Anxa6 (annexin A6) - Rat Genome Database

Name: Anxa6
Creator: Rat Genome Database
License: Creative Commons CC BY 4.0
Keywords: Rat Gene RGD Genome

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Gene: Anxa6 (annexin A6) Rattus norvegicus

Analyze

Symbol:

Anxa6

Name:

annexin A6

RGD ID:

621172

Description:

Enables calcium-dependent phospholipid binding activity. Predicted to be involved in several processes, including growth plate cartilage chondrocyte differentiation; mitochondrial calcium ion homeostasis; and plasma membrane repair. Predicted to act upstream of or within calcium ion transport. Located in apical plasma membrane; intercalated disc; and sarcolemma. Part of protein-containing complex. Orthologous to human ANXA6 (annexin A6); INTERACTS WITH (+)-schisandrin B; 2,3,7,8-tetrachlorodibenzodioxine; 2,4-dinitrotoluene.

Type:

protein-coding

RefSeq Status:

VALIDATED

Previously known as:

67 kDa calelectrin; annexin VI; annexin-6; Anx6; calcium-binding protein 65/67; calcium-binding protein CATA 65/67; calphobindin-II; CBP 65/67; chromobindin-20; CPB-II; lipocortin VI

RGD Orthologs

Alliance Genes

More Info

more info ...

More Info

Species	Gene symbol and name	Data Source	Assertion derived from	less info ...
Orthologs ¹				less info ...
Homo sapiens (human):	ANXA6 (annexin A6)	HGNC	EggNOG, Ensembl, HomoloGene, Inparanoid, NCBI, OMA, OrthoDB, OrthoMCL, Panther
Mus musculus (house mouse):	Anxa6 (annexin A6)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Chinchilla lanigera (long-tailed chinchilla):	Anxa6 (annexin A6)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Pan paniscus (bonobo/pygmy chimpanzee):	ANXA6 (annexin A6)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Canis lupus familiaris (dog):	ANXA6 (annexin A6)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Ictidomys tridecemlineatus (thirteen-lined ground squirrel):	Anxa6 (annexin A6)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Sus scrofa (pig):	ANXA6 (annexin A6)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Chlorocebus sabaeus (green monkey):	ANXA6 (annexin A6)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Heterocephalus glaber (naked mole-rat):	Anxa6 (annexin A6)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Alliance orthologs ³
Homo sapiens (human):	ANXA6 (annexin A6)	Alliance	DIOPT (Ensembl Compara\|HGNC\|Hieranoid\|InParanoid\|OMA\|OrthoFinder\|OrthoInspector\|PANTHER\|PhylomeDB\|SonicParanoid)
Mus musculus (house mouse):	Anxa6 (annexin A6)	Alliance	DIOPT (Ensembl Compara\|Hieranoid\|InParanoid\|OMA\|OrthoFinder\|OrthoInspector\|PANTHER\|PhylomeDB\|SonicParanoid)
Danio rerio (zebrafish):	anxa6 (annexin A6)	Alliance	DIOPT (Ensembl Compara\|Hieranoid\|InParanoid\|OMA\|OrthoFinder\|OrthoInspector\|PANTHER\|PhylomeDB\|SonicParanoid)
Drosophila melanogaster (fruit fly):	AnxB10	Alliance	DIOPT (OrthoFinder\|PANTHER\|PhylomeDB)
Xenopus tropicalis (tropical clawed frog):	anxa6	Alliance	DIOPT (Ensembl Compara\|Hieranoid\|InParanoid\|OMA\|OrthoFinder\|OrthoInspector\|PANTHER\|PhylomeDB\|SonicParanoid)

Latest Assembly:

mRatBN7.2 - mRatBN7.2 Assembly

Position:

Rat Assembly	Chr	Position (strand)	Source	Genome Browsers
Rat Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
mRatBN7.2	10	39,101,395 - 39,156,483 (-)	NCBI	mRatBN7.2	mRatBN7.2
mRatBN7.2 Ensembl	10	39,097,109 - 39,156,433 (-)	Ensembl		mRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx	10	43,789,578 - 43,844,689 (-)	NCBI	Rnor_SHR	UTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.0	10	43,279,657 - 43,334,764 (-)	NCBI	Rnor_SHRSP	UTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.0	10	38,783,353 - 38,838,463 (-)	NCBI	Rnor_WKY	UTH_Rnor_WKY_Bbb_1.0
Rnor_6.0	10	40,320,581 - 40,375,605 (-)	NCBI	Rnor6.0	Rnor_6.0	rn6	Rnor6.0
Rnor_6.0 Ensembl	10	40,320,581 - 40,375,605 (-)	Ensembl	Rnor6.0		rn6	Rnor6.0
Rnor_5.0	10	40,092,956 - 40,148,308 (-)	NCBI	Rnor5.0	Rnor_5.0	rn5	Rnor5.0
RGSC_v3.4	10	40,383,975 - 40,439,683 (-)	NCBI	RGSC3.4	RGSC_v3.4	rn4	RGSC3.4
RGSC_v3.1	10	40,397,765 - 40,453,266 (-)	NCBI
Celera	10	38,439,076 - 38,494,023 (-)	NCBI		Celera
Cytogenetic Map	10	q22	NCBI

JBrowse:

View Region in Genome Browser (JBrowse)

Model

Annotation Click to see Annotation Detail View

Disease Annotations Click to see Annotation Detail View

acute myeloid leukemia (ISO)

Chemical and Drug Induced Liver Injury (ISO)

familial adenomatous polyposis 1 (ISO)

genetic disease (ISO)

hepatocellular carcinoma (ISO)

Hereditary Neoplastic Syndromes (ISO)

Gene-Chemical Interaction Annotations Click to see Annotation Detail View

(+)-schisandrin B (EXP)

(1->4)-beta-D-glucan (ISO)

1,2-dimethylhydrazine (ISO)

17alpha-ethynylestradiol (ISO)

17beta-estradiol (ISO)

2,3,7,8-tetrachlorodibenzodioxine (EXP,ISO)

2,4-dinitrotoluene (EXP)

2,6-dinitrotoluene (EXP)

2-amino-14,16-dimethyloctadecan-3-ol (ISO)

3-isobutyl-1-methyl-7H-xanthine (ISO)

4,4'-diaminodiphenylmethane (ISO)

4,4'-sulfonyldiphenol (ISO)

4-hydroxyphenyl retinamide (ISO)

5-aza-2'-deoxycytidine (ISO)

6-propyl-2-thiouracil (EXP)

aflatoxin B1 (ISO)

all-trans-retinoic acid (ISO)

allethrin (EXP)

ammonium chloride (EXP)

arsenite(3-) (ISO)

benzatropine (ISO)

benzo[a]pyrene (ISO)

bisphenol A (EXP,ISO)

Bisphenol B (ISO)

bisphenol F (ISO)

bleomycin A2 (EXP)

butanal (ISO)

C60 fullerene (EXP)

carbon nanotube (ISO)

chloroprene (ISO)

cisplatin (ISO)

clozapine (ISO)

copper atom (ISO)

copper(0) (ISO)

copper(II) sulfate (ISO)

cyclosporin A (ISO)

cyhalothrin (EXP)

cylindrospermopsin (ISO)

cypermethrin (EXP)

cytarabine (ISO)

dexamethasone (ISO)

diuron (EXP,ISO)

dorsomorphin (ISO)

doxorubicin (ISO)

endosulfan (EXP)

fenthion (ISO)

fenvalerate (EXP)

flavonoids (EXP)

genistein (ISO)

gentamycin (EXP)

griseofulvin (ISO)

heparin (EXP)

indometacin (ISO)

inulin (ISO)

irinotecan (ISO)

isoflavones (EXP)

ivermectin (ISO)

leflunomide (EXP)

lidocaine (EXP)

methidathion (ISO)

methyl methanesulfonate (ISO)

methylmercury chloride (ISO)

morphine (EXP)

N-methyl-4-phenylpyridinium (ISO)

N-methylformamide (ISO)

N-nitrosomorpholine (EXP)

ozone (ISO)

paracetamol (ISO)

pentanal (ISO)

perfluorooctane-1-sulfonic acid (ISO)

phenobarbital (ISO)

propanal (ISO)

propiconazole (ISO)

pyrethrins (EXP)

quercetin (ISO)

resveratrol (ISO)

rotenone (EXP)

SB 431542 (ISO)

silicon dioxide (ISO)

sodium arsenite (ISO)

sodium dichromate (EXP)

sodium fluoride (ISO)

sunitinib (ISO)

tetrachloromethane (EXP,ISO)

thioacetamide (EXP)

trichloroethene (EXP)

tunicamycin (ISO)

urethane (ISO)

valproic acid (ISO)

vinclozolin (EXP)

vitamin E (ISO)

vorinostat (ISO)

