IL4 (interleukin 4) - Rat Genome Database

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Gene: IL4 (interleukin 4) Homo sapiens
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Symbol: IL4
Name: interleukin 4
RGD ID: 736306
HGNC Page HGNC:6014
Description: Enables cytokine activity. Involved in several processes, including cell surface receptor signaling pathway; negative regulation of cellular response to transforming growth factor beta stimulus; and regulation of gene expression. Acts upstream of or within positive regulation of cell migration and positive regulation of cell population proliferation. Is active in extracellular space. Implicated in several diseases, including asthma (multiple); atopic dermatitis; autoimmune disease (multiple); pancreatic cancer (multiple); and viral hepatitis (multiple). Biomarker of several diseases, including allergic rhinitis; alopecia universalis; anogenital venereal wart; autoimmune disease (multiple); and liver disease (multiple).
Type: protein-coding
RefSeq Status: REVIEWED
Previously known as: B cell growth factor 1; B-cell stimulatory factor 1; B_cell stimulatory factor 1; BCGF-1; BCGF1; binetrakin; BSF-1; BSF1; IL-4; interleukin 4 variant 2; interleukin-4; lymphocyte stimulatory factor 1; MGC79402; pitrakinra
RGD Orthologs
Mouse
Rat
Chinchilla
Bonobo
Dog
Pig
Green Monkey
Naked Mole-Rat
Alliance Orthologs
More Info more info ...
Allele / Splice: See ClinVar data
Latest Assembly: GRCh38 - Human Genome Assembly GRCh38
NCBI Annotation Information: Note: This gene has been reviewed for its involvement in coronavirus biology, and is relevant for disease process.
Position:
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh385132,673,989 - 132,682,678 (+)NCBIGRCh38GRCh38hg38GRCh38
GRCh38.p14 Ensembl5132,673,986 - 132,682,678 (+)EnsemblGRCh38hg38GRCh38
GRCh375132,009,681 - 132,018,370 (+)NCBIGRCh37GRCh37hg19GRCh37
Build 365132,037,272 - 132,046,267 (+)NCBINCBI36Build 36hg18NCBI36
Build 345132,037,271 - 132,046,267NCBI
Celera5128,139,502 - 128,148,524 (+)NCBICelera
Cytogenetic Map5q31.1NCBI
HuRef5127,201,979 - 127,210,672 (+)NCBIHuRef
CHM1_15131,442,973 - 131,451,670 (+)NCBICHM1_1
T2T-CHM13v2.05133,193,788 - 133,202,478 (+)NCBIT2T-CHM13v2.0
JBrowse: View Region in Genome Browser (JBrowse)
Model


Disease Annotations     Click to see Annotation Detail View
abdominal aortic aneurysm  (ISO)
Acute Experimental Pancreatitis  (ISO)
Acute Hepatitis  (ISO)
Acute Lung Injury  (ISO)
acute myocardial infarction  (ISO)
adult T-cell leukemia/lymphoma  (EXP)
allergic contact dermatitis  (EXP)
allergic disease  (EXP)
allergic rhinitis  (EXP,IEP,ISO)
alopecia universalis  (IEP)
Alzheimer's disease  (IAGP)
Anaphylaxis  (IEP,ISO)
anogenital venereal wart  (IEP)
anti-basement membrane glomerulonephritis  (ISO)
aspirin-induced respiratory disease  (IAGP)
asthma  (EXP,IAGP,IEP,ISO)
atopic dermatitis  (EXP,IAGP,IEP,ISS)
autistic disorder  (EXP)
autoimmune disease  (EXP)
autoimmune hepatitis  (EXP,IAGP,IEP,ISO)
autoimmune thrombocytopenic purpura  (IAGP)
autoimmune thyroiditis  (ISO)
Behcet's disease  (IAGP)
biliary tract benign neoplasm  (IMP)
Bovine Tuberculosis  (EXP)
Brain Injuries  (ISO)
bronchiolitis obliterans  (ISO)
cardiomyopathy  (EXP)
carotid stenosis  (ISO)
Chemical and Drug Induced Liver Injury  (EXP)
cholestasis  (ISO)
Chromosome Breakage  (EXP)
Chronic Hepatitis B  (IAGP,IEP)
Chronic Hepatitis C  (IAGP,IEP)
cognitive disorder  (ISO)
colitis  (EXP,ISO)
common cold  (ISO)
contact dermatitis  (ISO)
COVID-19  (IEP)
cutaneous leishmaniasis  (EXP)
cystic echinococcosis  (IEP)
cystitis  (ISO)
dermatitis  (EXP)
dermatomyositis  (IEP)
drug allergy  (EXP)
Drug Eruptions  (EXP)
Edema  (IDA)
Experimental Arthritis  (EXP,IDA,ISO)
Experimental Autoimmune Encephalomyelitis  (ISO)
Experimental Autoimmune Uveoretinitis  (ISO)
Experimental Diabetes Mellitus  (ISO)
Experimental Liver Cirrhosis  (ISO)
familial adenomatous polyposis 1  (IAGP)
Fibrosis  (EXP,ISO)
Gaucher's disease  (ISO)
Granuloma  (ISO)
Graves' disease  (EXP)
Hand Osteoarthritis  (IAGP)
Hemorrhagic Shock  (ISO)
hepatitis B  (IAGP)
hepatitis C  (IAGP,IEP)
Hereditary Neoplastic Syndromes  (IAGP)
herpes zoster  (IEP)
high grade glioma  (ISO)
Human Influenza  (ISO)
hypothyroidism  (ISO)
Immediate Hypersensitivity  (EXP)
irritant dermatitis  (ISO)
Kawasaki disease  (ISO)
Knee Osteoarthritis  (IAGP,ISO)
leishmaniasis  (IEP,ISO)
Lung Reperfusion Injury  (ISO)
malignant mesothelioma  (EXP)
Meningococcal Infections  (IAGP)
metabolic dysfunction-associated steatotic liver disease  (EXP)
middle cerebral artery infarction  (ISO)
multiple sclerosis  (IAGP)
Nematode Infections  (ISO)
nephritis  (ISO)
nephrotic syndrome  (ISO)
Neurodevelopmental Disorders  (IAGP)
Otitis Media with Effusion  (ISO)
pancreatic cancer  (IEP,IMP,ISO)
pancreatic ductal carcinoma  (IMP)
pelvic inflammatory disease  (ISO)
Perennial Allergic Rhinitis  (IEP)
pleural disease  (EXP)
pneumoconiosis  (EXP)
pneumonia  (EXP,HEP)
polymyositis  (IEP)
Premature Birth  (EXP)
primary biliary cholangitis  (ISO)
primary cutaneous T-cell non-Hodgkin lymphoma  (IEP)
psoriasis  (EXP,IEP,ISO)
pulmonary fibrosis  (EXP,ISO)
pulmonary hypertension  (ISO)
pulmonary tuberculosis  (ISO)
respiratory allergy  (EXP,ISO)
Respiratory Sounds  (EXP)
Respiratory Tract Infections  (IEP)
rhinitis  (EXP,ISO)
Rhinosinusitis  (IEP)
Seasonal Allergic Rhinitis  (IEP)
Sepsis  (IEP)
Sjogren's syndrome  (ISS)
Spinal Cord Injuries  (ISO)
Staphylococcal Infections  (IAGP)
Stroke  (IEP)
systemic lupus erythematosus  (EXP)
systemic scleroderma  (IEP)
temporal arteritis  (IAGP)
toxocariasis  (IEP)
trypanosomiasis  (ISO)
type 1 diabetes mellitus  (ISS)
vitiligo  (IEP)
Weight Loss  (EXP)
Xerostomia  (ISO)

