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Gene: Il13 (interleukin 13) Rattus norvegicus
Symbol: Il13
Name: interleukin 13
Description: Exhibits interleukin-13 receptor binding activity. Involved in several processes, including positive regulation of cell population proliferation; positive regulation of macromolecule metabolic process; and regulation of cation transmembrane transport. Localizes to extracellular space. Used to study asthma; extrinsic allergic alveolitis; and lipoid nephrosis. Biomarker of several diseases, including alcoholic hepatitis; middle cerebral artery infarction; peptic esophagitis; prostatic hypertrophy; and pulmonary hypertension. Human ortholog(s) of this gene implicated in several diseases, including allergic hypersensitivity disease (multiple); autoimmune hypersensitivity disease (multiple); dermatitis (multiple); lung disease (multiple); and nose disease (multiple). Orthologous to human IL13 (interleukin 13); PARTICIPATES IN Fc epsilon receptor mediated signaling pathway; asthma pathway; cytokine mediated signaling pathway; INTERACTS WITH 3-chloropropane-1,2-diol; acrylamide; ammonium chloride.
Type: protein-coding
Also known as: IL-13; interleukin-13; T-cell activation protein P600
Homo sapiens (human) : IL13 (interleukin 13)  HGNC  Alliance
Mus musculus (house mouse) : Il13 (interleukin 13)  MGI  Alliance
Chinchilla lanigera (long-tailed chinchilla) : Il13 (interleukin 13)
Pan paniscus (bonobo/pygmy chimpanzee) : IL13 (interleukin 13)
Canis lupus familiaris (dog) : IL13 (interleukin 13)
Ictidomys tridecemlineatus (thirteen-lined ground squirrel) : Il13 (interleukin 13)
Sus scrofa (pig) : IL13 (interleukin 13)
Chlorocebus sabaeus (African green monkey) : IL13 (interleukin 13)
Heterocephalus glaber (naked mole-rat) : Il13 (interleukin 13)
more info ...
Latest Assembly: Rnor_6.0 - RGSC Genome Assembly v6.0
Rat AssemblyChrPosition (strand)SourceGenome Browsers
Rnor_6.01038,982,909 - 38,985,466 (-)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl1038,982,909 - 38,985,466 (-)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.01038,764,639 - 38,767,196 (-)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.41039,093,512 - 39,096,069 (-)NCBIRGSC3.4rn4RGSC3.4
RGSC_v3.11039,102,758 - 39,105,316 (-)NCBI
Celera1037,134,342 - 37,136,897 (-)NCBICelera
Cytogenetic Map10q22NCBI
JBrowse: View Region in Genome Browser (JBrowse)

Disease Annotations
Gene-Chemical Interaction Annotations
Gene Ontology Annotations
Molecular Pathway Annotations
References - curated
References - uncurated


Comparative Map Data
QTLs in Region (Rnor_6.0)
miRNA Target Status


RNA-SEQ Expression


Nucleotide Sequences
Protein Sequences

Strain Variation

Strain Sequence Variants (Rnor 6.0)

Additional Information

External Database Links
Nomenclature History
RGD Curation Notes
More on Il13
Alliance Gene
Ensembl Gene
JBrowse: rn5 rn6
NCBI Genome Data Viewer

RGD Object Information
RGD ID: 68949
Created: 2001-11-06
Species: Rattus norvegicus
Last Modified: 2020-05-05
Status: ACTIVE


RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.