Gene Ontology Annotations Click to see Annotation Detail View

Biological Process

apoptotic signaling pathway (IBA,IEA,ISO)

calcium ion transmembrane transport (IEA)

calcium ion transport (IEA,ISO)

growth plate cartilage chondrocyte differentiation (IBA)

mitochondrial calcium ion homeostasis (IBA,IEA,ISO)

monoatomic ion transmembrane transport (ISO)

negative regulation of sequestering of calcium ion (IBA)

neural crest cell migration (IBA)

plasma membrane repair (IBA)

regulation of muscle contraction (IBA,IEA,ISO)

secretion (TAS)

Cellular Component

apical plasma membrane (IDA)

cytoplasm (IBA)

focal adhesion (IBA)

intercalated disc (IDA)

late endosome membrane (ISO)

lysosomal membrane (ISO)

melanosome (IEA)

membrane (IDA)

mitochondrion (IEA)

perinuclear region of cytoplasm (IEA,ISO)

protein-containing complex (IDA)

sarcolemma (IBA,IDA)

Molecular Function

actin filament binding (IBA)

calcium channel activity (IBA)

calcium ion binding (IBA,IEA)

calcium-dependent phospholipid binding (IBA,IDA,IEA,ISO,TAS)

calcium-dependent protein binding (ISO)

cholesterol binding (IBA,ISO)

chondroitin sulfate binding (IBA)

GTP binding (IBA,ISO)

identical protein binding (ISO)

ligand-gated monoatomic ion channel activity (IBA,ISO)

lipid binding (ISO)

phosphatidylserine binding (IBA)

protein binding (IPI,ISO)

protein-containing complex binding (IPI)

References

References - curated

#	Reference Title	Reference Citation
1.	Dentin phosphoprotein binds annexin 2 and is involved in calcium transport in rat kidney ureteric bud cells.	Alvares K, etal., J Biol Chem. 2013 May 3;288(18):13036-45. doi: 10.1074/jbc.M112.389627. Epub 2013 Mar 22.
2.	Significant Down-Regulation of Urea Cycle Generates Clinically Relevant Proteomic Signature in Hepatocellular Carcinoma Patients with Macrovascular Invasion.	Cao Y, etal., J Proteome Res. 2019 May 3;18(5):2032-2044. doi: 10.1021/acs.jproteome.8b00921. Epub 2019 Mar 29.
3.	Identification of a novel protein complex containing annexin VI, Fyn, Pyk2, and the p120(GAP) C2 domain.	Chow A, etal., FEBS Lett. 2000 Mar 3;469(1):88-92.
4.	Identification and immunolocalisation of annexins V and VI, the major cardiac annexins, in rat heart.	Doubell AF, etal., Cardiovasc Res. 1993 Jul;27(7):1359-67.
5.	Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium.	Gaudet P, etal., Brief Bioinform. 2011 Sep;12(5):449-62. doi: 10.1093/bib/bbr042. Epub 2011 Aug 27.
6.	Rat ISS GO annotations from GOA human gene data--August 2006	GOA data from the GO Consortium
7.	Rat ISS GO annotations from MGI mouse gene data--August 2006	MGD data from the GO Consortium
8.	Electronic Transfer of LocusLink and RefSeq Data	NCBI rat LocusLink and RefSeq merged data July 26, 2002
9.	Identification of a multiprotein "motor" complex binding to water channel aquaporin-2.	Noda Y, etal., Biochem Biophys Res Commun. 2005 May 20;330(4):1041-7.
10.	GOA pipeline	RGD automated data pipeline
11.	Data Import for Chemical-Gene Interactions	RGD automated import pipeline for gene-chemical interactions
12.	Identification of annexin VI as a Ca2+-sensitive CRHSP-28-binding protein in pancreatic acinar cells.	Thomas DD, etal., J Biol Chem 2002 Sep 20;277(38):35496-502.

Additional References at PubMed

PMID:1618851	PMID:2138016	PMID:7607247	PMID:11919174	PMID:12477932	PMID:15078881	PMID:15226301	PMID:16605264	PMID:19056867	PMID:19946888	PMID:20387083	PMID:20458337
PMID:20506562	PMID:21272378	PMID:21362503	PMID:21423176	PMID:22871113	PMID:23341998	PMID:23360953	PMID:23376485	PMID:23533145	PMID:24403064	PMID:28369848

Genomics

Comparative Map Data

Anxa6
(Rattus norvegicus - Norway rat)

Rat Assembly	Chr	Position (strand)	Source	Genome Browsers
Rat Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
mRatBN7.2	10	39,101,395 - 39,156,483 (-)	NCBI	mRatBN7.2	mRatBN7.2
mRatBN7.2 Ensembl	10	39,097,109 - 39,156,433 (-)	Ensembl		mRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx	10	43,789,578 - 43,844,689 (-)	NCBI	Rnor_SHR	UTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.0	10	43,279,657 - 43,334,764 (-)	NCBI	Rnor_SHRSP	UTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.0	10	38,783,353 - 38,838,463 (-)	NCBI	Rnor_WKY	UTH_Rnor_WKY_Bbb_1.0
Rnor_6.0	10	40,320,581 - 40,375,605 (-)	NCBI	Rnor6.0	Rnor_6.0	rn6	Rnor6.0
Rnor_6.0 Ensembl	10	40,320,581 - 40,375,605 (-)	Ensembl	Rnor6.0		rn6	Rnor6.0
Rnor_5.0	10	40,092,956 - 40,148,308 (-)	NCBI	Rnor5.0	Rnor_5.0	rn5	Rnor5.0
RGSC_v3.4	10	40,383,975 - 40,439,683 (-)	NCBI	RGSC3.4	RGSC_v3.4	rn4	RGSC3.4
RGSC_v3.1	10	40,397,765 - 40,453,266 (-)	NCBI
Celera	10	38,439,076 - 38,494,023 (-)	NCBI		Celera
Cytogenetic Map	10	q22	NCBI

ANXA6
(Homo sapiens - human)

Human Assembly	Chr	Position (strand)	Source	Genome Browsers
Human Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
GRCh38	5	151,100,706 - 151,157,779 (-)	NCBI	GRCh38	GRCh38	hg38	GRCh38
GRCh38.p14 Ensembl	5	151,100,706 - 151,157,815 (-)	Ensembl	GRCh38		hg38	GRCh38
GRCh37	5	150,480,267 - 150,537,340 (-)	NCBI	GRCh37	GRCh37	hg19	GRCh37
Build 36	5	150,460,461 - 150,517,560 (-)	NCBI	NCBI36	Build 36	hg18	NCBI36
Build 34	5	150,460,862 - 150,517,585	NCBI
Celera	5	146,561,624 - 146,618,767 (-)	NCBI		Celera
Cytogenetic Map	5	q33.1	NCBI
HuRef	5	145,626,078 - 145,683,049 (-)	NCBI		HuRef
CHM1_1	5	149,913,062 - 149,970,211 (-)	NCBI		CHM1_1
T2T-CHM13v2.0	5	151,637,192 - 151,694,982 (-)	NCBI		T2T-CHM13v2.0

Anxa6
(Mus musculus - house mouse)

Mouse Assembly	Chr	Position (strand)	Source	Genome Browsers
Mouse Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
GRCm39	11	54,869,779 - 54,924,297 (-)	NCBI	GRCm39	GRCm39	mm39
GRCm39 Ensembl	11	54,869,934 - 54,924,271 (-)	Ensembl		GRCm39 Ensembl
GRCm38	11	54,978,953 - 55,033,471 (-)	NCBI	GRCm38	GRCm38	mm10	GRCm38
GRCm38.p6 Ensembl	11	54,979,108 - 55,033,445 (-)	Ensembl	GRCm38		mm10	GRCm38
MGSCv37	11	54,792,464 - 54,846,973 (-)	NCBI	GRCm37	MGSCv37	mm9	NCBIm37
MGSCv36	11	54,822,534 - 54,876,837 (-)	NCBI		MGSCv36	mm8
Celera	11	59,568,328 - 59,623,325 (-)	NCBI		Celera
Cytogenetic Map	11	B1.3	NCBI
cM Map	11	32.13	NCBI

Anxa6
(Chinchilla lanigera - long-tailed chinchilla)

Chinchilla Assembly	Chr	Position (strand)	Source	Genome Browsers
Chinchilla Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
ChiLan1.0 Ensembl	NW_004955408	2,522,027 - 2,570,426 (+)	Ensembl	ChiLan1.0
ChiLan1.0	NW_004955408	2,522,027 - 2,565,862 (+)	NCBI	ChiLan1.0	ChiLan1.0

