Ttc19 (tetratricopeptide repeat domain 19) - Rat Genome Database

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Gene: Ttc19 (tetratricopeptide repeat domain 19) Rattus norvegicus
Analyze
Symbol: Ttc19
Name: tetratricopeptide repeat domain 19
RGD ID: 1582808
Description: Predicted to be involved in mitochondrial respiratory chain complex III assembly. Predicted to be located in mitochondrion. Predicted to be active in mitochondrial inner membrane. Human ortholog(s) of this gene implicated in mitochondrial complex III deficiency nuclear type 2. Orthologous to human TTC19 (tetratricopeptide repeat domain 19); INTERACTS WITH 2,3,7,8-tetrachlorodibenzodioxine; 6-propyl-2-thiouracil; acetamide.
Type: protein-coding
RefSeq Status: VALIDATED
Previously known as: LOC287389; LOC691506; RGD1311797; similar to RIKEN cDNA 2810460C24; similar to Tetratricopeptide repeat protein 19 (TPR repeat protein 19); tetratricopeptide repeat protein 19; tetratricopeptide repeat protein 19, mitochondrial; TPR repeat protein 19
RGD Orthologs
Human
Mouse
Chinchilla
Bonobo
Dog
Squirrel
Pig
Green Monkey
Naked Mole-Rat
Alliance Orthologs
More Info more info ...
Latest Assembly: GRCr8 - GRCr8 Assembly
Position:
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr81047,469,043 - 47,496,923 (+)NCBIGRCr8
mRatBN7.21046,969,723 - 46,997,607 (+)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl1046,969,727 - 46,997,789 (+)EnsemblmRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx1051,673,517 - 51,701,553 (+)NCBIRnor_SHRUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.01051,164,067 - 51,192,104 (+)NCBIRnor_SHRSPUTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.01046,667,475 - 46,695,511 (+)NCBIRnor_WKYUTH_Rnor_WKY_Bbb_1.0
Rnor_6.01048,599,321 - 48,627,374 (+)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl1048,599,321 - 48,627,374 (+)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.01048,387,826 - 48,415,743 (+)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.41048,450,922 - 48,479,028 (+)NCBIRGSC3.4RGSC_v3.4rn4RGSC3.4
Celera1046,215,636 - 46,243,767 (+)NCBICelera
Cytogenetic Map10q23NCBI
JBrowse: View Region in Genome Browser (JBrowse)
Model


Object Symbol
Species
Term
Qualifier
Evidence
With
Reference
Notes
Source
Original Reference(s)
Ttc19Ratautistic disorder  ISOTTC19 (Homo sapiens)8554872ClinVar Annotator: match by term: AutismClinVarPMID:25741868
Ttc19Ratgenetic disease  ISOTTC19 (Homo sapiens)8554872ClinVar Annotator: match by term: Inborn genetic diseasesClinVarPMID:21278747 more ...
Ttc19Ratmitochondrial complex III deficiency nuclear type 1  ISOTTC19 (Homo sapiens)8554872ClinVar Annotator: match by term: Mitochondrial complex III deficiency nuclear type 1ClinVarPMID:25741868
Ttc19Ratmitochondrial complex III deficiency nuclear type 2  ISOTTC19 (Homo sapiens)8554872ClinVar more ...ClinVarPMID:17576681 more ...
Ttc19Ratmitochondrial metabolism disease  ISOTTC19 (Homo sapiens)8554872ClinVar Annotator: match by term: Mitochondrial diseaseClinVar 
Object Symbol
Species
Term
Qualifier
Evidence
With
Reference
Notes
Source
Original Reference(s)
Ttc19Ratinfertility  ISOTTC19 (Homo sapiens)11554173CTD Direct Evidence: marker/mechanismCTDPMID:21278747
Ttc19Ratmitochondrial complex III deficiency nuclear type 1  ISOTTC19 (Homo sapiens)11554173CTD Direct Evidence: marker/mechanismCTDPMID:21278747
Ttc19Ratnervous system disease  ISOTTC19 (Homo sapiens)11554173CTD Direct Evidence: marker/mechanismCTDPMID:21278747
Ttc19Ratneurodegenerative disease  ISOTTC19 (Homo sapiens)11554173CTD Direct Evidence: marker/mechanismCTDPMID:21278747
Ttc19RatNeurologic Gait Disorders  ISOTTC19 (Homo sapiens)11554173CTD Direct Evidence: marker/mechanismCTDPMID:21278747
Object Symbol
Species
Term
Qualifier
Evidence
With
Reference
Notes
Source
Original Reference(s)
Ttc19Ratmitochondrial complex III deficiency nuclear type 2  ISOTTC19 (Homo sapiens)7240710 OMIM 

