Git1 (GIT ArfGAP 1) - Rat Genome Database

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Gene: Git1 (GIT ArfGAP 1) Chinchilla lanigera
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Symbol: Git1
Name: GIT ArfGAP 1
RGD ID: 8816544
Description: ENCODES a protein that exhibits gamma-tubulin binding (ortholog); GTPase activator activity (ortholog); identical protein binding (ortholog); INVOLVED IN brain development (ortholog); cell redox homeostasis (ortholog); cellular response to epidermal growth factor stimulus (ortholog); PARTICIPATES IN Arf family mediated signaling pathway; E-cadherin signaling pathway; ASSOCIATED WITH attention deficit hyperactivity disorder (ortholog); Developmental Disease (ortholog); genetic disease (ortholog); FOUND IN calyx of Held (ortholog); centrosome (ortholog); cytosol (ortholog)
Type: protein-coding
RefSeq Status: MODEL
Previously known as: ARF GTPase-activating protein GIT1; G protein-coupled receptor kinase interacting ArfGAP 1
RGD Orthologs
Human
Mouse
Rat
Bonobo
Dog
Squirrel
Pig
Green Monkey
Naked Mole-Rat
Alliance Orthologs
More Info more info ...
Latest Assembly: ChiLan1.0 - Chinchilla ChiLan1.0 Assembly
NCBI Annotation Information: Annotation category: partial on reference assembly
Position:
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0 EnsemblNW_0049554813,670,111 - 3,685,051 (+)EnsemblChiLan1.0
ChiLan1.0NW_0049554813,671,728 - 3,681,279 (+)NCBIChiLan1.0ChiLan1.0
JBrowse: View Region in Genome Browser (JBrowse)
Model


Gene Ontology Annotations     Click to see Annotation Detail View

Cellular Component

Molecular Pathway Annotations     Click to see Annotation Detail View
References

References - curated
# Reference Title Reference Citation
1. Transitive Annotation Pipeline Automated assignment of GO, PW and RDO ISO annotations across species
Additional References at PubMed
PMID:22301074   PMID:30032202  


