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Gene-Chemical Interaction Annotations Click to see Annotation Detail View
Object Symbol | Species | Term | Qualifier | Evidence | With | Reference | Notes | Source | Original Reference(s) | Pank3 | Rat | (1->4)-beta-D-glucan | multiple interactions | ISO | Pank3 (Mus musculus) | 6480464 | [perfluorooctane sulfonic acid co-treated with Cellulose] results in decreased expression of PANK3 mRNA | CTD | PMID:36331819 | Pank3 | Rat | (S)-nicotine | increases expression | ISO | PANK3 (Homo sapiens) | 6480464 | Nicotine results in increased expression of PANK3 mRNA | CTD | PMID:16949557 | Pank3 | Rat | 1,2-dimethylhydrazine | decreases expression | ISO | Pank3 (Mus musculus) | 6480464 | 1 and 2-Dimethylhydrazine results in decreased expression of PANK3 mRNA | CTD | PMID:22206623 | Pank3 | Rat | 17alpha-ethynylestradiol | increases expression | EXP | | 6480464 | Ethinyl Estradiol results in increased expression of PANK3 mRNA | CTD | PMID:29097150 | Pank3 | Rat | 17beta-estradiol | decreases expression | ISO | Pank3 (Mus musculus) | 6480464 | Estradiol results in decreased expression of PANK3 mRNA | CTD | PMID:39298647 | Pank3 | Rat | 2,3,7,8-tetrachlorodibenzodioxine | affects expression | ISO | Pank3 (Mus musculus) | 6480464 | Tetrachlorodibenzodioxin affects the expression of PANK3 mRNA | CTD | PMID:21570461 | Pank3 | Rat | 2,3,7,8-tetrachlorodibenzodioxine | affects expression | EXP | | 6480464 | Tetrachlorodibenzodioxin affects the expression of PANK3 mRNA | CTD | PMID:34747641 | Pank3 | Rat | 2,3,7,8-tetrachlorodibenzodioxine | decreases expression | EXP | | 6480464 | Tetrachlorodibenzodioxin results in decreased expression of PANK3 mRNA | CTD | PMID:32109520 and PMID:33387578 | Pank3 | Rat | 3,4-methylenedioxymethamphetamine | increases expression | ISO | Pank3 (Mus musculus) | 6480464 | N-Methyl-3 and 4-methylenedioxyamphetamine results in increased expression of PANK3 mRNA | CTD | PMID:20188158 | Pank3 | Rat | 4,4'-sulfonyldiphenol | affects expression | ISO | Pank3 (Mus musculus) | 6480464 | bisphenol S affects the expression of PANK3 mRNA | CTD | PMID:39298647 | Pank3 | Rat | 4-hydroxyphenyl retinamide | decreases expression | ISO | Pank3 (Mus musculus) | 6480464 | Fenretinide results in decreased expression of PANK3 mRNA | CTD | PMID:28973697 | Pank3 | Rat | 5-azacytidine | decreases expression | ISO | PANK3 (Homo sapiens) | 6480464 | Azacitidine results in decreased expression of PANK3 mRNA | CTD | PMID:19194470 | Pank3 | Rat | acetamide | decreases expression | EXP | | 6480464 | acetamide results in decreased expression of PANK3 mRNA | CTD | PMID:31881176 | Pank3 | Rat | acrolein | multiple interactions | ISO | PANK3 (Homo sapiens) | 6480464 | [Acrolein co-treated with methacrylaldehyde co-treated with alpha-pinene co-treated with Ozone] results in decreased expression of PANK3 mRNA and [Air Pollutants results in increased abundance of [Acrolein co-treated with methacrylaldehyde co-treated with alpha-pinene co-treated with Ozone]] which results in decreased expression of PANK3 mRNA | CTD | PMID:32699268 | Pank3 | Rat | all-trans-retinoic acid | decreases expression | ISO | PANK3 (Homo sapiens) | 6480464 | Tretinoin results in decreased expression of PANK3 mRNA | CTD | PMID:15498508 | Pank3 | Rat | alpha-pinene | multiple interactions | ISO | PANK3 (Homo sapiens) | 6480464 | [Acrolein co-treated with methacrylaldehyde co-treated with alpha-pinene co-treated with Ozone] results in decreased expression of PANK3 mRNA and [Air Pollutants results in increased abundance of [Acrolein co-treated with methacrylaldehyde co-treated with alpha-pinene co-treated with Ozone]] which results in decreased expression