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Gene-Chemical Interaction Annotations Click to see Annotation Detail View
Term | Qualifier | Evidence | With | Reference | Notes | Source | Original Reference(s) | (-)-epigallocatechin 3-gallate | multiple interactions | ISO | RGD:735923 | 6480464 | [potassium chromate(VI) co-treated with epigallocatechin gallate] results in decreased expression of ADAM19 mRNA | CTD | PMID:22079256 | (S)-nicotine | increases expression | ISO | RGD:735923 | 6480464 | Nicotine results in increased expression of ADAM19 mRNA | CTD | PMID:23825647 | 1,2-dichloroethane | decreases expression | ISO | RGD:735924 | 6480464 | ethylene dichloride results in decreased expression of ADAM19 mRNA | CTD | PMID:28960355 | 1,2-dimethylhydrazine | affects expression | ISO | RGD:735924 | 6480464 | 1, 2-Dimethylhydrazine affects the expression of ADAM19 mRNA | CTD | PMID:22206623 | 17beta-estradiol | multiple interactions | ISO | RGD:735923 | 6480464 | [Estradiol co-treated with TGFB1 protein] results in increased expression of ADAM19 mRNA | CTD | PMID:30165855 | 2,3,7,8-tetrachlorodibenzodioxine | multiple interactions | ISO | RGD:735923 | 6480464 | [Triiodothyronine co-treated with Tetrachlorodibenzodioxin] results in decreased expression of ADAM19 mRNA | CTD | PMID:14761676 | 2,3,7,8-tetrachlorodibenzodioxine | affects expression | EXP | | 6480464 | Tetrachlorodibenzodioxin affects the expression of ADAM19 mRNA | CTD | PMID:34747641 | 2,3,7,8-tetrachlorodibenzodioxine | increases expression | ISO | RGD:735924 | 6480464 | Tetrachlorodibenzodioxin results in increased expression of ADAM19 mRNA | CTD | PMID:29673856 | 2-methoxyethanol | increases expression | EXP | | 6480464 | methyl cellosolve results in increased expression of ADAM19 mRNA | CTD | PMID:21061450 | 3,3',5-triiodo-L-thyronine | multiple interactions | ISO | RGD:735923 | 6480464 | [Triiodothyronine co-treated with Tetrachlorodibenzodioxin] results in decreased expression of ADAM19 mRNA | CTD | PMID:14761676 | 3,4-methylenedioxymethamphetamine | decreases expression | ISO | RGD:735924 | 6480464 | N-Methyl-3, 4-methylenedioxyamphetamine results in decreased expression of ADAM19 mRNA | CTD | PMID:26251327 | 3-isobutyl-1-methyl-7H-xanthine | multiple interactions | ISO | RGD:735923 | 6480464 | [INS protein co-treated with Dexamethasone co-treated with 1-Methyl-3-isobutylxanthine co-treated with Indomethacin] results in decreased expression of ADAM19 mRNA | CTD | PMID:28628672 | 4,4'-sulfonyldiphenol | increases expression | ISO | RGD:735924 | 6480464 | bis(4-hydroxyphenyl)sulfone results in increased expression of ADAM19 mRNA | CTD | PMID:30951980 | 5-aza-2'-deoxycytidine | affects expression | ISO | RGD:735923 | 6480464 | Decitabine affects the expression of ADAM19 mRNA | CTD | PMID:23300844 | 6-propyl-2-thiouracil | decreases expression | EXP | | 6480464 | Propylthiouracil results in decreased expression of ADAM19 mRNA | CTD | PMID:24780913 | acetamide | increases expression | EXP | | 6480464 | acetamide results in increased expression of ADAM19 mRNA | CTD | PMID:31881176 | acrylamide | decreases expression | ISO | RGD:735923 | 6480464 | Acrylamide results in decreased expression of ADAM19 mRNA | CTD | PMID:32763439 | aflatoxin B1 | decreases methylation | ISO | RGD:735923 | 6480464 | Aflatoxin B1 results in decreased methylation of ADAM19 intron | CTD | PMID:30157460 | all-trans-retinoic acid | decreases expression | ISO | RGD:735924 | 6480464 | Tretinoin results in decreased