Sqstm1 (sequestosome 1) - Rat Genome Database

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Gene: Sqstm1 (sequestosome 1) Rattus norvegicus
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Symbol: Sqstm1
Name: sequestosome 1
RGD ID: 69287
Description: Enables identical protein binding activity and protein kinase C binding activity. Involved in positive regulation of protein phosphorylation and response to ischemia. Located in Lewy body. Biomarker of glaucoma and hypertension. Human ortholog(s) of this gene implicated in Paget's disease of bone; Paget's disease of bone 3; distal myopathy with rimmed vacuoles; frontotemporal dementia and/or amyotrophic lateral sclerosis-3; and neurodegeneration with ataxia, dystonia, and gaze palsy, childhood-onset. Orthologous to human SQSTM1 (sequestosome 1); PARTICIPATES IN interleukin-1 signaling pathway; mitochondrial autophagy pathway; nuclear factor, erythroid 2 like 2 signaling pathway; INTERACTS WITH (+)-schisandrin B; (-)-anisomycin; 1,3-dichloropropan-2-ol.
Type: protein-coding
RefSeq Status: VALIDATED
Previously known as: induced oxidative stress-like; Osi; oxidative stress induced; PKC-zeta-interacting protein; protein kinase C-zeta-interacting protein; sequestosome-1; ubiquitin-binding protein p62; ZIP; ZIP3
RGD Orthologs
Human
Mouse
Chinchilla
Bonobo
Dog
Squirrel
Pig
Green Monkey
Naked Mole-Rat
Alliance Genes
More Info more info ...
Latest Assembly: mRatBN7.2 - mRatBN7.2 Assembly
Position:
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr81035,026,598 - 35,037,750 (-)NCBIGRCr8
mRatBN7.21034,525,517 - 34,536,670 (-)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl1034,525,519 - 34,536,673 (-)EnsemblmRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx1039,200,880 - 39,212,041 (-)NCBIRnor_SHRUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.0107,740,133 - 7,751,294 (-)NCBIRnor_SHRSPUTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.01034,194,553 - 34,205,714 (-)NCBIRnor_WKYUTH_Rnor_WKY_Bbb_1.0
Rnor_6.01035,704,728 - 35,716,316 (-)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl1035,704,730 - 35,716,294 (-)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.01035,463,172 - 35,474,754 (-)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.41035,751,300 - 35,762,630 (-)NCBIRGSC3.4RGSC_v3.4rn4RGSC3.4
RGSC_v3.11035,752,706 - 35,763,676 (-)NCBI
Celera1033,874,680 - 33,885,832 (-)NCBICelera
Cytogenetic Map10q22NCBI
JBrowse: View Region in Genome Browser (JBrowse)
Model


