(+)-schisandrin B multiple interactions EXP 6480464 schizandrin B inhibits the reaction [Carbon Tetrachloride results in increased expression of SQSTM1 mRNA] CTD PMID:31150632 (+)-Tetrandrine decreases expression ISO RGD:736484 6480464 tetrandrine results in decreased expression of SQSTM1 protein CTD PMID:25266202 (-)-anisomycin multiple interactions ISO RGD:736485 6480464 Anisomycin promotes the reaction [triethylene glycol dimethacrylate results in increased expression of SQSTM1 protein] CTD PMID:33684387 (-)-anisomycin multiple interactions EXP 6480464 Anisomycin promotes the reaction [Colistin results in increased degradation of SQSTM1 protein] CTD PMID:28842171 (-)-epigallocatechin 3-gallate multiple interactions ISO RGD:736484 6480464 [potassium chromate(VI) co-treated with epigallocatechin gallate] results in increased expression of SQSTM1 mRNA CTD PMID:22079256 (-)-epigallocatechin 3-gallate multiple interactions ISO RGD:736485 6480464 epigallocatechin gallate inhibits the reaction [[Oxygen deficiency co-treated with Blood Glucose deficiency] results in decreased expression of SQSTM1 protein], epigallocatechin gallate inhibits the reaction [Hydrogen Peroxide results in decreased expression of SQSTM1 protein] CTD PMID:34740634 (1->4)-beta-D-glucan multiple interactions ISO RGD:736485 6480464 [perfluorooctane sulfonic acid co-treated with Cellulose] results in increased expression of SQSTM1 mRNA CTD PMID:36331819 (20S)-ginsenoside Rg3 multiple interactions ISO RGD:736485 6480464 ginsenoside Rg3 inhibits the reaction [Cisplatin results in increased expression of SQSTM1 protein] CTD PMID:34423507 (20S)-ginsenoside Rg3 multiple interactions ISO RGD:736484 6480464 3-methyladenine affects the reaction [ginsenoside Rg3 affects the reaction [Cisplatin affects the expression of SQSTM1 protein]], ginsenoside Rg3 affects the reaction [Cisplatin affects the expression of SQSTM1 protein] CTD PMID:34423507 (S)-nicotine increases expression ISO RGD:736484 6480464 Nicotine results in increased expression of SQSTM1 protein CTD PMID:33010382 (S)-nicotine multiple interactions ISO RGD:736485 6480464 Nicotine promotes the reaction [Dextran Sulfate results in decreased expression of SQSTM1 protein] CTD PMID:31926917 (S)-nicotine multiple interactions ISO RGD:736484 6480464 dorsomorphin inhibits the reaction [Nicotine promotes the reaction [Dextran Sulfate results in decreased expression of SQSTM1 protein]], Nicotine promotes the reaction [Dextran Sulfate results in decreased expression of SQSTM1 protein] CTD PMID:31926917 1,2-dichloroethane increases expression ISO RGD:736485 6480464 ethylene dichloride results in increased expression of SQSTM1 mRNA CTD PMID:28960355 1,2-dimethylhydrazine multiple interactions ISO RGD:736485 6480464 [1, 2-Dimethylhydrazine co-treated with Folic Acid] results in decreased expression of SQSTM1 mRNA CTD PMID:22206623 1,2-dimethylhydrazine decreases expression ISO RGD:736485 6480464 1, 2-Dimethylhydrazine results in decreased expression of SQSTM1 mRNA CTD PMID:22206623 1,3-benzothiazole-2-thiol increases expression ISO RGD:736484 6480464 captax results in increased expression of SQSTM1 mRNA CTD PMID:24211530 1,4-benzoquinone decreases expression ISO RGD:736484 6480464 quinone results in decreased expression of SQSTM1 protein CTD PMID:29567065 1,4-benzoquinone multiple interactions ISO RGD:736484 6480464 Cyclosporine inhibits the reaction [quinone results in decreased expression of SQSTM1 protein] CTD PMID:29567065 17alpha-ethynylestradiol decreases expression ISO RGD:736485 6480464 Ethinyl Estradiol results in decreased expression of SQSTM1 mRNA CTD PMID:17555576 17alpha-ethynylestradiol decreases expression EXP 6480464 Ethinyl Estradiol results in decreased expression of SQSTM1 mRNA CTD PMID:17108234 17alpha-ethynylestradiol multiple interactions ISO RGD:736485 6480464 [Tetrachlorodibenzodioxin co-treated with Ethinyl Estradiol] results in increased expression of SQSTM1 mRNA CTD PMID:17942748 17alpha-ethynylestradiol increases expression ISO RGD:736485 6480464 Ethinyl Estradiol results in increased expression of SQSTM1 mRNA CTD PMID:17942748 17beta-estradiol decreases expression ISO RGD:736484 6480464 Estradiol results in decreased expression of SQSTM1 mRNA CTD PMID:16474171 17beta-estradiol increases expression ISO RGD:736484 6480464 Estradiol results in increased expression of SQSTM1 mRNA CTD PMID:20106945 2,2',4,4'-Tetrabromodiphenyl ether increases expression ISO RGD:736484 6480464 2 more ... CTD PMID:25305463 2,2',4,4'-Tetrabromodiphenyl ether decreases degradation EXP 6480464 2 more ... CTD PMID:30029115 2,2',5,5'-tetrachlorobiphenyl multiple interactions EXP 6480464 3-methyladenine inhibits the reaction [2 more ... CTD PMID:29518472 2,2',5,5'-tetrachlorobiphenyl increases expression ISO RGD:736484 6480464 2 more ... CTD PMID:29518472 2,2',5,5'-tetrachlorobiphenyl multiple interactions ISO RGD:736484 6480464 3-methyladenine inhibits the reaction [2 more ... CTD PMID:29518472 2,2',5,5'-tetrachlorobiphenyl increases expression EXP 6480464 2 more ... CTD PMID:29518472 2,3',4,4',5-Pentachlorobiphenyl multiple interactions EXP 6480464 1-(2-(3-(4-methoxyphenyl)propoxy)-4-methoxyphenylethyl)-1H-imidazole inhibits the reaction [2 more ... CTD PMID:32895711 2,3',4,4',5-Pentachlorobiphenyl decreases expression EXP 6480464 2 more ... CTD PMID:32895711 2,3,7,8-tetrachlorodibenzodioxine multiple interactions ISO RGD:736485 6480464 [Tetrachlorodibenzodioxin co-treated with Ethinyl Estradiol] results in increased expression of SQSTM1 mRNA CTD PMID:17942748 2,3,7,8-tetrachlorodibenzodioxine increases expression EXP 6480464 Tetrachlorodibenzodioxin results in increased expression of SQSTM1 mRNA CTD PMID:33387578 , PMID:34747641 2,3,7,8-tetrachlorodibenzodioxine increases expression ISO RGD:736485 6480464 Tetrachlorodibenzodioxin results in increased expression of SQSTM1 mRNA CTD PMID:15034205 2,3,7,8-tetrachlorodibenzodioxine affects expression ISO RGD:736485 6480464 Tetrachlorodibenzodioxin affects the expression of SQSTM1 mRNA CTD PMID:21570461 2,3,7,8-tetrachlorodibenzodioxine affects expression EXP 6480464 Tetrachlorodibenzodioxin affects the expression of SQSTM1 mRNA CTD PMID:22298810 2,4,6-trinitrobenzenesulfonic acid multiple interactions EXP 6480464 dapagliflozin inhibits the reaction [Trinitrobenzenesulfonic Acid results in increased expression of SQSTM1 protein], Mesalamine inhibits the reaction [Trinitrobenzenesulfonic Acid results in increased expression of SQSTM1 protein] CTD PMID:33412153 2,4,6-trinitrobenzenesulfonic acid increases expression EXP 6480464 Trinitrobenzenesulfonic Acid results in increased expression of SQSTM1 protein CTD PMID:33412153 2,4-D multiple interactions EXP 6480464 lycium barbarum polysaccharide inhibits the reaction [2 more ... CTD PMID:34464015 2,4-D increases expression ISO RGD:736485 6480464 2 more ... CTD PMID:35099110 2,4-D multiple interactions ISO RGD:736485 6480464 lycium barbarum polysaccharide inhibits the reaction [2 more ... CTD PMID:35099110 2,4-D increases expression EXP 6480464 2 more ... CTD PMID:34464015 2,4-dibromophenyl 2,4,5-tribromophenyl ether increases expression ISO RGD:736484 6480464 2 more ... CTD PMID:26705709 2-(chloromethyl)pyridine increases expression ISO RGD:736484 6480464 2-chloromethylpyridine results in increased expression of SQSTM1 mRNA CTD PMID:26198647 2-butoxyethanol increases expression ISO RGD:736485 6480464 n-butoxyethanol results in increased expression of SQSTM1 mRNA CTD PMID:19812364 2-deoxy-D-glucose multiple interactions ISO RGD:736484 6480464 [bafilomycin A co-treated with Deoxyglucose co-treated with demycarosyl-3D-digitoxosylmithramycin SK] affects the expression of SQSTM1 protein more ... CTD PMID:26079942 2-hydroxyethyl methacrylate increases expression ISO RGD:736484 6480464 hydroxyethyl methacrylate results in increased expression of SQSTM1 mRNA, hydroxyethyl methacrylate results in increased expression of SQSTM1 protein CTD PMID:30497689 2-hydroxypropanoic acid increases expression ISO RGD:736484 6480464 Lactic Acid results in increased expression of SQSTM1 mRNA CTD PMID:30851411 2-methoxyethanol increases expression EXP 6480464 methyl cellosolve results in increased expression of SQSTM1 mRNA CTD PMID:9681501 2-tert-butylhydroquinone increases expression ISO RGD:736484 6480464 2-tert-butylhydroquinone results in increased expression of SQSTM1 protein CTD PMID:23589329 2-tert-butylhydroquinone decreases expression ISO RGD:736484 6480464 2-tert-butylhydroquinone results in decreased expression of SQSTM1 mRNA CTD PMID:35724838 2-tert-butylhydroquinone increases expression EXP 6480464 2-tert-butylhydroquinone results in increased expression of SQSTM1 protein CTD PMID:31726083 2-tert-butylhydroquinone multiple interactions EXP 6480464 [thallium nitrate co-treated with 2-tert-butylhydroquinone] results in increased expression of SQSTM1 protein CTD PMID:31726083 20-hydroxyecdysone affects expression ISO RGD:736484 6480464 Ecdysterone affects the expression of SQSTM1 protein CTD PMID:33878320 3,3',5,5'-tetrabromobisphenol A increases expression ISO RGD:736485 6480464 tetrabromobisphenol A results in increased expression of SQSTM1 mRNA CTD PMID:25172293 3,3',5-triiodo-L-thyronine multiple interactions ISO RGD:736484 6480464 [THRA protein co-treated with Triiodothyronine] results in decreased expression of SQSTM1 protein more ... CTD PMID:24262987 3,3',5-triiodo-L-thyronine increases expression ISO RGD:736485 6480464 Triiodothyronine results in increased expression of SQSTM1 mRNA CTD PMID:30209975 3,4-methylenedioxymethamphetamine increases expression ISO RGD:736484 6480464 N-Methyl-3, 4-methylenedioxyamphetamine results in increased expression of SQSTM1 protein CTD PMID:32186374 3,4-methylenedioxymethamphetamine multiple interactions ISO RGD:736484 6480464 bafilomycin A1 promotes the reaction [N-Methyl-3 more ... CTD PMID:32186374 3,4-methylenedioxymethamphetamine increases expression EXP 6480464 N-Methyl-3, 4-methylenedioxyamphetamine results in increased expression of SQSTM1 protein CTD PMID:32186374 3-chloropropane-1,2-diol increases expression EXP 6480464 alpha-Chlorohydrin results in increased expression of SQSTM1 protein CTD PMID:33187795 3-chloropropane-1,2-diol increases expression ISO RGD:736484 6480464 alpha-Chlorohydrin results in increased expression of SQSTM1 protein CTD PMID:32702505 3-chloropropane-1,2-diol multiple interactions ISO RGD:736484 6480464 3-methyladenine promotes the reaction [alpha-Chlorohydrin results in increased expression of SQSTM1 protein] more ... CTD PMID:32702505 3-chloropropane-1,2-diol multiple interactions EXP 6480464 alpha-Chlorohydrin promotes the reaction [glycidol results in increased expression of SQSTM1 protein], glycidol promotes the reaction [alpha-Chlorohydrin results in increased expression of SQSTM1 protein] CTD PMID:33187795 3-isobutyl-1-methyl-7H-xanthine multiple interactions ISO RGD:736484 6480464 [INS protein co-treated with Dexamethasone co-treated with 1-Methyl-3-isobutylxanthine co-treated with Indomethacin co-treated with bis(4-hydroxyphenyl)sulfone] results in increased expression of SQSTM1 mRNA, [INS protein co-treated with Dexamethasone co-treated with 1-Methyl-3-isobutylxanthine co-treated with Indomethacin co-treated with bisphenol A] results in decreased expression of SQSTM1 mRNA CTD PMID:28628672 3-methyladenine increases expression ISO RGD:736484 6480464 3-methyladenine results in increased expression of SQSTM1 protein CTD PMID:20574048 more ... 3-methyladenine multiple interactions ISO RGD:736485 6480464 3-methyladenine inhibits the reaction [anemoside B4 inhibits the reaction [Lipopolysaccharides results in increased expression of SQSTM1 protein]], 3-methyladenine inhibits the reaction [Arsenic Trioxide results in decreased expression of SQSTM1 protein] CTD PMID:33462182 , PMID:34051206 3-methyladenine increases expression ISO RGD:736485 6480464 3-methyladenine results in increased expression of SQSTM1 protein CTD PMID:33462182 3-methyladenine multiple interactions EXP 6480464 3-methyladenine inhibits the reaction [2 more ... CTD PMID:29128638 more ... 3-methyladenine increases expression EXP 6480464 3-methyladenine results in increased expression of SQSTM1 protein CTD PMID:24833599 3-methyladenine multiple interactions ISO RGD:736484 6480464 3-methyladenine affects the reaction [ginsenoside Rg3 affects the reaction [Cisplatin affects the expression of SQSTM1 protein]] more ... CTD PMID:22927544 more ... 3-phenylprop-2-enal increases expression ISO RGD:736484 6480464 cinnamaldehyde results in increased expression of SQSTM1 mRNA CTD PMID:24211530 3H-1,2-dithiole-3-thione increases expression EXP 6480464 1, 2-dithiol-3-thione results in increased expression of SQSTM1 mRNA CTD PMID:19162173 4'-epidoxorubicin multiple interactions EXP 6480464 paeonol inhibits the reaction [Epirubicin results in increased expression of SQSTM1 protein], Sirolimus inhibits the reaction [Epirubicin results in increased expression of SQSTM1 protein] CTD PMID:29505745 4'-epidoxorubicin increases expression EXP 6480464 Epirubicin results in increased expression of SQSTM1 protein CTD PMID:29505745 4,4'-diisothiocyano-trans-stilbene-2,2'-disulfonic acid multiple interactions ISO RGD:736484 6480464 4 more ... CTD PMID:29421517 4,4'-methylene-bis-(2-chloroaniline) increases expression ISO RGD:736484 6480464 Methylenebis(chloroaniline) results in increased expression of SQSTM1 mRNA CTD PMID:26198647 4,4'-sulfonyldiphenol multiple interactions ISO RGD:736484 6480464 [INS protein co-treated with Dexamethasone co-treated with 1-Methyl-3-isobutylxanthine co-treated with Indomethacin co-treated with bis(4-hydroxyphenyl)sulfone] results in increased expression of SQSTM1 mRNA CTD PMID:28628672 4,4'-sulfonyldiphenol multiple interactions EXP 6480464 [bisphenol A co-treated with bisphenol F co-treated with bis(4-hydroxyphenyl)sulfone] results in decreased expression of SQSTM1 mRNA CTD PMID:36041667 4,4'-sulfonyldiphenol affects expression ISO RGD:736484 6480464 bis(4-hydroxyphenyl)sulfone affects the expression of SQSTM1 protein CTD PMID:31945527 4,4'-sulfonyldiphenol decreases methylation ISO RGD:736484 6480464 bis(4-hydroxyphenyl)sulfone results in decreased methylation of SQSTM1 gene CTD PMID:31601247 4-amino-2,6-dinitrotoluene affects expression EXP 6480464 4-amino-2, 6-dinitrotoluene affects the expression of SQSTM1 mRNA CTD PMID:21346803 4-hydroxynon-2-enal increases expression ISO RGD:736485 6480464 4-hydroxy-2-nonenal results in increased expression of SQSTM1 mRNA CTD PMID:19191707 4-hydroxynon-2-enal multiple interactions ISO RGD:736484 6480464 Acetylcysteine inhibits the reaction [4-hydroxy-2-nonenal results in increased expression of SQSTM1 mRNA], TFEB protein affects the reaction [4-hydroxy-2-nonenal results in increased expression of SQSTM1 mRNA] CTD PMID:35550146 4-hydroxynon-2-enal increases expression ISO RGD:736484 6480464 4-hydroxy-2-nonenal results in increased expression of SQSTM1 mRNA CTD PMID:35550146 4-methoxy-TEMPO decreases expression ISO RGD:736484 6480464 4-methoxy-2 more ... CTD PMID:28993908 4-nitro-1,2-phenylenediamine increases expression ISO RGD:736484 6480464 1, 2-diamino-4-nitrobenzene results in increased expression of SQSTM1 mRNA CTD PMID:26198647 4-phenylbutyric acid multiple interactions ISO RGD:736484 6480464 4-phenylbutyric acid inhibits the reaction [Cadmium Chloride results in decreased expression of SQSTM1 protein], 4-phenylbutyric acid inhibits the reaction [Potassium Dichromate results in decreased expression of SQSTM1 protein] CTD PMID:32569804 , PMID:33127495 5-aza-2'-deoxycytidine affects expression ISO RGD:736484 6480464 Decitabine affects the expression of SQSTM1 mRNA CTD PMID:23300844 5-chloro-7-iodoquinolin-8-ol decreases expression ISO RGD:736484 6480464 Clioquinol results in decreased expression of SQSTM1 protein CTD PMID:36396104 6-chloro-2,3,4,9-tetrahydro-1H-carbazole-1-carboxamide multiple interactions ISO RGD:736484 6480464 6-chloro-2 more ... CTD PMID:25943029 , PMID:36336710 6-chloro-2,3,4,9-tetrahydro-1H-carbazole-1-carboxamide decreases degradation ISO RGD:736484 6480464 6-chloro-2 more ... CTD PMID:25943029 7beta-aminocephalosporanic acid increases expression ISO RGD:736484 6480464 7-aminocephalosporanic acid results in increased expression of SQSTM1 mRNA CTD PMID:24211530 abamectin decreases expression ISO RGD:736484 6480464 abamectin results in decreased expression of SQSTM1 protein CTD PMID:30958899 ABT-737 multiple interactions ISO RGD:736484 6480464 [Celecoxib co-treated with ABT-737] results in decreased expression of SQSTM1 protein, ABT-737 promotes the reaction [Silicon Dioxide results in decreased expression of SQSTM1 protein] CTD PMID:20104024 , PMID:32061152 acarbose affects response to substance ISO RGD:736485 6480464 SQSTM1 affects the susceptibility to Acarbose CTD PMID:19207582 acetaldehyde decreases expression ISO RGD:736484 6480464 Acetaldehyde results in decreased expression of SQSTM1 protein CTD PMID:35595033 acetylcholine multiple interactions ISO RGD:736485 6480464 Acetylcholine inhibits the reaction [[Aluminum Chloride results in increased abundance of Aluminum] which results in decreased expression of SQSTM1 protein] CTD PMID:34547296 acrolein increases expression ISO RGD:736484 6480464 Acrolein results in increased expression of SQSTM1 mRNA CTD PMID:24211530 acrolein increases expression EXP 6480464 Acrolein results in increased expression of SQSTM1 protein CTD PMID:35150775 acrolein multiple interactions ISO RGD:736484 6480464 [Acrolein co-treated with methacrylaldehyde co-treated with alpha-pinene co-treated with Ozone] results in increased expression of SQSTM1 mRNA more ... CTD PMID:30205151 , PMID:32699268 acrolein decreases expression ISO RGD:736484 6480464 Acrolein results in decreased expression of SQSTM1 protein CTD PMID:29902662 , PMID:30205151 acrylamide increases expression ISO RGD:736484 6480464 Acrylamide results in increased expression of SQSTM1 mRNA CTD PMID:32763439 acrylamide multiple interactions EXP 6480464 chloroquine diphosphate promotes the reaction [Acrylamide results in increased expression of SQSTM1 protein] CTD PMID:33545342 acrylamide increases expression EXP 6480464 Acrylamide results in increased expression of SQSTM1 protein CTD PMID:33545342 actinomycin D multiple interactions ISO RGD:736485 6480464 Dactinomycin inhibits the reaction [Ethanol results in decreased expression of SQSTM1 protein] CTD PMID:24095927 actinomycin D multiple interactions ISO RGD:736484 6480464 Dactinomycin inhibits the reaction [di-2-pyridylketone-4, 4-dimethyl-3-thiosemicarbazone results in increased expression of SQSTM1 mRNA] CTD PMID:25301941 aflatoxin B1 increases expression ISO RGD:736485 6480464 Aflatoxin B1 results in increased expression of SQSTM1 mRNA, Aflatoxin B1 results in increased expression of SQSTM1 protein CTD PMID:35810998 aflatoxin B1 multiple interactions ISO RGD:736485 6480464 PRKN protein affects the reaction [Aflatoxin B1 results in decreased expression of SQSTM1 mRNA], PRKN protein affects the reaction [Aflatoxin B1 results in decreased expression of SQSTM1 protein] CTD PMID:35304092 aflatoxin B1 decreases expression ISO RGD:736485 6480464 Aflatoxin B1 results in decreased expression of SQSTM1 mRNA, Aflatoxin B1 results in decreased expression of SQSTM1 protein CTD PMID:35304092 AICA ribonucleotide increases expression ISO RGD:736484 6480464 AICA ribonucleotide results in increased expression of SQSTM1 protein CTD PMID:33070465 AICA ribonucleotide multiple interactions ISO RGD:736484 6480464 [AICA ribonucleotide co-treated with Sirolimus] results in increased expression of SQSTM1 protein, TP53 gene mutant form promotes the reaction [AICA ribonucleotide results in increased expression of SQSTM1 protein] CTD PMID:33070465 Ajugasterone C increases expression ISO RGD:736484 6480464 ajugasterone C results in increased expression of SQSTM1 protein CTD PMID:33878320 aldehydo-D-glucose increases expression EXP 6480464 Glucose results in increased expression of SQSTM1 protein CTD PMID:28713934 more ... aldehydo-D-glucose