Ndel1 (nudE neurodevelopment protein 1-like 1) - Rat Genome Database

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Gene: Ndel1 (nudE neurodevelopment protein 1-like 1) Rattus norvegicus
Analyze
Symbol: Ndel1
Name: nudE neurodevelopment protein 1-like 1
RGD ID: 621235
Description: Enables oligopeptidase activity. Involved in neuron projection development; positive regulation of axon extension; and positive regulation of axon regeneration. Acts upstream of or within nuclear membrane disassembly. Located in several cellular components, including central region of growth cone; centrosome; and nuclear envelope. Part of kinesin complex. Orthologous to human NDEL1 (nudE neurodevelopment protein 1 like 1); INTERACTS WITH 2,3,7,8-tetrachlorodibenzodioxine; 6-propyl-2-thiouracil; ammonium chloride.
Type: protein-coding
RefSeq Status: PROVISIONAL
Previously known as: endooligopeptidase A; EOPA; LIS1-interacting protein NUDEL; nuclear distribution gene E-like homolog 1; nuclear distribution gene E-like homolog 1 (A. nidulans); nuclear distribution protein nudE-like 1; nudE nuclear distribution gene E homolog (A. nidulans)-like 1; nudE nuclear distribution gene E homolog like 1; nudE nuclear distribution gene E homolog like 1 (A. nidulans); nudE nuclear distribution gene E homolog-like 1; NUDE2; Nudel
RGD Orthologs
Human
Mouse
Chinchilla
Bonobo
Dog
Squirrel
Pig
Green Monkey
Naked Mole-Rat
Alliance Orthologs
More Info more info ...
Latest Assembly: mRatBN7.2 - mRatBN7.2 Assembly
Position:
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr81054,001,435 - 54,080,909 (-)NCBIGRCr8
mRatBN7.21053,505,628 - 53,582,025 (-)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl1053,516,491 - 53,570,907 (-)EnsemblmRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx1058,191,668 - 58,224,366 (-)NCBIRnor_SHRUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.01057,680,698 - 57,713,203 (-)NCBIRnor_SHRSPUTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.01053,189,257 - 53,222,150 (-)NCBIRnor_WKYUTH_Rnor_WKY_Bbb_1.0
Rnor_6.01055,398,919 - 55,456,654 (-)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl1055,411,901 - 55,444,861 (-)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.01055,140,094 - 55,198,600 (-)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.41055,581,250 - 55,614,926 (-)NCBIRGSC3.4RGSC_v3.4rn4RGSC3.4
RGSC_v3.11055,594,876 - 55,628,545 (-)NCBI
Celera1052,697,424 - 52,729,662 (-)NCBICelera
Cytogenetic Map10q24NCBI
JBrowse: View Region in Genome Browser (JBrowse)
Model


Disease Annotations     Click to see Annotation Detail View

Gene Ontology Annotations     Click to see Annotation Detail View

Cellular Component

Molecular Function

References

References - curated
# Reference Title Reference Citation
1. Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium. Gaudet P, etal., Brief Bioinform. 2011 Sep;12(5):449-62. doi: 10.1093/bib/bbr042. Epub 2011 Aug 27.
2. Rat ISS GO annotations from GOA human gene data--August 2006 GOA data from the GO Consortium
3. Inhibition of NUDEL (nuclear distribution element-like)-oligopeptidase activity by disrupted-in-schizophrenia 1. Hayashi MA, etal., Proc Natl Acad Sci U S A. 2005 Mar 8;102(10):3828-33. Epub 2005 Feb 23.
4. Lis1 and Ndel1 influence the timing of nuclear envelope breakdown in neural stem cells. Hebbar S, etal., J Cell Biol. 2008 Sep 22;182(6):1063-71. doi: 10.1083/jcb.200803071.
5. DISC1-NDEL1/NUDEL protein interaction, an essential component for neurite outgrowth, is modulated by genetic variations of DISC1. Kamiya A, etal., Hum Mol Genet. 2006 Nov 15;15(22):3313-23. Epub 2006 Oct 11.
6. Expression of DISC1 binding partners is reduced in schizophrenia and associated with DISC1 SNPs. Lipska BK, etal., Hum Mol Genet. 2006 Apr 15;15(8):1245-58. Epub 2006 Mar 1.
7. Rat ISS GO annotations from MGI mouse gene data--August 2006 MGD data from the GO Consortium
8. Electronic Transfer of LocusLink and RefSeq Data NCBI rat LocusLink and RefSeq merged data July 26, 2002
9. Data Import for Chemical-Gene Interactions RGD automated import pipeline for gene-chemical interactions
10. Information Derived from GenBank Report RGD, Sept. 2003
11. Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences. Strausberg RL, etal., Proc Natl Acad Sci U S A. 2002 Dec 24;99(26):16899-903. Epub 2002 Dec 11.
12. DISC1 regulates the transport of the NUDEL/LIS1/14-3-3epsilon complex through kinesin-1. Taya S, etal., J Neurosci. 2007 Jan 3;27(1):15-26.
13. Ndel1 promotes axon regeneration via intermediate filaments. Toth C, etal., PLoS ONE. 2008 Apr 23;3(4):e2014.
Additional References at PubMed
PMID:10931877   PMID:11163259   PMID:11163260   PMID:15208636   PMID:15489334   PMID:16107726   PMID:16203747   PMID:16641100   PMID:17060449   PMID:17600710   PMID:17825401   PMID:17997972  
PMID:18331715   PMID:18983980   PMID:19668197   PMID:20624590   PMID:21283621   PMID:21890215   PMID:22843697   PMID:23551859   PMID:25416956   PMID:27777970   PMID:28057765  


