Gene: Tnk1 (tyrosine kinase, non-receptor, 1) Rattus norvegicus
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Symbol: Tnk1
Name: tyrosine kinase, non-receptor, 1
Description: ENCODES a protein that exhibits ATP binding (ortholog); non-membrane spanning protein tyrosine kinase activity (ortholog); protein tyrosine kinase activity (ortholog); INVOLVED IN negative regulation of cell growth (ortholog); negative regulation of Ras protein signal transduction (ortholog); protein autophosphorylation (ortholog); ASSOCIATED WITH Weissenbacher-Zweymuller syndrome (ortholog); FOUND IN cytoplasm (ortholog); cytosol (ortholog); membrane (ortholog); INTERACTS WITH bisphenol A; orphenadrine; thioacetamide
AGR Description: Predicted to have ATP binding activity and non-membrane spanning protein tyrosine kinase activity; predicted to be involved in several processes, including cell differentiation, negative regulation of Ras protein signal transduction, and negative regulation of cell growth; predicted to localize to the cytosol and membrane; orthologous to human TNK1 (tyrosine kinase non receptor 1).
Merged Description: Predicted to have ATP binding activity and non-membrane spanning protein tyrosine kinase activity; predicted to be involved in several processes, including cell differentiation, negative regulation of Ras protein signal transduction, and negative regulation of cell growth; predicted to localize to the cytosol and membrane; orthologous to human TNK1 (tyrosine kinase non receptor 1); INTERACTS WITH bisphenol A; orphenadrine; thioacetamide.
Type: protein-coding
RefSeq Status: PROVISIONAL
Also known as: LOC303247; non-receptor tyrosine-protein kinase TNK1
Orthologs:
Homo sapiens (human) : TNK1 (tyrosine kinase non receptor 1)  HGNC  Alliance
Mus musculus (house mouse) : Tnk1 (tyrosine kinase, non-receptor, 1)  MGI  Alliance
Chinchilla lanigera (long-tailed chinchilla) : Tnk1 (tyrosine kinase non receptor 1)
Pan paniscus (bonobo/pygmy chimpanzee) : TNK1 (tyrosine kinase non receptor 1)
Canis lupus familiaris (dog) : TNK1 (tyrosine kinase non receptor 1)
Ictidomys tridecemlineatus (thirteen-lined ground squirrel) : Tnk1 (tyrosine kinase non receptor 1)
Sus scrofa (pig) : TNK1 (tyrosine kinase non receptor 1)
more info ...
Latest Assembly: Rnor_6.0 - RGSC Genome Assembly v6.0
Position:
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Rnor_6.01056,458,650 - 56,475,183 (-)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_5.01056,203,769 - 56,212,284 (-)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.41056,692,319 - 56,698,602 (-)NCBIRGSC3.4rn4RGSC3.4
RGSC_v3.11056,705,941 - 56,714,918 (-)NCBI
Celera1053,726,241 - 53,732,527 (-)NCBICelera
Cytogenetic Map10q24NCBI
JBrowse: View Region in Genome Browser (JBrowse)
Model


Disease Annotations
Gene-Chemical Interaction Annotations
Gene Ontology Annotations
References - curated
References - uncurated
RGD Disease Portals

Genomics

Comparative Map Data
QTLs in Region (Rnor_6.0)
miRNA Target Status

Sequence

Nucleotide Sequences
Protein Sequences
Transcriptome

Strain Variation

Strain Sequence Variants (Rnor 5.0)
Damaging Variants

Additional Information

External Database Links
Nomenclature History
 
More on Tnk1
Alliance Gene
NCBI Gene
Ensembl Gene
JBrowse: rn5 rn6
NCBI Genome Data Viewer

RGD Object Information
RGD ID: 1310113
Created: 2005-01-12
Species: Rattus norvegicus
Last Modified: 2019-04-12
Status: ACTIVE



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RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.