Dhrs7b (dehydrogenase/reductase 7B) - Rat Genome Database

Send us a Message



Submit Data |  Help |  Video Tutorials |  News |  Publications |  Download |  REST API |  Citing RGD |  Contact   
Gene: Dhrs7b (dehydrogenase/reductase 7B) Rattus norvegicus
Analyze
Symbol: Dhrs7b
Name: dehydrogenase/reductase 7B
RGD ID: 1311243
Description: Predicted to enable DNA-binding transcription factor binding activity and transcription corepressor activity. Predicted to be involved in ether lipid biosynthetic process and neutrophil differentiation. Predicted to act upstream of or within several processes, including brown fat cell differentiation; phosphatidylcholine biosynthetic process; and regulation of cold-induced thermogenesis. Predicted to be located in nucleus and peroxisome. Predicted to be part of transcription regulator complex. Predicted to be active in membrane. Orthologous to human DHRS7B (dehydrogenase/reductase 7B); INTERACTS WITH 3-chloropropane-1,2-diol; 5-methoxy-2-\{[(4-methoxy-3,5-dimethylpyridin-2-yl)methyl]sulfinyl\}-1H-benzimidazole; 6-propyl-2-thiouracil.
Type: protein-coding
RefSeq Status: PROVISIONAL
Previously known as: dehydrogenase/reductase (SDR family) member 7B; dehydrogenase/reductase SDR family member 7B; LOC287380; MGC105547; RGD1311243; SDR family dehydrogenase/reductase member 7B; short-chain dehydrogenase/reductase family 32C member 1; similar to DKFZP566O084 protein
RGD Orthologs
Human
Mouse
Chinchilla
Bonobo
Dog
Squirrel
Pig
Green Monkey
Naked Mole-Rat
Alliance Genes
More Info more info ...
Latest Assembly: mRatBN7.2 - mRatBN7.2 Assembly
Position:
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr81046,003,845 - 46,036,498 (+)NCBIGRCr8
mRatBN7.21045,504,344 - 45,537,094 (+)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl1045,504,426 - 45,537,076 (+)EnsemblmRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx1050,205,760 - 50,239,151 (+)NCBIRnor_SHRUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.01049,696,146 - 49,729,535 (+)NCBIRnor_SHRSPUTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.01045,199,735 - 45,233,124 (+)NCBIRnor_WKYUTH_Rnor_WKY_Bbb_1.0
Rnor_6.01047,065,755 - 47,111,089 (+)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl1047,065,850 - 47,111,101 (+)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.01046,837,592 - 46,884,565 (+)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.41046,971,430 - 47,003,953 (+)NCBIRGSC3.4RGSC_v3.4rn4RGSC3.4
RGSC_v3.11046,985,052 - 47,017,575 (+)NCBI
Celera1044,758,979 - 44,791,995 (+)NCBICelera
Cytogenetic Map10q22NCBI
JBrowse: View Region in Genome Browser (JBrowse)
Model


Disease Annotations     Click to see Annotation Detail View

Gene Ontology Annotations     Click to see Annotation Detail View

Cellular Component

Molecular Function

References

References - curated
# Reference Title Reference Citation
1. Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium. Gaudet P, etal., Brief Bioinform. 2011 Sep;12(5):449-62. doi: 10.1093/bib/bbr042. Epub 2011 Aug 27.
2. GOA pipeline RGD automated data pipeline
3. Data Import for Chemical-Gene Interactions RGD automated import pipeline for gene-chemical interactions
Additional References at PubMed
PMID:12477932   PMID:17522052   PMID:18775470   PMID:19946888   PMID:22871113   PMID:25565205  


