(+)-pilocarpine increases expression ISO RGD:732857 6480464 Pilocarpine results in increased expression of IL12B mRNA CTD PMID:15193289 (R)-mevalonic acid multiple interactions ISO RGD:732857 6480464 Mevalonic Acid inhibits the reaction [lipopolysaccharide, E coli O55-B5 results in increased expression of IL12B protein] CTD PMID:15187114 (S)-nicotine multiple interactions ISO RGD:732857 6480464 Acetylcysteine inhibits the reaction [Nicotine results in increased expression of IL12B mRNA] more ... CTD PMID:21237301 (S)-nicotine increases expression ISO RGD:732857 6480464 Nicotine results in increased expression of IL12B mRNA CTD PMID:21237301 1,3,5-trinitrobenzene multiple interactions ISO RGD:732857 6480464 Eicosapentaenoic Acid analog inhibits the reaction [sym-trinitrobenzene results in increased expression of IL12B mRNA] CTD PMID:15890784 1,3,5-trinitrobenzene decreases response to substance ISO RGD:732857 6480464 IL12B protein results in decreased susceptibility to sym-trinitrobenzene CTD PMID:11782017 1,3,5-trinitrobenzene increases expression ISO RGD:732857 6480464 sym-trinitrobenzene results in increased expression of IL12B mRNA CTD PMID:15890784 1,4-benzoquinone increases secretion ISO RGD:1353629 6480464 quinone results in increased secretion of IL12B protein CTD PMID:31958493 1-chloro-2,4,6-trinitrobenzene multiple interactions ISO RGD:732857 6480464 [Picryl Chloride co-treated with pirinixic acid] results in decreased expression of IL12B protein, PPARA protein affects the reaction [[Picryl Chloride co-treated with pirinixic acid] results in decreased expression of IL12B protein] CTD PMID:17371993 1-chloro-2,4,6-trinitrobenzene increases expression ISO RGD:732857 6480464 Picryl Chloride results in increased expression of IL12B mRNA CTD PMID:11708898 1-chloro-2,4-dinitrobenzene increases expression ISO RGD:732857 6480464 Dinitrochlorobenzene results in increased expression of IL12B mRNA, Dinitrochlorobenzene results in increased expression of IL12B protein CTD PMID:10199581 more ... 1-chloro-2,4-dinitrobenzene increases expression EXP 6480464 Dinitrochlorobenzene results in increased expression of IL12B mRNA CTD PMID:25449201 1-chloro-2,4-dinitrobenzene increases methylation ISO RGD:732857 6480464 Dinitrochlorobenzene results in increased methylation of IL12B gene CTD PMID:26732893 1-chloro-2,4-dinitrobenzene decreases methylation ISO RGD:732857 6480464 Dinitrochlorobenzene results in decreased methylation of IL12B gene CTD PMID:26732893 1-chloro-2,4-dinitrobenzene affects expression ISO RGD:732857 6480464 Dinitrochlorobenzene affects the expression of IL12B mRNA CTD PMID:22302311 1-chloro-2,4-dinitrobenzene increases secretion ISO RGD:732857 6480464 Dinitrochlorobenzene results in increased secretion of IL12B protein CTD PMID:10199581 1-fluoro-2,4-dinitrobenzene increases expression ISO RGD:732857 6480464 Dinitrofluorobenzene results in increased expression of IL12B mRNA CTD PMID:11708898 1-naphthyl isothiocyanate decreases expression EXP 6480464 1-Naphthylisothiocyanate results in decreased expression of IL12B mRNA CTD PMID:30723492 1-O-(alpha-D-galactosyl)-N-hexacosanoylphytosphingosine increases expression ISO RGD:1353629 6480464 KRN 7000 results in increased expression of IL12B protein CTD PMID:15867097 17beta-estradiol multiple interactions ISO RGD:1353629 6480464 [Estradiol co-treated with Bucladesine co-treated with Medroxyprogesterone Acetate] results in increased expression of IL12B mRNA more ... CTD PMID:20130130 , PMID:20823114 2,2',4,4'-Tetrabromodiphenyl ether multiple interactions ISO RGD:1353629 6480464 2 more ... CTD PMID:19211157 2,3,7,8-tetrachlorodibenzodioxine multiple interactions ISO RGD:732857 6480464 Tetrachlorodibenzodioxin inhibits the reaction [[CpG ODN 1826 binds to and results in increased activity of TLR9 protein] results in increased secretion of [IL12A protein binds to IL12B protein]] more ... CTD PMID:21097750 2,3,7,8-tetrachlorodibenzodioxine increases expression EXP 6480464 Tetrachlorodibenzodioxin results in increased expression of IL12B mRNA CTD PMID:15644576 2,4,6-trinitrobenzenesulfonic acid decreases response to substance ISO RGD:732857 6480464 IL12B protein results in decreased susceptibility to Trinitrobenzenesulfonic Acid CTD PMID:11782017 2,4,6-trinitrobenzenesulfonic acid increases expression ISO RGD:732857 6480464 Trinitrobenzenesulfonic Acid results in increased expression of IL12B mRNA, Trinitrobenzenesulfonic Acid results in increased expression of IL12B protein CTD PMID:17375199 , PMID:23596210 2,4,6-trinitrobenzenesulfonic acid multiple interactions ISO RGD:732857 6480464 icilin inhibits the reaction [Trinitrobenzenesulfonic Acid results in increased expression of IL12B protein] CTD PMID:23596210 2,4,6-trinitrobenzenesulfonic acid increases expression EXP 6480464 Trinitrobenzenesulfonic Acid results in increased expression of IL12B mRNA CTD PMID:16867261 2,4,6-trinitrobenzenesulfonic acid multiple interactions EXP 6480464 Curcumin inhibits the reaction [Trinitrobenzenesulfonic Acid results in increased expression of IL12B mRNA], Dexamethasone inhibits the reaction [Trinitrobenzenesulfonic Acid results in increased expression of IL12B mRNA] CTD PMID:16867261 2-acetamidofluorene increases expression EXP 6480464 2-Acetylaminofluorene results in increased expression of IL12B protein CTD PMID:25051504 2-amino-2-deoxy-D-galactopyranose multiple interactions ISO RGD:732857 6480464 [LEP gene mutant form results in increased susceptibility to Galactosamine] which results in increased expression of IL12B mRNA, [LEPR gene mutant form results in increased susceptibility to Galactosamine] which results in increased expression of IL12B mRNA CTD PMID:19913045 2-amino-2-deoxy-D-galactopyranose multiple interactions EXP 6480464 mangiferin inhibits the reaction [Galactosamine results in increased expression of IL12B mRNA] CTD PMID:22310181 2-amino-2-deoxy-D-galactopyranose increases expression EXP 6480464 Galactosamine results in increased expression of IL12B mRNA CTD PMID:22310181 2-tert-butylhydroquinone multiple interactions ISO RGD:1353629 6480464 2-tert-butylhydroquinone inhibits the reaction [lipopolysaccharide, E coli O55-B5 results in increased expression of IL12B mRNA] more ... CTD PMID:25680285 2-trans,6-trans,10-trans-geranylgeranyl diphosphate multiple interactions ISO RGD:732857 6480464 geranylgeranyl pyrophosphate inhibits the reaction [lipopolysaccharide, E coli O55-B5 results in increased expression of IL12B protein] CTD PMID:15187114 2-trans,6-trans-farnesyl diphosphate multiple interactions ISO RGD:732857 6480464 farnesyl pyrophosphate inhibits the reaction [lipopolysaccharide, E coli O55-B5 results in increased expression of IL12B protein] CTD PMID:15187114 3',5'-cyclic AMP multiple interactions ISO RGD:1353629 6480464 Cyclic AMP promotes the reaction [[Histamine results in increased activity of HRH2 protein] which results in decreased expression of IL12B protein] CTD PMID:15843518 3,3',4,4',5-pentachlorobiphenyl multiple interactions ISO RGD:732857 6480464 3 more ... CTD PMID:29216392 3,5-diethoxycarbonyl-1,4-dihydrocollidine multiple interactions ISO RGD:732857 6480464 [NFE2L2 gene mutant form results in increased susceptibility to 3 more ... CTD PMID:30825315 3-\{1-[3-(dimethylamino)propyl]-1H-indol-3-yl\}-4-(1H-indol-3-yl)-1H-pyrrole-2,5-dione multiple interactions ISO RGD:732857 6480464 bisindolylmaleimide I inhibits the reaction [Lipopolysaccharides results in increased secretion of IL12B protein] CTD PMID:16330529 3-iodobenzyl-5'-N-methylcarboxamidoadenosine multiple interactions ISO RGD:1353629 6480464 N(6)-(3-iodobenzyl)-5'-N-methylcarboxamidoadenosine results in decreased expression of [IL12A protein binds to IL12B protein] more ... CTD PMID:16116186 3-phenylprop-2-enal decreases expression ISO RGD:732857 6480464 cinnamic aldehyde results in decreased expression of IL12B mRNA CTD PMID:28219650 4,4'-diaminodiphenylmethane decreases expression ISO RGD:732857 6480464 4, 4'-diaminodiphenylmethane results in decreased expression of IL12B mRNA CTD PMID:18648102 4,4'-diisothiocyano-trans-stilbene-2,2'-disulfonic acid multiple interactions ISO RGD:732857 6480464 4 more ... CTD PMID:11907163 4-(ethoxymethylene)-2-phenyloxazol-5-one increases expression ISO RGD:732857 6480464 Oxazolone results in increased expression of IL12B mRNA, Oxazolone results in increased expression of IL12B protein CTD PMID:11379042 more ... 