expression of ADAM19 mRNA | CTD | PMID:16604517 | all-trans-retinoic acid | increases expression | ISO | RGD:735923 | 6480464 | Tretinoin results in increased expression of ADAM19 mRNA | CTD | PMID:23724009, PMID:23830798 | benzo[a]pyrene | increases methylation | ISO | RGD:735924 | 6480464 | Benzo(a)pyrene results in increased methylation of ADAM19 exon, Benzo(a)pyrene results in increased methylation of ADAM19 intron | CTD | PMID:27901495 | benzo[a]pyrene | increases expression | ISO | RGD:735923 | 6480464 | Benzo(a)pyrene results in increased expression of ADAM19 mRNA | CTD | PMID:32234424 | beta-naphthoflavone | decreases expression | ISO | RGD:735923 | 6480464 | beta-Naphthoflavone results in decreased expression of ADAM19 mRNA | CTD | PMID:32858204 | bis(2-ethylhexyl) phthalate | increases expression | ISO | RGD:735923 | 6480464 | Diethylhexyl Phthalate results in increased expression of ADAM19 mRNA | CTD | PMID:31163220 | bisphenol A | affects expression | EXP | | 6480464 | bisphenol A affects the expression of ADAM19 mRNA | CTD | PMID:25181051 | bisphenol A | increases expression | ISO | RGD:735924 | 6480464 | bisphenol A results in increased expression of ADAM19 mRNA | CTD | PMID:30951980, PMID:32370801 | bisphenol A | decreases expression | ISO | RGD:735923 | 6480464 | bisphenol A results in decreased expression of ADAM19 mRNA | CTD | PMID:29275510 | bisphenol F | increases expression | ISO | RGD:735924 | 6480464 | bisphenol F results in increased expression of ADAM19 mRNA | CTD | PMID:30951980 | butanal | increases expression | ISO | RGD:735923 | 6480464 | butyraldehyde results in increased expression of ADAM19 mRNA | CTD | PMID:26079696 | C60 fullerene | decreases expression | EXP | | 6480464 | fullerene C60 results in decreased expression of ADAM19 mRNA | CTD | PMID:19167457 | calcitriol | increases expression | ISO | RGD:735923 | 6480464 | Calcitriol results in increased expression of ADAM19 mRNA | CTD | PMID:16002434 | camptothecin | decreases response to substance | ISO | RGD:735923 | 6480464 | ADAM19 mRNA results in decreased susceptibility to Camptothecin | CTD | PMID:25269479 | carbamazepine | affects expression | ISO | RGD:735923 | 6480464 | Carbamazepine affects the expression of ADAM19 mRNA | CTD | PMID:25979313 | CGP 52608 | multiple interactions | ISO | RGD:735923 | 6480464 | CGP 52608 promotes the reaction [RORA protein binds to ADAM19 gene] | CTD | PMID:28238834 | choline | multiple interactions | ISO | RGD:735924 | 6480464 | [Methionine deficiency co-treated with Choline deficiency co-treated with Folic Acid deficiency] results in increased expression of ADAM19 mRNA | CTD | PMID:20938992 | cisplatin | affects expression | ISO | RGD:735923 | 6480464 | Cisplatin affects the expression of ADAM19 mRNA | CTD | PMID:23300844 | cisplatin | decreases expression | ISO | RGD:735923 | 6480464 | Cisplatin results in decreased expression of ADAM19 mRNA | CTD | PMID:27392435 | cisplatin | multiple interactions | ISO | RGD:735923 | 6480464 | [Cisplatin co-treated with jinfukang] results in decreased expression of ADAM19 mRNA | CTD | PMID:27392435 | cocaine | decreases expression | EXP | | 6480464 | Cocaine results in decreased expression of ADAM19 mRNA | CTD | PMID:17898221 | copper(II) sulfate | increases expression | ISO | RGD:735923 | 6480464 | Copper Sulfate results in increased expression of ADAM19 mRNA | CTD | PMID:19549813 | cyclosporin A | increases expression | ISO | RGD:735923 | 6480464 | Cyclosporine results in increased expression of ADAM19 