Genomics

Comparative Map Data
Dhrs7b
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr81046,003,845 - 46,036,498 (+)NCBIGRCr8
mRatBN7.21045,504,344 - 45,537,094 (+)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl1045,504,426 - 45,537,076 (+)EnsemblmRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx1050,205,760 - 50,239,151 (+)NCBIRnor_SHRUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.01049,696,146 - 49,729,535 (+)NCBIRnor_SHRSPUTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.01045,199,735 - 45,233,124 (+)NCBIRnor_WKYUTH_Rnor_WKY_Bbb_1.0
Rnor_6.01047,065,755 - 47,111,089 (+)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl1047,065,850 - 47,111,101 (+)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.01046,837,592 - 46,884,565 (+)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.41046,971,430 - 47,003,953 (+)NCBIRGSC3.4RGSC_v3.4rn4RGSC3.4
RGSC_v3.11046,985,052 - 47,017,575 (+)NCBI
Celera1044,758,979 - 44,791,995 (+)NCBICelera
Cytogenetic Map10q22NCBI
DHRS7B
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh381721,126,964 - 21,191,420 (+)NCBIGRCh38GRCh38hg38GRCh38
GRCh38.p14 Ensembl1721,123,364 - 21,193,265 (+)EnsemblGRCh38hg38GRCh38
GRCh371721,030,277 - 21,094,733 (+)NCBIGRCh37GRCh37hg19GRCh37
Build 361720,970,850 - 21,035,428 (+)NCBINCBI36Build 36hg18NCBI36
Celera1721,447,631 - 21,512,215 (-)NCBICelera
Cytogenetic Map17p11.2NCBI
HuRef1720,232,340 - 20,297,454 (+)NCBIHuRef
CHM1_11721,039,829 - 21,104,899 (+)NCBICHM1_1
T2T-CHM13v2.01721,068,745 - 21,140,297 (+)NCBIT2T-CHM13v2.0
Dhrs7b
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm391160,721,457 - 60,749,249 (+)NCBIGRCm39GRCm39mm39
GRCm39 Ensembl1160,721,457 - 60,751,021 (+)EnsemblGRCm39 Ensembl
GRCm381160,830,631 - 60,858,423 (+)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl1160,830,631 - 60,860,195 (+)EnsemblGRCm38mm10GRCm38
MGSCv371160,644,133 - 60,671,925 (+)NCBIGRCm37MGSCv37mm9NCBIm37
MGSCv361160,646,883 - 60,674,341 (+)NCBIMGSCv36mm8
Celera1167,825,089 - 67,834,528 (-)NCBICelera
Cytogenetic Map11B2NCBI
cM Map1137.87NCBI
Dhrs7b
(Chinchilla lanigera - long-tailed chinchilla)
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0 EnsemblNW_0049555771,071,775 - 1,121,940 (+)EnsemblChiLan1.0
ChiLan1.0NW_0049555771,071,904 - 1,122,204 (+)NCBIChiLan1.0ChiLan1.0
DHRS7B
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
NHGRI_mPanPan1-v21950,196,297 - 50,264,246 (-)NCBINHGRI_mPanPan1-v2
NHGRI_mPanPan11755,064,419 - 55,132,964 (-)NCBINHGRI_mPanPan1
Mhudiblu_PPA_v01730,455,933 - 30,520,997 (-)NCBIMhudiblu_PPA_v0Mhudiblu_PPA_v0panPan3
PanPan1.11735,319,039 - 35,387,106 (-)NCBIpanpan1.1PanPan1.1panPan2
PanPan1.1 Ensembl1735,317,600 - 35,383,619 (-)Ensemblpanpan1.1panPan2
DHRS7B
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.1542,603,027 - 42,666,446 (+)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
CanFam3.1 Ensembl542,603,078 - 42,665,673 (+)EnsemblCanFam3.1canFam3CanFam3.1
Dog10K_Boxer_Tasha542,741,213 - 42,804,652 (+)NCBIDog10K_Boxer_Tasha
ROS_Cfam_1.0542,710,747 - 42,774,163 (+)NCBIROS_Cfam_1.0
UMICH_Zoey_3.1542,677,287 - 42,740,753 (+)NCBIUMICH_Zoey_3.1
UNSW_CanFamBas_1.0542,624,428 - 42,687,843 (+)NCBIUNSW_CanFamBas_1.0
UU_Cfam_GSD_1.0542,817,219 - 42,880,678 (+)NCBIUU_Cfam_GSD_1.0
Dhrs7b
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HiC_Itri_2NW_02440560262,371,158 - 62,412,067 (+)NCBIHiC_Itri_2
SpeTri2.0 EnsemblNW_004936741456,465 - 496,121 (-)EnsemblSpeTri2.0SpeTri2.0 Ensembl
SpeTri2.0NW_004936741455,796 - 496,089 (-)NCBISpeTri2.0SpeTri2.0SpeTri2.0
DHRS7B
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 Ensembl1261,320,730 - 61,350,219 (+)EnsemblSscrofa11.1susScr11Sscrofa11.1
Sscrofa11.11261,320,665 - 61,347,542 (+)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
DHRS7B
(Chlorocebus sabaeus - green monkey)
Green Monkey AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.11619,238,397 - 19,301,307 (+)NCBIChlSab1.1ChlSab1.1chlSab2
ChlSab1.1 Ensembl1619,284,743 - 19,301,144 (+)EnsemblChlSab1.1ChlSab1.1 EnsemblchlSab2
Vero_WHO_p1.0NW_0236660591,456,570 - 1,520,627 (-)NCBIVero_WHO_p1.0Vero_WHO_p1.0
Dhrs7b
(Heterocephalus glaber - naked mole-rat)
Naked Mole-Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla_female_1.0 EnsemblNW_0046248494,858,517 - 4,903,686 (+)EnsemblHetGla_female_1.0HetGla_female_1.0 EnsemblhetGla2
HetGla 1.0NW_0046248494,858,496 - 4,905,157 (+)NCBIHetGla_female_1.0HetGla 1.0hetGla2