ANXA6
(Pan paniscus - bonobo/pygmy chimpanzee)

Bonobo Assembly	Chr	Position (strand)	Source	Genome Browsers
Bonobo Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
NHGRI_mPanPan1	5	144,470,664 - 144,529,116 (-)	NCBI		NHGRI_mPanPan1
Mhudiblu_PPA_v0	5	146,528,446 - 146,585,186 (-)	NCBI	Mhudiblu_PPA_v0	Mhudiblu_PPA_v0	panPan3
PanPan1.1	5	152,530,545 - 152,587,152 (-)	NCBI	panpan1.1	PanPan1.1	panPan2
PanPan1.1 Ensembl	5	152,530,445 - 152,652,231 (-)	Ensembl	panpan1.1		panPan2

ANXA6
(Canis lupus familiaris - dog)

Dog Assembly	Chr	Position (strand)	Source	Genome Browsers
Dog Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
CanFam3.1	4	58,091,186 - 58,140,102 (+)	NCBI	CanFam3.1	CanFam3.1	canFam3	CanFam3.1
CanFam3.1 Ensembl	4	58,091,251 - 58,139,372 (+)	Ensembl	CanFam3.1		canFam3	CanFam3.1
ROS_Cfam_1.0	4	58,529,305 - 58,578,378 (+)	NCBI		ROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl	4	58,528,478 - 58,578,372 (+)	Ensembl		ROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.1	4	58,347,153 - 58,396,255 (+)	NCBI		UMICH_Zoey_3.1
UNSW_CanFamBas_1.0	4	58,445,645 - 58,494,709 (+)	NCBI		UNSW_CanFamBas_1.0
UU_Cfam_GSD_1.0	4	58,949,170 - 58,998,237 (+)	NCBI		UU_Cfam_GSD_1.0

Anxa6
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)

Squirrel Assembly	Chr	Position (strand)	Source	Genome Browsers
Squirrel Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
HiC_Itri_2	NW_024407213	116,975,286 - 117,026,700 (-)	NCBI		HiC_Itri_2
SpeTri2.0 Ensembl	NW_004936647	3,976,903 - 4,029,485 (-)	Ensembl	SpeTri2.0
SpeTri2.0	NW_004936647	3,978,047 - 4,029,485 (-)	NCBI	SpeTri2.0	SpeTri2.0		SpeTri2.0

ANXA6
(Sus scrofa - pig)

Pig Assembly	Chr	Position (strand)	Source	Genome Browsers
Pig Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
Sscrofa11.1 Ensembl	16	71,857,258 - 71,913,723 (+)	Ensembl	Sscrofa11.1		susScr11	Sscrofa11.1
Sscrofa11.1	16	71,857,229 - 71,913,723 (+)	NCBI	Sscrofa11.1	Sscrofa11.1	susScr11	Sscrofa11.1
Sscrofa10.2	16	78,135,702 - 78,147,081 (+)	NCBI	Sscrofa10.2	Sscrofa10.2	susScr3

ANXA6
(Chlorocebus sabaeus - green monkey)

Green Monkey Assembly	Chr	Position (strand)	Source	Genome Browsers
Green Monkey Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
ChlSab1.1	23	53,657,377 - 53,714,828 (-)	NCBI	ChlSab1.1	ChlSab1.1	chlSab2
ChlSab1.1 Ensembl	23	53,657,718 - 53,714,850 (-)	Ensembl	ChlSab1.1	ChlSab1.1 Ensembl	chlSab2
Vero_WHO_p1.0	NW_023666034	23,999,800 - 24,057,882 (+)	NCBI	Vero_WHO_p1.0	Vero_WHO_p1.0

Anxa6
(Heterocephalus glaber - naked mole-rat)

Naked Mole-Rat Assembly	Chr	Position (strand)	Source	Genome Browsers
Naked Mole-Rat Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
HetGla_female_1.0 Ensembl	NW_004624733	41,024,514 - 41,071,353 (-)	Ensembl	HetGla_female_1.0	HetGla_female_1.0 Ensembl	hetGla2
HetGla 1.0	NW_004624733	41,024,503 - 41,071,390 (-)	NCBI	HetGla_female_1.0	HetGla 1.0	hetGla2

Variants

Variants in Anxa6
240 total Variants

miRNA Target Status

Predicted Target Of

	Summary Value
Count of predictions:	65
Count of miRNA genes:	57
Interacting mature miRNAs:	61
Transcripts:	ENSRNOT00000014464
Prediction methods:	Miranda, Rnahybrid
Result types:	miRGate_prediction

The detailed report is available here: Full Report CSV TAB Printer

miRNA Target Status data imported from miRGate (http://mirgate.bioinfo.cnio.es/).
For more information about miRGate, see PMID:25858286 or access the full paper here.

QTLs in Region (mRatBN7.2)

The following QTLs overlap with this region.

