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Gene: Git1 (GIT ArfGAP 1) Rattus norvegicus
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Symbol: Git1
Name: GIT ArfGAP 1
Description: Exhibits GTPase activator activity; protein homodimerization activity; and small GTPase binding activity. Involved in several processes, including cellular response to epidermal growth factor stimulus; dendritic spine development; and regulation of signal transduction. Localizes to several cellular components, including the GABA-ergic synapse; cytoplasm; and glutamatergic synapse. Human ortholog(s) of this gene implicated in attention deficit hyperactivity disorder. Orthologous to human GIT1 (GIT ArfGAP 1); PARTICIPATES IN Arf family mediated signaling pathway; E-cadherin signaling pathway; endocytosis pathway; INTERACTS WITH 2,4-dinitrotoluene; ammonium chloride; bisphenol A.
Type: protein-coding
RefSeq Status: PROVISIONAL
Also known as: ARF GAP GIT1; ARF GTPase-activating protein GIT1; CAT-1; CAT1; cool-associated and tyrosine-phosphorylated protein 1; G protein-coupled receptor kinase interacting ArfGAP 1; G protein-coupled receptor kinase interactor 1; G protein-coupled receptor kinase-associated ADP ribosylation factor GTPase-activating protein (GIT1); G protein-coupled receptor kinase-interactor 1; GRK-interacting protein 1
Orthologs:
Homo sapiens (human) : GIT1 (GIT ArfGAP 1)  HGNC  Alliance
Mus musculus (house mouse) : Git1 (GIT ArfGAP 1)  MGI  Alliance
Chinchilla lanigera (long-tailed chinchilla) : Git1 (GIT ArfGAP 1)
Pan paniscus (bonobo/pygmy chimpanzee) : GIT1 (GIT ArfGAP 1)
Canis lupus familiaris (dog) : GIT1 (GIT ArfGAP 1)
Ictidomys tridecemlineatus (thirteen-lined ground squirrel) : Git1 (GIT ArfGAP 1)
Sus scrofa (pig) : GIT1 (GIT ArfGAP 1)
more info ...
Latest Assembly: Rnor_6.0 - RGSC Genome Assembly v6.0
NCBI Annotation Information: Annotation category: partial on reference assembly
Position:
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Rnor_6.01062,656,000 - 62,664,467 (-)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_5.01062,352,883 - 62,362,201 (-)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.41066,610,282 - 66,618,919 (-)NCBIRGSC3.4rn4RGSC3.4
RGSC_v3.11066,623,904 - 66,632,546 (-)NCBI
Celera1061,351,008 - 61,359,475 (+)NCBICelera
Cytogenetic Map10q24NCBI
JBrowse: View Region in Genome Browser (JBrowse)
Model


Disease Annotations
Gene-Chemical Interaction Annotations
Gene Ontology Annotations
Molecular Pathway Annotations
References - curated
References - uncurated

Genomics

Comparative Map Data
Position Markers
QTLs in Region (Rnor_6.0)
miRNA Target Status

Sequence

Nucleotide Sequences
Protein Sequences
Transcriptome
Promoters

Strain Variation

Strain Sequence Variants (Rnor 5.0)

Additional Information

External Database Links
Nomenclature History
RGD Curation Notes
 
More on Git1
Alliance Gene
NCBI Gene
Ensembl Gene
JBrowse: rn5 rn6
NCBI Genome Data Viewer

RGD Object Information
RGD ID: 69331
Created: 2001-11-14
Species: Rattus norvegicus
Last Modified: 2019-08-20
Status: ACTIVE



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RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.