Gene-Chemical Interaction Annotations     Click to see Annotation Detail View
(+)-schisandrin B  (EXP)
(+)-Tetrandrine  (ISO)
(-)-anisomycin  (EXP,ISO)
(-)-epigallocatechin 3-gallate  (ISO)
(1->4)-beta-D-glucan  (ISO)
(20S)-ginsenoside Rg3  (ISO)
(S)-nicotine  (ISO)
(S)-ropivacaine  (ISO)
1,2-dichloroethane  (ISO)
1,2-dimethylhydrazine  (ISO)
1,3-benzothiazole-2-thiol  (ISO)
1,3-dichloropropan-2-ol  (EXP)
1,4-benzoquinone  (ISO)
1-monopalmitoylglycerol  (ISO)
17alpha-ethynylestradiol  (EXP,ISO)
17beta-estradiol  (ISO)
2,2',4,4'-Tetrabromodiphenyl ether  (EXP,ISO)
2,2',5,5'-tetrachlorobiphenyl  (EXP,ISO)
2,3',4,4',5-Pentachlorobiphenyl  (EXP)
2,3,7,8-tetrachlorodibenzodioxine  (EXP,ISO)
2,4,6-trinitrobenzenesulfonic acid  (EXP)
2,4-D  (EXP,ISO)
2,4-dibromophenyl 2,4,5-tribromophenyl ether  (ISO)
2-(chloromethyl)pyridine  (ISO)
2-(tert-butylimino)-5-phenyl-3-(propan-2-yl)-1,3,5-thiadiazinan-4-one  (ISO)
2-butoxyethanol  (ISO)
2-deoxy-D-glucose  (ISO)
2-hydroxyethyl methacrylate  (ISO)
2-hydroxypropanoic acid  (ISO)
2-methoxyethanol  (EXP)
2-tert-butylhydroquinone  (EXP,ISO)
20-hydroxyecdysone  (ISO)
3,3',5,5'-tetrabromobisphenol A  (ISO)
3,3',5-triiodo-L-thyronine  (ISO)
3,4-methylenedioxymethamphetamine  (EXP,ISO)
3-chloropropane-1,2-diol  (EXP,ISO)
3-isobutyl-1-methyl-7H-xanthine  (ISO)
3-methyladenine  (EXP,ISO)
3-phenylprop-2-enal  (ISO)
3H-1,2-dithiole-3-thione  (EXP)
4'-epidoxorubicin  (EXP)
4,4'-diisothiocyano-trans-stilbene-2,2'-disulfonic acid  (ISO)
4,4'-methylene-bis-(2-chloroaniline)  (ISO)
4,4'-sulfonyldiphenol  (EXP,ISO)
4-amino-2,6-dinitrotoluene  (EXP)
4-hydroxynon-2-enal  (ISO)
4-methoxy-TEMPO  (ISO)
4-nitro-1,2-phenylenediamine  (ISO)
4-phenylbutyric acid  (ISO)
5-aza-2'-deoxycytidine  (ISO)
5-chloro-7-iodoquinolin-8-ol  (ISO)
6-chloro-2,3,4,9-tetrahydro-1H-carbazole-1-carboxamide  (ISO)
7,9-dihydro-1H-purine-2,6,8(3H)-trione  (ISO)
7beta-aminocephalosporanic acid  (ISO)
abamectin  (ISO)
ABT-737  (ISO)
acarbose  (ISO)
acetaldehyde  (ISO)
acetylcholine  (ISO)
acrolein  (EXP,ISO)
acrylamide  (EXP,ISO)
actinomycin D  (ISO)
Aescin  (ISO)
aflatoxin B1  (ISO)
AICA ribonucleotide  (ISO)
Ajugasterone C  (ISO)
aldehydo-D-glucose  (EXP,ISO)
alginic acid  (ISO)
all-trans-retinoic acid  (ISO)
allethrin  (ISO)
aloxistatin  (ISO)
alpha,alpha-trehalose  (ISO)
alpha-amanitin  (ISO)
alpha-D-galactose  (EXP,ISO)
alpha-pinene  (ISO)
Alpinetin  (ISO)
aluminium atom  (ISO)
aluminium(0)  (ISO)
amiodarone  (ISO)
ammonium chloride  (EXP,ISO)
ammonium hexachloroplatinate  (ISO)
andrographolide  (ISO)