of PANK3 mRNA | CTD | PMID:32699268 | Pank3 | Rat | alpha-Zearalanol | multiple interactions | EXP | | 6480464 | [Zeranol co-treated with perfluorooctanoic acid] results in decreased expression of PANK3 mRNA | CTD | PMID:35163327 | Pank3 | Rat | amitrole | decreases expression | EXP | | 6480464 | Amitrole results in decreased expression of PANK3 mRNA | CTD | PMID:38685447 | Pank3 | Rat | amphetamine | decreases expression | EXP | | 6480464 | Amphetamine results in decreased expression of PANK3 mRNA | CTD | PMID:30779732 | Pank3 | Rat | benzo[a]pyrene | affects methylation | ISO | PANK3 (Homo sapiens) | 6480464 | Benzo(a)pyrene affects the methylation of PANK3 promoter | CTD | PMID:27901495 | Pank3 | Rat | benzo[b]fluoranthene | decreases expression | ISO | Pank3 (Mus musculus) | 6480464 | benzo(b)fluoranthene results in decreased expression of PANK3 mRNA | CTD | PMID:26377693 | Pank3 | Rat | bis(2-ethylhexyl) phthalate | decreases expression | ISO | Pank3 (Mus musculus) | 6480464 | Diethylhexyl Phthalate results in decreased expression of PANK3 mRNA | CTD | PMID:33754040 and PMID:34319233 | Pank3 | Rat | bisphenol A | increases expression | ISO | PANK3 (Homo sapiens) | 6480464 | bisphenol A results in increased expression of PANK3 mRNA | CTD | PMID:25047013 | Pank3 | Rat | bisphenol A | affects expression | ISO | Pank3 (Mus musculus) | 6480464 | bisphenol A affects the expression of PANK3 mRNA | CTD | PMID:35341816 | Pank3 | Rat | bisphenol A | increases expression | EXP | | 6480464 | bisphenol A results in increased expression of PANK3 mRNA | CTD | PMID:25181051 | Pank3 | Rat | cadmium dichloride | decreases expression | ISO | Pank3 (Mus musculus) | 6480464 | Cadmium Chloride results in decreased expression of PANK3 mRNA | CTD | PMID:24982889 | Pank3 | Rat | chlorpyrifos | decreases expression | ISO | Pank3 (Mus musculus) | 6480464 | Chlorpyrifos results in decreased expression of PANK3 mRNA | CTD | PMID:37019170 | Pank3 | Rat | choline | multiple interactions | ISO | Pank3 (Mus musculus) | 6480464 | [Methionine deficiency co-treated with Choline deficiency co-treated with Folic Acid deficiency] results in increased methylation of PANK3 gene | CTD | PMID:20938992 | Pank3 | Rat | clozapine | multiple interactions | ISO | PANK3 (Homo sapiens) | 6480464 | [Cuprizone co-treated with Clozapine] results in increased expression of PANK3 protein | CTD | PMID:34122009 | Pank3 | Rat | cobalt dichloride | increases expression | ISO | PANK3 (Homo sapiens) | 6480464 | cobaltous chloride results in increased expression of PANK3 mRNA | CTD | PMID:19376846 | Pank3 | Rat | copper(II) sulfate | decreases expression | ISO | PANK3 (Homo sapiens) | 6480464 | Copper Sulfate results in decreased expression of PANK3 mRNA | CTD | PMID:19549813 | Pank3 | Rat | Cuprizon | multiple interactions | ISO | PANK3 (Homo sapiens) | 6480464 | [Cuprizone co-treated with Clozapine] results in increased expression of PANK3 protein | CTD | PMID:34122009 | Pank3 | Rat | cyclosporin A | decreases expression | ISO | PANK3 (Homo sapiens) | 6480464 | Cyclosporine results in decreased expression of PANK3 mRNA | CTD | PMID:20106945 | Pank3 | Rat | Dibutyl phosphate | affects expression | ISO | PANK3 (Homo sapiens) | 6480464 | di-n-butylphosphoric acid affects the expression of PANK3 mRNA | CTD | PMID:37042841 | Pank3 | Rat | dicrotophos | decreases expression | ISO | PANK3 (Homo sapiens) | 6480464 | dicrotophos results in decreased expression of PANK3 mRNA | CTD | PMID:28302478 | Pank3 | Rat | dioxygen | decreases expression | ISO | Pank3 (Mus musculus) | 6480464 | Oxygen deficiency results in decreased expression of PANK3 mRNA | CTD | PMID:20880076 | Pank3 | Rat | ethyl methanesulfonate | decreases expression | ISO | PANK3 (Homo sapiens) | 6480464 | Ethyl Methanesulfonate results in decreased expression of PANK3 mRNA | CTD | PMID:23649840 | Pank3 | Rat | fluoxetine | increases expression | ISO | PANK3 (Homo sapiens) | 6480464 | Fluoxetine results in increased expression of PANK3 mRNA | CTD | PMID:37386098 | Pank3 | Rat | folic acid | multiple interactions | ISO | Pank3 (Mus musculus) | 6480464 | [Methionine deficiency co-treated with Choline deficiency co-treated with Folic Acid deficiency] results in increased methylation of PANK3 gene | CTD | PMID:20938992 | Pank3 | Rat | folic acid | decreases expression | ISO | Pank3 (Mus musculus) | 6480464 | Folic Acid results in decreased expression of PANK3 mRNA | CTD | PMID:25629700 | Pank3 | Rat | formaldehyde | decreases expression | ISO | PANK3 (Homo sapiens) | 6480464 | Formaldehyde results in decreased expression of PANK3 mRNA | CTD | PMID:23649840 | Pank3 | Rat | gentamycin | decreases expression | EXP | | 6480464 | Gentamicins results in decreased expression of PANK3 mRNA | CTD | PMID:33387578 | Pank3 | Rat | indole-3-methanol | affects expression | EXP | | 6480464 | indole-3-carbinol affects the expression of PANK3 mRNA | CTD | PMID:21396975 | Pank3 | Rat | isoflavones | increases expression | ISO | PANK3 (Homo sapiens) | 6480464 | Isoflavones results in increased expression of PANK3 mRNA | CTD | PMID:17374662 | Pank3 | Rat | isotretinoin | decreases expression | ISO | PANK3 (Homo sapiens) | 6480464 | Isotretinoin results in decreased expression of PANK3 mRNA | CTD | PMID:20436886 | Pank3 | Rat | L-methionine | multiple interactions | ISO | Pank3 (Mus musculus) | 6480464 | [Methionine deficiency co-treated with Choline deficiency co-treated with Folic Acid deficiency] results in increased methylation of PANK3 gene | CTD | PMID:20938992 | Pank3 | Rat | leflunomide | increases expression | ISO | PANK3 (Homo sapiens) | 6480464 | leflunomide results in increased expression of PANK3 mRNA | CTD | PMID:28988120 | Pank3 | Rat | methyl methanesulfonate | decreases expression | ISO | PANK3 (Homo sapiens) | 6480464 | Methyl Methanesulfonate results in decreased expression of PANK3 mRNA | CTD | PMID:23649840 | Pank3 | Rat | miconazole | increases expression | ISO | Pank3 (Mus musculus) | 6480464 | Miconazole results in increased expression of PANK3 mRNA | CTD | PMID:27462272 | Pank3 | Rat | nickel dichloride | decreases expression | ISO | PANK3 (Homo sapiens) | 6480464 | nickel chloride results in decreased expression of PANK3 mRNA | CTD | PMID:17312168 | Pank3 | Rat | nicotine | increases expression | ISO | PANK3 (Homo sapiens) | 6480464 | Nicotine results in increased expression of PANK3 mRNA | CTD | PMID:16949557 | Pank3 | Rat | ozone | multiple interactions | ISO | PANK3 (Homo sapiens) | 6480464 | [Acrolein co-treated with methacrylaldehyde co-treated with alpha-pinene co-treated with Ozone] results in decreased expression of PANK3 mRNA more ... | CTD | PMID:32699268 | Pank3 | Rat | parathion | increases expression | ISO | Pank3 (Mus musculus) | 6480464 | Parathion results in increased expression of PANK3 mRNA | CTD | PMID:34813904 | Pank3 | Rat | perfluorononanoic acid | decreases expression | ISO | PANK3 (Homo sapiens) | 6480464 | perfluoro-n-nonanoic acid results in decreased expression of PANK3 mRNA | CTD | PMID:32588087 | Pank3 | Rat | perfluorooctane-1-sulfonic acid | multiple interactions | ISO | Pank3 (Mus musculus) | 6480464 | [perfluorooctane sulfonic acid co-treated with Cellulose] results in decreased expression of PANK3 mRNA | CTD | PMID:36331819 | Pank3 | Rat | perfluorooctanoic acid | multiple interactions | EXP | | 6480464 | [Zeranol co-treated with perfluorooctanoic acid] results