Variants

.
Variants in Dhrs7b
173 total Variants
miRNA Target Status

Predicted Target Of
Summary Value
Count of predictions:265
Count of miRNA genes:152
Interacting mature miRNAs:171
Transcripts:ENSRNOT00000065294, ENSRNOT00000066250
Prediction methods:Microtar, Miranda, Rnahybrid, Targetscan
Result types:miRGate_prediction

The detailed report is available here: Full Report CSV TAB Printer

miRNA Target Status data imported from miRGate (http://mirgate.bioinfo.cnio.es/).
For more information about miRGate, see PMID:25858286 or access the full paper here.


QTLs in Region (mRatBN7.2)
The following QTLs overlap with this region.    Full Report CSV TAB Printer Gviewer
RGD IDSymbolNameLODP ValueTraitSub TraitChrStartStopSpecies
70223Bp57Blood pressure QTL 575arterial blood pressure trait (VT:2000000)systolic blood pressure (CMO:0000004)10180676123Rat
631554Bp133Blood pressure QTL 1330.005arterial blood pressure trait (VT:2000000)systolic blood pressure (CMO:0000004)1074336463851208Rat
2313064Bmd71Bone mineral density QTL 710.90.0001tibia mineral mass (VT:1000283)compact volumetric bone mineral density (CMO:0001730)10538701450387014Rat
2313066Bss63Bone structure and strength QTL 631.40.0001tibia strength trait (VT:1000284)bone polar moment of inertia (CMO:0001558)10538701450387014Rat
2313081Bss64Bone structure and strength QTL 641.30.0001tibia strength trait (VT:1000284)tibia total energy absorbed before break (CMO:0001736)10538701450387014Rat
2313095Bss62Bone structure and strength QTL 621.50.0001tibia size trait (VT:0100001)tibia midshaft cross-sectional area (CMO:0001717)10538701450387014Rat
2313104Bss61Bone structure and strength QTL 610.90.0001tibia area (VT:1000281)tibia midshaft cross-sectional area (CMO:0001717)10538701450387014Rat
2298544Neuinf9Neuroinflammation QTL 94.6nervous system integrity trait (VT:0010566)spinal cord complement component 1, q subcomponent, B chain mRNA level (CMO:0002126)10580199062146030Rat
8662860Vetf10Vascular elastic tissue fragility QTL 10artery integrity trait (VT:0010639)number of ruptures of the internal elastic lamina of the abdominal aorta and iliac arteries (CMO:0002562)10615418273453136Rat
61427Cia16Collagen induced arthritis QTL 163.2joint integrity trait (VT:0010548)joint inflammation composite score (CMO:0000919)10635789696121100Rat
1578761Stresp21Stress response QTL 213.3thymus mass (VT:0004954)thymus wet weight (CMO:0000855)10637574651375746Rat
2303118Mamtr7Mammary tumor resistance QTL 70.003mammary gland integrity trait (VT:0010552)mammary tumor growth rate (CMO:0000344)109658275104670812Rat
9590310Scort19Serum corticosterone level QTL 196.30.001blood corticosterone amount (VT:0005345)plasma corticosterone level (CMO:0001173)101147401056474010Rat
9590268Scort13Serum corticosterone level QTL 133.260.001blood corticosterone amount (VT:0005345)plasma corticosterone level (CMO:0001173)101147401056474010Rat
9589136Insul27Insulin level QTL 2710.460.001blood insulin amount (VT:0001560)plasma insulin level (CMO:0000342)101147401056474010Rat
2301967Cm73Cardiac mass QTL 734.55heart left ventricle mass (VT:0007031)heart left ventricle weight to body weight ratio (CMO:0000530)101448701189062041Rat
631268Cia21Collagen induced arthritis QTL 213.1joint integrity trait (VT:0010548)joint inflammation composite score (CMO:0000919)1014487011104060283Rat
2316949Gluco60Glucose level QTL 603.7blood glucose amount (VT:0000188)blood glucose level (CMO:0000046)1014487011107057807Rat
1354587Kidm21Kidney mass QTL 213.3kidney mass (VT:0002707)right kidney wet weight (CMO:0000082)101502851360430477Rat
