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Gene: Csf2 (colony stimulating factor 2) Rattus norvegicus
Symbol: Csf2
Name: colony stimulating factor 2
RGD ID: 621065
Description: Exhibits cytokine activity. Involved in several processes, including cellular response to lipopolysaccharide; macrophage activation; and response to silicon dioxide. Localizes to extracellular space. Used to study myocardial infarction. Biomarker of abdominal aortic aneurysm; interstitial cystitis; and lung disease (multiple). Human ortholog(s) of this gene implicated in acute myeloid leukemia; juvenile myelomonocytic leukemia; neutropenia; pulmonary alveolar proteinosis; and visceral leishmaniasis. Orthologous to human CSF2 (colony stimulating factor 2); PARTICIPATES IN Fc epsilon receptor mediated signaling pathway; granulocyte-macrophage colony-stimulating factor signaling pathway; syndecan signaling pathway; INTERACTS WITH (+)-pilocarpine; 2-amino-2-deoxy-D-glucopyranose; acrylamide.
Type: protein-coding
RefSeq Status: VALIDATED
Also known as: colony stimulating factor 2 (granulocyte-macrophage); colony-stimulating factor; CSF; Gm-csf; Gmcsf; granulocyte-macrophage colony-stimulating factor
Homo sapiens (human) : CSF2 (colony stimulating factor 2)  HGNC  Alliance
Mus musculus (house mouse) : Csf2 (colony stimulating factor 2 (granulocyte-macrophage))  MGI  Alliance
Chinchilla lanigera (long-tailed chinchilla) : Csf2 (colony stimulating factor 2)
Pan paniscus (bonobo/pygmy chimpanzee) : CSF2 (colony stimulating factor 2)
Canis lupus familiaris (dog) : CSF2 (colony stimulating factor 2)
Ictidomys tridecemlineatus (thirteen-lined ground squirrel) : Csf2 (colony stimulating factor 2)
Sus scrofa (pig) : CSF2 (colony stimulating factor 2)
Chlorocebus sabaeus (African green monkey) : CSF2 (colony stimulating factor 2)
Heterocephalus glaber (naked mole-rat) : Csf2 (colony stimulating factor 2)
more info ...
Latest Assembly: Rnor_6.0 - RGSC Genome Assembly v6.0
Rat AssemblyChrPosition (strand)SourceGenome Browsers
Rnor_6.01039,602,089 - 39,604,070 (-)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl1039,602,089 - 39,604,070 (-)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.01039,379,120 - 39,381,430 (-)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.41039,665,850 - 39,667,831 (-)NCBIRGSC3.4rn4RGSC3.4
RGSC_v3.11039,679,472 - 39,681,403 (-)NCBI
Celera1037,727,629 - 37,729,611 (-)NCBICelera
Cytogenetic Map10q22NCBI
JBrowse: View Region in Genome Browser (JBrowse)

Disease Annotations
Gene-Chemical Interaction Annotations
Gene Ontology Annotations
Molecular Pathway Annotations
References - curated
References - uncurated


Comparative Map Data
QTLs in Region (Rnor_6.0)
miRNA Target Status


RNA-SEQ Expression


Nucleotide Sequences
Protein Sequences

Strain Variation

Strain Sequence Variants (Rnor 6.0)

Additional Information

External Database Links
Nomenclature History
More on Csf2
Alliance Gene
Ensembl Gene
JBrowse: rn5 rn6
NCBI Genome Data Viewer

RGD Object Information
RGD ID: 621065
Created: 2002-08-06
Species: Rattus norvegicus
Last Modified: 2020-10-13
Status: ACTIVE


RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.