increases expression ISO RGD:736484 6480464 Glucose deficiency results in increased expression of SQSTM1 protein CTD PMID:34580807 aldehydo-D-glucose decreases expression ISO RGD:736484 6480464 Glucose deficiency results in decreased expression of SQSTM1 protein CTD PMID:29649567 aldehydo-D-glucose increases expression ISO RGD:736485 6480464 Glucose results in increased expression of SQSTM1 protein CTD PMID:30459625 aldehydo-D-glucose multiple interactions ISO RGD:736485 6480464 HU 308 inhibits the reaction [Glucose results in increased expression of SQSTM1 protein] CTD PMID:30459625 aldehydo-D-glucose multiple interactions EXP 6480464 3-methyladenine inhibits the reaction [N-(1 more ... CTD PMID:28713934 more ... alginic acid decreases expression ISO RGD:736485 6480464 Alginic Acid results in decreased expression of SQSTM1 protein CTD PMID:35066102 all-trans-retinoic acid multiple interactions ISO RGD:736484 6480464 [Tretinoin co-treated with arsenic trioxide] results in increased expression of SQSTM1 mRNA CTD PMID:15894607 all-trans-retinoic acid increases expression ISO RGD:736484 6480464 Tretinoin results in increased expression of SQSTM1 mRNA CTD PMID:15894607 , PMID:33167477 aloxistatin multiple interactions ISO RGD:736485 6480464 [aloxistatin co-treated with pepstatin] results in increased expression of SQSTM1 protein more ... CTD PMID:26483381 , PMID:32773031 aloxistatin multiple interactions ISO RGD:736484 6480464 [aloxistatin co-treated with pepstatin] results in increased expression of SQSTM1 protein CTD PMID:32186374 alpha,alpha-trehalose increases expression ISO RGD:736485 6480464 Trehalose results in increased expression of SQSTM1 mRNA CTD PMID:23851366 , PMID:30335591 alpha,alpha-trehalose multiple interactions ISO RGD:736485 6480464 TFEB affects the reaction [Trehalose results in increased expression of SQSTM1 mRNA], Trehalose inhibits the reaction [Dronabinol results in increased expression of SQSTM1 protein] CTD PMID:30335591 , PMID:32773031 alpha,alpha-trehalose decreases expression ISO RGD:736485 6480464 Trehalose results in decreased expression of SQSTM1 protein CTD PMID:29486218 alpha-amanitin multiple interactions ISO RGD:736485 6480464 Sirolimus promotes the reaction [Alpha-Amanitin results in decreased expression of SQSTM1 protein] CTD PMID:35175747 alpha-amanitin decreases expression ISO RGD:736485 6480464 Alpha-Amanitin results in decreased expression of SQSTM1 protein CTD PMID:35175747 alpha-D-galactose increases expression ISO RGD:736484 6480464 Galactose results in increased expression of SQSTM1 protein CTD PMID:28302704 , PMID:29426000 alpha-D-galactose multiple interactions ISO RGD:736484 6480464 Hydroxychloroquine inhibits the reaction [Metformin inhibits the reaction [Galactose results in increased expression of SQSTM1 protein]] more ... CTD PMID:28302704 , PMID:29426000 alpha-D-galactose increases expression EXP 6480464 Galactose results in increased expression of SQSTM1 protein CTD PMID:28302704 alpha-pinene multiple interactions ISO RGD:736484 6480464 [Acrolein co-treated with methacrylaldehyde co-treated with alpha-pinene co-treated with Ozone] results in increased expression of SQSTM1 mRNA, [Air Pollutants results in increased abundance of [Acrolein co-treated with methacrylaldehyde co-treated with alpha-pinene co-treated with Ozone]] which results in increased expression of SQSTM1 mRNA CTD PMID:32699268 aluminium atom multiple interactions ISO RGD:736485 6480464 [Aluminum Chloride results in increased abundance of Aluminum] which results in decreased expression of SQSTM1 mRNA more ... CTD PMID:34547296 aluminium(0) multiple interactions ISO RGD:736485 6480464 [Aluminum Chloride results in increased abundance of Aluminum] which results in decreased expression of SQSTM1 mRNA more ... CTD PMID:34547296 amiodarone increases expression ISO RGD:736484 6480464 Amiodarone results in increased expression of SQSTM1 mRNA CTD PMID:19774075 amiodarone affects expression ISO RGD:736484 6480464 Amiodarone affects the expression of SQSTM1 mRNA CTD PMID:36586010 amiodarone decreases expression ISO RGD:736484 6480464 Amiodarone results in decreased expression of SQSTM1 protein CTD PMID:32651653 ammonium chloride affects expression EXP 6480464 Ammonium Chloride affects the expression of SQSTM1 mRNA CTD PMID:16483693 ammonium chloride decreases expression ISO RGD:736484 6480464 Ammonium Chloride results in decreased expression of SQSTM1 protein CTD PMID:29908302 ammonium chloride increases expression ISO RGD:736484 6480464 Ammonium Chloride results in increased expression of SQSTM1 protein CTD PMID:21778691 , PMID:34405320 ammonium chloride multiple interactions ISO RGD:736484 6480464 [Ammonium Chloride co-treated with pentabrominated diphenyl ether 100] results in increased expression of SQSTM1 protein more ... CTD PMID:21778691 more ... ammonium hexachloroplatinate increases expression ISO RGD:736484 6480464 ammonium hexachloroplatinate results in increased expression of SQSTM1 mRNA CTD PMID:24211530 andrographolide increases expression ISO RGD:736484 6480464 andrographolide results in increased expression of SQSTM1 protein CTD PMID:29355602 andrographolide decreases expression ISO RGD:736484 6480464 andrographolide results in decreased expression of SQSTM1 mRNA CTD PMID:35724838 anthra[1,9-cd]pyrazol-6(2H)-one multiple interactions ISO RGD:736484 6480464 pyrazolanthrone inhibits the reaction [morusin results in decreased expression of SQSTM1 protein] more ... CTD PMID:25881548 more ... anthra[1,9-cd]pyrazol-6(2H)-one multiple interactions ISO RGD:736485 6480464 pyrazolanthrone inhibits the reaction [methylmercuric chloride results in increased expression of SQSTM1 protein], pyrazolanthrone inhibits the reaction [triethylene glycol dimethacrylate results in increased expression of SQSTM1 protein] CTD PMID:27667695 , PMID:33684387 anthra[1,9-cd]pyrazol-6(2H)-one multiple interactions EXP 6480464 pyrazolanthrone inhibits the reaction [Colistin results in increased degradation of SQSTM1 protein] CTD PMID:28842171 anthra[1,9-cd]pyrazol-6(2H)-one decreases expression ISO RGD:736484 6480464 pyrazolanthrone results in decreased expression of SQSTM1 protein CTD PMID:27393035 anthra[1,9-cd]pyrazol-6(2H)-one increases expression EXP 6480464 pyrazolanthrone results in increased expression of SQSTM1 protein CTD PMID:24833599 antimonite multiple interactions ISO RGD:736484 6480464 [Antimony Potassium Tartrate results in increased abundance of antimonite] which results in increased expression of SQSTM1 mRNA CTD PMID:32076005 antimycin A multiple interactions ISO RGD:736484 6480464 [oligomycin A co-treated with Antimycin A] results in increased expression of SQSTM1 mRNA, PINK1 protein affects the reaction [[oligomycin A co-treated with Antimycin A] results in increased expression of SQSTM1 mRNA] CTD PMID:28366621 antimycin A increases expression ISO RGD:736485 6480464 Antimycin A results in increased expression of SQSTM1 mRNA CTD PMID:19304788 antirheumatic drug increases expression ISO RGD:736484 6480464 Antirheumatic Agents results in increased expression of SQSTM1 mRNA CTD PMID:24449571 arachidonic acid increases expression ISO RGD:736484 6480464 Arachidonic Acid results in increased expression of SQSTM1 mRNA CTD PMID:16704987 aristolochic acid A increases expression ISO RGD:736484 6480464 aristolochic acid I results in increased expression of SQSTM1 mRNA CTD PMID:33212167 arotinoid acid multiple interactions ISO RGD:736484 6480464 [4-(2-(5 more ... CTD PMID:34480604 arsane multiple interactions ISO RGD:736484 6480464 [Arsenic co-treated with Iron] results in increased expression of SQSTM1 mRNA more ... CTD PMID:29248574 more ... arsane multiple interactions EXP 6480464 [[sodium arsenite results in increased abundance of Arsenic] co-treated with [Sodium Fluoride results in increased abundance of Fluorides]] results in increased expression of SQSTM1 mRNA more ... CTD PMID:31844926 arsane decreases methylation ISO RGD:736484 6480464 Arsenic results in decreased methylation of SQSTM1 5' UTR CTD PMID:31135185 arsane increases expression ISO RGD:736484 6480464 Arsenic results in increased expression of SQSTM1 mRNA, Arsenic results in increased expression of SQSTM1 protein CTD PMID:27413109 more ... arsane increases methylation ISO RGD:736484 6480464 Arsenic results in increased methylation of SQSTM1 gene CTD PMID:25325195 arsane affects methylation ISO RGD:736484 6480464 Arsenic affects the methylation of SQSTM1 gene CTD PMID:25304211 arsenic atom multiple interactions ISO RGD:736484 6480464 [Arsenic co-treated with Iron] results in increased expression of SQSTM1 mRNA more ... CTD PMID:29248574 more ... arsenic atom multiple interactions EXP 6480464 [[sodium arsenite results in increased abundance of Arsenic] co-treated with [Sodium Fluoride results in increased abundance of Fluorides]] results in increased expression of SQSTM1 mRNA more ... CTD PMID:31844926 arsenic atom decreases methylation ISO RGD:736484 6480464 Arsenic results in decreased methylation of SQSTM1 5' UTR CTD PMID:31135185 arsenic atom increases expression ISO RGD:736484 6480464 Arsenic results in increased expression of SQSTM1 mRNA, Arsenic results in increased expression of SQSTM1 protein CTD PMID:27413109 more ... arsenic atom increases methylation ISO RGD:736484 6480464 Arsenic results in increased methylation of SQSTM1 gene CTD PMID:25325195 arsenic atom affects methylation ISO RGD:736484 6480464 Arsenic affects the methylation of SQSTM1 gene CTD PMID:25304211 arsenite(3-) increases expression ISO RGD:736485 6480464 arsenite results in increased expression of SQSTM1 mRNA, arsenite results in increased expression of SQSTM1 protein CTD PMID:15894712 , PMID:34929507 arsenite(3-) increases expression ISO RGD:736484 6480464 arsenite results in increased expression of SQSTM1 protein CTD PMID:34929507 arsenite(3-) decreases expression ISO RGD:736484 6480464 arsenite results in decreased expression of SQSTM1 protein CTD PMID:33097607 arsenite(3-) multiple interactions ISO RGD:736484 6480464 [sodium arsenite results in increased abundance of arsenite] inhibits the reaction [Cycloheximide results in decreased expression of SQSTM1 protein] more ... CTD PMID:31781319 more ... arsenite(3-) multiple interactions EXP 6480464 Selenium inhibits the reaction [arsenite results in increased expression of SQSTM1 protein] CTD PMID:29324385 arsenite(3-) increases expression EXP 6480464 arsenite results in increased expression of SQSTM1 protein CTD PMID:29324385 arsenite(3-) multiple interactions ISO RGD:736485 6480464 [arsenite co-treated with Benzo(a)pyrene] results in increased expression of SQSTM1 mRNA, BECN1 protein affects the reaction [arsenite results in increased expression of SQSTM1 protein] CTD PMID:15894712 , PMID:34929507 arsenous acid affects binding ISO RGD:736484 6480464 Arsenic Trioxide binds to SQSTM1 protein CTD PMID:30237564 arsenous acid affects expression ISO RGD:736485 6480464 Arsenic Trioxide affects the expression of SQSTM1 protein CTD PMID:33462182 arsenous acid affects expression ISO RGD:736484 6480464 Arsenic Trioxide affects the expression of SQSTM1 protein CTD PMID:33462182 arsenous acid decreases expression ISO RGD:736484 6480464 Arsenic Trioxide results in decreased expression of SQSTM1 protein CTD PMID:29307831 more ... arsenous acid decreases expression ISO RGD:736485 6480464 Arsenic Trioxide results in decreased expression of SQSTM1 protein CTD PMID:29111283 more ... arsenous acid increases expression ISO RGD:736484 6480464 Arsenic Trioxide results in increased expression of SQSTM1 mRNA, Arsenic Trioxide results in increased expression of SQSTM1 protein CTD PMID:20200477 more ... arsenous acid increases expression EXP 6480464 Arsenic Trioxide results in increased expression of SQSTM1 protein CTD PMID:30551535 more ... arsenous acid multiple interactions ISO RGD:736485 6480464 3-methyladenine inhibits the reaction [Arsenic Trioxide results in decreased expression of SQSTM1 protein] more ... CTD PMID:30237538 more ... arsenous acid decreases expression EXP 6480464 Arsenic Trioxide results in decreased expression of SQSTM1 protein CTD PMID:29111283 arsenous acid increases expression ISO RGD:736485 6480464 Arsenic Trioxide results in increased expression of SQSTM1 mRNA, Arsenic Trioxide results in increased expression of SQSTM1 protein CTD PMID:24801902 more ... arsenous acid multiple interactions ISO RGD:736484 6480464 3-methyladenine inhibits the reaction [Arsenic Trioxide results in decreased expression of SQSTM1 protein] more ... CTD PMID:15894607 more ... arsenous acid multiple interactions EXP 6480464 ferrostatin-1 inhibits the reaction [Arsenic Trioxide results in increased expression of SQSTM1 protein] more ... CTD PMID:29111283 more ... arsenous acid decreases response to substance ISO RGD:736484 6480464 SQSTM1 protein results in decreased susceptibility to Arsenic Trioxide CTD PMID:20707922 artesunate multiple interactions ISO RGD:736484 6480464 Chloroquine inhibits the reaction [Artesunate results in decreased expression of SQSTM1 protein] CTD PMID:30551460 artesunate decreases expression ISO RGD:736484 6480464 Artesunate results in decreased expression of SQSTM1 mRNA, Artesunate results in decreased expression of SQSTM1 protein CTD PMID:30551460 astemizole increases expression EXP 6480464 Astemizole results in increased expression of SQSTM1 mRNA CTD PMID:20221588 astragaloside IV multiple interactions EXP 6480464 astragaloside A inhibits the reaction [Cisplatin results in increased expression of SQSTM1 protein] CTD PMID:30842369 atazanavir sulfate multiple interactions ISO RGD:736484 6480464 [Atazanavir Sulfate co-treated with Glycochenodeoxycholic Acid co-treated with Deoxycholic Acid co-treated with Chenodeoxycholic Acid co-treated with Glycodeoxycholic Acid co-treated with Glycocholic Acid] results in increased expression of SQSTM1 mRNA CTD PMID:32152650 atazanavir sulfate increases expression ISO RGD:736484 6480464 Atazanavir Sulfate results in increased expression of SQSTM1 mRNA CTD PMID:32152650 atorvastatin calcium multiple interactions EXP 6480464 [dapagliflozin co-treated with Atorvastatin] inhibits the reaction [[Dietary Fats co-treated with Fructose] results in increased expression of SQSTM1 protein] CTD PMID:34939712 atrazine increases expression ISO RGD:736485 6480464 Atrazine results in increased expression of SQSTM1 mRNA more ... CTD PMID:30360616 , PMID:33485040 atrazine decreases expression EXP 6480464 Atrazine results in decreased expression of SQSTM1 mRNA, Atrazine results in decreased expression of SQSTM1 protein CTD PMID:30084861 atrazine multiple interactions ISO RGD:736485 6480464 Lycopene inhibits the reaction [Atrazine results in increased expression of SQSTM1 mRNA alternative form] more ... CTD PMID:30360616 avobenzone increases expression ISO RGD:736484 6480464 avobenzone results in increased expression of SQSTM1 mRNA CTD PMID:31016361 azathioprine increases expression ISO RGD:736484 6480464 Azathioprine results in increased expression of SQSTM1 mRNA CTD PMID:22623647 , PMID:26198647 bafilomycin A1 multiple interactions ISO RGD:736485 6480464 [bafilomycin A1 co-treated with Rotenone] results in increased expression of SQSTM1 protein more ... CTD PMID:24238063 more ... bafilomycin A1 increases expression ISO RGD:736484 6480464 bafilomycin A1 results in increased expression of SQSTM1 protein CTD PMID:21778691 more ... bafilomycin A1 increases expression ISO RGD:736485 6480464 bafilomycin A1 results in increased expression of SQSTM1 protein CTD PMID:24889822 more ... bafilomycin A1 multiple interactions EXP 6480464 bafilomycin A1 promotes the reaction [Hydrogen Peroxide results in increased expression of SQSTM1 protein] CTD PMID:24889822 bafilomycin A1 multiple interactions ISO RGD:736484 6480464 [Resveratrol co-treated with bafilomycin A1] results in increased expression of SQSTM1 protein more ... CTD PMID:21778691 more ... Bardoxolone methyl affects expression ISO RGD:736484 6480464 bardoxolone methyl affects the expression of SQSTM1 mRNA CTD PMID:34480604 Bardoxolone methyl decreases expression ISO RGD:736484 6480464 bardoxolone methyl results in decreased expression of SQSTM1 mRNA CTD PMID:35724838 benzidine increases expression ISO RGD:736484 6480464 benzidine results in increased expression of SQSTM1 mRNA CTD PMID:26198647 benzo[a]pyrene multiple interactions ISO RGD:736485 6480464 [arsenite co-treated with Benzo(a)pyrene] results in increased expression of SQSTM1 mRNA, AHR protein promotes the reaction [Benzo(a)pyrene results in increased expression of SQSTM1 mRNA] CTD PMID:15034205 , PMID:15894712 benzo[a]pyrene multiple interactions EXP 6480464 Resveratrol affects the reaction [Benzo(a)pyrene affects the expression of SQSTM1 protein] CTD PMID:32619457 benzo[a]pyrene affects methylation ISO RGD:736484 6480464 Benzo(a)pyrene affects the methylation of SQSTM1 5' UTR CTD PMID:27901495 benzo[a]pyrene increases expression ISO RGD:736484 6480464 Benzo(a)pyrene results in increased expression of SQSTM1 mRNA, Benzo(a)pyrene results in increased expression of SQSTM1 protein CTD PMID:20106945 more ... benzo[a]pyrene increases expression ISO RGD:736485 6480464 Benzo(a)pyrene results in increased expression of SQSTM1 mRNA CTD PMID:15034205 more ... benzo[a]pyrene affects expression EXP 6480464 Benzo(a)pyrene affects the expression of SQSTM1 protein CTD PMID:32619457 berberine increases expression ISO RGD:736484 6480464 Berberine results in increased expression of SQSTM1 protein CTD PMID:36070022 beta-naphthoflavone increases expression ISO RGD:736484 6480464 beta-Naphthoflavone results in increased expression of SQSTM1 mRNA CTD PMID:32151702 beta-thujaplicin decreases expression ISO RGD:736485 6480464 beta-thujaplicin results in decreased expression of SQSTM1 protein CTD PMID:25044443 bexarotene increases expression EXP 6480464 bexarotene results in increased expression of SQSTM1 mRNA CTD PMID:16648578 bicalutamide increases expression ISO RGD:736484 6480464 bicalutamide results in increased expression of SQSTM1 mRNA CTD PMID:15638997 bis(2-chloroethyl) sulfide increases phosphorylation ISO RGD:736484 6480464 Mustard Gas results in increased phosphorylation of SQSTM1 protein CTD PMID:19845377 bis(2-ethylhexyl) phthalate increases expression ISO RGD:736484 6480464 Diethylhexyl Phthalate analog results in increased expression of SQSTM1 mRNA more ... CTD PMID:34822940 bisphenol A decreases expression ISO RGD:736484 6480464 bisphenol A results in decreased expression of SQSTM1 mRNA, bisphenol A results in decreased expression of SQSTM1 protein CTD PMID:16474171 , PMID:34186270 bisphenol A decreases expression EXP 6480464 bisphenol A analog results in decreased expression of SQSTM1 mRNA, bisphenol A analog results in decreased expression of SQSTM1 protein CTD PMID:35427877 bisphenol A multiple interactions EXP 6480464 [bisphenol A co-treated with bisphenol F co-treated with bis(4-hydroxyphenyl)sulfone] results in decreased expression of SQSTM1 mRNA CTD PMID:36041667 bisphenol A increases expression EXP 6480464 bisphenol A results in increased expression of SQSTM1 protein CTD PMID:31551937 bisphenol A multiple interactions ISO RGD:736485 6480464 [bisphenol A co-treated with 9-(6-aminopyridin-3-yl)-1-(3-(trifluoromethyl)phenyl)benzo(h)(1 more ... CTD PMID:34186417 bisphenol A increases expression ISO RGD:736484 6480464 bisphenol A results in increased expression of SQSTM1 mRNA, bisphenol A results in increased expression of SQSTM1 protein CTD PMID:29275510 , PMID:34281243 bisphenol A affects expression ISO RGD:736484 6480464 bisphenol A affects the expression of SQSTM1 mRNA CTD PMID:30903817 bisphenol A multiple interactions ISO RGD:736484 6480464 [3-methyladenine co-treated with bisphenol A] results in increased expression of SQSTM1 protein, [INS protein co-treated with Dexamethasone co-treated with 1-Methyl-3-isobutylxanthine co-treated with Indomethacin co-treated with bisphenol A] results in decreased expression of SQSTM1 mRNA CTD PMID:28628672 , PMID:34281243 bisphenol A increases methylation EXP 6480464 