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Gene: Pdlim4 (PDZ and LIM domain 4) Rattus norvegicus
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Symbol: Pdlim4
Name: PDZ and LIM domain 4
Description: Exhibits alpha-actinin binding activity. Involved in actin cytoskeleton organization; excitatory chemical synaptic transmission; and positive regulation of stress fiber assembly. Localizes to several cellular components, including the dendritic spine; endosome; and stress fiber. Human ortholog(s) of this gene implicated in osteoporosis. Orthologous to human PDLIM4 (PDZ and LIM domain 4); INTERACTS WITH 1,3,5-trinitro-1,3,5-triazinane; bisphenol A; endosulfan.
Type: protein-coding
RefSeq Status: PROVISIONAL
Also known as: H-Rev18; LIM protein RIL; PDZ and LIM domain protein 4; reversion induced LIM; reversion induced LIM gene; reversion-induced LIM protein; Ril; RIT-18
Orthologs:
Homo sapiens (human) : PDLIM4 (PDZ and LIM domain 4)  HGNC  Alliance
Mus musculus (house mouse) : Pdlim4 (PDZ and LIM domain 4)  MGI  Alliance
Chinchilla lanigera (long-tailed chinchilla) : Pdlim4 (PDZ and LIM domain 4)
Pan paniscus (bonobo/pygmy chimpanzee) : PDLIM4 (PDZ and LIM domain 4)
Canis lupus familiaris (dog) : PDLIM4 (PDZ and LIM domain 4)
Ictidomys tridecemlineatus (thirteen-lined ground squirrel) : Pdlim4 (PDZ and LIM domain 4)
Sus scrofa (pig) : PDLIM4 (PDZ and LIM domain 4)
more info ...
Latest Assembly: Rnor_6.0 - RGSC Genome Assembly v6.0
Position:
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Rnor_6.01039,390,578 - 39,405,322 (-)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_5.01039,171,365 - 39,185,480 (-)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
Celera1037,540,725 - 37,554,961 (-)NCBICelera
Cytogenetic Map10q22NCBI
JBrowse: View Region in Genome Browser (JBrowse)
Model


Disease Annotations
Gene-Chemical Interaction Annotations
Gene Ontology Annotations
References - curated
References - uncurated
RGD Disease Portals

Genomics

Comparative Map Data
QTLs in Region (Rnor_6.0)
miRNA Target Status

Sequence

Nucleotide Sequences
Protein Sequences
Transcriptome
Promoters

Strain Variation

Strain Sequence Variants (Rnor 5.0)

Additional Information

External Database Links
Nomenclature History
RGD Curation Notes
 
More on Pdlim4
Alliance Gene
NCBI Gene
Ensembl Gene
JBrowse: rn5 rn6
NCBI Genome Data Viewer

RGD Object Information
RGD ID: 3575
Created: 2000-05-25
Species: Rattus norvegicus
Last Modified: 2019-04-23
Status: ACTIVE



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RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.