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Gene: Flcn (folliculin) Rattus norvegicus
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Symbol: Flcn
Name: folliculin
Description: Predicted to contribute to GTPase activator activity. Predicted to be involved in several processes, including negative regulation of cellular metabolic process; positive regulation of cellular metabolic process; and regulation of intracellular signal transduction. Predicted to colocalize with the cell-cell contact zone and midbody. Used to study renal cell carcinoma. Human ortholog(s) of this gene implicated in Birt-Hogg-Dube syndrome; primary spontaneous pneumothorax; and renal cell carcinoma. Orthologous to human FLCN (folliculin); PARTICIPATES IN mTOR signaling pathway; renal cell carcinoma pathway; INTERACTS WITH 1-benzylpiperazine; 2,3,7,8-tetrachlorodibenzodioxine; 2,6-dinitrotoluene.
Type: protein-coding
RefSeq Status: PROVISIONAL
Also known as: Bhd; Birt-Hogg-Dube syndrome protein homolog; MGC94558
Orthologs:
Homo sapiens (human) : FLCN (folliculin)  HGNC  Alliance
Mus musculus (house mouse) : Flcn (folliculin)  MGI  Alliance
Chinchilla lanigera (long-tailed chinchilla) : Flcn (folliculin)
Pan paniscus (bonobo/pygmy chimpanzee) : FLCN (folliculin)
Canis lupus familiaris (dog) : FLCN (folliculin)
Ictidomys tridecemlineatus (thirteen-lined ground squirrel) : Flcn (folliculin)
Sus scrofa (pig) : FLCN (folliculin)
more info ...
Is Marker For: Strains:   BHD/Dspe  
Latest Assembly: Rnor_6.0 - RGSC Genome Assembly v6.0
Position:
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Rnor_6.01046,153,185 - 46,172,331 (-)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_5.01045,909,609 - 45,928,715 (-)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.41046,110,527 - 46,129,613 (-)NCBIRGSC3.4rn4RGSC3.4
RGSC_v3.11046,124,152 - 46,143,236 (-)NCBI
Celera1043,850,423 - 43,869,275 (-)NCBICelera
Cytogenetic Map10q22NCBI
JBrowse: View Region in Genome Browser (JBrowse)
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Additional Information

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More on Flcn
Alliance Gene
NCBI Gene
Ensembl Gene
JBrowse: rn5 rn6
NCBI Genome Data Viewer

RGD Object Information
RGD ID: 735088
Created: 2004-02-05
Species: Rattus norvegicus
Last Modified: 2019-08-20
Status: ACTIVE



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