Genomics

Comparative Map Data
Ndel1
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr81054,001,435 - 54,080,909 (-)NCBIGRCr8
mRatBN7.21053,505,628 - 53,582,025 (-)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl1053,516,491 - 53,570,907 (-)EnsemblmRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx1058,191,668 - 58,224,366 (-)NCBIRnor_SHRUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.01057,680,698 - 57,713,203 (-)NCBIRnor_SHRSPUTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.01053,189,257 - 53,222,150 (-)NCBIRnor_WKYUTH_Rnor_WKY_Bbb_1.0
Rnor_6.01055,398,919 - 55,456,654 (-)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl1055,411,901 - 55,444,861 (-)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.01055,140,094 - 55,198,600 (-)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.41055,581,250 - 55,614,926 (-)NCBIRGSC3.4RGSC_v3.4rn4RGSC3.4
RGSC_v3.11055,594,876 - 55,628,545 (-)NCBI
Celera1052,697,424 - 52,729,662 (-)NCBICelera
Cytogenetic Map10q24NCBI
NDEL1
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh38178,413,131 - 8,474,328 (+)NCBIGRCh38GRCh38hg38GRCh38
GRCh38.p14 Ensembl178,413,131 - 8,490,411 (+)EnsemblGRCh38hg38GRCh38
GRCh37178,339,202 - 8,371,481 (+)NCBIGRCh37GRCh37hg19GRCh37
Build 36178,279,904 - 8,312,206 (+)NCBINCBI36Build 36hg18NCBI36
Build 34178,279,903 - 8,312,196NCBI
Celera178,370,018 - 8,402,309 (+)NCBICelera
Cytogenetic Map17p13.1NCBI
HuRef178,238,370 - 8,270,684 (+)NCBIHuRef
CHM1_1178,348,024 - 8,380,341 (+)NCBICHM1_1
T2T-CHM13v2.0178,319,371 - 8,379,912 (+)NCBIT2T-CHM13v2.0
Ndel1
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm391168,712,260 - 68,743,961 (-)NCBIGRCm39GRCm39mm39
GRCm39 Ensembl1168,712,260 - 68,762,684 (-)EnsemblGRCm39 Ensembl
GRCm381168,821,434 - 68,853,146 (-)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl1168,821,434 - 68,871,858 (-)EnsemblGRCm38mm10GRCm38
MGSCv371168,634,936 - 68,666,633 (-)NCBIGRCm37MGSCv37mm9NCBIm37
MGSCv361168,637,629 - 68,669,257 (-)NCBIMGSCv36mm8
Celera1175,766,319 - 75,797,740 (-)NCBICelera
Cytogenetic Map11B3NCBI
cM Map1142.09NCBI
Ndel1
(Chinchilla lanigera - long-tailed chinchilla)
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0 EnsemblNW_0049554678,432,806 - 8,468,155 (-)EnsemblChiLan1.0
ChiLan1.0NW_0049554678,432,806 - 8,486,563 (-)NCBIChiLan1.0ChiLan1.0
NDEL1
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
NHGRI_mPanPan1-v21965,280,844 - 65,313,183 (-)NCBINHGRI_mPanPan1-v2
NHGRI_mPanPan11770,090,295 - 70,122,627 (-)NCBINHGRI_mPanPan1
Mhudiblu_PPA_v01743,186,255 - 43,218,436 (-)NCBIMhudiblu_PPA_v0Mhudiblu_PPA_v0panPan3
PanPan1.11747,918,827 - 47,942,773 (-)NCBIpanpan1.1PanPan1.1panPan2
PanPan1.1 Ensembl1747,918,827 - 47,950,749 (-)Ensemblpanpan1.1panPan2
NDEL1
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.1533,187,614 - 33,244,483 (+)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
CanFam3.1 Ensembl533,204,452 - 33,266,052 (+)EnsemblCanFam3.1canFam3CanFam3.1
Dog10K_Boxer_Tasha533,323,255 - 33,402,505 (+)NCBIDog10K_Boxer_Tasha
ROS_Cfam_1.0533,290,630 - 33,369,996 (+)NCBIROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl533,307,740 - 33,375,499 (+)EnsemblROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.1533,257,900 - 33,337,132 (+)NCBIUMICH_Zoey_3.1
UNSW_CanFamBas_1.0533,213,196 - 33,292,473 (+)NCBIUNSW_CanFamBas_1.0
UU_Cfam_GSD_1.0533,393,012 - 33,472,138 (+)NCBIUU_Cfam_GSD_1.0
Ndel1
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HiC_Itri_2NW_02440560248,182,799 - 48,227,535 (+)NCBIHiC_Itri_2
SpeTri2.0 EnsemblNW_0049365951,656,956 - 1,689,322 (+)EnsemblSpeTri2.0SpeTri2.0 Ensembl
SpeTri2.0NW_0049365951,656,956 - 1,692,775 (+)NCBISpeTri2.0SpeTri2.0SpeTri2.0
NDEL1
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 Ensembl1253,557,175 - 53,640,457 (+)EnsemblSscrofa11.1susScr11Sscrofa11.1
Sscrofa11.11253,553,897 - 53,640,470 (+)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
Sscrofa10.21256,296,922 - 56,336,396 (+)NCBISscrofa10.2Sscrofa10.2susScr3
NDEL1
(Chlorocebus sabaeus - green monkey)
Green Monkey AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.1167,797,858 - 7,831,211 (+)NCBIChlSab1.1ChlSab1.1chlSab2
Vero_WHO_p1.0NW_02366605913,553,235 - 13,609,816 (-)NCBIVero_WHO_p1.0Vero_WHO_p1.0
Ndel1
(Heterocephalus glaber - naked mole-rat)
Naked Mole-Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla_female_1.0 EnsemblNW_00462478611,000,615 - 11,034,689 (+)EnsemblHetGla_female_1.0HetGla_female_1.0 EnsemblhetGla2
HetGla 1.0NW_00462478610,981,963 - 11,039,504 (+)NCBIHetGla_female_1.0HetGla 1.0hetGla2