Gene-Chemical Interaction Annotations     Click to see Annotation Detail View
(+)-trans-(S)-allethrin  (EXP)
(-)-matairesinol  (ISO)
(20S)-ginsenoside Rh1  (ISO)
(4-oxo-3-\{[5-(trifluoromethyl)-1,3-benzothiazol-2-yl]methyl\}-3,4-dihydrophthalazin-1-yl)acetic acid  (ISO)
(R)-lipoic acid  (ISO)
1,2-dibutyrin  (ISO)
1,2-dichloroethane  (ISO)
1,3,5-trinitrobenzene  (ISO)
1,4-phenylenediamine  (ISO)
1-chloro-2,4,6-trinitrobenzene  (EXP,ISO)
1-chloro-2,4-dinitrobenzene  (ISO)
1-fluoro-2,4-dinitrobenzene  (ISO)
1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine  (ISO)
13,14-dihydro-15-ketoprostaglandin D2  (ISO)
15-acetyldeoxynivalenol  (ISO)
15-deoxy-Delta(12,14)-prostaglandin J2  (EXP)
17alpha-ethynylestradiol  (ISO)
17beta-estradiol  (EXP,ISO)
17beta-hydroxy-5alpha-androstan-3-one  (ISO)
2,2',4,4'-Tetrabromodiphenyl ether  (ISO)
2,2,3,3,4,4,5,5,6,6,7,7,8,8,9,9-hexadecafluorononanoic acid  (ISO)
2,3,7,8-tetrachlorodibenzodioxine  (EXP,ISO)
2,4,6-trinitrobenzenesulfonic acid  (EXP,ISO)
2,4-D  (ISO)
2,4-dibromophenyl 2,4,5-tribromophenyl ether  (ISO)
2,6-di-tert-butyl-4-methylphenol  (ISO)
2-amino-2-deoxy-D-glucopyranose  (EXP,ISO)
2-butan-2-yl-4-[4-[4-[4-[[2-(2,4-dichlorophenyl)-2-(1,2,4-triazol-1-ylmethyl)-1,3-dioxolan-4-yl]methoxy]phenyl]-1-piperazinyl]phenyl]-1,2,4-triazol-3-one  (EXP)
2-tert-butylhydroquinone  (EXP,ISO)
3',5'-cyclic AMP  (EXP)
3,3',5,5'-tetrabromobisphenol A  (ISO)
3-acetyldeoxynivalenol  (ISO)
3-chloropropane-1,2-diol  (ISO)
3-isobutyl-1-methyl-7H-xanthine  (EXP)
3H-1,2-dithiole-3-thione  (ISO)
4'-hydroxydiclofenac  (EXP)
4,4'-diaminodiphenylmethane  (EXP)
4,4'-sulfonyldiphenol  (EXP,ISO)
4-(ethoxymethylene)-2-phenyloxazol-5-one  (ISO)
4-ethylphenol  (ISO)
4-nitro-m-cresol  (ISO)
4-nonylphenol  (EXP)
4-tolyl isocyanate  (ISO)
5-azacytidine  (EXP)
6-anilino-5,8-quinolinedione  (ISO)
6-Methoxyflavone  (ISO)
6alpha-methylprednisolone  (EXP,ISO)
8-Br-cAMP  (EXP)
8-bromo-3',5'-cyclic GMP  (ISO)
9-cis-retinoic acid  (EXP,ISO)
abacavir  (EXP)
acetaldehyde  (EXP)
acetone  (EXP)
acetylsalicylic acid  (EXP)
acrylic acid  (ISO)
albuterol  (EXP)
alclometasone dipropionate  (EXP)
aldehydo-D-glucosamine  (EXP,ISO)
all-trans-retinoic acid  (EXP,ISO)
all-trans-retinol  (ISO)
allicin  (ISO)
alpha-galactosylceramide  (ISO)
alpha-hexylcinnamaldehyde  (EXP,ISO)
alpha-linolenic acid  (EXP)
aluminium atom  (ISO)
aluminium hydroxide  (EXP,ISO)
aluminium sulfate (anhydrous)  (ISO)
aluminium(0)  (ISO)
amiodarone  (EXP,ISO)
ammonium chloride  (ISO)
amorolfine  (EXP)
anthra[1,9-cd]pyrazol-6(2H)-one  (ISO)
antigen  (ISO)
apigenin  (EXP,ISO)
arachidonic acid  (EXP)
arsane  (EXP,ISO)
arsenic atom  (EXP,ISO)
arsenous acid  (EXP,ISO)
asbestos  (EXP,ISO)
asperentin  (ISO)
atrazine  (ISO)
azathioprine  (EXP)
Azoxymethane  (ISO)
BAPTA  (EXP)
bazedoxifene  (EXP)
beclomethasone  (EXP,ISO)
benzalkonium chloride  (ISO)
benzene  (EXP)
benzo[a]pyrene  (EXP,ISO)
benzofurans  (ISO)
berberine  (ISO)
beta-D-glucosamine  (EXP,ISO)
beta-endorphin  (EXP)
betamethasone valerate  (EXP)
bexarotene  (EXP,ISO)
bifenthrin  (ISO)
biochanin A  (ISO)
bis(2-chloroethyl) sulfide  (ISO)
bis(2-ethylhexyl) phthalate  (EXP,ISO)
bisphenol A  (EXP,ISO)
bisphenol F  (EXP,ISO)
bleomycin A2  (EXP,ISO)
boric acid  (ISO)
boron atom  (ISO)
Brevetoxin B  (EXP)
bucladesine  (EXP)
budesonide  (ISO)
buprenorphine  (EXP)
butane-2,3-dione  (ISO)
butenafine  (EXP)
Butylbenzyl phthalate  (ISO)
cadmium atom  (EXP,ISO)
cadmium dichloride  (EXP)
Calcimycin  (EXP,ISO)
calciol  (ISO)
calcipotriol  (ISO)
calcitriol  (EXP,ISO)
calcium atom  (ISO)
calcium(0)  (ISO)
cannabidiol  (ISO)
capsaicin  (ISO)
capsazepine  (ISO)
carbachol  (ISO)
carbamazepine  (ISO)
carbon monoxide  (EXP,ISO)
carbon nanotube  (EXP,ISO)
carveol  (ISO)
caryophyllene oxide  (ISO)
ceric oxide  (ISO)
cerium trichloride  (ISO)
cetirizine  (ISO)
chlorambucil  (EXP)
chloroform  (ISO)
chloroquine  (ISO)
chlorphenamine  (ISO)
chlorpyrifos  (EXP)
choline  (ISO)
chromium atom  (ISO)
chromium(6+)  (EXP)
chrysin  (EXP,ISO)
cilostazol  (ISO)
ciprofloxacin  (EXP)
cis-caffeic acid  (ISO)
cisplatin  (EXP,ISO)
cladribine  (EXP)
clarithromycin  (EXP)
clopidogrel  (ISO)
cobalt atom  (EXP)
cobalt dichloride  (ISO)
cocaine  (EXP)
colforsin daropate hydrochloride  (EXP)
copper atom  (ISO)
copper(0)  (ISO)
copper(II) sulfate  (EXP)
cordycepin  (EXP,ISO)
corn oil  (ISO)
cortisol  (ISO)
crocidolite asbestos  (ISO)
cupressuflavone  (ISO)
curcumin  (ISO)
cycloastragenol  (ISO)
cyclopentanes  (EXP)
cyclophosphamide  (ISO)
cyclosporin A  (EXP,ISO)
cyfluthrin  (EXP)
cyhalothrin  (ISO)
D-penicillamine  (ISO)
daidzein  (ISO)
DDE  (EXP,ISO)
DDT  (EXP)
decabromodiphenyl ether  (ISO)
deguelin  (ISO)
deoxynivalenol  (EXP,ISO)
desferrioxamine B  (ISO)
dexamethasone  (EXP,ISO)
dextran sulfate  (ISO)
Di-n-octyl phthalate  (ISO)
Diallyl sulfide  (ISO)
diarsenic trioxide  (EXP,ISO)
diazinon  (EXP,ISO)
dibenzothiazol-2-yl disulfide  (ISO)
dibutyl phthalate  (ISO)
diclofenac  (EXP)
dicloxacillin  (ISO)
dicyclohexylmethane-4,4'-diisocyanate  (ISO)
Didecyldimethylammonium  (ISO)
diethyl maleate  (EXP)
diethyl phthalate  (ISO)
diethylamine  (ISO)
diflorasone  (ISO)
Diisodecyl phthalate  (ISO)
diisononyl phthalate  (ISO)
diisopropyl fluorophosphate  (ISO)
Dimaprit  (ISO)
Dimethyl phthalate  (ISO)
dioscin  (ISO)
dioxygen  (EXP,ISO)
diphenylmethane-4,4'-diisocyanate  (ISO)
dipotassium bis[mu-tartrato(4-)]diantimonate(2-) trihydrate  (EXP)
diuron  (EXP)
donepezil hydrochloride  (ISO)
doxorubicin  (EXP,ISO)
dydrogesterone  (EXP,ISO)
edaravone  (ISO)
elemental boron  (ISO)
elemental selenium  (ISO)
emamectin benzoate  (EXP)
emodin  (ISO)
epinastine  (EXP,ISO)
equol  (ISO)
Erionite  (ISO)
estriol  (ISO)
ethanol  (ISO)
etoposide  (EXP)
famotidine  (ISO)
fentanyl  (EXP)
ferric oxide  (ISO)
fingolimod hydrochloride  (ISO)
fisetin  (EXP)
flavonoids  (EXP)
fluoranthene  (EXP)
fluorescein 5-isothiocyanate  (ISO)
flutamide  (ISO)
fluticasone  (EXP)
folic acid  (ISO)
fomepizole  (ISO)
formaldehyde  (ISO)
formononetin  (ISO)
formoterol fumarate  (EXP,ISO)
fragrance  (EXP)
fulvestrant  (ISO)
furfuryl alcohol  (ISO)
gadodiamide hydrate  (EXP)
gadolinium trichloride  (EXP)
Ganoderic acid C2  (ISO)
Gastrodin  (ISO)
gemcitabine  (EXP)
genistein  (ISO)
ginsenoside C-K  (ISO)
glutathione  (EXP,ISO)
Glutathione ethyl ester  (ISO)
gold atom  (EXP)
gold(0)  (EXP)
gossypin  (ISO)
graphite  (ISO)
GSK2193874  (ISO)
harmaline  (ISO)
helenalin  (EXP)
heroin  (EXP)
hesperidin  (ISO)
hexachlorobenzene  (ISO)
hexamethylene diisocyanate  (ISO)
hispidulin  (EXP)
histamine  (ISO)
Honokiol  (EXP)
hydrogen peroxide  (ISO)
hydroquinone  (ISO)
hydroxysafflor yellow A  (ISO)
hydroxyzine  (ISO)
ibuprofen  (ISO)
IC-87114  (ISO)
idelalisib  (ISO)
imidacloprid  (ISO)
imiquimod  (EXP)
immunological adjuvant  (EXP)
Indeno[1,2,3-cd]pyrene  (ISO)
indirubin  (EXP)
indometacin  (EXP,ISO)
ionomycin  (EXP,ISO)
iron(2+) sulfate (anhydrous)  (EXP)
isophorone diisocyanate  (ISO)
isoprenaline  (EXP,ISO)
isosilybin A  (ISO)
isotretinoin  (ISO)
itraconazole  (EXP)
kaempferol  (EXP)
ketoconazole  (EXP)
ketorolac  (EXP)
L-arginine  (ISO)
L-ascorbic acid  (ISO)
lactacystin  (ISO)
lead diacetate  (ISO)
lead(0)  (ISO)
lead(II) chloride  (ISO)
leflunomide  (EXP,ISO)
leukotriene B4  (EXP)
levamisole  (ISO)
lidocaine  (ISO)
linoleic acid  (EXP)
lipoic acid  (ISO)
lipopolysaccharide  (EXP,ISO)
lipoteichoic acid  (ISO)
lipoxin A4  (ISO)
lithium atom  (ISO)
lithium hydride  (ISO)
loperamide  (EXP)
losartan  (ISO)
Luliconazole  (EXP)
luteolin  (EXP,ISO)
Luteolin 7-methyl ether  (ISO)
LY294002  (ISO)
malathion  (ISO)
manganese atom  (ISO)
manganese(0)  (ISO)
manganese(II) chloride  (ISO)
melatonin  (ISO)
mercury atom  (ISO)
mercury dichloride  (EXP,ISO)
mercury(0)  (ISO)
mesalamine  (ISO)
methadone  (EXP)
methanol  (ISO)
methimazole  (ISO)
methotrexate  (EXP)
methoxychlor  (ISO)
methyl isocyanate  (EXP)
methyl salicylate  (ISO)
miconazole  (EXP)
microcystin-LR  (ISO)
mifepristone  (EXP,ISO)
mitogen  (ISO)
MK 571  (ISO)
Monobutylphthalate  (EXP)
monodansylcadaverine  (ISO)
montelukast  (ISO)
morphine  (EXP,ISO)
Morroniside  (ISO)
moxifloxacin  (EXP)
mycophenolic acid  (ISO)
N,N,N',N'-tetrakis(2-pyridylmethyl)ethylenediamine  (EXP)
N,N-diethyl-m-toluamide  (ISO)
N-[2-(4-bromocinnamylamino)ethyl]isoquinoline-5-sulfonamide  (EXP)
N-acetyl-beta-D-glucosamine  (ISO)
N-acetyl-D-glucosamine  (ISO)
N-acetyl-L-cysteine  (EXP,ISO)
N-methyl-4-phenylpyridinium  (ISO)
N-methyl-N-nitrosourea  (ISO)
N-nitrosodiethylamine  (ISO)
N1'-[2-[[5-[(dimethylamino)methyl]-2-furanyl]methylthio]ethyl]-N1-methyl-2-nitroethene-1,1-diamine  (ISO)
naphthalene  (EXP)
naproxen  (ISO)
naringin  (ISO)
neocuproine  (ISO)
nicardipine  (ISO)
nickel atom  (EXP)
nickel dichloride  (EXP)
nickel sulfate  (EXP)
nitrendipine  (ISO)
nitric oxide  (EXP,ISO)
nitrites  (ISO)
nitrogen dioxide  (ISO)
nitroprusside  (EXP,ISO)
Nivalenol  (ISO)
nonanoic acid  (ISO)
Nonylphenol  (ISO)
NS-398  (ISO)
obeticholic acid  (ISO)
ochratoxin A  (ISO)
okadaic acid  (ISO)
Olopatadine hydrochloride  (ISO)
ozone  (EXP,ISO)
paracetamol  (EXP,ISO)
paraquat  (EXP,ISO)
parathion  (ISO)
patulin  (EXP)
PCB138  (EXP)
pentachlorophenol  (ISO)
pentamidine  (ISO)
Pentoxifylline  (ISO)
perfluorononanoic acid  (ISO)
perfluorooctane-1-sulfonic acid  (EXP,ISO)
perfluorooctanoic acid  (EXP)
permethrin  (ISO)
phorbol 13-acetate 12-myristate  (EXP,ISO)
phosgene  (ISO)
phthalaldehyde  (ISO)
phthalic anhydride  (EXP,ISO)
pioglitazone  (ISO)
piperonyl butoxide  (EXP,ISO)
pirinixic acid  (ISO)
poly(I:C)  (EXP,ISO)
polyphosphates  (EXP)
prednisolone  (EXP,ISO)
prednisone  (EXP)
progesterone  (EXP,ISO)
prostaglandin D2  (EXP)
prostaglandin E2  (EXP,ISO)
prostaglandin F2alpha  (EXP)
pyrene  (EXP,ISO)
Pyridostigmine bromide  (ISO)
pyruvic acid  (ISO)
quercetin  (EXP,ISO)
raloxifene  (EXP,ISO)
ranitidine  (ISO)
reactive oxygen species  (EXP)
resveratrol  (EXP,ISO)
retinyl acetate  (ISO)
ribavirin  (EXP)
ricinoleic acid  (EXP)
Ro 41-5253  (EXP)
rolipram  (ISO)
rotenone  (ISO)
S-butyl-DL-homocysteine (S,R)-sulfoximine  (ISO)
salicylic acid  (EXP)
Sanggenon C  (ISO)
SB 203580  (EXP,ISO)
SB 290157  (ISO)
selenium atom  (ISO)
selenomethionine  (ISO)
serotonin  (ISO)
serpentine asbestos  (ISO)
sildenafil citrate  (ISO)
silicon dioxide  (ISO)
Silidianin  (ISO)
silver(1+) nitrate  (ISO)
simvastatin  (EXP,ISO)
sirolimus  (ISO)
sodium arsenite  (EXP,ISO)
sodium aurothiomalate  (ISO)
sodium benzoate  (EXP)
sodium dichromate  (EXP,ISO)
sodium dodecyl sulfate  (ISO)
sodium fluoride  (ISO)
sodium hexachloroplatinate  (ISO)
Sodium salicylate  (EXP)
sodium stibogluconate  (EXP,ISO)
solasodine  (ISO)
spathulenol  (ISO)
SR 144528  (EXP)
staurosporine  (ISO)
streptozocin  (ISO)
styrene  (ISO)
Sucralfate  (ISO)
sulfasalazine  (ISO)
sulforaphane  (ISO)
sulfur dioxide  (ISO)
sumatriptan  (ISO)
sunitinib  (ISO)
Sunset Yellow FCF  (ISO)
synephrine  (EXP,ISO)
syringin  (ISO)
T-2 toxin  (ISO)
tacrolimus hydrate  (EXP,ISO)
tamibarotene  (ISO)
tamoxifen  (EXP,ISO)
terbinafine  (EXP)
Terfenadine  (EXP)
tetrachloroethene  (ISO)
tetrachloromethane  (ISO)
tetracyclines  (ISO)
thalidomide  (ISO)
thapsigargin  (ISO)
theophylline  (EXP,ISO)
thioacetamide  (ISO)
thiram  (ISO)
thromboxane B2  (EXP)
thymoquinone  (ISO)
titanium dioxide  (EXP,ISO)
TMC-120A  (ISO)
tofacitinib  (EXP)
tolnaftate  (EXP)
toluene  (ISO)
toluene 2,4-diisocyanate  (EXP,ISO)
trans-caffeic acid  (ISO)
trans-piceid  (ISO)
tremolite asbestos  (ISO)
tributylstannane  (ISO)
Tributyltin oxide  (ISO)
tributyrin  (ISO)
tricaproin  (ISO)
trichloroethene  (EXP,ISO)
triclosan  (ISO)
trimellitic anhydride  (EXP,ISO)
Triptolide  (ISO)
uranium atom  (ISO)
urethane  (ISO)
valproic acid  (EXP,ISO)
vanadium atom  (EXP,ISO)
vanadium(0)  (EXP,ISO)
verrucarin A  (ISO)
vitamin D  (ISO)
vitamin E  (ISO)
WIN 55212-2  (ISO)
wortmannin  (ISO)
zearalenone  (EXP)
zidovudine  (EXP)
zileuton  (ISO)
zinc atom  (EXP,ISO)
zinc oxide  (ISO)
zinc(0)  (EXP,ISO)
ziram  (ISO)