in decreased expression of PANK3 mRNA | CTD | PMID:35163327 | Pank3 | Rat | phenobarbital | decreases expression | ISO | Pank3 (Mus musculus) | 6480464 | Phenobarbital results in decreased expression of PANK3 mRNA | CTD | PMID:23091169 | Pank3 | Rat | pirinixic acid | increases expression | ISO | Pank3 (Mus musculus) | 6480464 | pirinixic acid results in increased expression of PANK3 mRNA | CTD | PMID:17426115 and PMID:18301758 | Pank3 | Rat | propiconazole | decreases expression | ISO | Pank3 (Mus musculus) | 6480464 | propiconazole results in decreased expression of PANK3 mRNA | CTD | PMID:21278054 | Pank3 | Rat | rotenone | increases expression | ISO | PANK3 (Homo sapiens) | 6480464 | Rotenone results in increased expression of PANK3 mRNA | CTD | PMID:33512557 | Pank3 | Rat | sarin | decreases expression | ISO | PANK3 (Homo sapiens) | 6480464 | Sarin results in decreased expression of PANK3 mRNA | CTD | PMID:19522546 | Pank3 | Rat | sodium arsenate | increases expression | ISO | Pank3 (Mus musculus) | 6480464 | sodium arsenate results in increased expression of PANK3 mRNA | CTD | PMID:21795629 | Pank3 | Rat | sunitinib | increases expression | ISO | PANK3 (Homo sapiens) | 6480464 | Sunitinib results in increased expression of PANK3 mRNA | CTD | PMID:31533062 | Pank3 | Rat | tamibarotene | affects expression | ISO | PANK3 (Homo sapiens) | 6480464 | tamibarotene affects the expression of PANK3 mRNA | CTD | PMID:15498508 | Pank3 | Rat | testosterone | decreases expression | ISO | PANK3 (Homo sapiens) | 6480464 | Testosterone results in decreased expression of PANK3 mRNA | CTD | PMID:33359661 | Pank3 | Rat | tetraphene | decreases expression | ISO | Pank3 (Mus musculus) | 6480464 | benz(a)anthracene results in decreased expression of PANK3 mRNA | CTD | PMID:26377693 | Pank3 | Rat | thioacetamide | increases expression | EXP | | 6480464 | Thioacetamide results in increased expression of PANK3 mRNA | CTD | PMID:34492290 | Pank3 | Rat | titanium dioxide | decreases methylation | ISO | Pank3 (Mus musculus) | 6480464 | titanium dioxide results in decreased methylation of PANK3 gene and titanium dioxide results in decreased methylation of PANK3 promoter | CTD | PMID:35295148 | Pank3 | Rat | triphenyl phosphate | increases expression | EXP | | 6480464 | triphenyl phosphate results in increased expression of PANK3 mRNA | CTD | PMID:30589522 | Pank3 | Rat | triphenyl phosphate | affects expression | ISO | PANK3 (Homo sapiens) | 6480464 | triphenyl phosphate affects the expression of PANK3 mRNA | CTD | PMID:37042841 | Pank3 | Rat | tunicamycin | decreases expression | ISO | Pank3 (Mus musculus) | 6480464 | Tunicamycin results in decreased expression of PANK3 mRNA | CTD | PMID:17127020 | Pank3 | Rat | urethane | increases expression | ISO | PANK3 (Homo sapiens) | 6480464 | Urethane results in increased expression of PANK3 mRNA | CTD | PMID:28818685 | Pank3 | Rat | valproic acid | decreases methylation | ISO | PANK3 (Homo sapiens) | 6480464 | Valproic Acid results in decreased methylation of PANK3 gene | CTD | PMID:29154799 | Pank3 | Rat | valproic acid | affects splicing | EXP | | 6480464 | Valproic Acid affects the splicing of PANK3 mRNA | CTD | PMID:29427782 | Pank3 | Rat | valproic acid | affects expression | ISO | PANK3 (Homo sapiens) | 6480464 | Valproic Acid affects the expression of PANK3 mRNA | CTD | PMID:25979313 | Pank3 | Rat | valproic acid | decreases expression | ISO | PANK3 (Homo sapiens) | 6480464 | Valproic Acid results in decreased expression of PANK3 mRNA | CTD | PMID:23179753 and PMID:29154799 | Pank3 | Rat | vinclozolin | increases expression | EXP | | 6480464 | vinclozolin results in increased expression of PANK3 mRNA | CTD | PMID:23034163 | |