Mgat1 (alpha-1,3-mannosyl-glycoprotein 2-beta-N-acetylglucosaminyltransferase) - Rat Genome Database

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Gene: Mgat1 (alpha-1,3-mannosyl-glycoprotein 2-beta-N-acetylglucosaminyltransferase) Rattus norvegicus
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Symbol: Mgat1
Name: alpha-1,3-mannosyl-glycoprotein 2-beta-N-acetylglucosaminyltransferase
RGD ID: 620097
Description: Predicted to have alpha-1,3-mannosylglycoprotein 2-beta-N-acetylglucosaminyltransferase activity and manganese ion binding activity. Predicted to be involved in UDP-N-acetylglucosamine catabolic process; in utero embryonic development; and protein N-linked glycosylation via asparagine. Predicted to localize to Golgi membrane. Orthologous to human MGAT1 (alpha-1,3-mannosyl-glycoprotein 2-beta-N-acetylglucosaminyltransferase); PARTICIPATES IN N-linked glycan biosynthetic pathway; INTERACTS WITH (+)-schisandrin B; 1,2,4-trimethylbenzene; 2,4-dinitrotoluene.
Type: protein-coding
RefSeq Status: PROVISIONAL
Also known as: glcNAc-T I; GNT-I; mannoside acetylglucosaminyltransferase 1; mannosyl (alpha-1,3-)-glycoprotein beta-1,2-N-acetylglucosaminyltransferase; MGAT1 gene for N-acetylglucosaminyltransferase; N-acetylglucosaminyltransferase I; N-glycosyl-oligosaccharide-glycoprotein N-acetylglucosaminyltransferase I
RGD Orthologs
Human
Mouse
Chinchilla
Bonobo
Dog
Squirrel
Pig
Green Monkey
Naked Mole-Rat
Alliance Genes
More Info more info ...
Latest Assembly: Rnor_6.0 - RGSC Genome Assembly v6.0
Position:
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
mRatBN7.21033,563,642 - 33,582,718 (+)NCBI
Rnor_6.0 Ensembl1034,519,790 - 34,537,210 (+)EnsemblRnor6.0rn6Rnor6.0
Rnor_6.01034,518,392 - 34,537,214 (+)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_5.01034,294,712 - 34,313,531 (+)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.41034,706,908 - 34,724,328 (+)NCBIRGSC3.4rn4RGSC3.4
RGSC_v3.11034,707,956 - 34,725,377 (+)NCBI
Celera1032,944,950 - 32,962,376 (+)NCBICelera
Cytogenetic Map10q21NCBI
JBrowse: View Region in Genome Browser (JBrowse)
Model


Disease Annotations     Click to see Annotation Detail View
COVID-19  (ISO)

Gene Ontology Annotations     Click to see Annotation Detail View

Cellular Component

Molecular Pathway Annotations     Click to see Annotation Detail View
References

Additional References at PubMed
PMID:1421759   PMID:1702225   PMID:8290590   PMID:9781684   PMID:12878032   PMID:12913295   PMID:15489334   PMID:19199708   PMID:19946888   PMID:20378551   PMID:23376485   PMID:23533145  
PMID:24769233  


Genomics

Comparative Map Data
Mgat1
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
mRatBN7.21033,563,642 - 33,582,718 (+)NCBI
Rnor_6.0 Ensembl1034,519,790 - 34,537,210 (+)EnsemblRnor6.0rn6Rnor6.0
Rnor_6.01034,518,392 - 34,537,214 (+)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_5.01034,294,712 - 34,313,531 (+)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.41034,706,908 - 34,724,328 (+)NCBIRGSC3.4rn4RGSC3.4
RGSC_v3.11034,707,956 - 34,725,377 (+)NCBI
Celera1032,944,950 - 32,962,376 (+)NCBICelera
Cytogenetic Map10q21NCBI
MGAT1
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh38.p13 Ensembl5180,784,782 - 180,815,652 (-)EnsemblGRCh38hg38GRCh38
GRCh38.p13 Ensembl5180,784,780 - 180,815,652 (-)EnsemblGRCh38hg38GRCh38
GRCh385180,784,780 - 180,815,616 (-)NCBIGRCh38GRCh38hg38GRCh38
GRCh375180,211,780 - 180,242,616 (-)NCBIGRCh37GRCh37hg19GRCh37
Build 365180,150,149 - 180,162,654 (-)NCBINCBI36hg18NCBI36
Build 345180,150,153 - 180,162,654NCBI
Celera5175,841,463 - 175,861,059 (-)NCBI
Cytogenetic Map5q35.3NCBI
HuRef5174,942,953 - 174,962,572 (-)NCBIHuRef
CHM1_15179,649,941 - 179,669,538 (-)NCBICHM1_1
Mgat1
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm391149,135,018 - 49,153,854 (+)NCBIGRCm39mm39
GRCm39 Ensembl1149,135,018 - 49,153,857 (+)Ensembl
GRCm381149,244,191 - 49,263,027 (+)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl1149,244,191 - 49,263,030 (+)EnsemblGRCm38mm10GRCm38
MGSCv371149,057,693 - 49,076,529 (+)NCBIGRCm37mm9NCBIm37
MGSCv361149,087,669 - 49,106,450 (+)NCBImm8
Celera1153,806,759 - 53,825,547 (+)NCBICelera
Cytogenetic Map11B1.2NCBI
cM Map1129.27NCBI
Mgat1
(Chinchilla lanigera - long-tailed chinchilla)
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0 EnsemblNW_004955530437,008 - 452,289 (+)EnsemblChiLan1.0
ChiLan1.0NW_004955530436,518 - 452,296 (+)NCBIChiLan1.0ChiLan1.0
MGAT1
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
PanPan1.15183,292,153 - 183,317,334 (-)NCBIpanpan1.1PanPan1.1panPan2
PanPan1.1 Ensembl5183,293,237 - 183,294,574 (-)Ensemblpanpan1.1panPan2
Mhudiblu_PPA_v05175,978,425 - 176,003,620 (-)NCBIMhudiblu_PPA_v0panPan3
MGAT1
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.111114,587 - 129,014 (-)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
CanFam3.1 Ensembl11115,631 - 129,091 (-)EnsemblCanFam3.1canFam3CanFam3.1
Dog10K_Boxer_Tasha11172,388 - 187,101 (-)NCBI
Mgat1
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HiC_Itri_2NW_024407213118,240,717 - 118,260,848 (+)NCBI
SpeTri2.0NW_004936826344,452 - 364,929 (-)NCBISpeTri2.0SpeTri2.0SpeTri2.0
MGAT1
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 Ensembl257,900,216 - 57,920,977 (+)EnsemblSscrofa11.1susScr11Sscrofa11.1
Sscrofa11.1257,849,185 - 57,920,410 (+)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
Sscrofa10.22159,732,009 - 159,753,282 (+)NCBISscrofa10.2Sscrofa10.2susScr3
MGAT1
(Chlorocebus sabaeus - African green monkey)
Vervet AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.12382,525,527 - 82,527,753 (-)NCBI
ChlSab1.1 Ensembl2382,507,525 - 82,508,862 (-)NCBI
Mgat1
(Heterocephalus glaber - naked mole-rat)
Molerat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla 1.0NW_00462481111,050,378 - 11,069,734 (-)NCBI