bisphenol A results in increased methylation of SQSTM1 gene CTD PMID:28505145 bisphenol A affects expression EXP 6480464 bisphenol A affects the expression of SQSTM1 mRNA CTD PMID:25181051 , PMID:30903817 bisphenol A increases expression ISO RGD:736485 6480464 bisphenol A results in increased expression of SQSTM1 mRNA, bisphenol A results in increased expression of SQSTM1 protein CTD PMID:12233820 more ... bisphenol F multiple interactions EXP 6480464 [bisphenol A co-treated with bisphenol F co-treated with bis(4-hydroxyphenyl)sulfone] results in decreased expression of SQSTM1 mRNA CTD PMID:36041667 bortezomib increases expression ISO RGD:736484 6480464 Bortezomib results in increased expression of SQSTM1 mRNA CTD PMID:20977926 bortezomib increases expression EXP 6480464 Bortezomib results in increased expression of SQSTM1 mRNA CTD PMID:20830808 brazilin decreases expression ISO RGD:736484 6480464 brazilin results in decreased expression of SQSTM1 protein CTD PMID:28063998 brazilin multiple interactions ISO RGD:736484 6480464 Acetylcysteine inhibits the reaction [brazilin results in decreased expression of SQSTM1 protein], RELA protein promotes the reaction [brazilin results in decreased expression of SQSTM1 protein] CTD PMID:28063998 Brusatol multiple interactions EXP 6480464 brusatol inhibits the reaction [[Cadmium Chloride results in increased abundance of Cadmium] which results in increased expression of SQSTM1 protein] CTD PMID:34695510 butane-2,3-dione increases expression ISO RGD:736484 6480464 Diacetyl results in increased expression of SQSTM1 protein CTD PMID:34031698 butyric acid decreases expression ISO RGD:736484 6480464 Butyric Acid results in decreased expression of SQSTM1 mRNA CTD PMID:34581912 cadmium atom increases expression ISO RGD:736484 6480464 Cadmium results in increased expression of SQSTM1 mRNA CTD PMID:21120746 cadmium atom multiple interactions ISO RGD:736485 6480464 3-(2 more ... CTD PMID:31862506 more ... cadmium atom multiple interactions ISO RGD:736484 6480464 3-methyladenine inhibits the reaction [[Cadmium Chloride results in increased abundance of Cadmium] which results in decreased expression of SQSTM1 protein] more ... CTD PMID:31319114 more ... cadmium atom decreases expression EXP 6480464 Cadmium results in decreased expression of SQSTM1 protein CTD PMID:27658547 , PMID:32693121 cadmium atom multiple interactions EXP 6480464 [Cadmium Chloride results in increased abundance of Cadmium] which results in increased expression of SQSTM1 protein more ... CTD PMID:27658547 more ... cadmium atom increases expression ISO RGD:736485 6480464 Cadmium results in increased expression of SQSTM1 mRNA CTD PMID:24067728 cadmium dichloride increases expression EXP 6480464 Cadmium Chloride results in increased expression of SQSTM1 mRNA CTD PMID:22110744 cadmium dichloride multiple interactions EXP 6480464 [Cadmium Chloride results in increased abundance of Cadmium] which results in increased expression of SQSTM1 protein more ... CTD PMID:34695510 cadmium dichloride decreases expression ISO RGD:736484 6480464 Cadmium Chloride results in decreased expression of SQSTM1 protein CTD PMID:33127495 cadmium dichloride decreases expression EXP 6480464 Cadmium Chloride results in decreased expression of SQSTM1 protein CTD PMID:29218509 , PMID:33127495 cadmium dichloride multiple interactions ISO RGD:736484 6480464 3-methyladenine inhibits the reaction [[Cadmium Chloride results in increased abundance of Cadmium] which results in decreased expression of SQSTM1 protein] more ... CTD PMID:31319114 more ... cadmium dichloride decreases expression ISO RGD:736485 6480464 Cadmium Chloride results in decreased expression of SQSTM1 mRNA, Cadmium Chloride results in decreased expression of SQSTM1 protein CTD PMID:29486218 , PMID:35843418 cadmium dichloride increases expression ISO RGD:736484 6480464 Cadmium Chloride results in increased expression of SQSTM1 mRNA, Cadmium Chloride results in increased expression of SQSTM1 protein CTD PMID:25596134 , PMID:34580807 cadmium dichloride increases expression ISO RGD:736485 6480464 Cadmium Chloride results in increased expression of SQSTM1 mRNA, Cadmium Chloride results in increased expression of SQSTM1 protein CTD PMID:11958953 more ... cadmium dichloride multiple interactions ISO RGD:736485 6480464 3-(2 more ... CTD PMID:11958953 more ... caffeine increases expression EXP 6480464 Caffeine results in increased expression of SQSTM1 mRNA CTD PMID:20864626 caffeine affects phosphorylation ISO RGD:736484 6480464 Caffeine affects the phosphorylation of SQSTM1 protein CTD PMID:35688186 caffeine multiple interactions ISO RGD:736484 6480464 Caffeine inhibits the reaction [Doxorubicin results in increased degradation of SQSTM1 protein] CTD PMID:22927544 caffeine decreases expression ISO RGD:736484 6480464 Caffeine results in decreased expression of SQSTM1 protein CTD PMID:21081844 calcium atom affects expression EXP 6480464 Calcium affects the expression of SQSTM1 mRNA CTD PMID:15913539 calcium(0) affects expression EXP 6480464 Calcium affects the expression of SQSTM1 mRNA CTD PMID:15913539 camptothecin multiple interactions ISO RGD:736484 6480464 ATG5 mutant form inhibits the reaction [Camptothecin results in increased degradation of SQSTM1 protein], Camptothecin inhibits the reaction [Cannabidiol results in increased expression of SQSTM1 mRNA] CTD PMID:22927544 , PMID:34302491 camptothecin increases degradation ISO RGD:736484 6480464 Camptothecin results in increased degradation of SQSTM1 protein CTD PMID:22927544 cannabidiol increases expression ISO RGD:736485 6480464 Cannabidiol results in increased expression of SQSTM1 mRNA CTD PMID:21542829 cannabidiol increases expression ISO RGD:736484 6480464 Cannabidiol results in increased expression of SQSTM1 mRNA, Cannabidiol results in increased expression of SQSTM1 protein CTD PMID:31518892 , PMID:34302491 cannabidiol decreases expression ISO RGD:736484 6480464 Cannabidiol results in decreased expression of SQSTM1 mRNA, Cannabidiol results in decreased expression of SQSTM1 protein CTD PMID:27769052 , PMID:31801206 cannabidiol multiple interactions ISO RGD:736484 6480464 [Dronabinol co-treated with Cannabidiol] results in decreased expression of SQSTM1 protein more ... CTD PMID:27769052 , PMID:34302491 carbamazepine affects expression ISO RGD:736484 6480464 Carbamazepine affects the expression of SQSTM1 mRNA CTD PMID:25979313 carbamazepine multiple interactions EXP 6480464 [Dietary Fats co-treated with Streptozocin co-treated with Carbamazepine] results in decreased expression of SQSTM1 protein CTD PMID:35786680 carbon disulfide multiple interactions EXP 6480464 Carbon Disulfide results in increased expression of and results in increased phosphorylation of SQSTM1 protein CTD PMID:27530093 carbon disulfide increases expression ISO RGD:736485 6480464 Carbon Disulfide results in increased expression of SQSTM1 mRNA, Carbon Disulfide results in increased expression of SQSTM1 protein CTD PMID:31369747 carbon disulfide multiple interactions ISO RGD:736485 6480464 N-carbamylglutamate inhibits the reaction [Carbon Disulfide results in increased expression of SQSTM1 mRNA], N-carbamylglutamate inhibits the reaction [Carbon Disulfide results in increased expression of SQSTM1 protein] CTD PMID:31369747 carbon nanotube increases expression ISO RGD:736484 6480464 Nanotubes, Carbon results in increased expression of SQSTM1 protein CTD PMID:24389112 carbon nanotube increases expression ISO RGD:736485 6480464 Nanotubes, Carbon results in increased expression of SQSTM1 mRNA CTD PMID:25554681 carglumic acid multiple interactions ISO RGD:736485 6480464 N-carbamylglutamate inhibits the reaction [Carbon Disulfide results in increased expression of SQSTM1 mRNA], N-carbamylglutamate inhibits the reaction [Carbon Disulfide results in increased expression of SQSTM1 protein] CTD PMID:31369747 CCCP multiple interactions ISO RGD:736484 6480464 [[Carbonyl Cyanide m-Chlorophenyl Hydrazone inhibits the reaction [SQSTM1 protein binds to KEAP1 protein]] promotes the reaction [KEAP1 protein binds to NFE2L2 protein]] which results in decreased activity of NFE2L2 protein more ... CTD PMID:30715550 , PMID:34481905 celastrol decreases expression EXP 6480464 celastrol results in decreased expression of SQSTM1 protein CTD PMID:32470352 celastrol multiple interactions EXP 6480464 N-(1 more ... CTD PMID:32470352 celecoxib multiple interactions ISO RGD:736484 6480464 [Celecoxib co-treated with ABT-737] results in decreased expression of SQSTM1 protein CTD PMID:20104024 cerium trichloride multiple interactions ISO RGD:736484 6480464 [cerous chloride co-treated with lanthanum chloride] results in increased expression of SQSTM1 mRNA CTD PMID:28954213 cerium trichloride affects expression ISO RGD:736484 6480464 cerous chloride affects the expression of SQSTM1 mRNA CTD PMID:28954213 chenodeoxycholic acid increases expression ISO RGD:736485 6480464 Chenodeoxycholic Acid results in increased expression of SQSTM1 protein CTD PMID:24189133 chenodeoxycholic acid multiple interactions ISO RGD:736484 6480464 [Atazanavir Sulfate co-treated with Glycochenodeoxycholic Acid co-treated with Deoxycholic Acid co-treated with Chenodeoxycholic Acid co-treated with Glycodeoxycholic Acid co-treated with Glycocholic Acid] results in increased expression of SQSTM1 mRNA more ... CTD PMID:32152650 CHIR 99021 multiple interactions ISO RGD:736485 6480464 Chir 99021 inhibits the reaction [1-Methyl-4-phenylpyridinium results in increased expression of SQSTM1 protein] CTD PMID:30165626 CHIR 99021 multiple interactions ISO RGD:736484 6480464 [4-(2-(5 more ... CTD PMID:34480604 chloroacetaldehyde increases expression ISO RGD:736484 6480464 chloroacetaldehyde results in increased expression of SQSTM1 mRNA CTD PMID:25596134 chlorogenic acid multiple interactions ISO RGD:736484 6480464 Chlorogenic Acid inhibits the reaction [Acetaminophen results in decreased expression of SQSTM1 protein] CTD PMID:29136249 chloropicrin increases expression ISO RGD:736484 6480464 chloropicrin results in increased expression of SQSTM1 mRNA CTD PMID:24211530 , PMID:28476498 chloropicrin affects expression ISO RGD:736484 6480464 chloropicrin affects the expression of SQSTM1 mRNA CTD PMID:26352163 chloroquine multiple interactions ISO RGD:736484 6480464 Chloroquine inhibits the reaction [[Simvastatin co-treated with Metformin] results in decreased expression of SQSTM1 protein] more ... CTD PMID:21858812 more ... chloroquine increases expression ISO RGD:736485 6480464 Chloroquine results in increased expression of SQSTM1 protein CTD PMID:25884947 more ... chloroquine increases expression EXP 6480464 Chloroquine results in increased expression of SQSTM1 protein CTD PMID:31586597 chloroquine increases expression ISO RGD:736484 6480464 Chloroquine results in increased expression of SQSTM1 protein CTD PMID:21858812 more ... chloroquine multiple interactions ISO RGD:736485 6480464 [bisphenol A co-treated with Chloroquine] results in increased expression of SQSTM1 protein more ... CTD PMID:24751611 more ... chloroquine multiple interactions EXP 6480464 Chloroquine inhibits the reaction [cadmium acetate results in decreased expression of SQSTM1 protein] more ... CTD PMID:27658547 more ... chlorpyrifos multiple interactions EXP 6480464 STAT1 protein affects the reaction [Chlorpyrifos results in increased expression of SQSTM1 protein] CTD PMID:29859868 chlorpyrifos increases expression EXP 6480464 Chlorpyrifos results in increased expression of SQSTM1 protein CTD PMID:29859868 cholesterol increases expression ISO RGD:736484 6480464 Cholesterol results in increased expression of SQSTM1 protein CTD PMID:28275691 cholesterol multiple interactions ISO RGD:736485 6480464 Cholesterol inhibits the reaction [Cadmium Chloride results in decreased expression of SQSTM1 protein] CTD PMID:29486218 cholic acid increases expression ISO RGD:736485 6480464 Cholic Acid results in increased expression of SQSTM1 protein CTD PMID:24189133 chromium(6+) multiple interactions ISO RGD:736484 6480464 chromium hexavalent ion results in increased expression of and results in increased phosphorylation of SQSTM1 protein CTD PMID:30715550 ciglitazone multiple interactions ISO RGD:736484 6480464 [ciglitazone binds to PPARG protein] which results in increased expression of SQSTM1 mRNA CTD PMID:16197558 ciprofibrate increases expression ISO RGD:736485 6480464 ciprofibrate results in increased expression of SQSTM1 mRNA CTD PMID:12771043 cisplatin multiple interactions ISO RGD:736484 6480464 3-methyladenine affects the reaction [ginsenoside Rg3 affects the reaction [Cisplatin affects the expression of SQSTM1 protein]] more ... CTD PMID:21858171 more ... cisplatin decreases expression ISO RGD:736485 6480464 Cisplatin results in decreased expression of SQSTM1 protein CTD PMID:31220555 cisplatin multiple interactions ISO RGD:736485 6480464 bafilomycin B1 promotes the reaction [Cisplatin results in increased expression of SQSTM1 protein] more ... CTD PMID:31220555 more ... cisplatin increases expression EXP 6480464 Cisplatin results in increased expression of SQSTM1 protein CTD PMID:30291731 , PMID:30842369 cisplatin multiple interactions EXP 6480464 astragaloside A inhibits the reaction [Cisplatin results in increased expression of SQSTM1 protein] CTD PMID:30842369 cisplatin decreases expression ISO RGD:736484 6480464 Cisplatin results in decreased expression of SQSTM1 protein CTD PMID:25979647 more ... cisplatin affects expression ISO RGD:736484 6480464 Cisplatin affects the expression of SQSTM1 mRNA, Cisplatin affects the expression of SQSTM1 protein CTD PMID:23300844 , PMID:34423507 cisplatin increases expression ISO RGD:736485 6480464 Cisplatin results in increased expression of SQSTM1 protein CTD PMID:32738330 , PMID:34423507 cisplatin decreases response to substance ISO RGD:736484 6480464 SQSTM1 protein results in decreased susceptibility to Cisplatin CTD PMID:21371883 cisplatin increases expression ISO RGD:736484 6480464 Cisplatin results in increased expression of SQSTM1 mRNA, Cisplatin results in increased expression of SQSTM1 protein CTD PMID:21184746 more ... Citreoviridin multiple interactions ISO RGD:736485 6480464 Sodium Selenite inhibits the reaction [citreoviridin results in decreased expression of SQSTM1 protein], Thiamine inhibits the reaction [citreoviridin results in decreased expression of SQSTM1 protein] CTD PMID:31419397 Citreoviridin multiple interactions EXP 6480464 Rosiglitazone inhibits the reaction [citreoviridin results in decreased expression of SQSTM1 protein] more ... CTD PMID:31419397 Citreoviridin decreases expression EXP 6480464 citreoviridin results in decreased expression of SQSTM1 protein CTD PMID:31419397 Citreoviridin decreases expression ISO RGD:736485 6480464 citreoviridin results in decreased expression of SQSTM1 protein CTD PMID:31419397 clofibrate multiple interactions ISO RGD:736485 6480464 [Clofibrate co-treated with Acetaminophen] affects the expression of SQSTM1 mRNA, PPARA affects the reaction [[Clofibrate co-treated with Acetaminophen] affects the expression of SQSTM1 mRNA] CTD PMID:17585979 clozapine increases expression ISO RGD:736484 6480464 Clozapine results in increased expression of SQSTM1 protein CTD PMID:36482696 cobalt atom multiple interactions ISO RGD:736484 6480464 [tungsten carbide co-treated with Cobalt] results in increased expression of SQSTM1 mRNA CTD PMID:18078969 cobalt dichloride increases expression ISO RGD:736484 6480464 cobaltous chloride results in increased expression of SQSTM1 mRNA CTD PMID:19320972 , PMID:19376846 cobalt dichloride increases expression EXP 6480464 cobaltous chloride results in increased expression of SQSTM1 mRNA CTD PMID:24386269 cocaine decreases expression ISO RGD:736485 6480464 Cocaine results in decreased expression of SQSTM1 protein CTD PMID:31494168 coenzyme Q10 multiple interactions ISO RGD:736485 6480464 Chloroquine inhibits the reaction [coenzyme Q10 promotes the reaction [Acetaminophen results in decreased expression of SQSTM1 protein]], coenzyme Q10 promotes the reaction [Acetaminophen results in decreased expression of SQSTM1 protein] CTD PMID:33271250 colforsin daropate hydrochloride increases degradation ISO RGD:736484 6480464 Colforsin results in increased degradation of SQSTM1 protein CTD PMID:25943029 colistin increases degradation EXP 6480464 Colistin results in increased degradation of SQSTM1 protein CTD PMID:28842171 colistin multiple interactions EXP 6480464 Anisomycin promotes the reaction [Colistin results in increased degradation of SQSTM1 protein], pyrazolanthrone inhibits the reaction [Colistin results in increased degradation of SQSTM1 protein] CTD PMID:28842171 copper atom multiple interactions ISO RGD:736484 6480464 [Chelating Agents binds to Copper] which results in increased expression of SQSTM1 mRNA more ... CTD PMID:20971185 more ... copper atom multiple interactions ISO RGD:736485 6480464 [Copper Sulfate results in increased abundance of Copper] which results in increased expression of SQSTM1 mRNA, [Copper Sulfate results in increased abundance of Copper] which results in increased expression of SQSTM1 protein CTD PMID:31491480 copper(0) multiple interactions ISO RGD:736484 6480464 [Chelating Agents binds to Copper] which results in increased expression of SQSTM1 mRNA more ... CTD PMID:20971185 more ... copper(0) multiple interactions ISO RGD:736485 6480464 [Copper Sulfate results in increased abundance of Copper] which results in increased expression of SQSTM1 mRNA, [Copper Sulfate results in increased abundance of Copper] which results in increased expression of SQSTM1 protein CTD PMID:31491480 copper(II) chloride increases expression ISO RGD:736484 6480464 cupric chloride results in increased expression of SQSTM1 mRNA CTD PMID:17211630 copper(II) chloride multiple interactions ISO RGD:736485 6480464 Acetylcysteine inhibits the reaction [cupric chloride results in increased expression of SQSTM1 protein], PP242 inhibits the reaction [cupric chloride results in increased expression of SQSTM1 protein] CTD PMID:32512069 copper(II) chloride increases expression ISO RGD:736485 6480464 cupric chloride results in increased expression of SQSTM1 protein CTD PMID:23313662 , PMID:32512069 copper(II) sulfate increases expression ISO RGD:736484 6480464 Copper Sulfate results in increased expression of SQSTM1 mRNA CTD PMID:19549813 copper(II) sulfate multiple interactions ISO RGD:736485 6480464 [Copper Sulfate results in increased abundance of Copper] which results in increased expression of SQSTM1 mRNA, [Copper Sulfate results in increased abundance of Copper] which results in increased expression of SQSTM1 protein CTD PMID:31491480 corosolic acid multiple interactions ISO RGD:736485 6480464 corosolic acid inhibits the reaction [Doxorubicin results in increased expression of SQSTM1 protein] CTD PMID:34296331 corosolic acid multiple interactions EXP 6480464 corosolic acid inhibits the reaction [Doxorubicin results in increased expression of SQSTM1 protein], TFEB protein promotes the reaction [corosolic acid inhibits the reaction [Doxorubicin results in increased expression of SQSTM1 protein]] CTD PMID:34296331 cortisol multiple interactions ISO RGD:736484 6480464 [4-(2-(5 more ... CTD PMID:34480604 Corynoxine B multiple interactions ISO RGD:736484 6480464 corynoxine B affects the reaction [manganese chloride affects the expression of SQSTM1 protein] CTD PMID:30578841 coumarin affects phosphorylation ISO RGD:736484 6480464 coumarin affects the phosphorylation of SQSTM1 protein CTD PMID:35688186 coumestrol multiple interactions ISO RGD:736484 6480464 [Coumestrol co-treated with 2, 3-bis(3'-hydroxybenzyl)butyrolactone] results in decreased expression of SQSTM1 mRNA CTD PMID:19167446 coumestrol decreases expression ISO RGD:736484 6480464 Coumestrol results in decreased expression of SQSTM1 mRNA CTD PMID:19167446 crocidolite asbestos increases expression ISO RGD:736484 6480464 Asbestos, Crocidolite results in increased expression of SQSTM1 mRNA CTD PMID:18687144 crocidolite asbestos affects expression