Nf1 (neurofibromin 1) - Rat Genome Database

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Gene: Nf1 (neurofibromin 1) Rattus norvegicus
Analyze
Symbol: Nf1
Name: neurofibromin 1
RGD ID: 3168
Description: Enables microtubule binding activity and syndecan binding activity. Involved in several processes, including Schwann cell differentiation; cellular response to dexamethasone stimulus; and cellular response to nerve growth factor stimulus. Located in several cellular components, including axon; dendrite; and postsynaptic density. Part of protein-containing complex. Biomarker of sciatic neuropathy and transient cerebral ischemia. Human ortholog(s) of this gene implicated in autistic disorder; hematologic cancer (multiple); nervous system cancer (multiple); neurofibromatosis 1; and neurofibromatosis-Noonan syndrome. Orthologous to human NF1 (neurofibromin 1); PARTICIPATES IN forkhead class A signaling pathway; syndecan signaling pathway; mitogen activated protein kinase signaling pathway; INTERACTS WITH 17alpha-ethynylestradiol; 2,3,7,8-tetrachlorodibenzodioxine; 2,3,7,8-Tetrachlorodibenzofuran.
Type: protein-coding
RefSeq Status: PROVISIONAL
Previously known as: neurofibromatosis 1; Neurofibromatosis type 1; neurofibromatosis-related protein NF-1; neurofibromin
RGD Orthologs
Human
Mouse
Chinchilla
Bonobo
Dog
Squirrel
Pig
Green Monkey
Naked Mole-Rat
Alliance Genes
More Info more info ...
Latest Assembly: mRatBN7.2 - mRatBN7.2 Assembly
Position:
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
mRatBN7.21064,306,027 - 64,539,112 (+)NCBImRatBN7.2
mRatBN7.2 Ensembl1064,306,301 - 64,536,658 (+)Ensembl
Rnor_6.01066,732,460 - 66,928,706 (+)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl1066,690,133 - 66,928,903 (+)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.01064,826,693 - 64,916,699 (-)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
Rnor_5.01064,719,521 - 64,758,677 (-)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.41065,574,833 - 65,766,305 (+)NCBIRGSC3.4rn4RGSC3.4
RGSC_v3.11065,545,464 - 65,779,928 (+)NCBI
Celera1063,277,856 - 63,507,181 (+)NCBICelera
Cytogenetic Map10q25NCBI
JBrowse: View Region in Genome Browser (JBrowse)
Model


Disease Annotations     Click to see Annotation Detail View
acute monocytic leukemia  (ISO)
acute myeloid leukemia  (ISO)
adenoma  (ISO)
Aortic Coarctation  (ISO)
autism spectrum disorder  (ISO)
autistic disorder  (ISO)
B-cell acute lymphoblastic leukemia  (ISO)
Cafe au lait Spots, Multiple  (ISO)
Cafe-au-Lait Spots  (ISO)
centronuclear myopathy 5  (ISO)
cerebral palsy  (ISO)
colon cancer  (ISO)
colorectal carcinoma  (ISO)
craniopharyngioma  (ISO)
Developmental Disabilities  (ISO)
diffuse midline glioma, H3 K27M-mutant  (ISO)
Ewing sarcoma  (ISO)
Febrile Seizures  (ISO)
Femoral Fractures  (ISO)
fibrosarcoma  (ISO)
ganglioglioma  (ISO)
genetic disease  (ISO)
glioblastoma  (ISO)
hereditary breast ovarian cancer syndrome  (ISO)
Hereditary Neoplastic Syndromes  (ISO)
high grade glioma  (ISO)
inguinal hernia  (ISO)
intellectual disability  (ISO)
juvenile myelomonocytic leukemia  (ISO)
keratoconus  (ISO)
learning disability  (ISO)
liposarcoma  (ISO)
lung non-small cell carcinoma  (ISO)
malignant astrocytoma  (ISO)
melanoma  (ISO)
microcephaly  (ISO)
multiple myeloma  (ISO)
Nerve Sheath Neoplasms  (ISO)
neurilemmoma  (ISO)
neurofibroma  (ISO)
neurofibromatosis  (ISO)
neurofibromatosis 1  (ISO)
Neurofibromatosis, Familial Spinal  (ISO)
neurofibromatosis-Noonan syndrome  (ISO)
optic nerve glioma  (ISO)
pheochromocytoma  (ISO)
Pigmented Nevus  (ISO)
pilocytic astrocytoma  (ISO)
plexiform neurofibroma  (ISO)
Pseudarthrosis  (IEP)
RASopathy  (ISO)
Retinal Neovascularization  (ISO)
retinoblastoma  (ISO)
rhabdomyosarcoma  (ISO)
sarcoma  (ISO)
sciatic neuropathy  (IEP)
strabismus  (ISO)
transient cerebral ischemia  (IEP)
Tumor Predisposition Syndrome  (ISO)
Wallerian Degeneration  (IEP)
Watson Syndrome  (ISO)

Gene-Chemical Interaction Annotations     Click to see Annotation Detail View
(-)-epigallocatechin 3-gallate  (ISO)
1,2-dimethylhydrazine  (ISO)
17alpha-ethynylestradiol  (EXP)
17beta-estradiol  (ISO)
2,2',4,4'-Tetrabromodiphenyl ether  (ISO)
2,3,7,8-tetrachlorodibenzodioxine  (EXP,ISO)
2,3,7,8-Tetrachlorodibenzofuran  (EXP)
2,4,6-tribromophenol  (ISO)
3,3',5,5'-tetrabromobisphenol A  (ISO)
3,4-methylenedioxymethamphetamine  (ISO)
3-Nitrobenzanthrone  (ISO)
4,4'-sulfonyldiphenol  (ISO)
acrylamide  (EXP)
afimoxifene  (ISO)
all-trans-retinoic acid  (ISO)
androgen antagonist  (EXP)
antirheumatic drug  (ISO)
aristolochic acid  (ISO)
arsane  (ISO)
arsenic atom  (ISO)
arsenite(3-)  (ISO)
aspartame  (ISO)
benzo[a]pyrene  (ISO)
benzo[a]pyrene diol epoxide I  (ISO)
bis(2-chloroethyl) sulfide  (ISO)
bis(2-ethylhexyl) phthalate  (EXP)
bisphenol A  (EXP,ISO)
butanal  (ISO)
Butylparaben  (EXP)
cadmium dichloride  (ISO)
calcium atom  (ISO)
calcium(0)  (ISO)
carbon nanotube  (ISO)
chlordecone  (ISO)
choline  (ISO)
cobalt dichloride  (ISO)
cocaine  (EXP)
copper atom  (ISO)
copper(0)  (ISO)
crocidolite asbestos  (ISO)
cyclosporin A  (ISO)
DDE  (EXP)
decabromodiphenyl ether  (ISO)
dibutyl phthalate  (EXP)
dioxygen  (ISO)
disodium selenite  (ISO)
dorsomorphin  (ISO)
entinostat  (ISO)
enzacamene  (EXP)
epoxiconazole  (EXP)
fluoxetine  (ISO)
folic acid  (ISO)
fulvestrant  (ISO)
gallic acid  (ISO)
geldanamycin  (ISO)
hexadecanoic acid  (ISO)
hydralazine  (ISO)
ivermectin  (ISO)
L-methionine  (ISO)
lead diacetate  (ISO)
linsidomine  (EXP)
linuron  (EXP)
mercury dibromide  (ISO)
methylmercury chloride  (ISO)
methylmercury(1+)  (ISO)
monosodium L-glutamate  (ISO)
motexafin gadolinium  (ISO)
nickel atom  (ISO)
ochratoxin A  (ISO)
p-chloromercuribenzoic acid  (ISO)
panobinostat  (ISO)
paracetamol  (EXP,ISO)
paraquat  (EXP)
PD 0325901  (ISO)
phenylmercury acetate  (ISO)
potassium chromate  (ISO)
prochloraz  (EXP)
procymidone  (EXP)
raloxifene  (ISO)
SB 431542  (ISO)
silicon dioxide  (ISO)
sodium arsenite  (ISO)
thimerosal  (ISO)
tributylstannane  (ISO)
Tributyltin oxide  (ISO)
trichostatin A  (ISO)
triptonide  (ISO)
valproic acid  (ISO)
vinclozolin  (EXP)
vorinostat  (ISO)
zinc acetate  (ISO)
zinc atom  (ISO)
zinc(0)  (ISO)