1 to 20 of 47 rows

  
Object Symbol
Species
Term
Qualifier
Evidence
With
Reference
Notes
Source
Original Reference(s)
Ttc19Rat1,2-dimethylhydrazine decreases expressionISOTtc19 (Mus musculus)64804641 and 2-Dimethylhydrazine results in decreased expression of TTC19 mRNACTDPMID:22206623
Ttc19Rat2,3,7,8-tetrachlorodibenzodioxine affects expressionISOTtc19 (Mus musculus)6480464Tetrachlorodibenzodioxin affects the expression of TTC19 mRNACTDPMID:21570461
Ttc19Rat2,3,7,8-tetrachlorodibenzodioxine decreases expressionEXP 6480464Tetrachlorodibenzodioxin results in decreased expression of TTC19 mRNACTDPMID:32109520
Ttc19Rat4,4'-sulfonyldiphenol increases expressionISOTtc19 (Mus musculus)6480464bisphenol S results in increased expression of TTC19 mRNACTDPMID:39298647
Ttc19Rat6-propyl-2-thiouracil increases expressionEXP 6480464Propylthiouracil results in increased expression of TTC19 mRNACTDPMID:30047161
Ttc19Ratacetamide decreases expressionEXP 6480464acetamide results in decreased expression of TTC19 mRNACTDPMID:31881176
Ttc19Ratacrylamide decreases expressionISOTTC19 (Homo sapiens)6480464Acrylamide results in decreased expression of TTC19 mRNACTDPMID:32763439
Ttc19Ratall-trans-retinoic acid decreases expressionISOTTC19 (Homo sapiens)6480464Tretinoin results in decreased expression of TTC19 mRNACTDPMID:33167477
Ttc19Ratamitrole increases expressionEXP 6480464Amitrole results in increased expression of TTC19 mRNACTDPMID:30047161
Ttc19Ratbenzene increases expressionISOTTC19 (Homo sapiens)6480464Benzene results in increased expression of TTC19 mRNACTDPMID:19162166
Ttc19Ratbisphenol A decreases expressionEXP 6480464bisphenol A results in decreased expression of TTC19 mRNACTDPMID:25181051
Ttc19Ratbisphenol A increases methylationISOTTC19 (Homo sapiens)6480464bisphenol A results in increased methylation of TTC19 geneCTDPMID:31601247
Ttc19Ratbisphenol A multiple interactionsISOTTC19 (Homo sapiens)6480464[bisphenol A co-treated with Fulvestrant] results in increased methylation of TTC19 geneCTDPMID:31601247
Ttc19Ratcadmium atom increases expressionISOTTC19 (Homo sapiens)6480464Cadmium results in increased expression of TTC19 mRNACTDPMID:24376830
Ttc19Ratcadmium atom decreases expressionISOTTC19 (Homo sapiens)6480464Cadmium results in decreased expression of TTC19 mRNACTDPMID:23369406
Ttc19Ratcadmium dichloride decreases expressionISOTTC19 (Homo sapiens)6480464Cadmium Chloride results in decreased expression of TTC19 mRNACTDPMID:38568856
Ttc19Ratcarbon nanotube affects expressionISOTtc19 (Mus musculus)6480464Nanotubes more ...CTDPMID:25554681
Ttc19Ratcyclosporin A increases expressionISOTtc19 (Mus musculus)6480464Cyclosporine results in increased expression of TTC19 mRNACTDPMID:19770486
Ttc19Ratdiazinon increases methylationISOTTC19 (Homo sapiens)6480464Diazinon results in increased methylation of TTC19 geneCTDPMID:22964155
Ttc19Ratdibutyl phthalate increases expressionISOTtc19 (Mus musculus)6480464Dibutyl Phthalate results in increased expression of TTC19 mRNACTDPMID:21266533