Position Markers
BF392858  
Rat AssemblyChrPosition (strand)SourceJBrowse
Rnor_6.01034,523,476 - 34,523,712NCBIRnor6.0
Rnor_5.01034,299,793 - 34,300,029UniSTSRnor5.0
RGSC_v3.41034,710,594 - 34,710,830UniSTSRGSC3.4
Celera1032,948,636 - 32,948,872UniSTS
RH 3.4 Map10367.9UniSTS
Cytogenetic Map10q21UniSTS


QTLs in Region (Rnor_6.0)
The following QTLs overlap with this region.    Full Report CSV TAB Printer Gviewer
RGD IDSymbolNameLODP ValueTraitSub TraitChrStartStopSpecies
2293680Bss40Bone structure and strength QTL 405.660.0001femur strength trait (VT:0010010)femur total energy absorbed before break (CMO:0001677)10135538813Rat
634327Hc4Hypercalciuria QTL 42.4urine calcium amount (VT:0002985)urine calcium excretion rate (CMO:0000763)10138594330Rat
7411611Foco17Food consumption QTL 1718.70.001eating behavior trait (VT:0001431)feed conversion ratio (CMO:0001312)10142669970Rat
10401803Kidm50Kidney mass QTL 50kidney mass (VT:0002707)both kidneys wet weight (CMO:0000085)10144902893Rat
631554Bp133Blood pressure QTL 1330.005arterial blood pressure trait (VT:2000000)systolic blood pressure (CMO:0000004)1076442166221621Rat
2298544Neuinf9Neuroinflammation QTL 94.6nervous system integrity trait (VT:0010566)spinal cord complement component 1, q subcomponent, B chain mRNA level (CMO:0002126)10587753664401490Rat
8662860Vetf10Vascular elastic tissue fragility QTL 10artery integrity trait (VT:0010639)number of ruptures of the internal elastic lamina of the abdominal aorta and iliac arteries (CMO:0002562)10622909575983805Rat
631660Hcar1Hepatocarcinoma resistance QTL 13.40.0001liver integrity trait (VT:0010547)volume of individual liver tumorous lesion (CMO:0001078)10622928936185929Rat
61427Cia16Collagen induced arthritis QTL 163.2joint integrity trait (VT:0010548)joint inflammation composite score (CMO:0000919)10642907599492409Rat
1578761Stresp21Stress response QTL 213.3thymus mass (VT:0004954)thymus wet weight (CMO:0000855)10752145052521450Rat
2303118Mamtr7Mammary tumor resistance QTL 70.003mammary gland integrity trait (VT:0010552)mammary tumor growth rate (CMO:0000344)109841807108540162Rat
9590310Scort19Serum corticosterone level QTL 196.30.001blood corticosterone amount (VT:0005345)plasma corticosterone level (CMO:0001173)101263951357639513Rat
9590268Scort13Serum corticosterone level QTL 133.260.001blood corticosterone amount (VT:0005345)plasma corticosterone level (CMO:0001173)101263951357639513Rat
9589136Insul27Insulin level QTL 2710.460.001blood insulin amount (VT:0001560)plasma insulin level (CMO:0000342)101263951357639513Rat
2301967Cm73Cardiac mass QTL 734.55heart left ventricle mass (VT:0007031)heart left ventricle weight to body weight ratio (CMO:0000530)101482789492423564Rat
631268Cia21Collagen induced arthritis QTL 213.1joint integrity trait (VT:0010548)joint inflammation composite score (CMO:0000919)1014827894107857673Rat
2316949Gluco60Glucose level QTL 603.7blood glucose amount (VT:0000188)blood glucose level (CMO:0000046)1014827894110992275Rat
1354587Kidm21Kidney mass QTL 213.3kidney mass (VT:0002707)right kidney wet weight (CMO:0000082)101537547462469074Rat
631564Apr3Acute phase response QTL 33.9blood interleukin-6 amount (VT:0008595)plasma interleukin-6 level (CMO:0001927)101646873661468736Rat
6893350Bw99Body weight QTL 990.870.16body mass (VT:0001259)body weight (CMO:0000012)11712154262121542Rat
6893352Bw100Body weight QTL 1000.330.6body mass (VT:0001259)body weight (CMO:0000012)11712154262121542Rat
631532Cm50Cardiac mass QTL 506.6heart mass (VT:0007028)calculated heart weight (CMO:0000073)101824639453637634Rat
1598852Anxrr19Anxiety related response QTL 195.07body movement coordination trait (VT:0005424)number of rearing movements in an experimental apparatus (CMO:0001752)101940281464402814Rat
1554317Bmd4Bone mineral density QTL 49.40.0001lumbar vertebra mineral mass (VT:0010511)volumetric bone mineral density (CMO:0001553)1020170031102897474Rat
70223Bp57Blood pressure QTL 575arterial blood pressure trait (VT:2000000)systolic blood pressure (CMO:0000004)102152390683549467Rat
70188BpQTLcluster1Blood pressure QTL cluster 14.864arterial blood pressure trait (VT:2000000)diastolic blood pressure (CMO:0000005)12152390690312401Rat