631564Apr3Acute phase response QTL 33.9blood interleukin-6 amount (VT:0008595)plasma interleukin-6 level (CMO:0001927)101527595560275955Rat
6893350Bw99Body weight QTL 990.870.16body mass (VT:0001259)body weight (CMO:0000012)11590666560906665Rat
6893352Bw100Body weight QTL 1000.330.6body mass (VT:0001259)body weight (CMO:0000012)11590666560906665Rat
631532Cm50Cardiac mass QTL 506.6heart mass (VT:0007028)calculated heart weight (CMO:0000073)101790711351786432Rat
1598852Anxrr19Anxiety related response QTL 195.07body movement coordination trait (VT:0005424)number of rearing movements in an experimental apparatus (CMO:0001752)101816784163167841Rat
2313055Bw96Body weight QTL 963.60.0001body mass (VT:0001259)body weight (CMO:0000012)101960648364606483Rat
2313087Bmd80Bone mineral density QTL 803.20.0001tibia mineral mass (VT:1000283)total volumetric bone mineral density (CMO:0001728)101960648364606483Rat
1554317Bmd4Bone mineral density QTL 49.40.0001lumbar vertebra mineral mass (VT:0010511)volumetric bone mineral density (CMO:0001553)101981604299406971Rat
1581497Esta1Estrogen-induced thymic atrophy QTL 1thymus mass (VT:0004954)thymus wet weight (CMO:0000855)102132980561345413Rat
724556Pur2Proteinuria QTL 25.5urine protein amount (VT:0005160)urine protein level (CMO:0000591)102242750090627625Rat
61354Pia10Pristane induced arthritis QTL 100.01joint integrity trait (VT:0010548)joint inflammation composite score (CMO:0000919)1023444813104060283Rat
631267Cia20Collagen induced arthritis QTL 203.2joint integrity trait (VT:0010548)joint inflammation composite score (CMO:0000919)1023444813104060283Rat
61325Aia5Adjuvant induced arthritis QTL 50.01joint integrity trait (VT:0010548)joint inflammation composite score (CMO:0000919)1023444813104060283Rat
70224Eae3Experimental allergic encephalomyelitis QTL 34.1nervous system integrity trait (VT:0010566)experimental autoimmune encephalomyelitis incidence/prevalence measurement (CMO:0001046)102652195761345413Rat
1298069Bp168Blood pressure QTL 1685.5blood pressure trait (VT:0000183)systolic blood pressure (CMO:0000004)102652195798003205Rat
631542Bp82Blood pressure QTL 826.8arterial blood pressure trait (VT:2000000)systolic blood pressure (CMO:0000004)102652195798952741Rat
2300171Bmd58Bone mineral density QTL 584.90.0001lumbar vertebra mineral mass (VT:0010511)volumetric bone mineral density (CMO:0001553)102694462871944628Rat
10402859Bp381Blood pressure QTL 3810.002arterial blood pressure trait (VT:2000000)mean arterial blood pressure (CMO:0000009)102760646872606468Rat
2292441Bp308Blood pressure QTL 308arterial blood pressure trait (VT:2000000)mean arterial blood pressure (CMO:0000009)102760646872606468Rat
724527Bp148Blood pressure QTL 1480.0001arterial blood pressure trait (VT:2000000)mean arterial blood pressure (CMO:0000009)102845313673453136Rat
1600371Mcs21Mammary carcinoma susceptibility QTL 213mammary gland integrity trait (VT:0010552)mammary tumor growth rate (CMO:0000344)102887565052200160Rat
1331762Rf40Renal function QTL 403.873kidney blood vessel physiology trait (VT:0100012)absolute change in renal vascular resistance (CMO:0001900)102929950464155584Rat
1331791Cm31Cardiac mass QTL 313.84606heart mass (VT:0007028)heart wet weight (CMO:0000069)1029299504107211142Rat
631557Bp136Blood pressure QTL 1360.003arterial blood pressure trait (VT:2000000)systolic blood pressure (CMO:0000004)103063205375632053Rat
1576311Pia26Pristane induced arthritis QTL 26joint integrity trait (VT:0010548)joint inflammation composite score (CMO:0000919)103122402675632053Rat
1578779Tcas10Tongue tumor susceptibility QTL 103.12tongue integrity trait (VT:0010553)number of squamous cell tumors of the tongue with diameter greater than 3 mm (CMO:0001950)103129743976297439Rat