1 to 20 of 47 rows

Biological Process

  
Object Symbol
Species
Term
Qualifier
Evidence
With
Reference
Notes
Source
Original Reference(s)
Ttc19Ratcell division involved_inIEAUniProtKB-KW:KW-01321600115GO_REF:0000043UniProtGO_REF:0000043
Ttc19Ratmitochondrial respiratory chain complex III assembly involved_inISOTTC19 (Homo sapiens)1624291 PMID:21278747RGDPMID:21278747
Ttc19Ratmitochondrial respiratory chain complex III assembly involved_inIBAFB:FBgn0032744 more ...1600115GO_REF:0000033GO_CentralGO_REF:0000033
Ttc19Ratmitochondrial respiratory chain complex III assembly involved_inIEAInterPro:IPR0403951600115GO_REF:0000002InterProGO_REF:0000002
Ttc19Ratmitochondrial respiratory chain complex III assembly involved_inISSUniProtKB:Q6DKK21600115GO_REF:0000024UniProtGO_REF:0000024

Cellular Component
1 to 9 of 9 rows

  
Object Symbol
Species
Term
Qualifier
Evidence
With
Reference
Notes
Source
Original Reference(s)
Ttc19Ratmembrane located_inIEAUniProtKB-KW:KW-04721600115GO_REF:0000043UniProtGO_REF:0000043
Ttc19Ratmitochondrial inner membrane located_inISSUniProtKB:Q6DKK21600115GO_REF:0000024UniProtGO_REF:0000024
Ttc19Ratmitochondrial inner membrane located_inIEAUniProtKB-KW:KW-09991600115GO_REF:0000043UniProtGO_REF:0000043
Ttc19Ratmitochondrial inner membrane located_inIEAUniProtKB-SubCell:SL-01681600115GO_REF:0000044UniProtGO_REF:0000044
Ttc19Ratmitochondrial inner membrane is_active_inIBAPANTHER:PTN000321934 and UniProtKB:Q6DKK21600115GO_REF:0000033GO_CentralGO_REF:0000033
Ttc19Ratmitochondrial inner membrane located_inISOTTC19 (Homo sapiens)1624291 PMID:21278747RGDPMID:21278747
Ttc19Ratmitochondrion located_inISOTTC19 (Homo sapiens)1624291 RGDGO_REF:0000052
Ttc19Ratmitochondrion located_inIEAUniProtKB-SubCell:SL-01731600115GO_REF:0000044UniProtGO_REF:0000044
Ttc19Ratmitochondrion located_inIEAUniProtKB-KW:KW-04961600115GO_REF:0000043UniProtGO_REF:0000043
1 to 9 of 9 rows

Molecular Function

  


#
Reference Title
Reference Citation
1. Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium. Gaudet P, etal., Brief Bioinform. 2011 Sep;12(5):449-62. doi: 10.1093/bib/bbr042. Epub 2011 Aug 27.
2. OMIM Disease Annotation Pipeline OMIM Disease Annotation Pipeline
3. ClinVar Automated Import and Annotation Pipeline RGD automated import pipeline for ClinVar variants, variant-to-disease annotations and gene-to-disease annotations
4. Data Import for Chemical-Gene Interactions RGD automated import pipeline for gene-chemical interactions
PMID:18614015   PMID:21278747  