Gene Ontology Annotations     Click to see Annotation Detail View

Biological Process
activated T cell proliferation  (ISO)
B cell activation  (IEA,ISO)
B cell costimulation  (ISO)
B cell differentiation  (TAS)
B cell proliferation  (ISO)
cell surface receptor signaling pathway via JAK-STAT  (IGI)
cellular response to mercury ion  (ISO)
cholesterol metabolic process  (ISS)
defense response to protozoan  (ISO)
dendritic cell differentiation  (IDA)
extrinsic apoptotic signaling pathway  (ISO)
extrinsic apoptotic signaling pathway in absence of ligand  (ISO)
female pregnancy  (ISO)
immune response  (IEA,TAS)
innate immune response in mucosa  (ISO)
interleukin-4-mediated signaling pathway  (IBA,IDA)
isotype switching to IgE isotypes  (ISO)
isotype switching to IgG isotypes  (ISO)
leukocyte activation  (IEA)
macrophage activation  (IGI)
MHC class II biosynthetic process  (ISO)
microglial cell activation  (ISO)
myeloid dendritic cell differentiation  (IDA)
negative regulation of acute inflammatory response  (ISO)
negative regulation of apoptotic process  (ISS)
negative regulation of cellular response to transforming growth factor beta stimulus  (IDA)
negative regulation of chronic inflammatory response  (ISO)
negative regulation of complement-dependent cytotoxicity  (IMP)
negative regulation of DNA-templated transcription  (IDA)
negative regulation of endothelial cell apoptotic process  (IMP)
negative regulation of epithelial cell migration  (IDA)
negative regulation of extrinsic apoptotic signaling pathway  (ISO)
negative regulation of inflammatory response  (IBA,IGI)
negative regulation of macrophage activation  (ISO)
negative regulation of neuroinflammatory response  (IC)
negative regulation of nitric oxide biosynthetic process  (ISO)
negative regulation of osteoclast differentiation  (ISO,ISS)
negative regulation of T cell activation  (ISO)
negative regulation of T-helper 17 cell differentiation  (ISO)
negative regulation of transcription by RNA polymerase II  (IDA)
negative regulation of tumor necrosis factor production  (ISS)
negative regulation of white fat cell proliferation  (ISO)
neuroinflammatory response  (ISS)
peptidyl-tyrosine phosphorylation  (ISO)
positive regulation of activated T cell proliferation  (ISO)
positive regulation of amyloid-beta clearance  (ISS)
positive regulation of ATP biosynthetic process  (ISS)
positive regulation of B cell activation  (ISO)
positive regulation of B cell chemotaxis  (ISO)
positive regulation of B cell proliferation  (ISO,ISS)
positive regulation of cell migration  (IEA,IGI)
positive regulation of cell population proliferation  (IGI,ISO)
positive regulation of cellular respiration  (ISS)
positive regulation of chemokine production  (ISO)
positive regulation of cold-induced thermogenesis  (ISS)
positive regulation of defense response to virus by host  (ISO)
positive regulation of DNA-binding transcription factor activity  (ISO)
positive regulation of DNA-templated transcription  (IBA,IDA,ISO)
positive regulation of eosinophil chemotaxis  (ISO)
positive regulation of establishment of endothelial barrier  (ISO)
positive regulation of gene expression  (IEA,ISS)
positive regulation of immunoglobulin production  (ISO)
positive regulation of interleukin-10 production  (IGI,ISO)
positive regulation of interleukin-13 production  (IDA)
positive regulation of isotype switching to IgE isotypes  (ISO,ISS)
positive regulation of isotype switching to IgG isotypes  (ISO,ISS)
positive regulation of macroautophagy  (ISS)
positive regulation of mast cell degranulation  (ISO)
positive regulation of MHC class II biosynthetic process  (ISO,ISS)
positive regulation of mononuclear cell migration  (ISO)
positive regulation of myoblast fusion  (ISO)
positive regulation of peptidyl-tyrosine phosphorylation  (ISO)
positive regulation of protein phosphorylation  (ISO)
positive regulation of reactive oxygen species biosynthetic process  (ISO)
positive regulation of receptor signaling pathway via JAK-STAT  (ISO)
positive regulation of receptor-mediated endocytosis  (ISS)
positive regulation of T cell differentiation  (IDA)
positive regulation of T cell proliferation  (ISO,ISS)
positive regulation of T-helper 2 cell cytokine production  (IDA)
positive regulation of transcription by RNA polymerase II  (IGI,ISO,ISS)
positive regulation of tyrosine phosphorylation of STAT protein  (ISO)
regulation of immune response  (IBA,ISO,ISS)
regulation of isotype switching  (TAS)
regulation of multicellular organismal process  (IEA)
regulation of primary metabolic process  (IEA)
regulation of protein export from nucleus  (ISO)
regulation of proton transport  (ISO)
response to cytokine  (ISO)
response to ethanol  (ISO)
response to genistein  (ISO)
response to nematode  (ISO)
response to nutrient  (ISO)
response to selenium ion  (ISO)
response to xenobiotic stimulus  (ISO)
retina development in camera-type eye  (ISO)
signal transduction  (IEA)
T cell activation  (IGI)
T cell proliferation  (ISO)
T-helper 1 cell lineage commitment  (ISO)
T-helper 2 cell differentiation  (ISO)
transcription by RNA polymerase II  (ISO)
type 2 immune response  (TAS)
tyrosine phosphorylation of STAT protein  (ISO)