Gene Ontology Annotations     Click to see Annotation Detail View

Biological Process
actin cytoskeleton organization  (IEA,ISO,ISS)
adrenal gland development  (IEA,ISO,ISS)
amygdala development  (IEA,ISO)
angiogenesis  (IEA,ISO)
apoptotic process  (ISO)
artery morphogenesis  (IEA,ISO,ISS)
astrocyte differentiation  (ISO)
brain development  (ISO,ISS)
camera-type eye morphogenesis  (IEA,ISO,ISS)
cell communication  (ISO,ISS)
cell migration  (ISO)
cell population proliferation  (ISO)
cellular response to dexamethasone stimulus  (IEP)
cellular response to heat  (IEA,ISO)
cellular response to nerve growth factor stimulus  (IEP)
cerebral cortex development  (IEA,ISO,ISS)
cognition  (ISO)
collagen fibril organization  (IEA,ISO,ISS)
endothelial cell proliferation  (IEA,ISO)
extracellular matrix organization  (ISO,ISS)
extrinsic apoptotic signaling pathway in absence of ligand  (IEA,ISO)
extrinsic apoptotic signaling pathway via death domain receptors  (IEA,ISO)
fibroblast proliferation  (IEA,ISO)
forebrain astrocyte development  (IEA,ISO,ISS)
forebrain morphogenesis  (IEA,ISO,ISS)
gamma-aminobutyric acid secretion, neurotransmission  (IEA,ISO)
glial cell proliferation  (ISO)
glutamate secretion, neurotransmission  (IEA,ISO)
hair follicle maturation  (IEA,ISO)
heart development  (IEA,ISO,ISS)
leukocyte apoptotic process  (ISO)
liver development  (IEA,ISO,ISS)
MAPK cascade  (IEA,ISO,ISS)
mast cell apoptotic process  (IEA,ISO)
mast cell proliferation  (IEA,ISO)
metanephros development  (IEA,ISO,ISS)
myelination in peripheral nervous system  (IEA,ISO,ISS)
myeloid cell apoptotic process  (ISO)
myeloid leukocyte migration  (IEA,ISO)
negative regulation of angiogenesis  (IEA,ISO)
negative regulation of astrocyte differentiation  (IEA,ISO)
negative regulation of cell migration  (ISO)
negative regulation of cell population proliferation  (ISO)
negative regulation of cell-matrix adhesion  (IEA,ISO)
negative regulation of endothelial cell proliferation  (IEA,ISO)
negative regulation of fibroblast proliferation  (IEA,ISO,ISS)
negative regulation of glial cell proliferation  (ISO)
negative regulation of leukocyte migration  (IEA,ISO)
negative regulation of MAP kinase activity  (IEA,ISO,ISS)
negative regulation of MAPK cascade  (ISO,ISS)
negative regulation of mast cell proliferation  (IEA,ISO)
negative regulation of neuroblast proliferation  (IEA,ISO,ISS)
negative regulation of neurotransmitter secretion  (IEA,ISO)
negative regulation of oligodendrocyte differentiation  (IEA,ISO,ISS)
negative regulation of osteoclast differentiation  (IEA,ISO)
negative regulation of protein import into nucleus  (IEA,ISO)
negative regulation of protein kinase activity  (ISO,ISS)
negative regulation of Rac protein signal transduction  (IEA,ISO)
negative regulation of Ras protein signal transduction  (ISO)
negative regulation of Schwann cell migration  (IEA,ISO)
negative regulation of Schwann cell proliferation  (IEA,ISO)
negative regulation of stem cell proliferation  (IEA,ISO)
negative regulation of vascular associated smooth muscle cell migration  (IEA,ISO)
neural tube development  (IEA,ISO)
neuroblast proliferation  (IEA,ISO)
neuron apoptotic process  (IEA,ISO)
neurotransmitter secretion  (ISO)
observational learning  (IEA,ISO)
oligodendrocyte differentiation  (IEA,ISO)
osteoblast differentiation  (IEA,ISO,ISS)
osteoclast differentiation  (IEA,ISO)
peripheral nervous system development  (ISO,ISS)
phosphatidylinositol 3-kinase signaling  (IEA,ISO,ISS)
pigmentation  (IEA,ISO,ISS)
positive regulation of adenylate cyclase activity  (IEA,ISO,ISS)
positive regulation of apoptotic process  (ISO,ISS)
positive regulation of endothelial cell proliferation  (IEA,ISO)
positive regulation of extrinsic apoptotic signaling pathway in absence of ligand  (IEA,ISO)
positive regulation of GTPase activity  (IEA,ISO,ISS)
positive regulation of leukocyte apoptotic process  (ISO)
positive regulation of mast cell apoptotic process  (IEA,ISO)
positive regulation of myeloid cell apoptotic process  (ISO)
positive regulation of neuron apoptotic process  (IEA,ISO,ISS)
positive regulation of neuron projection development  (IMP)
positive regulation of vascular associated smooth muscle cell proliferation  (IEA,ISO)
protein import into nucleus  (IEA,ISO)
Rac protein signal transduction  (IEA,ISO)
Ras protein signal transduction  (ISO,ISS)
regulation of angiogenesis  (ISO,ISS)
regulation of blood vessel endothelial cell migration  (ISO)
regulation of bone resorption  (IEA,ISO,ISS)
regulation of cell population proliferation  (ISO)
regulation of cell-matrix adhesion  (ISO,ISS)
regulation of gene expression  (IEA,ISO)
regulation of glial cell differentiation  (ISO,ISS)
regulation of GTPase activity  (IEA,IMP,ISO)
regulation of long-term neuronal synaptic plasticity  (IEA,ISO)
regulation of long-term synaptic potentiation  (IEA,ISO)
regulation of MAPK cascade  (ISO)
regulation of neuron differentiation  (IMP)
regulation of synaptic transmission, GABAergic  (IEA,ISO)
response to hypoxia  (IEA,ISO,ISS)
Schwann cell development  (ISO,ISS)
Schwann cell differentiation  (IEP)
Schwann cell migration  (IEA,ISO)
Schwann cell proliferation  (IEA,ISO)
signal transduction  (IEA)
skeletal muscle tissue development  (IEA,ISO)
smooth muscle tissue development  (IEA,ISO,ISS)
spinal cord development  (IEA,ISO,ISS)
stem cell proliferation  (IEA,ISO)
sympathetic nervous system development  (IEA,ISO,ISS)
vascular associated smooth muscle cell migration  (IEA,ISO)
vascular associated smooth muscle cell proliferation  (IEA,ISO)
visual learning  (IEA,ISO,ISS)
wound healing  (IEA,ISO,ISS)