Ttc19
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr81047,469,043 - 47,496,923 (+)NCBIGRCr8
mRatBN7.21046,969,723 - 46,997,607 (+)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl1046,969,727 - 46,997,789 (+)EnsemblmRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx1051,673,517 - 51,701,553 (+)NCBIRnor_SHRUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.01051,164,067 - 51,192,104 (+)NCBIRnor_SHRSPUTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.01046,667,475 - 46,695,511 (+)NCBIRnor_WKYUTH_Rnor_WKY_Bbb_1.0
Rnor_6.01048,599,321 - 48,627,374 (+)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl1048,599,321 - 48,627,374 (+)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.01048,387,826 - 48,415,743 (+)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.41048,450,922 - 48,479,028 (+)NCBIRGSC3.4RGSC_v3.4rn4RGSC3.4
Celera1046,215,636 - 46,243,767 (+)NCBICelera
Cytogenetic Map10q23NCBI
TTC19
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh381715,999,824 - 16,045,015 (+)NCBIGRCh38GRCh38hg38GRCh38
GRCh38.p14 Ensembl1715,999,784 - 16,045,015 (+)EnsemblGRCh38hg38GRCh38
GRCh371715,903,138 - 15,932,718 (+)NCBIGRCh37GRCh37hg19GRCh37
Build 361715,843,507 - 15,872,821 (+)NCBINCBI36Build 36hg18NCBI36
Build 341715,843,506 - 15,872,821NCBI
Celera1715,805,789 - 15,835,101 (+)NCBICelera
Cytogenetic Map17p12NCBI
HuRef1715,769,742 - 15,799,765 (+)NCBIHuRef
CHM1_11715,911,980 - 15,942,549 (+)NCBICHM1_1
T2T-CHM13v2.01715,902,040 - 15,947,641 (+)NCBIT2T-CHM13v2.0
Ttc19
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm391162,172,256 - 62,208,611 (+)NCBIGRCm39GRCm39mm39
GRCm39 Ensembl1162,172,299 - 62,219,277 (+)EnsemblGRCm39 Ensembl
GRCm381162,281,429 - 62,331,879 (+)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl1162,281,473 - 62,328,451 (+)EnsemblGRCm38mm10GRCm38
MGSCv371162,094,975 - 62,129,943 (+)NCBIGRCm37MGSCv37mm9NCBIm37
MGSCv361162,097,675 - 62,131,443 (+)NCBIMGSCv36mm8
Celera1169,200,414 - 69,235,362 (+)NCBICelera
Cytogenetic Map11B2NCBI
cM Map1138.02NCBI
Ttc19
(Chinchilla lanigera - long-tailed chinchilla)
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0 EnsemblNW_0049554671,381,625 - 1,405,014 (+)EnsemblChiLan1.0
ChiLan1.0NW_0049554671,381,105 - 1,405,509 (+)NCBIChiLan1.0ChiLan1.0
TTC19
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
NHGRI_mPanPan1-v21956,608,966 - 56,638,593 (-)NCBINHGRI_mPanPan1-v2
NHGRI_mPanPan11761,420,588 - 61,449,830 (-)NCBINHGRI_mPanPan1
Mhudiblu_PPA_v01734,902,211 - 34,931,963 (+)NCBIMhudiblu_PPA_v0Mhudiblu_PPA_v0panPan3
TTC19
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.1539,825,526 - 39,868,002 (-)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
CanFam3.1 Ensembl539,839,889 - 39,908,515 (-)EnsemblCanFam3.1canFam3CanFam3.1
Dog10K_Boxer_Tasha539,985,469 - 40,014,326 (-)NCBIDog10K_Boxer_Tasha
ROS_Cfam_1.0539,948,928 - 39,977,795 (-)NCBIROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl539,948,932 - 40,018,382 (-)EnsemblROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.1539,921,180 - 39,950,035 (-)NCBIUMICH_Zoey_3.1
UNSW_CanFamBas_1.0539,866,440 - 39,895,303 (-)NCBIUNSW_CanFamBas_1.0
UU_Cfam_GSD_1.0540,057,720 - 40,086,571 (-)NCBIUU_Cfam_GSD_1.0
Ttc19
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HiC_Itri_2NW_02440560259,245,246 - 59,288,687 (+)NCBIHiC_Itri_2
SpeTri2.0 EnsemblNW_004936821540,155 - 567,258 (-)EnsemblSpeTri2.0SpeTri2.0 Ensembl
SpeTri2.0NW_004936821524,183 - 566,953 (-)NCBISpeTri2.0SpeTri2.0SpeTri2.0
TTC19
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 Ensembl1259,393,224 - 59,418,995 (-)EnsemblSscrofa11.1susScr11Sscrofa11.1
Sscrofa11.11259,393,217 - 59,418,821 (-)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
Sscrofa10.21262,477,277 - 62,493,181 (+)NCBISscrofa10.2Sscrofa10.2susScr3
TTC19
(Chlorocebus sabaeus - green monkey)
Green Monkey AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.11615,632,017 - 15,662,857 (-)NCBIChlSab1.1ChlSab1.1chlSab2
Vero_WHO_p1.0NW_0236660595,298,505 - 5,328,623 (+)NCBIVero_WHO_p1.0Vero_WHO_p1.0
Ttc19
(Heterocephalus glaber - naked mole-rat)
Naked Mole-Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla_female_1.0 EnsemblNW_0046248774,381,368 - 4,404,083 (-)EnsemblHetGla_female_1.0HetGla_female_1.0 EnsemblhetGla2
HetGla 1.0NW_0046248774,380,164 - 4,404,104 (-)NCBIHetGla_female_1.0HetGla 1.0hetGla2