4-methylhistamine multiple interactions ISO RGD:1353629 6480464 4-methylhistamine inhibits the reaction [IL18 protein results in increased expression of [IL12A protein binds to IL12B protein]] CTD PMID:11752121 , PMID:12364868 4-nitroquinoline N-oxide decreases expression ISO RGD:732857 6480464 4-Nitroquinoline-1-oxide results in decreased expression of IL12B mRNA CTD PMID:22561872 4-nitroquinoline N-oxide increases expression ISO RGD:732857 6480464 4-Nitroquinoline-1-oxide results in increased expression of IL12B mRNA CTD PMID:22561872 5-[3-(tert-butylamino)-2-hydroxypropoxy]-1,2,3,4-tetrahydronaphthalene-2,3-diol multiple interactions ISO RGD:732857 6480464 [Nadolol co-treated with Mifepristone] inhibits the reaction [methyldithiocarbamate inhibits the reaction [Lipopolysaccharides results in increased secretion of IL12B protein]] CTD PMID:16321413 5-azacytidine increases expression ISO RGD:1353629 6480464 Azacitidine results in increased expression of IL12B mRNA CTD PMID:20823114 5-fluorouracil decreases expression ISO RGD:732857 6480464 Fluorouracil results in decreased expression of IL12B protein CTD PMID:15754409 8-OH-DPAT multiple interactions ISO RGD:1353629 6480464 8-Hydroxy-2-(di-n-propylamino)tetralin promotes the reaction [Lipopolysaccharides results in increased secretion of IL12B protein] CTD PMID:15802305 9-cis-retinoic acid multiple interactions ISO RGD:1353629 6480464 Alitretinoin inhibits the reaction [Lipopolysaccharides results in increased secretion of [IL12A protein binds to IL12B protein]], Alitretinoin results in decreased expression of [IL12A protein binds to IL12B protein] CTD PMID:17118196 , PMID:17475839 9-cis-retinoic acid multiple interactions ISO RGD:732857 6480464 Alitretinoin inhibits the reaction [Lipopolysaccharides results in increased secretion of IL12B protein] CTD PMID:16303184 acetylsalicylic acid multiple interactions ISO RGD:1353629 6480464 Aspirin inhibits the reaction [[Lipopolysaccharides co-treated with IFNG protein] results in increased secretion of [IL12A protein binds to IL12B protein]] CTD PMID:15379866 acrolein multiple interactions ISO RGD:732857 6480464 CD8A gene mutant form inhibits the reaction [Acrolein results in increased expression of IL12B mRNA] CTD PMID:17950725 acrolein increases expression ISO RGD:732857 6480464 Acrolein results in increased expression of IL12B mRNA CTD PMID:17950725 adenosine decreases expression ISO RGD:732857 6480464 Adenosine results in decreased expression of IL12B protein CTD PMID:11023991 adenosine multiple interactions ISO RGD:732857 6480464 Adenosine inhibits the reaction [Lipopolysaccharides results in increased secretion of IL12B protein] CTD PMID:11023991 adenosine 5'-[gamma-thio]triphosphate increases expression ISO RGD:732857 6480464 adenosine 5'-O-(3-thiotriphosphate) results in increased expression of IL12B protein CTD PMID:15944274 aflatoxin B1 multiple interactions ISO RGD:732857 6480464 [aflatoxin B2 co-treated with Aflatoxin B1] inhibits the reaction [Lipopolysaccharides results in increased secretion of IL12B protein], [aflatoxin G1 co-treated with Aflatoxin B1] inhibits the reaction [Lipopolysaccharides results in increased secretion of IL12B protein] CTD PMID:22445859 aflatoxin B2 multiple interactions ISO RGD:732857 6480464 [aflatoxin B2 co-treated with Aflatoxin B1] inhibits the reaction [Lipopolysaccharides results in increased secretion of IL12B protein] more ... CTD PMID:22445859 Aflatoxin G1 multiple interactions ISO RGD:732857 6480464 [aflatoxin G1 co-treated with Aflatoxin B1] inhibits the reaction [Lipopolysaccharides results in increased secretion of IL12B protein], [aflatoxin G1 co-treated with aflatoxin B2] inhibits the reaction [Lipopolysaccharides results in increased secretion of IL12B protein] CTD PMID:22445859 aldehydo-D-glucose multiple interactions ISO RGD:732857 6480464 2-chloro-4'-methoxychalcone inhibits the reaction [Glucose results in increased expression of IL12B mRNA] CTD PMID:21988173 aldehydo-D-glucose increases expression ISO RGD:732857 6480464 Glucose results in increased expression of IL12B mRNA CTD PMID:21988173 all-trans-retinoic acid multiple interactions ISO RGD:1353629 6480464 RARA protein affects the reaction [Tretinoin results in decreased secretion of [IL12A protein binds to IL12B protein]] more ... CTD PMID:16872382 more ... all-trans-retinoic acid decreases expression ISO RGD:1353629 6480464 Tretinoin results in decreased expression of IL12B mRNA CTD PMID:15189689 more ... alloxan decreases expression ISO RGD:732857 6480464 Alloxan results in decreased expression of IL12B protein CTD PMID:16249388 alpha-hexylcinnamaldehyde affects expression ISO RGD:732857 6480464 hexyl cinnamic aldehyde affects the expression of IL12B mRNA CTD PMID:22302311 aluminium atom multiple interactions ISO RGD:732857 6480464 [Aluminum co-treated with Copper] inhibits the reaction [lipopolysaccharide, Escherichia coli O111 B4 results in increased expression of IL12B mRNA] CTD PMID:23690655 aluminium(0) multiple interactions ISO RGD:732857 6480464 [Aluminum co-treated with Copper] inhibits the reaction [lipopolysaccharide, Escherichia coli O111 B4 results in increased expression of IL12B mRNA] CTD PMID:23690655 amiloride multiple interactions ISO RGD:732857 6480464 Amiloride inhibits the reaction [[lipopolysaccharide, E coli O55-B5 co-treated with IFNG protein] results in increased secretion of IL12B protein] CTD PMID:11420121 ammonium chloride affects expression EXP 6480464 Ammonium Chloride affects the expression of IL12B mRNA CTD PMID:16483693 anandamide multiple interactions ISO RGD:732857 6480464 [OMDM-1 cpd co-treated with anandamide] inhibits the reaction [Lipopolysaccharides results in increased secretion of IL12B protein], anandamide inhibits the reaction [Lipopolysaccharides results in increased secretion of IL12B protein] CTD PMID:15748152 anthra[1,9-cd]pyrazol-6(2H)-one multiple interactions ISO RGD:1353629 6480464 pyrazolanthrone inhibits the reaction [nickel sulfate results in increased secretion of IL12B protein] CTD PMID:19101624 anthra[1,9-cd]pyrazol-6(2H)-one multiple interactions ISO RGD:732857 6480464 pyrazolanthrone promotes the reaction [Lipopolysaccharides results in increased secretion of IL12B protein] CTD PMID:15778123 anthranilic acid multiple interactions ISO RGD:1353629 6480464 anthranilic acid analog inhibits the reaction [[IL12A protein binds to IL12B protein] which results in increased secretion of IFNG protein] CTD PMID:15799959 antimony(0) affects response to substance ISO RGD:732857 6480464 IL12B protein affects the susceptibility to Antimony CTD PMID:11023473 arachidonic acid multiple interactions ISO RGD:1353629 6480464 Arachidonic Acid inhibits the reaction [Lipopolysaccharides results in increased expression of IL12B mRNA] CTD PMID:15684433 arsenite(3-) multiple interactions ISO RGD:1353629 6480464 arsenite inhibits the reaction [[IFNG protein co-treated with lipopolysaccharide, E coli O55-B5] results in increased expression of IL12B mRNA] more ... CTD PMID:25680285 arsenite(3-) multiple interactions ISO RGD:732857 6480464 arsenite inhibits the reaction [lipopolysaccharide, E coli O55-B5 results in increased expression of IL12B mRNA], NFE2L2 gene mutant form inhibits the reaction [arsenite inhibits the reaction [lipopolysaccharide, E coli O55-B5 results in increased expression of IL12B mRNA]] CTD PMID:25680285 ATP multiple interactions ISO RGD:1353629 6480464 Adenosine Triphosphate inhibits the reaction [Lipopolysaccharides results in increased expression of IL12B protein] CTD PMID:17707769 azathioprine multiple interactions ISO RGD:1353629 6480464 Azathioprine results in increased expression of [IL12A protein binds to IL12B protein] CTD PMID:19584951 Benzamil multiple interactions ISO RGD:732857 6480464 benzamil inhibits the reaction [[lipopolysaccharide, E coli O55-B5 co-treated with IFNG protein] results in increased secretion of IL12B protein] CTD PMID:11420121 benzene multiple interactions ISO RGD:732857 6480464 Benzene metabolite inhibits the reaction [Lipopolysaccharides results in increased expression of IL12B mRNA] CTD PMID:15894107 benzene