ISO RGD:736484 6480464 Asbestos, Crocidolite affects the expression of SQSTM1 mRNA CTD PMID:17331233 , PMID:25757056 Cryptotanshinone decreases expression ISO RGD:736484 6480464 cryptotanshinone results in decreased expression of SQSTM1 protein CTD PMID:28600121 Cryptotanshinone multiple interactions ISO RGD:736484 6480464 Chloroquine inhibits the reaction [cryptotanshinone results in decreased expression of SQSTM1 protein] CTD PMID:28600121 cucurbitacin E multiple interactions ISO RGD:736484 6480464 Acetylcysteine inhibits the reaction [cucurbitacin E results in increased expression of SQSTM1 protein] CTD PMID:27106530 cucurbitacin E increases expression ISO RGD:736484 6480464 cucurbitacin E results in increased expression of SQSTM1 protein CTD PMID:27106530 curcumin decreases expression ISO RGD:736484 6480464 Curcumin results in decreased expression of SQSTM1 protein CTD PMID:34634291 Curcumol multiple interactions EXP 6480464 curcumol inhibits the reaction [VEGFA protein results in decreased expression of SQSTM1 mRNA] more ... CTD PMID:33549628 cycloheximide decreases expression ISO RGD:736484 6480464 Cycloheximide results in decreased expression of SQSTM1 protein CTD PMID:31781319 cycloheximide multiple interactions ISO RGD:736484 6480464 [sodium arsenite results in increased abundance of arsenite] inhibits the reaction [Cycloheximide results in decreased expression of SQSTM1 protein], Cycloheximide promotes the reaction [pterostilbene inhibits the reaction [Ethanol results in increased expression of SQSTM1 protein]] CTD PMID:31781319 , PMID:34405320 cyclosporin A increases expression ISO RGD:736485 6480464 Cyclosporine results in increased expression of SQSTM1 mRNA CTD PMID:19770486 cyclosporin A multiple interactions ISO RGD:736484 6480464 [Cyclosporine co-treated with Glycochenodeoxycholic Acid co-treated with Deoxycholic Acid co-treated with Chenodeoxycholic Acid co-treated with Glycodeoxycholic Acid co-treated with Glycocholic Acid] results in increased expression of SQSTM1 mRNA, Cyclosporine inhibits the reaction [quinone results in decreased expression of SQSTM1 protein] CTD PMID:29567065 , PMID:32152650 cyclosporin A decreases expression ISO RGD:736485 6480464 Cyclosporine results in decreased expression of SQSTM1 protein CTD PMID:33689844 cyclosporin A increases expression EXP 6480464 Cyclosporine results in increased expression of SQSTM1 mRNA CTD PMID:25596134 cyclosporin A increases expression ISO RGD:736484 6480464 Cyclosporine results in increased expression of SQSTM1 mRNA CTD PMID:20106945 more ... cyfluthrin increases expression ISO RGD:736484 6480464 cyfluthrin results in increased expression of SQSTM1 mRNA CTD PMID:31330490 cyfluthrin multiple interactions ISO RGD:736484 6480464 Melatonin inhibits the reaction [cyfluthrin results in increased expression of SQSTM1 mRNA] CTD PMID:31330490 cylindrospermopsin increases expression ISO RGD:736485 6480464 cylindrospermopsin results in increased expression of SQSTM1 mRNA CTD PMID:20936652 cypermethrin increases expression ISO RGD:736484 6480464 cypermethrin results in increased expression of SQSTM1 mRNA CTD PMID:27704156 D-glucose increases expression EXP 6480464 Glucose results in increased expression of SQSTM1 protein CTD PMID:28713934 more ... D-glucose increases expression ISO RGD:736484 6480464 Glucose deficiency results in increased expression of SQSTM1 protein CTD PMID:34580807 D-glucose increases expression ISO RGD:736485 6480464 Glucose results in increased expression of SQSTM1 protein CTD PMID:30459625 D-glucose multiple interactions ISO RGD:736485 6480464 HU 308 inhibits the reaction [Glucose results in increased expression of SQSTM1 protein] CTD PMID:30459625 D-glucose decreases expression ISO RGD:736484 6480464 Glucose deficiency results in decreased expression of SQSTM1 protein CTD PMID:29649567 D-glucose multiple interactions EXP 6480464 3-methyladenine inhibits the reaction [N-(1 more ... CTD PMID:28713934 more ... dactolisib multiple interactions ISO RGD:736484 6480464 bafilomycin A1 inhibits the reaction [dactolisib results in decreased expression of SQSTM1 protein], Chloroquine inhibits the reaction [dactolisib results in decreased expression of SQSTM1 protein] CTD PMID:23151917 , PMID:23651616 dactolisib decreases expression ISO RGD:736484 6480464 dactolisib results in decreased expression of SQSTM1 protein CTD PMID:23151917 , PMID:23651616 dapagliflozin multiple interactions EXP 6480464 [dapagliflozin co-treated with Atorvastatin] inhibits the reaction [[Dietary Fats co-treated with Fructose] results in increased expression of SQSTM1 protein], dapagliflozin inhibits the reaction [Trinitrobenzenesulfonic Acid results in increased expression of SQSTM1 protein] CTD PMID:33412153 , PMID:34939712 DDT increases expression ISO RGD:736484 6480464 DDT results in increased expression of SQSTM1 mRNA CTD PMID:26198647 deguelin increases expression ISO RGD:736484 6480464 deguelin results in increased expression of SQSTM1 mRNA CTD PMID:33512557 deoxycholic acid multiple interactions ISO RGD:736484 6480464 [Atazanavir Sulfate co-treated with Glycochenodeoxycholic Acid co-treated with Deoxycholic Acid co-treated with Chenodeoxycholic Acid co-treated with Glycodeoxycholic Acid co-treated with Glycocholic Acid] results in increased expression of SQSTM1 mRNA more ... CTD PMID:32152650 deoxynivalenol increases expression ISO RGD:736484 6480464 deoxynivalenol results in increased expression of SQSTM1 mRNA CTD PMID:31863870 desferrioxamine B increases expression ISO RGD:736484 6480464 Deferoxamine results in increased expression of SQSTM1 protein CTD PMID:25301941 desferrioxamine B multiple interactions ISO RGD:736484 6480464 [Copper co-treated with Deferoxamine] results in increased expression of SQSTM1 protein more ... CTD PMID:25301941 , PMID:32283200 dexamethasone multiple interactions ISO RGD:736484 6480464 5-amino-7-(cyclohexylamino)-1-ethyl-6-fluoro-4-oxo-1 more ... CTD PMID:23111315 more ... dexamethasone decreases expression ISO RGD:736484 6480464 Dexamethasone results in decreased expression of SQSTM1 protein CTD PMID:33359579 dexamethasone decreases expression EXP 6480464 Dexamethasone results in decreased expression of SQSTM1 protein CTD PMID:33359579 dextran sulfate multiple interactions ISO RGD:736485 6480464 2-methyl-2H-pyrazole-3-carboxylic acid (2-methyl-4-o-tolylazophenyl)amide inhibits the reaction [[Dextran Sulfate co-treated with alpinetin] results in decreased expression of SQSTM1 protein] more ... CTD PMID:27611972 more ... dextran sulfate multiple interactions ISO RGD:736484 6480464 dorsomorphin inhibits the reaction [Nicotine promotes the reaction [Dextran Sulfate results in decreased expression of SQSTM1 protein]], Nicotine promotes the reaction [Dextran Sulfate results in decreased expression of SQSTM1 protein] CTD PMID:31926917 dextran sulfate decreases expression ISO RGD:736484 6480464 Dextran Sulfate results in decreased expression of SQSTM1 protein CTD PMID:31926917 dextran sulfate decreases expression ISO RGD:736485 6480464 Dextran Sulfate results in decreased expression of SQSTM1 protein CTD PMID:31926917 diarsenic trioxide decreases expression EXP 6480464 Arsenic Trioxide results in decreased expression of SQSTM1 protein CTD PMID:29111283 diarsenic trioxide affects expression ISO RGD:736485 6480464 Arsenic Trioxide affects the expression of SQSTM1 protein CTD PMID:33462182 diarsenic trioxide affects expression ISO RGD:736484 6480464 Arsenic Trioxide affects the expression of SQSTM1 protein CTD PMID:33462182 diarsenic trioxide multiple interactions EXP 6480464 ferrostatin-1 inhibits the reaction [Arsenic Trioxide results in increased expression of SQSTM1 protein] more ... CTD PMID:29111283 more ... diarsenic trioxide increases expression ISO RGD:736485 6480464 Arsenic Trioxide results in increased expression of SQSTM1 mRNA, Arsenic Trioxide results in increased expression of SQSTM1 protein CTD PMID:24801902 more ... diarsenic trioxide multiple interactions ISO RGD:736485 6480464 3-methyladenine inhibits the reaction [Arsenic Trioxide results in decreased expression of SQSTM1 protein] more ... CTD PMID:30237538 more ... diarsenic trioxide increases expression ISO RGD:736484 6480464 Arsenic Trioxide results in increased expression of SQSTM1 mRNA, Arsenic Trioxide results in increased expression of SQSTM1 protein CTD PMID:20200477 more ... diarsenic trioxide increases expression EXP 6480464 Arsenic Trioxide results in increased expression of SQSTM1 protein CTD PMID:30551535 more ... diarsenic trioxide decreases response to substance ISO RGD:736484 6480464 SQSTM1 protein results in decreased susceptibility to Arsenic Trioxide CTD PMID:20707922 diarsenic trioxide decreases expression ISO RGD:736485 6480464 Arsenic Trioxide results in decreased expression of SQSTM1 protein CTD PMID:29111283 more ... diarsenic trioxide decreases expression ISO RGD:736484 6480464 Arsenic Trioxide results in decreased expression of SQSTM1 protein CTD PMID:29307831 more ... diarsenic trioxide multiple interactions ISO RGD:736484 6480464 3-methyladenine inhibits the reaction [Arsenic Trioxide results in decreased expression of SQSTM1 protein] more ... CTD PMID:15894607 more ... diarsenic trioxide affects binding ISO RGD:736484 6480464 Arsenic Trioxide binds to SQSTM1 protein CTD PMID:30237564 diazinon increases methylation ISO RGD:736484 6480464 Diazinon results in increased methylation of SQSTM1 gene CTD PMID:22964155 diazinon increases expression ISO RGD:736484 6480464 Diazinon results in increased expression of SQSTM1 mRNA CTD PMID:26198647 diazinon affects expression EXP 6480464 Diazinon affects the expression of SQSTM1 mRNA CTD PMID:22546817 dibenzofuran decreases expression ISO RGD:736484 6480464 dibenzofuran results in decreased expression of SQSTM1 protein CTD PMID:22173198 dibutyl phthalate decreases expression ISO RGD:736485 6480464 Dibutyl Phthalate results in decreased expression of SQSTM1 protein CTD PMID:26804720 Didecyldimethylammonium increases expression ISO RGD:736484 6480464 didecyldimethylammonium results in increased expression of SQSTM1 protein CTD PMID:32763356 dieldrin affects expression EXP 6480464 Dieldrin affects the expression of SQSTM1 mRNA CTD PMID:22546817 diethyl maleate increases expression ISO RGD:736485 6480464 diethyl maleate results in increased expression of SQSTM1 mRNA CTD PMID:25270620 diethyl maleate increases expression ISO RGD:736484 6480464 diethyl maleate results in increased expression of SQSTM1 mRNA CTD PMID:33545341 , PMID:34480604 dimethyl fumarate multiple interactions ISO RGD:736485 6480464 NFE2L2 protein affects the reaction [Dimethyl Fumarate results in increased expression of SQSTM1 protein] CTD PMID:29950142 dimethyl fumarate increases expression ISO RGD:736485 6480464 Dimethyl Fumarate results in increased expression of SQSTM1 protein CTD PMID:29950142 dinitrogen decreases expression ISO RGD:736484 6480464 Nitrogen deficiency results in decreased expression of SQSTM1 protein CTD PMID:27629431 dinitrogen multiple interactions ISO RGD:736484 6480464 bafilomycin A inhibits the reaction [Nitrogen deficiency results in decreased expression of SQSTM1 protein], Nitrogen deficiency promotes the reaction [ATG13 protein results in decreased expression of SQSTM1 protein] CTD PMID:27629431 dioxygen decreases expression ISO RGD:736484 6480464 Oxygen deficiency results in decreased expression of SQSTM1 mRNA CTD PMID:25596134 dioxygen multiple interactions EXP 6480464 [[Oxygen deficiency co-treated with Blood Glucose deficiency] results in increased susceptibility to SB 239063] which results in increased expression of SQSTM1 protein CTD PMID:26116440 dioxygen multiple interactions ISO RGD:736485 6480464 [[Oxygen deficiency co-treated with Blood Glucose deficiency] co-treated with [Oxygen co-treated with Blood Glucose]] results in decreased expression of SQSTM1 protein more ... CTD PMID:28477916 more ... dipotassium bis[mu-tartrato(4-)]diantimonate(2-) trihydrate multiple interactions ISO RGD:736484 6480464 [Antimony Potassium Tartrate results in increased abundance of antimonite] which results in increased expression of SQSTM1 mRNA CTD PMID:32076005 disodium selenite increases expression ISO RGD:736484 6480464 Sodium Selenite results in increased expression of SQSTM1 mRNA CTD PMID:24383545 disodium selenite multiple interactions ISO RGD:736485 6480464 Sodium Selenite inhibits the reaction [citreoviridin results in decreased expression of SQSTM1 protein] CTD PMID:31419397 disodium selenite multiple interactions ISO RGD:736484 6480464 [Sodium Selenite co-treated with (1 more ... CTD PMID:28757135 disodium selenite multiple interactions EXP 6480464 Sodium Selenite inhibits the reaction [citreoviridin results in decreased expression of SQSTM1 protein] CTD PMID:31419397 diuron increases expression EXP 6480464 Diuron results in increased expression of SQSTM1 mRNA CTD PMID:21551480 dorsomorphin decreases expression ISO RGD:736484 6480464 dorsomorphin results in decreased expression of SQSTM1 protein CTD PMID:31900833 dorsomorphin multiple interactions ISO RGD:736484 6480464 [NOG protein co-treated with mercuric bromide co-treated with dorsomorphin co-treated with 4-(5-benzo(1 more ... CTD PMID:27188386 more ... dorsomorphin multiple interactions EXP 6480464 dorsomorphin inhibits the reaction [ADIPOQ protein inhibits the reaction [Rotenone results in increased expression of SQSTM1 protein]], dorsomorphin promotes the reaction [Rotenone results in increased expression of SQSTM1 protein] CTD PMID:33137417 dorsomorphin multiple interactions ISO RGD:736485 6480464 dorsomorphin inhibits the reaction [graphene oxide results in decreased expression of SQSTM1 protein] CTD PMID:32430275 doxorubicin increases expression ISO RGD:736484 6480464 Doxorubicin results in increased expression of SQSTM1 mRNA, Doxorubicin results in increased expression of SQSTM1 protein CTD PMID:21184746 , PMID:29803840 doxorubicin decreases expression ISO RGD:736485 6480464 Doxorubicin results in decreased expression of SQSTM1 protein CTD PMID:36195186 doxorubicin multiple interactions EXP 6480464 4-(((4-carboxybutyl) (2- (5-fluoro-2-((4'-(trifluoromethyl) biphenyl-4-yl)methoxy)phenyl)ethyl) amino)methyl)benzoic acid inhibits the reaction [Doxorubicin results in increased expression of SQSTM1 protein] more ... CTD PMID:32525084 more ... doxorubicin affects expression ISO RGD:736485 6480464 Doxorubicin affects the expression of SQSTM1 protein CTD PMID:35134463 doxorubicin multiple interactions ISO RGD:736485 6480464 corosolic acid inhibits the reaction [Doxorubicin results in increased expression of SQSTM1 protein] more ... CTD PMID:34296331 , PMID:35134463 doxorubicin decreases expression ISO RGD:736484 6480464 Doxorubicin results in decreased expression of SQSTM1 protein CTD PMID:29729358 more ... doxorubicin decreases expression EXP 6480464 Doxorubicin results in decreased expression of SQSTM1 protein CTD PMID:27666003 more ... doxorubicin increases expression ISO RGD:736485 6480464 Doxorubicin results in increased expression of SQSTM1 mRNA, Doxorubicin results in increased expression of SQSTM1 protein CTD PMID:16243910 more ... doxorubicin multiple interactions ISO RGD:736484 6480464 2-morpholin-4-yl-6-thianthren-1-yl-pyran-4-one inhibits the reaction [Doxorubicin results in increased degradation of SQSTM1 protein] more ... CTD PMID:22927544 more ... doxorubicin increases degradation ISO RGD:736484 6480464 Doxorubicin results in increased degradation of SQSTM1 protein CTD PMID:22927544 doxorubicin increases expression EXP 6480464 Doxorubicin results in increased expression of SQSTM1 mRNA, Doxorubicin results in increased expression of SQSTM1 protein CTD PMID:19915844 more ... elemental selenium multiple interactions EXP 6480464 Selenium inhibits the reaction [arsenite results in increased expression of SQSTM1 protein] CTD PMID:29324385 embelin increases degradation ISO RGD:736484 6480464 embelin results in increased degradation of SQSTM1 protein CTD PMID:28722333 endosulfan increases expression EXP 6480464 Endosulfan results in increased expression of SQSTM1 mRNA CTD PMID:29391264 Enterolactone multiple interactions ISO RGD:736484 6480464 [Coumestrol co-treated with 2, 3-bis(3'-hydroxybenzyl)butyrolactone] results in decreased expression of SQSTM1 mRNA CTD PMID:19167446 epichlorohydrin increases expression ISO RGD:736484 6480464 Epichlorohydrin results in increased expression of SQSTM1 mRNA CTD PMID:24211530 erlotinib hydrochloride increases expression ISO RGD:736484 6480464 Erlotinib Hydrochloride results in increased expression of SQSTM1 protein CTD PMID:30136359 ethanol multiple interactions ISO RGD:736485 6480464 [Wortmannin co-treated with Ethanol] results in increased expression of SQSTM1 protein more ... CTD PMID:22459179 more ... ethanol multiple interactions EXP 6480464 3-methyladenine inhibits the reaction [Ethanol promotes the reaction [Mirtazapine results in increased expression of SQSTM1 protein]] more ... CTD PMID:35066094 ethanol affects splicing ISO RGD:736485 6480464 Ethanol affects the splicing of SQSTM1 mRNA CTD PMID:30319688 ethanol decreases expression ISO RGD:736484 6480464 Ethanol results in decreased expression of SQSTM1 protein CTD PMID:29524503 , PMID:35595033 ethanol increases expression ISO RGD:736484 6480464 Ethanol results in increased expression of SQSTM1 protein CTD PMID:24582693 , PMID:34405320 ethanol multiple interactions ISO RGD:736484 6480464 ADIPOQ protein inhibits the reaction [Ethanol results in increased expression of SQSTM1 protein] more ... CTD PMID:24582693 , PMID:34405320 ethanol increases degradation ISO RGD:736485 6480464 Ethanol results in increased degradation of SQSTM1 protein CTD PMID:24492484 ethanol decreases expression ISO RGD:736485 6480464 Ethanol results in decreased expression of SQSTM1 protein CTD PMID:22459179 , PMID:24095927 ethanol decreases expression EXP 6480464 Ethanol results in decreased expression of SQSTM1 mRNA CTD PMID:16098508 ethanol increases expression ISO RGD:736485 6480464 Ethanol results in increased expression of SQSTM1 mRNA, Ethanol results in increased expression of SQSTM1 protein CTD PMID:25460735 more ... ethyl methanesulfonate increases expression ISO RGD:736484 6480464 Ethyl Methanesulfonate results in increased expression of SQSTM1 mRNA CTD PMID:23649840 eugenol increases expression ISO RGD:736484 6480464 Eugenol results in increased expression of SQSTM1 mRNA CTD PMID:26198647 excitatory amino acid agonist increases degradation EXP 6480464 Excitatory Amino Acid Agonists results in increased degradation of SQSTM1 protein CTD PMID:24675465 fenofibrate increases expression EXP 6480464 Fenofibrate results in increased expression of SQSTM1 mRNA CTD PMID:25596134 fenthion increases expression ISO RGD:736485 6480464 Fenthion results in increased expression of SQSTM1 mRNA CTD PMID:34813904 fenvalerate decreases expression EXP 6480464 fenvalerate results in decreased expression of SQSTM1 protein CTD PMID:31734597 fenvalerate multiple interactions EXP 6480464 3-methyladenine inhibits the reaction [fenvalerate results in decreased expression of SQSTM1 protein], SB 203580 inhibits the reaction [fenvalerate results in decreased expression of SQSTM1 protein] CTD PMID:31734597 ferrostatin-1 multiple interactions EXP 6480464 ferrostatin-1 inhibits the reaction [Arsenic Trioxide results in increased expression of SQSTM1 protein] CTD PMID:35195477 fingolimod hydrochloride multiple interactions ISO RGD:736484 6480464 Fingolimod Hydrochloride affects the reaction [bafilomycin A1 results in increased expression of SQSTM1 protein] more ... CTD PMID:25939952 fingolimod hydrochloride decreases expression ISO RGD:736484 6480464 Fingolimod Hydrochloride results in decreased expression of SQSTM1 protein CTD PMID:25939952 flavokawain B increases expression ISO RGD:736484 6480464 flavokawain B results in increased expression of SQSTM1 protein CTD PMID:30025493 flufenoxuron increases phosphorylation ISO RGD:736485 6480464 flufenoxuron results in increased phosphorylation of SQSTM1 protein CTD PMID:33771252 