.

.
Variants in Ttc19
176 total Variants

Predicted Target Of
Summary Value
Count of predictions:155
Count of miRNA genes:110
Interacting mature miRNAs:135
Transcripts:ENSRNOT00000057777
Prediction methods:Miranda, Rnahybrid, Targetscan
Result types:miRGate_prediction

The detailed report is available here: Full Report CSV TAB Printer

miRNA Target Status data imported from miRGate (http://mirgate.bioinfo.cnio.es/).
For more information about miRGate, see PMID:25858286 or access the full paper here.


1 to 10 of 67 rows
The following QTLs overlap with this region.    Full Report CSV TAB Printer Gviewer
RGD ID
Symbol
Name
LOD
P Value
Trait
Sub Trait
Chr
Start
Stop
Species
61441Btemp1Thermal response to stress QTL 14body temperature trait (VT:0005535)core body temperature (CMO:0001036)103539245763642539Rat
9589136Insul27Insulin level QTL 2710.460.001blood insulin amount (VT:0001560)plasma insulin level (CMO:0000342)101147401056474010Rat
152025229Scl83Serum cholesterol level QTL 834.33blood cholesterol amount (VT:0000180)103571058068663659Rat
1578779Tcas10Tongue tumor susceptibility QTL 103.12tongue integrity trait (VT:0010553)number of squamous cell tumors of the tongue with diameter greater than 3 mm (CMO:0001950)103129743976297439Rat
152025227Bw195Body weight QTL 1955.73body mass (VT:0001259)104698969968663659Rat
631564Apr3Acute phase response QTL 33.9blood interleukin-6 amount (VT:0008595)plasma interleukin-6 level (CMO:0001927)101527595560275955Rat
1298069Bp168Blood pressure QTL 1685.5blood pressure trait (VT:0000183)systolic blood pressure (CMO:0000004)102652195798003205Rat
631552Vetf2Vascular elastic tissue fragility QTL 24.50.0002aorta elastic tissue integrity trait (VT:0010556)artery internal elastic lamina non-tumorous lesion count (CMO:0001913)104114263386142633Rat
631554Bp133Blood pressure QTL 1330.005arterial blood pressure trait (VT:2000000)systolic blood pressure (CMO:0000004)1074336463851208Rat
631557Bp136Blood pressure QTL 1360.003arterial blood pressure trait (VT:2000000)systolic blood pressure (CMO:0000004)103063205375632053Rat