Cellular Component

Molecular Function

Phenotype Annotations     Click to see Annotation Detail View
References

References - curated
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87. KEGG Annotation Import Pipeline Pipeline to import KEGG annotations from KEGG into RGD
88. PID Annotation Import Pipeline Pipeline to import Pathway Interaction Database annotations from NCI into RGD
89. SMPDB Annotation Import Pipeline Pipeline to import SMPDB annotations from SMPDB into RGD
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PMID:22406175   PMID:22441356   PMID:22484241   PMID:22484276   PMID:22512783   PMID:22521249   PMID:22528336   PMID:22538865   PMID:22574929   PMID:22583827   PMID:22615205   PMID:22652416  
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PMID:22997428   PMID:23070918   PMID:23087426   PMID:23107766   PMID:23110190   PMID:23124025   PMID:23128233   PMID:23185315   PMID:23222300   PMID:23234779   PMID:23245479   PMID:23259293  
PMID:23276701   PMID:23306429   PMID:23333304   PMID:23333893   PMID:23334651   PMID:23351078   PMID:23376457   PMID:23394902   PMID:23398789   PMID:23454622   PMID:23511027   PMID:23527200  
PMID:23527710   PMID:23559861   PMID:23572437   PMID:23576103   PMID:23597562   PMID:23644020   PMID:23651591   PMID:23654077   PMID:23668806   PMID:23677722   PMID:23685257   PMID:23694808  
PMID:23742784   PMID:23748736   PMID:23756167   PMID:23756192   PMID:23766027   PMID:23768103   PMID:23771787   PMID:23774696   PMID:23797532   PMID:23831512   PMID:23844087   PMID:23883285  
PMID:23913957   PMID:23923066   PMID:23924473   PMID:23935100   PMID:23936398   PMID:23958647   PMID:23964553   PMID:23983153   PMID:23984295   PMID:24007654   PMID:24049167   PMID:24072495  
PMID:24075353   PMID:24078930   PMID:24089996   PMID:24107646   PMID:24119107   PMID:24161121   PMID:24164868   PMID:24167373   PMID:24169152   PMID:24218339   PMID:24272083   PMID:24280725  
PMID:24313289   PMID:24318972   PMID:24447082   PMID:24447084   PMID:24460857   PMID:24463275   PMID:24463336   PMID:24464250   PMID:24491812   PMID:24510479   PMID:24510574   PMID:24518693  
PMID:24521636   PMID:24628947   PMID:24634237   PMID:24666229   PMID:24668571   PMID:24679691   PMID:24680475   PMID:24707478   PMID:24732061   PMID:24738292   PMID:24742632   PMID:24778440  
PMID:24808368   PMID:24815430   PMID:24819208   PMID:24828787   PMID:24834774   PMID:24850227   PMID:24872120   PMID:24877103   PMID:24906148   PMID:24920818   PMID:24933945   PMID:24939291  
PMID:24943510   PMID:24949794   PMID:24960198   PMID:24991184   PMID:25017270   PMID:25029213   PMID:25060515   PMID:25170298   PMID:25189918   PMID:25239315   PMID:25286078   PMID:25295591  
PMID:25303100   PMID:25308608   PMID:25310970   PMID:25320043   PMID:25330798   PMID:25343318   PMID:25413124   PMID:25418473   PMID:25420534   PMID:25450271   PMID:25454624   PMID:25530681  
PMID:25537796   PMID:25585038   PMID:25646481   PMID:25666199   PMID:25667413   PMID:25674935   PMID:25682112   PMID:25733581   PMID:25747600   PMID:25814340   PMID:25819429   PMID:25826984  
PMID:25853541   PMID:25922277   PMID:25935236   PMID:25942601   PMID:25952120   PMID:25973044   PMID:25985710   PMID:26044597   PMID:26046681   PMID:26070934   PMID:26072972   PMID:26073683  
PMID:26088754   PMID:26093164   PMID:26111149   PMID:26111352   PMID:26138543   PMID:26212175   PMID:26228820   PMID:26231284   PMID:26265379   PMID:26276392   PMID:26288354   PMID:26289664  
PMID:26334904   PMID:26383107   PMID:26405199   PMID:26426602   PMID:26436920   PMID:26440137   PMID:26504066   PMID:26506984   PMID:26507707   PMID:26515179   PMID:26517657   PMID:26537673  
PMID:26562652   PMID:26613553   PMID:26627546   PMID:26646252   PMID:26674732   PMID:26751822   PMID:26755820   PMID:26758199   PMID:26781462   PMID:26829670   PMID:26831416   PMID:26861613  
PMID:26879815   PMID:26927386   PMID:26951255   PMID:26993600   PMID:27000232   PMID:27003899   PMID:27018548   PMID:27072069   PMID:27080531   PMID:27081760   PMID:27100882   PMID:27111145  
PMID:27118451   PMID:27122451   PMID:27165851   PMID:27169944   PMID:27195298   PMID:27212784   PMID:27226435   PMID:27234743   PMID:27235588   PMID:27245778   PMID:27280403   PMID:27323126  
PMID:27363280   PMID:27400089   PMID:27485297   PMID:27488002   PMID:27495027   PMID:27503909   PMID:27507812   PMID:27525870   PMID:27554818   PMID:27556516   PMID:27650274   PMID:27669374  
PMID:27677314   PMID:27742835   PMID:27813599   PMID:27819719   PMID:27888289   PMID:27895317   PMID:27897439   PMID:27996163   PMID:28027921   PMID:28035353   PMID:28036156   PMID:28053321  
PMID:28057814   PMID:28064311   PMID:28064550   PMID:28067328   PMID:28114408   PMID:28142034   PMID:28142109   PMID:28169853   PMID:28189545   PMID:28202459   PMID:28293435   PMID:28350325  
PMID:28365704   PMID:28373981   PMID:28386156   PMID:28387421   PMID:28387873   PMID:28392616   PMID:28400477   PMID:28421819   PMID:28474631   PMID:28476239   PMID:28490634   PMID:28587956  
PMID:28588744   PMID:28617357   PMID:28617966   PMID:28631559   PMID:28652434   PMID:28656227   PMID:28665449   PMID:28694325   PMID:28750137   PMID:28791349   PMID:28838891   PMID:28859277  
PMID:28872970   PMID:28935853   PMID:28950434   PMID:28975976   PMID:29103189   PMID:29135055   PMID:29182400   PMID:29185028   PMID:29236307   PMID:29244911   PMID:29262348   PMID:29297752  
PMID:29298992   PMID:29372577   PMID:29396050   PMID:29514038   PMID:29638207   PMID:29763840   PMID:29861381   PMID:29871928   PMID:29922282   PMID:29953494   PMID:29985726   PMID:30010060  
PMID:30014360   PMID:30022164   PMID:30082430   PMID:30091263   PMID:30104382   PMID:30182172   PMID:30194905   PMID:30227113   PMID:30239037   PMID:30318704   PMID:30345774   PMID:30369370  
PMID:30391589   PMID:30478302   PMID:30480406   PMID:30614113   PMID:30614212   PMID:30634164   PMID:30666720   PMID:30697966   PMID:30729744   PMID:30826860   PMID:30828987   PMID:30849228  
PMID:30891766   PMID:31001272   PMID:31055548   PMID:31097521   PMID:31101790   PMID:31113929   PMID:31217742   PMID:31225812   PMID:31264107   PMID:31400638   PMID:31422745   PMID:31432141  
PMID:31443688   PMID:31540745   PMID:31650822   PMID:31693463   PMID:31798581   PMID:31830807   PMID:31856612   PMID:31871935   PMID:31876620   PMID:31900992   PMID:32032932   PMID:32077194  
PMID:32100006   PMID:32100374   PMID:32112794   PMID:32130032   PMID:32141366   PMID:32295284   PMID:32354899   PMID:32564738   PMID:32603483   PMID:32648256   PMID:32744314   PMID:32781035  
PMID:32810712   PMID:32902809   PMID:32926412   PMID:33038352   PMID:33040814   PMID:33080435   PMID:33087044   PMID:33099387   PMID:33128686   PMID:33154744   PMID:33228581   PMID:33400271  
PMID:33406021   PMID:33413198   PMID:33484701   PMID:33597460   PMID:33804263   PMID:33834211   PMID:33861987   PMID:33895482   PMID:34129931   PMID:34135061   PMID:34182471   PMID:34220814  
PMID:34432782   PMID:34521750   PMID:34607526   PMID:34628505   PMID:34780078   PMID:34799224   PMID:34831232   PMID:34942310   PMID:34973261   PMID:35130415   PMID:35208588   PMID:35216228  
PMID:35254767   PMID:35262550   PMID:35272075   PMID:35292359   PMID:35398375   PMID:35404688   PMID:35456412   PMID:35525950   PMID:35533229   PMID:35778823   PMID:35806269   PMID:35860261  
PMID:35911775   PMID:36168695   PMID:36258103   PMID:36370912   PMID:36519914   PMID:36600245   PMID:36623776   PMID:36657567   PMID:36670145   PMID:36737597   PMID:36738539   PMID:36809715  
PMID:36810600   PMID:36883528   PMID:36905404   PMID:37058046   PMID:37276051   PMID:37364407   PMID:37406292   PMID:37702739   PMID:37803493   PMID:37908348   PMID:37918358   PMID:37921501  
PMID:37949903   PMID:37982769   PMID:38057662   PMID:38069015   PMID:38135009   PMID:38146141   PMID:38147125   PMID:38155071   PMID:38206766   PMID:38238514   PMID:38497343   PMID:38649353  
PMID:38690818   PMID:38725177   PMID:38959653   PMID:39080124   PMID:39242402   PMID:39405377  


Genomics

Comparative Map Data
IL4
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh385132,673,989 - 132,682,678 (+)NCBIGRCh38GRCh38hg38GRCh38
GRCh38.p14 Ensembl5132,673,986 - 132,682,678 (+)EnsemblGRCh38hg38GRCh38
GRCh375132,009,681 - 132,018,370 (+)NCBIGRCh37GRCh37hg19GRCh37
Build 365132,037,272 - 132,046,267 (+)NCBINCBI36Build 36hg18NCBI36
Build 345132,037,271 - 132,046,267NCBI
Celera5128,139,502 - 128,148,524 (+)NCBICelera
Cytogenetic Map5q31.1NCBI
HuRef5127,201,979 - 127,210,672 (+)NCBIHuRef
CHM1_15131,442,973 - 131,451,670 (+)NCBICHM1_1
T2T-CHM13v2.05133,193,788 - 133,202,478 (+)NCBIT2T-CHM13v2.0
Il4
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm391153,503,287 - 53,509,492 (-)NCBIGRCm39GRCm39mm39
GRCm39 Ensembl1153,493,809 - 53,509,496 (-)EnsemblGRCm39 Ensembl
GRCm381153,612,460 - 53,618,665 (-)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl1153,602,982 - 53,618,669 (-)EnsemblGRCm38mm10GRCm38
MGSCv371153,425,962 - 53,432,167 (-)NCBIGRCm37MGSCv37mm9NCBIm37
MGSCv361153,455,891 - 53,462,088 (-)NCBIMGSCv36mm8
Celera1158,191,990 - 58,198,195 (-)NCBICelera
Cytogenetic Map11B1.3NCBI
cM Map1131.97NCBI
Il4
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr81038,272,003 - 38,277,549 (-)NCBIGRCr8
GRCr8 Ensembl1038,272,003 - 38,277,549 (-)EnsemblGRCr8 Ensembl
mRatBN7.21037,771,203 - 37,776,750 (-)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl1037,771,203 - 37,776,750 (-)EnsemblmRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx1042,463,191 - 42,468,731 (-)NCBIRnor_SHRUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.01041,953,256 - 41,958,796 (-)NCBIRnor_SHRSPUTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.01037,456,988 - 37,462,524 (-)NCBIRnor_WKYUTH_Rnor_WKY_Bbb_1.0
Rnor_6.01038,963,979 - 38,969,531 (-)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl1038,963,979 - 38,969,531 (-)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.01038,745,706 - 38,751,258 (-)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.41039,074,582 - 39,080,134 (-)NCBIRGSC3.4RGSC_v3.4rn4RGSC3.4
Celera1037,115,496 - 37,120,965 (-)NCBICelera
RGSC_v3.11039,083,152 - 39,088,705 (-)NCBI
Cytogenetic Map10q22NCBI
Il4
(Chinchilla lanigera - long-tailed chinchilla)
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0NW_0049554084,058,052 - 4,065,999 (+)NCBIChiLan1.0ChiLan1.0
IL4
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
NHGRI_mPanPan1-v24127,986,571 - 127,995,112 (+)NCBINHGRI_mPanPan1-v2
NHGRI_mPanPan15126,126,136 - 126,134,677 (+)NCBINHGRI_mPanPan1
Mhudiblu_PPA_v05128,091,342 - 128,099,886 (+)NCBIMhudiblu_PPA_v0Mhudiblu_PPA_v0panPan3
PanPan1.15134,253,039 - 134,261,581 (+)NCBIpanpan1.1PanPan1.1panPan2
PanPan1.1 Ensembl5134,253,039 - 134,261,581 (+)Ensemblpanpan1.1panPan2
IL4
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.11120,972,693 - 20,981,539 (+)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
CanFam3.1 Ensembl1120,972,690 - 20,981,534 (+)EnsemblCanFam3.1canFam3CanFam3.1
Dog10K_Boxer_Tasha1119,774,149 - 19,783,205 (+)NCBIDog10K_Boxer_Tasha
ROS_Cfam_1.01121,758,633 - 21,767,487 (+)NCBIROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl1121,758,630 - 21,767,482 (+)EnsemblROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.11120,477,129 - 20,485,985 (+)NCBIUMICH_Zoey_3.1
UNSW_CanFamBas_1.01120,324,686 - 20,333,537 (+)NCBIUNSW_CanFamBas_1.0
UU_Cfam_GSD_1.01120,967,178 - 20,976,037 (+)NCBIUU_Cfam_GSD_1.0
IL4
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 Ensembl2134,986,817 - 134,994,365 (+)EnsemblSscrofa11.1susScr11Sscrofa11.1
Sscrofa11.12134,986,817 - 134,994,365 (+)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
Sscrofa10.22140,455,331 - 140,462,879 (+)NCBISscrofa10.2Sscrofa10.2susScr3
IL4
(Chlorocebus sabaeus - green monkey)
Green Monkey AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.12335,492,158 - 35,501,349 (+)NCBIChlSab1.1ChlSab1.1chlSab2
ChlSab1.1 Ensembl2335,492,939 - 35,501,258 (+)EnsemblChlSab1.1ChlSab1.1 EnsemblchlSab2
Vero_WHO_p1.0NW_02366603442,443,750 - 42,449,550 (-)NCBIVero_WHO_p1.0Vero_WHO_p1.0
Il4
(Heterocephalus glaber - naked mole-rat)
Naked Mole-Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla 1.0NW_00462473339,412,800 - 39,420,079 (-)NCBIHetGla_female_1.0HetGla 1.0hetGla2

