Gene: Alox12 (arachidonate 12-lipoxygenase, 12S type) Rattus norvegicus
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Symbol: Alox12
Name: arachidonate 12-lipoxygenase, 12S type
Description: ENCODES a protein that exhibits arachidonate 12-lipoxygenase activity (ortholog); linoleate 13S-lipoxygenase activity (ortholog); INVOLVED IN aging; arachidonic acid metabolic process; cellular response to lipid; PARTICIPATES IN lipoxygenase mediated pathway of arachidonic acid metabolism; acetylsalicylic acid pharmacodynamics pathway; antipyrine drug pathway; ASSOCIATED WITH Carotid Artery Injuries; congestive heart failure; hypertension; FOUND IN cytoplasm; cytosol; sarcolemma; INTERACTS WITH (S)-10-[(DIMETHYLAMINO)METHYL]-4-ETHYL-4,9-DIHYDROXY-1H-PYRANO[3',4':6,7]INOLIZINO[1,2-B]-QUINOLINE-3,14(4H,12H)-DIONE; benoxaprofen; bisphenol A
Type: protein-coding
RefSeq Status: PROVISIONAL
Also known as: 12-LO; 12S-lipoxygenase; 12S-LOX; arachidonate 12-lipoxygenase; arachidonate 12-lipoxygenase, 12S-type; lipoxin synthase 12-LO; LOC287454; MGC187960; platelet 12-LOX; platelet-type lipoxygenase 12
Orthologs:
Homo sapiens (human) : ALOX12 (arachidonate 12-lipoxygenase, 12S type)  HGNC  Alliance
Mus musculus (house mouse) : Alox12 (arachidonate 12-lipoxygenase)  MGI  Alliance
Pan paniscus (bonobo/pygmy chimpanzee) : ALOX12 (arachidonate 12-lipoxygenase, 12S type)
Canis lupus familiaris (dog) : ALOX12 (arachidonate 12-lipoxygenase, 12S type)
Sus scrofa (pig) : ALOX12 (arachidonate 12-lipoxygenase, 12S type)
more info ...
Latest Assembly: Rnor_6.0 - RGSC Genome Assembly v6.0
Position:
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Rnor_6.01056,851,734 - 56,864,049 (-)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_5.01056,595,898 - 56,608,192 (-)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.41057,080,603 - 57,092,874 (-)NCBIRGSC3.4rn4RGSC3.4
RGSC_v3.11057,095,024 - 57,106,540 (-)NCBI
Celera1054,109,834 - 54,122,106 (-)NCBICelera
Cytogenetic Map10q24NCBI
JBrowse: View Region in Genome Browser (JBrowse)
Model

Annotation    (Toggle Annotation Detail/Summary View)

Disease Annotations
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Gene Ontology Annotations
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RGD Disease Portals

Genomics

Comparative Map Data
Position Markers
QTLs in Region (Rnor_6.0)
miRNA Target Status

Sequence

Nucleotide Sequences
Protein Sequences
Transcriptome
Promoters

Strain Variation

Strain Sequence Variants (Rnor 5.0)

Additional Information

External Database Links
Nomenclature History
  
More on Alox12
Alliance Gene
NCBI Gene
Ensembl Gene
JBrowse: rn5 rn6
NCBI Genome Data Viewer

RGD Object Information
RGD ID: 1311159
Created: 2005-01-12
Species: Rattus norvegicus
Last Modified: 2019-01-30
Status: ACTIVE



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