Cellular Component
axon  (IDA,ISO)
cytoplasm  (IDA,IEA,ISO)
dendrite  (IDA,ISO)
membrane  (IDA)
neuron projection  (IDA)
nucleolus  (IEA)
nucleus  (IDA)
postsynaptic density  (IDA)
presynapse  (IEA)
protein-containing complex  (IDA)

Molecular Function

Molecular Pathway Annotations     Click to see Annotation Detail View
References

References - curated
1. Basu TN, etal., Nature 1992 Apr 23;356(6371):713-5.
2. Bianchessi D, etal., Genes (Basel). 2020 Jun 19;11(6). pii: genes11060671. doi: 10.3390/genes11060671.
3. Boudry-Labis E, etal., Am J Hematol. 2013 Apr;88(4):306-11. doi: 10.1002/ajh.23403. Epub 2013 Mar 5.
4. Cacev T, etal., Gut. 2005 Aug;54(8):1129-35. doi: 10.1136/gut.2004.053348. Epub 2005 Apr 19.
5. Costa RM, etal., Nat Genet 2001 Apr;27(4):399-405.
6. Daston MM, etal., Neuron. 1992 Mar;8(3):415-28.
7. Elzagheid A, etal., Anticancer Res. 2016 Oct;36(10):5301-5306. doi: 10.21873/anticanres.11102.
8. Giordano MJ, etal., J Neurosci Res. 1996 Jan 15;43(2):246-53.
9. Gitler AD, etal., Nat Genet 2003 Jan;33(1):75-9.
10. Giunta S, etal., Neuropeptides. 2010 Feb;44(1):45-51.
11. GOA data from the GO Consortium
12. Gutmann DH, etal., J Neurosci Res. 1993 Oct 1;36(2):216-23.
13. Gutmann DH, etal., Neuropathol Appl Neurobiol. 2000 Aug;26(4):361-7.
14. Gutmann DH, etal., Prog Brain Res. 1995;105:327-35.
15. Hirayama M, etal., Mol Cell Proteomics. 2013 May;12(5):1377-94. doi: 10.1074/mcp.M112.024802. Epub 2013 Jan 28.
16. Hsueh YP, etal., J Neurosci. 2001 Jun 1;21(11):3764-70.
17. KEGG
18. Li Y, etal., Cell 1992 Apr 17;69(2):275-81.
19. Lin YL and Hsueh YP, Biochem Biophys Res Commun. 2008 May 2;369(2):747-52. Epub 2008 Feb 29.
20. Lu D, etal., Cancer. 2003 Jan 15;97(2):441-9.
21. Marui T, etal., Am J Med Genet B Neuropsychiatr Genet. 2004 Nov 15;131B(1):43-7.
22. Metheny LJ and Skuse GR, Exp Cell Res. 1996 Oct 10;228(1):44-9.
23. MGD data from the GO Consortium
24. NCBI rat LocusLink and RefSeq merged data July 26, 2002
25. OMIM Disease Annotation Pipeline
26. Patrakitkomjorn S, etal., J Biol Chem. 2008 Apr 4;283(14):9399-413. Epub 2008 Jan 23.
27. Perrin GQ, etal., J Neurosci Res. 2007 May 1;85(6):1347-57. doi: 10.1002/jnr.21226.
28. Pipeline to import KEGG annotations from KEGG into RGD
29. Pipeline to import Pathway Interaction Database annotations from NCI into RGD
30. Qian B, etal., Eur Rev Med Pharmacol Sci. 2018 Sep;22(18):5946-5953. doi: 10.26355/eurrev_201809_15925.
31. Reilly KM, etal., Nat Genet 2000 Sep;26(1):109-13.
32. RGD automated data pipeline
33. RGD automated import pipeline for ClinVar variants, variant-to-disease annotations and gene-to-disease annotations
34. RGD automated import pipeline for gene-chemical interactions
35. Sharif S, etal., J Med Genet. 2011 Apr;48(4):256-60. doi: 10.1136/jmg.2010.081760. Epub 2011 Jan 28.
36. Suzuki H, etal., J Biochem (Tokyo) 1996 Nov;120(5):1048-54.
37. Tentative Sequence Data IDs. TIGR Gene Index, Rat Data
38. Venturin M, etal., Ann Hum Genet. 2005 Sep;69(Pt 5):508-16.
39. VizcaĆ­no MA, etal., Hum Pathol. 2015 Sep;46(9):1323-30. doi: 10.1016/j.humpath.2015.05.014. Epub 2015 May 30.
40. Vogel KS, etal., Science 1999 Dec 10;286(5447):2176-9.
41. Wallace MR, etal., Science. 1990 Jul 13;249(4965):181-6.
42. Wrabetz L, etal., Glia. 1995 Sep;15(1):22-32.
43. Xu GF, etal., Cell 1990 Aug 10;62(3):599-608.
Additional References at PubMed
PMID:2121371   PMID:7671302   PMID:7920653   PMID:7926784   PMID:8563750   PMID:9001241   PMID:9054942   PMID:9878702   PMID:10383727   PMID:10419687   PMID:10442636   PMID:10498620  
PMID:10586246   PMID:10591652   PMID:10594763   PMID:10620616   PMID:10678181   PMID:10844550   PMID:10845775   PMID:11246230   PMID:11297510   PMID:11401406   PMID:11435472   PMID:11788835  
PMID:11793011   PMID:12409258   PMID:12904481   PMID:14724565   PMID:14741381   PMID:14982883   PMID:15039234   PMID:15125795   PMID:15133494   PMID:15665300   PMID:15944386   PMID:16271875  
PMID:16288202   PMID:16298082   PMID:16405917   PMID:16644864   PMID:16648142   PMID:16835260   PMID:16893911   PMID:16906226   PMID:17053831   PMID:17187824   PMID:17299016   PMID:17404841  
PMID:19946888   PMID:20154697   PMID:20661302   PMID:21584524   PMID:22105171   PMID:24431436   PMID:25242307   PMID:25340873   PMID:25931508   PMID:26537900   PMID:32862562   PMID:33574490  


