Gene: Alox15 (arachidonate 15-lipoxygenase) Rattus norvegicus
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Symbol: Alox15
Name: arachidonate 15-lipoxygenase
Description: ENCODES a protein that exhibits arachidonate 12-lipoxygenase activity; arachidonate 15-lipoxygenase activity; hepoxilin A3 synthase activity; INVOLVED IN arachidonic acid metabolic process; hepoxilin biosynthetic process; lipoxygenase pathway; PARTICIPATES IN lipoxygenase mediated pathway of arachidonic acid metabolism; acetylsalicylic acid pharmacodynamics pathway; antipyrine drug pathway; ASSOCIATED WITH brain ischemia; congestive heart failure; glomerulonephritis; FOUND IN cytosol; cytoplasm (ortholog); extrinsic component of cytoplasmic side of plasma membrane (ortholog); INTERACTS WITH (5Z,8Z,11Z,13E)-15-HETE; (S)-10-[(DIMETHYLAMINO)METHYL]-4-ETHYL-4,9-DIHYDROXY-1H-PYRANO[3',4':6,7]INOLIZINO[1,2-B]-QUINOLINE-3,14(4H,12H)-DIONE; 2,3,7,8-tetrachlorodibenzodioxine
Type: protein-coding
RefSeq Status: PROVISIONAL
Also known as: 12-LOX; 12/15-lipoxygenase; 12/15-LOX; 15-LOX; Alox12; Alox12l; arachidonate 12-lipoxygenase, leukocyte-type; arachidonate omega-6 lipoxygenase
Orthologs:
Homo sapiens (human) : ALOX15 (arachidonate 15-lipoxygenase)  HGNC  Alliance
Mus musculus (house mouse) : Alox15 (arachidonate 15-lipoxygenase)  MGI  Alliance
Chinchilla lanigera (long-tailed chinchilla) : Alox15 (arachidonate 15-lipoxygenase)
Pan paniscus (bonobo/pygmy chimpanzee) : ALOX15 (arachidonate 15-lipoxygenase)
Canis lupus familiaris (dog) : ALOX15 (arachidonate 15-lipoxygenase)
Ictidomys tridecemlineatus (thirteen-lined ground squirrel) : Alox15 (arachidonate 15-lipoxygenase)
Sus scrofa (pig) : ALOX15 (arachidonate 15-lipoxygenase)
more info ...
Is Marker For: Strains:   SD  
Latest Assembly: Rnor_6.0 - RGSC Genome Assembly v6.0
Position:
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Rnor_6.01056,953,692 - 56,962,145 (-)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_5.01056,704,488 - 56,713,186 (-)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.41057,185,939 - 57,194,388 (-)NCBIRGSC3.4rn4RGSC3.4
RGSC_v3.11057,199,562 - 57,208,011 (-)NCBI
Celera1054,211,640 - 54,220,083 (-)NCBICelera
Cytogenetic Map10q24NCBI
JBrowse: View Region in Genome Browser (JBrowse)
Model


Disease Annotations
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Molecular Pathway Annotations
References - curated
References - uncurated
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Genomics

Comparative Map Data
Position Markers
QTLs in Region (Rnor_6.0)
Related Rat Strains
miRNA Target Status

Sequence

Nucleotide Sequences
Protein Sequences
Transcriptome
Promoters

Strain Variation

Strain Sequence Variants (Rnor 5.0)
Damaging Variants

Additional Information

External Database Links
Nomenclature History
RGD Curation Notes
 
More on Alox15
Alliance Gene
NCBI Gene
Ensembl Gene
JBrowse: rn5 rn6
NCBI Genome Data Viewer

RGD Object Information
RGD ID: 70493
Created: 2002-05-02
Species: Rattus norvegicus
Last Modified: 2019-01-30
Status: ACTIVE