70188BpQTLcluster1Blood pressure QTL cluster 14.864arterial blood pressure trait (VT:2000000)systolic blood pressure (CMO:0000004)12152390690312401Rat
70188BpQTLcluster1Blood pressure QTL cluster 14.864arterial blood pressure trait (VT:2000000)mean arterial blood pressure (CMO:0000009)12152390690312401Rat
70188BpQTLcluster1Blood pressure QTL cluster 14.864arterial blood pressure trait (VT:2000000)pulse pressure (CMO:0000292)12152390690312401Rat
70198BpQTLcluster9Blood pressure QTL cluster 92.94arterial blood pressure trait (VT:2000000)mean arterial blood pressure (CMO:0000009)102152390690312401Rat
1581497Esta1Estrogen-induced thymic atrophy QTL 1thymus mass (VT:0004954)thymus wet weight (CMO:0000855)102170776664648311Rat
631531Iresp2Immunoglobin response QTL26.3blood immunoglobulin E amount (VT:0002492)serum total immunoglobulin E level (CMO:0001542)102240281738204229Rat
724556Pur2Proteinuria QTL 25.5urine protein amount (VT:0005160)urine protein level (CMO:0000591)102290149793886300Rat
1331762Rf40Renal function QTL 403.873kidney blood vessel physiology trait (VT:0100012)absolute change in renal vascular resistance (CMO:0001900)102386101566539843Rat
1331791Cm31Cardiac mass QTL 313.84606heart mass (VT:0007028)heart wet weight (CMO:0000069)1023861015112626471Rat
631267Cia20Collagen induced arthritis QTL 203.2joint integrity trait (VT:0010548)joint inflammation composite score (CMO:0000919)1024483076107857673Rat
61325Aia5Adjuvant induced arthritis QTL 50.01joint integrity trait (VT:0010548)joint inflammation composite score (CMO:0000919)1024483076107857673Rat
61354Pia10Pristane induced arthritis QTL 100.01joint integrity trait (VT:0010548)joint inflammation composite score (CMO:0000919)1024483076107857673Rat
634329Pia15Pristane induced arthritis QTL 153.1joint integrity trait (VT:0010548)joint inflammation composite score (CMO:0000919)102488408447487910Rat
70224Eae3Experimental allergic encephalomyelitis QTL 34.1nervous system integrity trait (VT:0010566)experimental autoimmune encephalomyelitis incidence/prevalence measurement (CMO:0001046)102723753064648311Rat
1298069Bp168Blood pressure QTL 1685.5blood pressure trait (VT:0000183)systolic blood pressure (CMO:0000004)1027237530101482600Rat
631542Bp82Blood pressure QTL 826.8arterial blood pressure trait (VT:2000000)systolic blood pressure (CMO:0000004)1027237530102427718Rat
2300171Bmd58Bone mineral density QTL 584.90.0001lumbar vertebra mineral mass (VT:0010511)volumetric bone mineral density (CMO:0001553)102878928073789280Rat
1600371Mcs21Mammary carcinoma susceptibility QTL 213mammary gland integrity trait (VT:0010552)mammary tumor growth rate (CMO:0000344)103002135454057745Rat
2292441Bp308Blood pressure QTL 308arterial blood pressure trait (VT:2000000)mean arterial blood pressure (CMO:0000009)103009990975099909Rat
10402859Bp381Blood pressure QTL 3810.002arterial blood pressure trait (VT:2000000)mean arterial blood pressure (CMO:0000009)103009990975099909Rat
724527Bp148Blood pressure QTL 1480.0001arterial blood pressure trait (VT:2000000)mean arterial blood pressure (CMO:0000009)103098380575983805Rat
1576311Pia26Pristane induced arthritis QTL 26joint integrity trait (VT:0010548)joint inflammation composite score (CMO:0000919)103191939778343192Rat
1578779Tcas10Tongue tumor susceptibility QTL 103.12tongue integrity trait (VT:0010553)number of squamous cell tumors of the tongue with diameter greater than 3 mm (CMO:0001950)103317903078179030Rat
631557Bp136Blood pressure QTL 1360.003arterial blood pressure trait (VT:2000000)systolic blood pressure (CMO:0000004)103334319278343192Rat

miRNA Target Status

Predicted Target Of
Summary Value
Count of predictions:267
Count of miRNA genes:179
Interacting mature miRNAs:211
Transcripts:ENSRNOT00000052360
Prediction methods:Microtar, Miranda, Rnahybrid, Targetscan
Result types:miRGate_prediction

The detailed report is available here: Full Report CSV TAB Printer

miRNA Target Status data imported from miRGate (http://mirgate.bioinfo.cnio.es/).
For more information about miRGate, see PMID:25858286 or access the full paper here.