1576319Cia29Collagen induced arthritis QTL 29joint integrity trait (VT:0010548)joint inflammation composite score (CMO:0000919)103397392178973921Rat
61332Eau3Experimental allergic uveoretinitis QTL 30.004uvea integrity trait (VT:0010551)experimental autoimmune uveitis score (CMO:0001504)103449055945579777Rat
1354614Hpcl1Hepatic cholesterol level QTL 13.3liver cholesterol amount (VT:0010498)liver cholesterol level (CMO:0001597)103539226751793994Rat
1358897Stresp6Stress response QTL 64.170.022blood norepinephrine amount (VT:0005663)plasma norepinephrine level (CMO:0001010)103539226764155584Rat
61441Btemp1Thermal response to stress QTL 14body temperature trait (VT:0005535)core body temperature (CMO:0001036)103539245763642539Rat
2317042Aia20Adjuvant induced arthritis QTL 203.38joint integrity trait (VT:0010548)right rear ankle joint diameter (CMO:0002150)103756507982565079Rat
2317043Aia7Adjuvant induced arthritis QTL 73.82joint integrity trait (VT:0010548)left rear ankle joint diameter (CMO:0002149)103756507982565079Rat
1576308Schws1Schwannoma susceptibility QTL 10.0041nervous system integrity trait (VT:0010566)percentage of study population developing trigeminal nerve neurilemmomas during a period of time (CMO:0002017)1040035094102359817Rat
631269Cia22Collagen induced arthritis QTL 228.9joint integrity trait (VT:0010548)joint inflammation composite score (CMO:0000919)1040035094104060283Rat
631270Cia23Collagen induced arthritis QTL 233.9joint integrity trait (VT:0010548)joint inflammation composite score (CMO:0000919)1040035094104060283Rat
631552Vetf2Vascular elastic tissue fragility QTL 24.50.0002aorta elastic tissue integrity trait (VT:0010556)artery internal elastic lamina non-tumorous lesion count (CMO:0001913)104114263386142633Rat
61463Bp12Blood pressure QTL 126.30.0001arterial blood pressure trait (VT:2000000)systolic blood pressure (CMO:0000004)104133325886333258Rat
8552805Bw145Body weight QTL 1452.2body mass (VT:0001259)change in body weight to body weight ratio (CMO:0002216)104194452678307017Rat
1298078Stresp5Stress response QTL 52.990.00025blood corticosterone amount (VT:0005345)plasma corticosterone level (CMO:0001173)1042045676104670812Rat
70188BpQTLcluster1Blood pressure QTL cluster 14.864arterial blood pressure trait (VT:2000000)diastolic blood pressure (CMO:0000005)14232313287323132Rat
70188BpQTLcluster1Blood pressure QTL cluster 14.864arterial blood pressure trait (VT:2000000)systolic blood pressure (CMO:0000004)14232313287323132Rat
70188BpQTLcluster1Blood pressure QTL cluster 14.864arterial blood pressure trait (VT:2000000)mean arterial blood pressure (CMO:0000009)14232313287323132Rat
70188BpQTLcluster1Blood pressure QTL cluster 14.864arterial blood pressure trait (VT:2000000)pulse pressure (CMO:0000292)14232313287323132Rat
70198BpQTLcluster9Blood pressure QTL cluster 92.94arterial blood pressure trait (VT:2000000)mean arterial blood pressure (CMO:0000009)104232313287323132Rat
6893342Cm78Cardiac mass QTL 780.10.88heart mass (VT:0007028)heart weight to body weight ratio (CMO:0000074)104287676679813922Rat
9589030Epfw9Epididymal fat weight QTL 919.240.001epididymal fat pad mass (VT:0010421)epididymal fat pad weight to body weight ratio (CMO:0000658)104444169989441699Rat
7411614Foco18Food consumption QTL 180.001eating behavior trait (VT:0001431)feed conversion ratio (CMO:0001312)104444169989441699Rat
8694173Bw149Body weight QTL 1494.380.001body mass (VT:0001259)body weight gain (CMO:0000420)104444169989441699Rat
2300218Hpcl2Hepatic cholesterol level QTL 2liver cholesterol amount (VT:0010498)liver cholesterol level (CMO:0001597)104502965095600334Rat

