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Gene: Arhgef15 (Rho guanine nucleotide exchange factor 15) Rattus norvegicus

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Symbol:

Arhgef15

Name:

Rho guanine nucleotide exchange factor 15

RGD ID:

1306961

Description:

Enables guanyl-nucleotide exchange factor activity. Involved in positive regulation of stress fiber assembly and regulation of catalytic activity. Located in cytoplasm. Orthologous to human ARHGEF15 (Rho guanine nucleotide exchange factor 15); PARTICIPATES IN ephrin - ephrin receptor bidirectional signaling axis; INTERACTS WITH 2,3,7,8-tetrachlorodibenzodioxine; 2,6-dinitrotoluene; acrylamide.

Type:

protein-coding

RefSeq Status:

VALIDATED

Previously known as:

E5; ephexin-5; LOC287418; Rho guanine nucleotide exchange factor (GEF) 15

RGD Orthologs

Alliance Orthologs

More Info

more info ...

Latest Assembly:

GRCr8 - GRCr8 Assembly

Position:

Rat Assembly	Chr	Position (strand)	Source	Genome Browsers
Rat Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
GRCr8	10	54,149,372 - 54,162,128 (-)	NCBI		GRCr8
mRatBN7.2	10	53,650,521 - 53,663,269 (-)	NCBI	mRatBN7.2	mRatBN7.2
mRatBN7.2 Ensembl	10	53,650,553 - 53,663,913 (-)	Ensembl		mRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx	10	58,311,746 - 58,324,031 (-)	NCBI	Rnor_SHR	UTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.0	10	57,800,344 - 57,812,630 (-)	NCBI	Rnor_SHRSP	UTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.0	10	53,309,305 - 53,321,725 (-)	NCBI	Rnor_WKY	UTH_Rnor_WKY_Bbb_1.0
Rnor_6.0	10	55,532,097 - 55,545,675 (-)	NCBI	Rnor6.0	Rnor_6.0	rn6	Rnor6.0
Rnor_6.0 Ensembl	10	55,532,077 - 55,544,429 (-)	Ensembl	Rnor6.0		rn6	Rnor6.0
Rnor_5.0	10	55,274,558 - 55,288,124 (-)	NCBI	Rnor5.0	Rnor_5.0	rn5	Rnor5.0
RGSC_v3.4	10	55,703,919 - 55,716,219 (-)	NCBI	RGSC3.4	RGSC_v3.4	rn4	RGSC3.4
RGSC_v3.1	10	55,719,072 - 55,729,109 (-)	NCBI
Celera	10	52,816,914 - 52,829,189 (-)	NCBI		Celera
Cytogenetic Map	10	q24	NCBI

JBrowse:

View Region in Genome Browser (JBrowse)

Model

Object Symbol	Species	Term	Qualifier	Evidence	With	Reference	Notes	Source	Original Reference(s)
Arhgef15	Rat	developmental and epileptic encephalopathy		ISO	ARHGEF15 (Homo sapiens)	8554872	ClinVar Annotator: match by term: Developmental and epileptic encephalopathy	ClinVar	PMID:16199547 more ...
Arhgef15	Rat	Diamond-Blackfan anemia		ISO	ARHGEF15 (Homo sapiens)	8554872	ClinVar Annotator: match by term: Diamond-Blackfan anemia	ClinVar	PMID:20522432 more ...
Arhgef15	Rat	dyskeratosis congenita		ISO	ARHGEF15 (Homo sapiens)	8554872	ClinVar Annotator: match by term: Dyskeratosis congenita	ClinVar	PMID:20522432 more ...
Arhgef15	Rat	early infantile epileptic encephalopathy		ISO	ARHGEF15 (Homo sapiens)	8554872	ClinVar Annotator: match by term: Early infantile epileptic encephalopathy	ClinVar	PMID:16199547 more ...
Arhgef15	Rat	Li-Fraumeni syndrome		ISO	ARHGEF15 (Homo sapiens)	8554872	ClinVar Annotator: match by term: Li-Fraumeni syndrome	ClinVar	PMID:20522432 more ...
Arhgef15	Rat	prostate cancer		ISO	ARHGEF15 (Homo sapiens)	8554872	ClinVar Annotator: match by term: Malignant tumor of prostate	ClinVar	PMID:23265383 and PMID:28492532

Only show annotations with direct experimental evidence (0 objects hidden)