Genomics

Comparative Map Data
Git1
(Chinchilla lanigera - long-tailed chinchilla)
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0 EnsemblNW_0049554813,670,111 - 3,685,051 (+)EnsemblChiLan1.0
ChiLan1.0NW_0049554813,671,728 - 3,681,279 (+)NCBIChiLan1.0ChiLan1.0
GIT1
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh381729,573,475 - 29,589,648 (-)NCBIGRCh38GRCh38hg38GRCh38
GRCh38.p14 Ensembl1729,573,475 - 29,594,054 (-)EnsemblGRCh38hg38GRCh38
GRCh371727,900,493 - 27,916,666 (-)NCBIGRCh37GRCh37hg19GRCh37
Build 361724,924,613 - 24,940,736 (-)NCBINCBI36Build 36hg18NCBI36
Build 341724,924,619 - 24,940,735NCBI
Celera1724,761,352 - 24,777,476 (-)NCBICelera
Cytogenetic Map17q11.2NCBI
HuRef1724,109,826 - 24,125,786 (-)NCBIHuRef
CHM1_11727,963,149 - 27,983,295 (-)NCBICHM1_1
T2T-CHM13v2.01730,516,351 - 30,532,526 (-)NCBIT2T-CHM13v2.0
Git1
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm391177,384,114 - 77,398,600 (+)NCBIGRCm39GRCm39mm39
GRCm39 Ensembl1177,384,388 - 77,398,612 (+)EnsemblGRCm39 Ensembl
GRCm381177,493,288 - 77,507,774 (+)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl1177,493,562 - 77,507,786 (+)EnsemblGRCm38mm10GRCm38
MGSCv371177,306,914 - 77,321,276 (+)NCBIGRCm37MGSCv37mm9NCBIm37
MGSCv361177,309,607 - 77,323,969 (+)NCBIMGSCv36mm8
Celera1184,991,973 - 85,006,335 (+)NCBICelera
Cytogenetic Map11B5NCBI
cM Map1146.61NCBI
Git1
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr81062,840,165 - 62,854,508 (+)NCBIGRCr8
mRatBN7.21062,342,082 - 62,356,379 (+)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl1062,342,299 - 62,356,373 (+)EnsemblmRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx1066,992,057 - 67,006,179 (+)NCBIRnor_SHRUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.01066,497,543 - 66,511,665 (+)NCBIRnor_SHRSPUTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.01061,970,798 - 61,984,917 (+)NCBIRnor_WKYUTH_Rnor_WKY_Bbb_1.0
Rnor_6.01062,656,000 - 62,664,467 (-)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl1062,656,000 - 62,664,466 (-)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.01062,352,883 - 62,362,201 (-)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.41066,610,282 - 66,618,919 (-)NCBIRGSC3.4RGSC_v3.4rn4RGSC3.4
RGSC_v3.11066,623,904 - 66,632,546 (-)NCBI
Celera1061,351,008 - 61,359,475 (+)NCBICelera
Cytogenetic Map10q24NCBI
GIT1
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
NHGRI_mPanPan1-v21934,866,807 - 34,882,933 (+)NCBINHGRI_mPanPan1-v2
NHGRI_mPanPan11736,748,981 - 36,765,176 (+)NCBINHGRI_mPanPan1
Mhudiblu_PPA_v01727,185,025 - 27,201,146 (+)NCBIMhudiblu_PPA_v0Mhudiblu_PPA_v0panPan3
PanPan1.11727,707,452 - 27,717,857 (+)NCBIpanpan1.1PanPan1.1panPan2
PanPan1.1 Ensembl1727,706,776 - 27,717,857 (+)Ensemblpanpan1.1panPan2
GIT1
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.1943,676,707 - 43,686,566 (-)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
CanFam3.1 Ensembl943,677,899 - 43,693,177 (-)EnsemblCanFam3.1canFam3CanFam3.1
Dog10K_Boxer_Tasha942,829,811 - 42,846,296 (-)NCBIDog10K_Boxer_Tasha
ROS_Cfam_1.0944,492,902 - 44,509,385 (-)NCBIROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl944,492,901 - 44,508,582 (-)EnsemblROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.1943,277,271 - 43,293,743 (-)NCBIUMICH_Zoey_3.1
UNSW_CanFamBas_1.0943,567,974 - 43,584,445 (-)NCBIUNSW_CanFamBas_1.0
UU_Cfam_GSD_1.0943,648,051 - 43,664,538 (-)NCBIUU_Cfam_GSD_1.0
Git1
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HiC_Itri_2NW_02440560242,806,717 - 42,827,559 (-)NCBIHiC_Itri_2
SpeTri2.0 EnsemblNW_0049365385,684,644 - 5,695,043 (-)EnsemblSpeTri2.0SpeTri2.0 Ensembl
SpeTri2.0NW_0049365385,684,660 - 5,694,779 (-)NCBISpeTri2.0SpeTri2.0SpeTri2.0
GIT1
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 Ensembl1245,768,176 - 45,783,658 (-)EnsemblSscrofa11.1susScr11Sscrofa11.1
Sscrofa11.11245,768,172 - 45,783,652 (-)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
Sscrofa10.21247,719,221 - 47,730,533 (-)NCBISscrofa10.2Sscrofa10.2susScr3
GIT1
(Chlorocebus sabaeus - green monkey)
Green Monkey AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.11623,313,629 - 23,329,665 (-)NCBIChlSab1.1ChlSab1.1chlSab2
ChlSab1.1 Ensembl1623,315,439 - 23,329,469 (-)EnsemblChlSab1.1ChlSab1.1 EnsemblchlSab2
Vero_WHO_p1.0NW_0236660756,742,731 - 6,758,827 (+)NCBIVero_WHO_p1.0Vero_WHO_p1.0
Git1
(Heterocephalus glaber - naked mole-rat)
Naked Mole-Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla_female_1.0 EnsemblNW_0046247862,071,382 - 2,086,910 (-)EnsemblHetGla_female_1.0HetGla_female_1.0 EnsemblhetGla2
HetGla 1.0NW_0046247862,071,376 - 2,086,929 (-)NCBIHetGla_female_1.0HetGla 1.0hetGla2