Anemoside B4  (ISO)
anthra[1,9-cd]pyrazol-6(2H)-one  (EXP,ISO)
antimonite  (ISO)
antimycin A  (ISO)
antirheumatic drug  (ISO)
aprepitant  (EXP)
arachidonic acid  (ISO)
aristolochic acid A  (ISO)
arotinoid acid  (ISO)
arsane  (EXP,ISO)
arsenic atom  (EXP,ISO)
arsenite(3-)  (EXP,ISO)
arsenous acid  (EXP,ISO)
artesunate  (ISO)
astemizole  (EXP)
astragaloside IV  (EXP)
atazanavir sulfate  (ISO)
atorvastatin calcium  (EXP)
atrazine  (EXP,ISO)
avobenzone  (ISO)
azathioprine  (ISO)
bafilomycin A1  (EXP,ISO)
Bafilomycin B1  (ISO)
BAPTA  (ISO)
Bardoxolone methyl  (ISO)
benzidine  (ISO)
benzo[a]pyrene  (EXP,ISO)
berberine  (ISO)
beta-naphthoflavone  (ISO)
beta-thujaplicin  (ISO)
bexarotene  (EXP)
bicalutamide  (ISO)
bis(2-chloroethyl) sulfide  (ISO)
bis(2-ethylhexyl) phthalate  (EXP,ISO)
bisphenol A  (EXP,ISO)
bisphenol F  (EXP)
bortezomib  (EXP,ISO)
brazilin  (ISO)
Brusatol  (EXP)
buprofezin  (ISO)
butachlor  (ISO)
butane-2,3-dione  (ISO)
butyric acid  (ISO)
cadmium atom  (EXP,ISO)
cadmium dichloride  (EXP,ISO)
caffeine  (EXP,ISO)
calcium atom  (EXP)
calcium(0)  (EXP)
camptothecin  (ISO)
cannabidiol  (ISO)
capivasertib  (ISO)
carbamazepine  (EXP,ISO)
carbon disulfide  (EXP,ISO)
carbon nanotube  (ISO)
carglumic acid  (ISO)
CCCP  (ISO)
celastrol  (EXP)
celecoxib  (ISO)
cerium trichloride  (ISO)
chenodeoxycholic acid  (ISO)
CHIR 99021  (ISO)
chloroacetaldehyde  (ISO)
chlorogenic acid  (ISO)
chloropicrin  (ISO)
chloroquine  (EXP,ISO)
chlorpyrifos  (EXP,ISO)
cholesterol  (ISO)
cholic acid  (ISO)
chromium(6+)  (ISO)
ciglitazone  (ISO)
ciprofibrate  (ISO)
cisplatin  (EXP,ISO)
Citreoviridin  (EXP,ISO)
clofibrate  (ISO)
clozapine  (ISO)
cobalt atom  (ISO)
cobalt dichloride  (EXP,ISO)
cocaine  (ISO)
coenzyme Q10  (ISO)
colforsin daropate hydrochloride  (ISO)
colistin  (EXP)
copper atom  (ISO)
copper(0)  (ISO)
copper(II) chloride  (ISO)
copper(II) sulfate  (ISO)
corosolic acid  (EXP,ISO)
cortisol  (ISO)
Corynoxine B  (ISO)
coumarin  (ISO)
coumestrol  (ISO)
crocidolite asbestos  (ISO)
Cryptotanshinone  (ISO)
cucurbitacin E  (ISO)
curcumin  (ISO)
Curcumol  (EXP)
cycloheximide  (ISO)
cyclosporin A  (EXP,ISO)
cyfluthrin  (EXP,ISO)
cylindrospermopsin  (ISO)
cypermethrin  (ISO)
D-glucose  (EXP,ISO)
dactolisib  (ISO)
dapagliflozin  (EXP)
DDT  (ISO)
decabromodiphenyl ether  (ISO)
deguelin  (ISO)
deoxycholic acid  (ISO)
deoxynivalenol  (ISO)
desferrioxamine B  (ISO)
dexamethasone  (EXP,ISO)
dextran sulfate  (ISO)
Di-n-octyl phthalate  (ISO)
diallyl disulfide  (ISO)
Diallyl sulfide  (ISO)
