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Gene: Mapk9 (mitogen-activated protein kinase 9) Rattus norvegicus
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Symbol: Mapk9
Name: mitogen-activated protein kinase 9
Description: Exhibits several functions, including ATP binding activity; JUN kinase activity; and cysteine-type endopeptidase activator activity involved in apoptotic process. Involved in several processes, including cellular response to cytokine stimulus; positive regulation of cellular metabolic process; and regulation of protein modification process. Localizes to several cellular components, including the cytosol; mitochondrion; and perikaryon. Used to study type 2 diabetes mellitus. Biomarker of pre-malignant neoplasm. Human ortholog(s) of this gene implicated in colorectal cancer; pancreatic adenocarcinoma; and type 2 diabetes mellitus. Orthologous to human MAPK9 (mitogen-activated protein kinase 9); PARTICIPATES IN c-Jun N-terminal kinases MAPK signaling pathway; FasL mediated signaling pathway; glypican signaling pathway; INTERACTS WITH (S)-nicotine; 1,3-dichloropropan-2-ol; 17beta-estradiol.
Type: protein-coding
RefSeq Status: REVIEWED
Also known as: c-Jun N-terminal kinase 2; MAP kinase 9; MAPK 9; p54-alpha; SAPK; SAPK-alpha; stress activated protein kinase alpha II; stress-activated protein kinase JNK2
Orthologs:
Homo sapiens (human) : MAPK9 (mitogen-activated protein kinase 9)  HGNC  Alliance
Mus musculus (house mouse) : Mapk9 (mitogen-activated protein kinase 9)  MGI  Alliance
Chinchilla lanigera (long-tailed chinchilla) : Mapk9 (mitogen-activated protein kinase 9)
Pan paniscus (bonobo/pygmy chimpanzee) : MAPK9 (mitogen-activated protein kinase 9)
Canis lupus familiaris (dog) : MAPK9 (mitogen-activated protein kinase 9)
Ictidomys tridecemlineatus (thirteen-lined ground squirrel) : Mapk9 (mitogen-activated protein kinase 9)
Sus scrofa (pig) : MAPK9 (mitogen-activated protein kinase 9)
more info ...
Latest Assembly: Rnor_6.0 - RGSC Genome Assembly v6.0
Position:
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Rnor_6.01035,333,859 - 35,374,364 (+)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl1035,333,859 - 35,374,355 (+)Ensembl
Rnor_5.01035,105,633 - 35,147,516 (+)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.41035,353,486 - 35,384,319 (+)NCBIRGSC3.4rn4RGSC3.4
RGSC_v3.11035,354,534 - 35,385,368 (+)NCBI
Celera1033,525,368 - 33,565,857 (+)NCBICelera
Cytogenetic Map10q21NCBI
JBrowse: View Region in Genome Browser (JBrowse)
Model


Disease Annotations
Gene-Chemical Interaction Annotations
Gene Ontology Annotations
Molecular Pathway Annotations
References - curated
References - uncurated

Genomics

Candidate Gene Status
Comparative Map Data
QTLs in Region (Rnor_6.0)
miRNA Target Status

Expression

RNA-SEQ Expression

Sequence

Nucleotide Sequences
Protein Sequences
Transcriptome
Promoters

Strain Variation

Strain Sequence Variants (Rnor 6.0)

Additional Information

External Database Links
Nomenclature History
RGD Curation Notes
 
More on Mapk9
Alliance Gene
NCBI Gene
Ensembl Gene
JBrowse: rn5 rn6
NCBI Genome Data Viewer

RGD Object Information
RGD ID: 628847
Created: 2003-02-27
Species: Rattus norvegicus
Last Modified: 2019-11-27
Status: ACTIVE



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RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.