Variants

.
Variants in IL4
11 total Variants

Clinical Variants
Name Type Condition(s) Position(s) Clinical significance
GRCh38/hg38 5q23.3-33.2(chr5:130860928-155321811)x3 copy number gain See cases [RCV000051193] Chr5:130860928..155321811 [GRCh38]
Chr5:130196621..154701371 [GRCh37]
Chr5:130224520..154681564 [NCBI36]
Chr5:5q23.3-33.2		 pathogenic
GRCh38/hg38 5q31.1(chr5:132301874-134187817)x3 copy number gain Developmental Delay and additional significant developmental and morphological phenotypes referred for genetic testing [RCV000053312]|Developmental delay and additional significant developmental and morphological phenotypes referred for genetic testing [RCV000053312]|See cases [RCV000053312] Chr5:132301874..134187817 [GRCh38]
Chr5:131637567..133523508 [GRCh37]
Chr5:131665466..133551407 [NCBI36]
Chr5:5q31.1		 uncertain significance
GRCh38/hg38 5q23.2-31.1(chr5:126438406-132873967)x1 copy number loss See cases [RCV000052109] Chr5:126438406..132873967 [GRCh38]
Chr5:125774098..132209659 [GRCh37]
Chr5:125801997..132237558 [NCBI36]
Chr5:5q23.2-31.1		 pathogenic
GRCh38/hg38 5q21.3-33.2(chr5:106619588-156124387)x1 copy number loss See cases [RCV000053524] Chr5:106619588..156124387 [GRCh38]
Chr5:105955289..155551397 [GRCh37]
Chr5:105983188..155483975 [NCBI36]
Chr5:5q21.3-33.2		 pathogenic
GRCh38/hg38 5q23.1-31.1(chr5:116677122-132686163)x1 copy number loss See cases [RCV000053525] Chr5:116677122..132686163 [GRCh38]
Chr5:116012818..132021855 [GRCh37]
Chr5:116040717..132049754 [NCBI36]
Chr5:5q23.1-31.1		 pathogenic
GRCh38/hg38 5q31.1(chr5:131626503-135815054)x1 copy number loss See cases [RCV000135442] Chr5:131626503..135815054 [GRCh38]
Chr5:130962196..135150743 [GRCh37]
Chr5:130990095..135178642 [NCBI36]
Chr5:5q31.1		 pathogenic
GRCh38/hg38 5q23.3-33.2(chr5:129847794-153353546)x3 copy number gain See cases [RCV000138808] Chr5:129847794..153353546 [GRCh38]
Chr5:129183487..152733106 [GRCh37]
Chr5:129211386..152713299 [NCBI36]
Chr5:5q23.3-33.2		 pathogenic
GRCh37/hg19 5q15-35.3(chr5:94844077-178830410)x3 copy number gain not provided [RCV000487658] Chr5:94844077..178830410 [GRCh37]
Chr5:5q15-35.3		 likely benign
GRCh37/hg19 5q23.3-33.3(chr5:130125085-157574910)x3 copy number gain See cases [RCV000449349] Chr5:130125085..157574910 [GRCh37]
Chr5:5q23.3-33.3		 pathogenic
GRCh37/hg19 5p15.33-q35.3(chr5:113577-180719789) copy number gain See cases [RCV000510723] Chr5:113577..180719789 [GRCh37]
Chr5:5p15.33-q35.3		 pathogenic
NC_000005.9:g.(?_86400000)_(154000000_?)del deletion Familial adenomatous polyposis 1 [RCV004561496]|Hereditary cancer-predisposing syndrome [RCV000554476] Chr5:86400000..154000000 [GRCh37]
Chr5:5q14.3-33.2		 pathogenic
GRCh37/hg19 5q31.1(chr5:131484039-132998360)x3 copy number gain Blepharophimosis [RCV000677199] Chr5:131484039..132998360 [GRCh37]
Chr5:5q31.1		 uncertain significance
GRCh37/hg19 5q21.3-35.3(chr5:106716357-180687338)x3 copy number gain See cases [RCV000448245] Chr5:106716357..180687338 [GRCh37]
Chr5:5q21.3-35.3		 pathogenic
GRCh37/hg19 5p15.1-q35.2(chr5:17628741-176575720)x1 copy number loss See cases [RCV000511978] Chr5:17628741..176575720 [GRCh37]
Chr5:5p15.1-q35.2		 pathogenic
GRCh37/hg19 5p15.33-q35.3(chr5:113577-180719789)x3 copy number gain See cases [RCV000512039] Chr5:113577..180719789 [GRCh37]
Chr5:5p15.33-q35.3		 pathogenic
GRCh37/hg19 5p15.33-q35.3(chr5:25328-180693344)x3 copy number gain not provided [RCV000744323] Chr5:25328..180693344 [GRCh37]
Chr5:5p15.33-q35.3		 pathogenic
GRCh37/hg19 5p15.33-q35.3(chr5:13648-180905029)x3 copy number gain not provided [RCV000744317] Chr5:13648..180905029 [GRCh37]
Chr5:5p15.33-q35.3		 pathogenic
NM_000589.4(IL4):c.333C>T (p.Asp111=) single nucleotide variant not provided [RCV000964174] Chr5:132679863 [GRCh38]
Chr5:132015555 [GRCh37]
Chr5:5q31.1		 benign
GRCh37/hg19 5q23.2-31.2(chr5:126377719-136270989)x1 copy number loss not provided [RCV000762739] Chr5:126377719..136270989 [GRCh37]
Chr5:5q23.2-31.2		 likely pathogenic
Single allele deletion Neurodevelopmental disorder [RCV000787436] Chr5:14685137..149511942 [GRCh37]
Chr5:5p15.2-q32		 uncertain significance
GRCh37/hg19 5q23.3-31.1(chr5:127800418-134002686) copy number loss Houge-Janssens syndrome 3 [RCV003236718] Chr5:127800418..134002686 [GRCh37]
Chr5:5q23.3-31.1		 pathogenic
NM_000589.4(IL4):c.331G>A (p.Asp111Asn) single nucleotide variant not specified [RCV004082176] Chr5:132679861 [GRCh38]
Chr5:132015553 [GRCh37]
Chr5:5q31.1		 uncertain significance
NM_000589.4(IL4):c.218C>T (p.Ala73Val) single nucleotide variant not specified [RCV004073830] Chr5:132679748 [GRCh38]
Chr5:132015440 [GRCh37]
Chr5:5q31.1		 uncertain significance
NM_000589.4(IL4):c.301A>C (p.Lys101Gln) single nucleotide variant not specified [RCV004276109] Chr5:132679831 [GRCh38]
Chr5:132015523 [GRCh37]
Chr5:5q31.1		 uncertain significance
NM_000589.4(IL4):c.263G>A (p.Arg88His) single nucleotide variant not specified [RCV004405291] Chr5:132679793 [GRCh38]
Chr5:132015485 [GRCh37]
Chr5:5q31.1		 uncertain significance
GRCh37/hg19 5q23.3-33.3(chr5:130125085-157574910) copy number gain not specified [RCV002053526] Chr5:130125085..157574910 [GRCh37]
Chr5:5q23.3-33.3		 pathogenic
NM_000589.4(IL4):c.290T>C (p.Phe97Ser) single nucleotide variant not specified [RCV004077313] Chr5:132679820 [GRCh38]
Chr5:132015512 [GRCh37]
Chr5:5q31.1		 uncertain significance
NM_000589.4(IL4):c.323A>C (p.Lys108Thr) single nucleotide variant not specified [RCV004265557] Chr5:132679853 [GRCh38]
Chr5:132015545 [GRCh37]
Chr5:5q31.1		 uncertain significance
NM_000589.4(IL4):c.349C>G (p.Leu117Val) single nucleotide variant not specified [RCV004405292] Chr5:132679879 [GRCh38]
Chr5:132015571 [GRCh37]
Chr5:5q31.1		 uncertain significance
NM_000589.4(IL4):c.425C>T (p.Thr142Met) single nucleotide variant not specified [RCV004405293] Chr5:132682550 [GRCh38]
Chr5:132018242 [GRCh37]
Chr5:5q31.1		 uncertain significance
NM_000589.4(IL4):c.436G>C (p.Glu146Gln) single nucleotide variant not specified [RCV005352310] Chr5:132682561 [GRCh38]
Chr5:132018253 [GRCh37]
Chr5:5q31.1		 uncertain significance
NM_000589.4(IL4):c.212G>A (p.Arg71Lys) single nucleotide variant not specified [RCV005352311] Chr5:132679742 [GRCh38]
Chr5:132015434 [GRCh37]
Chr5:5q31.1		 uncertain significance
GRCh37/hg19 5q23.2-31.1(chr5:124864529-134720575)x1 copy number loss not provided [RCV004577463] Chr5:124864529..134720575 [GRCh37]
Chr5:5q23.2-31.1		 pathogenic
NM_000589.4(IL4):c.431T>C (p.Met144Thr) single nucleotide variant not specified [RCV004628070] Chr5:132682556 [GRCh38]
Chr5:132018248 [GRCh37]
Chr5:5q31.1		 uncertain significance
NM_000589.4(IL4):c.246C>G (p.His82Gln) single nucleotide variant not specified [RCV004929242] Chr5:132679776 [GRCh38]
Chr5:132015468 [GRCh37]
Chr5:5q31.1		 uncertain significance
miRNA Target Status (No longer updated)

Predicted Target Of
Summary Value
Count of predictions:349
Count of miRNA genes:302
Interacting mature miRNAs:319
Transcripts:ENST00000231449, ENST00000350025, ENST00000495905
Prediction methods:Miranda, Rnahybrid, Targetscan
Result types:miRGate_prediction

The detailed report is available here: Full Report CSV TAB Printer

miRNA Target Status data imported from miRGate (http://mirgate.bioinfo.cnio.es/).
For more information about miRGate, see PMID:25858286 or access the full paper here.