mRNA | CTD | PMID:25562108 | cyclosporin A | decreases expression | ISO | RGD:735923 | 6480464 | Cyclosporine results in decreased expression of ADAM19 mRNA | CTD | PMID:27989131 | cytarabine | decreases expression | ISO | RGD:735923 | 6480464 | Cytarabine results in decreased expression of ADAM19 mRNA | CTD | PMID:21198554 | dexamethasone | multiple interactions | ISO | RGD:735923 | 6480464 | [INS protein co-treated with Dexamethasone co-treated with 1-Methyl-3-isobutylxanthine co-treated with Indomethacin] results in decreased expression of ADAM19 mRNA | CTD | PMID:28628672 | dibutyl phthalate | increases expression | EXP | | 6480464 | Dibutyl Phthalate results in increased expression of ADAM19 mRNA | CTD | PMID:21266533 | doxorubicin | decreases expression | ISO | RGD:735923 | 6480464 | Doxorubicin results in decreased expression of ADAM19 mRNA | CTD | PMID:18510171, PMID:29803840 | endosulfan | decreases expression | EXP | | 6480464 | Endosulfan results in decreased expression of ADAM19 mRNA | CTD | PMID:29391264 | ethanol | affects splicing | ISO | RGD:735924 | 6480464 | Ethanol affects the splicing of ADAM19 mRNA | CTD | PMID:30319688 | folic acid | multiple interactions | ISO | RGD:735924 | 6480464 | [Methionine deficiency co-treated with Choline deficiency co-treated with Folic Acid deficiency] results in increased expression of ADAM19 mRNA | CTD | PMID:20938992 | furan | increases expression | EXP | | 6480464 | furan results in increased expression of ADAM19 mRNA | CTD | PMID:27387713 | gentamycin | decreases expression | EXP | | 6480464 | Gentamicins results in decreased expression of ADAM19 mRNA | CTD | PMID:33387578 | hydroquinone O-beta-D-glucopyranoside | decreases expression | ISO | RGD:735923 | 6480464 | Arbutin results in decreased expression of ADAM19 mRNA | CTD | PMID:17103032 | indometacin | multiple interactions | ISO | RGD:735923 | 6480464 | [INS protein co-treated with Dexamethasone co-treated with 1-Methyl-3-isobutylxanthine co-treated with Indomethacin] results in decreased expression of ADAM19 mRNA | CTD | PMID:28628672 | irinotecan | increases expression | ISO | RGD:735923 | 6480464 | Irinotecan analog results in increased expression of ADAM19 mRNA | CTD | PMID:18927307 | L-methionine | multiple interactions | ISO | RGD:735924 | 6480464 | [Methionine deficiency co-treated with Choline deficiency co-treated with Folic Acid deficiency] results in increased expression of ADAM19 mRNA | CTD | PMID:20938992 | lead diacetate | decreases expression | ISO | RGD:735924 | 6480464 | lead acetate results in decreased expression of ADAM19 mRNA | CTD | PMID:22613225 | lipopolysaccharide | multiple interactions | ISO | RGD:735923 | 6480464 | [S-(1 more ... | CTD | PMID:35811015 | manganese(II) chloride | increases expression | EXP | | 6480464 | manganese chloride results in increased expression of ADAM19 mRNA | CTD | PMID:28801915 | menadione | decreases expression | ISO | RGD:735924 | 6480464 | Vitamin K 3 results in decreased expression of ADAM19 mRNA | CTD | PMID:25270620 | methyl methanesulfonate | decreases expression | ISO | RGD:735923 | 6480464 | Methyl Methanesulfonate results in decreased expression of ADAM19 mRNA | CTD | PMID:23649840 | N-Nitrosopyrrolidine | increases expression | ISO | RGD:735923 | 6480464 | N-Nitrosopyrrolidine results in increased expression of ADAM19 mRNA | CTD | PMID:32234424 | nickel atom | increases expression | ISO | RGD:735923 | 6480464 | Nickel results in increased expression of ADAM19 mRNA | CTD | PMID:25583101 | nickel sulfate | decreases expression | ISO | RGD:735924 | 6480464 | nickel sulfate results in decreased expression of ADAM19 mRNA | CTD | PMID:16166746 | nicotine | increases expression | ISO | RGD:735923 | 6480464 | Nicotine results in increased expression of ADAM19 mRNA | CTD | PMID:23825647 | O-methyleugenol | increases expression | ISO | RGD:735923 | 6480464 | methyleugenol results in increased expression of ADAM19 mRNA | CTD | PMID:32234424 | oxaliplatin | increases expression | ISO | RGD:735923 | 6480464 | oxaliplatin results in increased expression of ADAM19 mRNA | CTD | PMID:16510598 | ozone | multiple interactions | ISO | RGD:735924 | 6480464 | [Air Pollutants results in increased abundance of [Ozone co-treated with Soot]] which results in decreased expression of ADAM19 mRNA | CTD | PMID:34911549 | paracetamol | decreases expression | ISO | RGD:735923 | 6480464 | Acetaminophen results in decreased expression of ADAM19 mRNA | CTD | PMID:21420995 | paracetamol | decreases expression | EXP | | 6480464 | Acetaminophen results in decreased expression of ADAM19 mRNA | CTD | PMID:33387578 | PD 0325901 | decreases expression | ISO | RGD:735923 | 6480464 | mirdametinib results in decreased expression of ADAM19 mRNA | CTD | PMID:25119042 | PD 0325901 | multiple interactions | ISO | RGD:735923 | 6480464 | [(+)-JQ1 compound co-treated with mirdametinib] results in decreased expression of ADAM19 mRNA | CTD | PMID:25119042 | pentanal | increases expression | ISO | RGD:735923 | 6480464 | pentanal results in increased expression of ADAM19 mRNA | CTD | PMID:26079696 | pentane-2,3-dione | increases expression | EXP | | 6480464 | 2, 3-pentanedione results in increased expression of ADAM19 mRNA | CTD | PMID:25710175 | potassium chromate | decreases expression | ISO | RGD:735923 | 6480464 | potassium chromate(VI) results in decreased expression of ADAM19 mRNA | CTD | PMID:22079256 | potassium chromate | multiple interactions | ISO | RGD:735923 | 6480464 | [potassium chromate(VI) co-treated with epigallocatechin gallate] results in decreased expression of ADAM19 mRNA | CTD | PMID:22079256 | propanal | increases expression | ISO | RGD:735923 | 6480464 | propionaldehyde results in increased expression of ADAM19 mRNA | CTD | PMID:26079696 | raloxifene | multiple interactions | ISO | RGD:735923 | 6480464 | [Raloxifene Hydrochloride co-treated with ESR2 protein] results in increased expression of ADAM19 mRNA | CTD | PMID:19059307 | S-(1,2-dichlorovinyl)-L-cysteine | decreases expression | ISO | RGD:735923 | 6480464 | S-(1, 2-dichlorovinyl)cysteine results in decreased expression of ADAM19 mRNA | CTD | PMID:35811015 | S-(1,2-dichlorovinyl)-L-cysteine | multiple interactions | ISO | RGD:735923 | 6480464 | [S-(1 more ... | CTD | PMID:35811015 | sodium arsenate | decreases expression | ISO | RGD:735924 | 6480464 | sodium arsenate results in decreased expression of ADAM19 mRNA | CTD | PMID:21795629 | sodium arsenate | increases expression | ISO | RGD:735924 | 6480464 | sodium arsenate results in increased expression of ADAM19 mRNA | CTD | PMID:21795629 | sodium arsenite | affects methylation | ISO | RGD:735923 | 6480464 | sodium arsenite affects the methylation of ADAM19 gene | CTD | PMID:28589171 | sodium arsenite | decreases expression | ISO | RGD:735923 | 6480464 | sodium arsenite results in decreased expression of ADAM19 mRNA | CTD | PMID:34032870 | sodium arsenite | decreases expression | ISO | RGD:735924 | 6480464 | sodium arsenite results in decreased expression of