Object Symbol	Species	Term	Qualifier	Evidence	With	Reference	Notes	Source	Original Reference(s)
Arhgef15	Rat	2,2',4,4',5,5'-hexachlorobiphenyl	multiple interactions	ISO	Arhgef15 (Mus musculus)	6480464	[2 more ...	CTD	PMID:25510870
Arhgef15	Rat	2,2',5,5'-tetrachlorobiphenyl	multiple interactions	ISO	Arhgef15 (Mus musculus)	6480464	[2 more ...	CTD	PMID:25510870
Arhgef15	Rat	2,3,7,8-tetrachlorodibenzodioxine	decreases expression	EXP		6480464	Tetrachlorodibenzodioxin results in decreased expression of ARHGEF15 mRNA	CTD	PMID:34747641
Arhgef15	Rat	2,6-dinitrotoluene	affects expression	EXP		6480464	2 and 6-dinitrotoluene affects the expression of ARHGEF15 mRNA	CTD	PMID:21346803
Arhgef15	Rat	4,4'-sulfonyldiphenol	increases expression	ISO	Arhgef15 (Mus musculus)	6480464	bisphenol S results in increased expression of ARHGEF15 mRNA	CTD	PMID:30951980
Arhgef15	Rat	4,4'-sulfonyldiphenol	increases methylation	ISO	Arhgef15 (Mus musculus)	6480464	bisphenol S results in increased methylation of ARHGEF15 exon	CTD	PMID:33297965
Arhgef15	Rat	4-hydroxyphenyl retinamide	increases expression	ISO	Arhgef15 (Mus musculus)	6480464	Fenretinide results in increased expression of ARHGEF15 mRNA	CTD	PMID:28973697
Arhgef15	Rat	acrylamide	decreases expression	EXP		6480464	Acrylamide results in decreased expression of ARHGEF15 mRNA	CTD	PMID:28959563
Arhgef15	Rat	benzo[a]pyrene	increases expression	ISO	Arhgef15 (Mus musculus)	6480464	Benzo(a)pyrene results in increased expression of ARHGEF15 mRNA	CTD	PMID:32417428
Arhgef15	Rat	benzo[a]pyrene	increases methylation	ISO	ARHGEF15 (Homo sapiens)	6480464	Benzo(a)pyrene results in increased methylation of ARHGEF15 3' UTR	CTD	PMID:27901495
Arhgef15	Rat	benzo[b]fluoranthene	decreases expression	ISO	Arhgef15 (Mus musculus)	6480464	benzo(b)fluoranthene results in decreased expression of ARHGEF15 mRNA	CTD	PMID:26377693
Arhgef15	Rat	benzo[e]pyrene	decreases methylation	ISO	ARHGEF15 (Homo sapiens)	6480464	benzo(e)pyrene results in decreased methylation of ARHGEF15 3' UTR	CTD	PMID:30157460
Arhgef15	Rat	bisphenol A	decreases expression	EXP		6480464	bisphenol A results in decreased expression of ARHGEF15 mRNA	CTD	PMID:25181051
Arhgef15	Rat	bisphenol F	increases expression	ISO	Arhgef15 (Mus musculus)	6480464	bisphenol F results in increased expression of ARHGEF15 mRNA	CTD	PMID:30951980
Arhgef15	Rat	bisphenol F	decreases expression	ISO	Arhgef15 (Mus musculus)	6480464	bisphenol F results in decreased expression of ARHGEF15 mRNA	CTD	PMID:38685157
Arhgef15	Rat	butanal	increases expression	ISO	ARHGEF15 (Homo sapiens)	6480464	butyraldehyde results in increased expression of ARHGEF15 mRNA	CTD	PMID:26079696
Arhgef15	Rat	cadmium dichloride	decreases expression	EXP		6480464	Cadmium Chloride results in decreased expression of ARHGEF15 mRNA	CTD	PMID:33453195
Arhgef15	Rat	carbon nanotube	decreases expression	ISO	Arhgef15 (Mus musculus)	6480464	Nanotubes and Carbon analog results in decreased expression of ARHGEF15 mRNA	CTD	PMID:25554681
Arhgef15	Rat	carbon nanotube	increases expression	ISO	Arhgef15 (Mus musculus)	6480464	Nanotubes and Carbon results in increased expression of ARHGEF15 mRNA	CTD	PMID:25554681
Arhgef15	Rat	cobalt dichloride	decreases expression	ISO	ARHGEF15 (Homo sapiens)	6480464	cobaltous chloride results in decreased expression of ARHGEF15 mRNA	CTD	PMID:19320972
Arhgef15	Rat	Cuprizon	decreases expression	EXP		6480464	Cuprizone results in decreased expression of ARHGEF15 mRNA	CTD	PMID:26577399
Arhgef15	Rat	dioxygen	multiple interactions	ISO	Arhgef15 (Mus musculus)	6480464	[NFE2L2 protein affects the susceptibility to Oxygen] which affects the expression of ARHGEF15 mRNA	CTD	PMID:30529165
Arhgef15	Rat	doxorubicin	decreases expression	ISO	ARHGEF15 (Homo sapiens)	6480464	Doxorubicin results in decreased expression of ARHGEF15 mRNA	CTD	PMID:29803840
Arhgef15	Rat	epoxiconazole	increases expression	ISO	Arhgef15 (Mus musculus)	6480464	epoxiconazole results in increased expression of ARHGEF15 mRNA	CTD	PMID:35436446
Arhgef15	Rat	genistein	increases expression	ISO	Arhgef15 (Mus musculus)	6480464	Genistein results in increased expression of ARHGEF15 mRNA	CTD	PMID:32186404
Arhgef15	Rat	gentamycin	decreases expression	EXP		6480464	Gentamicins results in decreased expression of ARHGEF15 mRNA	CTD	PMID:22061828
Arhgef15	Rat	hydrogen cyanide	decreases expression	ISO	Arhgef15 (Mus musculus)	6480464	Hydrogen Cyanide results in decreased expression of ARHGEF15 mRNA	CTD	PMID:33914522
Arhgef15	Rat	methamphetamine	increases expression	ISO	Arhgef15 (Mus musculus)	6480464	Methamphetamine results in increased expression of ARHGEF15 mRNA	CTD	PMID:26307267
Arhgef15	Rat	methapyrilene	decreases methylation	ISO	ARHGEF15 (Homo sapiens)	6480464	Methapyrilene results in decreased methylation of ARHGEF15 3' UTR	CTD	PMID:30157460
Arhgef15	Rat	orphenadrine	affects expression	EXP		6480464	Orphenadrine affects the expression of ARHGEF15 mRNA	CTD	PMID:23665939
Arhgef15	Rat	ozone	multiple interactions	ISO	Arhgef15 (Mus musculus)	6480464	[Air Pollutants results in increased abundance of [Ozone co-treated with Soot]] which results in decreased expression of ARHGEF15 mRNA and [Air Pollutants results in increased abundance of Ozone] which results in decreased expression of ARHGEF15 mRNA	CTD	PMID:34911549
Arhgef15	Rat	PCB138	multiple interactions	ISO	Arhgef15 (Mus musculus)	6480464	[2 more ...	CTD	PMID:25510870
Arhgef15	Rat	potassium cyanide	decreases expression	ISO	Arhgef15 (Mus musculus)	6480464	Potassium Cyanide results in decreased expression of ARHGEF15 mRNA	CTD	PMID:33914522
Arhgef15	Rat	silicon dioxide	increases expression	ISO	ARHGEF15 (Homo sapiens)	6480464	Silicon Dioxide analog results in increased expression of ARHGEF15 mRNA	CTD	PMID:25895662
Arhgef15	Rat	titanium dioxide	decreases expression	ISO	Arhgef15 (Mus musculus)	6480464	titanium dioxide results in decreased expression of ARHGEF15 mRNA	CTD	PMID:23557971
Arhgef15	Rat	trichloroethene	decreases expression	EXP		6480464	Trichloroethylene results in decreased expression of ARHGEF15 mRNA	CTD	PMID:33387578
Arhgef15	Rat	triclosan	decreases expression	ISO	ARHGEF15 (Homo sapiens)	6480464	Triclosan results in decreased expression of ARHGEF15 mRNA	CTD	PMID:30510588
Arhgef15	Rat	troglitazone	decreases expression	ISO	Arhgef15 (Mus musculus)	6480464	troglitazone results in decreased expression of ARHGEF15 mRNA	CTD	PMID:28973697

