Gene: Polr2a (RNA polymerase II subunit A) Rattus norvegicus
Symbol: Polr2a
Name: RNA polymerase II subunit A
Description: ENCODES a protein that exhibits core promoter binding (ortholog); DNA binding (ortholog); promoter-specific chromatin binding (ortholog); INVOLVED IN cellular response to oxygen levels; response to organic cyclic compound; DNA-templated transcription, termination (ortholog); PARTICIPATES IN RNA polymerase II transcription pathway; Huntington's disease pathway; purine metabolic pathway; ASSOCIATED WITH Infarction; Huntington's disease (ortholog); Weissenbacher-Zweymuller syndrome (ortholog); FOUND IN nucleus; nuclear euchromatin (ortholog); Prp19 complex (ortholog); INTERACTS WITH 2,4-dinitrotoluene; 3H-1,2-dithiole-3-thione; benzo[a]pyrene
Type: protein-coding
RefSeq Status: MODEL
Also known as: DNA-directed RNA polymerase II subunit RPB1; Polr2a_mapped; Polymerase (RNA II (DNA directed), large polypeptide; polymerase (RNA) II (DNA directed) polypeptide A; polymerase (RNA) II (DNA directed) polypeptide A (mapped); polymerase (RNA) II (DNA directed) polypeptide A, 220kDa; polymerase (RNA) II subunit A; Rpo2-1
Homo sapiens (human) : POLR2A (RNA polymerase II subunit A)  HGNC  Alliance
Mus musculus (house mouse) : Polr2a (polymerase (RNA) II (DNA directed) polypeptide A)  MGI  Alliance
Chinchilla lanigera (long-tailed chinchilla) : Polr2a (RNA polymerase II subunit A)
Pan paniscus (bonobo/pygmy chimpanzee) : POLR2A (RNA polymerase II subunit A)
Canis lupus familiaris (dog) : POLR2A (RNA polymerase II subunit A)
Ictidomys tridecemlineatus (thirteen-lined ground squirrel) : Polr2a (RNA polymerase II subunit A)
Sus scrofa (pig) : POLR2A (RNA polymerase II subunit A)
more info ...
Latest Assembly: Rnor_6.0 - RGSC Genome Assembly v6.0
Rat AssemblyChrPosition (strand)SourceGenome Browsers
Rnor_6.01056,339,277 - 56,364,888 (-)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_5.01056,084,677 - 56,110,778 (-)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.41056,552,872 - 56,579,172 (-)NCBIRGSC3.4rn4RGSC3.4
Celera1053,606,814 - 53,632,373 (-)NCBICelera
Cytogenetic Map10q24NCBI
JBrowse: View Region in Genome Browser (JBrowse)

Disease Annotations
Gene-Chemical Interaction Annotations
Gene Ontology Annotations
Molecular Pathway Annotations
References - curated
References - uncurated
RGD Disease Portals


Comparative Map Data
Position Markers
QTLs in Region (Rnor_6.0)
miRNA Target Status


Nucleotide Sequences
Protein Sequences

Strain Variation

Strain Sequence Variants (Rnor 5.0)
Damaging Variants

Additional Information

External Database Links
Nomenclature History
RGD Curation Notes
More on Polr2a
Alliance Gene
Ensembl Gene
JBrowse: rn5 rn6
NCBI Genome Data Viewer

RGD Object Information
RGD ID: 1587326
Created: 2006-11-19
Species: Rattus norvegicus
Last Modified: 2019-01-30
Status: ACTIVE