diallyl trisulfide  (ISO)
Diallyltetrasulfane  (ISO)
diarsenic trioxide  (EXP,ISO)
diazinon  (EXP,ISO)
dibenzofuran  (ISO)
dibutyl phthalate  (ISO)
Didecyldimethylammonium  (ISO)
dieldrin  (EXP)
diethyl maleate  (ISO)
diisononyl phthalate  (ISO)
dimethyl fumarate  (ISO)
dinitrogen  (ISO)
dioxygen  (EXP,ISO)
dipotassium bis[mu-tartrato(4-)]diantimonate(2-) trihydrate  (ISO)
diquat  (ISO)
disodium selenite  (EXP,ISO)
disulfiram  (ISO)
diuron  (EXP,ISO)
Doramectin  (EXP,ISO)
dorsomorphin  (EXP,ISO)
doxorubicin  (EXP,ISO)
elemental selenium  (EXP)
embelin  (ISO)
endosulfan  (EXP)
Enterolactone  (ISO)
epichlorohydrin  (ISO)
erlotinib hydrochloride  (ISO)
ethanol  (EXP,ISO)
ethyl methanesulfonate  (ISO)
eugenol  (ISO)
excitatory amino acid agonist  (EXP)
fenofibrate  (EXP,ISO)
fenthion  (ISO)
fenvalerate  (EXP)
ferrostatin-1  (EXP)
fingolimod hydrochloride  (ISO)
flavokawain B  (ISO)
flufenoxuron  (ISO)
fluoxetine  (ISO)
flutamide  (EXP)
folic acid  (ISO)
formaldehyde  (ISO)
FR900359  (ISO)
fructose  (EXP)
fumonisin B1  (ISO)
furosemide  (EXP)
Fusaric acid  (ISO)
gadolinium atom  (ISO)
gadolinium trichloride  (ISO)
galactose  (EXP,ISO)
gamma-hexachlorocyclohexane  (ISO)
gefitinib  (ISO)
Genipin  (ISO)
genistein  (ISO)
gentamycin  (EXP)
geraniol  (ISO)
ginsenoside Rb1  (ISO)
ginsenoside Rg2  (ISO)
glucose  (EXP,ISO)
glutathione  (ISO)
glycerol 2-phosphate  (ISO)
glycidol  (EXP)
glycochenodeoxycholic acid  (ISO)
glycocholic acid  (ISO)
glycodeoxycholic acid  (ISO)
glycyrrhizinic acid  (EXP)
gossypetin  (ISO)
graphene oxide  (ISO)
graphite  (EXP,ISO)
GW 4064  (ISO)
hexadecanoic acid  (EXP,ISO)
hexamethylene diisocyanate  (ISO)
Honokiol  (ISO)
HU-308  (ISO)
hydrogen peroxide  (EXP,ISO)
hydrogen sulfide  (ISO)
hydroquinone  (ISO)
hydroxychloroquine  (ISO)
hypochlorous acid  (ISO)
ifosfamide  (ISO)
indometacin  (ISO)
inositol  (EXP)
iodixanol  (EXP)
iohexol  (EXP)
iron atom  (ISO)
iron(0)  (ISO)
iron(III) citrate  (ISO)
isoflavones  (ISO)
isoprenaline  (ISO)
ivermectin  (ISO)
kainic acid  (EXP)
ketamine  (ISO)
L-ascorbic acid  (ISO)
L-ascorbic acid 2-phosphate  (ISO)
L-leucine  (ISO)
lactulose  (EXP,ISO)
lead diacetate  (EXP,ISO)
lead nitrate  (EXP,ISO)
lead(0)  (EXP,ISO)
leflunomide  (EXP,ISO)
lipopolysaccharide  (EXP,ISO)
liquiritigenin  (EXP)
liquiritin  (EXP)
lithium chloride  (ISO)
LY294002  (ISO)
lycopene  (ISO)
Maduramicin  (EXP)
manganese atom  (ISO)
manganese(0)  (ISO)
manganese(II) chloride  (EXP,ISO)
melatonin  (EXP,ISO)
melibiose  (ISO)
menadione  (ISO)
mercury dibromide  (ISO)