Markers in Region
RH129793  
Rat AssemblyChrPosition (strand)SourceJBrowse
mRatBN7.21045,536,796 - 45,536,977 (+)MAPPERmRatBN7.2
Rnor_6.01047,110,884 - 47,111,064NCBIRnor6.0
Rnor_5.01046,884,360 - 46,884,540UniSTSRnor5.0
RGSC_v3.41047,003,754 - 47,003,934UniSTSRGSC3.4
Celera1044,791,796 - 44,791,976UniSTS
RH 3.4 Map10525.19UniSTS
Cytogenetic Map10q22UniSTS
RH142607  
Rat AssemblyChrPosition (strand)SourceJBrowse
mRatBN7.21045,533,036 - 45,533,209 (+)MAPPERmRatBN7.2
Rnor_6.01047,107,124 - 47,107,296NCBIRnor6.0
Rnor_5.01046,880,600 - 46,880,772UniSTSRnor5.0
RGSC_v3.41046,999,994 - 47,000,166UniSTSRGSC3.4
Celera1044,788,036 - 44,788,208UniSTS
RH 3.4 Map10497.8UniSTS
Cytogenetic Map10q22UniSTS
BF386674  
Rat AssemblyChrPosition (strand)SourceJBrowse
mRatBN7.21045,523,003 - 45,523,173 (+)MAPPERmRatBN7.2
Rnor_6.01047,096,771 - 47,096,940NCBIRnor6.0
Rnor_5.01046,870,247 - 46,870,416UniSTSRnor5.0
RGSC_v3.41046,989,965 - 46,990,134UniSTSRGSC3.4
Celera1044,777,995 - 44,778,164UniSTS
RH 3.4 Map10529.78UniSTS
Cytogenetic Map10q22UniSTS