Markers in Region
GDB:180247  
Human AssemblyChrPosition (strand)SourceJBrowse
GRCh375132,011,499 - 132,011,682UniSTSGRCh37
Build 365132,039,398 - 132,039,581RGDNCBI36
Celera5128,141,629 - 128,141,838RGD
Cytogenetic Map5q31.1UniSTS
HuRef5127,203,801 - 127,203,984UniSTS
GDB:180248  
Human AssemblyChrPosition (strand)SourceJBrowse
GRCh375132,016,253 - 132,016,506UniSTSGRCh37
Build 365132,044,152 - 132,044,405RGDNCBI36
Celera5128,146,409 - 128,146,662RGD
Cytogenetic Map5q31.1UniSTS
HuRef5127,208,555 - 127,208,808UniSTS
PMC324417P1  
Human AssemblyChrPosition (strand)SourceJBrowse
GRCh375132,009,822 - 132,010,176UniSTSGRCh37
Build 365132,037,721 - 132,038,075RGDNCBI36
Celera5128,139,951 - 128,140,305RGD
Cytogenetic Map5q31.1UniSTS
HuRef5127,202,123 - 127,202,477UniSTS
PMC356970P2  
Human AssemblyChrPosition (strand)SourceJBrowse
GRCh375132,009,714 - 132,010,181UniSTSGRCh37
Build 365132,037,613 - 132,038,080RGDNCBI36
Celera5128,139,843 - 128,140,310RGD
Cytogenetic Map5q31.1UniSTS
HuRef5127,202,015 - 127,202,482UniSTS
ECD00749  
Human AssemblyChrPosition (strand)SourceJBrowse
GRCh375132,014,801 - 132,015,692UniSTSGRCh37
Build 365132,042,700 - 132,043,591RGDNCBI36
Celera5128,144,957 - 128,145,848RGD
Cytogenetic Map5q31.1UniSTS
HuRef5127,207,103 - 127,207,994UniSTS
ECD01760  
Human AssemblyChrPosition (strand)SourceJBrowse
GRCh375132,012,899 - 132,013,753UniSTSGRCh37
Build 365132,040,798 - 132,041,652RGDNCBI36
Celera5128,143,055 - 128,143,909RGD
Cytogenetic Map5q31.1UniSTS
HuRef5127,205,201 - 127,206,055UniSTS
ECD02519  
Human AssemblyChrPosition (strand)SourceJBrowse
GRCh375132,012,042 - 132,012,869UniSTSGRCh37
Build 365132,039,941 - 132,040,768RGDNCBI36
Celera5128,142,198 - 128,143,025RGD
Cytogenetic Map5q31.1UniSTS
HuRef5127,204,344 - 127,205,171UniSTS
ECD07045  
Human AssemblyChrPosition (strand)SourceJBrowse
GRCh375132,009,760 - 132,010,452UniSTSGRCh37
Build 365132,037,659 - 132,038,351RGDNCBI36
Celera5128,139,889 - 128,140,581RGD
Cytogenetic Map5q31.1UniSTS
HuRef5127,202,061 - 127,202,753UniSTS
ECD08604  
Human AssemblyChrPosition (strand)SourceJBrowse
GRCh375132,009,040 - 132,009,690UniSTSGRCh37
Build 365132,036,939 - 132,037,589RGDNCBI36
Celera5128,139,169 - 128,139,819RGD
Cytogenetic Map5q31.1UniSTS
HuRef5127,201,341 - 127,201,991UniSTS
ECD08735  
Human AssemblyChrPosition (strand)SourceJBrowse
GRCh375132,010,588 - 132,011,235UniSTSGRCh37
Build 365132,038,487 - 132,039,134RGDNCBI36
Celera5128,140,717 - 128,141,364RGD
Cytogenetic Map5q31.1UniSTS
HuRef5127,202,889 - 127,203,536UniSTS
ECD12380  
Human AssemblyChrPosition (strand)SourceJBrowse
GRCh375132,017,704 - 132,018,249UniSTSGRCh37
Build 365132,045,603 - 132,046,148RGDNCBI36
Celera5128,147,860 - 128,148,405RGD
Cytogenetic Map5q31.1UniSTS
HuRef5127,210,006 - 127,210,551UniSTS
ECD19759  
Human AssemblyChrPosition (strand)SourceJBrowse
GRCh375132,008,397 - 132,008,707UniSTSGRCh37
Build 365132,036,296 - 132,036,606RGDNCBI36
Celera5128,138,527 - 128,138,837RGD
Cytogenetic Map5q31.1UniSTS
HuRef5127,200,699 - 127,201,009UniSTS
ECD20165  
Human AssemblyChrPosition (strand)SourceJBrowse
GRCh375132,014,412 - 132,014,706UniSTSGRCh37
Build 365132,042,311 - 132,042,605RGDNCBI36
Celera5128,144,568 - 128,144,862RGD
Cytogenetic Map5q31.1UniSTS
HuRef5127,206,714 - 127,207,008UniSTS
ECD22217  
Human AssemblyChrPosition (strand)SourceJBrowse
GRCh375132,018,475 - 132,018,700UniSTSGRCh37
Build 365132,046,374 - 132,046,599RGDNCBI36
Celera5128,148,631 - 128,148,856RGD
Cytogenetic Map5q31.1UniSTS
HuRef5127,210,777 - 127,211,002UniSTS
REN71218  
Human AssemblyChrPosition (strand)SourceJBrowse
GRCh375132,008,270 - 132,008,519UniSTSGRCh37
Build 365132,036,169 - 132,036,418RGDNCBI36
Celera5128,138,400 - 128,138,649RGD
Cytogenetic Map5q31.1UniSTS
HuRef5127,200,572 - 127,200,821UniSTS
REN71219  
Human AssemblyChrPosition (strand)SourceJBrowse
GRCh375132,008,448 - 132,008,691UniSTSGRCh37
Build 365132,036,347 - 132,036,590RGDNCBI36
Celera5128,138,578 - 128,138,821RGD
Cytogenetic Map5q31.1UniSTS
HuRef5127,200,750 - 127,200,993UniSTS
REN71220  
Human AssemblyChrPosition (strand)SourceJBrowse
GRCh375132,008,559 - 132,008,807UniSTSGRCh37
Build 365132,036,458 - 132,036,706RGDNCBI36
Celera5128,138,689 - 128,138,937RGD
Cytogenetic Map5q31.1UniSTS
HuRef5127,200,861 - 127,201,109UniSTS
REN71221  
Human AssemblyChrPosition (strand)SourceJBrowse
GRCh375132,008,796 - 132,009,045UniSTSGRCh37
Build 365132,036,695 - 132,036,944RGDNCBI36
Celera5128,138,926 - 128,139,174RGD
Cytogenetic Map5q31.1UniSTS
HuRef5127,201,098 - 127,201,346UniSTS
REN71222  
Human AssemblyChrPosition (strand)SourceJBrowse
GRCh375132,009,044 - 132,009,281UniSTSGRCh37
Build 365132,036,943 - 132,037,180RGDNCBI36
Celera5128,139,173 - 128,139,410RGD
Cytogenetic Map5q31.1UniSTS
HuRef5127,201,345 - 127,201,582UniSTS
REN71223  
Human AssemblyChrPosition (strand)SourceJBrowse
GRCh375132,009,257 - 132,009,517UniSTSGRCh37
Build 365132,037,156 - 132,037,416RGDNCBI36
Celera5128,139,386 - 128,139,646RGD
Cytogenetic Map5q31.1UniSTS
HuRef5127,201,558 - 127,201,818UniSTS
REN71224  
Human AssemblyChrPosition (strand)SourceJBrowse
GRCh375132,009,499 - 132,009,746UniSTSGRCh37
Build 365132,037,398 - 132,037,645RGDNCBI36
Celera5128,139,628 - 128,139,875RGD
Cytogenetic Map5q31.1UniSTS
HuRef5127,201,800 - 127,202,047UniSTS
REN71225  
Human AssemblyChrPosition (strand)SourceJBrowse
GRCh375132,009,738 - 132,009,983UniSTSGRCh37
Build 365132,037,637 - 132,037,882RGDNCBI36
Celera5128,139,867 - 128,140,112RGD
Cytogenetic Map5q31.1UniSTS
HuRef5127,202,039 - 127,202,284UniSTS
REN71226  
Human AssemblyChrPosition (strand)SourceJBrowse
GRCh375132,009,958 - 132,010,189UniSTSGRCh37
Build 365132,037,857 - 132,038,088RGDNCBI36
Celera5128,140,087 - 128,140,318RGD
Cytogenetic Map5q31.1UniSTS
HuRef5127,202,259 - 127,202,490UniSTS
REN71227  
Human AssemblyChrPosition (strand)SourceJBrowse
GRCh375132,010,181 - 132,010,425UniSTSGRCh37
Build 365132,038,080 - 132,038,324RGDNCBI36
Celera5128,140,310 - 128,140,554RGD
Cytogenetic Map5q31.1UniSTS
HuRef5127,202,482 - 127,202,726UniSTS
REN71228  
Human AssemblyChrPosition (strand)SourceJBrowse
GRCh375132,010,423 - 132,010,657UniSTSGRCh37
Build 365132,038,322 - 132,038,556RGDNCBI36
Celera5128,140,552 - 128,140,786RGD
Cytogenetic Map5q31.1UniSTS
HuRef5127,202,724 - 127,202,958UniSTS
REN71229  
Human AssemblyChrPosition (strand)SourceJBrowse
GRCh375132,010,634 - 132,010,894UniSTSGRCh37
Build 365132,038,533 - 132,038,793RGDNCBI36
Celera5128,140,763 - 128,141,023RGD
Cytogenetic Map5q31.1UniSTS
HuRef5127,202,935 - 127,203,195UniSTS
REN71230  
Human AssemblyChrPosition (strand)SourceJBrowse
GRCh375132,010,859 - 132,011,128UniSTSGRCh37
Build 365132,038,758 - 132,039,027RGDNCBI36
Celera5128,140,988 - 128,141,257RGD
Cytogenetic Map5q31.1UniSTS
HuRef5127,203,160 - 127,203,429UniSTS
REN71231  
Human AssemblyChrPosition (strand)SourceJBrowse
GRCh375132,011,057 - 132,011,326UniSTSGRCh37
Build 365132,038,956 - 132,039,225RGDNCBI36
Celera5128,141,186 - 128,141,456RGD
Cytogenetic Map5q31.1UniSTS
HuRef5127,203,358 - 127,203,628UniSTS
REN71232  
Human AssemblyChrPosition (strand)SourceJBrowse
GRCh375132,011,296 - 132,011,548UniSTSGRCh37
Build 365132,039,195 - 132,039,447RGDNCBI36
Celera5128,141,426 - 128,141,678RGD
Cytogenetic Map5q31.1UniSTS
HuRef5127,203,598 - 127,203,850UniSTS
REN71233  
Human AssemblyChrPosition (strand)SourceJBrowse
GRCh375132,011,527 - 132,011,762UniSTSGRCh37
Build 365132,039,426 - 132,039,661RGDNCBI36
Celera5128,141,657 - 128,141,918RGD
Cytogenetic Map5q31.1UniSTS
HuRef5127,203,829 - 127,204,064UniSTS
REN71234  
Human AssemblyChrPosition (strand)SourceJBrowse
GRCh375132,011,739 - 132,011,997UniSTSGRCh37
Build 365132,039,638 - 132,039,896RGDNCBI36
Celera5128,141,895 - 128,142,153RGD
Cytogenetic Map5q31.1UniSTS
HuRef5127,204,041 - 127,204,299UniSTS
REN71235  
Human AssemblyChrPosition (strand)SourceJBrowse
GRCh375132,011,977 - 132,012,222UniSTSGRCh37
Build 365132,039,876 - 132,040,121RGDNCBI36
Celera5128,142,133 - 128,142,378RGD
Cytogenetic Map5q31.1UniSTS
HuRef5127,204,279 - 127,204,524UniSTS
REN71236  
Human AssemblyChrPosition (strand)SourceJBrowse
GRCh375132,012,199 - 132,012,449UniSTSGRCh37
Build 365132,040,098 - 132,040,348RGDNCBI36
Celera5128,142,355 - 128,142,605RGD
Cytogenetic Map5q31.1UniSTS
HuRef5127,204,501 - 127,204,751UniSTS
REN71237  
Human AssemblyChrPosition (strand)SourceJBrowse
GRCh375132,012,426 - 132,012,655UniSTSGRCh37
Build 365132,040,325 - 132,040,554RGDNCBI36
Celera5128,142,582 - 128,142,811RGD
Cytogenetic Map5q31.1UniSTS
HuRef5127,204,728 - 127,204,957UniSTS
REN71238  
Human AssemblyChrPosition (strand)SourceJBrowse
GRCh375132,012,631 - 132,012,878UniSTSGRCh37
Build 365132,040,530 - 132,040,777RGDNCBI36
Celera5128,142,787 - 128,143,034RGD
Cytogenetic Map5q31.1UniSTS
HuRef5127,204,933 - 127,205,180UniSTS
REN71239  
Human AssemblyChrPosition (strand)SourceJBrowse
