Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: Japan
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
SBH/Ygl (MCW)
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Sequenced By: Medical College of Wisconsin (Dr. Howard Jacob)
Platform: Illumina HiSeq 2000
Secondary Analysis: BWA v0.7.7 and GATK v3.2-2
Breeder: Medical College of Wisconsin
Description: SBH/Ygl sequenced by MCW
SBH/Ygl (RGD)
Visual CSV TAB Printer
Platform: Illumina HiSeq 2000
Secondary Analysis: BWA mem 0.7.15, GATK v.3.6-0
Description: Sequences from Atanur et al and Hermsen et al realigned to the Rnor 6.0 assembly and reanalyzed by RGD
SBN/Ygl (MCW)
Visual CSV TAB Printer
Sequenced By: Medical College of Wisconsin (Dr. Howard Jacob)
Platform: Illumina HiSeq 2000
Secondary Analysis: BWA v0.7.7 and GATK v3.2-2
Breeder: Medical College of Wisconsin
Description: SBN/Ygl sequenced by MCW
SBN/Ygl (RGD)
Visual CSV TAB Printer
Platform: Illumina HiSeq 2000
Secondary Analysis: BWA mem 0.7.15, GATK v.3.6-0
Description: Sequences from Atanur et al and Hermsen et al realigned to the Rnor 6.0 assembly and reanalyzed by RGD
SHR/NHsd (RGD)
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Platform: Illumina HiSeq 2000
Secondary Analysis: BWA mem 0.7.15, GATK v.3.6-0
Description: Sequences from Atanur et al and Hermsen et al realigned to the Rnor 6.0 assembly and reanalyzed by RGD
SHR/OlalpcvMcwi (2019)
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Sequenced By: MCW
Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: MCW
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
SHRSP/A3NCrl (2019)
Visual CSV TAB Printer
Sequenced By: MCW
Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: Charles River
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
SHRSP/Gcrc (RGD)
Visual CSV TAB Printer
Platform: Illumina HiSeq 2000
Secondary Analysis: BWA mem 0.7.15, GATK v.3.6-0
Description: Sequences from Atanur et al and Hermsen et al realigned to the Rnor 6.0 assembly and reanalyzed by RGD
SR/JrHsd (2020)
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Sequenced By: MCW
Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: Envigo
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
SR/JrHsd (MCW)
Visual CSV TAB Printer
Sequenced By: Medical College of Wisconsin (Dr. Howard Jacob)
Platform: Illumina HiSeq 2000
Secondary Analysis: BWA v0.7.7 and GATK v3.2-2
Breeder: Harlan Laboratories
Description: Provided by the Medical College of Wisconsin (Dr. Howard Jacob)
SR/JrHsd (RGD)
Visual CSV TAB Printer
Platform: Illumina HiSeq 2000
Secondary Analysis: BWA mem 0.7.15, GATK v.3.6-0
Description: Sequences from Atanur et al and Hermsen et al realigned to the Rnor 6.0 assembly and reanalyzed by RGD
SS/Jr (RGD)
Visual CSV TAB Printer
Platform: Illumina HiSeq 2000
Secondary Analysis: BWA mem 0.7.15, GATK v.3.6-0
Description: Sequences from Atanur et al and Hermsen et al realigned to the Rnor 6.0 assembly and reanalyzed by RGD
SS/JrHsdMcwi (2019)
Visual CSV TAB Printer
Sequenced By: MCW
Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: MCW
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
SS/JrHsdMcwi (MCW)
Visual CSV TAB Printer
Sequenced By: Medical College of Wisconsin (Dr. Howard Jacob)
Platform: Illumina HiSeq 2000
Secondary Analysis: BWA v0.7.7 and GATK v3.2-2
Breeder: Medical College of Wisconsin
Description: Provided by the Medical College of Wisconsin (Dr. Howard Jacob)
SS/JrHsdMcwi (RGD)
Visual CSV TAB Printer
Platform: Illumina HiSeq 2000
Secondary Analysis: BWA mem 0.7.15, GATK v.3.6-0
Description: Sequences from Atanur et al and Hermsen et al realigned to the Rnor 6.0 assembly and reanalyzed by RGD
WAG/Rij (RGD)
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Platform: Illumina HiSeq 2000
Secondary Analysis: BWA mem 0.7.15, GATK v.3.6-0
Description: Sequences from Atanur et al and Hermsen et al realigned to the Rnor 6.0 assembly and reanalyzed by RGD
WAG/RijCrl (2020)
Visual CSV TAB Printer
Sequenced By: MCW
Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: Charles River
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
WKY/Gcrc (RGD)
Visual CSV TAB Printer
Platform: Illumina HiSeq 2000
Secondary Analysis: BWA mem 0.7.15, GATK v.3.6-0
Description: Sequences from Atanur et al and Hermsen et al realigned to the Rnor 6.0 assembly and reanalyzed by RGD
WKY/N (2020)
Visual CSV TAB Printer
Sequenced By: MCW
Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: NIH
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
WKY/N (MCW)
Visual CSV TAB Printer
Sequenced By: Royal Netherland Academy of Arts and Sciences (Dr. Edwin Cuppen)
Max Delbruck Center for Molecular Medicine (Dr. Norbert Huebner)
Platform: SOLiD 4 and 5500
Secondary Analysis: liftOver (Batch Coordinate Conversion)--genome.ucsc.edu
Breeder: National Institutes of Health
Description: Founder strain for the heterogeneous stock (HS) rat population; SNPs from the RGSC 3.4 assembly were "lifted over" from RGSC 3.4 to Rnor 5.0 and from Rnor 5.0 to Rnor 6.0; Provided by Medical College of Wisconsin
WKY/NCrl (2019)
Visual CSV TAB Printer
Sequenced By: MCW
Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: Charles River
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
WKY/NCrl (RGD)
Visual CSV TAB Printer
Platform: Illumina HiSeq 2000
Secondary Analysis: BWA mem 0.7.15, GATK v.3.6-0
Description: Sequences from Atanur et al and Hermsen et al realigned to the Rnor 6.0 assembly and reanalyzed by RGD
WKY/NHsd (RGD)
Visual CSV TAB Printer
Platform: Illumina HiSeq 2000
Secondary Analysis: BWA mem 0.7.15, GATK v.3.6-0
Description: Sequences from Atanur et al and Hermsen et al realigned to the Rnor 6.0 assembly and reanalyzed by RGD
WN/N (2020)
Visual CSV TAB Printer
Sequenced By: MCW
Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: NIH
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
WN/N (MCW)
Visual CSV TAB Printer
Sequenced By: Royal Netherland Academy of Arts and Sciences (Dr. Edwin Cuppen)
Max Delbruck Center for Molecular Medicine (Dr. Norbert Huebner)
Platform: SOLiD 4 and 5500
Secondary Analysis: liftOver (Batch Coordinate Conversion)--genome.ucsc.edu
Breeder: National Institutes of Health
Description: Founder strain for the heterogeneous stock (HS) rat population; SNPs from the RGSC 3.4 assembly were "lifted over" from RGSC 3.4 to Rnor 5.0 and from Rnor 5.0 to Rnor 6.0; Provided by Medical College of Wisconsin