increases expression ISO RGD:732857 6480464 Benzene metabolite results in increased expression of IL12B mRNA CTD PMID:15894107 benzo[a]pyrene multiple interactions ISO RGD:732857 6480464 [Benzo(a)pyrene co-treated with Lipopolysaccharides] results in increased expression of IL12B mRNA CTD PMID:17275222 benzo[a]pyrene decreases expression ISO RGD:732857 6480464 Benzo(a)pyrene results in decreased expression of IL12B mRNA CTD PMID:21569818 beta-D-glucan multiple interactions ISO RGD:1353629 6480464 [beta-Glucans co-treated with resiquimod] results in increased expression of [IL12A protein binds to IL12B protein] more ... CTD PMID:18490488 beta-D-glucan increases expression ISO RGD:1353629 6480464 beta-Glucans results in increased expression of IL12B protein CTD PMID:18490488 betulin multiple interactions ISO RGD:732857 6480464 betulin results in increased secretion of [IL12A protein binds to IL12B protein] CTD PMID:25756279 bis(2-chloroethyl) sulfide increases expression ISO RGD:732857 6480464 Mustard Gas results in increased expression of IL12B mRNA CTD PMID:15674843 bisphenol A decreases expression EXP 6480464 bisphenol A results in decreased expression of IL12B mRNA CTD PMID:18569609 bisphenol A multiple interactions ISO RGD:732857 6480464 [bisphenol A affects the susceptibility to Ovalbumin] results in decreased expression of and results in decreased secretion of [IL12A protein binds to IL12B protein] CTD PMID:29737898 bisphenol A increases expression ISO RGD:732857 6480464 bisphenol A results in increased expression of IL12B mRNA CTD PMID:31574244 bisphenol A affects expression EXP 6480464 bisphenol A affects the expression of IL12B mRNA CTD PMID:25181051 bleomycin A2 increases expression ISO RGD:732857 6480464 Bleomycin results in increased expression of IL12B mRNA, Bleomycin results in increased expression of IL12B protein CTD PMID:11350791 Brevetoxin B increases expression ISO RGD:1353629 6480464 brevetoxin 2 results in increased expression of IL12B mRNA CTD PMID:20498034 bromosulfophthalein multiple interactions ISO RGD:732857 6480464 Sulfobromophthalein inhibits the reaction [[Lipopolysaccharides co-treated with IFNG protein] results in increased expression of IL12B protein] CTD PMID:11907163 bryostatin 1 decreases expression ISO RGD:1353629 6480464 bryostatin 1 analog results in decreased expression of IL12B mRNA CTD PMID:15614042 bryostatin 1 increases expression ISO RGD:1353629 6480464 bryostatin 1 results in increased expression of IL12B mRNA CTD PMID:15614042 bucladesine multiple interactions ISO RGD:1353629 6480464 [Estradiol co-treated with Bucladesine co-treated with Medroxyprogesterone Acetate] results in increased expression of IL12B mRNA CTD PMID:20823114 cadmium dichloride decreases expression ISO RGD:732857 6480464 Cadmium Chloride results in decreased expression of IL12B protein CTD PMID:24583143 cadmium dichloride increases methylation EXP 6480464 Cadmium Chloride results in increased methylation of IL12B promoter CTD PMID:22457795 caffeine multiple interactions ISO RGD:732857 6480464 Caffeine inhibits the reaction [lipopolysaccharide, Escherichia coli O111 B4 results in increased expression of IL12B mRNA] CTD PMID:26852703 calcitriol decreases expression ISO RGD:732857 6480464 Calcitriol results in decreased expression of IL12B protein CTD PMID:15939587 capsaicin decreases expression ISO RGD:1353629 6480464 Capsaicin results in decreased expression of IL12B mRNA CTD PMID:18533110 carbamate ester increases expression ISO RGD:1353629 6480464 Carbamates analog results in increased expression of IL12B protein CTD PMID:19111005 , PMID:19376255 carbon monoxide multiple interactions ISO RGD:732857 6480464 Carbon Monoxide inhibits the reaction [IFNG protein promotes the reaction [Lipopolysaccharides results in increased expression of IL12B protein]] CTD PMID:16365149 carbon nanotube multiple interactions ISO RGD:1353629 6480464 [[Poly I-C binds to and results in increased activity of TLR3 protein] which co-treated with Nanotubes, Carbon] results in increased secretion of IL12B protein more ... CTD PMID:23266719 carbon nanotube increases expression ISO RGD:732857 6480464 Nanotubes, Carbon results in increased expression of IL12B mRNA CTD PMID:25554681 carbon nanotube affects expression ISO RGD:732857 6480464 Nanotubes, Carbon affects the expression of IL12B mRNA CTD PMID:23845593 carmustine multiple interactions ISO RGD:732857 6480464 Carmustine promotes the reaction [Lipopolysaccharides results in increased expression of IL12B protein] CTD PMID:12688424 carvedilol multiple interactions ISO RGD:1353629 6480464 carvedilol promotes the reaction [Hemagglutinins results in increased expression of [IL12A protein binds to IL12B protein]], carvedilol promotes the reaction [Lipopolysaccharides results in increased expression of [IL12A protein binds to IL12B protein]] CTD PMID:15229385 choline multiple interactions ISO RGD:732857 6480464 [Dietary Fats co-treated with Choline deficiency] results in increased expression of IL12B protein, [Methionine deficiency co-treated with Choline deficiency co-treated with Folic Acid deficiency] results in increased expression of IL12B mRNA CTD PMID:20938992 , PMID:29246445 ciprofibrate multiple interactions ISO RGD:732857 6480464 ciprofibrate inhibits the reaction [Lipopolysaccharides results in increased secretion of IL12B protein] CTD PMID:15968640 Colforsin dapropate hydrochloride multiple interactions ISO RGD:732857 6480464 Colforsin inhibits the reaction [oxophenylarsine promotes the reaction [Lipopolysaccharides results in increased expression of IL12B protein]], Colforsin results in increased expression of [IL12B protein binds to IL23A protein] CTD PMID:15180965 , PMID:20512473 Colforsin dapropate hydrochloride increases expression ISO RGD:732857 6480464 Colforsin results in increased expression of IL12B protein CTD PMID:10996031 , PMID:15180965 copper atom multiple interactions ISO RGD:732857 6480464 [Aluminum co-treated with Copper] inhibits the reaction [lipopolysaccharide, Escherichia coli O111 B4 results in increased expression of IL12B mRNA], [ATP7A gene mutant form results in increased abundance of Copper] which results in increased expression of IL12B mRNA CTD PMID:15467011 , PMID:23690655 copper atom increases secretion ISO RGD:732857 6480464 Copper results in increased secretion of IL12B protein CTD PMID:19635393 copper(0) multiple interactions ISO RGD:732857 6480464 [Aluminum co-treated with Copper] inhibits the reaction [lipopolysaccharide, Escherichia coli O111 B4 results in increased expression of IL12B mRNA], [ATP7A gene mutant form results in increased abundance of Copper] which results in increased expression of IL12B mRNA CTD PMID:15467011 , PMID:23690655 copper(0) increases secretion ISO RGD:732857 6480464 Copper results in increased secretion of IL12B protein CTD PMID:19635393 curcumin multiple interactions EXP 6480464 Curcumin inhibits the reaction [Trinitrobenzenesulfonic Acid results in increased expression of IL12B mRNA] CTD PMID:16867261 curcumin multiple interactions ISO RGD:1353629 6480464 Curcumin inhibits the reaction [Oxygen deficiency results in increased expression of IL12B mRNA] CTD PMID:23452621 cyclophosphamide affects expression ISO RGD:732857 6480464 Cyclophosphamide affects the expression of IL12B mRNA CTD PMID:18957084 cyclophosphamide multiple interactions ISO RGD:732857 6480464 [Doxorubicin co-treated with Cyclophosphamide] results in decreased expression of [IL12A protein binds to IL12B protein] CTD PMID:29228376 cyclophosphamide increases expression ISO RGD:732857 6480464 Cyclophosphamide results in increased expression of IL12B mRNA CTD PMID:15331540 , PMID:22842586 cyclosporin A multiple interactions ISO RGD:732857 6480464 Cyclosporine inhibits the reaction [Zymosan results in increased expression of [IL12A protein binds to IL12B protein]] CTD PMID:17312158 D-glucose multiple interactions ISO RGD:732857 6480464 2-chloro-4'-methoxychalcone inhibits the reaction [Glucose results in increased expression of IL12B mRNA] CTD PMID:21988173 D-glucose increases expression ISO RGD:732857 6480464 Glucose results in increased expression of IL12B mRNA CTD PMID:21988173 daidzein multiple interactions ISO RGD:732857 6480464 daidzein inhibits the reaction [Lipopolysaccharides results in increased expression of IL12B mRNA], daidzein inhibits the reaction [Lipopolysaccharides results in increased expression of IL12B protein] CTD PMID:21945492 delta-tocotrienol decreases expression ISO RGD:732857 6480464 tocotrienol, delta results in decreased expression of IL12B mRNA CTD PMID:22185406 delta-tocotrienol multiple interactions ISO RGD:732857 6480464 tocotrienol, delta inhibits the reaction [Lipopolysaccharides results in increased expression of IL12B mRNA] CTD PMID:22185406 deoxynivalenol increases expression ISO RGD:732857 6480464 deoxynivalenol results in increased expression of IL12B mRNA CTD PMID:9194413 , PMID:9707511 deoxynivalenol multiple interactions ISO RGD:732857 6480464 [Lipopolysaccharides co-treated with deoxynivalenol] results in increased expression of IL12B protein CTD PMID:28935500 dexamethasone multiple interactions ISO RGD:732857 6480464 Dexamethasone inhibits the reaction [Lipopolysaccharides results in increased expression of IL12B mRNA], Dexamethasone inhibits the reaction [Lipopolysaccharides results in increased expression of IL12B protein] CTD PMID:16880258 , PMID:27568862 dexamethasone multiple interactions ISO RGD:1353629 6480464 Dexamethasone inhibits the reaction [Lipopolysaccharides results in increased expression of IL12B protein] CTD PMID:27568862 dexamethasone increases expression ISO RGD:732857 6480464 Dexamethasone results in increased expression of IL12B mRNA CTD PMID:22842586 dexamethasone decreases secretion ISO RGD:732857 6480464 Dexamethasone results in decreased secretion of IL12B protein CTD PMID:28003376 dexamethasone multiple interactions EXP 6480464 Dexamethasone inhibits the reaction [Trinitrobenzenesulfonic Acid results in increased expression of IL12B mRNA] CTD PMID:16867261 diazinon affects expression ISO RGD:732857 6480464 Diazinon affects the expression of IL12B protein CTD PMID:17499902 diazinon decreases expression ISO RGD:732857 6480464 Diazinon results in decreased expression of IL12B mRNA CTD PMID:17499902 dichlorine increases expression ISO RGD:732857 6480464 Chlorine results in increased expression of IL12B protein CTD PMID:23146759 diltiazem multiple interactions ISO RGD:1353629 6480464 Diltiazem inhibits the reaction [[NFKB1 protein binds to RELA protein] which binds to IL12B promoter] more ... CTD PMID:15652234 diltiazem decreases expression ISO RGD:1353629 6480464 Diltiazem results in decreased expression of IL12B mRNA CTD PMID:15652234 Dimaprit multiple interactions ISO RGD:1353629 6480464 Dimaprit inhibits the reaction [IL18 protein results in increased expression of [IL12A protein binds to IL12B protein]] CTD PMID:11752121 , PMID:12364868 dioxygen decreases expression ISO RGD:732857 6480464 Oxygen deficiency results in decreased expression of IL12B mRNA CTD PMID:24205000 dioxygen increases expression ISO RGD:1353629 6480464 Oxygen deficiency results in increased expression of IL12B mRNA CTD PMID:23452621 dioxygen multiple interactions ISO RGD:1353629 6480464 3 more ... CTD PMID:23452621 doxorubicin multiple interactions ISO RGD:732857 6480464 [Doxorubicin co-treated with Cyclophosphamide] results in decreased expression of [IL12A protein binds to IL12B protein] CTD PMID:29228376 estriol decreases expression ISO RGD:732857 6480464 Estriol results in decreased expression of IL12B mRNA CTD PMID:21317386 ethanol affects secretion ISO RGD:732857 6480464 Ethanol affects the secretion of IL12B protein CTD PMID:20624996 ethanol multiple interactions ISO RGD:732857 6480464 Ethanol inhibits the reaction [Lipopolysaccharides results in increased expression of [IL12A protein binds to IL12B protein]] more ... CTD PMID:10798593 , PMID:19500611 ethionamide increases expression EXP 6480464 Ethionamide results in increased expression of IL12B protein CTD PMID:25051504 ethylisopropylamiloride multiple interactions ISO RGD:732857 6480464 ethylisopropylamiloride inhibits the reaction [[lipopolysaccharide, E coli O55-B5 co-treated with IFNG protein] results in increased secretion of IL12B protein] CTD PMID:11420121 eugenol multiple interactions ISO RGD:732857 6480464 Eugenol inhibits the reaction [Nicotine results in increased expression of IL12B mRNA], Eugenol inhibits the reaction [Nicotine results in increased secretion of [IL12A protein co-treated with IL12B protein]] CTD PMID:21237301 famotidine multiple interactions ISO RGD:1353629 6480464 Famotidine inhibits the reaction [Histamine inhibits the reaction [IL18 protein results in increased expression of [IL12A protein binds to IL12B protein]]] CTD PMID:11752121 , PMID:12364868 farnesyl diphosphate multiple interactions ISO RGD:732857 6480464 farnesyl pyrophosphate inhibits the reaction [lipopolysaccharide, E coli O55-B5 results in increased expression of IL12B protein] CTD PMID:15187114 fenofibrate multiple interactions ISO RGD:732857 6480464 Fenofibrate inhibits the reaction [Lipopolysaccharides results in increased secretion of IL12B protein] CTD PMID:15968640 ferulic acid multiple interactions ISO RGD:732857 6480464 ferulic acid inhibits the reaction [Imiquimod results in increased expression of IL12B mRNA] CTD PMID:31054998 flavonoids increases expression EXP 6480464 Flavonoids results in increased expression of IL12B mRNA CTD PMID:18035473 folic acid multiple interactions ISO RGD:732857 6480464 [Methionine deficiency co-treated with Choline deficiency co-treated with Folic Acid deficiency] results in increased expression of IL12B mRNA CTD PMID:20938992 formaldehyde increases expression ISO RGD:732857 6480464 Formaldehyde results in increased expression of IL12B mRNA CTD PMID:12161283 fragrance increases expression ISO RGD:1353629 6480464 Perfume results in increased expression of IL12B mRNA CTD PMID:24768652 gemfibrozil multiple interactions ISO RGD:732857 6480464 Gemfibrozil inhibits the reaction [Lipopolysaccharides results in increased secretion of IL12B protein] CTD PMID:15968640 genistein multiple interactions ISO RGD:1353629 6480464 Genistein inhibits the reaction [Oxygen deficiency results in increased expression of IL12B mRNA] CTD PMID:23452621 genistein increases expression ISO RGD:732857 6480464 Genistein results in increased expression of IL12B mRNA CTD PMID:32186404 gentamycin decreases expression EXP 6480464 Gentamicins results in decreased expression of IL12B protein CTD PMID:25051504 glucose multiple interactions ISO RGD:732857 6480464 2-chloro-4'-methoxychalcone inhibits the reaction [Glucose results in increased expression of IL12B mRNA] CTD PMID:21988173 glucose increases expression ISO RGD:732857 6480464 Glucose results in increased expression of IL12B mRNA CTD PMID:21988173 glucuronoxylomannan multiple interactions ISO RGD:1353629 6480464 glucuronoxylomannan results in decreased secretion of [IL12A protein binds to IL12B protein] CTD PMID:12864811 glyburide multiple interactions ISO RGD:732857 6480464 Glyburide inhibits the reaction [[Lipopolysaccharides co-treated with IFNG protein] results in increased expression of IL12B protein], Glyburide inhibits the reaction [Lipopolysaccharides results in increased expression of IL12B protein] CTD PMID:11907163 glycyrrhizinic acid multiple interactions ISO RGD:732857 6480464 [Glycyrrhizic Acid co-treated with Lipopolysaccharides] results in increased expression of [IL12A protein binds to IL12B protein] more ... CTD PMID:11412311 helenalin multiple interactions ISO RGD:1353629 6480464 helenalin inhibits the reaction [Drugs, Chinese Herbal results in increased secretion of [IL12A protein binds to IL12B protein]] more ... CTD PMID:15894585 histamine decreases expression ISO RGD:1353629 6480464 Histamine results in decreased expression of IL12B mRNA, Histamine results in decreased expression of IL12B protein CTD PMID:9819373 histamine increases expression ISO RGD:1353629 6480464 Histamine results in increased expression of IL12B protein CTD PMID:15843518 histamine multiple interactions ISO RGD:1353629 6480464 [Histamine results in increased activity of HRH2 protein] which results in decreased expression of IL12B protein more ... CTD PMID:11752121 more ... hyaluronic acid increases secretion ISO RGD:732857 6480464 Hyaluronic Acid analog results in increased secretion of IL12B protein CTD PMID:9278343 hydrogen peroxide decreases expression ISO