Biological Process

Only show annotations with direct experimental evidence (0 objects hidden)

Object Symbol	Species	Term	Qualifier	Evidence	With	Reference	Notes	Source	Original Reference(s)
Arhgef15	Rat	negative regulation of synapse maturation	involved_in	ISO	Arhgef15 (Mus musculus)	1624291	PMID:21029865	RGD	PMID:21029865
Arhgef15	Rat	negative regulation of synapse maturation	involved_in	IEA	UniProtKB:Q5FWH6 and ensembl:ENSMUSP00000104311	1600115	GO_REF:0000107	Ensembl	GO_REF:0000107
Arhgef15	Rat	positive regulation of stress fiber assembly	involved_in	IDA		8554375	PMID:12775584	UniProt
Arhgef15	Rat	regulation of actin cytoskeleton organization	involved_in	IBA	PANTHER:PTN002656129 more ...	1600115	GO_REF:0000033	GO_Central	GO_REF:0000033
Arhgef15	Rat	regulation of postsynapse assembly	involved_in	ISO	Arhgef15 (Mus musculus)	1624291	PMID:28185854	RGD	PMID:28185854
Arhgef15	Rat	regulation of postsynapse assembly	involved_in	IEA	UniProtKB:Q5FWH6 and ensembl:ENSMUSP00000104311	1600115	GO_REF:0000107	Ensembl	GO_REF:0000107
Arhgef15	Rat	retina vasculature morphogenesis in camera-type eye	acts_upstream_of_or_within	ISO	Arhgef15 (Mus musculus)	1624291	MGI:3812708 PMID:22535667	RGD	PMID:22535667
Arhgef15	Rat	retina vasculature morphogenesis in camera-type eye	acts_upstream_of_or_within	IEA	UniProtKB:Q5FWH6 and ensembl:ENSMUSP00000104311	1600115	GO_REF:0000107	Ensembl	GO_REF:0000107

Cellular Component

Only show annotations with direct experimental evidence (0 objects hidden)

Object Symbol	Species	Term	Qualifier	Evidence	With	Reference	Notes	Source	Original Reference(s)
Arhgef15	Rat	cytoplasm	located_in	IDA		8554375	PMID:12775584	UniProt
Arhgef15	Rat	dendrite	located_in	ISO	Arhgef15 (Mus musculus)	1624291	PMID:21029865	RGD	PMID:21029865
Arhgef15	Rat	dendrite	located_in	IEA	UniProtKB:Q5FWH6 and ensembl:ENSMUSP00000104311	1600115	GO_REF:0000107	Ensembl	GO_REF:0000107
Arhgef15	Rat	glutamatergic synapse	is_active_in	IEA	UniProtKB:Q5FWH6 and ensembl:ENSMUSP00000104311	1600115	GO_REF:0000107	Ensembl	GO_REF:0000107
Arhgef15	Rat	glutamatergic synapse	is_active_in	ISO	Arhgef15 (Mus musculus)	1624291	PMID:28185854	RGD	PMID:28185854
Arhgef15	Rat	postsynapse	is_active_in	ISO	Arhgef15 (Mus musculus)	1624291	PMID:28185854	RGD	PMID:28185854
Arhgef15	Rat	postsynapse	is_active_in	IEA	UniProtKB:Q5FWH6 and ensembl:ENSMUSP00000104311	1600115	GO_REF:0000107	Ensembl	GO_REF:0000107

Molecular Function

Only show annotations with direct experimental evidence (0 objects hidden)

Object Symbol	Species	Term	Qualifier	Evidence	With	Reference	Notes	Source	Original Reference(s)
Arhgef15	Rat	guanyl-nucleotide exchange factor activity	enables	IDA		8554375	PMID:12775584	UniProt
Arhgef15	Rat	guanyl-nucleotide exchange factor activity	enables	IEA	InterPro:IPR000219 and InterPro:IPR047271	1600115	GO_REF:0000002	InterPro	GO_REF:0000002
Arhgef15	Rat	guanyl-nucleotide exchange factor activity	enables	IEA	UniProtKB:Q5FWH6 and ensembl:ENSMUSP00000104311	1600115	GO_REF:0000107	Ensembl	GO_REF:0000107
Arhgef15	Rat	guanyl-nucleotide exchange factor activity	enables	IEA	UniProtKB-KW:KW-0344	1600115	GO_REF:0000043	UniProt	GO_REF:0000043
Arhgef15	Rat	guanyl-nucleotide exchange factor activity	enables	ISO	Arhgef15 (Mus musculus)	1624291	PMID:21029865	RGD	PMID:21029865
Arhgef15	Rat	guanyl-nucleotide exchange factor activity	enables	IEA	UniProtKB:O94989 and ensembl:ENSP00000355026	1600115	GO_REF:0000107	Ensembl	GO_REF:0000107
Arhgef15	Rat	guanyl-nucleotide exchange factor activity	enables	ISO	ARHGEF15 (Homo sapiens)	1624291	PMID:12775584	RGD	PMID:12775584
Arhgef15	Rat	protein binding	enables	ISO	ARHGEF15 (Homo sapiens)	1624291	UniProtKB:P54764 more ...	RGD	PMID:12775584 more ...
Arhgef15	Rat	protein binding	enables	ISO	Arhgef15 (Mus musculus) and PR:Q5FWH6-2	1624291	UniProtKB:P54763 and PMID:21029865	RGD	PMID:21029865
Arhgef15	Rat	protein binding	enables	IPI	UniProtKB:D3ZZK3	8554375	PMID:12775584	UniProt

Imported Annotations - PID (archival)

Object Symbol	Species	Term	Qualifier	Evidence	With	Reference	Notes	Source	Original Reference(s)
Arhgef15	Rat	ephrin - ephrin receptor bidirectional signaling axis		ISO	ARHGEF15 (Homo sapiens)	6484113		PID	PID:200142

#	Reference Title	Reference Citation
1.	Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium.	Gaudet P, etal., Brief Bioinform. 2011 Sep;12(5):449-62. doi: 10.1093/bib/bbr042. Epub 2011 Aug 27.
2.	EphA4-mediated Rho activation via Vsm-RhoGEF expressed specifically in vascular smooth muscle cells.	Ogita H, etal., Circ Res. 2003 Jul 11;93(1):23-31. Epub 2003 May 29.
3.	PID Annotation Import Pipeline	Pipeline to import Pathway Interaction Database annotations from NCI into RGD
4.	ClinVar Automated Import and Annotation Pipeline	RGD automated import pipeline for ClinVar variants, variant-to-disease annotations and gene-to-disease annotations
5.	Data Import for Chemical-Gene Interactions	RGD automated import pipeline for gene-chemical interactions

