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Gene: Havcr2 (hepatitis A virus cellular receptor 2) Rattus norvegicus
Symbol: Havcr2
Name: hepatitis A virus cellular receptor 2
RGD ID: 1305233
Description: Predicted to have metal ion binding activity. Predicted to be involved in several processes, including regulation of cytokine production; regulation of leukocyte activation; and toll-like receptor signaling pathway. Localizes to cell surface. Biomarker of transient cerebral ischemia. Human ortholog(s) of this gene implicated in renal cell carcinoma. Orthologous to human HAVCR2 (hepatitis A virus cellular receptor 2); INTERACTS WITH 2,3,7,8-tetrachlorodibenzodioxine; 2,4-dinitrotoluene; 3,3',4,4',5-pentachlorobiphenyl.
Type: protein-coding
RefSeq Status: VALIDATED
Also known as: HAVcr-2; hepatitis A virus cellular receptor 2 homolog; LOC363578; T cell immunoglobulin mucin-3; T-cell immunoglobulin and mucin domain-containing protein 3; T-cell immunoglobulin mucin receptor 3; T-cell membrane protein 3; TIM-3; tim3; TIMD-3
Homo sapiens (human) : HAVCR2 (hepatitis A virus cellular receptor 2)  HGNC  Alliance
Mus musculus (house mouse) : Havcr2 (hepatitis A virus cellular receptor 2)  MGI  Alliance
Chinchilla lanigera (long-tailed chinchilla) : Havcr2 (hepatitis A virus cellular receptor 2)
Pan paniscus (bonobo/pygmy chimpanzee) : HAVCR2 (hepatitis A virus cellular receptor 2)
Canis lupus familiaris (dog) : HAVCR2 (hepatitis A virus cellular receptor 2)
Ictidomys tridecemlineatus (thirteen-lined ground squirrel) : Havcr2 (hepatitis A virus cellular receptor 2)
Sus scrofa (pig) : HAVCR2 (hepatitis A virus cellular receptor 2)
Chlorocebus sabaeus (African green monkey) : HAVCR2 (hepatitis A virus cellular receptor 2)
Heterocephalus glaber (naked mole-rat) : Havcr2 (hepatitis A virus cellular receptor 2)
more info ...
Latest Assembly: Rnor_6.0 - RGSC Genome Assembly v6.0
Rat AssemblyChrPosition (strand)SourceGenome Browsers
Rnor_6.01031,561,838 - 31,590,624 (+)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl1031,561,895 - 31,588,943 (+)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.01031,376,989 - 31,404,231 (+)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.41031,585,703 - 31,610,825 (+)NCBIRGSC3.4rn4RGSC3.4
RGSC_v3.11031,579,175 - 31,610,030 (+)NCBI
Celera1030,333,452 - 30,358,912 (+)NCBICelera
Cytogenetic Map10q21NCBI
JBrowse: View Region in Genome Browser (JBrowse)

Disease Annotations
Gene-Chemical Interaction Annotations
Gene Ontology Annotations
References - curated
References - uncurated


Comparative Map Data
Position Markers
QTLs in Region (Rnor_6.0)
miRNA Target Status


RNA-SEQ Expression


Nucleotide Sequences
Protein Sequences

Strain Variation

Strain Sequence Variants (Rnor 6.0)
Damaging Variants

Additional Information

External Database Links
Nomenclature History
More on Havcr2
Alliance Gene
Ensembl Gene
JBrowse: rn5 rn6
NCBI Genome Data Viewer

RGD Object Information
RGD ID: 1305233
Created: 2005-01-12
Species: Rattus norvegicus
Last Modified: 2020-08-20
Status: ACTIVE


RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.