fluoxetine decreases expression ISO RGD:736485 6480464 Fluoxetine results in decreased expression of SQSTM1 mRNA CTD PMID:17105902 flutamide increases expression EXP 6480464 Flutamide results in increased expression of SQSTM1 mRNA CTD PMID:24136188 folic acid multiple interactions ISO RGD:736485 6480464 [1, 2-Dimethylhydrazine co-treated with Folic Acid] results in decreased expression of SQSTM1 mRNA CTD PMID:22206623 folic acid increases expression ISO RGD:736485 6480464 Folic Acid results in increased expression of SQSTM1 mRNA CTD PMID:25629700 formaldehyde increases expression ISO RGD:736484 6480464 Formaldehyde results in increased expression of SQSTM1 mRNA CTD PMID:20655997 , PMID:23649840 fructose multiple interactions EXP 6480464 [dapagliflozin co-treated with Atorvastatin] inhibits the reaction [[Dietary Fats co-treated with Fructose] results in increased expression of SQSTM1 protein], [Dietary Fats co-treated with Fructose] results in increased expression of SQSTM1 protein CTD PMID:34939712 fumonisin B1 increases expression ISO RGD:736485 6480464 fumonisin B1 results in increased expression of SQSTM1 mRNA CTD PMID:16221962 furosemide multiple interactions EXP 6480464 [Drinking Water deficiency co-treated with Furosemide] results in increased expression of SQSTM1 protein more ... CTD PMID:29860548 Fusaric acid decreases expression ISO RGD:736484 6480464 Fusaric Acid results in decreased expression of SQSTM1 protein CTD PMID:30582969 gadolinium atom multiple interactions ISO RGD:736484 6480464 [gadolinium chloride results in increased abundance of Gadolinium] which results in increased expression of SQSTM1 mRNA CTD PMID:34878122 gadolinium trichloride multiple interactions ISO RGD:736484 6480464 [gadolinium chloride results in increased abundance of Gadolinium] which results in increased expression of SQSTM1 mRNA CTD PMID:34878122 galactose multiple interactions ISO RGD:736484 6480464 Hydroxychloroquine inhibits the reaction [Metformin inhibits the reaction [Galactose results in increased expression of SQSTM1 protein]] more ... CTD PMID:28302704 , PMID:29426000 galactose increases expression ISO RGD:736484 6480464 Galactose results in increased expression of SQSTM1 protein CTD PMID:28302704 , PMID:29426000 galactose increases expression EXP 6480464 Galactose results in increased expression of SQSTM1 protein CTD PMID:28302704 gamma-hexachlorocyclohexane increases expression ISO RGD:736484 6480464 Hexachlorocyclohexane results in increased expression of SQSTM1 mRNA CTD PMID:26198647 gefitinib decreases expression ISO RGD:736484 6480464 Gefitinib results in decreased expression of SQSTM1 protein CTD PMID:25979647 , PMID:27639429 gefitinib multiple interactions ISO RGD:736484 6480464 [Gefitinib co-treated with Cisplatin] results in decreased expression of SQSTM1 protein, EGFR gene mutant form promotes the reaction [Gefitinib results in decreased expression of SQSTM1 protein] CTD PMID:25979647 , PMID:27639429 Genipin multiple interactions ISO RGD:736485 6480464 genipin inhibits the reaction [[Blood Glucose deficiency co-treated with Oxygen deficiency] results in increased expression of SQSTM1 protein] CTD PMID:28477916 genistein decreases expression ISO RGD:736484 6480464 Genistein results in decreased expression of SQSTM1 mRNA CTD PMID:16474171 gentamycin increases expression EXP 6480464 Gentamicins results in increased expression of SQSTM1 mRNA CTD PMID:33387578 geraniol increases expression ISO RGD:736484 6480464 geraniol results in increased expression of SQSTM1 mRNA CTD PMID:27683099 geraniol multiple interactions ISO RGD:736484 6480464 geraniol inhibits the reaction [Rotenone results in decreased expression of SQSTM1 protein] CTD PMID:30141137 ginsenoside Rg2 decreases expression ISO RGD:736485 6480464 ginsenoside Rg2 results in decreased expression of SQSTM1 protein CTD PMID:27305347 ginsenoside Rg2 decreases expression ISO RGD:736484 6480464 ginsenoside Rg2 results in decreased expression of SQSTM1 protein CTD PMID:27305347 ginsenoside Rg2 multiple interactions ISO RGD:736484 6480464 bafilomycin A1 promotes the reaction [ginsenoside Rg2 results in decreased expression of SQSTM1 protein] CTD PMID:27305347 glucose increases expression EXP 6480464 Glucose results in increased expression of SQSTM1 protein CTD PMID:28713934 more ... glucose increases expression ISO RGD:736484 6480464 Glucose deficiency results in increased expression of SQSTM1 protein CTD PMID:34580807 glucose increases expression ISO RGD:736485 6480464 Glucose results in increased expression of SQSTM1 protein CTD PMID:30459625 glucose multiple interactions ISO RGD:736485 6480464 HU 308 inhibits the reaction [Glucose results in increased expression of SQSTM1 protein] CTD PMID:30459625 glucose decreases expression ISO RGD:736484 6480464 Glucose deficiency results in decreased expression of SQSTM1 protein CTD PMID:29649567 glucose multiple interactions EXP 6480464 3-methyladenine inhibits the reaction [N-(1 more ... CTD PMID:28713934 more ... glutathione multiple interactions ISO RGD:736484 6480464 Glutathione inhibits the reaction [Doxorubicin results in increased degradation of SQSTM1 protein], Glutathione inhibits the reaction [Ivermectin results in decreased expression of SQSTM1 protein] CTD PMID:22927544 , PMID:34904774 glycerol 2-phosphate multiple interactions ISO RGD:736484 6480464 [Dexamethasone co-treated with ascorbate-2-phosphate co-treated with beta-glycerophosphoric acid] affects the expression of SQSTM1 protein CTD PMID:23111315 glycidol multiple interactions EXP 6480464 alpha-Chlorohydrin promotes the reaction [glycidol results in increased expression of SQSTM1 protein], glycidol promotes the reaction [alpha-Chlorohydrin results in increased expression of SQSTM1 protein] CTD PMID:33187795 glycidol increases expression EXP 6480464 glycidol results in increased expression of SQSTM1 protein CTD PMID:33187795 glycochenodeoxycholic acid multiple interactions ISO RGD:736484 6480464 [Atazanavir Sulfate co-treated with Glycochenodeoxycholic Acid co-treated with Deoxycholic Acid co-treated with Chenodeoxycholic Acid co-treated with Glycodeoxycholic Acid co-treated with Glycocholic Acid] results in increased expression of SQSTM1 mRNA more ... CTD PMID:32152650 glycocholic acid multiple interactions ISO RGD:736484 6480464 [Atazanavir Sulfate co-treated with Glycochenodeoxycholic Acid co-treated with Deoxycholic Acid co-treated with Chenodeoxycholic Acid co-treated with Glycodeoxycholic Acid co-treated with Glycocholic Acid] results in increased expression of SQSTM1 mRNA more ... CTD PMID:32152650 glycodeoxycholic acid multiple interactions ISO RGD:736484 6480464 [Atazanavir Sulfate co-treated with Glycochenodeoxycholic Acid co-treated with Deoxycholic Acid co-treated with Chenodeoxycholic Acid co-treated with Glycodeoxycholic Acid co-treated with Glycocholic Acid] results in increased expression of SQSTM1 mRNA more ... CTD PMID:32152650 glycyrrhizinic acid multiple interactions EXP 6480464 Glycyrrhizic Acid affects the reaction [Doxorubicin results in increased expression of SQSTM1 protein] CTD PMID:32525084 gossypetin multiple interactions ISO RGD:736484 6480464 gossypetin inhibits the reaction [malondialdehyde-low density lipoprotein, human results in increased expression of SQSTM1 protein] CTD PMID:25622137 graphene oxide multiple interactions ISO RGD:736485 6480464 dorsomorphin inhibits the reaction [graphene oxide results in decreased expression of SQSTM1 protein] CTD PMID:32430275 graphene oxide decreases expression ISO RGD:736485 6480464 graphene oxide results in decreased expression of SQSTM1 protein CTD PMID:32430275 graphene oxide multiple interactions ISO RGD:736484 6480464 dorsomorphin inhibits the reaction [graphene oxide results in decreased expression of SQSTM1 protein] CTD PMID:32430275 graphene oxide decreases expression ISO RGD:736484 6480464 graphene oxide results in decreased expression of SQSTM1 protein CTD PMID:32430275 graphite increases expression ISO RGD:736485 6480464 Graphite metabolite results in increased expression of SQSTM1 protein CTD PMID:27845169 graphite affects expression EXP 6480464 Graphite affects the expression of SQSTM1 mRNA CTD PMID:29933104 GW 4064 increases expression ISO RGD:736485 6480464 GW 4064 results in increased expression of SQSTM1 mRNA, GW 4064 results in increased expression of SQSTM1 protein CTD PMID:22952826 hexadecanoic acid increases expression ISO RGD:736485 6480464 Palmitic Acid results in increased expression of SQSTM1 protein CTD PMID:30208301 hexadecanoic acid increases expression EXP 6480464 Palmitic Acid results in increased expression of SQSTM1 protein CTD PMID:32278738 , PMID:34774660 hexadecanoic acid multiple interactions EXP 6480464 CYLD protein affects the reaction [Palmitic Acid results in increased expression of SQSTM1 protein] more ... CTD PMID:34774660 hexadecanoic acid multiple interactions ISO RGD:736484 6480464 Deferoxamine promotes the reaction [Palmitic Acid results in increased expression of SQSTM1 protein] more ... CTD PMID:30208301 more ... hexadecanoic acid multiple interactions ISO RGD:736485 6480464 trigonelline inhibits the reaction [Palmitic Acid results in increased expression of SQSTM1 protein] CTD PMID:30208301 hexadecanoic acid increases expression ISO RGD:736484 6480464 Palmitic Acid results in increased expression of SQSTM1 protein CTD PMID:30208301 , PMID:32283200 hexamethylene diisocyanate increases expression ISO RGD:736484 6480464 1, 6-hexamethylene diisocyanate results in increased expression of SQSTM1 mRNA CTD PMID:24211530 HU-308 multiple interactions ISO RGD:736485 6480464 [HU 308 co-treated with Dextran Sulfate] affects the expression of SQSTM1 protein more ... CTD PMID:27611972 , PMID:30459625 hydrogen peroxide decreases response to substance ISO RGD:736484 6480464 SQSTM1 protein results in decreased susceptibility to Hydrogen Peroxide CTD PMID:17360324 hydrogen peroxide decreases expression ISO RGD:736485 6480464 Hydrogen Peroxide results in decreased expression of SQSTM1 protein CTD PMID:34740634 hydrogen peroxide multiple interactions ISO RGD:736485 6480464 [Hydrogen Peroxide co-treated with N-(oxo-5 more ... CTD PMID:31494107 , PMID:34740634 hydrogen peroxide increases expression ISO RGD:736484 6480464 Hydrogen Peroxide results in increased expression of SQSTM1 mRNA, Hydrogen Peroxide results in increased expression of SQSTM1 protein CTD PMID:28285367 , PMID:34581912 hydrogen peroxide increases expression EXP 6480464 Hydrogen Peroxide results in increased expression of SQSTM1 protein CTD PMID:24889822 hydrogen peroxide multiple interactions EXP 6480464 bafilomycin A1 promotes the reaction [Hydrogen Peroxide results in increased expression of SQSTM1 protein] more ... CTD PMID:24889822 hydrogen peroxide affects expression ISO RGD:736484 6480464 Hydrogen Peroxide affects the expression of SQSTM1 mRNA CTD PMID:23410634 hydroquinone decreases expression ISO RGD:736484 6480464 hydroquinone results in decreased expression of SQSTM1 protein CTD PMID:28263894 hydroquinone multiple interactions ISO RGD:736484 6480464 4-(4-fluorophenyl)-2-(4-hydroxyphenyl)-5-(4-pyridyl)imidazole inhibits the reaction [[venetoclax co-treated with WEHI-539 co-treated with hydroquinone] results in decreased expression of SQSTM1 protein] more ... CTD PMID:35302183 , PMID:35561756 hydroxychloroquine multiple interactions ISO RGD:736484 6480464 Hydroxychloroquine inhibits the reaction [Metformin inhibits the reaction [Galactose results in increased expression of SQSTM1 protein]] CTD PMID:29426000 hydroxychloroquine multiple interactions ISO RGD:736485 6480464 [Dronabinol co-treated with Hydroxychloroquine] results in increased expression of SQSTM1 protein, [HU 211 co-treated with Hydroxychloroquine] results in increased expression of SQSTM1 protein CTD PMID:32773031 hydroxychloroquine increases expression ISO RGD:736485 6480464 Hydroxychloroquine results in increased expression of SQSTM1 protein CTD PMID:32773031 hydroxychloroquine increases expression ISO RGD:736484 6480464 Hydroxychloroquine results in increased expression of SQSTM1 protein CTD PMID:29426000 hypochlorous acid increases expression ISO RGD:736485 6480464 Hypochlorous Acid results in increased expression of SQSTM1 mRNA CTD PMID:19376150 ifosfamide increases expression ISO RGD:736484 6480464 Ifosfamide results in increased expression of SQSTM1 mRNA CTD PMID:25596134 indometacin multiple interactions ISO RGD:736484 6480464 [INS protein co-treated with Dexamethasone co-treated with 1-Methyl-3-isobutylxanthine co-treated with Indomethacin co-treated with bis(4-hydroxyphenyl)sulfone] results in increased expression of SQSTM1 mRNA, [INS protein co-treated with Dexamethasone co-treated with 1-Methyl-3-isobutylxanthine co-treated with Indomethacin co-treated with bisphenol A] results in decreased expression of SQSTM1 mRNA CTD PMID:28628672 inositol multiple interactions EXP 6480464 Inositol inhibits the reaction [Glucose results in increased expression of SQSTM1 protein] CTD PMID:35243728 iodixanol multiple interactions EXP 6480464 iodixanol inhibits the reaction [[Drinking Water deficiency co-treated with Furosemide] results in increased expression of SQSTM1 protein] CTD PMID:29860548 iohexol multiple interactions EXP 6480464 Iohexol inhibits the reaction [[Drinking Water deficiency co-treated with Furosemide] results in increased expression of SQSTM1 protein] CTD PMID:29860548 iron atom multiple interactions ISO RGD:736484 6480464 [Arsenic co-treated with Iron] results in increased expression of SQSTM1 mRNA more ... CTD PMID:25301941 , PMID:31739468 iron(0) multiple interactions ISO RGD:736484 6480464 [Arsenic co-treated with Iron] results in increased expression of SQSTM1 mRNA more ... CTD PMID:25301941 , PMID:31739468 iron(III) citrate increases expression ISO RGD:736484 6480464 ferric citrate results in increased expression of SQSTM1 mRNA CTD PMID:29959986 isoflavones affects expression ISO RGD:736484 6480464 Isoflavones affects the expression of SQSTM1 mRNA CTD PMID:16365062 isoflavones increases expression ISO RGD:736484 6480464 Isoflavones results in increased expression of SQSTM1 mRNA CTD PMID:17374662 isoprenaline increases expression ISO RGD:736485 6480464 Isoproterenol results in increased expression of SQSTM1 mRNA CTD PMID:20003209 ivermectin decreases expression ISO RGD:736484 6480464 Ivermectin results in decreased expression of SQSTM1 protein CTD PMID:32959892 , PMID:34904774 ivermectin multiple interactions ISO RGD:736484 6480464 3-methyladenine inhibits the reaction [Ivermectin results in decreased expression of SQSTM1 protein] more ... CTD PMID:34904774 kainic acid multiple interactions EXP 6480464 NADP inhibits the reaction [Kainic Acid results in decreased expression of SQSTM1 protein] CTD PMID:32057834 kainic acid decreases expression EXP 6480464 Kainic Acid results in decreased expression of SQSTM1 protein CTD PMID:32057834 ketamine increases expression ISO RGD:736485 6480464 Ketamine results in increased expression of SQSTM1 mRNA, Ketamine results in increased expression of SQSTM1 protein CTD PMID:34487425 L-ascorbic acid multiple interactions ISO RGD:736484 6480464 [[Ascorbic Acid co-treated with Chir 99021 co-treated with XAV939 co-treated with BMP4 protein co-treated with FGF1 protein co-treated with WNT3A protein co-treated with HGF protein] co-treated with [INHBA protein binds to INHBA protein]] results in increased expression of SQSTM1 mRNA, Ascorbic Acid inhibits the reaction [[Vehicle Emissions results in increased abundance of Particulate Matter] which results in increased expression of SQSTM1 mRNA] CTD PMID:32525552 , PMID:34480604 L-ascorbic acid 2-phosphate multiple interactions ISO RGD:736484 6480464 [[ascorbate-2-phosphate co-treated with Chir 99021 co-treated with XAV939 co-treated with BMP4 protein] co-treated with [INHBA protein binds to INHBA protein]] results in increased expression of SQSTM1 mRNA, [Dexamethasone co-treated with ascorbate-2-phosphate co-treated with beta-glycerophosphoric acid] affects the expression of SQSTM1 protein CTD PMID:23111315 , PMID:34480604 L-leucine multiple interactions ISO RGD:736485 6480464 Leucine inhibits the reaction [[Dextran Sulfate co-treated with alpinetin] results in decreased expression of SQSTM1 protein] CTD PMID:31676321 lactulose increases expression ISO RGD:736485 6480464 Lactulose results in increased expression of SQSTM1 mRNA CTD PMID:30335591 lactulose multiple interactions EXP 6480464 Lactulose promotes the reaction [Methamphetamine results in increased expression of SQSTM1 mRNA] CTD PMID:30450033 lead diacetate increases expression ISO RGD:736485 6480464 lead acetate results in increased expression of SQSTM1 mRNA CTD PMID:29746905 lead diacetate multiple interactions ISO RGD:736484 6480464 (1E more ... CTD PMID:34842334 lead diacetate increases expression ISO RGD:736484 6480464 lead acetate results in increased expression of SQSTM1 protein CTD PMID:34842334 lead diacetate decreases expression EXP 6480464 lead acetate results in decreased expression of SQSTM1 protein CTD PMID:32879255 lead nitrate multiple interactions ISO RGD:736485 6480464 lead nitrate affects the reaction [SQSTM1 affects the expression of MT1 mRNA], lead nitrate affects the reaction [SQSTM1 affects the expression of MT2 mRNA] CTD PMID:11891201 lead nitrate increases expression EXP 6480464 lead nitrate results in increased expression of SQSTM1 protein CTD PMID:27762461 lead nitrate multiple interactions EXP 6480464 puerarin inhibits the reaction [lead nitrate results in increased expression of SQSTM1 protein] CTD PMID:27762461 lead(0) affects splicing ISO RGD:736484 6480464 Lead affects the splicing of SQSTM1 mRNA CTD PMID:28903495 lead(0) decreases expression EXP 6480464 Lead results in decreased expression of SQSTM1 protein CTD PMID:29630945 lead(0) multiple interactions EXP 6480464 Grape Seed Proanthocyanidins inhibits the reaction [Lead results in decreased expression of SQSTM1 protein], NFE2L2 protein affects the reaction [Grape Seed Proanthocyanidins inhibits the reaction [Lead results in decreased expression of SQSTM1 protein]] CTD PMID:29630945 lead(0) affects expression ISO RGD:736484 6480464 Lead affects the expression of SQSTM1 mRNA CTD PMID:28903495 lead(2+) affects splicing ISO RGD:736484 6480464 Lead affects the splicing of SQSTM1 mRNA CTD PMID:28903495 lead(2+) multiple interactions EXP 6480464 Grape Seed Proanthocyanidins inhibits the reaction [Lead results in decreased expression of SQSTM1 protein], NFE2L2 protein affects the reaction [Grape Seed Proanthocyanidins inhibits the reaction [Lead results in decreased expression of SQSTM1 protein]] CTD PMID:29630945 lead(2+) decreases expression EXP 6480464 Lead results in decreased expression of SQSTM1 protein CTD PMID:29630945 lead(2+) affects expression ISO RGD:736484 6480464 Lead affects the expression of SQSTM1 mRNA CTD PMID:28903495 leflunomide increases expression EXP 6480464 leflunomide results in increased expression of SQSTM1 mRNA CTD PMID:24136188 leflunomide increases expression ISO RGD:736484 6480464 leflunomide results in increased expression of SQSTM1 mRNA CTD PMID:28988120 lipopolysaccharide multiple interactions ISO RGD:736485 6480464 3-methyladenine inhibits the reaction [anemoside B4 inhibits the reaction [Lipopolysaccharides results in increased expression of SQSTM1 protein]] more ... CTD PMID:27611972 more ... lipopolysaccharide multiple interactions ISO RGD:736484 6480464 [NAT10 protein affects the susceptibility to Lipopolysaccharides] which affects the expression of SQSTM1 mRNA more ... CTD PMID:35811015 , PMID:35877022 lipopolysaccharide increases expression EXP 6480464 Lipopolysaccharides results in increased expression of SQSTM1 mRNA, Lipopolysaccharides results in increased expression of SQSTM1 protein CTD PMID:34464015 lipopolysaccharide increases expression ISO RGD:736485 6480464 Lipopolysaccharides results in increased expression of SQSTM1 mRNA, Lipopolysaccharides results in increased expression of SQSTM1 protein CTD PMID:34051206 , PMID:35099110 liquiritigenin multiple interactions