Genomics

Comparative Map Data
Nf1
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
mRatBN7.21064,306,027 - 64,539,112 (+)NCBImRatBN7.2
mRatBN7.2 Ensembl1064,306,301 - 64,536,658 (+)Ensembl
Rnor_6.01066,732,460 - 66,928,706 (+)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl1066,690,133 - 66,928,903 (+)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.01064,826,693 - 64,916,699 (-)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
Rnor_5.01064,719,521 - 64,758,677 (-)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.41065,574,833 - 65,766,305 (+)NCBIRGSC3.4rn4RGSC3.4
RGSC_v3.11065,545,464 - 65,779,928 (+)NCBI
Celera1063,277,856 - 63,507,181 (+)NCBICelera
Cytogenetic Map10q25NCBI
NF1
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh381731,094,927 - 31,377,677 (+)NCBIGRCh38GRCh38hg38GRCh38
GRCh38.p13 Ensembl1731,094,927 - 31,382,116 (+)EnsemblGRCh38hg38GRCh38
GRCh371729,421,945 - 29,704,695 (+)NCBIGRCh37GRCh37hg19GRCh37
Build 361726,446,121 - 26,728,821 (+)NCBINCBI36hg18NCBI36
Build 341726,446,242 - 26,725,590NCBI
Celera1726,342,778 - 26,625,011 (+)NCBI
Cytogenetic Map17q11.2NCBI
HuRef1725,632,559 - 25,915,183 (+)NCBIHuRef
CHM1_11729,485,166 - 29,767,533 (+)NCBICHM1_1
T2T-CHM13v2.01732,040,661 - 32,323,039 (+)NCBI
Nf1
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm391179,223,541 - 79,472,435 (+)NCBIGRCm39mm39
GRCm39 Ensembl1179,230,519 - 79,472,438 (+)Ensembl
GRCm381179,339,590 - 79,581,609 (+)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl1179,339,693 - 79,581,612 (+)EnsemblGRCm38mm10GRCm38
MGSCv371179,153,394 - 79,395,111 (+)NCBIGRCm37mm9NCBIm37
MGSCv361179,156,087 - 79,397,804 (+)NCBImm8
Celera1189,016,599 - 89,214,295 (+)NCBICelera
Cytogenetic Map11B5NCBI
cM Map1146.74NCBI
Nf1
(Chinchilla lanigera - long-tailed chinchilla)
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0 EnsemblNW_0049554816,145,855 - 6,404,179 (+)EnsemblChiLan1.0
ChiLan1.0NW_0049554816,145,855 - 6,404,179 (+)NCBIChiLan1.0ChiLan1.0
NF1
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
PanPan1.11726,160,857 - 26,439,295 (-)NCBIpanpan1.1PanPan1.1panPan2
PanPan1.1 Ensembl1726,160,855 - 26,439,295 (-)Ensemblpanpan1.1panPan2
Mhudiblu_PPA_v01725,425,081 - 25,703,689 (-)NCBIMhudiblu_PPA_v0panPan3
NF1
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.1941,467,460 - 41,679,388 (-)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
CanFam3.1 Ensembl941,469,416 - 41,679,382 (-)EnsemblCanFam3.1canFam3CanFam3.1
Dog10K_Boxer_Tasha940,629,334 - 40,903,263 (-)NCBI
ROS_Cfam_1.0942,288,289 - 42,562,339 (-)NCBI
UMICH_Zoey_3.1941,071,709 - 41,345,537 (-)NCBI
UNSW_CanFamBas_1.0941,366,542 - 41,640,551 (-)NCBI
UU_Cfam_GSD_1.0941,442,649 - 41,716,759 (-)NCBI
Nf1
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HiC_Itri_2NW_02440560240,516,678 - 40,718,544 (-)NCBI
SpeTri2.0NW_0049365383,394,623 - 3,596,025 (-)NCBISpeTri2.0SpeTri2.0SpeTri2.0
NF1
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 Ensembl1243,489,171 - 43,754,176 (-)EnsemblSscrofa11.1susScr11Sscrofa11.1
Sscrofa11.11243,487,098 - 43,754,205 (-)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
Sscrofa10.21245,314,405 - 45,511,909 (-)NCBISscrofa10.2Sscrofa10.2susScr3
NF1
(Chlorocebus sabaeus - green monkey)
Green Monkey AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.11624,550,983 - 24,836,311 (+)NCBIChlSab1.1chlSab2
ChlSab1.1 Ensembl1624,550,977 - 24,836,307 (+)EnsemblChlSab1.1chlSab2
Vero_WHO_p1.0NW_0236660755,239,619 - 5,527,625 (-)NCBIVero_WHO_p1.0
Nf1
(Heterocephalus glaber - naked mole-rat)
Naked Mole-rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla_female_1.0 EnsemblNW_0046248753,636,924 - 3,956,576 (+)EnsemblHetGla_female_1.0hetGla2
HetGla 1.0NW_0046248753,636,762 - 3,959,991 (+)NCBIHetGla_female_1.0hetGla2