Expression


RNA-SEQ Expression
High: > 1000 TPM value   Medium: Between 11 and 1000 TPM
Low: Between 0.5 and 10 TPM   Below Cutoff: < 0.5 TPM

alimentary part of gastrointestinal system circulatory system endocrine system exocrine system hemolymphoid system hepatobiliary system integumental system musculoskeletal system nervous system renal system reproductive system respiratory system appendage
High
Medium 3 38 57 41 19 41 4 7 74 35 41 11 4
Low 5 4 4 4
Below cutoff

Sequence


RefSeq Acc Id: ENSRNOT00000065294   ⟹   ENSRNOP00000063744
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.2 Ensembl1045,504,441 - 45,537,076 (+)Ensembl
Rnor_6.0 Ensembl1047,081,834 - 47,111,101 (+)Ensembl
RefSeq Acc Id: ENSRNOT00000066250   ⟹   ENSRNOP00000063346
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.2 Ensembl1045,504,426 - 45,536,996 (+)Ensembl
Rnor_6.0 Ensembl1047,065,863 - 47,111,082 (+)Ensembl
RefSeq Acc Id: ENSRNOT00000077868   ⟹   ENSRNOP00000071925
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.2 Ensembl1045,521,496 - 45,536,996 (+)Ensembl
Rnor_6.0 Ensembl1047,065,850 - 47,110,858 (+)Ensembl
RefSeq Acc Id: NM_001008507   ⟹   NP_001008507
RefSeq Status: PROVISIONAL
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr81046,003,973 - 46,036,498 (+)NCBI
mRatBN7.21045,504,469 - 45,536,996 (+)NCBI
Rnor_6.01047,065,863 - 47,111,083 (+)NCBI
Rnor_5.01046,837,592 - 46,884,565 (+)NCBI
RGSC_v3.41046,971,430 - 47,003,953 (+)RGD
Celera1044,758,979 - 44,791,995 (+)RGD
Sequence:
RefSeq Acc Id: XM_006246472   ⟹   XP_006246534
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr81046,003,936 - 46,036,498 (+)NCBI
mRatBN7.21045,504,363 - 45,537,093 (+)NCBI
Rnor_6.01047,065,755 - 47,111,089 (+)NCBI
Rnor_5.01046,837,592 - 46,884,565 (+)NCBI
Sequence:
RefSeq Acc Id: XM_006246473   ⟹   XP_006246535
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr81046,013,103 - 46,036,498 (+)NCBI
mRatBN7.21045,513,599 - 45,537,093 (+)NCBI
Rnor_6.01047,065,755 - 47,111,089 (+)NCBI
Rnor_5.01046,837,592 - 46,884,565 (+)NCBI
Sequence:
RefSeq Acc Id: XM_039085405   ⟹   XP_038941333
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr81046,003,856 - 46,036,498 (+)NCBI
mRatBN7.21045,504,348 - 45,537,093 (+)NCBI
RefSeq Acc Id: XM_039085406   ⟹   XP_038941334
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr81046,003,868 - 46,036,498 (+)NCBI
mRatBN7.21045,504,355 - 45,537,093 (+)NCBI
RefSeq Acc Id: XM_039085407   ⟹   XP_038941335
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr81046,003,845 - 46,036,061 (+)NCBI
mRatBN7.21045,504,344 - 45,537,094 (+)NCBI
RefSeq Acc Id: XM_039085409   ⟹   XP_038941337
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr81046,003,846 - 46,036,498 (+)NCBI
mRatBN7.21045,504,344 - 45,537,093 (+)NCBI
RefSeq Acc Id: XM_063268623   ⟹   XP_063124693
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr81046,007,447 - 46,036,498 (+)NCBI
RefSeq Acc Id: NP_001008507   ⟸   NM_001008507
- UniProtKB: A4GWE3 (UniProtKB/Swiss-Prot),   Q5RJY4 (UniProtKB/Swiss-Prot),   A6HF59 (UniProtKB/TrEMBL),   A0A8L2R5J7 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: XP_006246534   ⟸   XM_006246472
- Peptide Label: isoform X1
- UniProtKB: A6HF61 (UniProtKB/TrEMBL),   A0A8L2QVC0 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: XP_006246535   ⟸   XM_006246473
- Peptide Label: isoform X1
- UniProtKB: A6HF61 (UniProtKB/TrEMBL),   A0A8L2QVC0 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: ENSRNOP00000063744   ⟸   ENSRNOT00000065294
RefSeq Acc Id: ENSRNOP00000071925   ⟸   ENSRNOT00000077868
RefSeq Acc Id: ENSRNOP00000063346   ⟸   ENSRNOT00000066250
RefSeq Acc Id: XP_038941335   ⟸   XM_039085407
- Peptide Label: isoform X2
- UniProtKB: A6HF60 (UniProtKB/TrEMBL)
RefSeq Acc Id: XP_038941337   ⟸   XM_039085409
- Peptide Label: isoform X3
- UniProtKB: A0A8L2R5J7 (UniProtKB/TrEMBL)
RefSeq Acc Id: XP_038941333   ⟸   XM_039085405
- Peptide Label: isoform X1
- UniProtKB: A6HF61 (UniProtKB/TrEMBL),   A0A8L2QVC0 (UniProtKB/TrEMBL)
RefSeq Acc Id: XP_038941334   ⟸   XM_039085406
- Peptide Label: isoform X1
- UniProtKB: A6HF61 (UniProtKB/TrEMBL),   A0A8L2QVC0 (UniProtKB/TrEMBL)
RefSeq Acc Id: XP_063124693   ⟸   XM_063268623
- Peptide Label: isoform X1

Protein Structures
Name Modeler Protein Id AA Range Protein Structure
AF-Q5RJY4-F1-model_v2 AlphaFold Q5RJY4 1-325 view protein structure

Transcriptome

eQTL   View at Phenogen
WGCNA   View at Phenogen
Tissue/Strain Expression   View at Phenogen

Promoters
RGD ID:13697253
Promoter ID:EPDNEW_R7778
Type:multiple initiation site
Name:Dhrs7b_1
Description:dehydrogenase/reductase 7B
SO ACC ID:SO:0000170
Source:EPDNEW (Eukaryotic Promoter Database, http://epd.vital-it.ch/)
Experiment Methods:Single-end sequencing.
Position:
Rat AssemblyChrPosition (strand)Source
Rnor_6.01047,065,836 - 47,065,896EPDNEW