Variants

.
Variants in Ndel1
328 total Variants
miRNA Target Status

Predicted Target Of
Summary Value
Count of predictions:600
Count of miRNA genes:208
Interacting mature miRNAs:257
Transcripts:ENSRNOT00000005574, ENSRNOT00000065505
Prediction methods:Microtar, Miranda, Rnahybrid, Targetscan
Result types:miRGate_prediction

The detailed report is available here: Full Report CSV TAB Printer

miRNA Target Status data imported from miRGate (http://mirgate.bioinfo.cnio.es/).
For more information about miRGate, see PMID:25858286 or access the full paper here.


QTLs in Region (mRatBN7.2)
The following QTLs overlap with this region.    Full Report CSV TAB Printer Gviewer
RGD IDSymbolNameLODP ValueTraitSub TraitChrStartStopSpecies
70223Bp57Blood pressure QTL 575arterial blood pressure trait (VT:2000000)systolic blood pressure (CMO:0000004)10180676123Rat
631554Bp133Blood pressure QTL 1330.005arterial blood pressure trait (VT:2000000)systolic blood pressure (CMO:0000004)1074336463851208Rat
2298544Neuinf9Neuroinflammation QTL 94.6nervous system integrity trait (VT:0010566)spinal cord complement component 1, q subcomponent, B chain mRNA level (CMO:0002126)10580199062146030Rat
8662860Vetf10Vascular elastic tissue fragility QTL 10artery integrity trait (VT:0010639)number of ruptures of the internal elastic lamina of the abdominal aorta and iliac arteries (CMO:0002562)10615418273453136Rat
61427Cia16Collagen induced arthritis QTL 163.2joint integrity trait (VT:0010548)joint inflammation composite score (CMO:0000919)10635789696121100Rat
2303118Mamtr7Mammary tumor resistance QTL 70.003mammary gland integrity trait (VT:0010552)mammary tumor growth rate (CMO:0000344)109658275104670812Rat
9590310Scort19Serum corticosterone level QTL 196.30.001blood corticosterone amount (VT:0005345)plasma corticosterone level (CMO:0001173)101147401056474010Rat
9590268Scort13Serum corticosterone level QTL 133.260.001blood corticosterone amount (VT:0005345)plasma corticosterone level (CMO:0001173)101147401056474010Rat
9589136Insul27Insulin level QTL 2710.460.001blood insulin amount (VT:0001560)plasma insulin level (CMO:0000342)101147401056474010Rat
2301967Cm73Cardiac mass QTL 734.55heart left ventricle mass (VT:0007031)heart left ventricle weight to body weight ratio (CMO:0000530)101448701189062041Rat
631268Cia21Collagen induced arthritis QTL 213.1joint integrity trait (VT:0010548)joint inflammation composite score (CMO:0000919)1014487011104060283Rat
2316949Gluco60Glucose level QTL 603.7blood glucose amount (VT:0000188)blood glucose level (CMO:0000046)1014487011107057807Rat
1354587Kidm21Kidney mass QTL 213.3kidney mass (VT:0002707)right kidney wet weight (CMO:0000082)101502851360430477Rat
631564Apr3Acute phase response QTL 33.9blood interleukin-6 amount (VT:0008595)plasma interleukin-6 level (CMO:0001927)101527595560275955Rat
6893350Bw99Body weight QTL 990.870.16body mass (VT:0001259)body weight (CMO:0000012)11590666560906665Rat
6893352Bw100Body weight QTL 1000.330.6body mass (VT:0001259)body weight (CMO:0000012)11590666560906665Rat
1598852Anxrr19Anxiety related response QTL 195.07body movement coordination trait (VT:0005424)number of rearing movements in an experimental apparatus (CMO:0001752)101816784163167841Rat
2313055Bw96Body weight QTL 963.60.0001body mass (VT:0001259)body weight (CMO:0000012)101960648364606483Rat
2313087Bmd80Bone mineral density QTL 803.20.0001tibia mineral mass (VT:1000283)total volumetric bone mineral density (CMO:0001728)101960648364606483Rat
1554317Bmd4Bone mineral density QTL 49.40.0001lumbar vertebra mineral mass (VT:0010511)volumetric bone mineral density (CMO:0001553)101981604299406971Rat
1581497Esta1Estrogen-induced thymic atrophy QTL 1thymus mass (VT:0004954)thymus wet weight (CMO:0000855)102132980561345413Rat
724556Pur2Proteinuria QTL 25.5urine protein amount (VT:0005160)urine protein level (CMO:0000591)102242750090627625Rat