GRCh375132,012,848 - 132,013,096UniSTSGRCh37
Build 365132,040,747 - 132,040,995RGDNCBI36
Celera5128,143,004 - 128,143,252RGD
Cytogenetic Map5q31.1UniSTS
HuRef5127,205,150 - 127,205,398UniSTS
REN71240  
Human AssemblyChrPosition (strand)SourceJBrowse
GRCh375132,013,076 - 132,013,301UniSTSGRCh37
Build 365132,040,975 - 132,041,200RGDNCBI36
Celera5128,143,232 - 128,143,457RGD
Cytogenetic Map5q31.1UniSTS
HuRef5127,205,378 - 127,205,603UniSTS
REN71241  
Human AssemblyChrPosition (strand)SourceJBrowse
GRCh375132,013,269 - 132,013,516UniSTSGRCh37
Build 365132,041,168 - 132,041,415RGDNCBI36
Celera5128,143,425 - 128,143,672RGD
Cytogenetic Map5q31.1UniSTS
HuRef5127,205,571 - 127,205,818UniSTS
REN71242  
Human AssemblyChrPosition (strand)SourceJBrowse
GRCh375132,013,496 - 132,013,743UniSTSGRCh37
Build 365132,041,395 - 132,041,642RGDNCBI36
Celera5128,143,652 - 128,143,899RGD
Cytogenetic Map5q31.1UniSTS
HuRef5127,205,798 - 127,206,045UniSTS
REN71243  
Human AssemblyChrPosition (strand)SourceJBrowse
GRCh375132,013,729 - 132,013,972UniSTSGRCh37
Build 365132,041,628 - 132,041,871RGDNCBI36
Celera5128,143,885 - 128,144,128RGD
Cytogenetic Map5q31.1UniSTS
HuRef5127,206,031 - 127,206,274UniSTS
REN71244  
Human AssemblyChrPosition (strand)SourceJBrowse
GRCh375132,013,902 - 132,014,147UniSTSGRCh37
Build 365132,041,801 - 132,042,046RGDNCBI36
Celera5128,144,058 - 128,144,303RGD
Cytogenetic Map5q31.1UniSTS
HuRef5127,206,204 - 127,206,449UniSTS
REN71245  
Human AssemblyChrPosition (strand)SourceJBrowse
GRCh375132,014,105 - 132,014,353UniSTSGRCh37
Build 365132,042,004 - 132,042,252RGDNCBI36
Celera5128,144,261 - 128,144,509RGD
Cytogenetic Map5q31.1UniSTS
HuRef5127,206,407 - 127,206,655UniSTS
REN71246  
Human AssemblyChrPosition (strand)SourceJBrowse
GRCh375132,014,327 - 132,014,593UniSTSGRCh37
Build 365132,042,226 - 132,042,492RGDNCBI36
Celera5128,144,483 - 128,144,749RGD
Cytogenetic Map5q31.1UniSTS
HuRef5127,206,629 - 127,206,895UniSTS
REN71247  
Human AssemblyChrPosition (strand)SourceJBrowse
GRCh375132,014,580 - 132,014,832UniSTSGRCh37
Build 365132,042,479 - 132,042,731RGDNCBI36
Celera5128,144,736 - 128,144,988RGD
Cytogenetic Map5q31.1UniSTS
HuRef5127,206,882 - 127,207,134UniSTS
REN71248  
Human AssemblyChrPosition (strand)SourceJBrowse
GRCh375132,014,805 - 132,015,057UniSTSGRCh37
Build 365132,042,704 - 132,042,956RGDNCBI36
Celera5128,144,961 - 128,145,213RGD
Cytogenetic Map5q31.1UniSTS
HuRef5127,207,107 - 127,207,359UniSTS
REN71249  
Human AssemblyChrPosition (strand)SourceJBrowse
GRCh375132,015,038 - 132,015,276UniSTSGRCh37
Build 365132,042,937 - 132,043,175RGDNCBI36
Celera5128,145,194 - 128,145,432RGD
Cytogenetic Map5q31.1UniSTS
HuRef5127,207,340 - 127,207,578UniSTS
REN71250  
Human AssemblyChrPosition (strand)SourceJBrowse
GRCh375132,015,256 - 132,015,480UniSTSGRCh37
Build 365132,043,155 - 132,043,379RGDNCBI36
Celera5128,145,412 - 128,145,636RGD
Cytogenetic Map5q31.1UniSTS
HuRef5127,207,558 - 127,207,782UniSTS
REN71251  
Human AssemblyChrPosition (strand)SourceJBrowse
GRCh375132,015,454 - 132,015,701UniSTSGRCh37
Build 365132,043,353 - 132,043,600RGDNCBI36
Celera5128,145,610 - 128,145,857RGD
Cytogenetic Map5q31.1UniSTS
HuRef5127,207,756 - 127,208,003UniSTS
REN71252  
Human AssemblyChrPosition (strand)SourceJBrowse
GRCh375132,015,632 - 132,015,859UniSTSGRCh37
Build 365132,043,531 - 132,043,758RGDNCBI36
Celera5128,145,788 - 128,146,015RGD
Cytogenetic Map5q31.1UniSTS
HuRef5127,207,934 - 127,208,161UniSTS
REN71253  
Human AssemblyChrPosition (strand)SourceJBrowse
GRCh375132,015,850 - 132,016,110UniSTSGRCh37
Build 365132,043,749 - 132,044,009RGDNCBI36
Celera5128,146,006 - 128,146,266RGD
Cytogenetic Map5q31.1UniSTS
HuRef5127,208,152 - 127,208,412UniSTS
REN71254  
Human AssemblyChrPosition (strand)SourceJBrowse
GRCh375132,016,057 - 132,016,290UniSTSGRCh37
Build 365132,043,956 - 132,044,189RGDNCBI36
Celera5128,146,213 - 128,146,446RGD
Cytogenetic Map5q31.1UniSTS
HuRef5127,208,359 - 127,208,592UniSTS
REN71255  
Human AssemblyChrPosition (strand)SourceJBrowse
GRCh375132,016,265 - 132,016,515UniSTSGRCh37
Build 365132,044,164 - 132,044,414RGDNCBI36
Celera5128,146,421 - 128,146,671RGD
Cytogenetic Map5q31.1UniSTS
HuRef5127,208,567 - 127,208,817UniSTS
REN71256  
Human AssemblyChrPosition (strand)SourceJBrowse
GRCh375132,016,495 - 132,016,758UniSTSGRCh37
Build 365132,044,394 - 132,044,657RGDNCBI36
Celera5128,146,651 - 128,146,914RGD
Cytogenetic Map5q31.1UniSTS
HuRef5127,208,797 - 127,209,060UniSTS
REN71257  
Human AssemblyChrPosition (strand)SourceJBrowse
GRCh375132,016,711 - 132,016,964UniSTSGRCh37
Build 365132,044,610 - 132,044,863RGDNCBI36
Celera5128,146,867 - 128,147,120RGD
Cytogenetic Map5q31.1UniSTS
HuRef5127,209,013 - 127,209,266UniSTS
REN71258  
Human AssemblyChrPosition (strand)SourceJBrowse
GRCh375132,016,960 - 132,017,210UniSTSGRCh37
Build 365132,044,859 - 132,045,109RGDNCBI36
Celera5128,147,116 - 128,147,366RGD
Cytogenetic Map5q31.1UniSTS
HuRef5127,209,262 - 127,209,512UniSTS
REN71259  
Human AssemblyChrPosition (strand)SourceJBrowse
GRCh375132,017,187 - 132,017,447UniSTSGRCh37
Build 365132,045,086 - 132,045,346RGDNCBI36
Celera5128,147,343 - 128,147,603RGD
Cytogenetic Map5q31.1UniSTS
HuRef5127,209,489 - 127,209,749UniSTS
REN71260  
Human AssemblyChrPosition (strand)SourceJBrowse
GRCh375132,017,443 - 132,017,674UniSTSGRCh37
Build 365132,045,342 - 132,045,573RGDNCBI36
Celera5128,147,599 - 128,147,830RGD
Cytogenetic Map5q31.1UniSTS
HuRef5127,209,745 - 127,209,976UniSTS
REN71261  
Human AssemblyChrPosition (strand)SourceJBrowse
GRCh375132,017,665 - 132,017,889UniSTSGRCh37
Build 365132,045,564 - 132,045,788RGDNCBI36
Celera5128,147,821 - 128,148,045RGD
Cytogenetic Map5q31.1UniSTS
HuRef5127,209,967 - 127,210,191UniSTS
REN71262  
Human AssemblyChrPosition (strand)SourceJBrowse
GRCh375132,017,848 - 132,018,099UniSTSGRCh37
Build 365132,045,747 - 132,045,998RGDNCBI36
Celera5128,148,004 - 128,148,255RGD
Cytogenetic Map5q31.1UniSTS
HuRef5127,210,150 - 127,210,401UniSTS
REN71263  
Human AssemblyChrPosition (strand)SourceJBrowse
GRCh375132,018,036 - 132,018,285UniSTSGRCh37
Build 365132,045,935 - 132,046,184RGDNCBI36
Celera5128,148,192 - 128,148,441RGD
Cytogenetic Map5q31.1UniSTS
HuRef5127,210,338 - 127,210,587UniSTS
REN71264  
Human AssemblyChrPosition (strand)SourceJBrowse
GRCh375132,018,253 - 132,018,502UniSTSGRCh37
Build 365132,046,152 - 132,046,401RGDNCBI36
Celera5128,148,409 - 128,148,658RGD
Cytogenetic Map5q31.1UniSTS
HuRef5127,210,555 - 127,210,804UniSTS
REN71265  
Human AssemblyChrPosition (strand)SourceJBrowse
GRCh375132,018,479 - 132,018,739UniSTSGRCh37
Build 365132,046,378 - 132,046,638RGDNCBI36
Celera5128,148,635 - 128,148,895RGD
Cytogenetic Map5q31.1UniSTS
HuRef5127,210,781 - 127,211,041UniSTS
stSG601440  
Human AssemblyChrPosition (strand)SourceJBrowse
GRCh375132,007,991 - 132,009,106UniSTSGRCh37
Build 365132,035,890 - 132,037,005RGDNCBI36
Celera5128,138,121 - 128,139,235RGD
HuRef5127,200,293 - 127,201,407UniSTS
stSG601441  
Human AssemblyChrPosition (strand)SourceJBrowse
GRCh375132,009,087 - 132,010,155UniSTSGRCh37
Build 365132,036,986 - 132,038,054RGDNCBI36
Celera5128,139,216 - 128,140,284RGD
HuRef5127,201,388 - 127,202,456UniSTS
stSG601442  
Human AssemblyChrPosition (strand)SourceJBrowse
GRCh375132,010,134 - 132,011,221UniSTSGRCh37
Build 365132,038,033 - 132,039,120RGDNCBI36
Celera5128,140,263 - 128,141,350RGD
HuRef5127,202,435 - 127,203,522UniSTS
stSG601443  
Human AssemblyChrPosition (strand)SourceJBrowse
GRCh375132,011,216 - 132,012,677UniSTSGRCh37
Build 365132,039,115 - 132,040,576RGDNCBI36
Celera5128,141,345 - 128,142,833RGD
HuRef5127,203,517 - 127,204,979UniSTS
stSG601444  
Human AssemblyChrPosition (strand)SourceJBrowse
GRCh375132,012,660 - 132,013,920UniSTSGRCh37
Build 365132,040,559 - 132,041,819RGDNCBI36
Celera5128,142,816 - 128,144,076RGD
HuRef5127,204,962 - 127,206,222UniSTS
stSG601445  
Human AssemblyChrPosition (strand)SourceJBrowse
GRCh375132,013,901 - 132,015,366UniSTSGRCh37
Build 365132,041,800 - 132,043,265RGDNCBI36
Celera5128,144,057 - 128,145,522RGD
HuRef5127,206,203 - 127,207,668UniSTS
stSG601446  
Human AssemblyChrPosition (strand)SourceJBrowse
GRCh375132,014,694 - 132,015,693UniSTSGRCh37
Build 365132,042,593 - 132,043,592RGDNCBI36
Celera5128,144,850 - 128,145,849RGD
HuRef5127,206,996 - 127,207,995UniSTS
stSG601447  
Human AssemblyChrPosition (strand)SourceJBrowse
GRCh375132,017,477 - 132,018,532UniSTSGRCh37
Build 365132,045,376 - 132,046,431RGDNCBI36
Celera5128,147,633 - 128,148,688RGD
HuRef5127,209,779 - 127,210,834UniSTS
IL4  
Human AssemblyChrPosition (strand)SourceJBrowse
GRCh375132,009,618 - 132,009,767UniSTSGRCh37
Build 365132,037,517 - 132,037,666RGDNCBI36
Celera5128,139,747 - 128,139,896RGD
HuRef5127,201,919 - 127,202,068UniSTS
GDB:456299  
Human AssemblyChrPosition (strand)SourceJBrowse
Cytogenetic Map5q31.1UniSTS
GDB:207332  
Human AssemblyChrPosition (strand)SourceJBrowse
Cytogenetic Map5q31.1UniSTS


