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Gene: P2rx1 (purinergic receptor P2X 1) Rattus norvegicus
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Symbol: P2rx1
Name: purinergic receptor P2X 1
Description: Exhibits ATP binding activity; extracellularly ATP-gated cation channel activity; and zinc ion binding activity. Involved in several processes, including glutamatergic synaptic transmission; neuronal action potential; and protein complex oligomerization. Localizes to several cellular components, including the glutamatergic synapse; integral component of synaptic membrane; and membrane raft. Orthologous to human P2RX1 (purinergic receptor P2X 1); PARTICIPATES IN calcium/calcium-mediated signaling pathway; INTERACTS WITH (S)-10-[(DIMETHYLAMINO)METHYL]-4-ETHYL-4,9-DIHYDROXY-1H-PYRANO[3',4':6,7]INOLIZINO[1,2-B]-QUINOLINE-3,14(4H,12H)-DIONE; 17beta-estradiol; aflatoxin B1.
Type: protein-coding
RefSeq Status: VALIDATED
Also known as: ATP receptor; P2X purinoceptor 1; P2X1; P2XMR; purinergic receptor P2X, ligand-gated ion channel, 1; RP-2 protein
Orthologs:
Homo sapiens (human) : P2RX1 (purinergic receptor P2X 1)  HGNC  Alliance
Mus musculus (house mouse) : P2rx1 (purinergic receptor P2X, ligand-gated ion channel, 1)  MGI  Alliance
Chinchilla lanigera (long-tailed chinchilla) : P2rx1 (purinergic receptor P2X 1)
Pan paniscus (bonobo/pygmy chimpanzee) : P2RX1 (purinergic receptor P2X 1)
Canis lupus familiaris (dog) : P2RX1 (purinergic receptor P2X 1)
Ictidomys tridecemlineatus (thirteen-lined ground squirrel) : P2rx1 (purinergic receptor P2X 1)
Sus scrofa (pig) : P2RX1 (purinergic receptor P2X 1)
more info ...
Allele / Splice: P2rx1em1Mcwi   P2rx1em6Mcwi   P2rx1em7Mcwi  
Genetic Models: SS-P2rx1em7Mcwi SS-P2rx1em6Mcwi SS-P2rx1em1Mcwi
Latest Assembly: Rnor_6.0 - RGSC Genome Assembly v6.0
Position:
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Rnor_6.01059,566,268 - 59,581,328 (+)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_5.01059,305,737 - 59,320,797 (+)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.41059,889,933 - 59,904,985 (+)NCBIRGSC3.4rn4RGSC3.4
RGSC_v3.11059,903,555 - 59,918,605 (+)NCBI
Celera1056,742,815 - 56,757,878 (+)NCBICelera
Cytogenetic Map10q24NCBI
JBrowse: View Region in Genome Browser (JBrowse)
Model


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Genomics

Comparative Map Data
Position Markers
QTLs in Region (Rnor_6.0)
Genetic Models
miRNA Target Status

Sequence

Nucleotide Sequences
Protein Sequences
Transcriptome
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Strain Variation

Strain Sequence Variants (Rnor 5.0)

Additional Information

External Database Links
Nomenclature History
RGD Curation Notes
 
More on P2rx1
Alliance Gene
NCBI Gene
Ensembl Gene
JBrowse: rn5 rn6
NCBI Genome Data Viewer

RGD Object Information
RGD ID: 3240
Created: 2000-05-25
Species: Rattus norvegicus
Last Modified: 2019-04-23
Status: ACTIVE



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RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.