61354Pia10Pristane induced arthritis QTL 100.01joint integrity trait (VT:0010548)joint inflammation composite score (CMO:0000919)1023444813104060283Rat
631267Cia20Collagen induced arthritis QTL 203.2joint integrity trait (VT:0010548)joint inflammation composite score (CMO:0000919)1023444813104060283Rat
61325Aia5Adjuvant induced arthritis QTL 50.01joint integrity trait (VT:0010548)joint inflammation composite score (CMO:0000919)1023444813104060283Rat
70224Eae3Experimental allergic encephalomyelitis QTL 34.1nervous system integrity trait (VT:0010566)experimental autoimmune encephalomyelitis incidence/prevalence measurement (CMO:0001046)102652195761345413Rat
1298069Bp168Blood pressure QTL 1685.5blood pressure trait (VT:0000183)systolic blood pressure (CMO:0000004)102652195798003205Rat
631542Bp82Blood pressure QTL 826.8arterial blood pressure trait (VT:2000000)systolic blood pressure (CMO:0000004)102652195798952741Rat
2300171Bmd58Bone mineral density QTL 584.90.0001lumbar vertebra mineral mass (VT:0010511)volumetric bone mineral density (CMO:0001553)102694462871944628Rat
10402859Bp381Blood pressure QTL 3810.002arterial blood pressure trait (VT:2000000)mean arterial blood pressure (CMO:0000009)102760646872606468Rat
2292441Bp308Blood pressure QTL 308arterial blood pressure trait (VT:2000000)mean arterial blood pressure (CMO:0000009)102760646872606468Rat
724527Bp148Blood pressure QTL 1480.0001arterial blood pressure trait (VT:2000000)mean arterial blood pressure (CMO:0000009)102845313673453136Rat
1331762Rf40Renal function QTL 403.873kidney blood vessel physiology trait (VT:0100012)absolute change in renal vascular resistance (CMO:0001900)102929950464155584Rat
1331791Cm31Cardiac mass QTL 313.84606heart mass (VT:0007028)heart wet weight (CMO:0000069)1029299504107211142Rat
631557Bp136Blood pressure QTL 1360.003arterial blood pressure trait (VT:2000000)systolic blood pressure (CMO:0000004)103063205375632053Rat
1576311Pia26Pristane induced arthritis QTL 26joint integrity trait (VT:0010548)joint inflammation composite score (CMO:0000919)103122402675632053Rat
1578779Tcas10Tongue tumor susceptibility QTL 103.12tongue integrity trait (VT:0010553)number of squamous cell tumors of the tongue with diameter greater than 3 mm (CMO:0001950)103129743976297439Rat
1576319Cia29Collagen induced arthritis QTL 29joint integrity trait (VT:0010548)joint inflammation composite score (CMO:0000919)103397392178973921Rat
1358897Stresp6Stress response QTL 64.170.022blood norepinephrine amount (VT:0005663)plasma norepinephrine level (CMO:0001010)103539226764155584Rat
61441Btemp1Thermal response to stress QTL 14body temperature trait (VT:0005535)core body temperature (CMO:0001036)103539245763642539Rat
2317042Aia20Adjuvant induced arthritis QTL 203.38joint integrity trait (VT:0010548)right rear ankle joint diameter (CMO:0002150)103756507982565079Rat
2317043Aia7Adjuvant induced arthritis QTL 73.82joint integrity trait (VT:0010548)left rear ankle joint diameter (CMO:0002149)103756507982565079Rat
1576308Schws1Schwannoma susceptibility QTL 10.0041nervous system integrity trait (VT:0010566)percentage of study population developing trigeminal nerve neurilemmomas during a period of time (CMO:0002017)1040035094102359817Rat
631269Cia22Collagen induced arthritis QTL 228.9joint integrity trait (VT:0010548)joint inflammation composite score (CMO:0000919)1040035094104060283Rat
631270Cia23Collagen induced arthritis QTL 233.9joint integrity trait (VT:0010548)joint inflammation composite score (CMO:0000919)1040035094104060283Rat
631552Vetf2Vascular elastic tissue fragility QTL 24.50.0002aorta elastic tissue integrity trait (VT:0010556)artery internal elastic lamina non-tumorous lesion count (CMO:0001913)104114263386142633Rat
61463Bp12Blood pressure QTL 126.30.0001arterial blood pressure trait (VT:2000000)systolic blood pressure (CMO:0000004)104133325886333258Rat