RGD ID	Symbol	Name	LOD	P Value	Trait	Sub Trait	Chr	Start	Stop	Species
7411611	Foco17	Food consumption QTL 17	18.7	0.001	eating behavior trait (VT:0001431)	feed conversion ratio (CMO:0001312)	10	1	42315980	Rat
70223	Bp57	Blood pressure QTL 57	5		arterial blood pressure trait (VT:2000000)	systolic blood pressure (CMO:0000004)	10	1	80676123	Rat
10401803	Kidm50	Kidney mass QTL 50			kidney mass (VT:0002707)	both kidneys wet weight (CMO:0000085)	10	418344	45418344	Rat
631554	Bp133	Blood pressure QTL 133		0.005	arterial blood pressure trait (VT:2000000)	systolic blood pressure (CMO:0000004)	10	743364	63851208	Rat
2313064	Bmd71	Bone mineral density QTL 71	0.9	0.0001	tibia mineral mass (VT:1000283)	compact volumetric bone mineral density (CMO:0001730)	10	5387014	50387014	Rat
2313066	Bss63	Bone structure and strength QTL 63	1.4	0.0001	tibia strength trait (VT:1000284)	bone polar moment of inertia (CMO:0001558)	10	5387014	50387014	Rat
2313081	Bss64	Bone structure and strength QTL 64	1.3	0.0001	tibia strength trait (VT:1000284)	tibia total energy absorbed before break (CMO:0001736)	10	5387014	50387014	Rat
2313095	Bss62	Bone structure and strength QTL 62	1.5	0.0001	tibia size trait (VT:0100001)	tibia midshaft cross-sectional area (CMO:0001717)	10	5387014	50387014	Rat
2313104	Bss61	Bone structure and strength QTL 61	0.9	0.0001	tibia area (VT:1000281)	tibia midshaft cross-sectional area (CMO:0001717)	10	5387014	50387014	Rat
2298544	Neuinf9	Neuroinflammation QTL 9	4.6		nervous system integrity trait (VT:0010566)	spinal cord complement component 1, q subcomponent, B chain mRNA level (CMO:0002126)	10	5801990	62146030	Rat
8662860	Vetf10	Vascular elastic tissue fragility QTL 10			artery integrity trait (VT:0010639)	number of ruptures of the internal elastic lamina of the abdominal aorta and iliac arteries (CMO:0002562)	10	6154182	73453136	Rat
61427	Cia16	Collagen induced arthritis QTL 16	3.2		joint integrity trait (VT:0010548)	joint inflammation composite score (CMO:0000919)	10	6357896	96121100	Rat
1578761	Stresp21	Stress response QTL 21	3.3		thymus mass (VT:0004954)	thymus wet weight (CMO:0000855)	10	6375746	51375746	Rat
2303118	Mamtr7	Mammary tumor resistance QTL 7		0.003	mammary gland integrity trait (VT:0010552)	mammary tumor growth rate (CMO:0000344)	10	9658275	104670812	Rat
9590310	Scort19	Serum corticosterone level QTL 19	6.3	0.001	blood corticosterone amount (VT:0005345)	plasma corticosterone level (CMO:0001173)	10	11474010	56474010	Rat
9590268	Scort13	Serum corticosterone level QTL 13	3.26	0.001	blood corticosterone amount (VT:0005345)	plasma corticosterone level (CMO:0001173)	10	11474010	56474010	Rat
9589136	Insul27	Insulin level QTL 27	10.46	0.001	blood insulin amount (VT:0001560)	plasma insulin level (CMO:0000342)	10	11474010	56474010	Rat
2301967	Cm73	Cardiac mass QTL 73	4.55		heart left ventricle mass (VT:0007031)	heart left ventricle weight to body weight ratio (CMO:0000530)	10	14487011	89062041	Rat
631268	Cia21	Collagen induced arthritis QTL 21	3.1		joint integrity trait (VT:0010548)	joint inflammation composite score (CMO:0000919)	10	14487011	104060283	Rat
2316949	Gluco60	Glucose level QTL 60	3.7		blood glucose amount (VT:0000188)	blood glucose level (CMO:0000046)	10	14487011	107057807	Rat
1354587	Kidm21	Kidney mass QTL 21	3.3		kidney mass (VT:0002707)	right kidney wet weight (CMO:0000082)	10	15028513	60430477	Rat
631564	Apr3	Acute phase response QTL 3	3.9		blood interleukin-6 amount (VT:0008595)	plasma interleukin-6 level (CMO:0001927)	10	15275955	60275955	Rat
6893350	Bw99	Body weight QTL 99	0.87	0.16	body mass (VT:0001259)	body weight (CMO:0000012)	1	15906665	60906665	Rat
6893352	Bw100	Body weight QTL 100	0.33	0.6	body mass (VT:0001259)	body weight (CMO:0000012)	1	15906665	60906665	Rat
631532	Cm50	Cardiac mass QTL 50	6.6		heart mass (VT:0007028)	calculated heart weight (CMO:0000073)	10	17907113	51786432	Rat
1598852	Anxrr19	Anxiety related response QTL 19	5.07		body movement coordination trait (VT:0005424)	number of rearing movements in an experimental apparatus (CMO:0001752)	10	18167841	63167841	Rat
2313055	Bw96	Body weight QTL 96	3.6	0.0001	body mass (VT:0001259)	body weight (CMO:0000012)	10	19606483	64606483	Rat
2313087	Bmd80	Bone mineral density QTL 80	3.2	0.0001	tibia mineral mass (VT:1000283)	total volumetric bone mineral density (CMO:0001728)	10	19606483	64606483	Rat
1554317	Bmd4	Bone mineral density QTL 4	9.4	0.0001	lumbar vertebra mineral mass (VT:0010511)	volumetric bone mineral density (CMO:0001553)	10	19816042	99406971	Rat
1581497	Esta1	Estrogen-induced thymic atrophy QTL 1			thymus mass (VT:0004954)	thymus wet weight (CMO:0000855)	10	21329805	61345413	Rat
724556	Pur2	Proteinuria QTL 2	5.5		urine protein amount (VT:0005160)	urine protein level (CMO:0000591)	10	22427500	90627625	Rat
61354	Pia10	Pristane induced arthritis QTL 10		0.01	joint integrity trait (VT:0010548)	joint inflammation composite score (CMO:0000919)	10	23444813	104060283	Rat
631267	Cia20	Collagen induced arthritis QTL 20	3.2		joint integrity trait (VT:0010548)	joint inflammation composite score (CMO:0000919)	10	23444813	104060283	Rat
61325	Aia5	Adjuvant induced arthritis QTL 5		0.01	joint integrity trait (VT:0010548)	joint inflammation composite score (CMO:0000919)	10	23444813	104060283	Rat
70224	Eae3	Experimental allergic encephalomyelitis QTL 3	4.1		nervous system integrity trait (VT:0010566)	experimental autoimmune encephalomyelitis incidence/prevalence measurement (CMO:0001046)	10	26521957	61345413	Rat
1298069	Bp168	Blood pressure QTL 168	5.5		blood pressure trait (VT:0000183)	systolic blood pressure (CMO:0000004)	10	26521957	98003205	Rat
631542	Bp82	Blood pressure QTL 82	6.8		arterial blood pressure trait (VT:2000000)	systolic blood pressure (CMO:0000004)	10	26521957	98952741	Rat
2300171	Bmd58	Bone mineral density QTL 58	4.9	0.0001	lumbar vertebra mineral mass (VT:0010511)	volumetric bone mineral density (CMO:0001553)	10	26944628	71944628	Rat
10402859	Bp381	Blood pressure QTL 381		0.002	arterial blood pressure trait (VT:2000000)	mean arterial blood pressure (CMO:0000009)	10	27606468	72606468	Rat
2292441	Bp308	Blood pressure QTL 308			arterial blood pressure trait (VT:2000000)	mean arterial blood pressure (CMO:0000009)	10	27606468	72606468	Rat
724527	Bp148	Blood pressure QTL 148		0.0001	arterial blood pressure trait (VT:2000000)	mean arterial blood pressure (CMO:0000009)	10	28453136	73453136	Rat
1600371	Mcs21	Mammary carcinoma susceptibility QTL 21	3		mammary gland integrity trait (VT:0010552)	mammary tumor growth rate (CMO:0000344)	10	28875650	52200160	Rat
1331762	Rf40	Renal function QTL 40	3.873		kidney blood vessel physiology trait (VT:0100012)	absolute change in renal vascular resistance (CMO:0001900)	10	29299504	64155584	Rat
1331791	Cm31	Cardiac mass QTL 31	3.84606		heart mass (VT:0007028)	heart wet weight (CMO:0000069)	10	29299504	107211142	Rat
631557	Bp136	Blood pressure QTL 136		0.003	arterial blood pressure trait (VT:2000000)	systolic blood pressure (CMO:0000004)	10	30632053	75632053	Rat
1576311	Pia26	Pristane induced arthritis QTL 26			joint integrity trait (VT:0010548)	joint inflammation composite score (CMO:0000919)	10	31224026	75632053	Rat
1578779	Tcas10	Tongue tumor susceptibility QTL 10	3.12		tongue integrity trait (VT:0010553)	number of squamous cell tumors of the tongue with diameter greater than 3 mm (CMO:0001950)	10	31297439	76297439	Rat
1576319	Cia29	Collagen induced arthritis QTL 29			joint integrity trait (VT:0010548)	joint inflammation composite score (CMO:0000919)	10	33973921	78973921	Rat
61332	Eau3	Experimental allergic uveoretinitis QTL 3		0.004	uvea integrity trait (VT:0010551)	experimental autoimmune uveitis score (CMO:0001504)	10	34490559	45579777	Rat
1354614	Hpcl1	Hepatic cholesterol level QTL 1	3.3		liver cholesterol amount (VT:0010498)	liver cholesterol level (CMO:0001597)	10	35392267	51793994	Rat
1358897	Stresp6	Stress response QTL 6	4.17	0.022	blood norepinephrine amount (VT:0005663)	plasma norepinephrine level (CMO:0001010)	10	35392267	64155584	Rat
61441	Btemp1	Thermal response to stress QTL 1	4		body temperature trait (VT:0005535)	core body temperature (CMO:0001036)	10	35392457	63642539	Rat
2317042	Aia20	Adjuvant induced arthritis QTL 20	3.38		joint integrity trait (VT:0010548)	right rear ankle joint diameter (CMO:0002150)	10	37565079	82565079	Rat
2317043	Aia7	Adjuvant induced arthritis QTL 7	3.82		joint integrity trait (VT:0010548)	left rear ankle joint diameter (CMO:0002149)	10	37565079	82565079	Rat

Markers in Region

AW525206

Rat Assembly	Chr	Position (strand)	Source	JBrowse
mRatBN7.2	10	39,101,412 - 39,101,607 (+)	MAPPER	mRatBN7.2
Rnor_6.0	10	40,320,599 - 40,320,793	NCBI	Rnor6.0
Rnor_5.0	10	40,092,974 - 40,093,168	UniSTS	Rnor5.0
RGSC_v3.4	10	40,383,993 - 40,384,187	UniSTS	RGSC3.4
Celera	10	38,439,094 - 38,439,288	UniSTS
RH 3.4 Map	10	406.0	UniSTS
Cytogenetic Map	10	q22	UniSTS

RH136640

Rat Assembly	Chr	Position (strand)	Source	JBrowse
mRatBN7.2	10	39,114,255 - 39,114,462 (+)	MAPPER	mRatBN7.2
Rnor_6.0	10	40,333,439 - 40,333,645	NCBI	Rnor6.0
Rnor_5.0	10	40,106,123 - 40,106,329	UniSTS	Rnor5.0
RGSC_v3.4	10	40,397,518 - 40,397,724	UniSTS	RGSC3.4
Celera	10	38,451,848 - 38,452,054	UniSTS
RH 3.4 Map	10	411.4	UniSTS
Cytogenetic Map	10	q22	UniSTS