RGD:732857 6480464 Hydrogen Peroxide results in decreased expression of IL12B protein CTD PMID:16249388 hydrogen peroxide multiple interactions ISO RGD:732857 6480464 Hydrogen Peroxide inhibits the reaction [N-bromotaurine inhibits the reaction [Lipopolysaccharides results in increased secretion of IL12B protein]] more ... CTD PMID:15723204 , PMID:16249388 hydroquinone multiple interactions ISO RGD:732857 6480464 hydroquinone inhibits the reaction [Lipopolysaccharides results in increased expression of IL12B mRNA] CTD PMID:15894107 , PMID:17464197 hydroquinone increases expression ISO RGD:732857 6480464 hydroquinone results in increased expression of IL12B mRNA CTD PMID:15894107 hydroxychloroquine increases expression ISO RGD:732857 6480464 Hydroxychloroquine results in increased expression of IL12B mRNA CTD PMID:25321315 Ibudilast decreases expression ISO RGD:732857 6480464 ibudilast results in decreased expression of IL12B mRNA CTD PMID:14664469 Ibudilast multiple interactions ISO RGD:732857 6480464 ibudilast results in decreased expression of [IL12A protein binds to IL12B protein] CTD PMID:14664469 imiquimod multiple interactions ISO RGD:732857 6480464 [Imiquimod binds to and results in increased activity of TLR7 protein] results in increased secretion of [IL12A protein binds to IL12B protein] more ... CTD PMID:21097750 more ... imiquimod increases secretion ISO RGD:732857 6480464 Imiquimod results in increased secretion of IL12B protein CTD PMID:22916010 imiquimod increases expression ISO RGD:732857 6480464 Imiquimod results in increased expression of IL12B mRNA CTD PMID:31054998 indometacin increases expression EXP 6480464 Indomethacin results in increased expression of IL12B protein CTD PMID:25051504 indometacin multiple interactions ISO RGD:732857 6480464 Indomethacin results in increased expression of [IL12A protein binds to IL12B protein] CTD PMID:11703811 iron atom multiple interactions ISO RGD:1353629 6480464 Iron affects the reaction [[IL12A protein binds to IL12B protein] which results in increased secretion of IFNG protein] CTD PMID:15799959 iron(0) multiple interactions ISO RGD:1353629 6480464 Iron affects the reaction [[IL12A protein binds to IL12B protein] which results in increased secretion of IFNG protein] CTD PMID:15799959 isocyanates increases expression ISO RGD:1353629 6480464 Isocyanates analog results in increased expression of IL12B protein CTD PMID:19111005 isoniazide increases secretion ISO RGD:1353629 6480464 Isoniazid results in increased secretion of IL12B protein CTD PMID:28444390 isoprenaline increases expression ISO RGD:1353629 6480464 Isoproterenol results in increased expression of IL12B protein CTD PMID:24286936 L-methionine multiple interactions ISO RGD:732857 6480464 [Methionine deficiency co-treated with Choline deficiency co-treated with Folic Acid deficiency] results in increased expression of IL12B mRNA CTD PMID:20938992 lead(0) multiple interactions ISO RGD:732857 6480464 Lead results in increased expression of and results in increased secretion of [IL12A protein binds to IL12B protein] CTD PMID:28973681 lead(2+) multiple interactions ISO RGD:732857 6480464 Lead results in increased expression of and results in increased secretion of [IL12A protein binds to IL12B protein] CTD PMID:28973681 lenalidomide multiple interactions ISO RGD:732857 6480464 lenalidomide inhibits the reaction [SOD1 gene mutant form results in increased expression of IL12B mRNA] CTD PMID:16510725 leukotriene B4 multiple interactions ISO RGD:732857 6480464 Leukotriene B4 inhibits the reaction [Lipopolysaccharides results in increased secretion of IL12B protein] CTD PMID:16313356 leukotriene D4 multiple interactions ISO RGD:1353629 6480464 BAY u9773 inhibits the reaction [Leukotriene D4 results in increased secretion of [IL12A protein binds to IL12B protein]] more ... CTD PMID:19118273 lipid As increases expression ISO RGD:1353629 6480464 Lipid A results in increased expression of IL12B mRNA CTD PMID:16299289 lipid As multiple interactions ISO RGD:1353629 6480464 [Acetylmuramyl-Alanyl-Isoglutamine co-treated with Lipid A] results in increased expression of [IL12A protein binds to IL12B protein] more ... CTD PMID:16299289 lipoarabinomannan multiple interactions ISO RGD:732857 6480464 lipoarabinomannan inhibits the reaction [Lipopolysaccharides results in increased expression of IL12B protein] CTD PMID:16263713 lipophosphoglycan multiple interactions ISO RGD:1353629 6480464 [lipopeptidophosphoglycan binds to and results in increased activity of TLR2 protein] which results in increased secretion of IL12B protein, [lipopeptidophosphoglycan binds to and results in increased activity of TLR4 protein] which results in increased secretion of IL12B protein CTD PMID:15910421 lipopolysaccharide multiple interactions ISO RGD:732857 6480464 1 more ... CTD PMID:10415056 more ... lipopolysaccharide increases secretion ISO RGD:732857 6480464 Lipopolysaccharides results in increased secretion of IL12B protein CTD PMID:10415056 more ... lipopolysaccharide increases expression ISO RGD:732857 6480464 Lipopolysaccharides results in increased expression of IL12B mRNA, Lipopolysaccharides results in increased expression of IL12B protein CTD PMID:10415056 more ... lipopolysaccharide increases secretion ISO RGD:1353629 6480464 Lipopolysaccharides results in increased secretion of IL12B protein CTD PMID:11369638 more ... lipopolysaccharide increases expression ISO RGD:1353629 6480464 Lipopolysaccharides results in increased expression of IL12B mRNA, Lipopolysaccharides results in increased expression of IL12B protein CTD PMID:11717198 more ... lipopolysaccharide multiple interactions ISO RGD:1353629 6480464 (+)-JQ1 compound inhibits the reaction [Lipopolysaccharides results in increased expression of IL12B mRNA] more ... CTD PMID:10651989 more ... lithium atom multiple interactions ISO RGD:732857 6480464 Lithium inhibits the reaction [Lipopolysaccharides results in increased expression of IL12B mRNA] CTD PMID:19159680 lithium hydride multiple interactions ISO RGD:732857 6480464 Lithium inhibits the reaction [Lipopolysaccharides results in increased expression of IL12B mRNA] CTD PMID:19159680 lupane multiple interactions ISO RGD:1353629 6480464 lupane results in increased secretion of [IL12A protein binds to IL12B protein] CTD PMID:16388738 luteolin multiple interactions ISO RGD:732857 6480464 Luteolin inhibits the reaction [Lipopolysaccharides results in increased expression of IL12B mRNA], Luteolin inhibits the reaction [Poly I-C results in increased expression of IL12B mRNA] CTD PMID:19426678 manganese(II) chloride multiple interactions ISO RGD:1353629 6480464 manganese chloride promotes the reaction [SNCA protein results in increased expression of [IL12A protein binds to IL12B protein]] CTD PMID:28539244 manganese(II) chloride increases expression ISO RGD:732857 6480464 manganese chloride results in increased expression of IL12B mRNA CTD PMID:28539244 manganese(II) chloride multiple interactions ISO RGD:732857 6480464 manganese chloride results in increased expression of [IL12A protein binds to IL12B protein] CTD PMID:28539244 mangiferin multiple interactions EXP 6480464 mangiferin inhibits the reaction [Galactosamine results in increased expression of IL12B mRNA] CTD PMID:22310181 mechlorethamine multiple interactions EXP 6480464 Valproic Acid inhibits the reaction [Mechlorethamine results in increased expression of IL12B mRNA] CTD PMID:28184907 mechlorethamine increases expression EXP 6480464 Mechlorethamine results in increased expression of IL12B mRNA CTD PMID:28184907 medroxyprogesterone acetate multiple interactions ISO RGD:1353629 6480464 [Estradiol co-treated with Bucladesine co-treated with Medroxyprogesterone Acetate] results in increased expression of IL12B mRNA CTD PMID:20823114 mercury dichloride multiple interactions ISO RGD:732857 6480464 Mercuric Chloride results in increased expression of [IL12A protein binds to IL12B protein] CTD PMID:21984480 mercury dichloride decreases expression ISO RGD:732857 6480464 Mercuric Chloride results in decreased expression of IL12B protein CTD PMID:21984480 metam multiple interactions ISO RGD:732857 6480464 [Nadolol co-treated with Mifepristone] inhibits the reaction [methyldithiocarbamate inhibits the