Expression


RNA-SEQ Expression
High: > 1000 TPM value   Medium: Between 11 and 1000 TPM
Low: Between 0.5 and 10 TPM   Below Cutoff: < 0.5 TPM

alimentary part of gastrointestinal system circulatory system endocrine system exocrine system hemolymphoid system hepatobiliary system integumental system musculoskeletal system nervous system renal system reproductive system respiratory system appendage
High
Medium 3 43 57 41 19 41 8 11 74 35 41 11 8
Low
Below cutoff

Sequence

Nucleotide Sequences
RefSeq Transcripts NM_030861 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_006246182 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_006246183 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_006246184 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_006246185 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_008767715 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_039086928 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
GenBank Nucleotide AB012874 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AB012875 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AB012876 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AB012877 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AB012878 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AB100423 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AB100424 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AB100425 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AC133273 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  BC074010 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  CH473948 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  D16302 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  JACYVU010000219 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles

Reference Sequences
RefSeq Acc Id: ENSRNOT00000052360   ⟹   ENSRNOP00000044560
RefSeq Status:
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
Rnor_6.0 Ensembl1034,519,790 - 34,537,210 (+)Ensembl
RefSeq Acc Id: ENSRNOT00000085832   ⟹   ENSRNOP00000068827
RefSeq Status:
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
Rnor_6.0 Ensembl1034,524,845 - 34,537,208 (+)Ensembl
RefSeq Acc Id: NM_030861   ⟹   NP_110488
RefSeq Status: PROVISIONAL
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.21033,565,293 - 33,582,714 (+)NCBI
Rnor_6.01034,519,790 - 34,537,210 (+)NCBI
Rnor_5.01034,294,712 - 34,313,531 (+)NCBI
RGSC_v3.41034,706,908 - 34,724,328 (+)RGD
Celera1032,944,950 - 32,962,376 (+)RGD
Sequence:
RefSeq Acc Id: XM_006246182   ⟹   XP_006246244
RefSeq Status:
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.21033,563,867 - 33,582,718 (+)NCBI
Rnor_6.01034,518,392 - 34,537,214 (+)NCBI
Rnor_5.01034,294,712 - 34,313,531 (+)NCBI
Sequence:
RefSeq Acc Id: XM_006246183   ⟹   XP_006246245
RefSeq Status:
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.21033,569,786 - 33,582,718 (+)NCBI
Rnor_6.01034,524,220 - 34,537,214 (+)NCBI
Rnor_5.01034,294,712 - 34,313,531 (+)NCBI
Sequence:
RefSeq Acc Id: XM_006246184   ⟹   XP_006246246
RefSeq Status:
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.21033,569,785 - 33,582,718 (+)NCBI
Rnor_6.01034,524,220 - 34,537,214 (+)NCBI
Rnor_5.01034,294,712 - 34,313,531 (+)NCBI
Sequence:
RefSeq Acc Id: XM_006246185   ⟹   XP_006246247
RefSeq Status:
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.21033,563,867 - 33,582,718 (+)NCBI
Rnor_6.01034,518,392 - 34,537,214 (+)NCBI
Rnor_5.01034,294,712 - 34,313,531 (+)NCBI
Sequence:
RefSeq Acc Id: XM_008767715   ⟹   XP_008765937
RefSeq Status:
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
Rnor_6.01034,518,518 - 34,537,214 (+)NCBI
Sequence:
RefSeq Acc Id: XM_039086928   ⟹   XP_038942856
RefSeq Status:
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.21033,563,642 - 33,582,718 (+)NCBI
Reference Sequences
RefSeq Acc Id: NP_110488   ⟸   NM_030861
- UniProtKB: Q09325 (UniProtKB/Swiss-Prot)
- Sequence:
RefSeq Acc Id: XP_006246247   ⟸   XM_006246185
- Peptide Label: isoform X1
- UniProtKB: Q09325 (UniProtKB/Swiss-Prot)
- Sequence:
RefSeq Acc Id: XP_006246244   ⟸   XM_006246182
- Peptide Label: isoform X1
- UniProtKB: Q09325 (UniProtKB/Swiss-Prot)
- Sequence:
RefSeq Acc Id: XP_006246246   ⟸   XM_006246184
- Peptide Label: isoform X1
- UniProtKB: Q09325 (UniProtKB/Swiss-Prot)
- Sequence:
RefSeq Acc Id: XP_006246245   ⟸   XM_006246183
- Peptide Label: isoform X1
- UniProtKB: Q09325 (UniProtKB/Swiss-Prot)
- Sequence:
RefSeq Acc Id: XP_008765937   ⟸   XM_008767715
- Peptide Label: isoform X1
- Sequence:
RefSeq Acc Id: ENSRNOP00000068827   ⟸   ENSRNOT00000085832
RefSeq Acc Id: ENSRNOP00000044560   ⟸   ENSRNOT00000052360
RefSeq Acc Id: XP_038942856   ⟸   XM_039086928
- Peptide Label: isoform X1