8552805Bw145Body weight QTL 1452.2body mass (VT:0001259)change in body weight to body weight ratio (CMO:0002216)104194452678307017Rat
1298078Stresp5Stress response QTL 52.990.00025blood corticosterone amount (VT:0005345)plasma corticosterone level (CMO:0001173)1042045676104670812Rat
70188BpQTLcluster1Blood pressure QTL cluster 14.864arterial blood pressure trait (VT:2000000)diastolic blood pressure (CMO:0000005)14232313287323132Rat
70188BpQTLcluster1Blood pressure QTL cluster 14.864arterial blood pressure trait (VT:2000000)systolic blood pressure (CMO:0000004)14232313287323132Rat
70188BpQTLcluster1Blood pressure QTL cluster 14.864arterial blood pressure trait (VT:2000000)mean arterial blood pressure (CMO:0000009)14232313287323132Rat
70188BpQTLcluster1Blood pressure QTL cluster 14.864arterial blood pressure trait (VT:2000000)pulse pressure (CMO:0000292)14232313287323132Rat
70198BpQTLcluster9Blood pressure QTL cluster 92.94arterial blood pressure trait (VT:2000000)mean arterial blood pressure (CMO:0000009)104232313287323132Rat
6893342Cm78Cardiac mass QTL 780.10.88heart mass (VT:0007028)heart weight to body weight ratio (CMO:0000074)104287676679813922Rat
9589030Epfw9Epididymal fat weight QTL 919.240.001epididymal fat pad mass (VT:0010421)epididymal fat pad weight to body weight ratio (CMO:0000658)104444169989441699Rat
7411614Foco18Food consumption QTL 180.001eating behavior trait (VT:0001431)feed conversion ratio (CMO:0001312)104444169989441699Rat
8694173Bw149Body weight QTL 1494.380.001body mass (VT:0001259)body weight gain (CMO:0000420)104444169989441699Rat
2300218Hpcl2Hepatic cholesterol level QTL 2liver cholesterol amount (VT:0010498)liver cholesterol level (CMO:0001597)104502965095600334Rat
631547Bp87Blood pressure QTL 874.5arterial blood pressure trait (VT:2000000)systolic blood pressure (CMO:0000004)104736947092369470Rat
2293705Bmd25Bone mineral density QTL 257.10.0001femur mineral mass (VT:0010011)compact volumetric bone mineral density (CMO:0001730)104944455181709989Rat
7207811Bmd90Bone mineral density QTL 905.2femur size trait (VT:1000369)femoral neck cross-sectional area (CMO:0001697)104944455181709989Rat
2293652Bmd22Bone mineral density QTL 224.90.0001femur mineral mass (VT:0010011)total volumetric bone mineral density (CMO:0001728)104944455181709989Rat
2293669Bmd33Bone mineral density QTL 334.50.0001femur strength trait (VT:0010010)femoral neck polar moment of inertia (CMO:0001670)104944455181709989Rat
2293679Bmd30Bone mineral density QTL 303.50.0001femur mineral mass (VT:0010011)total volumetric bone mineral density (CMO:0001728)104944455181709989Rat
1549846Scl47Serum cholesterol level QTL 473.6blood cholesterol amount (VT:0000180)serum total cholesterol level (CMO:0000363)105057470795574707Rat
70364Bp72Blood pressure QTL 72arterial blood pressure trait (VT:2000000)mean arterial blood pressure (CMO:0000009)105112110096121100Rat
61387Bp1Blood pressure QTL 15.1arterial blood pressure trait (VT:2000000)systolic blood pressure (CMO:0000004)1051770177107211142Rat
61387Bp1Blood pressure QTL 15.1arterial blood pressure trait (VT:2000000)diastolic blood pressure (CMO:0000005)1051770177107211142Rat
1359017Hrtrt21Heart rate QTL 212.4heart pumping trait (VT:2000009)heart rate (CMO:0000002)105177294096772940Rat
631530Tls3T-lymphoma susceptibility QTL 300.0001thymus integrity trait (VT:0010555)percentage of study population developing T-cell lymphomas during a period of time (CMO:0001911)105177461295600334Rat
631535Cm51Cardiac mass QTL 513heart mass (VT:0007028)calculated heart weight (CMO:0000073)105178628291669536Rat
1578762Toxo1Toxoplasma gondii resistance QTL 1brain integrity trait (VT:0010579)percentage of study population displaying Toxoplasma gondii brain cysts at a point in time (CMO:0002028)105220003059378278Rat