Position Markers
D10Got80  
Rat AssemblyChrPosition (strand)SourceJBrowse
mRatBN7.21064,457,923 - 64,458,117 (+)MAPPERmRatBN7.2
Rnor_6.01066,842,228 - 66,842,421NCBIRnor6.0
Rnor_5.01064,806,285 - 64,806,478UniSTSRnor5.0
RGSC_v3.41065,685,322 - 65,685,516RGDRGSC3.4
RGSC_v3.41065,685,323 - 65,685,516UniSTSRGSC3.4
RGSC_v3.11065,698,945 - 65,699,139RGD
Celera1063,428,831 - 63,429,020UniSTS
RH 2.0 Map10616.4RGD
Cytogenetic Map10q25UniSTS
D10Mco72  
Rat AssemblyChrPosition (strand)SourceJBrowse
mRatBN7.21064,432,767 - 64,433,003 (+)MAPPERmRatBN7.2
Rnor_6.01066,817,079 - 66,817,314NCBIRnor6.0
Rnor_5.01064,831,387 - 64,831,622UniSTSRnor5.0
RGSC_v3.41065,660,188 - 65,660,424RGDRGSC3.4
RGSC_v3.41065,660,189 - 65,660,424UniSTSRGSC3.4
RGSC_v3.11065,673,811 - 65,674,047RGD
Celera1063,403,703 - 63,403,970UniSTS
Cytogenetic Map10q25UniSTS
AW491894  
Rat AssemblyChrPosition (strand)SourceJBrowse
mRatBN7.21064,486,660 - 64,486,790 (+)MAPPERmRatBN7.2
Rnor_6.01066,870,949 - 66,871,078NCBIRnor6.0
Rnor_5.01064,777,557 - 64,777,686UniSTSRnor5.0
RGSC_v3.41065,714,307 - 65,714,436UniSTSRGSC3.4
Celera1063,457,474 - 63,457,603UniSTS
Cytogenetic Map10q25UniSTS
RH142717  
Rat AssemblyChrPosition (strand)SourceJBrowse
mRatBN7.21064,473,794 - 64,474,075 (+)MAPPERmRatBN7.2
Rnor_6.01066,858,082 - 66,858,362NCBIRnor6.0
Rnor_5.01064,790,273 - 64,790,553UniSTSRnor5.0
RGSC_v3.41065,701,440 - 65,701,720UniSTSRGSC3.4
Celera1063,444,607 - 63,444,887UniSTS
Cytogenetic Map10q25UniSTS
D11Bhm106  
Rat AssemblyChrPosition (strand)SourceJBrowse
mRatBN7.21064,404,539 - 64,404,628 (+)MAPPERmRatBN7.2
Rnor_6.01066,788,850 - 66,788,938NCBIRnor6.0
Rnor_5.01064,859,868 - 64,859,956UniSTSRnor5.0
RGSC_v3.41065,631,656 - 65,631,744UniSTSRGSC3.4
Celera1063,375,687 - 63,375,775UniSTS
Cytogenetic Map10q25UniSTS
Nf1  
Rat AssemblyChrPosition (strand)SourceJBrowse
mRatBN7.21064,519,077 - 64,519,218 (+)MAPPERmRatBN7.2
Rnor_6.01066,911,305 - 66,911,445NCBIRnor6.0
Rnor_5.01064,737,385 - 64,737,525UniSTSRnor5.0
RGSC_v3.41065,748,301 - 65,748,441UniSTSRGSC3.4
Celera1063,489,772 - 63,489,912UniSTS
Cytogenetic Map10q25UniSTS
RH131618  
Rat AssemblyChrPosition (strand)SourceJBrowse
mRatBN7.21064,419,404 - 64,419,596 (+)MAPPERmRatBN7.2
Rnor_6.01066,803,717 - 66,803,908NCBIRnor6.0
Rnor_5.01064,844,793 - 64,844,984UniSTSRnor5.0
RGSC_v3.41065,646,827 - 65,647,018UniSTSRGSC3.4
Celera1063,390,342 - 63,390,533UniSTS
Cytogenetic Map10q25UniSTS
RH142205  
Rat AssemblyChrPosition (strand)SourceJBrowse
mRatBN7.21064,432,992 - 64,433,152 (+)MAPPERmRatBN7.2
Rnor_6.01066,817,304 - 66,817,463NCBIRnor6.0
Rnor_5.01064,831,238 - 64,831,397UniSTSRnor5.0
RGSC_v3.41065,660,414 - 65,660,573UniSTSRGSC3.4
Celera1063,403,960 - 63,404,119UniSTS
Cytogenetic Map10q25UniSTS
RH143395  
Rat AssemblyChrPosition (strand)SourceJBrowse
mRatBN7.21064,427,282 - 64,427,411 (+)MAPPERmRatBN7.2
Rnor_6.01066,811,595 - 66,811,723NCBIRnor6.0
Rnor_5.01064,836,978 - 64,837,106UniSTSRnor5.0
RGSC_v3.41065,654,705 - 65,654,833UniSTSRGSC3.4
Celera1063,398,220 - 63,398,348UniSTS
Cytogenetic Map10q25UniSTS
BI279325  
Rat AssemblyChrPosition (strand)SourceJBrowse
mRatBN7.21064,486,059 - 64,486,265 (+)MAPPERmRatBN7.2
Rnor_6.01066,870,348 - 66,870,553NCBIRnor6.0
Rnor_5.01064,778,082 - 64,778,287UniSTSRnor5.0
RGSC_v3.41065,713,706 - 65,713,911UniSTSRGSC3.4
Celera1063,456,873 - 63,457,078UniSTS
Cytogenetic Map10q25UniSTS
BI302108  
Rat AssemblyChrPosition (strand)SourceJBrowse
mRatBN7.21064,451,223 - 64,451,392 (+)MAPPERmRatBN7.2
Rnor_6.01066,835,529 - 66,835,697NCBIRnor6.0
Rnor_5.01064,813,009 - 64,813,177UniSTSRnor5.0
RGSC_v3.41065,678,624 - 65,678,792UniSTSRGSC3.4
Celera1063,422,132 - 63,422,300UniSTS
Cytogenetic Map10q25UniSTS
RH94434  
Rat AssemblyChrPosition (strand)SourceJBrowse
mRatBN7.21064,536,287 - 64,536,484 (+)MAPPERmRatBN7.2
Rnor_6.01066,928,509 - 66,928,705NCBIRnor6.0
Rnor_5.01064,719,522 - 64,719,718UniSTSRnor5.0
RGSC_v3.41065,766,108 - 65,766,304UniSTSRGSC3.4
Celera1063,506,984 - 63,507,180UniSTS
Cytogenetic Map10q25UniSTS
RH136900  
Rat AssemblyChrPosition (strand)SourceJBrowse
mRatBN7.21064,456,769 - 64,456,929 (+)MAPPERmRatBN7.2
Rnor_6.01066,841,074 - 66,841,233NCBIRnor6.0
Rnor_5.01064,807,473 - 64,807,632UniSTSRnor5.0
RGSC_v3.41065,684,169 - 65,684,328UniSTSRGSC3.4
Celera1063,427,677 - 63,427,836UniSTS
Cytogenetic Map10q25UniSTS
RH136954  
Rat AssemblyChrPosition (strand)SourceJBrowse
mRatBN7.21064,472,794 - 64,472,985 (+)MAPPERmRatBN7.2
Rnor_6.01066,857,082 - 66,857,272NCBIRnor6.0
Rnor_5.01064,791,363 - 64,791,553UniSTSRnor5.0
RGSC_v3.41065,700,440 - 65,700,630UniSTSRGSC3.4
Celera1063,443,607 - 63,443,797UniSTS
Cytogenetic Map10q25UniSTS
RH139234  
Rat AssemblyChrPosition (strand)SourceJBrowse
mRatBN7.21064,414,235 - 64,414,459 (+)MAPPERmRatBN7.2
Rnor_6.01066,798,545 - 66,798,768NCBIRnor6.0
Rnor_5.01064,850,038 - 64,850,261UniSTSRnor5.0
RGSC_v3.41065,641,351 - 65,641,574UniSTSRGSC3.4
Celera1063,385,382 - 63,385,605UniSTS
Cytogenetic Map10q25UniSTS
BF391060  
Rat AssemblyChrPosition (strand)SourceJBrowse
mRatBN7.21064,484,495 - 64,484,675 (+)MAPPERmRatBN7.2
Rnor_6.01066,868,784 - 66,868,963NCBIRnor6.0
Rnor_5.01064,779,672 - 64,779,851UniSTSRnor5.0
RGSC_v3.41065,712,142 - 65,712,321UniSTSRGSC3.4
Celera1063,455,309 - 63,455,488UniSTS
Cytogenetic Map10q25UniSTS
AA848827  
Rat AssemblyChrPosition (strand)SourceJBrowse
mRatBN7.21064,443,723 - 64,443,904 (+)MAPPERmRatBN7.2
Rnor_6.01066,828,029 - 66,828,209NCBIRnor6.0
Rnor_5.01064,820,497 - 64,820,677UniSTSRnor5.0
Rnor_5.01064,820,473 - 64,820,677UniSTSRnor5.0
RGSC_v3.41065,671,124 - 65,671,304UniSTSRGSC3.4
Celera1063,414,632 - 63,414,812UniSTS
Cytogenetic Map10q25UniSTS
Omg  
Rat AssemblyChrPosition (strand)SourceJBrowse
mRatBN7.21064,461,755 - 64,461,994 (+)MAPPERmRatBN7.2
Rnor_6.01066,846,060 - 66,846,298NCBIRnor6.0
Rnor_5.01064,802,408 - 64,802,646UniSTSRnor5.0
RGSC_v3.41065,689,155 - 65,689,393UniSTSRGSC3.4
Celera1063,432,659 - 63,432,897UniSTS
Cytogenetic Map10q25UniSTS