reaction [Lipopolysaccharides results in increased secretion of IL12B protein]] more ... CTD PMID:15933225 more ... methapyrilene increases expression EXP 6480464 Methapyrilene results in increased expression of IL12B protein CTD PMID:25051504 methoxychlor increases expression ISO RGD:732857 6480464 Methoxychlor results in increased expression of IL12B mRNA CTD PMID:22842586 methyl 3,4,5-trihydroxybenzoate multiple interactions ISO RGD:732857 6480464 methyl gallate results in increased expression of [IL12A protein binds to IL12B protein] CTD PMID:32112863 methyl isothiocyanate multiple interactions ISO RGD:732857 6480464 methyl isothiocyanate inhibits the reaction [Lipopolysaccharides results in increased expression of IL12B mRNA] CTD PMID:15933225 methylprednisolone aceponate multiple interactions ISO RGD:1353629 6480464 methylprednisolone aceponate inhibits the reaction [endotoxin, Escherichia coli results in increased secretion of IL12B protein] CTD PMID:19422381 mifepristone multiple interactions ISO RGD:732857 6480464 [Nadolol co-treated with Mifepristone] inhibits the reaction [methyldithiocarbamate inhibits the reaction [Lipopolysaccharides results in increased secretion of IL12B protein]] CTD PMID:16321413 mifepristone multiple interactions ISO RGD:1353629 6480464 Mifepristone inhibits the reaction [R-1 more ... CTD PMID:19422381 mometasone furoate multiple interactions ISO RGD:1353629 6480464 Mometasone Furoate inhibits the reaction [endotoxin, Escherichia coli results in increased secretion of IL12B protein] CTD PMID:19422381 monodansylcadaverine multiple interactions ISO RGD:732857 6480464 monodansylcadaverine promotes the reaction [lipopolysaccharide, Escherichia coli O111 B4 results in increased secretion of IL12B protein] CTD PMID:22341560 montelukast multiple interactions ISO RGD:1353629 6480464 montelukast inhibits the reaction [Leukotriene D4 results in increased secretion of [IL12A protein binds to IL12B protein]] CTD PMID:19118273 morphine affects expression ISO RGD:732857 6480464 Morphine affects the expression of IL12B protein CTD PMID:16299287 morphine multiple interactions ISO RGD:732857 6480464 Morphine affects the expression of [IL12A protein binds to IL12B protein] CTD PMID:16299287 muramyl dipeptide increases secretion ISO RGD:1353629 6480464 Acetylmuramyl-Alanyl-Isoglutamine analog results in increased secretion of IL12B protein CTD PMID:15905553 muramyl dipeptide multiple interactions ISO RGD:732857 6480464 Acetylmuramyl-Alanyl-Isoglutamine promotes the reaction [Lipopolysaccharides results in increased expression of IL12B protein] CTD PMID:19897531 muramyl dipeptide increases secretion ISO RGD:732857 6480464 Acetylmuramyl-Alanyl-Isoglutamine analog results in increased secretion of IL12B protein CTD PMID:15905553 muramyl dipeptide multiple interactions ISO RGD:1353629 6480464 [Acetylmuramyl-Alanyl-Isoglutamine co-treated with Lipid A] results in increased expression of [IL12A protein binds to IL12B protein] more ... CTD PMID:16299289 , PMID:18490488 N-acetyl-L-cysteine multiple interactions ISO RGD:732857 6480464 Acetylcysteine inhibits the reaction [Nicotine results in increased expression of IL12B mRNA], Acetylcysteine inhibits the reaction [Nicotine results in increased secretion of [IL12A protein co-treated with IL12B protein]] CTD PMID:21237301 N-nitrosodiethylamine increases expression EXP 6480464 Diethylnitrosamine results in increased expression of IL12B protein CTD PMID:25051504 N-nitrosodimethylamine multiple interactions EXP 6480464 Zinc Oxide inhibits the reaction [Dimethylnitrosamine results in increased expression of IL12B protein] CTD PMID:29024620 N-nitrosodimethylamine increases expression EXP 6480464 Dimethylnitrosamine results in increased expression of IL12B protein CTD PMID:29024620 N1'-[2-[[5-[(dimethylamino)methyl]-2-furanyl]methylthio]ethyl]-N1-methyl-2-nitroethene-1,1-diamine multiple interactions ISO RGD:1353629 6480464 Ranitidine inhibits the reaction [Histamine inhibits the reaction [IL18 protein results in increased expression of [IL12A protein binds to IL12B protein]]], Ranitidine inhibits the reaction [Histamine results in decreased expression of IL12B protein] CTD PMID:11752121 , PMID:9819373 nadolol multiple interactions ISO RGD:732857 6480464 [Nadolol co-treated with Mifepristone] inhibits the reaction [methyldithiocarbamate inhibits the reaction [Lipopolysaccharides results in increased secretion of IL12B protein]] CTD PMID:16321413 nickel atom increases expression ISO RGD:1353629 6480464 Nickel results in increased expression of IL12B mRNA CTD PMID:24768652 nickel sulfate affects expression ISO RGD:1353629 6480464 nickel sulfate affects the expression of IL12B mRNA CTD PMID:18202158 nickel sulfate increases expression ISO RGD:1353629 6480464 nickel sulfate results in increased expression of IL12B mRNA, nickel sulfate results in increased expression of IL12B protein CTD PMID:25673294 , PMID:30421605 nickel sulfate increases secretion ISO RGD:1353629 6480464 nickel sulfate results in increased secretion of IL12B protein CTD PMID:17636246 more ... nickel sulfate multiple interactions ISO RGD:1353629 6480464 2-(2-amino-3-methoxyphenyl)-4H-1-benzopyran-4-one promotes the reaction [nickel sulfate results in increased secretion of IL12B protein] more ... CTD PMID:17636246 more ... nicotine multiple interactions ISO RGD:732857 6480464 Acetylcysteine inhibits the reaction [Nicotine results in increased expression of IL12B mRNA] more ... CTD PMID:21237301 nicotine increases expression ISO RGD:732857 6480464 Nicotine results in increased expression of IL12B mRNA CTD PMID:21237301 nitric oxide decreases expression ISO RGD:1353629 6480464 Nitric Oxide results in decreased expression of IL12B protein CTD PMID:13678430 nonanoic acid increases expression ISO RGD:732857 6480464 pelargonic acid results in increased expression of IL12B mRNA, pelargonic acid results in increased expression of IL12B protein CTD PMID:11379042 , PMID:18652873 nonanoic acid affects expression ISO RGD:732857 6480464 pelargonic acid affects the expression of IL12B mRNA CTD PMID:22302311 ochratoxin A multiple interactions ISO RGD:732857 6480464 [Lipopolysaccharides co-treated with ochratoxin A] results in increased expression of IL12B protein CTD PMID:28935500 ozone multiple interactions ISO RGD:732857 6480464 [LEP gene mutant form results in increased susceptibility to Ozone] which results in increased expression of IL12B protein, [Ozone co-treated with Lipopolysaccharides] results in increased expression of IL12B protein CTD PMID:18929643 , PMID:27472835 ozone decreases expression ISO RGD:732857 6480464 Ozone results in decreased expression of IL12B protein CTD PMID:28533327 ozone multiple interactions ISO RGD:1353629 6480464 [Vehicle Emissions co-treated with Ozone] results in decreased expression of [IL12A protein binds to IL12B protein] CTD PMID:27058360 paclitaxel multiple interactions ISO RGD:732857 6480464 CD14 protein affects the reaction [Paclitaxel results in increased expression of IL12B mRNA] more ... CTD PMID:11123339 paclitaxel increases expression ISO RGD:732857 6480464 Paclitaxel results in increased expression of IL12B mRNA CTD PMID:11123339 paracetamol increases expression ISO RGD:732857 6480464 Acetaminophen results in increased expression of IL12B mRNA, Acetaminophen results in increased expression of IL12B protein CTD PMID:22575169 , PMID:29246445 paracetamol multiple interactions ISO RGD:732857 6480464 MST1R protein affects the reaction [Acetaminophen results in increased expression of IL12B mRNA] CTD PMID:22575169 parathion multiple interactions ISO RGD:732857 6480464 [Parathion co-treated with Antigens, Dermatophagoides] affects the expression of IL12B protein CTD PMID:21864637 parathion increases expression ISO RGD:732857 6480464 Parathion results in increased expression of IL12B mRNA CTD PMID:22842586 parthenolide decreases expression ISO RGD:1353629 6480464 parthenolide results in decreased expression of IL12B mRNA CTD PMID:16921510 peptidoglycan increases expression ISO RGD:1353629 6480464 Peptidoglycan results in increased expression of IL12B mRNA CTD PMID:15860229 perfluorooctanoic acid increases expression EXP 6480464 perfluorooctanoic acid results in increased expression of IL12B mRNA CTD