EXP 6480464 liquiritigenin inhibits the reaction [Monocrotaline results in increased expression of SQSTM1 protein] CTD PMID:29908794 liquiritin multiple interactions EXP 6480464 liquiritin inhibits the reaction [Monocrotaline results in increased expression of SQSTM1 protein] CTD PMID:29908794 lithium chloride multiple interactions ISO RGD:736485 6480464 Lithium Chloride promotes the reaction [Cisplatin results in decreased expression of SQSTM1 protein] CTD PMID:31220555 LY294002 multiple interactions ISO RGD:736484 6480464 2-(4-morpholinyl)-8-phenyl-4H-1-benzopyran-4-one inhibits the reaction [pachastrissamine analog results in increased expression of SQSTM1 protein], 2-(4-morpholinyl)-8-phenyl-4H-1-benzopyran-4-one inhibits the reaction [SQSTM1 protein results in increased expression of NQO1 protein] CTD PMID:17360324 , PMID:35123989 LY294002 multiple interactions ISO RGD:736485 6480464 2-(4-morpholinyl)-8-phenyl-4H-1-benzopyran-4-one inhibits the reaction [notoginsenoside R1 affects the localization of SQSTM1 protein], 2-(4-morpholinyl)-8-phenyl-4H-1-benzopyran-4-one inhibits the reaction [notoginsenoside R1 inhibits the reaction [triethylene glycol dimethacrylate affects the localization of SQSTM1 protein]] CTD PMID:33689844 lycopene multiple interactions ISO RGD:736485 6480464 Lycopene inhibits the reaction [Atrazine results in increased expression of SQSTM1 mRNA alternative form] more ... CTD PMID:30360616 manganese(II) chloride multiple interactions EXP 6480464 Acetylcysteine promotes the reaction [manganese chloride results in increased expression of SQSTM1 protein] more ... CTD PMID:29222055 manganese(II) chloride affects expression ISO RGD:736484 6480464 manganese chloride affects the expression of SQSTM1 protein CTD PMID:30578841 manganese(II) chloride increases expression ISO RGD:736484 6480464 manganese chloride results in increased expression of SQSTM1 protein CTD PMID:30672645 manganese(II) chloride multiple interactions ISO RGD:736484 6480464 [N-((3-(aminomethyl)phenyl)methyl)ethanimidamide co-treated with manganese chloride] results in decreased expression of SQSTM1 protein, corynoxine B affects the reaction [manganese chloride affects the expression of SQSTM1 protein] CTD PMID:28856835 , PMID:30578841 manganese(II) chloride increases expression EXP 6480464 manganese chloride results in increased expression of SQSTM1 protein CTD PMID:29222055 melatonin multiple interactions EXP 6480464 Melatonin inhibits the reaction [Carbon Tetrachloride results in increased expression of SQSTM1 protein] CTD PMID:26882442 melatonin multiple interactions ISO RGD:736484 6480464 Melatonin inhibits the reaction [cyfluthrin results in increased expression of SQSTM1 mRNA] CTD PMID:31330490 melatonin multiple interactions ISO RGD:736485 6480464 Melatonin inhibits the reaction [Radon results in increased expression of SQSTM1 protein] CTD PMID:33107683 melibiose increases expression ISO RGD:736485 6480464 Melibiose results in increased expression of SQSTM1 mRNA CTD PMID:30335591 menadione increases expression ISO RGD:736485 6480464 Vitamin K 3 results in increased expression of SQSTM1 mRNA CTD PMID:25270620 menadione increases expression ISO RGD:736484 6480464 Vitamin K 3 results in increased expression of SQSTM1 mRNA CTD PMID:23410634 mercury dibromide increases expression ISO RGD:736484 6480464 mercuric bromide results in increased expression of SQSTM1 mRNA CTD PMID:26272509 mercury dibromide multiple interactions ISO RGD:736484 6480464 [NOG protein co-treated with mercuric bromide co-treated with dorsomorphin co-treated with 4-(5-benzo(1, 3)dioxol-5-yl-4-pyridin-2-yl-1H-imidazol-2-yl)benzamide] results in increased expression of SQSTM1 mRNA CTD PMID:27188386 mesalamine multiple interactions EXP 6480464 Mesalamine inhibits the reaction [Trinitrobenzenesulfonic Acid results in increased expression of SQSTM1 protein] CTD PMID:33412153 metformin increases expression EXP 6480464 Metformin results in increased expression of SQSTM1 mRNA CTD PMID:25596134 metformin decreases expression ISO RGD:736484 6480464 Metformin results in decreased expression of SQSTM1 protein CTD PMID:35350904 metformin multiple interactions ISO RGD:736484 6480464 [Simvastatin co-treated with Metformin] results in decreased expression of SQSTM1 protein more ... CTD PMID:25412314 more ... methamphetamine increases expression ISO RGD:736485 6480464 Methamphetamine results in increased expression of SQSTM1 protein CTD PMID:23933405 , PMID:34562559 methamphetamine multiple interactions ISO RGD:736485 6480464 SNCA protein affects the reaction [Methamphetamine results in increased expression of SQSTM1 protein], TFEB protein inhibits the reaction [Methamphetamine results in increased expression of SQSTM1 protein] CTD PMID:34562559 methamphetamine multiple interactions EXP 6480464 Lactulose promotes the reaction [Methamphetamine results in increased expression of SQSTM1 mRNA], STX17 protein inhibits the reaction [Methamphetamine results in increased expression of SQSTM1 protein] CTD PMID:30450033 , PMID:34374793 methamphetamine increases expression EXP 6480464 Methamphetamine results in increased expression of SQSTM1 mRNA, Methamphetamine results in increased expression of SQSTM1 protein CTD PMID:30450033 , PMID:34374793 methidathion increases expression ISO RGD:736485 6480464 methidathion results in increased expression of SQSTM1 mRNA CTD PMID:34813904 methotrexate increases expression ISO RGD:736484 6480464 Methotrexate results in increased expression of SQSTM1 mRNA CTD PMID:21678067 methoxyacetic acid increases expression EXP 6480464 methoxyacetic acid results in increased expression of SQSTM1 mRNA CTD PMID:20864626 , PMID:9681501 methyl methanesulfonate decreases expression ISO RGD:736484 6480464 Methyl Methanesulfonate results in decreased expression of SQSTM1 mRNA CTD PMID:23649840 methyl methanesulfonate increases expression ISO RGD:736484 6480464 Methyl Methanesulfonate results in increased expression of SQSTM1 mRNA CTD PMID:23649840 methylisothiazolinone increases expression ISO RGD:736484 6480464 2-methyl-4-isothiazolin-3-one results in increased expression of SQSTM1 protein CTD PMID:29110394 methylmercury chloride increases expression EXP 6480464 methylmercuric chloride results in increased expression of SQSTM1 mRNA CTD PMID:20864626 methylmercury chloride multiple interactions ISO RGD:736485 6480464 [Docosahexaenoic Acids co-treated with methylmercuric chloride] results in increased expression of SQSTM1 mRNA more ... CTD PMID:27667695 , PMID:30769081 methylmercury chloride increases expression ISO RGD:736485 6480464 methylmercuric chloride results in increased expression of SQSTM1 protein CTD PMID:27667695 methylmercury chloride increases expression ISO RGD:736484 6480464 methylmercuric chloride results in increased expression of SQSTM1 mRNA, methylmercuric chloride results in increased expression of SQSTM1 protein CTD PMID:27667695 more ... methylmercury(1+) increases expression EXP 6480464 methylmercury II results in increased expression of SQSTM1 mRNA CTD PMID:17905399 metronidazole multiple interactions ISO RGD:736485 6480464 [Vancomycin co-treated with Neomycin co-treated with Metronidazole] promotes the reaction [Zinc Oxide analog results in increased expression of SQSTM1 protein] CTD PMID:36535435 miconazole multiple interactions ISO RGD:736484 6480464 bafilomycin A1 promotes the reaction [Miconazole results in increased expression of SQSTM1 protein] CTD PMID:32981224 miconazole increases expression ISO RGD:736484 6480464 Miconazole results in increased expression of SQSTM1 protein CTD PMID:32981224 microcystin-LR multiple interactions ISO RGD:736485 6480464 4-methylumbelliferone 8-carbaldehyde inhibits the reaction [cyanoginosin LR results in decreased expression of SQSTM1 protein] more ... CTD PMID:33290805 microcystin-LR decreases expression ISO RGD:736485 6480464 cyanoginosin LR results in decreased expression of SQSTM1 protein CTD PMID:33290805 mifepristone multiple interactions ISO RGD:736484 6480464 Mifepristone inhibits the reaction [Dexamethasone results in decreased expression of SQSTM1 protein] CTD PMID:33359579 mirtazapine increases expression EXP 6480464 Mirtazapine results in increased expression of SQSTM1 protein CTD PMID:35066094 mirtazapine multiple interactions ISO RGD:736485 6480464 Ethanol promotes the reaction [Mirtazapine results in increased expression of SQSTM1 protein] CTD PMID:35066094 mirtazapine increases expression ISO RGD:736485 6480464 Mirtazapine results in increased expression of SQSTM1 protein CTD PMID:35066094 mirtazapine multiple interactions EXP 6480464 3-methyladenine inhibits the reaction [Ethanol promotes the reaction [Mirtazapine results in increased expression of SQSTM1 protein]] more ... CTD PMID:35066094 Monobutylphthalate increases expression EXP 6480464 monobutyl phthalate results in increased expression of SQSTM1 mRNA CTD PMID:20864626 monocrotaline increases expression EXP 6480464 Monocrotaline results in increased expression of SQSTM1 protein CTD PMID:29908794 monocrotaline multiple interactions EXP 6480464 liquiritigenin inhibits the reaction [Monocrotaline results in increased expression of SQSTM1 protein], liquiritin inhibits the reaction [Monocrotaline results in increased expression of SQSTM1 protein] CTD PMID:29908794 morusin increases expression ISO RGD:736484 6480464 morusin results in increased expression of SQSTM1 protein CTD PMID:29421517 morusin decreases expression ISO RGD:736484 6480464 morusin results in decreased expression of SQSTM1 protein CTD PMID:33035517 morusin multiple interactions ISO RGD:736484 6480464 4 more ... CTD PMID:29421517 , PMID:33035517 N,N-diethyl-m-toluamide multiple interactions EXP 6480464 [Pyridostigmine Bromide co-treated with DEET co-treated with Permethrin] results in increased expression of SQSTM1 mRNA CTD PMID:28659758 N-(1,3-benzodioxol-5-ylmethyl)-2,6-dichlorobenzamide multiple interactions EXP 6480464 3-methyladenine inhibits the reaction [N-(1 more ... CTD PMID:29128638 N-acetyl-L-cysteine multiple interactions ISO RGD:736484 6480464 Acetylcysteine inhibits the reaction [4-hydroxy-2-nonenal results in increased expression of SQSTM1 mRNA] more ... CTD PMID:22927544 more ... N-acetyl-L-cysteine increases expression ISO RGD:736485 6480464 Acetylcysteine results in increased expression of SQSTM1 protein CTD PMID:33462182 N-acetyl-L-cysteine multiple interactions ISO RGD:736485 6480464 Acetylcysteine inhibits the reaction [[Aluminum Chloride results in increased abundance of Aluminum] which results in decreased expression of SQSTM1 mRNA] more ... CTD PMID:32512069 more ... N-acetyl-L-cysteine multiple interactions EXP 6480464 Acetylcysteine inhibits the reaction [decamethrin results in increased expression of SQSTM1 protein], Acetylcysteine promotes the reaction [manganese chloride results in increased expression of SQSTM1 protein] CTD PMID:26588882 , PMID:29222055 N-benzyloxycarbonyl-L-leucyl-L-leucyl-L-leucinal multiple interactions ISO RGD:736484 6480464 benzyloxycarbonylleucyl-leucyl-leucine aldehyde promotes the reaction [ATG13 protein results in decreased expression of SQSTM1 protein], benzyloxycarbonylleucyl-leucyl-leucine aldehyde promotes the reaction [ATG7 protein results in decreased expression of SQSTM1 protein] CTD PMID:27629431 N-methyl-4-phenylpyridinium multiple interactions ISO RGD:736484 6480464 1-Methyl-4-phenylpyridinium promotes the reaction [SQSTM1 protein binds to and results in decreased activity of SQSTM1 protein] CTD PMID:26409479 N-methyl-4-phenylpyridinium increases expression ISO RGD:736485 6480464 1-Methyl-4-phenylpyridinium results in increased expression of SQSTM1 protein CTD PMID:30165626 N-methyl-4-phenylpyridinium increases expression EXP 6480464 1-Methyl-4-phenylpyridinium results in increased expression of SQSTM1 mRNA, 1-Methyl-4-phenylpyridinium results in increased expression of SQSTM1 protein CTD PMID:28801915 , PMID:30165626 N-methyl-4-phenylpyridinium multiple interactions ISO RGD:736485 6480464 Chir 99021 inhibits the reaction [1-Methyl-4-phenylpyridinium results in increased expression of SQSTM1 protein], Imatinib Mesylate inhibits the reaction [1-Methyl-4-phenylpyridinium results in increased expression of SQSTM1 protein] CTD PMID:30165626 N-methyl-4-phenylpyridinium multiple interactions EXP 6480464 Imatinib Mesylate inhibits the reaction [1-Methyl-4-phenylpyridinium results in increased expression of SQSTM1 protein] CTD PMID:30165626 N-methylformamide affects expression ISO RGD:736485 6480464 methylformamide affects the expression of SQSTM1 mRNA, methylformamide analog affects the expression of SQSTM1 mRNA CTD PMID:17040096 N-methylnicotinate multiple interactions ISO RGD:736485 6480464 trigonelline inhibits the reaction [[Cholesterol more ... CTD PMID:30208301 N-methylnicotinate multiple interactions ISO RGD:736484 6480464 trigonelline inhibits the reaction [Palmitic Acid results in increased expression of SQSTM1 protein] CTD PMID:30208301 N-nitrosodiethylamine increases expression ISO RGD:736485 6480464 Diethylnitrosamine results in increased expression of SQSTM1 mRNA CTD PMID:12771043 NADP zwitterion multiple interactions EXP 6480464 NADP inhibits the reaction [Kainic Acid results in decreased expression of SQSTM1 protein] CTD PMID:32057834 NADP(+) multiple interactions EXP 6480464 NADP inhibits the reaction [Kainic Acid results in decreased expression of SQSTM1 protein] CTD PMID:32057834 nefazodone increases expression EXP 6480464 nefazodone results in increased expression of SQSTM1 mRNA CTD PMID:24136188 nefazodone multiple interactions ISO RGD:736484 6480464 [nefazodone co-treated with Glycochenodeoxycholic Acid co-treated with Deoxycholic Acid co-treated with Chenodeoxycholic Acid co-treated with Glycodeoxycholic Acid co-treated with Glycocholic Acid] results in increased expression of SQSTM1 mRNA CTD PMID:32152650 nefazodone increases expression ISO RGD:736484 6480464 nefazodone results in increased expression of SQSTM1 mRNA CTD PMID:32152650 neomycin multiple interactions ISO RGD:736485 6480464 [Vancomycin co-treated with Neomycin co-treated with Metronidazole] promotes the reaction [Zinc Oxide analog results in increased expression of SQSTM1 protein] CTD PMID:36535435 nickel dichloride increases expression EXP 6480464 nickel chloride results in increased expression of SQSTM1 mRNA CTD PMID:22110744 nickel dichloride affects expression EXP 6480464 nickel chloride affects the expression of SQSTM1 mRNA CTD PMID:22546817 nicotinamide multiple interactions ISO RGD:736485 6480464 Niacinamide inhibits the reaction [Sirolimus results in decreased expression of SQSTM1 protein] CTD PMID:24238063 nicotine increases expression ISO RGD:736484 6480464 Nicotine results in increased expression of SQSTM1 protein CTD PMID:33010382 nicotine multiple interactions ISO RGD:736484 6480464 dorsomorphin inhibits the reaction [Nicotine promotes the reaction [Dextran Sulfate results in decreased expression of SQSTM1 protein]], Nicotine promotes the reaction [Dextran Sulfate results in decreased expression of SQSTM1 protein] CTD PMID:31926917 nicotine multiple interactions ISO RGD:736485 6480464 Nicotine promotes the reaction [Dextran Sulfate results in decreased expression of SQSTM1 protein] CTD PMID:31926917 nimesulide increases expression EXP 6480464 nimesulide results in increased expression of SQSTM1 mRNA CTD PMID:24136188 NMN zwitterion multiple interactions ISO RGD:736484 6480464 6-chloro-2 more ... CTD PMID:36336710 Nonidet P-40 decreases expression ISO RGD:736484 6480464 Nonidet P-40 results in decreased expression of SQSTM1 mRNA CTD PMID:26552463 notoginsenoside R1 affects localization ISO RGD:736485 6480464 notoginsenoside R1 affects the localization of SQSTM1 protein CTD PMID:33689844 notoginsenoside R1 multiple interactions ISO RGD:736485 6480464 2-(4-morpholinyl)-8-phenyl-4H-1-benzopyran-4-one inhibits the reaction [notoginsenoside R1 affects the localization of SQSTM1 protein] more ... CTD PMID:33689844 obeticholic acid multiple interactions ISO RGD:736485 6480464 obeticholic acid inhibits the reaction [Dietary Fats results in decreased expression of SQSTM1 protein] CTD PMID:26655953 ochratoxin A decreases expression ISO RGD:736484 6480464 ochratoxin A results in decreased expression of SQSTM1 mRNA CTD PMID:30559759 octreotide multiple interactions ISO RGD:736485 6480464 Octreotide inhibits the reaction [[[Oxygen deficiency co-treated with Blood Glucose deficiency] co-treated with [Oxygen co-treated with Blood Glucose]] results in decreased expression of SQSTM1 protein], SNHG12 mRNA promotes the reaction [Octreotide inhibits the reaction [[[Oxygen deficiency co-treated with Blood Glucose deficiency] co-treated with [Oxygen co-treated with Blood Glucose]] results in decreased expression of SQSTM1 mRNA]] CTD PMID:35307376 oleanolic acid increases expression ISO RGD:736484 6480464 Oleanolic Acid results in increased expression of SQSTM1 protein CTD PMID:35690101 oleic acid multiple interactions ISO RGD:736484 6480464 necrostatin-1 inhibits the reaction [Oleic Acid results in increased expression of SQSTM1 protein], PGAM5 protein promotes the reaction [Oleic Acid results in increased expression of SQSTM1 protein] CTD PMID:36273635 oleic acid increases expression ISO RGD:736484 6480464 Oleic Acid results in increased expression of SQSTM1 protein CTD PMID:36273635 oligomycin A multiple interactions ISO RGD:736484 6480464 [oligomycin A co-treated with Antimycin A] results in increased expression of SQSTM1 mRNA, PINK1 protein affects the reaction [[oligomycin A co-treated with Antimycin A] results in increased expression of SQSTM1 mRNA] CTD PMID:28366621 organoselenium compound multiple interactions ISO RGD:736484 6480464 [Organoselenium Compounds binds to Copper] which results in increased expression of SQSTM1 mRNA CTD PMID:25167922 osimertinib decreases expression ISO RGD:736484 6480464 osimertinib results in decreased expression of SQSTM1 protein CTD PMID:30145802 oxaliplatin multiple interactions EXP 6480464 [oxaliplatin co-treated with Topotecan] results in increased expression of SQSTM1 mRNA CTD PMID:25729387 oxidopamine multiple interactions ISO RGD:736484 6480464 Oxidopamine promotes the reaction [SQSTM1 protein binds to and results in decreased activity of SQSTM1 protein] CTD PMID:26409479 oxidopamine decreases expression EXP 6480464 Oxidopamine results in decreased expression of SQSTM1 protein CTD PMID:28802652 ozone multiple interactions ISO RGD:736484 6480464 [Acrolein co-treated with methacrylaldehyde co-treated with alpha-pinene co-treated with Ozone] results in increased expression of SQSTM1 mRNA more ... CTD PMID:32699268 ozone increases expression ISO RGD:736485 6480464 Ozone results in increased expression of SQSTM1 protein CTD PMID:35866636 p-chloromercuribenzoic acid increases expression ISO RGD:736484 6480464 p-Chloromercuribenzoic Acid results in increased expression of SQSTM1 mRNA CTD PMID:26272509 p-chloromercuribenzoic acid multiple interactions ISO RGD:736484 6480464 [NOG protein co-treated with p-Chloromercuribenzoic Acid co-treated with dorsomorphin co-treated with 4-(5-benzo(1, 3)dioxol-5-yl-4-pyridin-2-yl-1H-imidazol-2-yl)benzamide] results in increased expression of SQSTM1 mRNA CTD PMID:27188386 p-cresol multiple interactions ISO RGD:736484 6480464 SQSTM1 mutant form inhibits the reaction [4-cresol results in increased cleavage of CASP8 protein] CTD PMID:25668154 p-cresol increases expression ISO RGD:736484 6480464 4-cresol results in increased expression of SQSTM1 protein CTD PMID:25668154 Paeonol multiple interactions EXP 6480464 paeonol inhibits the reaction [Epirubicin results in increased expression of SQSTM1 protein] CTD PMID:29505745 paracetamol increases expression ISO RGD:736485 6480464 Acetaminophen results in increased expression of SQSTM1 mRNA CTD PMID:11264010 , PMID:12540782 paracetamol increases expression EXP 6480464 Acetaminophen results in increased expression of SQSTM1 mRNA CTD PMID:33387578 paracetamol decreases expression ISO RGD:736484 6480464 Acetaminophen results in decreased