Expression

RNA-SEQ Expression

adipose tissue
alimentary part of gastrointestinal system
appendage
circulatory system
ectoderm
endocrine system
endoderm
entire extraembryonic component
exocrine system
hemolymphoid system
hepatobiliary system
integumental system
mesenchyme
mesoderm
musculoskeletal system
nervous system
renal system
reproductive system
respiratory system
sensory system
833 1410 1728 1459 3204 1249 1624 2 283 1367 169 1650 4413 4425 13 2321 638 1486 1223 120

Sequence

Nucleotide Sequences
RefSeq Transcripts NG_023252 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  NM_000589 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  NM_001354990 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  NM_172348 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
GenBank Nucleotide AB102862 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AC004039 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AF043336 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AF395008 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AF465829 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AM937235 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  BC066277 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  BC066278 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  BC067514 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  BC067515 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  BC070123 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  CD640452 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  CH471062 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  CP068273 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  CS255762 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  EF173851 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  FB507239 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  FJ807883 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  GQ892002 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  GQ892003 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  GQ892004 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  GQ892005 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  GQ892006 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  GQ892007 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  GQ892008 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  GQ892009 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  GQ892010 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  GQ892011 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  GQ892012 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  GQ892013 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  GQ892014 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  GQ892015 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  GQ892016 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  GQ892017 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  HC679221 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  HH829894 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  JX878389 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  M13982 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  M23442 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  X06750 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  X81851 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles

Ensembl Acc Id: ENST00000231449   ⟹   ENSP00000231449
Type: CODING
Position:
Human AssemblyChrPosition (strand)Source
GRCh38.p14 Ensembl5132,673,989 - 132,682,678 (+)Ensembl
Ensembl Acc Id: ENST00000350025   ⟹   ENSP00000325190
Type: CODING
Position:
Human AssemblyChrPosition (strand)Source
GRCh38.p14 Ensembl5132,674,051 - 132,682,587 (+)Ensembl
Ensembl Acc Id: ENST00000495905
Type: CODING
Position:
Human AssemblyChrPosition (strand)Source
GRCh38.p14 Ensembl5132,674,358 - 132,679,869 (+)Ensembl
Ensembl Acc Id: ENST00000622422   ⟹   ENSP00000480581
Type: CODING
Position:
Human AssemblyChrPosition (strand)Source
GRCh38.p14 Ensembl5132,673,986 - 132,682,676 (+)Ensembl
RefSeq Acc Id: NM_000589   ⟹   NP_000580
RefSeq Status: REVIEWED
Type: CODING
Position:
Human AssemblyChrPosition (strand)Source
GRCh385132,673,989 - 132,682,678 (+)NCBI
GRCh375132,009,678 - 132,018,370 (+)NCBI
Build 365132,037,272 - 132,046,267 (+)NCBI Archive
HuRef5127,201,979 - 127,210,672 (+)NCBI
CHM1_15131,442,973 - 131,451,670 (+)NCBI
T2T-CHM13v2.05133,193,788 - 133,202,478 (+)NCBI
Sequence:
RefSeq Acc Id: NM_001354990   ⟹   NP_001341919
RefSeq Status: REVIEWED
Type: CODING
Position:
Human AssemblyChrPosition (strand)Source
GRCh385132,673,989 - 132,682,678 (+)NCBI
T2T-CHM13v2.05133,193,788 - 133,202,478 (+)NCBI
Sequence:
RefSeq Acc Id: NM_172348   ⟹   NP_758858
RefSeq Status: REVIEWED
Type: CODING
Position:
Human AssemblyChrPosition (strand)Source
GRCh385132,673,989 - 132,682,678 (+)NCBI
GRCh375132,009,678 - 132,018,370 (+)NCBI
Build 365132,037,272 - 132,046,267 (+)NCBI Archive
HuRef5127,201,979 - 127,210,672 (+)NCBI
CHM1_15131,442,973 - 131,451,670 (+)NCBI
T2T-CHM13v2.05133,193,788 - 133,202,478 (+)NCBI
Sequence:
Protein Sequences
Protein RefSeqs NP_000580 (Get FASTA)   NCBI Sequence Viewer  
  NP_001341919 (Get FASTA)   NCBI Sequence Viewer  
  NP_758858 (Get FASTA)   NCBI Sequence Viewer  
GenBank Protein AAA59149 (Get FASTA)   NCBI Sequence Viewer  
  AAA59150 (Get FASTA)   NCBI Sequence Viewer  
  AAC03537 (Get FASTA)   NCBI Sequence Viewer  
  AAH66277 (Get FASTA)   NCBI Sequence Viewer  
  AAH67514 (Get FASTA)   NCBI Sequence Viewer  
  AAH67515 (Get FASTA)   NCBI Sequence Viewer  
  AAH70123 (Get FASTA)   NCBI Sequence Viewer  
  AAK71324 (Get FASTA)   NCBI Sequence Viewer  
  ABM53124 (Get FASTA)   NCBI Sequence Viewer  
  ADD60204 (Get FASTA)   NCBI Sequence Viewer  
  ADN03408 (Get FASTA)   NCBI Sequence Viewer  
  ADN03409 (Get FASTA)   NCBI Sequence Viewer  
  ADN03410 (Get FASTA)   NCBI Sequence Viewer  
  ADN03411 (Get FASTA)   NCBI Sequence Viewer  
  ADN03412 (Get FASTA)   NCBI Sequence Viewer  
  ADN03413 (Get FASTA)   NCBI Sequence Viewer  
  ADN03414 (Get FASTA)   NCBI Sequence Viewer  
  ADN03415 (Get FASTA)   NCBI Sequence Viewer  
  ADN03416 (Get FASTA)   NCBI Sequence Viewer  
  ADN03417 (Get FASTA)   NCBI Sequence Viewer  
  ADN03418 (Get FASTA)   NCBI Sequence Viewer  
  ADN03419 (Get FASTA)   NCBI Sequence Viewer  
  ADN03420 (Get FASTA)   NCBI Sequence Viewer  
  ADN03421 (Get FASTA)   NCBI Sequence Viewer  
  ADN03422 (Get FASTA)   NCBI Sequence Viewer  
  ADN03423 (Get FASTA)   NCBI Sequence Viewer  
  AGM38212 (Get FASTA)   NCBI Sequence Viewer  
  BAD89396 (Get FASTA)   NCBI Sequence Viewer  
  CAA29925 (Get FASTA)   NCBI Sequence Viewer  
  CAA57444 (Get FASTA)   NCBI Sequence Viewer  
  CAJ75955 (Get FASTA)   NCBI Sequence Viewer  
  CAP72493 (Get FASTA)   NCBI Sequence Viewer  
  CAV32874 (Get FASTA)   NCBI Sequence Viewer  
  CBL86566 (Get FASTA)   NCBI Sequence Viewer  
  CBX32734 (Get FASTA)   NCBI Sequence Viewer  
  EAW62322 (Get FASTA)   NCBI Sequence Viewer  
  EAW62323 (Get FASTA)   NCBI Sequence Viewer  
Ensembl Protein ENSP00000231449
  ENSP00000231449.2
  ENSP00000325190
  ENSP00000325190.3
  ENSP00000480581
GenBank Protein P05112 (Get FASTA)   NCBI Sequence Viewer  
RefSeq Acc Id: NP_000580   ⟸   NM_000589
- Peptide Label: isoform 1 precursor
- UniProtKB: Q14630 (UniProtKB/Swiss-Prot),   Q6NZ77 (UniProtKB/Swiss-Prot),   P05112 (UniProtKB/Swiss-Prot),   D4HNR6 (UniProtKB/TrEMBL),   B0JFA2 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: NP_758858   ⟸   NM_172348
- Peptide Label: isoform 2 precursor
- UniProtKB: Q5FC01 (UniProtKB/TrEMBL),   Q9UPB9 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: NP_001341919   ⟸   NM_001354990
- Peptide Label: isoform 3 precursor
- UniProtKB: U3LVN1 (UniProtKB/TrEMBL)
- Sequence:
Ensembl Acc Id: ENSP00000480581   ⟸   ENST00000622422
Ensembl Acc Id: ENSP00000231449   ⟸   ENST00000231449
Ensembl Acc Id: ENSP00000325190   ⟸   ENST00000350025

Protein Structures
Name Modeler Protein Id AA Range Protein Structure
AF-P05112-F1-model_v2 AlphaFold P05112 1-153 view protein structure

Promoters
RGD ID:6850126
Promoter ID:EP26038
Type:single initiation site
Name:HS_IL4
Description:Interleukin-4, B-cell stimulating factor-1, IL4 gene.
SO ACC ID:SO:0000170
Source:EPD (Eukaryotic Promoter Database, http://epd.vital-it.ch/)
Notes:homology_group=Homology group 151; Mammalian interleukin-4
Experiment Methods:Sequencing of a full-length cDNA; Nuclease protection with homologous sequence ladder; experiments; performed with closely related gene
Regulation:helper T (repressed by or weakly expressed in) cells; (induced by or strongly expressed in) antigens
Position:
Human AssemblyChrPosition (strand)Source
Build 365132,037,577 - 132,037,637EPD
RGD ID:6803267
Promoter ID:HG_KWN:51063
Type:Non-CpG
SO ACC ID:SO:0000170
Source:MPROMDB
Tissues & Cell Lines:Lymphoblastoid
Transcripts:NM_000589,   NM_172348,   OTTHUMT00000157346
Position:
Human AssemblyChrPosition (strand)Source
Build 365132,037,721 - 132,038,221 (+)MPROMDB
RGD ID:6870544
Promoter ID:EPDNEW_H8437
Type:initiation region
Name:IL4_1
Description:interleukin 4
SO ACC ID:SO:0000170
Source:EPDNEW (Eukaryotic Promoter Database, http://epd.vital-it.ch/)
Experiment Methods:Single-end sequencing.
Position:
Human AssemblyChrPosition (strand)Source
GRCh385132,673,989 - 132,674,049EPDNEW

Additional Information

Database Acc Id Source(s)
AGR Gene HGNC:6014 AgrOrtholog
COSMIC IL4 COSMIC
Ensembl Genes ENSG00000113520 Ensembl, ENTREZGENE, UniProtKB/Swiss-Prot
Ensembl Transcript ENST00000231449 ENTREZGENE
  ENST00000231449.7 UniProtKB/Swiss-Prot
  ENST00000350025 ENTREZGENE
  ENST00000350025.2 UniProtKB/Swiss-Prot
  ENST00000622422 ENTREZGENE
Gene3D-CATH 1.20.1250.10 UniProtKB/Swiss-Prot
GTEx ENSG00000113520 GTEx
HGNC ID HGNC:6014 ENTREZGENE
Human Proteome Map IL4 Human Proteome Map
InterPro 4_helix_cytokine-like_core UniProtKB/Swiss-Prot
  IL-4 UniProtKB/Swiss-Prot
  IL-4/IL-13 UniProtKB/Swiss-Prot
  IL-4/IL-13_CS UniProtKB/Swiss-Prot
KEGG Report hsa:3565 UniProtKB/Swiss-Prot
NCBI Gene 3565 ENTREZGENE
OMIM 147780 OMIM
PANTHER INTERLEUKIN-4 UniProtKB/Swiss-Prot
  PTHR47401 UniProtKB/Swiss-Prot
Pfam IL4 UniProtKB/Swiss-Prot
PharmGKB PA197 PharmGKB
PIRSF Interleukin_4 UniProtKB/Swiss-Prot
PRINTS INTERLEUKIN4 UniProtKB/Swiss-Prot
PROSITE INTERLEUKIN_4_13 UniProtKB/Swiss-Prot
SMART IL4_13 UniProtKB/Swiss-Prot
Superfamily-SCOP SSF47266 UniProtKB/Swiss-Prot
UniProt B0JFA2 ENTREZGENE, UniProtKB/TrEMBL
  D4HNR6 ENTREZGENE, UniProtKB/TrEMBL
  IL4_HUMAN UniProtKB/Swiss-Prot, ENTREZGENE
  Q14630 ENTREZGENE
  Q5FC01 ENTREZGENE, UniProtKB/TrEMBL
  Q6NWP0_HUMAN UniProtKB/TrEMBL
  Q6NZ77 ENTREZGENE
  Q9UPB9 ENTREZGENE, UniProtKB/TrEMBL
  U3LVN1 ENTREZGENE, UniProtKB/TrEMBL
UniProt Secondary Q14630 UniProtKB/Swiss-Prot
  Q6NZ77 UniProtKB/Swiss-Prot