QTLs in Region (mRatBN7.2)
The following QTLs overlap with this region.    Full Report CSV TAB Printer Gviewer
RGD IDSymbolNameLODP ValueTraitSub TraitChrStartStopSpecies
70223Bp57Blood pressure QTL 575arterial blood pressure trait (VT:2000000)systolic blood pressure (CMO:0000004)10180676123Rat
8662860Vetf10Vascular elastic tissue fragility QTL 10artery integrity trait (VT:0010639)number of ruptures of the internal elastic lamina of the abdominal aorta and iliac arteries (CMO:0002562)10615418273453136Rat
61427Cia16Collagen induced arthritis QTL 163.2joint integrity trait (VT:0010548)joint inflammation composite score (CMO:0000919)10635789696121100Rat
2303118Mamtr7Mammary tumor resistance QTL 70.003mammary gland integrity trait (VT:0010552)mammary tumor growth rate (CMO:0000344)109658275104670812Rat
2301967Cm73Cardiac mass QTL 734.55heart left ventricle mass (VT:0007031)heart left ventricle weight to body weight ratio (CMO:0000530)101448701189062041Rat
631268Cia21Collagen induced arthritis QTL 213.1joint integrity trait (VT:0010548)joint inflammation composite score (CMO:0000919)1014487011104060283Rat
2316949Gluco60Glucose level QTL 603.7blood glucose amount (VT:0000188)blood glucose level (CMO:0000046)1014487011107057807Rat
2313055Bw96Body weight QTL 963.60.0001body mass (VT:0001259)body weight (CMO:0000012)101960648364606483Rat
2313087Bmd80Bone mineral density QTL 803.20.0001tibia mineral mass (VT:1000283)total volumetric bone mineral density (CMO:0001728)101960648364606483Rat
1554317Bmd4Bone mineral density QTL 49.40.0001lumbar vertebra mineral mass (VT:0010511)volumetric bone mineral density (CMO:0001553)101981604299406971Rat
724556Pur2Proteinuria QTL 25.5urine protein amount (VT:0005160)urine protein level (CMO:0000591)102242750090627625Rat
61354Pia10Pristane induced arthritis QTL 100.01joint integrity trait (VT:0010548)joint inflammation composite score (CMO:0000919)1023444813104060283Rat
631267Cia20Collagen induced arthritis QTL 203.2joint integrity trait (VT:0010548)joint inflammation composite score (CMO:0000919)1023444813104060283Rat
61325Aia5Adjuvant induced arthritis QTL 50.01joint integrity trait (VT:0010548)joint inflammation composite score (CMO:0000919)1023444813104060283Rat
1298069Bp168Blood pressure QTL 1685.5blood pressure trait (VT:0000183)systolic blood pressure (CMO:0000004)102652195798003205Rat
631542Bp82Blood pressure QTL 826.8arterial blood pressure trait (VT:2000000)systolic blood pressure (CMO:0000004)102652195798952741Rat
2300171Bmd58Bone mineral density QTL 584.90.0001lumbar vertebra mineral mass (VT:0010511)volumetric bone mineral density (CMO:0001553)102694462871944628Rat
10402859Bp381Blood pressure QTL 3810.002arterial blood pressure trait (VT:2000000)mean arterial blood pressure (CMO:0000009)102760646872606468Rat
2292441Bp308Blood pressure QTL 308arterial blood pressure trait (VT:2000000)mean arterial blood pressure (CMO:0000009)102760646872606468Rat
724527Bp148Blood pressure QTL 1480.0001arterial blood pressure trait (VT:2000000)mean arterial blood pressure (CMO:0000009)102845313673453136Rat
1331791Cm31Cardiac mass QTL 313.84606heart mass (VT:0007028)heart wet weight (CMO:0000069)1029299504107211142Rat
631557Bp136Blood pressure QTL 1360.003arterial blood pressure trait (VT:2000000)systolic blood pressure (CMO:0000004)103063205375632053Rat
1576311Pia26Pristane induced arthritis QTL 26joint integrity trait (VT:0010548)joint inflammation composite score (CMO:0000919)103122402675632053Rat
1578779Tcas10Tongue tumor susceptibility QTL 103.12tongue integrity trait (VT:0010553)number of squamous cell tumors of the tongue with diameter greater than 3 mm (CMO:0001950)103129743976297439Rat
1576319Cia29Collagen induced arthritis QTL 29joint integrity trait (VT:0010548)joint inflammation composite score (CMO:0000919)103397392178973921Rat
2317042Aia20Adjuvant induced arthritis QTL 203.38joint integrity trait (VT:0010548)right rear ankle joint diameter (CMO:0002150)103756507982565079Rat
2317043Aia7Adjuvant induced arthritis QTL 73.82joint integrity trait (VT:0010548)left rear ankle joint diameter (CMO:0002149)103756507982565079Rat
1576308Schws1Schwannoma susceptibility QTL 10.0041nervous system integrity trait (VT:0010566)percentage of study population developing trigeminal nerve neurilemmomas during a period of time (CMO:0002017)1040035094102359817Rat
631269Cia22Collagen induced arthritis QTL 228.9joint integrity trait (VT:0010548)joint inflammation composite score (CMO:0000919)1040035094104060283Rat
631270Cia23Collagen induced arthritis QTL 233.9joint integrity trait (VT:0010548)joint inflammation composite score (CMO:0000919)1040035094104060283Rat
631552Vetf2Vascular elastic tissue fragility QTL 24.50.0002aorta elastic tissue integrity trait (VT:0010556)artery internal elastic lamina non-tumorous lesion count (CMO:0001913)104114263386142633Rat
61463Bp12Blood pressure QTL 126.30.0001arterial blood pressure trait (VT:2000000)systolic blood pressure (CMO:0000004)104133325886333258Rat
8552805Bw145Body weight QTL 1452.2body mass (VT:0001259)change in body weight to body weight ratio (CMO:0002216)104194452678307017Rat
1298078Stresp5Stress response QTL 52.990.00025blood corticosterone amount (VT:0005345)plasma corticosterone level (CMO:0001173)1042045676104670812Rat
70188BpQTLcluster1Blood pressure QTL cluster 14.864arterial blood pressure trait (VT:2000000)diastolic blood pressure (CMO:0000005)14232313287323132Rat
70188BpQTLcluster1Blood pressure QTL cluster 14.864arterial blood pressure trait (VT:2000000)systolic blood pressure (CMO:0000004)14232313287323132Rat
70188BpQTLcluster1Blood pressure QTL cluster 14.864arterial blood pressure trait (VT:2000000)mean arterial blood pressure (CMO:0000009)14232313287323132Rat
70188BpQTLcluster1Blood pressure QTL cluster 14.864arterial blood pressure trait (VT:2000000)pulse pressure (CMO:0000292)14232313287323132Rat
70198BpQTLcluster9Blood pressure QTL cluster 92.94arterial blood pressure trait (VT:2000000)mean arterial blood pressure (CMO:0000009)104232313287323132Rat
6893342Cm78Cardiac mass QTL 780.10.88heart mass (VT:0007028)heart weight to body weight ratio (CMO:0000074)104287676679813922Rat
9589030Epfw9Epididymal fat weight QTL 919.240.001epididymal fat pad mass (VT:0010421)epididymal fat pad weight to body weight ratio (CMO:0000658)104444169989441699Rat
7411614Foco18Food consumption QTL 180.001eating behavior trait (VT:0001431)feed conversion ratio (CMO:0001312)104444169989441699Rat
8694173Bw149Body weight QTL 1494.380.001body mass (VT:0001259)body weight gain (CMO:0000420)104444169989441699Rat
2300218Hpcl2Hepatic cholesterol level QTL 2liver cholesterol amount (VT:0010498)liver cholesterol level (CMO:0001597)104502965095600334Rat
631547Bp87Blood pressure QTL 874.5arterial blood pressure trait (VT:2000000)systolic blood pressure (CMO:0000004)104736947092369470Rat
2293705Bmd25Bone mineral density QTL 257.10.0001femur mineral mass (VT:0010011)cortical volumetric bone mineral density (CMO:0001730)104944455181709989Rat
7207811Bmd90Bone mineral density QTL 905.2femur size trait (VT:1000369)femoral neck cross-sectional area (CMO:0001697)104944455181709989Rat
2293652Bmd22Bone mineral density QTL 224.90.0001femur mineral mass (VT:0010011)total volumetric bone mineral density (CMO:0001728)104944455181709989Rat
2293669Bmd33Bone mineral density QTL 334.50.0001femur strength trait (VT:0010010)femoral neck polar moment of inertia (CMO:0001670)104944455181709989Rat
2293679Bmd30Bone mineral density QTL 303.50.0001femur mineral mass (VT:0010011)total volumetric bone mineral density (CMO:0001728)104944455181709989Rat
1549846Scl47Serum cholesterol level QTL 473.6blood cholesterol amount (VT:0000180)serum total cholesterol level (CMO:0000363)105057470795574707Rat
70364Bp72Blood pressure QTL 72arterial blood pressure trait (VT:2000000)mean arterial blood pressure (CMO:0000009)105112110096121100Rat
61387Bp1Blood pressure QTL 15.1arterial blood pressure trait (VT:2000000)systolic blood pressure (CMO:0000004)1051770177107211142Rat
61387Bp1Blood pressure QTL 15.1arterial blood pressure trait (VT:2000000)diastolic blood pressure (CMO:0000005)1051770177107211142Rat
1359017Hrtrt21Heart rate QTL 212.4heart pumping trait (VT:2000009)heart rate (CMO:0000002)105177294096772940Rat
631530Tls3T-lymphoma susceptibility QTL 300.0001thymus integrity trait (VT:0010555)percentage of study population developing T-cell lymphomas during a period of time (CMO:0001911)105177461295600334Rat
631535Cm51Cardiac mass QTL 513heart mass (VT:0007028)calculated heart weight (CMO:0000073)105178628291669536Rat
2306787Ean3Experimental allergic neuritis QTL 33.1nervous system integrity trait (VT:0010566)body weight loss (CMO:0001399)105379738566979128Rat
70171Cari1Carrageenan-induced inflammation QTL 14.90.0005hypodermis integrity trait (VT:0010550)inflammatory exudate volume (CMO:0001429)1053797385107211142Rat
70164Bw21Body weight QTL 214.360.00005body mass (VT:0001259)body weight (CMO:0000012)105379749498952626Rat
1354608Cm33Cardiac mass QTL 332.8heart left ventricle mass (VT:0007031)heart left ventricle wet weight (CMO:0000071)105480929299809292Rat
2312662Slep8Serum leptin concentration QTL 80.05blood leptin amount (VT:0005667)serum leptin level (CMO:0000780)1057134272102134272Rat
2312668Scl65Serum cholesterol level QTL 650.001blood cholesterol amount (VT:0000180)serum total cholesterol level (CMO:0000363)1057134272102134272Rat
2312672Insul15Insulin level QTL 150.01blood insulin amount (VT:0001560)serum insulin level (CMO:0000358)1057134272102134272Rat
1549831Bss6Bone structure and strength QTL 64lumbar vertebra strength trait (VT:0010574)vertebra ultimate force (CMO:0001678)1057576521102576521Rat
2293698Bss43Bone structure and strength QTL 435.330.0001lumbar vertebra size trait (VT:0010518)lumbar vertebra cross-sectional area (CMO:0001689)1059209888104209888Rat
1331839Eae18bExperimental allergic encephalomyelitis QTL 18b5.80.03nervous system integrity trait (VT:0010566)experimental autoimmune encephalomyelitis severity score (CMO:0001419)106124830367785171Rat
70363Bp71Blood pressure QTL 710.04arterial blood pressure trait (VT:2000000)mean arterial blood pressure (CMO:0000009)106134527681714865Rat
2306970Anxrr22Anxiety related response QTL 225.95fear/anxiety-related behavior trait (VT:1000241)number of periods of voluntary immobility (CMO:0001045)106134527698211570Rat
6893336Cm75Cardiac mass QTL 750.10.87heart mass (VT:0007028)heart weight to body weight ratio (CMO:0000074)106134527699703528Rat
1558643Cm44Cardiac mass QTL 444.80.0000368heart mass (VT:0007028)heart wet weight (CMO:0000069)106134527699703528Rat
631526Bp76Blood pressure QTL 760.0001arterial blood pressure trait (VT:2000000)systolic blood pressure (CMO:0000004)106134541366743655Rat
61402Niddm3Non-insulin dependent diabetes mellitus QTL 34.58blood glucose amount (VT:0000188)blood glucose level (CMO:0000046)106134541382564856Rat
2313103Bss80Bone structure and strength QTL 8020.0001tibia strength trait (VT:1000284)tibia midshaft endosteal cross-sectional area (CMO:0001716)1062057807107057807Rat
2313105Bss79Bone structure and strength QTL 791.80.0001tibia size trait (VT:0100001)tibia midshaft cross-sectional area (CMO:0001717)1062057807107057807Rat
61449Ciaa2CIA Autoantibody QTL 27.1blood autoantibody amount (VT:0003725)calculated serum anti-type 2 collagen antibody titer (CMO:0001279)1063221094107211142Rat