Expression


Sequence


Ensembl Acc Id: ENSCLAT00000007677   ⟹   ENSCLAP00000007560
Type: CODING
Position:
Chinchilla AssemblyChrPosition (strand)Source
ChiLan1.0 EnsemblNW_0049554813,670,111 - 3,685,051 (+)Ensembl
Ensembl Acc Id: ENSCLAT00000007678   ⟹   ENSCLAP00000007561
Type: CODING
Position:
Chinchilla AssemblyChrPosition (strand)Source
ChiLan1.0 EnsemblNW_0049554813,670,111 - 3,681,279 (+)Ensembl
RefSeq Acc Id: XM_005402676   ⟹   XP_005402733
Type: CODING
Position:
Chinchilla AssemblyChrPosition (strand)Source
ChiLan1.0NW_0049554813,671,728 - 3,681,279 (+)NCBI
Sequence:
Protein Sequences
Protein RefSeqs XP_005402733 (Get FASTA)   NCBI Sequence Viewer  
Ensembl Protein ENSCLAP00000007560.1
  ENSCLAP00000007561
  ENSCLAP00000007561.1
RefSeq Acc Id: XP_005402733   ⟸   XM_005402676
- UniProtKB: A0A8C2UZ80 (UniProtKB/TrEMBL)
- Sequence:
Ensembl Acc Id: ENSCLAP00000007560   ⟸   ENSCLAT00000007677
Ensembl Acc Id: ENSCLAP00000007561   ⟸   ENSCLAT00000007678
Protein Domains
Arf-GAP


Additional Information

Database Acc Id Source(s)
Ensembl Genes ENSCLAG00000005307 Ensembl, ENTREZGENE, UniProtKB/TrEMBL
Ensembl Transcript ENSCLAT00000007677.1 UniProtKB/TrEMBL
  ENSCLAT00000007678 ENTREZGENE
  ENSCLAT00000007678.1 UniProtKB/TrEMBL
Gene3D-CATH 1.10.220.150 UniProtKB/TrEMBL
  1.20.5.170 UniProtKB/TrEMBL
  1.25.40.20 UniProtKB/TrEMBL
  Nucleotidyltransferases domain 2 UniProtKB/TrEMBL
InterPro Ankyrin_rpt UniProtKB/TrEMBL
  Ankyrin_rpt-contain_sf UniProtKB/TrEMBL
  ARFGAP/RecO UniProtKB/TrEMBL
  ArfGAP_dom UniProtKB/TrEMBL
  ArfGAP_dom_sf UniProtKB/TrEMBL
  GIT-like UniProtKB/TrEMBL
  GIT1/2_CC UniProtKB/TrEMBL
  GIT1_C UniProtKB/TrEMBL
  GIT_SHD UniProtKB/TrEMBL
NCBI Gene Git1 ENTREZGENE
PANTHER ARF GTPASE-ACTIVATING PROTEIN GIT1 UniProtKB/TrEMBL
  G PROTEIN-COUPLED RECEPTOR KINASE INTERACTING ARFGAP UniProtKB/TrEMBL
Pfam Ank_2 UniProtKB/TrEMBL
  ArfGap UniProtKB/TrEMBL
  GIT1_C UniProtKB/TrEMBL
  GIT_CC UniProtKB/TrEMBL
  GIT_SHD UniProtKB/TrEMBL
PROSITE ANK_REP_REGION UniProtKB/TrEMBL
  ANK_REPEAT UniProtKB/TrEMBL
  ARFGAP UniProtKB/TrEMBL
SMART ANK UniProtKB/TrEMBL
  ArfGap UniProtKB/TrEMBL
  GIT UniProtKB/TrEMBL
Superfamily-SCOP SSF48403 UniProtKB/TrEMBL
  SSF57863 UniProtKB/TrEMBL
UniProt A0A8C2UZ80 ENTREZGENE, UniProtKB/TrEMBL
  A0A8C2YLJ8_CHILA UniProtKB/TrEMBL


Nomenclature History
Date Current Symbol Current Name Previous Symbol Previous Name Description Reference Status
2016-08-03 Git1  GIT ArfGAP 1    G protein-coupled receptor kinase interacting ArfGAP 1  Symbol and/or name change 5135510 APPROVED