Markers in Region
RH133557  
Rat AssemblyChrPosition (strand)SourceJBrowse
mRatBN7.21053,530,414 - 53,530,610 (+)MAPPERmRatBN7.2
Rnor_6.01055,411,982 - 55,412,177NCBIRnor6.0
Rnor_5.01055,153,544 - 55,153,739UniSTSRnor5.0
RGSC_v3.41055,581,344 - 55,581,539UniSTSRGSC3.4
Celera1052,697,518 - 52,697,713UniSTS
Cytogenetic Map10q24UniSTS


Expression


RNA-SEQ Expression
High: > 1000 TPM value   Medium: Between 11 and 1000 TPM
Low: Between 0.5 and 10 TPM   Below Cutoff: < 0.5 TPM

alimentary part of gastrointestinal system circulatory system endocrine system exocrine system hemolymphoid system hepatobiliary system integumental system musculoskeletal system nervous system renal system reproductive system respiratory system appendage
High
Medium 3 43 57 41 19 41 8 11 74 35 41 11 8
Low
Below cutoff

Sequence

Nucleotide Sequences
RefSeq Transcripts NM_133320 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_006246573 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_006246574 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_006246575 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_006246578 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_017596976 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_039085116 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_039085117 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_063268359 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_063268360 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_063268361 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
GenBank Nucleotide AC126877 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AY008298 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  BC070909 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  CH473948 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  JAXUCZ010000010 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles

RefSeq Acc Id: ENSRNOT00000005574   ⟹   ENSRNOP00000005574
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.2 Ensembl1053,530,332 - 53,563,269 (-)Ensembl
Rnor_6.0 Ensembl1055,411,901 - 55,444,722 (-)Ensembl
RefSeq Acc Id: ENSRNOT00000065505   ⟹   ENSRNOP00000062145
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.2 Ensembl1053,530,321 - 53,563,337 (-)Ensembl
Rnor_6.0 Ensembl1055,412,279 - 55,444,861 (-)Ensembl
RefSeq Acc Id: ENSRNOT00000096601   ⟹   ENSRNOP00000085535
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.2 Ensembl1053,532,780 - 53,563,325 (-)Ensembl
RefSeq Acc Id: ENSRNOT00000098446   ⟹   ENSRNOP00000090924
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.2 Ensembl1053,530,321 - 53,570,907 (-)Ensembl
RefSeq Acc Id: ENSRNOT00000111866   ⟹   ENSRNOP00000097143
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.2 Ensembl1053,516,491 - 53,563,253 (-)Ensembl
RefSeq Acc Id: NM_133320   ⟹   NP_579854
RefSeq Status: PROVISIONAL
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr81054,029,186 - 54,062,035 (-)NCBI
mRatBN7.21053,530,321 - 53,563,174 (-)NCBI
Rnor_6.01055,411,888 - 55,444,724 (-)NCBI
Rnor_5.01055,140,094 - 55,198,600 (-)NCBI
RGSC_v3.41055,581,250 - 55,614,926 (-)RGD
Celera1052,697,424 - 52,729,662 (-)RGD
Sequence:
RefSeq Acc Id: XM_006246578   ⟹   XP_006246640
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr81054,029,186 - 54,062,231 (-)NCBI
mRatBN7.21053,530,320 - 53,563,315 (-)NCBI
Rnor_6.01055,411,888 - 55,444,876 (-)NCBI
Rnor_5.01055,140,094 - 55,198,600 (-)NCBI
Sequence:
RefSeq Acc Id: XM_017596976   ⟹   XP_017452465
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr81054,001,435 - 54,062,195 (-)NCBI
mRatBN7.21053,505,628 - 53,563,315 (-)NCBI
Rnor_6.01055,398,919 - 55,436,069 (-)NCBI
Sequence:
RefSeq Acc Id: XM_039085116   ⟹   XP_038941044
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr81054,029,186 - 54,080,909 (-)NCBI
mRatBN7.21053,530,320 - 53,582,025 (-)NCBI
RefSeq Acc Id: XM_039085117   ⟹   XP_038941045
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr81054,029,186 - 54,061,935 (-)NCBI
mRatBN7.21053,530,320 - 53,563,077 (-)NCBI
RefSeq Acc Id: XM_063268359   ⟹   XP_063124429
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr81054,029,186 - 54,062,195 (-)NCBI
RefSeq Acc Id: XM_063268360   ⟹   XP_063124430
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr81054,029,186 - 54,080,903 (-)NCBI
RefSeq Acc Id: XM_063268361   ⟹   XP_063124431
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr81054,029,186 - 54,061,938 (-)NCBI
RefSeq Acc Id: NP_579854   ⟸   NM_133320
- UniProtKB: Q6IRI4 (UniProtKB/Swiss-Prot),   Q78PB6 (UniProtKB/Swiss-Prot),   A6HFL2 (UniProtKB/TrEMBL),   A0A8I6AEF7 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: XP_006246640   ⟸   XM_006246578
- Peptide Label: isoform X3
- UniProtKB: A0A8I6A433 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: XP_017452465   ⟸   XM_017596976
- Peptide Label: isoform X4
- UniProtKB: A0A8I6AR01 (UniProtKB/TrEMBL),   A0A8I6A433 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: ENSRNOP00000062145   ⟸   ENSRNOT00000065505
RefSeq Acc Id: ENSRNOP00000005574   ⟸   ENSRNOT00000005574
RefSeq Acc Id: XP_038941044   ⟸   XM_039085116
- Peptide Label: isoform X2
- UniProtKB: Q78PB6 (UniProtKB/Swiss-Prot),   Q6IRI4 (UniProtKB/Swiss-Prot),   A6HFL2 (UniProtKB/TrEMBL),   A0A8I6AEF7 (UniProtKB/TrEMBL)
RefSeq Acc Id: XP_038941045   ⟸   XM_039085117
- Peptide Label: isoform X2
- UniProtKB: Q78PB6 (UniProtKB/Swiss-Prot),   Q6IRI4 (UniProtKB/Swiss-Prot),   A6HFL2 (UniProtKB/TrEMBL),   A0A8I6AEF7 (UniProtKB/TrEMBL)
RefSeq Acc Id: ENSRNOP00000097143   ⟸   ENSRNOT00000111866
RefSeq Acc Id: ENSRNOP00000090924   ⟸   ENSRNOT00000098446
RefSeq Acc Id: ENSRNOP00000085535   ⟸   ENSRNOT00000096601
RefSeq Acc Id: XP_063124430   ⟸   XM_063268360
- Peptide Label: isoform X3
- UniProtKB: A0A8I6A433 (UniProtKB/TrEMBL)
RefSeq Acc Id: XP_063124429   ⟸   XM_063268359
- Peptide Label: isoform X1
- UniProtKB: A0A8I6A433 (UniProtKB/TrEMBL)
RefSeq Acc Id: XP_063124431   ⟸   XM_063268361
- Peptide Label: isoform X3
- UniProtKB: A0A8I6A433 (UniProtKB/TrEMBL)
Protein Domains
NUDE