BE118744

Rat Assembly	Chr	Position (strand)	Source	JBrowse
mRatBN7.2	10	39,154,008 - 39,154,184 (+)	MAPPER	mRatBN7.2
Rnor_6.0	10	40,373,190 - 40,373,365	NCBI	Rnor6.0
Rnor_5.0	10	40,145,875 - 40,146,050	UniSTS	Rnor5.0
RGSC_v3.4	10	40,437,268 - 40,437,443	UniSTS	RGSC3.4
Celera	10	38,491,608 - 38,491,783	UniSTS
RH 3.4 Map	10	411.1	UniSTS
Cytogenetic Map	10	q22	UniSTS

Expression

RNA-SEQ Expression

High: > 1000 TPM value Medium: Between 11 and 1000 TPM
Low: Between 0.5 and 10 TPM Below Cutoff: < 0.5 TPM

	alimentary part of gastrointestinal system	circulatory system	endocrine system	exocrine system	hemolymphoid system	hepatobiliary system	integumental system	musculoskeletal system	nervous system	renal system	reproductive system	respiratory system	appendage
High
Medium	3	43	57	41	19	41	8	11	74	35	41	11	8
Low
Below cutoff

View RNA-SEQ Expression Data

Sequence

Nucleotide Sequences


RefSeq Transcripts	NM_024156	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	XM_006246340	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	XM_006246341	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	XM_017597542	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	XM_039086912	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
GenBank Nucleotide	AC093965	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	BC072523	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	CB585592	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	CH473948	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	FQ219262	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	JACYVU010000219	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles

RefSeq Acc Id:

ENSRNOT00000014464 ⟹ ENSRNOP00000014464

Type:

CODING

Position:

Rat Assembly	Chr	Position (strand)	Source
mRatBN7.2 Ensembl	10	39,101,398 - 39,156,420 (-)	Ensembl
Rnor_6.0 Ensembl	10	40,320,581 - 40,375,605 (-)	Ensembl

RefSeq Acc Id:

ENSRNOT00000096029 ⟹ ENSRNOP00000091681

Type:

CODING

Position:

Rat Assembly	Chr	Position (strand)	Source
mRatBN7.2 Ensembl	10	39,101,397 - 39,156,433 (-)	Ensembl

RefSeq Acc Id:

ENSRNOT00000106165 ⟹ ENSRNOP00000079087

Type:

CODING

Position:

Rat Assembly	Chr	Position (strand)	Source
mRatBN7.2 Ensembl	10	39,097,109 - 39,156,412 (-)	Ensembl

RefSeq Acc Id:

ENSRNOT00000111975 ⟹ ENSRNOP00000080378

Type:

CODING

Position:

Rat Assembly	Chr	Position (strand)	Source
mRatBN7.2 Ensembl	10	39,101,387 - 39,156,397 (-)	Ensembl

RefSeq Acc Id:

ENSRNOT00000119845 ⟹ ENSRNOP00000076795

Type:

CODING

Position:

Rat Assembly	Chr	Position (strand)	Source
mRatBN7.2 Ensembl	10	39,101,387 - 39,156,397 (-)	Ensembl

RefSeq Acc Id:

NM_024156 ⟹ NP_077070

RefSeq Status:

VALIDATED

Type:

CODING

Position:

Rat Assembly	Chr	Position (strand)	Source
mRatBN7.2	10	39,101,395 - 39,156,424 (-)	NCBI
Rnor_6.0	10	40,320,581 - 40,375,605 (-)	NCBI
Rnor_5.0	10	40,092,956 - 40,148,308 (-)	NCBI
RGSC_v3.4	10	40,383,975 - 40,439,683 (-)	RGD
Celera	10	38,439,076 - 38,494,023 (-)	RGD

Sequence:

show sequence

CTGCGCTGCGGCTGCTGCTAGGCTAACGGGCTTCGAGCTGCGTCTATCTGTCTGCCCTGATCCG
AGGCCTCCCCAGAGCGTGGTTTCTGCTGCAGAACCTGAGACCATGGCCAAAATAGCACAGGGTG
CCATGTACCGAGGCTCTGTCCACGACTTCGCAGACTTTGATGCAAATCAGGATGCCGAGGCTTT
GTACACAGCCATGAAGGGCTTCGGCAGTGACAAGGAGTCCATATTGGAGCTGATCACCTCCCGC
AGCAACAAGCAGAGGCAGGAGATCTGCCAGAGTTACAAGTCCCTCTATGGCAAGGACCTCATCG
CAGACTTGAAGTATGAGTTGACAGGGAAGTTCGAGCGACTGATAGTGAACCTGATGAGGCCGCT
TGCCTATTGTGACGCCAAAGAGATTAAAGACGCTATCTCGGGCATTGGCACTGATGAGAAGTGC
CTCATTGAAATTTTGGCTTCCCGGACCAATGAGCAGATACACCAGCTGGTGGCCGCATACAAAG
ATGCCTATGAGAGAGACCTGGAGTCTGACATCATTGGAGACACTTCAGGCCACTTCCAGAAGAT
GCTGGTGGTACTGCTCCAGGGAACCCGGGAGAATGACGATGTTGTGAGTGAGGACTTGGTCCAG
CAGGATGTCCAGGACCTGTATGAGGCAGGGGAATTGAAATGGGGAACAGATGAGGCCCAGTTCA
TCTATATCTTGGGAAACCGTAGCAAACAGCACCTACGATTGGTGTTTGATGAGTACCTGAAGAC
CACAGGGAAGCCCATCGAAGCCAGTATCAGAGGGGAGCTGTCTGGAGACTTTGAGAAGCTGATG
TTGGCCGTGGTGAAGTGCATCCGAAGTACCCCGGAGTATTTTGCTGAAAGGCTGTTCAAAGCCA
TGAAGGGCCTGGGGACTCGAGACAACACTCTGATCCGTATCATGGTCTCCAGGAGCGAACTGGA
TATGCTTGACATCCGGGAGATCTTCCGGACCAAGTATGAGAAGTCACTCTACAGCATGATCAAG
AATGATACCTCTGGTGAATACAAGAAGGCTTTGCTGAAGCTATGTGGAGGGGACGATGATGCCG
CTGGCCAGTTCTTCCCGGAGGCAGCACAGGTGGCCTATCAGATGTGGGAACTTAGTGCAGTGTC
CCGAGTCGAGCTGAAGGGTACCGTGCGTGCGGCCAACGATTTCAACCCCGATGCTGATGCCAAG
GCCCTGCGGAAAGCCATGAAGGGAATTGGAACCGACGAAGCCACCATCATCGACATCATCACAC
AGCGCAGCAACGCCCAGCGGCAGCAGATCCGGCAGACCTTCAAATCTCACTTTGGCCGGGATTT
AATGGCCGACCTGAAGTCCGAGATCTCAGGAGACCTGGCAAGGCTGATCCTGGGGCTCATGATG
CCACCTGCCCATTACGATGCTAAGCAGCTGAAGAAAGCTATGGAGGGAGCCGGCACAGATGAAA
AGGCTCTTATAGAAATCCTGGCCACCCGGACCAATGCTGAAATCCGAGCCATCAATGAGGCCTA
CAAGGAGGATTATCACAAGTCCCTGGAGGATGCCCTGAGCTCGGACACATCTGGCCACTTCAAA
AGGATCCTCATTTCTCTGGCCACAGGGAATCGAGAGGAAGGAGGAGAAAACCGGGACCAGGCTC
AGGAAGATGCTCAGGTGGCTGCTGAGATCTTGGAAATAGCAGACACACCCAGTGGAGACAAAAC
CTCCTTGGAGACTCGATTCATGACCGTCCTGTGCACCCGTAGCTATCCCCACCTGCGCAGAGTC
TTCCAGGAGTTCATCAAGAAAACCAACTATGACATAGAGCATGTCATCAAGAAGGAGATGTCTG
GGGACGTCAAGGACGCATTTGTGGCCATCGTTCAGAGTGTCAAGAACAAGCCTCTCTTCTTTGC
TGACAAACTGTACAAGTCCATGAAGGGTGCCGGCACGGATGAGAAGACCCTCACCAGGGTGATG
GTGTCCCGGAGTGAGATAGACCTGCTCAACATCCGGAGGGAATTCATTGAGAAATATGACAAGT
CTCTACACCAAGCCATTGAAGGTGACACCTCTGGAGACTTCATGAAGGCTTTGCTGGCGCTCTG
TGGTGGAGAAGACTAAAACTCATGGCCTTGGAGGGTCCCCCCTGCCATGCAGTGGCCAACCGCA
CCAGCCACCGTGACCTGACCAAGCCATTGCTCCAGCTTCAGAGACTAAGGAAGAAGTGAGGGGT
GGAGTTGGACTGTGATCCGGCTGGGGTGCTCTCTTGCCATTGAGGGTCCCAGGCGGTCCCTTCT
GTTATCCCTCCTGCTCATGGCTAAGTGGCTGGTGAACCACAGCCATATATGCATTCAACCCTGC
TCCCCGTCTGCCTCCTCCTCCGCCCACCCTAGCTTCCATCCCTCCACACAATCCCTGCCTGATT
TAAGCTTTGTCACATCTCTAAACACACCAAACCTCTGTCTACGAAGTGAGTGACGTGTATGCTT
TGGAGGGTGGGCTGTGGTACCTGGTGCCAGGCATGCATTCTGGGATAGCGGAGATGATGAATTA
ATTTGATAGAGAGGTGATCTCCCCGGCCGTCACCATTCAATCTGATAAAAGTACCGAGCTCGGA
A

hide sequence

RefSeq Acc Id:

XM_006246340 ⟹ XP_006246402

Type:

CODING

Position:

Rat Assembly	Chr	Position (strand)	Source
mRatBN7.2	10	39,101,395 - 39,154,801 (-)	NCBI
Rnor_6.0	10	40,320,581 - 40,374,137 (-)	NCBI
Rnor_5.0	10	40,092,956 - 40,148,308 (-)	NCBI

Sequence:

show sequence

AGCACTGGAAAGCTTCCCGAGACCATACATACATCTGCACTGCAGCTCCCAGAGGAGTCCTGGA
CACGAGGCCTGGCCCCGCCCCATCTCTGCCCCTCCACCCACAAAGCTGGGCACCTCCCCACCTT
GATTCATTCCTCCCTGGAGGAGGAGACCAGTACCCAGGCCCCCCAACTGTGGTTTCTGCTGCAG
AACCTGAGACCATGGCCAAAATAGCACAGGGTGCCATGTACCGAGGCTCTGTCCACGACTTCGC
AGACTTTGATGCAAATCAGGATGCCGAGGCTTTGTACACAGCCATGAAGGGCTTCGGCAGTGAC
AAGGAGTCCATATTGGAGCTGATCACCTCCCGCAGCAACAAGCAGAGGCAGGAGATCTGCCAGA
GTTACAAGTCCCTCTATGGCAAGGACCTCATCGCAGACTTGAAGTATGAGTTGACAGGGAAGTT
CGAGCGACTGATAGTGAACCTGATGAGGCCGCTTGCCTATTGTGACGCCAAAGAGATTAAAGAC
GCTATCTCGGGCATTGGCACTGATGAGAAGTGCCTCATTGAAATTTTGGCTTCCCGGACCAATG
AGCAGATACACCAGCTGGTGGCCGCATACAAAGATGCCTATGAGAGAGACCTGGAGTCTGACAT
CATTGGAGACACTTCAGGCCACTTCCAGAAGATGCTGGTGGTACTGCTCCAGGGAACCCGGGAG
AATGACGATGTTGTGAGTGAGGACTTGGTCCAGCAGGATGTCCAGGACCTGTATGAGGCAGGGG
AATTGAAATGGGGAACAGATGAGGCCCAGTTCATCTATATCTTGGGAAACCGTAGCAAACAGCA
CCTACGATTGGTGTTTGATGAGTACCTGAAGACCACAGGGAAGCCCATCGAAGCCAGTATCAGA
GGGGAGCTGTCTGGAGACTTTGAGAAGCTGATGTTGGCCGTGGTGAAGTGCATCCGAAGTACCC
CGGAGTATTTTGCTGAAAGGCTGTTCAAAGCCATGAAGGGCCTGGGGACTCGAGACAACACTCT
GATCCGTATCATGGTCTCCAGGAGCGAACTGGATATGCTTGACATCCGGGAGATCTTCCGGACC
AAGTATGAGAAGTCACTCTACAGCATGATCAAGAATGATACCTCTGGTGAATACAAGAAGGCTT
TGCTGAAGCTATGTGGAGGGGACGATGATGCCGCTGGCCAGTTCTTCCCGGAGGCAGCACAGGT
GGCCTATCAGATGTGGGAACTTAGTGCAGTGTCCCGAGTCGAGCTGAAGGGTACCGTGCGTGCG
GCCAACGATTTCAACCCCGATGCTGATGCCAAGGCCCTGCGGAAAGCCATGAAGGGAATTGGAA
CCGACGAAGCCACCATCATCGACATCATCACACAGCGCAGCAACGCCCAGCGGCAGCAGATCCG
GCAGACCTTCAAATCTCACTTTGGCCGGGATTTAATGGCCGACCTGAAGTCCGAGATCTCAGGA
GACCTGGCAAGGCTGATCCTGGGGCTCATGATGCCACCTGCCCATTACGATGCTAAGCAGCTGA
AGAAAGCTATGGAGGGAGCCGGCACAGATGAAAAGGCTCTTATAGAAATCCTGGCCACCCGGAC
CAATGCTGAAATCCGAGCCATCAATGAGGCCTACAAGGAGGATTATCACAAGTCCCTGGAGGAT
GCCCTGAGCTCGGACACATCTGGCCACTTCAAAAGGATCCTCATTTCTCTGGCCACAGGGAATC
GAGAGGAAGGAGGAGAAAACCGGGACCAGGCTCAGGAAGATGCTCAGGTGGCTGCTGAGATCTT
GGAAATAGCAGACACACCCAGTGGAGACAAAACCTCCTTGGAGACTCGATTCATGACCGTCCTG
TGCACCCGTAGCTATCCCCACCTGCGCAGAGTCTTCCAGGAGTTCATCAAGAAAACCAACTATG
ACATAGAGCATGTCATCAAGAAGGAGATGTCTGGGGACGTCAAGGACGCATTTGTGGCCATCGT
TCAGAGTGTCAAGAACAAGCCTCTCTTCTTTGCTGACAAACTGTACAAGTCCATGAAGGGTGCC
GGCACGGATGAGAAGACCCTCACCAGGGTGATGGTGTCCCGGAGTGAGATAGACCTGCTCAACA
TCCGGAGGGAATTCATTGAGAAATATGACAAGTCTCTACACCAAGCCATTGAAGGTGACACCTC
TGGAGACTTCATGAAGGCTTTGCTGGCGCTCTGTGGTGGAGAAGACTAAAACTCATGGCCTTGG
AGGGTCCCCCCTGCCATGCAGTGGCCAACCGCACCAGCCACCGTGACCTGACCAAGCCATTGCT
CCAGCTTCAGAGACTAAGGAAGAAGTGAGGGGTGGAGTTGGACTGTGATCCGGCTGGGGTGCTC
TCTTGCCATTGAGGGTCCCAGGCGGTCCCTTCTGTTATCCCTCCTGCTCATGGCTAAGTGGCTG
GTGAACCACAGCCATATATGCATTCAACCCTGCTCCCCGTCTGCCTCCTCCTCCGCCCACCCTA
GCTTCCATCCCTCCACACAATCCCTGCCTGATTTAAGCTTTGTCACATCTCTAAACACACCAAA
CCTCTGTCTACGAAGTGAGTGACGTGTATGCTTTGGAGGGTGGGCTGTGGTACCTGGTGCCAGG
CATGCATTCTGGGATAGCGGAGATGATGAATTAATTTGATAGAGAGGTGATCTCCCCGGCCGTC
ACCATTCAATCTGATAAAAGTACCGAGCTCGGAA

hide sequence

RefSeq Acc Id:

XM_006246341 ⟹ XP_006246403

Type:

CODING

Position:

Rat Assembly	Chr	Position (strand)	Source
mRatBN7.2	10	39,101,395 - 39,154,802 (-)	NCBI
Rnor_6.0	10	40,320,581 - 40,374,139 (-)	NCBI
Rnor_5.0	10	40,092,956 - 40,148,308 (-)	NCBI