mesalamine  (EXP)
metformin  (EXP,ISO)
methamphetamine  (EXP,ISO)
methidathion  (ISO)
methotrexate  (ISO)
methoxyacetic acid  (EXP)
methyl methanesulfonate  (ISO)
methylisothiazolinone  (ISO)
methylmercury chloride  (EXP,ISO)
methylmercury(1+)  (EXP)
metronidazole  (ISO)
miconazole  (ISO)
microcystin-LR  (ISO)
mifepristone  (ISO)
mirtazapine  (EXP,ISO)
mitoxantrone  (ISO)
Monobutylphthalate  (EXP)
monocrotaline  (EXP)
morusin  (ISO)
N,N-diethyl-m-toluamide  (EXP)
N-(1,3-benzodioxol-5-ylmethyl)-2,6-dichlorobenzamide  (EXP)
N-acetyl-L-cysteine  (EXP,ISO)
N-benzyloxycarbonyl-L-leucyl-L-leucyl-L-leucinal  (ISO)
N-methyl-4-phenylpyridinium  (EXP,ISO)
N-methylformamide  (ISO)
N-methylnicotinate  (ISO)
N-nitrosodiethylamine  (EXP,ISO)
NADP zwitterion  (EXP)
NADP(+)  (EXP)
nefazodone  (EXP,ISO)
neomycin  (ISO)
nickel atom  (ISO)
nickel dichloride  (EXP,ISO)
nicotinamide  (ISO)
nicotine  (ISO)
nimesulide  (EXP)
NMN zwitterion  (ISO)
Nonidet P-40  (ISO)
notoginsenoside R1  (ISO)
obeticholic acid  (ISO)
ochratoxin A  (ISO)
octadecanoic acid  (ISO)
octreotide  (ISO)
olaparib  (EXP)
oleanolic acid  (ISO)
oleic acid  (ISO)
oligomycin A  (ISO)
organoselenium compound  (ISO)
osimertinib  (ISO)
oxaliplatin  (EXP)
oxidopamine  (EXP,ISO)
ozone  (ISO)
p-chloromercuribenzoic acid  (ISO)
p-cresol  (ISO)
Paeonol  (EXP)
paracetamol  (EXP,ISO)
paraformaldehyde macromolecule  (ISO)
paraquat  (EXP,ISO)
patulin  (ISO)
PCB138  (EXP)
pectolinarigenin  (ISO)
pentachlorophenol  (ISO)
pepstatin A  (ISO)
perfluorooctane-1-sulfonic acid  (EXP,ISO)
perfluorooctanoic acid  (ISO)
perfluoroundecanoic acid  (EXP)
permethrin  (EXP)
phenobarbital  (EXP,ISO)
phenol  (ISO)
phenylephrine  (EXP)
phenylmercury acetate  (ISO)
PhIP  (EXP)
phorbol 13-acetate 12-myristate  (ISO)
pirinixic acid  (ISO)
piroxicam  (ISO)
Plantamajoside  (ISO)
plumbagin  (ISO)
potassium bromate  (ISO)
potassium chromate  (ISO)
potassium dichromate  (ISO)
potassium iodide  (ISO)
pregnenolone 16alpha-carbonitrile  (EXP)
prodigiosin  (ISO)
progesterone  (ISO)
promethazine  (ISO)
pterostilbene  (ISO)
puerarin  (EXP)
Pyridostigmine bromide  (EXP)
pyrovalerone  (ISO)
quercetin  (EXP,ISO)
quinolinic acid  (EXP)
rac-1-monopalmitoylglycerol  (ISO)
rac-lactic acid  (ISO)
radon atom  (ISO)
radon(0)  (ISO)
raloxifene  (EXP,ISO)
reserpine  (ISO)
resveratrol  (EXP,ISO)
retinyl acetate  (ISO)
Rhein  (ISO)
rifampicin  (ISO)
Riluzole  (ISO)
Ro 31-8220  (ISO)
rotenone  (EXP,ISO)
S-(1,2-dichlorovinyl)-L-cysteine  (ISO)
salubrinal  (ISO)
SB 203580  (EXP,ISO)