Transcriptome

eQTL   View at Phenogen
WGCNA   View at Phenogen
Tissue/Strain Expression   View at Phenogen

Promoters
RGD ID:13697156
Promoter ID:EPDNEW_R7664
Type:initiation region
Name:Mgat1_1
Description:mannosyl (alpha-1,3-)-glycoprotein beta-1,2-N-acetylglucosaminyltransferase
SO ACC ID:SO:0000170
Source:EPDNEW (Eukaryotic Promoter Database, http://epd.vital-it.ch/)
Experiment Methods:Single-end sequencing.
Position:
Rat AssemblyChrPosition (strand)Source
Rnor_6.01034,524,837 - 34,524,897EPDNEW

Strain Variation

Strain Sequence Variants (Rnor 6.0)
ACI/EurMcwi (MCW)
Visual CSV TAB Printer
Sequenced By: Medical College of Wisconsin (Dr. Howard Jacob)
Platform: Illumina HiSeq 2000
Secondary Analysis: BWA v0.7.7 and GATK v3.2-2
Breeder: Medical College of Wisconsin
Description: Provided by the Medical College of Wisconsin (Dr. Howard Jacob)
ACI/EurMcwi (RGD)
Visual CSV TAB Printer
Platform: Illumina HiSeq 2000
Secondary Analysis: BWA mem 0.7.15, GATK v.3.6-0
Description: Sequences from Atanur et al and Hermsen et al realigned to the Rnor 6.0 assembly and reanalyzed by RGD
ACI/N (MCW)
Visual CSV TAB Printer
Sequenced By: Royal Netherland Academy of Arts and Sciences (Dr. Edwin Cuppen)
Max Delbruck Center for Molecular Medicine (Dr. Norbert Huebner)
Platform: SOLiD 4 and 5500
Secondary Analysis: liftOver (Batch Coordinate Conversion)--genome.ucsc.edu
Breeder: National Institutes of Health
Description: Founder strain for the heterogeneous stock (HS) rat population; SNPs from the RGSC 3.4 assembly were "lifted over" from RGSC 3.4 to Rnor 5.0 and from Rnor 5.0 to Rnor 6.0; Provided by Medical College of Wisconsin
BBDP/Wor (RGD)
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Platform: Illumina HiSeq 2000
Secondary Analysis: BWA mem 0.7.15, GATK v.3.6-0
Description: Sequences from Atanur et al and Hermsen et al realigned to the Rnor 6.0 assembly and reanalyzed by RGD
BN/SsN (MCW)
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Sequenced By: Royal Netherland Academy of Arts and Sciences (Dr. Edwin Cuppen)
Max Delbruck Center for Molecular Medicine (Dr. Norbert Huebner)
Platform: SOLiD 4 and 5500
Secondary Analysis: liftOver (Batch Coordinate Conversion)--genome.ucsc.edu
Breeder: National Institutes of Health
Description: Founder strain for the heterogeneous stock (HS) rat population; SNPs from the RGSC 3.4 assembly were "lifted over" from RGSC 3.4 to Rnor 5.0 and from Rnor 5.0 to Rnor 6.0; Provided by Medical College of Wisconsin
Buf/N (MCW)
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Sequenced By: Royal Netherland Academy of Arts and Sciences (Dr. Edwin Cuppen)
Max Delbruck Center for Molecular Medicine (Dr. Norbert Huebner)
Platform: SOLiD 4 and 5500
Secondary Analysis: liftOver (Batch Coordinate Conversion)--genome.ucsc.edu
Breeder: National Institutes of Health
Description: Founder strain for the heterogeneous stock (HS) rat population; SNPs from the RGSC 3.4 assembly were "lifted over" from RGSC 3.4 to Rnor 5.0 and from Rnor 5.0 to Rnor 6.0; Provided by Medical College of Wisconsin
COP/CrCrl (MCW & UW)
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Sequenced By: Medical College of Wisconsin (Dr. Howard Jacob)
University of Wisconsin (Dr. James Shull)
Platform: Illumina HiSeq 2000
Secondary Analysis: BWA v0.7.7 and GATK v3.2-2
Breeder: Charles River Laboratories
Description: Provided by the Medical College of Wisconsin (Dr. Howard Jacob) and UW Madison (Dr. James Shull)
F344/NCrl (RGD)
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Platform: Illumina HiSeq 2000
Secondary Analysis: BWA mem 0.7.15, GATK v.3.6-0
Description: Sequences from Atanur et al and Hermsen et al realigned to the Rnor 6.0 assembly and reanalyzed by RGD
F344/NRrrc (MCW)
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Sequenced By: Royal Netherland Academy of Arts and Sciences (Dr. Edwin Cuppen)
Max Delbruck Center for Molecular Medicine (Dr. Norbert Huebner)
Platform: SOLiD 4 and 5500
Secondary Analysis: liftOver (Batch Coordinate Conversion)--genome.ucsc.edu
Breeder: National Institutes of Health
Description: Founder strain for the heterogeneous stock (HS) rat population; SNPs from the RGSC 3.4 assembly were "lifted over" from RGSC 3.4 to Rnor 5.0 and from Rnor 5.0 to Rnor 6.0; Provided by Medical College of Wisconsin
FHH/EurMcwi (MCW)
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Sequenced By: Medical College of Wisconsin (Dr. Howard Jacob)
Platform: Illumina HiSeq 2000
Secondary Analysis: BWA v0.7.7 and GATK v3.2-2
Breeder: Medical College of Wisconsin
Description: Provided by the Medical College of Wisconsin (Dr. Howard Jacob)
FHH/EurMcwi (RGD)
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Platform: Illumina HiSeq 2000
Secondary Analysis: BWA mem 0.7.15, GATK v.3.6-0
Description: Sequences from Atanur et al and Hermsen et al realigned to the Rnor 6.0 assembly and reanalyzed by RGD