Sequence:

show sequence

GCAGCACTGGAAAGCTTCCCGAGACCATACATACATCTGCACTGCAGCTCCCAGAGGAGTCCTG
GACACGAGGCCTGGCCCCGCCCCATCTCTGCCCCTCCACCCACAAAGCTGGGCACCTCCCCACC
TTGATTCATTCCTCCCTGGAGGAGGAGACCAGTACCCAGGCCCCCCAACTGTGGTTTCTGCTGC
AGAACCTGAGACCATGGCCAAAATAGCACAGGGTGCCATGTACCGAGGCTCTGTCCACGACTTC
GCAGACTTTGATGCAAATCAGGATGCCGAGGCTTTGTACACAGCCATGAAGGGCTTCGGCAGTG
ACAAGGAGTCCATATTGGAGCTGATCACCTCCCGCAGCAACAAGCAGAGGCAGGAGATCTGCCA
GAGTTACAAGTCCCTCTATGGCAAGGACCTCATCGCAGACTTGAAGTATGAGTTGACAGGGAAG
TTCGAGCGACTGATAGTGAACCTGATGAGGCCGCTTGCCTATTGTGACGCCAAAGAGATTAAAG
ACGCTATCTCGGGCATTGGCACTGATGAGAAGTGCCTCATTGAAATTTTGGCTTCCCGGACCAA
TGAGCAGATACACCAGCTGGTGGCCGCATACAAAGATGCCTATGAGAGAGACCTGGAGTCTGAC
ATCATTGGAGACACTTCAGGCCACTTCCAGAAGATGCTGGTGGTACTGCTCCAGGGAACCCGGG
AGAATGACGATGTTGTGAGTGAGGACTTGGTCCAGCAGGATGTCCAGGACCTGTATGAGGCAGG
GGAATTGAAATGGGGAACAGATGAGGCCCAGTTCATCTATATCTTGGGAAACCGTAGCAAACAG
CACCTACGATTGGTGTTTGATGAGTACCTGAAGACCACAGGGAAGCCCATCGAAGCCAGTATCA
GAGGGGAGCTGTCTGGAGACTTTGAGAAGCTGATGTTGGCCGTGGTGAAGTGCATCCGAAGTAC
CCCGGAGTATTTTGCTGAAAGGCTGTTCAAAGCCATGAAGGGCCTGGGGACTCGAGACAACACT
CTGATCCGTATCATGGTCTCCAGGAGCGAACTGGATATGCTTGACATCCGGGAGATCTTCCGGA
CCAAGTATGAGAAGTCACTCTACAGCATGATCAAGAATGATACCTCTGGTGAATACAAGAAGGC
TTTGCTGAAGCTATGTGGAGGGGACGATGATGCCGCTGGCCAGTTCTTCCCGGAGGCAGCACAG
GTGGCCTATCAGATGTGGGAACTTAGTGCAGTGTCCCGAGTCGAGCTGAAGGGTACCGTGCGTG
CGGCCAACGATTTCAACCCCGATGCTGATGCCAAGGCCCTGCGGAAAGCCATGAAGGGAATTGG
AACCGACGAAGCCACCATCATCGACATCATCACACAGCGCAGCAACGCCCAGCGGCAGCAGATC
CGGCAGACCTTCAAATCTCACTTTGGCCGGGATTTAATGGCCGACCTGAAGTCCGAGATCTCAG
GAGACCTGGCAAGGCTGATCCTGGGGCTCATGATGCCACCTGCCCATTACGATGCTAAGCAGCT
GAAGAAAGCTATGGAGGGAGCCGGCACAGATGAAAAGGCTCTTATAGAAATCCTGGCCACCCGG
ACCAATGCTGAAATCCGAGCCATCAATGAGGCCTACAAGGAGGATTATCACAAGTCCCTGGAGG
ATGCCCTGAGCTCGGACACATCTGGCCACTTCAAAAGGATCCTCATTTCTCTGGCCACAGGGAA
TCGAGAGGAAGGAGGAGAAAACCGGGACCAGGCTCAGGAAGATGCTCAGGAAATAGCAGACACA
CCCAGTGGAGACAAAACCTCCTTGGAGACTCGATTCATGACCGTCCTGTGCACCCGTAGCTATC
CCCACCTGCGCAGAGTCTTCCAGGAGTTCATCAAGAAAACCAACTATGACATAGAGCATGTCAT
CAAGAAGGAGATGTCTGGGGACGTCAAGGACGCATTTGTGGCCATCGTTCAGAGTGTCAAGAAC
AAGCCTCTCTTCTTTGCTGACAAACTGTACAAGTCCATGAAGGGTGCCGGCACGGATGAGAAGA
CCCTCACCAGGGTGATGGTGTCCCGGAGTGAGATAGACCTGCTCAACATCCGGAGGGAATTCAT
TGAGAAATATGACAAGTCTCTACACCAAGCCATTGAAGGTGACACCTCTGGAGACTTCATGAAG
GCTTTGCTGGCGCTCTGTGGTGGAGAAGACTAAAACTCATGGCCTTGGAGGGTCCCCCCTGCCA
TGCAGTGGCCAACCGCACCAGCCACCGTGACCTGACCAAGCCATTGCTCCAGCTTCAGAGACTA
AGGAAGAAGTGAGGGGTGGAGTTGGACTGTGATCCGGCTGGGGTGCTCTCTTGCCATTGAGGGT
CCCAGGCGGTCCCTTCTGTTATCCCTCCTGCTCATGGCTAAGTGGCTGGTGAACCACAGCCATA
TATGCATTCAACCCTGCTCCCCGTCTGCCTCCTCCTCCGCCCACCCTAGCTTCCATCCCTCCAC
ACAATCCCTGCCTGATTTAAGCTTTGTCACATCTCTAAACACACCAAACCTCTGTCTACGAAGT
GAGTGACGTGTATGCTTTGGAGGGTGGGCTGTGGTACCTGGTGCCAGGCATGCATTCTGGGATA
GCGGAGATGATGAATTAATTTGATAGAGAGGTGATCTCCCCGGCCGTCACCATTCAATCTGATA
AAAGTACCGAGCTCGGAA

hide sequence

RefSeq Acc Id:

XM_039086912 ⟹ XP_038942840

Type:

CODING

Position:

Rat Assembly	Chr	Position (strand)	Source
mRatBN7.2	10	39,101,395 - 39,156,483 (-)	NCBI

Protein Sequences


Protein RefSeqs	NP_077070	(Get FASTA)	NCBI Sequence Viewer
	XP_006246402	(Get FASTA)	NCBI Sequence Viewer
	XP_006246403	(Get FASTA)	NCBI Sequence Viewer
	XP_038942840	(Get FASTA)	NCBI Sequence Viewer
GenBank Protein	AAH72523	(Get FASTA)	NCBI Sequence Viewer
	EDM04457	(Get FASTA)	NCBI Sequence Viewer
	P48037	(Get FASTA)	NCBI Sequence Viewer

RefSeq Acc Id:

NP_077070 ⟸ NM_024156

- UniProtKB:

P48037 (UniProtKB/Swiss-Prot), Q6IMZ3 (UniProtKB/TrEMBL), D4ABR6 (UniProtKB/TrEMBL)

- Sequence:

show sequence

MAKIAQGAMYRGSVHDFADFDANQDAEALYTAMKGFGSDKESILELITSRSNKQRQEICQSYKS
LYGKDLIADLKYELTGKFERLIVNLMRPLAYCDAKEIKDAISGIGTDEKCLIEILASRTNEQIH
QLVAAYKDAYERDLESDIIGDTSGHFQKMLVVLLQGTRENDDVVSEDLVQQDVQDLYEAGELKW
GTDEAQFIYILGNRSKQHLRLVFDEYLKTTGKPIEASIRGELSGDFEKLMLAVVKCIRSTPEYF
AERLFKAMKGLGTRDNTLIRIMVSRSELDMLDIREIFRTKYEKSLYSMIKNDTSGEYKKALLKL
CGGDDDAAGQFFPEAAQVAYQMWELSAVSRVELKGTVRAANDFNPDADAKALRKAMKGIGTDEA
TIIDIITQRSNAQRQQIRQTFKSHFGRDLMADLKSEISGDLARLILGLMMPPAHYDAKQLKKAM
EGAGTDEKALIEILATRTNAEIRAINEAYKEDYHKSLEDALSSDTSGHFKRILISLATGNREEG
GENRDQAQEDAQVAAEILEIADTPSGDKTSLETRFMTVLCTRSYPHLRRVFQEFIKKTNYDIEH
VIKKEMSGDVKDAFVAIVQSVKNKPLFFADKLYKSMKGAGTDEKTLTRVMVSRSEIDLLNIRRE
FIEKYDKSLHQAIEGDTSGDFMKALLALCGGED

hide sequence

RefSeq Acc Id:	XP_006246403 ⟸ XM_006246341
- Peptide Label:	isoform X2
- UniProtKB:	A0A8I5ZMD4 (UniProtKB/TrEMBL), A0A8J8XVA7 (UniProtKB/TrEMBL)
- Sequence:	show sequence MAKIAQGAMYRGSVHDFADFDANQDAEALYTAMKGFGSDKESILELITSRSNKQRQEICQSYKS LYGKDLIADLKYELTGKFERLIVNLMRPLAYCDAKEIKDAISGIGTDEKCLIEILASRTNEQIH QLVAAYKDAYERDLESDIIGDTSGHFQKMLVVLLQGTRENDDVVSEDLVQQDVQDLYEAGELKW GTDEAQFIYILGNRSKQHLRLVFDEYLKTTGKPIEASIRGELSGDFEKLMLAVVKCIRSTPEYF AERLFKAMKGLGTRDNTLIRIMVSRSELDMLDIREIFRTKYEKSLYSMIKNDTSGEYKKALLKL CGGDDDAAGQFFPEAAQVAYQMWELSAVSRVELKGTVRAANDFNPDADAKALRKAMKGIGTDEA TIIDIITQRSNAQRQQIRQTFKSHFGRDLMADLKSEISGDLARLILGLMMPPAHYDAKQLKKAM EGAGTDEKALIEILATRTNAEIRAINEAYKEDYHKSLEDALSSDTSGHFKRILISLATGNREEG GENRDQAQEDAQEIADTPSGDKTSLETRFMTVLCTRSYPHLRRVFQEFIKKTNYDIEHVIKKEM SGDVKDAFVAIVQSVKNKPLFFADKLYKSMKGAGTDEKTLTRVMVSRSEIDLLNIRREFIEKYD KSLHQAIEGDTSGDFMKALLALCGGED hide sequence