SB 431542  (ISO)
SB-239063  (EXP)
SCH772984  (ISO)
Securinine  (ISO)
selenium atom  (EXP)
sepantronium  (ISO)
sertraline  (ISO)
sevoflurane  (EXP,ISO)
silicon dioxide  (ISO)
silver atom  (ISO)
silver(0)  (ISO)
simvastatin  (ISO)
sirolimus  (EXP,ISO)
sirtinol  (EXP)
SKF-96365 hydrochloride  (EXP)
sodium arsenate  (ISO)
sodium arsenite  (EXP,ISO)
sodium dichromate  (EXP,ISO)
sodium fluoride  (EXP,ISO)
Soman  (EXP)
sorafenib  (ISO)
sphingosine 1-phosphate  (EXP)
stilbenoid  (ISO)
streptozocin  (EXP,ISO)
succimer  (ISO)
sulforaphane  (ISO)
sulindac  (ISO)
sulindac sulfide  (ISO)
sunitinib  (ISO)
swainsonine  (EXP,ISO)
syringic acid  (ISO)
syringin  (ISO)
T-2 toxin  (ISO)
tamoxifen  (ISO)
taurine  (EXP,ISO)
taurocholic acid  (ISO)
Temsirolimus  (ISO)
tert-butyl hydroperoxide  (ISO)
testosterone enanthate  (ISO)
tetrachloromethane  (EXP,ISO)
Theaflavin 3,3'-digallate  (ISO)
thiamine(1+) chloride  (EXP,ISO)
thioacetamide  (EXP)
thiram  (ISO)
thymol  (ISO)
thymol sulfate(1-)  (ISO)
titanium dioxide  (ISO)
toosendanin  (ISO)
topotecan  (EXP)
trametinib  (ISO)
trans-piceid  (ISO)
triacsin C  (ISO)
tributylstannane  (ISO)
tricalcium bis(phosphate)  (ISO)
trichloroethene  (EXP,ISO)
triclosan  (ISO)
trimethyltin  (EXP)
troglitazone  (ISO)
Tungsten carbide  (ISO)
tunicamycin  (ISO)
tyloxapol  (ISO)
urethane  (ISO)
usnic acid  (ISO)
valproic acid  (ISO)
valsartan  (EXP)
vancomycin  (ISO)
venetoclax  (ISO)
venlafaxine hydrochloride  (EXP)
vincristine  (ISO)
vismodegib  (ISO)
vitamin D  (ISO)
wortmannin  (ISO)
XAV939  (ISO)
zearalenone  (EXP,ISO)
zidovudine  (EXP)
zinc atom  (ISO)
zinc oxide  (ISO)
zinc pyrithione  (ISO)
zinc(0)  (ISO)

Gene Ontology Annotations     Click to see Annotation Detail View

Cellular Component

References

References - curated
# Reference Title Reference Citation
1. Trehalose delays the progression of amyotrophic lateral sclerosis by enhancing autophagy in motoneurons. Castillo K, etal., Autophagy. 2013 Sep;9(9):1308-20. doi: 10.4161/auto.25188. Epub 2013 Jun 6.
2. ZIP3, a new splice variant of the PKC-zeta-interacting protein family, binds to GABAC receptors, PKC-zeta, and Kv beta 2. Croci C, etal., J Biol Chem 2003 Feb 21;278(8):6128-35.
3. The three 'P's of mitophagy: PARKIN, PINK1, and post-translational modifications. Durcan TM and Fon EA, Genes Dev. 2015 May 15;29(10):989-99. doi: 10.1101/gad.262758.115.
4. Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium. Gaudet P, etal., Brief Bioinform. 2011 Sep;12(5):449-62. doi: 10.1093/bib/bbr042. Epub 2011 Aug 27.