Additional Information

Database Acc Id Source(s)
AGR Gene RGD:631369 AgrOrtholog
Ensembl Genes ENSRNOG00000003172 Ensembl, ENTREZGENE, UniProtKB/TrEMBL
Ensembl Protein ENSRNOP00000004313 ENTREZGENE, UniProtKB/TrEMBL
Ensembl Transcript ENSRNOT00000004313 ENTREZGENE, UniProtKB/TrEMBL
Gene3D-CATH 2.30.39.10 UniProtKB/TrEMBL
  3.30.497.10 UniProtKB/TrEMBL
IMAGE_CLONE IMAGE:7110230 IMAGE-MGC_LOAD
InterPro PEDF UniProtKB/TrEMBL
  Protease_inhib_I4_serpin UniProtKB/TrEMBL
  Protease_inhib_I4_serpin_CS UniProtKB/TrEMBL
  Sepin_dom UniProtKB/TrEMBL
  Serpin_sf UniProtKB/TrEMBL
  Serpin_sf_1 UniProtKB/TrEMBL
  Serpin_sf_2 UniProtKB/TrEMBL
KEGG Report rno:287526 UniProtKB/TrEMBL
MGC_CLONE MGC:93051 IMAGE-MGC_LOAD
NCBI Gene 287526 ENTREZGENE
PANTHER Prot_inh_serpin UniProtKB/TrEMBL
Pfam Serpin UniProtKB/TrEMBL
PhenoGen Serpinf1 PhenoGen
PROSITE SERPIN UniProtKB/TrEMBL
SMART SERPIN UniProtKB/TrEMBL
Superfamily-SCOP Prot_inh_serpin UniProtKB/TrEMBL
UniProt Q80ZA3 ENTREZGENE, UniProtKB/TrEMBL
UniProt Secondary F1LSW0 UniProtKB/TrEMBL


Nomenclature History
Date Current Symbol Current Name Previous Symbol Previous Name Description Reference Status
2016-04-20 Serpinf1  serpin family F member 1  Serpinf1  sserpin family F member 1  Nomenclature updated to reflect human and mouse nomenclature 1299863 APPROVED
2016-04-13 Serpinf1  sserpin family F member 1  Serpinf1  serpin peptidase inhibitor, clade F (alpha-2 antiplasmin, pigment epithelium derived factor), member 1  Nomenclature updated to reflect human and mouse nomenclature 1299863 APPROVED
2011-01-19 Serpinf1  serpin peptidase inhibitor, clade F (alpha-2 antiplasmin, pigment epithelium derived factor), member 1  Serpinf1  serine (or cysteine) peptidase inhibitor, clade F, member 1  Nomenclature updated to reflect human and mouse nomenclature 1299863 APPROVED
2006-03-30 Serpinf1  serine (or cysteine) peptidase inhibitor, clade F, member 1    serine (or cysteine) proteinase inhibitor, clade F), member 1  Name updated 1299863 APPROVED
2004-02-11 Serpinf1  serine (or cysteine) proteinase inhibitor, clade F), member 1  Dmrs91  alpha-2 antiplasmin  Symbol and Name updated to reflect Human and Mouse nomenclature 625702 APPROVED