Additional Information

Database Acc Id Source(s)
AGR Gene RGD:1311243 AgrOrtholog
BioCyc Gene G2FUF-24839 BioCyc
Ensembl Genes ENSRNOG00000005360 Ensembl, ENTREZGENE, UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  ENSRNOG00055025492 UniProtKB/Swiss-Prot
  ENSRNOG00060030543 UniProtKB/Swiss-Prot
  ENSRNOG00065008238 UniProtKB/Swiss-Prot
Ensembl Transcript ENSRNOT00000065294.3 UniProtKB/TrEMBL
  ENSRNOT00000066250 ENTREZGENE
  ENSRNOT00000066250.4 UniProtKB/Swiss-Prot
  ENSRNOT00000077868.2 UniProtKB/TrEMBL
  ENSRNOT00055044041 UniProtKB/Swiss-Prot
  ENSRNOT00060053080 UniProtKB/Swiss-Prot
  ENSRNOT00065013068 UniProtKB/Swiss-Prot
Gene3D-CATH NAD(P)-binding Rossmann-like Domain UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
IMAGE_CLONE IMAGE:7305216 IMAGE-MGC_LOAD
InterPro NAD(P)-bd_dom_sf UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  Sc_DH/Rdtase_CS UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  SDR_fam UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
KEGG Report rno:287380 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
MGC_CLONE MGC:105547 IMAGE-MGC_LOAD
NCBI Gene 287380 ENTREZGENE
PANTHER DEHYDROGENASE/REDUCTASE SDR FAMILY MEMBER 7B UniProtKB/Swiss-Prot
  DEHYDROGENASE/REDUCTASE SDR FAMILY MEMBER 7B UniProtKB/Swiss-Prot
  DEHYDROGENASE/REDUCTASE SDR FAMILY MEMBER 7B UniProtKB/TrEMBL
  DEHYDROGENASE/REDUCTASE SDR FAMILY MEMBER 7B UniProtKB/TrEMBL
Pfam adh_short UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
PhenoGen Dhrs7b PhenoGen
PIRSF 11-beta-HSD1 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
PRINTS GDHRDH UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  SDRFAMILY UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
PROSITE ADH_SHORT UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  PROKAR_LIPOPROTEIN UniProtKB/TrEMBL
RatGTEx ENSRNOG00000005360 RatGTEx
  ENSRNOG00055025492 RatGTEx
  ENSRNOG00060030543 RatGTEx
  ENSRNOG00065008238 RatGTEx
Superfamily-SCOP SSF51735 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
UniProt A0A8L2QVC0 ENTREZGENE, UniProtKB/TrEMBL
  A0A8L2R5J7 ENTREZGENE, UniProtKB/TrEMBL
  A4GWE3 ENTREZGENE
  A6HF59 ENTREZGENE, UniProtKB/TrEMBL
  A6HF60 ENTREZGENE, UniProtKB/TrEMBL
  A6HF61 ENTREZGENE, UniProtKB/TrEMBL
  DRS7B_RAT UniProtKB/Swiss-Prot, ENTREZGENE
UniProt Secondary A4GWE3 UniProtKB/Swiss-Prot


Nomenclature History
Date Current Symbol Current Name Previous Symbol Previous Name Description Reference Status
2016-06-01 Dhrs7b  dehydrogenase/reductase 7B  Dhrs7b  dehydrogenase/reductase (SDR family) member 7B  Nomenclature updated to reflect human and mouse nomenclature 1299863 APPROVED
2006-03-30 Dhrs7b  dehydrogenase/reductase (SDR family) member 7B  RGD1311243  similar to DKFZP566O084 protein  Symbol and Name updated 1299863 APPROVED
2005-12-06 RGD1311243  similar to DKFZP566O084 protein  RGD1311243_predicted  similar to DKFZP566O084 protein (predicted)  Symbol and Name updated 1559027 APPROVED
2005-01-20 RGD1311243_predicted  similar to DKFZP566O084 protein (predicted)  LOC287380_predicted    Symbol and Name status set to approved 1331353 APPROVED
2005-01-12 LOC287380_predicted  similar to DKFZP566O084 protein (predicted)      Symbol and Name status set to provisional 70820 PROVISIONAL