expression of SQSTM1 protein CTD PMID:29136249 paracetamol multiple interactions ISO RGD:736484 6480464 Chlorogenic Acid inhibits the reaction [Acetaminophen results in decreased expression of SQSTM1 protein] CTD PMID:29136249 paracetamol decreases expression ISO RGD:736485 6480464 Acetaminophen results in decreased expression of SQSTM1 protein CTD PMID:33271250 paracetamol increases expression ISO RGD:736484 6480464 Acetaminophen results in increased expression of SQSTM1 mRNA CTD PMID:21420995 , PMID:29067470 paracetamol affects expression ISO RGD:736485 6480464 Acetaminophen affects the expression of SQSTM1 mRNA CTD PMID:15606129 , PMID:17562736 paracetamol multiple interactions ISO RGD:736485 6480464 [Clofibrate co-treated with Acetaminophen] affects the expression of SQSTM1 mRNA more ... CTD PMID:12540782 more ... paraquat decreases expression ISO RGD:736485 6480464 Paraquat results in decreased expression of SQSTM1 protein CTD PMID:25092649 paraquat increases expression ISO RGD:736484 6480464 Paraquat results in increased expression of SQSTM1 mRNA, Paraquat results in increased expression of SQSTM1 protein CTD PMID:32306690 , PMID:35182771 paraquat increases expression EXP 6480464 Paraquat results in increased expression of SQSTM1 mRNA CTD PMID:32680482 paraquat decreases expression ISO RGD:736484 6480464 Paraquat results in decreased expression of SQSTM1 protein CTD PMID:30144575 paraquat multiple interactions ISO RGD:736485 6480464 bafilomycin A promotes the reaction [Paraquat results in increased expression of SQSTM1 protein], TLR4 protein affects the reaction [Paraquat results in increased expression of SQSTM1 protein] CTD PMID:27246695 paraquat increases expression ISO RGD:736485 6480464 Paraquat results in increased expression of SQSTM1 mRNA, Paraquat results in increased expression of SQSTM1 protein CTD PMID:12595580 , PMID:27246695 paraquat multiple interactions ISO RGD:736484 6480464 [Paraquat co-treated with MAP3K5 protein] results in increased degradation of SQSTM1 protein more ... CTD PMID:20929985 more ... paraquat increases degradation ISO RGD:736484 6480464 Paraquat results in increased degradation of SQSTM1 protein CTD PMID:20929985 patulin decreases expression ISO RGD:736484 6480464 Patulin results in decreased expression of SQSTM1 protein CTD PMID:29604266 patulin multiple interactions ISO RGD:736484 6480464 Acetylcysteine inhibits the reaction [Patulin results in decreased expression of SQSTM1 protein] CTD PMID:29604266 PCB138 decreases expression EXP 6480464 2 more ... CTD PMID:23829299 pentachlorophenol increases expression ISO RGD:736485 6480464 Pentachlorophenol results in increased expression of SQSTM1 mRNA CTD PMID:30597782 pepstatin A multiple interactions ISO RGD:736484 6480464 [aloxistatin co-treated with pepstatin] results in increased expression of SQSTM1 protein, [CA 074 methyl ester co-treated with pepstatin] results in increased expression of SQSTM1 protein CTD PMID:32186374 pepstatin A multiple interactions ISO RGD:736485 6480464 [aloxistatin co-treated with pepstatin] results in increased expression of SQSTM1 protein more ... CTD PMID:26483381 , PMID:32773031 perfluorooctane-1-sulfonic acid decreases expression EXP 6480464 perfluorooctane sulfonic acid results in decreased expression of SQSTM1 mRNA CTD PMID:18692542 perfluorooctane-1-sulfonic acid multiple interactions ISO RGD:736485 6480464 [perfluorooctane sulfonic acid co-treated with Cellulose] results in increased expression of SQSTM1 mRNA, PP242 inhibits the reaction [perfluorooctane sulfonic acid results in decreased degradation of SQSTM1 protein] CTD PMID:32861759 , PMID:36331819 perfluorooctane-1-sulfonic acid decreases degradation ISO RGD:736485 6480464 perfluorooctane sulfonic acid results in decreased degradation of SQSTM1 protein CTD PMID:32861759 perfluorooctanoic acid increases expression ISO RGD:736484 6480464 perfluorooctanoic acid results in increased expression of SQSTM1 protein CTD PMID:26879310 perfluorooctanoic acid increases expression ISO RGD:736485 6480464 perfluorooctanoic acid results in increased expression of SQSTM1 mRNA, perfluorooctanoic acid results in increased expression of SQSTM1 protein CTD PMID:26879310 , PMID:35066053 perfluoroundecanoic acid decreases expression EXP 6480464 perfluoroundecanoic acid results in decreased expression of SQSTM1 protein CTD PMID:33549592 permethrin multiple interactions EXP 6480464 [Pyridostigmine Bromide co-treated with DEET co-treated with Permethrin] results in increased expression of SQSTM1 mRNA CTD PMID:28659758 phenobarbital multiple interactions ISO RGD:736485 6480464 NR1I3 protein affects the reaction [Phenobarbital results in increased expression of SQSTM1 mRNA] CTD PMID:19482888 phenobarbital affects expression ISO RGD:736485 6480464 Phenobarbital affects the expression of SQSTM1 mRNA CTD PMID:23091169 phenobarbital increases expression ISO RGD:736485 6480464 Phenobarbital results in increased expression of SQSTM1 mRNA CTD PMID:19482888 phenol increases expression ISO RGD:736484 6480464 Phenol results in increased expression of SQSTM1 mRNA CTD PMID:26198647 phenylephrine decreases expression EXP 6480464 Phenylephrine results in decreased expression of SQSTM1 mRNA CTD PMID:18158353 phenylmercury acetate increases expression ISO RGD:736484 6480464 Phenylmercuric Acetate results in increased expression of SQSTM1 mRNA CTD PMID:26272509 phenylmercury acetate multiple interactions ISO RGD:736484 6480464 [NOG protein co-treated with Phenylmercuric Acetate co-treated with dorsomorphin co-treated with 4-(5-benzo(1, 3)dioxol-5-yl-4-pyridin-2-yl-1H-imidazol-2-yl)benzamide] results in increased expression of SQSTM1 mRNA CTD PMID:27188386 PhIP increases expression EXP 6480464 2-amino-1-methyl-6-phenylimidazo(4, 5-b)pyridine results in increased expression of SQSTM1 mRNA CTD PMID:15215175 phorbol 13-acetate 12-myristate increases expression ISO RGD:736484 6480464 Tetradecanoylphorbol Acetate results in increased expression of SQSTM1 mRNA CTD PMID:26198647 pirinixic acid multiple interactions ISO RGD:736484 6480464 [pirinixic acid binds to and results in increased activity of PPARA protein] which results in increased expression of SQSTM1 mRNA CTD PMID:19710929 piroxicam multiple interactions ISO RGD:736484 6480464 Cisplatin inhibits the reaction [Piroxicam results in decreased expression of SQSTM1 mRNA] CTD PMID:21858171 piroxicam decreases expression ISO RGD:736484 6480464 Piroxicam results in decreased expression of SQSTM1 mRNA CTD PMID:21858171 Plantamajoside multiple interactions ISO RGD:736484 6480464 plantamajoside promotes the reaction [Metformin results in decreased expression of SQSTM1 protein] CTD PMID:35350904 plumbagin increases expression ISO RGD:736484 6480464 plumbagin results in increased expression of SQSTM1 protein CTD PMID:31276663 potassium bromate increases expression ISO RGD:736484 6480464 potassium bromate results in increased expression of SQSTM1 mRNA CTD PMID:30559759 potassium chromate increases expression ISO RGD:736484 6480464 potassium chromate(VI) results in increased expression of SQSTM1 mRNA CTD PMID:22079256 potassium chromate multiple interactions ISO RGD:736484 6480464 [potassium chromate(VI) co-treated with epigallocatechin gallate] results in increased expression of SQSTM1 mRNA CTD PMID:22079256 potassium dichromate multiple interactions ISO RGD:736484 6480464 3-methyladenine inhibits the reaction [Potassium Dichromate results in decreased expression of SQSTM1 protein], 4-phenylbutyric acid inhibits the reaction [Potassium Dichromate results in decreased expression of SQSTM1 protein] CTD PMID:32569804 potassium dichromate decreases expression ISO RGD:736484 6480464 Potassium Dichromate results in decreased expression of SQSTM1 protein CTD PMID:32569804 potassium iodide multiple interactions ISO RGD:736484 6480464 3-methyladenine inhibits the reaction [Potassium Iodide results in increased expression of SQSTM1 mRNA] more ... CTD PMID:29923297 potassium iodide increases expression ISO RGD:736484 6480464 Potassium Iodide results in increased expression of SQSTM1 mRNA, Potassium Iodide results in increased expression of SQSTM1 protein CTD PMID:29923297 pregnenolone 16alpha-carbonitrile increases expression EXP 6480464 Pregnenolone Carbonitrile results in increased expression of SQSTM1 mRNA CTD PMID:19162173 prodigiosin increases expression ISO RGD:736484 6480464 Prodigiosin results in increased expression of SQSTM1 protein CTD PMID:31077745 prodigiosin multiple interactions ISO RGD:736484 6480464 2-(2-chloro-4-iodophenylamino)-N-cyclopropylmethoxy-3, 4-difluorobenzamide inhibits the reaction [Prodigiosin results in increased expression of SQSTM1 protein] CTD PMID:31077745 progesterone increases expression ISO RGD:736484 6480464 Progesterone results in increased expression of SQSTM1 mRNA CTD PMID:18037150 promethazine increases expression ISO RGD:736484 6480464 Promethazine results in increased expression of SQSTM1 protein CTD PMID:31682805 pterostilbene multiple interactions ISO RGD:736485 6480464 pterostilbene inhibits the reaction [Ethanol results in increased expression of SQSTM1 protein], SESN2 protein promotes the reaction [pterostilbene inhibits the reaction [Ethanol results in increased expression of SQSTM1 protein]] CTD PMID:34405320 pterostilbene multiple interactions ISO RGD:736484 6480464 bafilomycin A1 inhibits the reaction [pterostilbene inhibits the reaction [Ethanol results in increased expression of SQSTM1 protein]] more ... CTD PMID:34405320 puerarin multiple interactions EXP 6480464 puerarin inhibits the reaction [lead nitrate results in increased expression of SQSTM1 protein], puerarin promotes the reaction [cadmium acetate results in increased expression of SQSTM1 protein] CTD PMID:27762461 , PMID:34897960 Pyridostigmine bromide multiple interactions EXP 6480464 [Pyridostigmine Bromide co-treated with DEET co-treated with Permethrin] results in increased expression of SQSTM1 mRNA CTD PMID:28659758 pyrovalerone multiple interactions ISO RGD:736484 6480464 Acetylcysteine inhibits the reaction [pyrovalerone analog results in decreased expression of SQSTM1 protein] CTD PMID:28578026 pyrovalerone decreases expression ISO RGD:736484 6480464 pyrovalerone analog results in decreased expression of SQSTM1 protein CTD PMID:28578026 quercetin multiple interactions ISO RGD:736484 6480464 3-methyladenine inhibits the reaction [Quercetin results in decreased expression of SQSTM1 protein] more ... CTD PMID:25881548 , PMID:28251795 quercetin affects phosphorylation ISO RGD:736484 6480464 Quercetin affects the phosphorylation of SQSTM1 protein CTD PMID:35688186 quercetin increases expression ISO RGD:736484 6480464 Quercetin results in increased expression of SQSTM1 mRNA CTD PMID:21632981 , PMID:26198647 quinolinic acid multiple interactions EXP 6480464 Quinolinic Acid promotes the reaction [SQSTM1 protein binds to KEAP1 protein] CTD PMID:30876764 rac-lactic acid increases expression ISO RGD:736484 6480464 Lactic Acid results in increased expression of SQSTM1 mRNA CTD PMID:30851411 radon atom increases expression ISO RGD:736485 6480464 Radon results in increased expression of SQSTM1 protein CTD PMID:33107683 radon atom multiple interactions ISO RGD:736485 6480464 Melatonin inhibits the reaction [Radon results in increased expression of SQSTM1 protein] CTD PMID:33107683 radon(0) increases expression ISO RGD:736485 6480464 Radon results in increased expression of SQSTM1 protein CTD PMID:33107683 radon(0) multiple interactions ISO RGD:736485 6480464 Melatonin inhibits the reaction [Radon results in increased expression of SQSTM1 protein] CTD PMID:33107683 raloxifene increases expression EXP 6480464 Raloxifene Hydrochloride results in increased expression of SQSTM1 mRNA CTD PMID:15576828 reserpine increases expression ISO RGD:736484 6480464 Reserpine results in increased expression of SQSTM1 mRNA CTD PMID:26198647 resveratrol multiple interactions ISO RGD:736484 6480464 3-methyladenine inhibits the reaction [resveratrol results in increased degradation of SQSTM1 protein] more ... CTD PMID:21778691 more ... resveratrol increases expression ISO RGD:736484 6480464 resveratrol results in increased expression of SQSTM1 protein CTD PMID:21778691 resveratrol decreases expression ISO RGD:736484 6480464 resveratrol results in decreased expression of SQSTM1 protein CTD PMID:24451142 resveratrol multiple interactions EXP 6480464 Chloroquine promotes the reaction [Resveratrol promotes the reaction [Glucose results in increased expression of SQSTM1 protein]] more ... CTD PMID:24889822 more ... resveratrol increases expression ISO RGD:736485 6480464 resveratrol results in increased expression of SQSTM1 protein CTD PMID:25505154 resveratrol multiple interactions ISO RGD:736485 6480464 bafilomycin A1 inhibits the reaction [resveratrol inhibits the reaction [Streptozocin results in increased expression of SQSTM1 protein]] more ... CTD PMID:24304514 , PMID:24889822 resveratrol increases degradation ISO RGD:736484 6480464 resveratrol results in increased degradation of SQSTM1 protein CTD PMID:24145604 , PMID:25943029 retinyl acetate increases expression ISO RGD:736485 6480464 retinol acetate results in increased expression of SQSTM1 mRNA CTD PMID:16772331 Rhein increases expression ISO RGD:736484 6480464 rhein results in increased expression of SQSTM1 protein CTD PMID:31436023 rifampicin increases expression ISO RGD:736484 6480464 Rifampin results in increased expression of SQSTM1 protein CTD PMID:29908302 Riluzole multiple interactions ISO RGD:736484 6480464 Riluzole promotes the reaction [AR protein binds to SQSTM1 protein] CTD PMID:30280407 Ro 31-8220 multiple interactions ISO RGD:736484 6480464 Ro 31-8220 inhibits the reaction [SQSTM1 protein results in increased expression of NQO1 protein] CTD PMID:17360324 rotenone decreases response to substance ISO RGD:736484 6480464 SQSTM1 protein results in decreased susceptibility to Rotenone CTD PMID:17360324 rotenone decreases expression ISO RGD:736484 6480464 Rotenone results in decreased expression of SQSTM1 protein CTD PMID:30673822 , PMID:31926197 rotenone increases expression EXP 6480464 Rotenone results in increased expression of SQSTM1 mRNA, Rotenone results in increased expression of SQSTM1 protein CTD PMID:28374803 , PMID:33137417 rotenone multiple interactions EXP 6480464 7-methyl-5-(1-((3-(trifluoromethyl)phenyl)acetyl)-2 more ... CTD PMID:25725130 more ... rotenone decreases expression EXP 6480464 Rotenone results in decreased expression of SQSTM1 protein CTD PMID:24036476 more ... rotenone increases expression ISO RGD:736484 6480464 Rotenone results in increased expression of SQSTM1 mRNA, Rotenone results in increased expression of SQSTM1 protein CTD PMID:24451142 , PMID:36586010 rotenone multiple interactions ISO RGD:736484 6480464 bafilomycin A inhibits the reaction [Resveratrol inhibits the reaction [Rotenone results in increased expression of SQSTM1 protein]] more ... CTD PMID:24451142 more ... rotenone multiple interactions ISO RGD:736485 6480464 [bafilomycin A1 co-treated with Rotenone] results in increased expression of SQSTM1 protein, SESN2 protein inhibits the reaction [Rotenone results in increased expression of SQSTM1 protein] CTD PMID:26031332 rotenone increases expression ISO RGD:736485 6480464 Rotenone results in increased expression of SQSTM1 mRNA, Rotenone results in increased expression of SQSTM1 protein CTD PMID:19304788 , PMID:26031332 S-(1,2-dichlorovinyl)-L-cysteine increases expression ISO RGD:736484 6480464 S-(1, 2-dichlorovinyl)cysteine results in increased expression of SQSTM1 mRNA CTD PMID:33725128 S-(1,2-dichlorovinyl)-L-cysteine multiple interactions ISO RGD:736484 6480464 [S-(1, 2-dichlorovinyl)cysteine co-treated with Lipopolysaccharides] results in increased expression of SQSTM1 mRNA CTD PMID:35811015 salubrinal multiple interactions ISO RGD:736484 6480464 salubrinal inhibits the reaction [Cadmium Chloride results in decreased expression of SQSTM1 protein] more ... CTD PMID:20929985 , PMID:33127495 SB 203580 multiple interactions EXP 6480464 SB 203580 inhibits the reaction [fenvalerate results in decreased expression of SQSTM1 protein] CTD PMID:31734597 SB 431542 multiple interactions ISO RGD:736484 6480464 [LDN 193189 co-treated with 4-(5-benzo(1 more ... CTD PMID:27188386 , PMID:34480604 SB-239063 multiple interactions EXP 6480464 [[Oxygen deficiency co-treated with Blood Glucose deficiency] results in increased susceptibility to SB 239063] which results in increased expression of SQSTM1 protein CTD PMID:26116440 SCH772984 multiple interactions ISO RGD:736484 6480464 SCH772984 inhibits the reaction [pachastrissamine analog promotes the reaction [KEAP1 protein binds to SQSTM1 protein]], SCH772984 inhibits the reaction [pachastrissamine analog results in increased expression of SQSTM1 protein] CTD PMID:35123989 Securinine increases expression ISO RGD:736484 6480464 securinine results in increased expression of SQSTM1 mRNA CTD PMID:32662633 selenium atom multiple interactions EXP 6480464 Selenium inhibits the reaction [arsenite results in increased expression of SQSTM1 protein] CTD PMID:29324385 sepantronium decreases expression ISO RGD:736484 6480464 sepantronium results in decreased expression of SQSTM1 protein CTD PMID:31837377 sepantronium multiple interactions ISO RGD:736484 6480464 3-methyladenine inhibits the reaction [sepantronium results in decreased expression of SQSTM1 protein] more ... CTD PMID:31837377 sevoflurane multiple interactions EXP 6480464 MIR204 mRNA affects the reaction [Sevoflurane results in decreased expression of SQSTM1 protein], VCAM1 protein affects the reaction [MIR204 mRNA affects the reaction [Sevoflurane results in decreased expression of SQSTM1 protein]] CTD PMID:36177783 sevoflurane decreases expression ISO RGD:736484 6480464 Sevoflurane results in decreased expression of SQSTM1 protein CTD PMID:35472370 sevoflurane decreases expression EXP 6480464 Sevoflurane results in decreased expression of SQSTM1 protein CTD PMID:36177783 silicon dioxide increases expression ISO RGD:736484 6480464 Silicon Dioxide analog results in increased expression of SQSTM1 mRNA, Silicon Dioxide results in increased expression of SQSTM1 mRNA CTD PMID:23806026 more ... silicon dioxide decreases expression ISO RGD:736484 6480464 Silicon Dioxide results in decreased expression of SQSTM1 protein CTD PMID:32061152 silicon dioxide multiple interactions ISO RGD:736484 6480464 3-methyladenine inhibits the reaction [Silicon Dioxide results in decreased expression of SQSTM1 protein] more ... CTD PMID:30698894 , PMID:32061152 silicon dioxide multiple interactions ISO RGD:736485 6480464 GAS6 gene mutant form inhibits the reaction [Silicon Dioxide results in increased expression of SQSTM1 mRNA] more ... CTD PMID:33232774 silicon dioxide increases expression ISO RGD:736485 6480464 Silicon Dioxide results in increased expression of SQSTM1 mRNA, Silicon Dioxide results in increased expression of SQSTM1 protein CTD PMID:19073995 more ... silver atom increases expression ISO RGD:736484 6480464 Silver results in increased expression of SQSTM1 mRNA, Silver results in increased expression of SQSTM1 protein CTD PMID:26014281 more ... silver atom increases expression ISO RGD:736485 6480464 Silver results in increased expression of SQSTM1 mRNA CTD PMID:27131904 silver(0) increases expression ISO RGD:736484 6480464 Silver results in increased expression of SQSTM1 mRNA, Silver results in increased expression of SQSTM1 protein CTD PMID:26014281 more ... silver(0) increases expression ISO RGD:736485 6480464 Silver results in increased expression of SQSTM1 mRNA CTD PMID:27131904 simvastatin multiple interactions ISO RGD:736484 6480464 [Simvastatin co-treated with Metformin] results in decreased expression of SQSTM1 protein, Chloroquine inhibits the reaction [[Simvastatin co-treated with Metformin] results in decreased expression of SQSTM1 protein] CTD PMID:25412314 sirolimus multiple interactions ISO RGD:736485 6480464 [Sirolimus co-treated with gelsenicine] results in decreased expression of SQSTM1 protein