ADAM19 mRNA | CTD | PMID:16014739 | sulforaphane | decreases expression | ISO | RGD:735924 | 6480464 | sulforaphane results in decreased expression of ADAM19 mRNA | CTD | PMID:30529165 | sulforaphane | multiple interactions | ISO | RGD:735924 | 6480464 | [NFE2L2 protein affects the susceptibility to sulforaphane] which affects the expression of ADAM19 mRNA | CTD | PMID:30529165 | sunitinib | decreases expression | ISO | RGD:735923 | 6480464 | Sunitinib results in decreased expression of ADAM19 mRNA | CTD | PMID:31533062 | tamoxifen | multiple interactions | ISO | RGD:735923 | 6480464 | [Tamoxifen co-treated with ESR2 protein] results in increased expression of ADAM19 mRNA | CTD | PMID:19059307 | temozolomide | increases expression | ISO | RGD:735923 | 6480464 | Temozolomide results in increased expression of ADAM19 mRNA | CTD | PMID:31758290 | tert-butyl hydroperoxide | increases expression | ISO | RGD:735923 | 6480464 | tert-Butylhydroperoxide results in increased expression of ADAM19 mRNA | CTD | PMID:15336504 | testosterone | increases expression | ISO | RGD:735923 | 6480464 | Testosterone results in increased expression of ADAM19 mRNA | CTD | PMID:33359661, PMID:34719554 | tetrachloromethane | increases expression | ISO | RGD:735924 | 6480464 | Carbon Tetrachloride results in increased expression of ADAM19 mRNA | CTD | PMID:17484886 | thioacetamide | increases expression | EXP | | 6480464 | Thioacetamide results in increased expression of ADAM19 mRNA | CTD | PMID:34492290 | titanium dioxide | increases expression | EXP | | 6480464 | titanium dioxide results in increased expression of ADAM19 mRNA | CTD | PMID:30012374 | toluene | increases methylation | ISO | RGD:735923 | 6480464 | Toluene results in increased methylation of ADAM19 gene | CTD | PMID:26717081 | toluene | decreases expression | ISO | RGD:735923 | 6480464 | Toluene results in decreased expression of ADAM19 mRNA | CTD | PMID:26717081 | Tributyltin oxide | increases expression | ISO | RGD:735924 | 6480464 | bis(tri-n-butyltin)oxide results in increased expression of ADAM19 mRNA | CTD | PMID:18958704 | trimellitic anhydride | increases expression | ISO | RGD:735924 | 6480464 | trimellitic anhydride results in increased expression of ADAM19 mRNA | CTD | PMID:19042947 | tris(2-butoxyethyl) phosphate | affects expression | ISO | RGD:735923 | 6480464 | tris(2-butoxyethyl) phosphate affects the expression of ADAM19 mRNA | CTD | PMID:29024780 | tungsten | decreases expression | ISO | RGD:735924 | 6480464 | Tungsten results in decreased expression of ADAM19 mRNA | CTD | PMID:30912803 | valproic acid | decreases expression | ISO | RGD:735923 | 6480464 | Valproic Acid results in decreased expression of ADAM19 mRNA | CTD | PMID:29154799 | valproic acid | increases expression | ISO | RGD:735923 | 6480464 | Valproic Acid results in increased expression of ADAM19 mRNA | CTD | PMID:23179753, PMID:28001369 | valproic acid | increases methylation | ISO | RGD:735923 | 6480464 | Valproic Acid results in increased methylation of ADAM19 gene | CTD | PMID:29154799 | zinc atom | increases expression | ISO | RGD:735923 | 6480464 | Zinc deficiency results in increased expression of ADAM19 mRNA | CTD | PMID:22171008 | zinc(0) | increases expression | ISO | RGD:735923 | 6480464 | Zinc deficiency results in increased expression of ADAM19 mRNA | CTD | PMID:22171008 | zoledronic acid | decreases expression | ISO | RGD:735923 | 6480464 | zoledronic acid results in decreased expression of ADAM19 mRNA | CTD | PMID:24714768 | |