PMID:21029865	PMID:22535667

Arhgef15
(Rattus norvegicus - Norway rat)

Rat Assembly	Chr	Position (strand)	Source	Genome Browsers
Rat Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
GRCr8	10	54,149,372 - 54,162,128 (-)	NCBI		GRCr8
mRatBN7.2	10	53,650,521 - 53,663,269 (-)	NCBI	mRatBN7.2	mRatBN7.2
mRatBN7.2 Ensembl	10	53,650,553 - 53,663,913 (-)	Ensembl		mRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx	10	58,311,746 - 58,324,031 (-)	NCBI	Rnor_SHR	UTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.0	10	57,800,344 - 57,812,630 (-)	NCBI	Rnor_SHRSP	UTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.0	10	53,309,305 - 53,321,725 (-)	NCBI	Rnor_WKY	UTH_Rnor_WKY_Bbb_1.0
Rnor_6.0	10	55,532,097 - 55,545,675 (-)	NCBI	Rnor6.0	Rnor_6.0	rn6	Rnor6.0
Rnor_6.0 Ensembl	10	55,532,077 - 55,544,429 (-)	Ensembl	Rnor6.0		rn6	Rnor6.0
Rnor_5.0	10	55,274,558 - 55,288,124 (-)	NCBI	Rnor5.0	Rnor_5.0	rn5	Rnor5.0
RGSC_v3.4	10	55,703,919 - 55,716,219 (-)	NCBI	RGSC3.4	RGSC_v3.4	rn4	RGSC3.4
RGSC_v3.1	10	55,719,072 - 55,729,109 (-)	NCBI
Celera	10	52,816,914 - 52,829,189 (-)	NCBI		Celera
Cytogenetic Map	10	q24	NCBI

ARHGEF15
(Homo sapiens - human)

Human Assembly	Chr	Position (strand)	Source	Genome Browsers
Human Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
GRCh38	17	8,310,241 - 8,322,511 (+)	NCBI	GRCh38	GRCh38	hg38	GRCh38
GRCh38.p14 Ensembl	17	8,310,241 - 8,322,514 (+)	Ensembl	GRCh38		hg38	GRCh38
GRCh37	17	8,213,559 - 8,225,829 (+)	NCBI	GRCh37	GRCh37	hg19	GRCh37
Build 36	17	8,154,315 - 8,166,554 (+)	NCBI	NCBI36	Build 36	hg18	NCBI36
Build 34	17	8,154,314 - 8,166,553	NCBI
Celera	17	8,244,326 - 8,256,604 (+)	NCBI		Celera
Cytogenetic Map	17	p13.1	NCBI
HuRef	17	8,108,796 - 8,121,074 (+)	NCBI		HuRef
CHM1_1	17	8,222,461 - 8,234,738 (+)	NCBI		CHM1_1
T2T-CHM13v2.0	17	8,216,478 - 8,228,747 (+)	NCBI		T2T-CHM13v2.0

Arhgef15
(Mus musculus - house mouse)

Mouse Assembly	Chr	Position (strand)	Source	Genome Browsers
Mouse Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
GRCm39	11	68,819,726 - 68,847,760 (-)	NCBI	GRCm39	GRCm39	mm39
GRCm39 Ensembl	11	68,833,981 - 68,848,306 (-)	Ensembl		GRCm39 Ensembl
GRCm38	11	68,928,900 - 68,956,934 (-)	NCBI	GRCm38	GRCm38	mm10	GRCm38
GRCm38.p6 Ensembl	11	68,943,155 - 68,957,480 (-)	Ensembl	GRCm38		mm10	GRCm38
MGSCv37	11	68,756,656 - 68,770,360 (-)	NCBI	GRCm37	MGSCv37	mm9	NCBIm37
MGSCv36	11	68,759,349 - 68,773,053 (-)	NCBI		MGSCv36	mm8
Celera	11	75,885,590 - 75,899,659 (-)	NCBI		Celera
Cytogenetic Map	11	B3	NCBI
cM Map	11	42.21	NCBI

Arhgef15
(Chinchilla lanigera - long-tailed chinchilla)

Chinchilla Assembly	Chr	Position (strand)	Source	Genome Browsers
Chinchilla Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
ChiLan1.0 Ensembl	NW_004955467	8,587,873 - 8,602,747 (-)	Ensembl	ChiLan1.0
ChiLan1.0	NW_004955467	8,590,217 - 8,603,778 (-)	NCBI	ChiLan1.0	ChiLan1.0

ARHGEF15
(Pan paniscus - bonobo/pygmy chimpanzee)

Bonobo Assembly	Chr	Position (strand)	Source	Genome Browsers
Bonobo Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
NHGRI_mPanPan1-v2	19	65,430,225 - 65,448,985 (-)	NCBI		NHGRI_mPanPan1-v2
NHGRI_mPanPan1	17	70,239,706 - 70,258,476 (-)	NCBI		NHGRI_mPanPan1
Mhudiblu_PPA_v0	17	43,336,764 - 43,349,787 (-)	NCBI	Mhudiblu_PPA_v0	Mhudiblu_PPA_v0	panPan3
PanPan1.1	17	48,070,223 - 48,082,499 (-)	NCBI	panpan1.1	PanPan1.1	panPan2
PanPan1.1 Ensembl	17	48,070,223 - 48,082,499 (-)	Ensembl	panpan1.1		panPan2

ARHGEF15
(Canis lupus familiaris - dog)

Dog Assembly	Chr	Position (strand)	Source	Genome Browsers
Dog Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
CanFam3.1	5	33,096,108 - 33,110,551 (+)	NCBI	CanFam3.1	CanFam3.1	canFam3	CanFam3.1
CanFam3.1 Ensembl	5	33,098,159 - 33,121,083 (+)	Ensembl	CanFam3.1		canFam3	CanFam3.1
Dog10K_Boxer_Tasha	5	33,232,023 - 33,246,695 (+)	NCBI		Dog10K_Boxer_Tasha
ROS_Cfam_1.0	5	33,199,015 - 33,213,954 (+)	NCBI		ROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl	5	33,199,053 - 33,213,946 (+)	Ensembl		ROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.1	5	33,165,967 - 33,180,883 (+)	NCBI		UMICH_Zoey_3.1
UNSW_CanFamBas_1.0	5	33,121,691 - 33,136,319 (+)	NCBI		UNSW_CanFamBas_1.0
UU_Cfam_GSD_1.0	5	33,301,486 - 33,316,166 (+)	NCBI		UU_Cfam_GSD_1.0