5. Differential stimulation of PKC phosphorylation of potassium channels by ZIP1 and ZIP2. Gong J, etal., Science. 1999 Sep 3;285(5433):1565-9.
6. The Nrf2 regulatory network provides an interface between redox and intermediary metabolism. Hayes JD and Dinkova-Kostova AT, Trends Biochem Sci. 2014 Apr;39(4):199-218. doi: 10.1016/j.tibs.2014.02.002. Epub 2014 Mar 16.
7. Angiotensin-(1-7) inhibits autophagy in the brain of spontaneously hypertensive rats. Jiang T, etal., Pharmacol Res. 2013 May;71:61-8. doi: 10.1016/j.phrs.2013.03.001. Epub 2013 Mar 15.
8. Axonal protection by Nmnat3 overexpression with involvement of autophagy in optic nerve degeneration. Kitaoka Y, etal., Cell Death Dis. 2013 Oct 17;4:e860. doi: 10.1038/cddis.2013.391.
9. Mitochondria and mitophagy: the yin and yang of cell death control. Kubli DA and Gustafsson AB, Circ Res. 2012 Oct 12;111(9):1208-21. doi: 10.1161/CIRCRESAHA.112.265819.
10. Recurrent mutation of the gene encoding sequestosome 1 (SQSTM1/p62) in Paget disease of bone. Laurin N, etal., Am J Hum Genet. 2002 Jun;70(6):1582-8. Epub 2002 Apr 30.
11. Acute hyperglycemia together with hematoma of high-glucose blood exacerbates neurological injury in a rat model of intracerebral hemorrhage. Liu RY, etal., Neurosci Bull. 2014 Feb;30(1):90-8. doi: 10.1007/s12264-013-1371-6. Epub 2013 Jul 25.
12. Rat ISS GO annotations from MGI mouse gene data--August 2006 MGD data from the GO Consortium
13. Transcriptional activation of p62/A170/ZIP during the formation of the aggregates: possible mechanisms and the role in Lewy body formation in Parkinson's disease. Nakaso K, etal., Brain Res. 2004 Jun 25;1012(1-2):42-51.
14. Electronic Transfer of LocusLink and RefSeq Data NCBI rat LocusLink and RefSeq merged data July 26, 2002
15. OMIM Disease Annotation Pipeline OMIM Disease Annotation Pipeline
16. PID Annotation Import Pipeline Pipeline to import Pathway Interaction Database annotations from NCI into RGD
17. Interaction of protein kinase C zeta with ZIP, a novel protein kinase C-binding protein. Puls A, etal., Proc Natl Acad Sci U S A 1997 Jun 10;94(12):6191-6.
18. ClinVar Automated Import and Annotation Pipeline RGD automated import pipeline for ClinVar variants, variant-to-disease annotations and gene-to-disease annotations
19. Data Import for Chemical-Gene Interactions RGD automated import pipeline for gene-chemical interactions
20. Comprehensive gene review and curation RGD comprehensive gene curation
21. Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences. Strausberg RL, etal., Proc Natl Acad Sci U S A. 2002 Dec 24;99(26):16899-903. Epub 2002 Dec 11.
22. Rat pachytene spermatocytes down-regulate a polo-like kinase and up-regulate a thiol-specific antioxidant protein, whereas sertoli cells down-regulate a phosphodiesterase and up-regulate an oxidative stress protein after exposure to methoxyethanol and methoxyacetic acid. Syed V and Hecht NB, Endocrinology 1998 Aug;139(8):3503-11.
23. Tentative Sequence Identification Numbers Tentative Sequence Data IDs. TIGR Gene Index, Rat Data
24. Regulation of endoplasmic reticulum stress in rat cortex by p62/ZIP through the Keap1-Nrf2-ARE signalling pathway after transient focal cerebral ischaemia. Wang W, etal., Brain Inj. 2013;27(7-8):924-33. doi: 10.3109/02699052.2013.793397. Epub 2013 Jun 19.
