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Gene: Nek8 (NIMA-related kinase 8) Rattus norvegicus
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Symbol: Nek8
Name: NIMA-related kinase 8
Description: Predicted to have protein serine/threonine kinase activity. Predicted to be involved in several processes, including animal organ development; cilium assembly; and regulation of hippo signaling. Predicted to localize to the ciliary base and ciliary inversin compartment. Human ortholog(s) of this gene implicated in nephronophthisis 9 and renal-hepatic-pancreatic dysplasia. Orthologous to human NEK8 (NIMA related kinase 8); INTERACTS WITH 2,6-dinitrotoluene; 4-amino-2,6-dinitrotoluene; bisphenol A.
Type: protein-coding
RefSeq Status: PROVISIONAL
Also known as: LOC287473; never in mitosis A-related kinase 8; NIMA (never in mitosis gene a)- related kinase 8; NIMA (never in mitosis gene a)-related expressed kinase 8; nimA-related protein kinase 8; serine/threonine-protein kinase Nek8
Orthologs:
Homo sapiens (human) : NEK8 (NIMA related kinase 8)  HGNC  Alliance
Mus musculus (house mouse) : Nek8 (NIMA (never in mitosis gene a)-related expressed kinase 8)  MGI  Alliance
Chinchilla lanigera (long-tailed chinchilla) : Nek8 (NIMA related kinase 8)
Pan paniscus (bonobo/pygmy chimpanzee) : NEK8 (NIMA related kinase 8)
Canis lupus familiaris (dog) : NEK8 (NIMA related kinase 8)
Ictidomys tridecemlineatus (thirteen-lined ground squirrel) : Nek8 (NIMA related kinase 8)
Sus scrofa (pig) : NEK8 (NIMA related kinase 8)
more info ...
Latest Assembly: Rnor_6.0 - RGSC Genome Assembly v6.0
Position:
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Rnor_6.01065,404,489 - 65,439,059 (-)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_5.01066,196,993 - 66,230,588 (+)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.41064,458,886 - 64,470,044 (+)NCBIRGSC3.4rn4RGSC3.4
RGSC_v3.11064,472,568 - 64,483,018 (+)NCBI
Celera1062,038,910 - 62,050,078 (-)NCBICelera
Cytogenetic Map10q25NCBI
JBrowse: View Region in Genome Browser (JBrowse)
Model


References - curated
References - uncurated
RGD Disease Portals

Genomics

Comparative Map Data
Position Markers
QTLs in Region (Rnor_6.0)
miRNA Target Status

Sequence

Nucleotide Sequences
Protein Sequences
Transcriptome
Promoters

Strain Variation

Strain Sequence Variants (Rnor 5.0)
Damaging Variants

Additional Information

External Database Links
Nomenclature History
 
More on Nek8
Alliance Gene
NCBI Gene
Ensembl Gene
JBrowse: rn5 rn6
NCBI Genome Data Viewer

RGD Object Information
RGD ID: 1306897
Created: 2005-01-12
Species: Rattus norvegicus
Last Modified: 2019-04-23
Status: ACTIVE



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RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.