1 to 10 of 67 rows
RH130301  
Rat AssemblyChrPosition (strand)SourceJBrowse
mRatBN7.21046,971,895 - 46,972,107 (+)MAPPERmRatBN7.2
Rnor_6.01048,601,490 - 48,601,701NCBIRnor6.0
Rnor_5.01048,389,995 - 48,390,206UniSTSRnor5.0
RGSC_v3.41048,453,091 - 48,453,302UniSTSRGSC3.4
Celera1046,217,805 - 46,218,016UniSTS
RH 3.4 Map10540.5UniSTS
Cytogenetic Map10q23UniSTS
AI227962  
Rat AssemblyChrPosition (strand)SourceJBrowse
mRatBN7.21046,997,397 - 46,997,571 (+)MAPPERmRatBN7.2
Rnor_6.01048,626,983 - 48,627,156NCBIRnor6.0
Rnor_5.01048,415,352 - 48,415,525UniSTSRnor5.0
RGSC_v3.41048,478,637 - 48,478,810UniSTSRGSC3.4
Celera1046,243,376 - 46,243,549UniSTS
RH 3.4 Map10545.3UniSTS
Cytogenetic Map10q23UniSTS




alimentary part of gastrointestinal system
appendage
circulatory system
ectoderm
endocrine system
endoderm
exocrine system
hemolymphoid system
hepatobiliary system
integumental system
mesenchyme
mesoderm
nervous system
renal system
reproductive system
respiratory system
9 11 49 113 91 90 59 25 59 6 218 97 93 45 60 31



Ensembl Acc Id: ENSRNOT00000057777   ⟹   ENSRNOP00000054591
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.2 Ensembl1046,969,727 - 46,997,789 (+)Ensembl
Rnor_6.0 Ensembl1048,599,321 - 48,627,374 (+)Ensembl
Ensembl Acc Id: ENSRNOT00000112760   ⟹   ENSRNOP00000083047
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.2 Ensembl1046,969,727 - 46,997,789 (+)Ensembl
Ensembl Acc Id: ENSRNOT00000118989   ⟹   ENSRNOP00000091692
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.2 Ensembl1046,969,727 - 46,997,789 (+)Ensembl
RefSeq Acc Id: NM_001109644   ⟹   NP_001103114
RefSeq Status: VALIDATED
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr81047,469,043 - 47,496,923 (+)NCBI
mRatBN7.21046,969,723 - 46,997,607 (+)NCBI
Rnor_6.01048,599,321 - 48,627,374 (+)NCBI
Rnor_5.01048,387,826 - 48,415,743 (+)NCBI
RGSC_v3.41048,450,922 - 48,479,028 (+)RGD
Celera1046,215,636 - 46,243,767 (+)RGD
Sequence:
RefSeq Acc Id: NM_001415772   ⟹   NP_001402701
RefSeq Status: VALIDATED
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr81047,469,043 - 47,496,923 (+)NCBI
mRatBN7.21046,969,723 - 46,997,607 (+)NCBI
RefSeq Acc Id: XM_039086898   ⟹   XP_038942826
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr81047,469,083 - 47,491,603 (+)NCBI
mRatBN7.21046,969,729 - 46,988,865 (+)NCBI
RefSeq Acc Id: XM_039086899   ⟹   XP_038942827
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr81047,469,083 - 47,491,603 (+)NCBI
mRatBN7.21046,969,729 - 46,988,865 (+)NCBI
RefSeq Acc Id: XM_063269901   ⟹   XP_063125971
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr81047,469,083 - 47,493,521 (+)NCBI
RefSeq Acc Id: NP_001103114   ⟸   NM_001109644
- Peptide Label: isoform 2
- UniProtKB: A0A8I6ACK4 (UniProtKB/TrEMBL)
- Sequence:
Ensembl Acc Id: ENSRNOP00000054591   ⟸   ENSRNOT00000057777
RefSeq Acc Id: XP_038942826   ⟸   XM_039086898
- Peptide Label: isoform X2
RefSeq Acc Id: XP_038942827   ⟸   XM_039086899
- Peptide Label: isoform X3
Ensembl Acc Id: ENSRNOP00000083047   ⟸   ENSRNOT00000112760

Name Modeler Protein Id AA Range Protein Structure
AF-D4A6D7-F1-model_v2 AlphaFold D4A6D7 1-365 view protein structure


eQTL   View at Phenogen
WGCNA   View at Phenogen
Tissue/Strain Expression   View at Phenogen