miRNA Target Status

Predicted Target Of
Summary Value
Count of predictions:277
Count of miRNA genes:171
Interacting mature miRNAs:199
Transcripts:ENSRNOT00000046262
Prediction methods:Microtar, Miranda, Rnahybrid, Targetscan
Result types:miRGate_prediction

The detailed report is available here: Full Report CSV TAB Printer

miRNA Target Status data imported from miRGate (http://mirgate.bioinfo.cnio.es/).
For more information about miRGate, see PMID:25858286 or access the full paper here.


Expression


RNA-SEQ Expression
High: > 1000 TPM value   Medium: Between 11 and 1000 TPM
Low: Between 0.5 and 10 TPM   Below Cutoff: < 0.5 TPM

alimentary part of gastrointestinal system circulatory system endocrine system exocrine system hemolymphoid system hepatobiliary system integumental system musculoskeletal system nervous system renal system reproductive system respiratory system appendage
High
Medium 34 28 12 16 12 6 6 74 28 39 10 6
Low 3 9 29 29 3 29 2 5 7 2 1 2
Below cutoff

Sequence


Reference Sequences
RefSeq Acc Id: ENSRNOT00000046262   ⟹   ENSRNOP00000050393
RefSeq Status:
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.2 Ensembl1064,306,301 - 64,536,485 (+)Ensembl
Rnor_6.0 Ensembl1066,690,133 - 66,928,706 (+)Ensembl
RefSeq Acc Id: ENSRNOT00000089538   ⟹   ENSRNOP00000069925
RefSeq Status:
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.2 Ensembl1064,306,301 - 64,536,485 (+)Ensembl
Rnor_6.0 Ensembl1066,732,390 - 66,928,903 (+)Ensembl
RefSeq Acc Id: ENSRNOT00000098259   ⟹   ENSRNOP00000089070
RefSeq Status:
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.2 Ensembl1064,350,476 - 64,536,485 (+)Ensembl
RefSeq Acc Id: ENSRNOT00000102179   ⟹   ENSRNOP00000093378
RefSeq Status:
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.2 Ensembl1064,306,301 - 64,536,485 (+)Ensembl
RefSeq Acc Id: ENSRNOT00000106713   ⟹   ENSRNOP00000078171
RefSeq Status:
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.2 Ensembl1064,306,301 - 64,536,658 (+)Ensembl
RefSeq Acc Id: ENSRNOT00000118558   ⟹   ENSRNOP00000085815
RefSeq Status:
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.2 Ensembl1064,348,130 - 64,536,485 (+)Ensembl
RefSeq Acc Id: NM_012609   ⟹   NP_036741
RefSeq Status: PROVISIONAL
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.21064,306,301 - 64,536,485 (+)NCBI
Rnor_6.01066,732,460 - 66,928,706 (+)NCBI
Rnor_5.01064,719,521 - 64,758,677 (-)NCBI
Rnor_5.01064,826,693 - 64,916,699 (-)NCBI
RGSC_v3.41065,574,833 - 65,766,305 (+)RGD
Celera1063,277,856 - 63,507,181 (+)RGD
Sequence:
RefSeq Acc Id: XM_039085200   ⟹   XP_038941128
RefSeq Status:
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.21064,306,027 - 64,539,112 (+)NCBI
RefSeq Acc Id: XM_039085201   ⟹   XP_038941129
RefSeq Status:
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.21064,306,435 - 64,535,948 (+)NCBI
Reference Sequences
RefSeq Acc Id: NP_036741   ⟸   NM_012609
- UniProtKB: P97526 (UniProtKB/Swiss-Prot)
- Sequence:
RefSeq Acc Id: ENSRNOP00000069925   ⟸   ENSRNOT00000089538
RefSeq Acc Id: ENSRNOP00000050393   ⟸   ENSRNOT00000046262
RefSeq Acc Id: XP_038941128   ⟸   XM_039085200
- Peptide Label: isoform X1
RefSeq Acc Id: XP_038941129   ⟸   XM_039085201
- Peptide Label: isoform X2
RefSeq Acc Id: ENSRNOP00000078171   ⟸   ENSRNOT00000106713
RefSeq Acc Id: ENSRNOP00000089070   ⟸   ENSRNOT00000098259
RefSeq Acc Id: ENSRNOP00000093378   ⟸   ENSRNOT00000102179
RefSeq Acc Id: ENSRNOP00000085815   ⟸   ENSRNOT00000118558
Protein Domains
CRAL-TRIO   Ras-GAP