FHL/EurMcwi (MCW)
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Sequenced By: Medical College of Wisconsin (Dr. Howard Jacob)
Platform: Illumina HiSeq 2000
Secondary Analysis: BWA v0.7.7 and GATK v3.2-2
Breeder: Medical College of Wisconsin
Description: Provided by the Medical College of Wisconsin (Dr. Howard Jacob)
FHL/EurMcwi (RGD)
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Platform: Illumina HiSeq 2000
Secondary Analysis: BWA mem 0.7.15, GATK v.3.6-0
Description: Sequences from Atanur et al and Hermsen et al realigned to the Rnor 6.0 assembly and reanalyzed by RGD
GH/OmrMcwi (MCW)
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Sequenced By: Medical College of Wisconsin (Dr. Howard Jacob)
Platform: Illumina HiSeq 2000
Secondary Analysis: BWA v0.7.7 and GATK v3.2-2
Breeder: Medical College of Wisconsin
Description: Provided by the Medical College of Wisconsin (Dr. Howard Jacob)
GK/Ox (RGD)
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Platform: Illumina HiSeq 2000
Secondary Analysis: BWA mem 0.7.15, GATK v.3.6-0
Description: Sequences from Atanur et al and Hermsen et al realigned to the Rnor 6.0 assembly and reanalyzed by RGD
LE/Stm (RGD)
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Platform: Illumina HiSeq 2000
Secondary Analysis: BWA mem 0.7.15, GATK v.3.6-0
Description: Sequences from Atanur et al and Hermsen et al realigned to the Rnor 6.0 assembly and reanalyzed by RGD
LEW/Crl (RGD)
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Platform: Illumina HiSeq 2000
Secondary Analysis: BWA mem 0.7.15, GATK v.3.6-0
Description: Sequences from Atanur et al and Hermsen et al realigned to the Rnor 6.0 assembly and reanalyzed by RGD
LEW/NCrlBR (RGD)
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Platform: Illumina HiSeq 2000
Secondary Analysis: BWA mem 0.7.15, GATK v.3.6-0
Description: Sequences from Atanur et al and Hermsen et al realigned to the Rnor 6.0 assembly and reanalyzed by RGD
LH/MavRrrc (RGD)
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Platform: Illumina HiSeq 2000
Secondary Analysis: BWA mem 0.7.15, GATK v.3.6-0
Description: Sequences from Atanur et al and Hermsen et al realigned to the Rnor 6.0 assembly and reanalyzed by RGD
LL/MavRrrc (RGD)
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Platform: Illumina HiSeq 2000
Secondary Analysis: BWA mem 0.7.15, GATK v.3.6-0
Description: Sequences from Atanur et al and Hermsen et al realigned to the Rnor 6.0 assembly and reanalyzed by RGD
LN/MavRrrc (RGD)
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Platform: Illumina HiSeq 2000
Secondary Analysis: BWA mem 0.7.15, GATK v.3.6-0
Description: Sequences from Atanur et al and Hermsen et al realigned to the Rnor 6.0 assembly and reanalyzed by RGD
M520/N (MCW)
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Sequenced By: Royal Netherland Academy of Arts and Sciences (Dr. Edwin Cuppen)
Max Delbruck Center for Molecular Medicine (Dr. Norbert Huebner)
Platform: SOLiD 4 and 5500
Secondary Analysis: liftOver (Batch Coordinate Conversion)--genome.ucsc.edu
Breeder: National Institutes of Health
Description: Founder strain for the heterogeneous stock (HS) rat population; SNPs from the RGSC 3.4 assembly were "lifted over" from RGSC 3.4 to Rnor 5.0 and from Rnor 5.0 to Rnor 6.0; Provided by Medical College of Wisconsin
MHS/Gib (RGD)
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Platform: Illumina HiSeq 2000
Secondary Analysis: BWA mem 0.7.15, GATK v.3.6-0
Description: Sequences from Atanur et al and Hermsen et al realigned to the Rnor 6.0 assembly and reanalyzed by RGD
MNS/Gib (RGD)
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Platform: Illumina HiSeq 2000
Secondary Analysis: BWA mem 0.7.15, GATK v.3.6-0
Description: Sequences from Atanur et al and Hermsen et al realigned to the Rnor 6.0 assembly and reanalyzed by RGD
MR/N (MCW)
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Sequenced By: Royal Netherland Academy of Arts and Sciences (Dr. Edwin Cuppen)
Max Delbruck Center for Molecular Medicine (Dr. Norbert Huebner)
Platform: SOLiD 4 and 5500
Secondary Analysis: liftOver (Batch Coordinate Conversion)--genome.ucsc.edu
Breeder: National Institutes of Health
Description: Founder strain for the heterogeneous stock (HS) rat population; SNPs from the RGSC 3.4 assembly were "lifted over" from RGSC 3.4 to Rnor 5.0 and from Rnor 5.0 to Rnor 6.0; Provided by Medical College of Wisconsin
SBH/Ygl (MCW)
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Sequenced By: Medical College of Wisconsin (Dr. Howard Jacob)
Platform: Illumina HiSeq 2000
Secondary Analysis: BWA v0.7.7 and GATK v3.2-2
Breeder: Medical College of Wisconsin
Description: SBH/Ygl sequenced by MCW
SBH/Ygl (RGD)
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Platform: Illumina HiSeq 2000