Arhgef15
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)

Squirrel Assembly	Chr	Position (strand)	Source	Genome Browsers
Squirrel Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
HiC_Itri_2	NW_024405602	48,057,476 - 48,071,035 (+)	NCBI		HiC_Itri_2
SpeTri2.0 Ensembl	NW_004936595	1,534,717 - 1,543,448 (+)	Ensembl	SpeTri2.0	SpeTri2.0 Ensembl
SpeTri2.0	NW_004936595	1,531,694 - 1,545,206 (+)	NCBI	SpeTri2.0	SpeTri2.0		SpeTri2.0

ARHGEF15
(Sus scrofa - pig)

Pig Assembly	Chr	Position (strand)	Source	Genome Browsers
Pig Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
Sscrofa11.1 Ensembl	12	53,495,453 - 53,506,352 (+)	Ensembl	Sscrofa11.1		susScr11	Sscrofa11.1
Sscrofa11.1	12	53,495,409 - 53,506,373 (+)	NCBI	Sscrofa11.1	Sscrofa11.1	susScr11	Sscrofa11.1
Sscrofa10.2	12	55,970,955 - 55,981,937 (+)	NCBI	Sscrofa10.2	Sscrofa10.2	susScr3

ARHGEF15
(Chlorocebus sabaeus - green monkey)

Green Monkey Assembly	Chr	Position (strand)	Source	Genome Browsers
Green Monkey Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
ChlSab1.1	16	7,674,190 - 7,687,129 (+)	NCBI	ChlSab1.1	ChlSab1.1	chlSab2
ChlSab1.1 Ensembl	16	7,674,577 - 7,687,834 (+)	Ensembl	ChlSab1.1	ChlSab1.1 Ensembl	chlSab2
Vero_WHO_p1.0	NW_023666059	13,712,012 - 13,724,581 (-)	NCBI	Vero_WHO_p1.0	Vero_WHO_p1.0

Arhgef15
(Heterocephalus glaber - naked mole-rat)

Naked Mole-Rat Assembly	Chr	Position (strand)	Source	Genome Browsers
Naked Mole-Rat Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
HetGla_female_1.0 Ensembl	NW_004624786	10,892,422 - 10,901,430 (+)	Ensembl	HetGla_female_1.0	HetGla_female_1.0 Ensembl	hetGla2
HetGla 1.0	NW_004624786	10,872,793 - 10,902,948 (+)	NCBI	HetGla_female_1.0	HetGla 1.0	hetGla2

Variants in Arhgef15
37 total Variants

Predicted Target Of

	Summary Value
Count of predictions:	249
Count of miRNA genes:	161
Interacting mature miRNAs:	193
Transcripts:	ENSRNOT00000067528
Prediction methods:	Miranda, Rnahybrid, Targetscan
Result types:	miRGate_prediction

The detailed report is available here: Full Report CSV TAB Printer

miRNA Target Status data imported from miRGate (http://mirgate.bioinfo.cnio.es/).
For more information about miRGate, see PMID:25858286 or access the full paper here.

The following QTLs overlap with this region.