Transcriptome

eQTL   View at Phenogen
WGCNA   View at Phenogen
Tissue/Strain Expression   View at Phenogen


Strain Variation

Strain Sequence Variants (MRatBN7.2)
ACI/EurMcwi (2019)
Visual CSV TAB Printer
Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: MCW
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
ACI/N (2020)
Visual CSV TAB Printer
Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: NIH
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
BN-Lx/CubMcwi (2019)
Visual CSV TAB Printer
Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: MCW
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
BN/NHsdMcwi (2019)
Visual CSV TAB Printer
Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: MCW
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
BN/NHsdMcwi (2020)
Visual CSV TAB Printer
Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: MCW
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
BN/SsN (2020)
Visual CSV TAB Printer
Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: NIH
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
BUF/N (2020)
Visual CSV TAB Printer
Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: NIH
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
BXH2/CubMcwi (2020)
Visual CSV TAB Printer
Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: MCW
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
BXH3/CubMcwi (2020)
Visual CSV TAB Printer
Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: MCW
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
DA/OlaHsd (2019)
Visual CSV TAB Printer
Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: Envigo
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
F344/DuCrl (2019)
Visual CSV TAB Printer
Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: Charles River
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
F344/N (2020)
Visual CSV TAB Printer
Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: NIH
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
F344/NCrl (2019)
Visual CSV TAB Printer
Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: Charles River
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
F344/Stm (2019)
Visual CSV TAB Printer
Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: Japan
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
FHH/EurMcwi (2019)
Visual CSV TAB Printer
Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: MCW
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
FXLE16/Stm (2020)
Visual CSV TAB Printer
Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: Japan
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
FXLE18/Stm (2020)
Visual CSV TAB Printer
Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: Japan
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
GK/FarMcwi (2019)
Visual CSV TAB Printer
Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: MCW
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
HXB10/IpcvMcwi (2019)
Visual CSV TAB Printer
Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: MCW
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
HXB2/IpcvMcwi (2019)
Visual CSV TAB Printer
Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: MCW
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
HXB20/IpcvMcwi (2020)
Visual CSV TAB Printer
Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: MCW
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
HXB31/IpcvMcwi (2019)
Visual CSV TAB Printer
Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: MCW
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
HXB4/IpcvMcwi (2020)
Visual CSV TAB Printer
Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: MCW
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
LE/Stm (2019)
Visual CSV TAB Printer
Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: MCW
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
LEW/Crl (2019)
Visual CSV TAB Printer
Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: Charles River
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
LEXF10A/StmMcwi (2020)
Visual CSV TAB Printer
Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: MCW
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
LEXF11/Stm (2020)
Visual CSV TAB Printer
Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: Japan
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
LEXF1A/Stm (2019)
Visual CSV TAB Printer
Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: Japan
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
LEXF1C/Stm (2019)
Visual CSV TAB Printer
Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: Japan
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
LEXF2B/Stm (2019)
Visual CSV TAB Printer
Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: Japan
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
LEXF3/Stm (2020)
Visual CSV TAB Printer
Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: Japan
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
LEXF4/Stm (2020)
Visual CSV TAB Printer
Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: Japan
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
LH/MavRrrcAek (2020)
Visual CSV TAB Printer
Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: Kwitek
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
LL/MavRrrcAek (2020)
Visual CSV TAB Printer
Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: Kwitek
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
LN/MavRrrcAek (2020)
Visual CSV TAB Printer
Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: Kwitek
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
M520/N (2020)
Visual CSV TAB Printer
Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: NIH
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
M520/NRrrcMcwi (2019)
Visual CSV TAB Printer
Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: MCW
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
MR/N (2020)
Visual CSV TAB Printer
Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: NIH
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
MWF/Hsd (2019)
Visual CSV TAB Printer
Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: MCW
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
PVG/Seac (2019)
Visual CSV TAB Printer
Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: Japan
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
SHR/OlalpcvMcwi (2019)
Visual CSV TAB Printer
Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: MCW
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
SHRSP/A3NCrl (2019)
Visual CSV TAB Printer
Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: Charles River
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
SR/JrHsd (2020)
Visual CSV TAB Printer
Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: Envigo
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
SS/JrHsdMcwi (2019)
Visual CSV TAB Printer
Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: MCW
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
WAG/RijCrl (2020)
Visual CSV TAB Printer
Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: Charles River
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
WKY/N (2020)
Visual CSV TAB Printer
Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: NIH
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
WKY/NCrl (2019)
Visual CSV TAB Printer
Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: Charles River
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
WN/N (2020)
Visual CSV TAB Printer
Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: NIH
Description: Dr. Mindy Dwinell - Hybrid rat diversity program

Additional Information

Database Acc Id Source(s)
AGR Gene RGD:3168 AgrOrtholog
BioCyc Gene G2FUF-24023 BioCyc
Ensembl Genes ENSRNOG00000013780 Ensembl, ENTREZGENE, UniProtKB/TrEMBL
Ensembl Protein ENSRNOP00000050393 ENTREZGENE, UniProtKB/TrEMBL
  ENSRNOP00000069925 ENTREZGENE, UniProtKB/TrEMBL
Ensembl Transcript ENSRNOT00000046262 ENTREZGENE, UniProtKB/TrEMBL
  ENSRNOT00000089538 ENTREZGENE, UniProtKB/TrEMBL
Gene3D-CATH 1.10.506.10 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  2.30.29.30 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  3.40.525.10 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
InterPro ARM-type_fold UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  CRAL-TRIO_dom UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  CRAL-TRIO_dom_sf UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  PH-like_dom_sf UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  Ras_GTPase UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  RasGAP_CS UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  RasGAP_dom UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  Rho_GTPase_activation_prot UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
KEGG Report rno:24592 UniProtKB/Swiss-Prot
NCBI Gene 24592 ENTREZGENE
PANTHER PTHR10194 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
Pfam CRAL_TRIO_2 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  RasGAP UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
PhenoGen Nf1 PhenoGen
PROSITE CRAL_TRIO UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  RAS_GTPASE_ACTIV_1 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  RAS_GTPASE_ACTIV_2 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
SMART RasGAP UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  SEC14 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
Superfamily-SCOP SSF48350 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  SSF48371 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
TIGR TC221490
UniProt A0A0G2JWL3_RAT UniProtKB/TrEMBL
  F1LM28_RAT UniProtKB/TrEMBL
  NF1_RAT UniProtKB/Swiss-Prot, ENTREZGENE


Nomenclature History
Date Current Symbol Current Name Previous Symbol Previous Name Description Reference Status
2008-09-25 Nf1  neurofibromin 1  Nf1  neurofibromatosis 1  Nomenclature updated to reflect human and mouse nomenclature 1299863 APPROVED
2002-06-10 Nf1  Neurofibromatosis type 1      Symbol and Name status set to approved 70586 APPROVED

RGD Curation Notes
Note Type Note Reference
gene_expression type I isoform is expressed in brain, pituitary, and testis 729067
gene_expression type II isoform is expressed in heart, kidney, and ovary 729067