RGD ID:13697271
Promoter ID:EPDNEW_R7796
Type:initiation region
Name:Ttc19_1
Description:tetratricopeptide repeat domain 19
SO ACC ID:SO:0000170
Source:EPDNEW (Eukaryotic Promoter Database, http://epd.vital-it.ch/)
Experiment Methods:Single-end sequencing.
Position:
Rat AssemblyChrPosition (strand)Source
Rnor_6.01048,599,317 - 48,599,377EPDNEW


1 to 25 of 25 rows
Database
Acc Id
Source(s)
BioCyc Gene G2FUF-24777 BioCyc
Ensembl Genes ENSRNOG00000002977 Ensembl, ENTREZGENE, UniProtKB/Swiss-Prot
Ensembl Transcript ENSRNOT00000057777 ENTREZGENE
  ENSRNOT00000057777.3 UniProtKB/Swiss-Prot
  ENSRNOT00000112760 ENTREZGENE
  ENSRNOT00000112760.1 UniProtKB/Swiss-Prot
Gene3D-CATH 1.25.40.10 UniProtKB/Swiss-Prot
InterPro TPR-like_helical_dom_sf UniProtKB/Swiss-Prot
  TPR_repeat UniProtKB/Swiss-Prot
  TTC19 UniProtKB/Swiss-Prot
KEGG Report rno:691506 UniProtKB/Swiss-Prot
NCBI Gene 691506 ENTREZGENE
PANTHER PTHR13143 UniProtKB/Swiss-Prot
  TETRATRICOPEPTIDE REPEAT PROTEIN 19, MITOCHONDRIAL UniProtKB/Swiss-Prot
Pfam TPR_10 UniProtKB/Swiss-Prot
  TPR_12 UniProtKB/Swiss-Prot
PhenoGen Ttc19 PhenoGen
PROSITE TPR_REGION UniProtKB/Swiss-Prot
RatGTEx ENSRNOG00000002977 RatGTEx
SMART TPR UniProtKB/Swiss-Prot
Superfamily-SCOP SSF48452 UniProtKB/Swiss-Prot
UniProt A0A8I6ACK4 ENTREZGENE, UniProtKB/TrEMBL
  D4A3Z0 ENTREZGENE
  D4A6D7 ENTREZGENE, UniProtKB/Swiss-Prot
UniProt Secondary D4A3Z0 UniProtKB/Swiss-Prot
1 to 25 of 25 rows


Date Current Symbol Current Name Previous Symbol Previous Name Description Reference Status
2009-06-15 Ttc19  tetratricopeptide repeat domain 19  RGD1311797  similar to RIKEN cDNA 2810460C24   Data merged from RGD:1311797 1643240 APPROVED
2008-07-08 Ttc19  tetratricopeptide repeat domain 19  LOC687312  similar to Tetratricopeptide repeat protein 19 (TPR repeat protein 19)  Data merged from RGD:1586585 1643240 APPROVED
2008-04-30 RGD1311797  similar to RIKEN cDNA 2810460C24   RGD1311797_predicted  similar to RIKEN cDNA 2810460C24 (predicted)  'predicted' is removed 2292626 APPROVED
2008-03-06 Ttc19  tetratricopeptide repeat domain 19  LOC691506  similar to Tetratricopeptide repeat protein 19 (TPR repeat protein 19)  Nomenclature updated to reflect human and mouse nomenclature 1299863 APPROVED
2006-11-19 LOC691506  similar to Tetratricopeptide repeat protein 19 (TPR repeat protein 19)      Symbol and Name status set to provisional 70820 PROVISIONAL
2006-11-19 LOC687312  similar to Tetratricopeptide repeat protein 19 (TPR repeat protein 19)      Symbol and Name status set to provisional 70820 PROVISIONAL
2005-01-20 RGD1311797_predicted  similar to RIKEN cDNA 2810460C24 (predicted)  LOC287389_predicted    Symbol and Name status set to approved 1331353 APPROVED
2005-01-12 LOC287389_predicted  similar to RIKEN cDNA 2810460C24 (predicted)      Symbol and Name status set to provisional 70820 PROVISIONAL