RefSeq Acc Id:	XP_006246402 ⟸ XM_006246340
- Peptide Label:	isoform X1
- UniProtKB:	P48037 (UniProtKB/Swiss-Prot), Q6IMZ3 (UniProtKB/TrEMBL), D4ABR6 (UniProtKB/TrEMBL)
- Sequence:	show sequence MAKIAQGAMYRGSVHDFADFDANQDAEALYTAMKGFGSDKESILELITSRSNKQRQEICQSYKS LYGKDLIADLKYELTGKFERLIVNLMRPLAYCDAKEIKDAISGIGTDEKCLIEILASRTNEQIH QLVAAYKDAYERDLESDIIGDTSGHFQKMLVVLLQGTRENDDVVSEDLVQQDVQDLYEAGELKW GTDEAQFIYILGNRSKQHLRLVFDEYLKTTGKPIEASIRGELSGDFEKLMLAVVKCIRSTPEYF AERLFKAMKGLGTRDNTLIRIMVSRSELDMLDIREIFRTKYEKSLYSMIKNDTSGEYKKALLKL CGGDDDAAGQFFPEAAQVAYQMWELSAVSRVELKGTVRAANDFNPDADAKALRKAMKGIGTDEA TIIDIITQRSNAQRQQIRQTFKSHFGRDLMADLKSEISGDLARLILGLMMPPAHYDAKQLKKAM EGAGTDEKALIEILATRTNAEIRAINEAYKEDYHKSLEDALSSDTSGHFKRILISLATGNREEG GENRDQAQEDAQVAAEILEIADTPSGDKTSLETRFMTVLCTRSYPHLRRVFQEFIKKTNYDIEH VIKKEMSGDVKDAFVAIVQSVKNKPLFFADKLYKSMKGAGTDEKTLTRVMVSRSEIDLLNIRRE FIEKYDKSLHQAIEGDTSGDFMKALLALCGGED hide sequence

RefSeq Acc Id:

ENSRNOP00000014464 ⟸ ENSRNOT00000014464

RefSeq Acc Id:	XP_038942840 ⟸ XM_039086912
- Peptide Label:	isoform X2
- UniProtKB:	A0A8I5ZMD4 (UniProtKB/TrEMBL), A0A8J8XVA7 (UniProtKB/TrEMBL)

RefSeq Acc Id:

ENSRNOP00000080378 ⟸ ENSRNOT00000111975

RefSeq Acc Id:

ENSRNOP00000091681 ⟸ ENSRNOT00000096029

RefSeq Acc Id:

ENSRNOP00000076795 ⟸ ENSRNOT00000119845

RefSeq Acc Id:

ENSRNOP00000079087 ⟸ ENSRNOT00000106165

Protein Structures

Name	Modeler	Protein Id	AA Range	Protein Structure
AF-P48037-F1-model_v2	AlphaFold	P48037	1-673	view protein structure

Transcriptome

eQTL		View at Phenogen
WGCNA		View at Phenogen
Tissue/Strain Expression		View at Phenogen

Additional Information

External Database Links

Database	Acc Id	Source(s)
AGR Gene	RGD:621172	AgrOrtholog
BioCyc Gene	G2FUF-25095	BioCyc
Ensembl Genes	ENSRNOG00000010668	Ensembl, ENTREZGENE, UniProtKB/TrEMBL
Ensembl Protein	ENSRNOP00000014464.7	UniProtKB/TrEMBL
	ENSRNOP00000076795.1	UniProtKB/TrEMBL
	ENSRNOP00000079087	ENTREZGENE
	ENSRNOP00000079087.1	UniProtKB/TrEMBL
	ENSRNOP00000080378	ENTREZGENE
	ENSRNOP00000080378.1	UniProtKB/TrEMBL
	ENSRNOP00000091681	ENTREZGENE
	ENSRNOP00000091681.1	UniProtKB/TrEMBL
Ensembl Transcript	ENSRNOT00000014464.8	UniProtKB/TrEMBL
	ENSRNOT00000096029	ENTREZGENE
	ENSRNOT00000096029.1	UniProtKB/TrEMBL
	ENSRNOT00000106165	ENTREZGENE
	ENSRNOT00000106165.1	UniProtKB/TrEMBL
	ENSRNOT00000111975	ENTREZGENE
	ENSRNOT00000111975.1	UniProtKB/TrEMBL
	ENSRNOT00000119845.1	UniProtKB/TrEMBL
Gene3D-CATH	1.10.220.10	UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
IMAGE_CLONE	IMAGE:7105847	IMAGE-MGC_LOAD
InterPro	Annexin	UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
	Annexin_repeat	UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
	Annexin_repeat_CS	UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
	Annexin_sf	UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
	ANX6	UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
KEGG Report	rno:79125	UniProtKB/TrEMBL
MGC_CLONE	MGC:91612	IMAGE-MGC_LOAD
NCBI Gene	79125	ENTREZGENE
PANTHER	ANNEXIN	UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
	ANNEXIN A6	UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
Pfam	Annexin	UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
PhenoGen	Anxa6	PhenoGen
PRINTS	ANNEXIN	UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
	ANNEXINVI	UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
PROSITE	ANNEXIN	UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
	ANNEXIN_2	UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
SMART	ANX	UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
Superfamily-SCOP	SSF47874	UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
UniProt	A0A8I5ZJA4_RAT	UniProtKB/TrEMBL
	A0A8I5ZMD4	ENTREZGENE, UniProtKB/TrEMBL
	A0A8I6AE49_RAT	UniProtKB/TrEMBL
	A0A8I6G4G4_RAT	UniProtKB/TrEMBL
	A0A8J8XVA7	ENTREZGENE, UniProtKB/TrEMBL
	ANXA6_RAT	UniProtKB/Swiss-Prot
	D4ABR6	ENTREZGENE
	P48037	ENTREZGENE
	Q6IMZ3	ENTREZGENE, UniProtKB/TrEMBL
UniProt Secondary	D4ABR6	UniProtKB/TrEMBL

Nomenclature History

Date	Current Symbol	Current Name	Previous Symbol	Previous Name	Description	Reference	Status
2004-09-10	Anxa6	annexin A6		annexin VI	Name updated	1299863	APPROVED
2002-08-07	Anxa6	annexin VI			Symbol and Name status set to provisional	70820	PROVISIONAL

RGD Curation Notes

Note Type	Note	Reference
gene_physical_interaction	may associate with cd21	724707
gene_process	may regulate the release of ca(2+) from intracellular stores	724707

Gene Annotator (Functional Annotation) unavailable	Gene Annotator (Annotation Distribution) unavailable	Variant Visualizer (Genomic Variants) unavailble Variant Visualizer (Genomic Variants) unavailable
Gene Annotator (Functional Annotation)	Gene Annotator (Annotation Distribution)	Variant Visualizer (Genomic Variants)

InterViewer (Protein-Protein Interactions) unavailable	Gviewer (Genome Viewer) unavailable	Variant Visualizer (Damaging Variants) unavailble Variant Visualizer (Damaging Variants) unavailable
InterViewer (Protein-Protein Interactions)	GViewer (Genome Viewer)	Variant Visualizer (Damaging Variants)

Gene Annotator (Annotation Comparison) unavailable	OLGA (Gene List Generator) unavailable
Gene Annotator (Annotation Comparison)	OLGA (Gene List Generator)	Excel (Download)

MOET (Multi-Ontology Enrichement) unavailable	GOLF (Gene-Ortholog Location Finder) unavailable
MOET (Multi-Ontology Enrichement)	GOLF (Gene-Ortholog Location Finder)

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