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Gene: Il4 (interleukin 4) Rattus norvegicus
Symbol: Il4
Name: interleukin 4
Description: Predicted to have cytokine activity. Involved in several processes, including positive regulation of leukocyte migration; regulation of defense response; and regulation of reactive oxygen species biosynthetic process. Localizes to extracellular space. Used to study anti-basement membrane glomerulonephritis; autoimmune thyroiditis; and pelvic inflammatory disease. Biomarker of several diseases, including cerebrovascular disease (multiple); interstitial lung disease (multiple); irritant dermatitis; primary biliary cirrhosis; and rhinitis (multiple). Human ortholog(s) of this gene implicated in several diseases, including autoimmune hypersensitivity disease (multiple); hepatitis B; hepatitis C; pancreatic cancer (multiple); and vasculitis (multiple). Orthologous to human IL4 (interleukin 4); PARTICIPATES IN Fc epsilon receptor mediated signaling pathway; interleukin-12 signaling pathway; interleukin-4 signaling pathway; INTERACTS WITH (R)-lipoic acid; 1,2-dichloroethane; 2,4,6-trinitrobenzenesulfonic acid.
Type: protein-coding
Also known as: B-cell growth factor 1; B-cell IGG differentiation factor; B-cell stimulatory factor 1; BSF-1; IL-4; Il4e12; interleukin-4; lymphocyte stimulatory factor 1
Homo sapiens (human) : IL4 (interleukin 4)  HGNC  Alliance
Mus musculus (house mouse) : Il4 (interleukin 4)  MGI  Alliance
Chinchilla lanigera (long-tailed chinchilla) : Il4 (interleukin 4)
Pan paniscus (bonobo/pygmy chimpanzee) : IL4 (interleukin 4)
Canis lupus familiaris (dog) : IL4 (interleukin 4)
Ictidomys tridecemlineatus (thirteen-lined ground squirrel) : Il4 (interleukin 4)
Sus scrofa (pig) : IL4 (interleukin 4)
Chlorocebus sabaeus (African green monkey) : IL4 (interleukin 4)
Heterocephalus glaber (naked mole-rat) : Il4 (interleukin 4)
more info ...
Latest Assembly: Rnor_6.0 - RGSC Genome Assembly v6.0
Rat AssemblyChrPosition (strand)SourceGenome Browsers
Rnor_6.01038,963,979 - 38,969,531 (-)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl1038,963,979 - 38,969,531 (-)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.01038,745,706 - 38,751,258 (-)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.41039,074,582 - 39,080,134 (-)NCBIRGSC3.4rn4RGSC3.4
RGSC_v3.11039,083,152 - 39,088,705 (-)NCBI
Celera1037,115,496 - 37,120,965 (-)NCBICelera
Cytogenetic Map10q22NCBI
JBrowse: View Region in Genome Browser (JBrowse)

Disease Annotations
Gene-Chemical Interaction Annotations
Gene Ontology Annotations
Molecular Pathway Annotations
References - curated
References - uncurated


Candidate Gene Status
Comparative Map Data
Position Markers
QTLs in Region (Rnor_6.0)
miRNA Target Status


RNA-SEQ Expression


Nucleotide Sequences
Protein Sequences

Strain Variation

Strain Sequence Variants (Rnor 6.0)