Protein Structures
Name Modeler Protein Id AA Range Protein Structure
AF-Q78PB6-F1-model_v2 AlphaFold Q78PB6 1-345 view protein structure

Transcriptome

eQTL   View at Phenogen
WGCNA   View at Phenogen
Tissue/Strain Expression   View at Phenogen

Promoters
RGD ID:13697300
Promoter ID:EPDNEW_R7823
Type:initiation region
Name:Ndel1_1
Description:nudE neurodevelopment protein 1-like 1
SO ACC ID:SO:0000170
Source:EPDNEW (Eukaryotic Promoter Database, http://epd.vital-it.ch/)
Experiment Methods:Single-end sequencing.
Position:
Rat AssemblyChrPosition (strand)Source
Rnor_6.01055,444,807 - 55,444,867EPDNEW

Additional Information

Database Acc Id Source(s)
AGR Gene RGD:621235 AgrOrtholog
BioCyc Gene G2FUF-24624 BioCyc
Ensembl Genes ENSRNOG00000004139 Ensembl, ENTREZGENE, UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
Ensembl Transcript ENSRNOT00000005574.8 UniProtKB/Swiss-Prot
  ENSRNOT00000065505.5 UniProtKB/TrEMBL
  ENSRNOT00000096601.1 UniProtKB/TrEMBL
  ENSRNOT00000098446 ENTREZGENE
  ENSRNOT00000098446.1 UniProtKB/TrEMBL
  ENSRNOT00000111866.1 UniProtKB/TrEMBL
Gene3D-CATH 6.10.250.1080 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
IMAGE_CLONE IMAGE:7103650 IMAGE-MGC_LOAD
InterPro NUDE UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  NUDE_dom UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
KEGG Report rno:170845 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
MGC_CLONE MGC:91511 IMAGE-MGC_LOAD
NCBI Gene 170845 ENTREZGENE
PANTHER PTHR10921 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  PTHR10921:SF0 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
Pfam NUDE_C UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
PhenoGen Ndel1 PhenoGen
RatGTEx ENSRNOG00000004139 RatGTEx
UniProt A0A8I6A433 ENTREZGENE, UniProtKB/TrEMBL
  A0A8I6AEF7 ENTREZGENE, UniProtKB/TrEMBL
  A0A8I6AR01 ENTREZGENE, UniProtKB/TrEMBL
  A0A8L2QW10_RAT UniProtKB/TrEMBL
  A6HFL2 ENTREZGENE, UniProtKB/TrEMBL
  NDEL1_RAT UniProtKB/Swiss-Prot
  Q6IRI4 ENTREZGENE
  Q78PB6 ENTREZGENE
UniProt Secondary Q6IRI4 UniProtKB/Swiss-Prot


Nomenclature History
Date Current Symbol Current Name Previous Symbol Previous Name Description Reference Status
2013-11-22 Ndel1  nudE neurodevelopment protein 1-like 1  Ndel1  nudE nuclear distribution gene E homolog (A. nidulans)-like 1  Nomenclature updated to reflect human and mouse nomenclature 1299863 APPROVED
2011-01-13 Ndel1  nudE nuclear distribution gene E homolog (A. nidulans)-like 1  Ndel1  nuclear distribution gene E-like homolog 1 (A. nidulans)  Nomenclature updated to reflect human and mouse nomenclature 1299863 APPROVED
2008-02-19 Ndel1  nuclear distribution gene E-like homolog 1 (A. nidulans)  Ndel1  nudE nuclear distribution gene E homolog like 1 (A. nidulans)  Nomenclature updated to reflect human and mouse nomenclature 1299863 APPROVED
2004-09-10 Ndel1  nudE nuclear distribution gene E homolog like 1 (A. nidulans)  Nudel  LIS1-interacting protein NUDEL; endooligopeptidase A  Symbol and Name updated 1299863 APPROVED
2002-08-07 Nudel  LIS1-interacting protein NUDEL; endooligopeptidase A      Symbol and Name status set to provisional 70820 PROVISIONAL