RGD ID	Symbol	Name	LOD	P Value	Trait	Sub Trait	Chr	Start	Stop	Species
61441	Btemp1	Thermal response to stress QTL 1	4		body temperature trait (VT:0005535)	core body temperature (CMO:0001036)	10	35392457	63642539	Rat
1549846	Scl47	Serum cholesterol level QTL 47	3.6		blood cholesterol amount (VT:0000180)	serum total cholesterol level (CMO:0000363)	10	50574707	95574707	Rat
9589136	Insul27	Insulin level QTL 27	10.46	0.001	blood insulin amount (VT:0001560)	plasma insulin level (CMO:0000342)	10	11474010	56474010	Rat
152025229	Scl83	Serum cholesterol level QTL 83	4.33		blood cholesterol amount (VT:0000180)		10	35710580	68663659	Rat
1578779	Tcas10	Tongue tumor susceptibility QTL 10	3.12		tongue integrity trait (VT:0010553)	number of squamous cell tumors of the tongue with diameter greater than 3 mm (CMO:0001950)	10	31297439	76297439	Rat
152025227	Bw195	Body weight QTL 195	5.73		body mass (VT:0001259)		10	46989699	68663659	Rat
631564	Apr3	Acute phase response QTL 3	3.9		blood interleukin-6 amount (VT:0008595)	plasma interleukin-6 level (CMO:0001927)	10	15275955	60275955	Rat
1298069	Bp168	Blood pressure QTL 168	5.5		blood pressure trait (VT:0000183)	systolic blood pressure (CMO:0000004)	10	26521957	98003205	Rat
2293669	Bmd33	Bone mineral density QTL 33	4.5	0.0001	femur strength trait (VT:0010010)	femoral neck polar moment of inertia (CMO:0001670)	10	49444551	81709989	Rat
152025224	Bw193	Body weight QTL 193	6.47		body mass (VT:0001259)		10	51663405	75085664	Rat
631552	Vetf2	Vascular elastic tissue fragility QTL 2	4.5	0.0002	aorta elastic tissue integrity trait (VT:0010556)	artery internal elastic lamina non-tumorous lesion count (CMO:0001913)	10	41142633	86142633	Rat
631554	Bp133	Blood pressure QTL 133		0.005	arterial blood pressure trait (VT:2000000)	systolic blood pressure (CMO:0000004)	10	743364	63851208	Rat
631557	Bp136	Blood pressure QTL 136		0.003	arterial blood pressure trait (VT:2000000)	systolic blood pressure (CMO:0000004)	10	30632053	75632053	Rat
61325	Aia5	Adjuvant induced arthritis QTL 5		0.01	joint integrity trait (VT:0010548)	joint inflammation composite score (CMO:0000919)	10	23444813	104060283	Rat
1298078	Stresp5	Stress response QTL 5	2.99	0.00025	blood corticosterone amount (VT:0005345)	plasma corticosterone level (CMO:0001173)	10	42045676	104670812	Rat
2293679	Bmd30	Bone mineral density QTL 30	3.5	0.0001	femur mineral mass (VT:0010011)	total volumetric bone mineral density (CMO:0001728)	10	49444551	81709989	Rat
1578762	Toxo1	Toxoplasma gondii resistance QTL 1			brain integrity trait (VT:0010579)	percentage of study population displaying Toxoplasma gondii brain cysts at a point in time (CMO:0002028)	10	52200030	59378278	Rat
2298544	Neuinf9	Neuroinflammation QTL 9	4.6		nervous system integrity trait (VT:0010566)	spinal cord complement component 1, q subcomponent, B chain mRNA level (CMO:0002126)	10	5801990	62146030	Rat
61463	Bp12	Blood pressure QTL 12	6.3	0.0001	arterial blood pressure trait (VT:2000000)	systolic blood pressure (CMO:0000004)	10	41333258	86333258	Rat
8694173	Bw149	Body weight QTL 149	4.38	0.001	body mass (VT:0001259)	body weight gain (CMO:0000420)	10	44441699	89441699	Rat
2300218	Hpcl2	Hepatic cholesterol level QTL 2			liver cholesterol amount (VT:0010498)	liver cholesterol level (CMO:0001597)	10	45029650	95600334	Rat
1554317	Bmd4	Bone mineral density QTL 4	9.4	0.0001	lumbar vertebra mineral mass (VT:0010511)	volumetric bone mineral density (CMO:0001553)	10	19816042	99406971	Rat
1598852	Anxrr19	Anxiety related response QTL 19	5.07		body movement coordination trait (VT:0005424)	number of rearing movements in an experimental apparatus (CMO:0001752)	10	18167841	63167841	Rat
1581497	Esta1	Estrogen-induced thymic atrophy QTL 1			thymus mass (VT:0004954)	thymus wet weight (CMO:0000855)	10	21329805	61345413	Rat
724527	Bp148	Blood pressure QTL 148		0.0001	arterial blood pressure trait (VT:2000000)	mean arterial blood pressure (CMO:0000009)	10	28453136	73453136	Rat
1358897	Stresp6	Stress response QTL 6	4.17	0.022	blood norepinephrine amount (VT:0005663)	plasma norepinephrine level (CMO:0001010)	10	35392267	64155584	Rat
1331762	Rf40	Renal function QTL 40	3.873		kidney blood vessel physiology trait (VT:0100012)	absolute change in renal vascular resistance (CMO:0001900)	10	29299504	64155584	Rat
2300171	Bmd58	Bone mineral density QTL 58	4.9	0.0001	lumbar vertebra mineral mass (VT:0010511)	volumetric bone mineral density (CMO:0001553)	10	26944628	71944628	Rat
61354	Pia10	Pristane induced arthritis QTL 10		0.01	joint integrity trait (VT:0010548)	joint inflammation composite score (CMO:0000919)	10	23444813	104060283	Rat
2301967	Cm73	Cardiac mass QTL 73	4.55		heart left ventricle mass (VT:0007031)	heart left ventricle weight to body weight ratio (CMO:0000530)	10	14487011	89062041	Rat
2303118	Mamtr7	Mammary tumor resistance QTL 7		0.003	mammary gland integrity trait (VT:0010552)	mammary tumor growth rate (CMO:0000344)	10	9658275	104670812	Rat
70188	BpQTLcluster1	Blood pressure QTL cluster 1	4.864		arterial blood pressure trait (VT:2000000)	pulse pressure (CMO:0000292)	1	42323132	87323132	Rat
9590310	Scort19	Serum corticosterone level QTL 19	6.3	0.001	blood corticosterone amount (VT:0005345)	plasma corticosterone level (CMO:0001173)	10	11474010	56474010	Rat
9589030	Epfw9	Epididymal fat weight QTL 9	19.24	0.001	epididymal fat pad mass (VT:0010421)	epididymal fat pad weight to body weight ratio (CMO:0000658)	10	44441699	89441699	Rat
10402859	Bp381	Blood pressure QTL 381		0.002	arterial blood pressure trait (VT:2000000)	mean arterial blood pressure (CMO:0000009)	10	27606468	72606468	Rat
2316949	Gluco60	Glucose level QTL 60	3.7		blood glucose amount (VT:0000188)	blood glucose level (CMO:0000046)	10	14487011	107057807	Rat
2293652	Bmd22	Bone mineral density QTL 22	4.9	0.0001	femur mineral mass (VT:0010011)	total volumetric bone mineral density (CMO:0001728)	10	49444551	81709989	Rat
70198	BpQTLcluster9	Blood pressure QTL cluster 9	2.94		arterial blood pressure trait (VT:2000000)	mean arterial blood pressure (CMO:0000009)	10	42323132	87323132	Rat
1359017	Hrtrt21	Heart rate QTL 21	2.4		heart pumping trait (VT:2000009)	heart rate (CMO:0000002)	10	51772940	96772940	Rat
6893352	Bw100	Body weight QTL 100	0.33	0.6	body mass (VT:0001259)	body weight (CMO:0000012)	1	15906665	60906665	Rat
724556	Pur2	Proteinuria QTL 2	5.5		urine protein amount (VT:0005160)	urine protein level (CMO:0000591)	10	22427500	90627625	Rat
8662860	Vetf10	Vascular elastic tissue fragility QTL 10			artery integrity trait (VT:0010639)	number of ruptures of the internal elastic lamina of the abdominal aorta and iliac arteries (CMO:0002562)	10	6154182	73453136	Rat
61387	Bp1	Blood pressure QTL 1	5.1		arterial blood pressure trait (VT:2000000)	diastolic blood pressure (CMO:0000005)	10	51770177	107211142	Rat
70223	Bp57	Blood pressure QTL 57	5		arterial blood pressure trait (VT:2000000)	systolic blood pressure (CMO:0000004)	10	1	80676123	Rat
1354587	Kidm21	Kidney mass QTL 21	3.3		kidney mass (VT:0002707)	right kidney wet weight (CMO:0000082)	10	15028513	60430477	Rat
6893350	Bw99	Body weight QTL 99	0.87	0.16	body mass (VT:0001259)	body weight (CMO:0000012)	1	15906665	60906665	Rat
2317043	Aia7	Adjuvant induced arthritis QTL 7	3.82		joint integrity trait (VT:0010548)	left rear ankle joint diameter (CMO:0002149)	10	37565079	82565079	Rat
70224	Eae3	Experimental allergic encephalomyelitis QTL 3	4.1		nervous system integrity trait (VT:0010566)	experimental autoimmune encephalomyelitis incidence/prevalence measurement (CMO:0001046)	10	26521957	61345413	Rat
2317042	Aia20	Adjuvant induced arthritis QTL 20	3.38		joint integrity trait (VT:0010548)	right rear ankle joint diameter (CMO:0002150)	10	37565079	82565079	Rat
1331791	Cm31	Cardiac mass QTL 31	3.84606		heart mass (VT:0007028)	heart wet weight (CMO:0000069)	10	29299504	107211142	Rat
2313087	Bmd80	Bone mineral density QTL 80	3.2	0.0001	tibia mineral mass (VT:1000283)	total volumetric bone mineral density (CMO:0001728)	10	19606483	64606483	Rat
70364	Bp72	Blood pressure QTL 72			arterial blood pressure trait (VT:2000000)	mean arterial blood pressure (CMO:0000009)	10	51121100	96121100	Rat
631530	Tls3	T-lymphoma susceptibility QTL 3	0	0.0001	thymus integrity trait (VT:0010555)	percentage of study population developing T-cell lymphomas during a period of time (CMO:0001911)	10	51774612	95600334	Rat
631535	Cm51	Cardiac mass QTL 51	3		heart mass (VT:0007028)	calculated heart weight (CMO:0000073)	10	51786282	91669536	Rat
1576319	Cia29	Collagen induced arthritis QTL 29			joint integrity trait (VT:0010548)	joint inflammation composite score (CMO:0000919)	10	33973921	78973921	Rat
8552805	Bw145	Body weight QTL 145	2.2		body mass (VT:0001259)	change in body weight to body weight ratio (CMO:0002216)	10	41944526	78307017	Rat
631267	Cia20	Collagen induced arthritis QTL 20	3.2		joint integrity trait (VT:0010548)	joint inflammation composite score (CMO:0000919)	10	23444813	104060283	Rat
2293705	Bmd25	Bone mineral density QTL 25	7.1	0.0001	femur mineral mass (VT:0010011)	compact volumetric bone mineral density (CMO:0001730)	10	49444551	81709989	Rat
1576308	Schws1	Schwannoma susceptibility QTL 1		0.0041	nervous system integrity trait (VT:0010566)	percentage of study population developing trigeminal nerve neurilemmomas during a period of time (CMO:0002017)	10	40035094	102359817	Rat
631269	Cia22	Collagen induced arthritis QTL 22	8.9		joint integrity trait (VT:0010548)	joint inflammation composite score (CMO:0000919)	10	40035094	104060283	Rat
631268	Cia21	Collagen induced arthritis QTL 21	3.1		joint integrity trait (VT:0010548)	joint inflammation composite score (CMO:0000919)	10	14487011	104060283	Rat
9590268	Scort13	Serum corticosterone level QTL 13	3.26	0.001	blood corticosterone amount (VT:0005345)	plasma corticosterone level (CMO:0001173)	10	11474010	56474010	Rat
7207811	Bmd90	Bone mineral density QTL 90	5.2		femur size trait (VT:1000369)	femoral neck cross-sectional area (CMO:0001697)	10	49444551	81709989	Rat
1576311	Pia26	Pristane induced arthritis QTL 26			joint integrity trait (VT:0010548)	joint inflammation composite score (CMO:0000919)	10	31224026	75632053	Rat
631270	Cia23	Collagen induced arthritis QTL 23	3.9		joint integrity trait (VT:0010548)	joint inflammation composite score (CMO:0000919)	10	40035094	104060283	Rat
7411614	Foco18	Food consumption QTL 18		0.001	eating behavior trait (VT:0001431)	feed conversion ratio (CMO:0001312)	10	44441699	89441699	Rat
631547	Bp87	Blood pressure QTL 87	4.5		arterial blood pressure trait (VT:2000000)	systolic blood pressure (CMO:0000004)	10	47369470	92369470	Rat
61427	Cia16	Collagen induced arthritis QTL 16	3.2		joint integrity trait (VT:0010548)	joint inflammation composite score (CMO:0000919)	10	6357896	96121100	Rat
6893342	Cm78	Cardiac mass QTL 78	0.1	0.88	heart mass (VT:0007028)	heart weight to body weight ratio (CMO:0000074)	10	42876766	79813922	Rat
2292441	Bp308	Blood pressure QTL 308			arterial blood pressure trait (VT:2000000)	mean arterial blood pressure (CMO:0000009)	10	27606468	72606468	Rat
2313055	Bw96	Body weight QTL 96	3.6	0.0001	body mass (VT:0001259)	body weight (CMO:0000012)	10	19606483	64606483	Rat
631542	Bp82	Blood pressure QTL 82	6.8		arterial blood pressure trait (VT:2000000)	systolic blood pressure (CMO:0000004)	10	26521957	98952741	Rat