more ... CTD PMID:24238063 more ... sirolimus increases degradation ISO RGD:736484 6480464 Sirolimus results in increased degradation of SQSTM1 protein CTD PMID:28025121 sirolimus increases expression ISO RGD:736484 6480464 Sirolimus results in increased expression of SQSTM1 protein CTD PMID:30338810 sirolimus decreases expression EXP 6480464 Sirolimus results in decreased expression of SQSTM1 protein CTD PMID:29218509 sirolimus multiple interactions EXP 6480464 [Sirolimus co-treated with cadmium acetate] results in decreased expression of SQSTM1 mRNA more ... CTD PMID:29128638 more ... sirolimus decreases expression ISO RGD:736484 6480464 Sirolimus results in decreased expression of SQSTM1 protein CTD PMID:19773376 more ... sirolimus multiple interactions ISO RGD:736484 6480464 [AICA ribonucleotide co-treated with Sirolimus] results in increased expression of SQSTM1 protein more ... CTD PMID:24304514 more ... sirolimus decreases expression ISO RGD:736485 6480464 Sirolimus results in decreased expression of SQSTM1 protein CTD PMID:24238063 more ... sirtinol multiple interactions EXP 6480464 sirtinol inhibits the reaction [resveratrol inhibits the reaction [Hydrogen Peroxide results in increased expression of SQSTM1 protein]], sirtinol promotes the reaction [Hydrogen Peroxide results in increased expression of SQSTM1 protein] CTD PMID:24889822 SKF-96365 hydrochloride multiple interactions EXP 6480464 1-(2-(3-(4-methoxyphenyl)propoxy)-4-methoxyphenylethyl)-1H-imidazole inhibits the reaction [2 more ... CTD PMID:32895711 sodium arsenate increases expression ISO RGD:736485 6480464 sodium arsenate results in increased expression of SQSTM1 mRNA, sodium arsenate results in increased expression of SQSTM1 protein alternative form CTD PMID:12745069 sodium arsenate multiple interactions ISO RGD:736484 6480464 [sodium arsenate results in increased abundance of Arsenic] which results in increased expression of and results in increased phosphorylation of SQSTM1 protein more ... CTD PMID:32525701 sodium arsenite multiple interactions ISO RGD:736484 6480464 [sodium arsenite results in increased abundance of Arsenic] which results in decreased expression of SQSTM1 protein more ... CTD PMID:23589329 more ... sodium arsenite decreases expression ISO RGD:736484 6480464 sodium arsenite results in decreased expression of SQSTM1 mRNA, sodium arsenite results in decreased expression of SQSTM1 protein CTD PMID:34032870 , PMID:35750204 sodium arsenite multiple interactions EXP 6480464 [[sodium arsenite results in increased abundance of Arsenic] co-treated with [Sodium Fluoride results in increased abundance of Fluorides]] results in increased expression of SQSTM1 mRNA more ... CTD PMID:31844926 sodium arsenite increases expression EXP 6480464 sodium arsenite results in increased expression of SQSTM1 protein CTD PMID:30551535 sodium arsenite increases expression ISO RGD:736485 6480464 sodium arsenite results in increased expression of SQSTM1 mRNA more ... CTD PMID:11525245 more ... sodium arsenite multiple interactions ISO RGD:736485 6480464 ATG7 gene mutant form inhibits the reaction [sodium arsenite results in increased degradation of SQSTM1 protein] more ... CTD PMID:26483381 more ... sodium arsenite increases response to substance ISO RGD:736484 6480464 SQSTM1 protein results in increased susceptibility to sodium arsenite CTD PMID:23589329 sodium arsenite increases expression ISO RGD:736484 6480464 sodium arsenite results in increased expression of SQSTM1 mRNA, sodium arsenite results in increased expression of SQSTM1 protein CTD PMID:24516582 more ... sodium dichromate increases expression EXP 6480464 sodium bichromate results in increased expression of SQSTM1 mRNA CTD PMID:22110744 sodium dichromate decreases expression ISO RGD:736485 6480464 sodium bichromate results in decreased expression of SQSTM1 mRNA CTD PMID:22155349 sodium dichromate increases expression ISO RGD:736485 6480464 sodium bichromate results in increased expression of SQSTM1 mRNA CTD PMID:22155349 sodium fluoride multiple interactions ISO RGD:736485 6480464 4 more ... CTD PMID:29505816 , PMID:34536393 sodium fluoride multiple interactions EXP 6480464 [[sodium arsenite results in increased abundance of Arsenic] co-treated with [Sodium Fluoride results in increased abundance of Fluorides]] results in increased expression of SQSTM1 mRNA more ... CTD PMID:31844926 sodium fluoride affects expression ISO RGD:736485 6480464 Sodium Fluoride affects the expression of SQSTM1 protein CTD PMID:30225638 sodium fluoride decreases expression ISO RGD:736485 6480464 Sodium Fluoride results in decreased expression of SQSTM1 mRNA, Sodium Fluoride results in decreased expression of SQSTM1 protein CTD PMID:29505816 more ... Soman increases expression EXP 6480464 Soman results in increased expression of SQSTM1 protein CTD PMID:31102696 sorafenib multiple interactions ISO RGD:736484 6480464 bafilomycin A1 inhibits the reaction [Sorafenib results in decreased expression of SQSTM1 protein], Chloroquine inhibits the reaction [Sorafenib results in decreased expression of SQSTM1 protein] CTD PMID:21858812 sorafenib decreases expression ISO RGD:736484 6480464 Sorafenib results in decreased expression of SQSTM1 protein CTD PMID:21858812 stilbenoid decreases expression ISO RGD:736484 6480464 Stilbenes results in decreased expression of SQSTM1 protein CTD PMID:23059970 streptozocin increases expression ISO RGD:736485 6480464 Streptozocin results in increased expression of SQSTM1 protein CTD PMID:24889822 , PMID:30459625 streptozocin multiple interactions EXP 6480464 [Dietary Fats co-treated with Streptozocin co-treated with Carbamazepine] results in decreased expression of SQSTM1 protein, [Dietary Fats co-treated with Streptozocin] results in increased expression of SQSTM1 protein CTD PMID:35786680 streptozocin multiple interactions ISO RGD:736485 6480464 bafilomycin A1 inhibits the reaction [Resveratrol inhibits the reaction [Streptozocin results in increased expression of SQSTM1 protein]] more ... CTD PMID:24889822 , PMID:30459625 succimer multiple interactions ISO RGD:736485 6480464 [Succimer binds to Magnetite Nanoparticles] which results in increased expression of SQSTM1 mRNA, [Succimer co-treated with Magnetite Nanoparticles] results in increased expression of SQSTM1 mRNA CTD PMID:21641980 , PMID:26378955 sulforaphane multiple interactions ISO RGD:736484 6480464 sulforaphane inhibits the reaction [sodium arsenite affects the localization of SQSTM1 protein] CTD PMID:23589329 sulforaphane decreases expression ISO RGD:736484 6480464 sulforaphane results in decreased expression of SQSTM1 mRNA CTD PMID:35724838 sulforaphane increases expression ISO RGD:736485 6480464 sulforaphane results in increased expression of SQSTM1 protein CTD PMID:29950142 sulforaphane multiple interactions ISO RGD:736485 6480464 NFE2L2 protein affects the reaction [sulforaphane results in increased expression of SQSTM1 protein] CTD PMID:29950142 sulforaphane increases expression ISO RGD:736484 6480464 sulforaphane results in increased expression of SQSTM1 mRNA, sulforaphane results in increased expression of SQSTM1 protein CTD PMID:31838189 , PMID:33894213 sulindac increases expression ISO RGD:736484 6480464 Sulindac results in increased expression of SQSTM1 mRNA CTD PMID:11906190 sulindac sulfide increases expression ISO RGD:736484 6480464 sulindac sulfide results in increased expression of SQSTM1 mRNA CTD PMID:16184548 sunitinib multiple interactions ISO RGD:736485 6480464 Chloroquine inhibits the reaction [sunitinib results in decreased expression of SQSTM1 protein] CTD PMID:24751611 sunitinib decreases expression ISO RGD:736485 6480464 sunitinib results in decreased expression of SQSTM1 protein CTD PMID:24751611 swainsonine increases expression ISO RGD:736485 6480464 Swainsonine results in increased expression of SQSTM1 mRNA, Swainsonine results in increased expression of SQSTM1 protein CTD PMID:36402259 swainsonine multiple interactions ISO RGD:736485 6480464 [bafilomycin A1 co-treated with Swainsonine] results in increased expression of SQSTM1 mRNA, [bafilomycin A1 co-treated with Swainsonine] results in increased lipidation of SQSTM1 protein CTD PMID:36402259 syringic acid increases expression ISO RGD:736484 6480464 syringic acid analog results in increased expression of SQSTM1 protein CTD PMID:34523043 syringin decreases expression ISO RGD:736484 6480464 syringin results in decreased expression of SQSTM1 protein CTD PMID:35580997 T-2 toxin increases expression ISO RGD:736484 6480464 T-2 Toxin results in increased expression of SQSTM1 mRNA CTD PMID:34581912 T-2 toxin increases expression ISO RGD:736485 6480464 T-2 Toxin results in increased expression of SQSTM1 protein CTD PMID:35289972 tamoxifen affects expression ISO RGD:736485 6480464 Tamoxifen affects the expression of SQSTM1 mRNA CTD PMID:17555576 tamoxifen increases expression ISO RGD:736484 6480464 Tamoxifen results in increased expression of SQSTM1 protein CTD PMID:25301941 taurine multiple interactions ISO RGD:736484 6480464 Taurine inhibits the reaction [Arsenic Trioxide results in decreased expression of SQSTM1 protein] CTD PMID:30237538 more ... taurine multiple interactions EXP 6480464 Taurine inhibits the reaction [Arsenic Trioxide results in increased expression of SQSTM1 protein] CTD PMID:30551535 taurine multiple interactions ISO RGD:736485 6480464 Taurine inhibits the reaction [Arsenic Trioxide results in decreased expression of SQSTM1 protein] CTD PMID:30237538 , PMID:30677399 taurocholic acid increases expression ISO RGD:736485 6480464 Taurocholic Acid results in increased expression of SQSTM1 protein CTD PMID:24189133 Temsirolimus multiple interactions ISO RGD:736485 6480464 temsirolimus inhibits the reaction [Dronabinol results in increased expression of SQSTM1 protein] CTD PMID:32773031 tert-butyl hydroperoxide increases expression ISO RGD:736484 6480464 tert-Butylhydroperoxide results in increased expression of SQSTM1 mRNA CTD PMID:23410634 testosterone enanthate affects expression ISO RGD:736484 6480464 testosterone enanthate affects the expression of SQSTM1 mRNA CTD PMID:17440010 tetrachloromethane increases expression ISO RGD:736485 6480464 Carbon Tetrachloride results in increased expression of SQSTM1 mRNA, Carbon Tetrachloride results in increased expression of SQSTM1 protein CTD PMID:27339419 , PMID:31919559 tetrachloromethane multiple interactions ISO RGD:736485 6480464 [TRP53BP2 protein affects the susceptibility to Carbon Tetrachloride] which affects the expression of SQSTM1 protein more ... CTD PMID:31513885 , PMID:35405287 tetrachloromethane increases expression EXP 6480464 Carbon Tetrachloride results in increased expression of SQSTM1 mRNA, Carbon Tetrachloride results in increased expression of SQSTM1 protein CTD PMID:26882442 , PMID:31150632 tetrachloromethane multiple interactions EXP 6480464 Melatonin inhibits the reaction [Carbon Tetrachloride results in increased expression of SQSTM1 protein], schizandrin B inhibits the reaction [Carbon Tetrachloride results in increased expression of SQSTM1 mRNA] CTD PMID:26882442 , PMID:31150632 thiamine(1+) chloride multiple interactions EXP 6480464 Thiamine inhibits the reaction [citreoviridin results in decreased expression of SQSTM1 protein] CTD PMID:31419397 thiamine(1+) chloride multiple interactions ISO RGD:736485 6480464 Thiamine inhibits the reaction [citreoviridin results in decreased expression of SQSTM1 protein] CTD PMID:31419397 thioacetamide increases expression EXP 6480464 Thioacetamide results in increased expression of SQSTM1 mRNA CTD PMID:34492290 thiram increases expression ISO RGD:736484 6480464 Thiram results in increased expression of SQSTM1 mRNA CTD PMID:24211530 thymol multiple interactions ISO RGD:736485 6480464 Thymol inhibits the reaction [Ethanol results in increased expression of SQSTM1 protein] CTD PMID:36535314 thymol sulfate(1-) multiple interactions ISO RGD:736485 6480464 Thymol inhibits the reaction [Ethanol results in increased expression of SQSTM1 protein] CTD PMID:36535314 titanium dioxide increases expression ISO RGD:736484 6480464 titanium dioxide results in increased expression of SQSTM1 mRNA, titanium dioxide results in increased expression of SQSTM1 protein CTD PMID:30273564 toosendanin decreases expression ISO RGD:736484 6480464 toosendanin results in decreased expression of SQSTM1 protein CTD PMID:34742683 topotecan multiple interactions EXP 6480464 [oxaliplatin co-treated with Topotecan] results in increased expression of SQSTM1 mRNA CTD PMID:25729387 trametinib decreases expression ISO RGD:736484 6480464 trametinib results in decreased expression of SQSTM1 protein CTD PMID:30339727 trans-piceid multiple interactions ISO RGD:736484 6480464 polydatin promotes the reaction [Rotenone results in decreased expression of SQSTM1 protein] CTD PMID:31926197 triacsin C increases expression ISO RGD:736484 6480464 triacsin C results in increased expression of SQSTM1 mRNA CTD PMID:16704987 tributylstannane increases expression ISO RGD:736484 6480464 tributyltin results in increased expression of SQSTM1 protein CTD PMID:36319700 tributylstannane increases expression ISO RGD:736485 6480464 tributyltin results in increased expression of SQSTM1 protein CTD PMID:36319700 trichloroethene multiple interactions ISO RGD:736485 6480464 PPARA protein inhibits the reaction [Trichloroethylene results in decreased expression of SQSTM1 mRNA] CTD PMID:15363585 trichloroethene increases expression EXP 6480464 Trichloroethylene results in increased expression of SQSTM1 mRNA, Trichloroethylene results in increased expression of SQSTM1 protein CTD PMID:33387578 , PMID:33636387 trimethyltin decreases degradation EXP 6480464 trimethyltin results in decreased degradation of SQSTM1 protein CTD PMID:26459185 troglitazone increases expression ISO RGD:736484 6480464 troglitazone results in increased expression of SQSTM1 mRNA CTD PMID:19140230 Tungsten carbide multiple interactions ISO RGD:736484 6480464 [tungsten carbide co-treated with Cobalt] results in increased expression of SQSTM1 mRNA CTD PMID:18078969 tunicamycin increases expression ISO RGD:736484 6480464 Tunicamycin results in increased expression of SQSTM1 mRNA CTD PMID:22378314 tunicamycin multiple interactions ISO RGD:736485 6480464 [ATG5 protein mutant form results in increased susceptibility to Tunicamycin] which results in increased expression of SQSTM1 protein CTD PMID:29793971 tunicamycin decreases expression ISO RGD:736484 6480464 Tunicamycin results in decreased expression of SQSTM1 mRNA, Tunicamycin results in decreased expression of SQSTM1 protein CTD PMID:25979647 , PMID:36586010 urethane increases expression ISO RGD:736484 6480464 Urethane results in increased expression of SQSTM1 mRNA CTD PMID:28818685 usnic acid increases degradation ISO RGD:736484 6480464 usnic acid results in increased degradation of SQSTM1 protein CTD PMID:25078063 valproic acid increases methylation ISO RGD:736484 6480464 Valproic Acid results in increased methylation of SQSTM1 gene CTD PMID:29154799 valproic acid affects expression ISO RGD:736484 6480464 Valproic Acid affects the expression of SQSTM1 mRNA CTD PMID:25979313 valproic acid increases expression ISO RGD:736484 6480464 Valproic Acid results in increased expression of SQSTM1 mRNA CTD PMID:23179753 more ... valproic acid affects expression ISO RGD:736485 6480464 Valproic Acid affects the expression of SQSTM1 mRNA CTD PMID:17292431 valsartan multiple interactions EXP 6480464 Valsartan inhibits the reaction [Doxorubicin results in decreased expression of SQSTM1 protein] CTD PMID:34273911 vancomycin multiple interactions ISO RGD:736485 6480464 [Vancomycin co-treated with Neomycin co-treated with Metronidazole] promotes the reaction [Zinc Oxide analog results in increased expression of SQSTM1 protein] CTD PMID:36535435 venetoclax multiple interactions ISO RGD:736484 6480464 4-(4-fluorophenyl)-2-(4-hydroxyphenyl)-5-(4-pyridyl)imidazole inhibits the reaction [[venetoclax co-treated with WEHI-539 co-treated with hydroquinone] results in decreased expression of SQSTM1 protein] more ... CTD PMID:35561756 venlafaxine hydrochloride decreases expression EXP 6480464 Venlafaxine Hydrochloride results in decreased expression of SQSTM1 mRNA CTD PMID:25423262 venlafaxine hydrochloride multiple interactions EXP 6480464 Chloroquine inhibits the reaction [Venlafaxine Hydrochloride inhibits the reaction [Rotenone results in decreased expression of SQSTM1 protein]], Venlafaxine Hydrochloride inhibits the reaction [Rotenone results in decreased expression of SQSTM1 protein] CTD PMID:35104487 vincristine multiple interactions ISO RGD:736484 6480464 [cotylenin A co-treated with Vincristine] results in increased degradation of SQSTM1 protein CTD PMID:25672400 vincristine increases expression ISO RGD:736484 6480464 Vincristine results in increased expression of SQSTM1 mRNA CTD PMID:23649840 vismodegib multiple interactions ISO RGD:736484 6480464 HhAntag691 inhibits the reaction [nickel monoxide results in increased expression of SQSTM1 protein] CTD PMID:34608745 vitamin D decreases expression ISO RGD:736484 6480464 Vitamin D results in decreased expression of SQSTM1 protein CTD PMID:30698894 vitamin D multiple interactions ISO RGD:736484 6480464 [Silicon Dioxide co-treated with Vitamin D co-treated with bafilomycin A1] results in increased expression of SQSTM1 protein, [Vitamin D co-treated with bafilomycin A1] results in increased expression of SQSTM1 protein CTD PMID:30698894 wortmannin multiple interactions ISO RGD:736485 6480464 [wortmannin co-treated with Ethanol] results in increased expression of SQSTM1 protein CTD PMID:22459179 wortmannin decreases expression ISO RGD:736485 6480464 wortmannin results in decreased expression of SQSTM1 protein CTD PMID:22459179 wortmannin increases expression ISO RGD:736485 6480464 wortmannin results in increased expression of SQSTM1 protein CTD PMID:22459179 XAV939 multiple interactions ISO RGD:736484 6480464 [[ascorbate-2-phosphate co-treated with Chir 99021 co-treated with XAV939 co-treated with BMP4 protein] co-treated with [INHBA protein binds to INHBA protein]] results in increased expression of SQSTM1 mRNA, [[Ascorbic Acid co-treated with Chir 99021 co-treated with XAV939 co-treated with BMP4 protein co-treated with FGF1 protein co-treated with WNT3A protein co-treated with HGF protein] co-treated with [INHBA protein binds to INHBA protein]] results in increased expression of SQSTM1 mRNA CTD PMID:34480604 zearalenone increases expression EXP 6480464 Zearalenone results in increased expression of SQSTM1 protein CTD PMID:31586597 , PMID:32858132 zearalenone decreases expression ISO RGD:736485 6480464 Zearalenone results in decreased expression of SQSTM1 mRNA, Zearalenone results in decreased expression of SQSTM1 protein CTD PMID:31982503 , PMID:34537261 zidovudine increases expression EXP 6480464 Zidovudine results in increased expression of SQSTM1 protein CTD PMID:29594326 zinc atom multiple interactions ISO RGD:736484 6480464 [PCI 5002 co-treated with Zinc] results in increased expression of SQSTM1 mRNA CTD PMID:18593933 zinc oxide increases expression ISO RGD:736484 6480464 Zinc Oxide results in increased expression of SQSTM1 protein CTD PMID:29289694 zinc oxide decreases expression ISO RGD:736484 6480464 Zinc Oxide results in decreased expression of SQSTM1 protein CTD PMID:34766255 zinc oxide multiple interactions ISO RGD:736485 6480464 [Vancomycin co-treated with Neomycin co-treated with Metronidazole] promotes the reaction [Zinc Oxide analog results in increased expression of SQSTM1 protein] CTD PMID:36535435 zinc oxide increases expression ISO RGD:736485 6480464 Zinc Oxide analog results in increased expression of SQSTM1 protein CTD PMID:36535435 zinc pyrithione multiple interactions ISO RGD:736485 6480464 SQSTM1 protein affects the reaction [pyrithione zinc results in increased expression of NFE2L2 protein] CTD PMID:30261176 zinc(0) multiple interactions ISO RGD:736484 6480464 [PCI 5002 co-treated with Zinc] results in increased expression of SQSTM1 mRNA CTD PMID:18593933