PMID:19162173 phenanthridone multiple interactions ISO RGD:1353629 6480464 phenanthridone inhibits the reaction [Lipopolysaccharides results in increased secretion of IL12B protein] CTD PMID:17579050 phenethyl caffeate multiple interactions ISO RGD:732857 6480464 caffeic acid phenethyl ester inhibits the reaction [AIMP1 protein results in increased expression of IL12B mRNA] CTD PMID:16365417 phenylarsine oxide multiple interactions ISO RGD:732857 6480464 Colforsin inhibits the reaction [oxophenylarsine promotes the reaction [Lipopolysaccharides results in increased expression of IL12B protein]] more ... CTD PMID:20512473 phorbol 12,13-dibutanoate increases expression ISO RGD:1353629 6480464 Phorbol 12, 13-Dibutyrate results in increased expression of IL12B mRNA CTD PMID:15516327 phorbol 13-acetate 12-myristate increases expression ISO RGD:1353629 6480464 Tetradecanoylphorbol Acetate results in increased expression of IL12B mRNA CTD PMID:15614042 phthalaldehyde affects expression ISO RGD:732857 6480464 o-Phthalaldehyde affects the expression of IL12B mRNA CTD PMID:22302311 pirinixic acid multiple interactions ISO RGD:732857 6480464 [Picryl Chloride co-treated with pirinixic acid] results in decreased expression of IL12B protein more ... CTD PMID:15968640 , PMID:17371993 pirinixic acid decreases expression ISO RGD:732857 6480464 pirinixic acid results in decreased expression of IL12B protein CTD PMID:20131406 pirinixic acid increases expression EXP 6480464 pirinixic acid results in increased expression of IL12B mRNA CTD PMID:19162173 poly(I:C) multiple interactions ISO RGD:1353629 6480464 [[Poly I-C binds to and results in increased activity of TLR3 protein] which co-treated with Nanotubes, Carbon] results in increased secretion of IL12B protein more ... CTD PMID:16890772 , PMID:23266719 poly(I:C) increases expression ISO RGD:1353629 6480464 Poly I-C results in increased expression of IL12B protein CTD PMID:16890772 poly(I:C) increases expression ISO RGD:732857 6480464 Poly I-C results in increased expression of IL12B mRNA, Poly I-C results in increased expression of IL12B protein CTD PMID:19426678 , PMID:19500611 poly(I:C) multiple interactions ISO RGD:732857 6480464 Ethanol inhibits the reaction [Poly I-C results in increased expression of IL12B protein], Luteolin inhibits the reaction [Poly I-C results in increased expression of IL12B mRNA] CTD PMID:19426678 , PMID:19500611 polymyxin B2 multiple interactions ISO RGD:732857 6480464 Polymyxin B inhibits the reaction [[Ovalbumin co-treated with Dust] results in increased expression of [IL12A protein binds to IL12B protein]], Polymyxin B inhibits the reaction [Lipopolysaccharides results in increased secretion of IL12B protein] CTD PMID:26882889 , PMID:9278343 prednisolone decreases secretion ISO RGD:732857 6480464 Prednisolone results in decreased secretion of IL12B protein CTD PMID:28003376 prednisone multiple interactions ISO RGD:1353629 6480464 Prednisone results in increased expression of [IL12A protein binds to IL12B protein] CTD PMID:19584951 procyanidin B3 multiple interactions ISO RGD:732857 6480464 procyanidin B3 inhibits the reaction [Lipopolysaccharides results in increased expression of IL12B mRNA] CTD PMID:22169119 progesterone multiple interactions ISO RGD:1353629 6480464 [Progesterone co-treated with Estradiol] inhibits the reaction [Vaccines, Virus-Like Particle results in increased expression of [IL12A protein binds to IL12B protein]] more ... CTD PMID:20130130 progesterone multiple interactions ISO RGD:732857 6480464 Progesterone inhibits the reaction [[Lipopolysaccharides co-treated with IL4 protein] results in increased expression of IL12B mRNA], Progesterone inhibits the reaction [Lipopolysaccharides results in increased expression of IL12B mRNA] CTD PMID:21977998 prostaglandin E2 multiple interactions ISO RGD:1353629 6480464 [TNF protein co-treated with IL1B protein co-treated with Dinoprostone] results in increased expression of IL12B protein more ... CTD PMID:10614771 , PMID:11369638 prostaglandin E2 increases expression ISO RGD:732857 6480464 Dinoprostone results in increased expression of IL12B protein CTD PMID:15180965 prostaglandin E2 multiple interactions ISO RGD:732857 6480464 CSF2 protein promotes the reaction [Dinoprostone results in increased expression of [IL12B protein binds to IL23A protein]], Dinoprostone results in increased expression of [IL12B protein binds to IL23A protein] CTD PMID:15180965 prostaglandin E2 increases secretion ISO RGD:1353629 6480464 Dinoprostone results in increased secretion of IL12B protein CTD PMID:11369638 prostaglandin E2 increases expression ISO RGD:1353629 6480464 Dinoprostone results in increased expression of IL12B mRNA, Dinoprostone results in increased expression of IL12B protein CTD PMID:11369638 , PMID:16303787 protein kinase inhibitor decreases secretion ISO RGD:732857 6480464 Protein Kinase Inhibitors results in decreased secretion of IL12B protein CTD PMID:28003376 protein kinase inhibitor multiple interactions ISO RGD:1353629 6480464 Protein Kinase Inhibitors inhibits the reaction [gardiquimod results in increased expression of IL12B mRNA] CTD PMID:28003376 pyrrolidine dithiocarbamate multiple interactions ISO RGD:732857 6480464 pyrrolidine dithiocarbamic acid inhibits the reaction [Lipopolysaccharides results in increased secretion of IL12B protein] CTD PMID:15778123 quercetin decreases expression ISO RGD:732857 6480464 Quercetin results in decreased expression of IL12B mRNA CTD PMID:22185406 quercetin multiple interactions ISO RGD:732857 6480464 Quercetin inhibits the reaction [Lipopolysaccharides results in increased expression of IL12B mRNA] CTD PMID:22185406 ranitidine multiple interactions ISO RGD:1353629 6480464 Ranitidine inhibits the reaction [Histamine inhibits the reaction [IL18 protein results in increased expression of [IL12A protein binds to IL12B protein]]], Ranitidine inhibits the reaction [Histamine results in decreased expression of IL12B protein] CTD PMID:11752121 , PMID:9819373 resiquimod multiple interactions ISO RGD:1353629 6480464 [Acetylmuramyl-Alanyl-Isoglutamine co-treated with resiquimod co-treated with IFNG protein] results in increased expression of [IL12A protein binds to IL12B protein] more ... CTD PMID:18490488 resiquimod increases expression ISO RGD:732857 6480464 resiquimod results in increased expression of IL12B protein CTD PMID:15187114 resiquimod multiple interactions ISO RGD:732857 6480464 [resiquimod co-treated with Lipopolysaccharides] results in increased secretion of [IL12A protein binds to IL12B protein], Simvastatin promotes the reaction [resiquimod results in increased expression of IL12B protein] CTD PMID:15187114 , PMID:15851485 resiquimod increases expression ISO RGD:1353629 6480464 resiquimod results in increased expression of IL12B protein CTD PMID:18490488 resveratrol multiple interactions ISO RGD:732857 6480464 resveratrol inhibits the reaction [Lipopolysaccharides results in increased expression of IL12B protein] CTD PMID:14996416 resveratrol multiple interactions ISO RGD:1353629 6480464 resveratrol inhibits the reaction [Oxygen deficiency results in increased expression of IL12B mRNA] more ... CTD PMID:15135313 , PMID:23452621 ribavirin multiple interactions ISO RGD:1353629 6480464 [Ribavirin co-treated with IFNA2 protein] promotes the reaction [Lipopolysaccharides results in increased secretion of [IL12A protein binds to IL12B protein]], Ribavirin promotes the reaction [Lipopolysaccharides results in increased secretion of [IL12A protein binds to IL12B protein]] CTD PMID:9722937 Ro 41-5253 multiple interactions ISO RGD:1353629 6480464 Ro 41-5253 inhibits the reaction [Tretinoin results in decreased secretion of [IL12A protein binds to IL12B protein]] CTD PMID:16872382 rotenone increases expression ISO RGD:1353629 6480464 Rotenone results in increased expression of IL12B mRNA CTD PMID:29955902 rottlerin multiple interactions ISO RGD:732857 6480464 rottlerin promotes the reaction [Lipopolysaccharides results in increased secretion of IL12B protein] CTD PMID:16330529 S-butyl-DL-homocysteine (S,R)-sulfoximine multiple interactions ISO RGD:732857 6480464 Buthionine Sulfoximine inhibits the reaction [Lipopolysaccharides results in increased expression of IL12B