RH131949

Rat Assembly	Chr	Position (strand)	Source	JBrowse
mRatBN7.2	10	53,650,712 - 53,650,900 (+)	MAPPER	mRatBN7.2
Rnor_6.0	10	55,532,289 - 55,532,476	NCBI	Rnor6.0
Rnor_5.0	10	55,274,776 - 55,274,963	UniSTS	Rnor5.0
RGSC_v3.4	10	55,704,079 - 55,704,266	UniSTS	RGSC3.4
Celera	10	52,817,074 - 52,817,261	UniSTS
Cytogenetic Map	10	q24	UniSTS

Click on a value in the shaded box below the category label to view a detailed expression data table for that system.

alimentary part of gastrointestinal system	appendage	circulatory system	ectoderm	endocrine system	endoderm	exocrine system	hemolymphoid system	hepatobiliary system	integumental system	mesenchyme	mesoderm	nervous system	renal system	reproductive system	respiratory system
9	11	49	113	91	90	59	25	59	6	218	97	93	45	60	31


RefSeq Transcripts	NM_001414295	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	XM_008767788	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	XM_008767789	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	XM_008767790	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	XM_008767791	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	XM_008767793	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	XM_017597083	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	XM_017597084	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	XM_039085436	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	XR_001840036	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	XR_005489733	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	XR_005489734	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	XR_594717	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
GenBank Nucleotide	AC126877	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	CH473948	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	JAXUCZ010000010	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles

Ensembl Acc Id:

ENSRNOT00000067528 ⟹ ENSRNOP00000060721

Type:

CODING

Position:

Rat Assembly	Chr	Position (strand)	Source
mRatBN7.2 Ensembl	10	53,650,553 - 53,662,846 (-)	Ensembl
Rnor_6.0 Ensembl	10	55,532,129 - 55,544,429 (-)	Ensembl

Ensembl Acc Id:

ENSRNOT00000084385 ⟹ ENSRNOP00000068844

Type:

CODING

Position:

Rat Assembly	Chr	Position (strand)	Source
mRatBN7.2 Ensembl	10	53,650,578 - 53,663,913 (-)	Ensembl
Rnor_6.0 Ensembl	10	55,532,077 - 55,543,527 (-)	Ensembl

RefSeq Acc Id:

NM_001414295 ⟹ NP_001401224

RefSeq Status:

VALIDATED

Type:

CODING

Position:

Rat Assembly	Chr	Position (strand)	Source
GRCr8	10	54,149,372 - 54,162,128 (-)	NCBI
mRatBN7.2	10	53,650,521 - 53,663,269 (-)	NCBI

RefSeq Acc Id:

XM_039085436 ⟹ XP_038941364

Type:

CODING

Position:

Rat Assembly	Chr	Position (strand)	Source
GRCr8	10	54,149,372 - 54,160,758 (-)	NCBI
mRatBN7.2	10	53,650,521 - 53,661,930 (-)	NCBI

RefSeq Acc Id:

XR_005489733

Type:

NON-CODING

Position:

Rat Assembly	Chr	Position (strand)	Source
GRCr8	10	54,149,372 - 54,160,758 (-)	NCBI
mRatBN7.2	10	53,650,521 - 53,662,914 (-)	NCBI

RefSeq Acc Id:

XR_005489734

Type:

NON-CODING

Position:

Rat Assembly	Chr	Position (strand)	Source
GRCr8	10	54,152,372 - 54,160,758 (-)	NCBI
mRatBN7.2	10	53,653,519 - 53,662,914 (-)	NCBI


Protein RefSeqs	NP_001401224	(Get FASTA)	NCBI Sequence Viewer
	XP_038941364	(Get FASTA)	NCBI Sequence Viewer
GenBank Protein	EDM04823	(Get FASTA)	NCBI Sequence Viewer
Ensembl Protein	ENSRNOP00000060721.1
	ENSRNOP00000068844
	ENSRNOP00000068844.1

Ensembl Acc Id:

ENSRNOP00000060721 ⟸ ENSRNOT00000067528

Ensembl Acc Id:

ENSRNOP00000068844 ⟸ ENSRNOT00000084385

RefSeq Acc Id:	XP_038941364 ⟸ XM_039085436
- Peptide Label:	isoform X1

RefSeq Acc Id:	NP_001401224 ⟸ NM_001414295
- UniProtKB:	A0A0G2JTU0 (UniProtKB/TrEMBL)

Protein Domains

Name	Modeler	Protein Id	AA Range	Protein Structure
AF-A0A0G2JTU0-F1-model_v2	AlphaFold	A0A0G2JTU0	1-850	view protein structure

eQTL		View at Phenogen
WGCNA		View at Phenogen
Tissue/Strain Expression		View at Phenogen

Database	Acc Id	Source(s)
BioCyc Gene	G2FUF-24616	BioCyc
Ensembl Genes	ENSRNOG00000004566	Ensembl, ENTREZGENE, UniProtKB/TrEMBL
Ensembl Transcript	ENSRNOT00000067528.2	UniProtKB/TrEMBL
	ENSRNOT00000084385	ENTREZGENE
	ENSRNOT00000084385.2	UniProtKB/TrEMBL
	ENSRNOT00000162011	ENTREZGENE
Gene3D-CATH	1.20.900.10	UniProtKB/TrEMBL
	2.30.29.30	UniProtKB/TrEMBL
InterPro	DBL_dom_sf	UniProtKB/TrEMBL
	DH-domain	UniProtKB/TrEMBL
	Ephexin-like	UniProtKB/TrEMBL
	PH_dom-like	UniProtKB/TrEMBL
	PH_ephexin	UniProtKB/TrEMBL
NCBI Gene	287418	ENTREZGENE
PANTHER	GUANINE NUCLEOTIDE EXCHANGE FACTOR	UniProtKB/TrEMBL
	RHO GUANINE NUCLEOTIDE EXCHANGE FACTOR 15	UniProtKB/TrEMBL
Pfam	RhoGEF	UniProtKB/TrEMBL
PhenoGen	Arhgef15	PhenoGen
PROSITE	DH_2	UniProtKB/TrEMBL
RatGTEx	ENSRNOG00000004566	RatGTEx
SMART	RhoGEF	UniProtKB/TrEMBL
Superfamily-SCOP	DH-domain	UniProtKB/TrEMBL
	PH domain-like	UniProtKB/TrEMBL
UniProt	A0A0G2JTU0	ENTREZGENE, UniProtKB/TrEMBL
	D3ZPJ8_RAT	UniProtKB/TrEMBL

Nomenclature History

Date	Current Symbol	Current Name	Previous Symbol	Previous Name	Description	Reference	Status
2015-11-19	Arhgef15	Rho guanine nucleotide exchange factor 15	Arhgef15	Rho guanine nucleotide exchange factor (GEF) 15	Nomenclature updated to reflect human and mouse nomenclature	1299863	APPROVED
2008-04-30	Arhgef15	Rho guanine nucleotide exchange factor (GEF) 15	Arhgef15_predicted	Rho guanine nucleotide exchange factor (GEF) 15 (predicted)	'predicted' is removed	2292626	APPROVED
2005-01-12	Arhgef15_predicted	Rho guanine nucleotide exchange factor (GEF) 15 (predicted)			Symbol and Name status set to approved	70820	APPROVED

Gene Annotator (Functional Annotation) unavailable	Gene Annotator (Annotation Distribution) unavailable	Variant Visualizer (Genomic Variants) unavailable


InterViewer (Protein-Protein Interactions) unavailable	Gviewer (Genome Viewer) unavailable	Variant Visualizer (Damaging Variants) unavailable


Gene Annotator (Annotation Comparison) unavailable	OLGA (Gene List Generator) unavailable
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Imported Disease Annotations - ClinVar

Imported Annotations - PID (archival)