Secondary Analysis: BWA mem 0.7.15, GATK v.3.6-0
Description: Sequences from Atanur et al and Hermsen et al realigned to the Rnor 6.0 assembly and reanalyzed by RGD
SBN/Ygl (MCW)
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Sequenced By: Medical College of Wisconsin (Dr. Howard Jacob)
Platform: Illumina HiSeq 2000
Secondary Analysis: BWA v0.7.7 and GATK v3.2-2
Breeder: Medical College of Wisconsin
Description: SBN/Ygl sequenced by MCW
SBN/Ygl (RGD)
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Platform: Illumina HiSeq 2000
Secondary Analysis: BWA mem 0.7.15, GATK v.3.6-0
Description: Sequences from Atanur et al and Hermsen et al realigned to the Rnor 6.0 assembly and reanalyzed by RGD
SHR/NHsd (RGD)
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Platform: Illumina HiSeq 2000
Secondary Analysis: BWA mem 0.7.15, GATK v.3.6-0
Description: Sequences from Atanur et al and Hermsen et al realigned to the Rnor 6.0 assembly and reanalyzed by RGD
SHRSP/Gcrc (RGD)
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Platform: Illumina HiSeq 2000
Secondary Analysis: BWA mem 0.7.15, GATK v.3.6-0
Description: Sequences from Atanur et al and Hermsen et al realigned to the Rnor 6.0 assembly and reanalyzed by RGD
SR/JrHsd (MCW)
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Sequenced By: Medical College of Wisconsin (Dr. Howard Jacob)
Platform: Illumina HiSeq 2000
Secondary Analysis: BWA v0.7.7 and GATK v3.2-2
Breeder: Harlan Laboratories
Description: Provided by the Medical College of Wisconsin (Dr. Howard Jacob)
SR/JrHsd (RGD)
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Platform: Illumina HiSeq 2000
Secondary Analysis: BWA mem 0.7.15, GATK v.3.6-0
Description: Sequences from Atanur et al and Hermsen et al realigned to the Rnor 6.0 assembly and reanalyzed by RGD
SS/Jr (RGD)
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Platform: Illumina HiSeq 2000
Secondary Analysis: BWA mem 0.7.15, GATK v.3.6-0
Description: Sequences from Atanur et al and Hermsen et al realigned to the Rnor 6.0 assembly and reanalyzed by RGD
SS/JrHsdMcwi (MCW)
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Sequenced By: Medical College of Wisconsin (Dr. Howard Jacob)
Platform: Illumina HiSeq 2000
Secondary Analysis: BWA v0.7.7 and GATK v3.2-2
Breeder: Medical College of Wisconsin
Description: Provided by the Medical College of Wisconsin (Dr. Howard Jacob)
SS/JrHsdMcwi (RGD)
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Platform: Illumina HiSeq 2000
Secondary Analysis: BWA mem 0.7.15, GATK v.3.6-0
Description: Sequences from Atanur et al and Hermsen et al realigned to the Rnor 6.0 assembly and reanalyzed by RGD
WAG/Rij (RGD)
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Platform: Illumina HiSeq 2000
Secondary Analysis: BWA mem 0.7.15, GATK v.3.6-0
Description: Sequences from Atanur et al and Hermsen et al realigned to the Rnor 6.0 assembly and reanalyzed by RGD
WKY/Gcrc (RGD)
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Platform: Illumina HiSeq 2000
Secondary Analysis: BWA mem 0.7.15, GATK v.3.6-0
Description: Sequences from Atanur et al and Hermsen et al realigned to the Rnor 6.0 assembly and reanalyzed by RGD
WKY/N (MCW)
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Sequenced By: Royal Netherland Academy of Arts and Sciences (Dr. Edwin Cuppen)
Max Delbruck Center for Molecular Medicine (Dr. Norbert Huebner)
Platform: SOLiD 4 and 5500
Secondary Analysis: liftOver (Batch Coordinate Conversion)--genome.ucsc.edu
Breeder: National Institutes of Health
Description: Founder strain for the heterogeneous stock (HS) rat population; SNPs from the RGSC 3.4 assembly were "lifted over" from RGSC 3.4 to Rnor 5.0 and from Rnor 5.0 to Rnor 6.0; Provided by Medical College of Wisconsin
WKY/NCrl (RGD)
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Platform: Illumina HiSeq 2000
Secondary Analysis: BWA mem 0.7.15, GATK v.3.6-0
Description: Sequences from Atanur et al and Hermsen et al realigned to the Rnor 6.0 assembly and reanalyzed by RGD
WKY/NHsd (RGD)
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Platform: Illumina HiSeq 2000
Secondary Analysis: BWA mem 0.7.15, GATK v.3.6-0
Description: Sequences from Atanur et al and Hermsen et al realigned to the Rnor 6.0 assembly and reanalyzed by RGD
WN/N (MCW)
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Sequenced By: Royal Netherland Academy of Arts and Sciences (Dr. Edwin Cuppen)
Max Delbruck Center for Molecular Medicine (Dr. Norbert Huebner)
Platform: SOLiD 4 and 5500
Secondary Analysis: liftOver (Batch Coordinate Conversion)--genome.ucsc.edu
Breeder: National Institutes of Health
Description: Founder strain for the heterogeneous stock (HS) rat population; SNPs from the RGSC 3.4 assembly were "lifted over" from RGSC 3.4 to Rnor 5.0 and from Rnor 5.0 to Rnor 6.0; Provided by Medical College of Wisconsin
Damaging Variants