Additional References at PubMed
PMID:8650207   PMID:10366737   PMID:11162503   PMID:11244088   PMID:11500922   PMID:11981755   PMID:12857745   PMID:14676191   PMID:15143057   PMID:15489334   PMID:15802564   PMID:16079148  
PMID:16169070   PMID:16246731   PMID:16252010   PMID:17580304   PMID:17699685   PMID:18174161   PMID:18374665   PMID:19004011   PMID:19056867   PMID:19182904   PMID:19640926   PMID:20168092  
PMID:20173742   PMID:20357094   PMID:20421418   PMID:20452972   PMID:20457763   PMID:20562859   PMID:20814419   PMID:20979579   PMID:21173155   PMID:21220506   PMID:21455601   PMID:21536669  
PMID:21707618   PMID:21900206   PMID:22033522   PMID:22622177   PMID:22761437   PMID:22792322   PMID:22948227   PMID:23148214   PMID:24035364   PMID:24713655   PMID:24954904   PMID:24959866  
PMID:25127057   PMID:25150927   PMID:25416956   PMID:25686248   PMID:25708205   PMID:25761618   PMID:26199377   PMID:26284655   PMID:26364802   PMID:27368102   PMID:27564518   PMID:27631370  
PMID:28076378   PMID:28404643   PMID:28655770   PMID:29057768   PMID:29554128   PMID:30273743   PMID:30744518   PMID:34581931   PMID:37466855   PMID:38308640  


Genomics

Comparative Map Data
Sqstm1
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr81035,026,598 - 35,037,750 (-)NCBIGRCr8
mRatBN7.21034,525,517 - 34,536,670 (-)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl1034,525,519 - 34,536,673 (-)EnsemblmRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx1039,200,880 - 39,212,041 (-)NCBIRnor_SHRUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.0107,740,133 - 7,751,294 (-)NCBIRnor_SHRSPUTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.01034,194,553 - 34,205,714 (-)NCBIRnor_WKYUTH_Rnor_WKY_Bbb_1.0
Rnor_6.01035,704,728 - 35,716,316 (-)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl1035,704,730 - 35,716,294 (-)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.01035,463,172 - 35,474,754 (-)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.41035,751,300 - 35,762,630 (-)NCBIRGSC3.4RGSC_v3.4rn4RGSC3.4
RGSC_v3.11035,752,706 - 35,763,676 (-)NCBI
Celera1033,874,680 - 33,885,832 (-)NCBICelera
Cytogenetic Map10q22NCBI
SQSTM1
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh385179,806,393 - 179,838,078 (+)NCBIGRCh38GRCh38hg38GRCh38
GRCh38.p14 Ensembl5179,806,398 - 179,838,078 (+)EnsemblGRCh38hg38GRCh38
GRCh375179,233,393 - 179,265,078 (+)NCBIGRCh37GRCh37hg19GRCh37
Build 365179,180,503 - 179,197,684 (+)NCBINCBI36Build 36hg18NCBI36
Build 345179,180,502 - 179,197,681NCBI
Celera5174,858,545 - 174,890,234 (+)NCBICelera
Cytogenetic Map5q35.3NCBI
HuRef5173,959,564 - 173,990,246 (+)NCBIHuRef
CHM1_15178,665,789 - 178,697,494 (+)NCBICHM1_1
T2T-CHM13v2.05180,361,589 - 180,393,289 (+)NCBIT2T-CHM13v2.0
Sqstm1
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm391150,090,979 - 50,105,303 (-)NCBIGRCm39GRCm39mm39
GRCm39 Ensembl1150,090,193 - 50,101,654 (-)EnsemblGRCm39 Ensembl
GRCm381150,200,152 - 50,210,820 (-)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 E