protein], Buthionine Sulfoximine inhibits the reaction [methyldithiocarbamate inhibits the reaction [Lipopolysaccharides results in increased secretion of IL12B protein]] CTD PMID:12688424 , PMID:19339665 S-nitrosoglutathione decreases expression ISO RGD:1353629 6480464 S-Nitrosoglutathione results in decreased expression of IL12B protein CTD PMID:13678430 SB 203580 multiple interactions ISO RGD:732857 6480464 SB 203580 inhibits the reaction [Lipopolysaccharides results in increased expression of IL12B mRNA], SB 203580 inhibits the reaction [Lipopolysaccharides results in increased secretion of IL12B protein] CTD PMID:11006016 , PMID:15778123 SB 203580 multiple interactions ISO RGD:1353629 6480464 SB 203580 inhibits the reaction [[IL12A protein binds to IL12B protein] which results in increased expression of IFNG protein] more ... CTD PMID:10952721 more ... serotonin affects secretion ISO RGD:1353629 6480464 Serotonin affects the secretion of IL12B protein CTD PMID:15802305 serpentine asbestos increases expression ISO RGD:732857 6480464 Asbestos, Serpentine results in increased expression of IL12B protein CTD PMID:17200189 more ... serpentine asbestos multiple interactions ISO RGD:732857 6480464 PRKDC affects the reaction [Asbestos, Serpentine results in increased expression of IL12B protein], SPP1 gene mutant form inhibits the reaction [Asbestos, Serpentine results in increased expression of IL12B protein] CTD PMID:17200189 , PMID:21514415 silicon dioxide multiple interactions ISO RGD:732857 6480464 IL12A gene mutant form promotes the reaction [Silicon Dioxide results in increased expression of and results in increased secretion of IL12B protein], Silicon Dioxide results in increased expression of and results in increased secretion of IL12B protein CTD PMID:12193738 silicon dioxide increases expression ISO RGD:732857 6480464 Silicon Dioxide results in increased expression of IL12B mRNA CTD PMID:29341224 silicon dioxide affects response to substance ISO RGD:732857 6480464 IL12B protein affects the susceptibility to Silicon Dioxide CTD PMID:12193738 silicon dioxide decreases response to substance ISO RGD:732857 6480464 IL12B gene mutant form results in decreased susceptibility to Silicon Dioxide CTD PMID:12193738 simvastatin multiple interactions ISO RGD:732857 6480464 FOS inhibits the reaction [Simvastatin results in increased expression of IL12B mRNA] more ... CTD PMID:15187114 simvastatin increases expression ISO RGD:732857 6480464 Simvastatin results in increased expression of IL12B mRNA CTD PMID:15187114 sirolimus multiple interactions ISO RGD:732857 6480464 Sirolimus inhibits the reaction [IL4 protein results in increased expression of [IL12A protein binds to IL12B protein]] CTD PMID:12531798 sodium arsenite increases expression ISO RGD:1353629 6480464 sodium arsenite results in increased expression of IL12B mRNA CTD PMID:12760830 sodium stibogluconate multiple interactions ISO RGD:732857 6480464 [IFNG protein co-treated with Antimony Sodium Gluconate] results in increased expression of IL12B mRNA CTD PMID:9234779 SR 144528 multiple interactions ISO RGD:732857 6480464 SR 144528 inhibits the reaction [1, 1-dimethylbutyl-1-deoxy-Delta(9)-THC inhibits the reaction [Lipopolysaccharides results in increased secretion of IL12B protein]] CTD PMID:15821753 streptozocin increases expression ISO RGD:732857 6480464 Streptozocin results in increased expression of IL12B mRNA CTD PMID:11357882 streptozocin multiple interactions ISO RGD:732857 6480464 Dronabinol inhibits the reaction [Streptozocin results in increased expression of IL12B mRNA] CTD PMID:11357882 sulfapyridine multiple interactions ISO RGD:732857 6480464 Sulfapyridine inhibits the reaction [[Lipopolysaccharides co-treated with IFNG protein] results in increased expression of IL12B protein] CTD PMID:11529938 sulfasalazine multiple interactions ISO RGD:732857 6480464 Sulfasalazine inhibits the reaction [[Lipopolysaccharides co-treated with IFNG protein] results in increased expression of [IL12B protein binds to IL12A protein]], Sulfasalazine inhibits the reaction [[Lipopolysaccharides co-treated with IFNG protein] results in increased expression of IL12B protein] CTD PMID:11529938 sulforaphane multiple interactions ISO RGD:1353629 6480464 NFE2L2 protein affects the reaction [sulforafan inhibits the reaction [Lipopolysaccharides results in increased expression of IL12B protein]], sulforafan inhibits the reaction [Lipopolysaccharides results in increased expression of IL12B protein] CTD PMID:16890772 suramin increases expression ISO RGD:1353629 6480464 Suramin results in increased expression of IL12B protein CTD PMID:15914193 thalidomide multiple interactions ISO RGD:1353629 6480464 Thalidomide results in decreased expression of [IL12A protein binds to IL12B protein] CTD PMID:11788559 thalidomide multiple interactions ISO RGD:732857 6480464 Thalidomide inhibits the reaction [SOD1 gene mutant form results in increased expression of IL12B mRNA] CTD PMID:16510725 theophylline multiple interactions ISO RGD:1353629 6480464 Theophylline results in decreased expression of [IL12A protein binds to IL12B protein] CTD PMID:15569413 theophylline decreases expression ISO RGD:1353629 6480464 Theophylline results in decreased expression of IL12B protein CTD PMID:15569413 titanium dioxide increases expression ISO RGD:732857 6480464 titanium dioxide results in increased expression of IL12B protein CTD PMID:23557971 toluene 2,4-diisocyanate increases expression ISO RGD:732857 6480464 Toluene 2 more ... CTD PMID:11379042 , PMID:18652873 trichostatin A multiple interactions ISO RGD:1353629 6480464 trichostatin A inhibits the reaction [Lipopolysaccharides results in increased expression of IL12B mRNA] CTD PMID:12470611 trifluoperazine multiple interactions ISO RGD:732857 6480464 Trifluoperazine inhibits the reaction [Hydrogen Peroxide results in decreased expression of IL12B protein] CTD PMID:16249388 trimellitic acid increases methylation ISO RGD:732857 6480464 trimellitic acid results in increased methylation of IL12B gene CTD PMID:26732893 trimellitic acid decreases methylation ISO RGD:732857 6480464 trimellitic acid results in decreased methylation of IL12B gene CTD PMID:26732893 trimellitic anhydride affects expression ISO RGD:732857 6480464 trimellitic anhydride affects the expression of IL12B mRNA CTD PMID:22302311 Triptolide multiple interactions ISO RGD:1353629 6480464 triptolide inhibits the reaction [[Lipopolysaccharides co-treated with IFNG protein] results in increased expression of [IL12A protein binds to IL12B protein]], triptolide inhibits the reaction [[Lipopolysaccharides co-treated with IFNG protein] results in increased expression of IL12B protein] CTD PMID:15663903 tunicamycin multiple interactions ISO RGD:1353629 6480464 Tunicamycin inhibits the reaction [IL12A protein binds to IL12B protein], Tunicamycin results in decreased secretion of [IL12A protein binds to IL12B protein] CTD PMID:10779781 urethane multiple interactions ISO RGD:732857 6480464 Freund's Adjuvant promotes the reaction [Urethane results in decreased expression of IL12B mRNA] CTD PMID:12810352 valproic acid multiple interactions EXP 6480464 Valproic Acid inhibits the reaction [Mechlorethamine results in increased expression of IL12B mRNA] CTD PMID:28184907 valproic acid increases expression ISO RGD:1353629 6480464 Valproic Acid results in increased expression of IL12B mRNA CTD PMID:25091725 warfarin increases expression EXP 6480464 Warfarin results in increased expression of IL12B mRNA CTD PMID:22342526 wortmannin multiple interactions ISO RGD:1353629 6480464 wortmannin inhibits the reaction [C5 protein results in decreased expression of [IL12A protein binds to IL12B protein]] more ... CTD PMID:16116186 zileuton multiple interactions ISO RGD:1353629 6480464 zileuton inhibits the reaction [Leukotriene D4 results in increased secretion of [IL12A protein binds to IL12B protein]] CTD PMID:19118273 zinc dichloride decreases expression ISO RGD:732857 6480464 zinc chloride results in decreased expression of IL12B mRNA CTD PMID:24284788 zinc oxide multiple interactions EXP 6480464 Zinc Oxide inhibits the reaction [Dimethylnitrosamine results in increased expression of IL12B protein] CTD PMID:29024620
Gene-Chemical Interaction Annotations