Assembly: Rnor_5.0

Chromosome Start Pos End Pos Reference Nucleotide Variant Nucleotide Variant Type Strain
10 34311673 34311674 C T snv FHL/EurMcwi (MCW), FHH/EurMcwi (MCW)
10 34311791 34311792 C A snv COP/CrCrl (MCW & UW), IS/Kyo (KyushuU), IS-Tlk/Kyo (KyushuU), ACI/EurMcwi (MCW)
10 34312348 34312349 G A snv FHL/EurMcwi (MCW), FHH/EurMcwi (MCW)
10 34312453 34312454 T A snv FHH/EurMcwi (MCW), FHL/EurMcwi (MCW)


Assembly: Rnor_6.0

Chromosome Start Pos End Pos Reference Nucleotide Variant Nucleotide Variant Type Strain
10 34535356 34535357 C T snv FHH/EurMcwi (MCW), FHL/EurMcwi (MCW)
10 34535474 34535475 C A snv ACI/N (MCW), COP/CrCrl (MCW & UW), ACI/EurMcwi (RGD), ACI/EurMcwi (MCW)
10 34536031 34536032 G A snv FHH/EurMcwi (MCW), FHL/EurMcwi (MCW)
10 34536136 34536137 T A snv FHL/EurMcwi (MCW), FHH/EurMcwi (MCW)


Assembly: RGSC_v3.4

Chromosome Start Pos End Pos Reference Nucleotide Variant Nucleotide Variant Type Strain
10 34722474 34722475 C T snv FHH/EurMcwi (MCW), FHL/EurMcwi (MCW), FHH/EurMcwi (MDC)
10 34722592 34722593 C A snv ACI/N (KNAW), ACI/EurMcwi (MCW), COP/CrCrl (MCW & UW)
10 34723149 34723150 G A snv FHH/EurMcwi (MCW), FHH/EurMcwi (MDC), FHL/EurMcwi (MCW)
10 34723254 34723255 T A snv FHL/EurMcwi (MCW), FHH/EurMcwi (MDC), FHH/EurMcwi (MCW)


Additional Information

Database Acc Id Source(s)
AGR Gene RGD:620097 AgrOrtholog
Ensembl Genes ENSRNOG00000031208 Ensembl, ENTREZGENE, UniProtKB/Swiss-Prot
Ensembl Protein ENSRNOP00000044560 ENTREZGENE, UniProtKB/Swiss-Prot
  ENSRNOP00000068827 ENTREZGENE, UniProtKB/Swiss-Prot
Ensembl Transcript ENSRNOT00000052360 ENTREZGENE, UniProtKB/Swiss-Prot
  ENSRNOT00000085832 UniProtKB/Swiss-Prot
Gene3D-CATH 3.90.550.10 UniProtKB/Swiss-Prot
IMAGE_CLONE IMAGE:7100030 IMAGE-MGC_LOAD
InterPro Glyco_trans_13 UniProtKB/Swiss-Prot
  Nucleotide-diphossugar_trans UniProtKB/Swiss-Prot
KEGG Report rno:81519 UniProtKB/Swiss-Prot
MGC_CLONE MGC:91661 IMAGE-MGC_LOAD
NCBI Gene 81519 ENTREZGENE
Pfam GNT-I UniProtKB/Swiss-Prot
PhenoGen Mgat1 PhenoGen
Superfamily-SCOP SSF53448 UniProtKB/Swiss-Prot
UniProt MGAT1_RAT UniProtKB/Swiss-Prot, ENTREZGENE


Nomenclature History
Date Current Symbol Current Name Previous Symbol Previous Name Description Reference Status
2019-09-13 Mgat1  alpha-1,3-mannosyl-glycoprotein 2-beta-N-acetylglucosaminyltransferase  Mgat1  mannosyl (alpha-1,3-)-glycoprotein beta-1,2-N-acetylglucosaminyltransferase  Nomenclature updated to reflect human and mouse nomenclature 1299863 APPROVED
2008-08-29 Mgat1  mannosyl (alpha-1,3-)-glycoprotein beta-1,2-N-acetylglucosaminyltransferase  Mgat1  mannoside acetylglucosaminyltransferase 1  Nomenclature updated to reflect human and mouse nomenclature 1299863 APPROVED
2006-03-30 Mgat1  mannoside acetylglucosaminyltransferase 1    Alpha-1,3-mannosyl-glycoprotein 2-beta-N-acetylglucosaminyltransferase  Name updated 1299863 APPROVED
2005-01-20 Mgat1  Alpha-1,3-mannosyl-glycoprotein 2-beta-N-acetylglucosaminyltransferase    N-acetylglucosaminyltransferase I  Name updated 1299863 APPROVED
2002-08-07 Mgat1  N-acetylglucosaminyltransferase I      Symbol and Name status set to provisional 70820 PROVISIONAL

RGD Curation Notes
Note Type Note Reference
gene_expression expressed in liver 729009