NDEL1 (nudE neurodevelopment protein 1 like 1)

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Gene: NDEL1 (nudE neurodevelopment protein 1 like 1) Chlorocebus sabaeus

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Symbol:

NDEL1

Name:

nudE neurodevelopment protein 1 like 1

RGD ID:

18636728

Description:

ENCODES a protein that exhibits oligopeptidase activity (ortholog); protein-containing complex binding (ortholog); INVOLVED IN activation of GTPase activity (ortholog); canonical Wnt signaling pathway (ortholog); cell migration (ortholog); ASSOCIATED WITH juvenile rheumatoid arthritis (ortholog); schizophrenia (ortholog); FOUND IN axon (ortholog); cell body (ortholog); central region of growth cone (ortholog)

Type:

protein-coding

RefSeq Status:

MODEL

Previously known as:

nuclear distribution protein nudE-like 1

RGD Orthologs

Alliance Orthologs

More Info

more info ...

Latest Assembly:

ChlSab1.1 - Green Monkey 1.1 Assembly

Position:

Green Monkey Assembly	Chr	Position (strand)	Source	Genome Browsers
Green Monkey Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
ChlSab1.1	16	7,797,858 - 7,831,211 (+)	NCBI	ChlSab1.1	ChlSab1.1	chlSab2
Vero_WHO_p1.0	NW_023666059	13,553,235 - 13,609,816 (-)	NCBI	Vero_WHO_p1.0	Vero_WHO_p1.0

JBrowse:

View Region in Genome Browser (JBrowse)

Model

Annotation Click to see Annotation Detail View

Disease Annotations Click to see Annotation Detail View

juvenile rheumatoid arthritis (ISO)

schizophrenia (ISO)

Gene Ontology Annotations Click to see Annotation Detail View

Biological Process

activation of GTPase activity (ISO)

canonical Wnt signaling pathway (ISO)

cell migration (IEA,ISO)

central nervous system neuron axonogenesis (IEA,ISO)

centrosome localization (IEA,ISO)

cerebral cortex radially oriented cell migration (IEA)

chromosome segregation (IEA)

establishment of chromosome localization (IEA)

establishment of mitotic spindle orientation (IEA)

inner cell mass cell proliferation (IEA,ISO)

insulin receptor signaling pathway (IEA)

lysosome localization (IEA)

microtubule cytoskeleton organization (IEA,ISO)

microtubule nucleation (IEA)

mitotic centrosome separation (IEA,ISO)

nervous system development (IEA)

neurofilament cytoskeleton organization (IEA,ISO)

neuron migration (IEA,ISO)

neuron projection development (ISO)

neuron projection extension (IEA,ISO)

nuclear membrane disassembly (ISO)

positive regulation of axon extension (ISO)

positive regulation of axon regeneration (ISO)

positive regulation of GTPase activity (ISO)

positive regulation of ruffle assembly (IEA)

radial glia-guided pyramidal neuron migration (IEA,ISO)

regulation of intracellular protein transport (IEA)

regulation of neuron projection development (IEA)

retrograde axonal transport (IEA,ISO)

vesicle transport along microtubule (IEA,ISO)

Cellular Component

axon (IEA,ISO)

axon cytoplasm (IEA)

axon hillock (IEA)

cell body (ISO)

cell leading edge (IEA)

central region of growth cone (ISO)

centrosome (IEA)

chromosome, centromeric region (IEA)

cytoplasm (IEA)

cytoskeleton (IEA)

kinesin complex (IEA,ISO)

kinetochore (IEA)

microtubule (IEA)

microtubule associated complex (IEA)

microtubule organizing center (IEA)

neurofilament cytoskeleton (IEA)

nuclear envelope (ISO)

spindle (IEA)

synaptic vesicle (IEA)

Molecular Function

alpha-tubulin binding (IEA)

beta-tubulin binding (IEA)

identical protein binding (IEA)

microtubule binding (IEA)

oligopeptidase activity (ISO)

protein binding (ISO)

protein-containing complex binding (ISO)

References

Additional References at PubMed

PMID:30032202

Genomics

Comparative Map Data

NDEL1
(Chlorocebus sabaeus - green monkey)

Green Monkey Assembly	Chr	Position (strand)	Source	Genome Browsers
Green Monkey Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
ChlSab1.1	16	7,797,858 - 7,831,211 (+)	NCBI	ChlSab1.1	ChlSab1.1	chlSab2
Vero_WHO_p1.0	NW_023666059	13,553,235 - 13,609,816 (-)	NCBI	Vero_WHO_p1.0	Vero_WHO_p1.0

NDEL1
(Homo sapiens - human)

Human Assembly	Chr	Position (strand)	Source	Genome Browsers
Human Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
GRCh38	17	8,413,131 - 8,474,328 (+)	NCBI	GRCh38	GRCh38	hg38	GRCh38
GRCh38.p14 Ensembl	17	8,413,131 - 8,490,411 (+)	Ensembl	GRCh38		hg38	GRCh38
GRCh37	17	8,339,202 - 8,371,481 (+)	NCBI	GRCh37	GRCh37	hg19	GRCh37
Build 36	17	8,279,904 - 8,312,206 (+)	NCBI	NCBI36	Build 36	hg18	NCBI36
Build 34	17	8,279,903 - 8,312,196	NCBI
Celera	17	8,370,018 - 8,402,309 (+)	NCBI		Celera
Cytogenetic Map	17	p13.1	NCBI
HuRef	17	8,238,370 - 8,270,684 (+)	NCBI		HuRef
CHM1_1	17	8,348,024 - 8,380,341 (+)	NCBI		CHM1_1
T2T-CHM13v2.0	17	8,319,371 - 8,379,912 (+)	NCBI		T2T-CHM13v2.0

Ndel1
(Mus musculus - house mouse)

Mouse Assembly	Chr	Position (strand)	Source	Genome Browsers
Mouse Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
GRCm39	11	68,712,260 - 68,743,961 (-)	NCBI	GRCm39	GRCm39	mm39
GRCm39 Ensembl	11	68,712,260 - 68,762,684 (-)	Ensembl		GRCm39 Ensembl
GRCm38	11	68,821,434 - 68,853,146 (-)	NCBI	GRCm38	GRCm38	mm10	GRCm38
GRCm38.p6 Ensembl	11	68,821,434 - 68,871,858 (-)	Ensembl	GRCm38		mm10	GRCm38
MGSCv37	11	68,634,936 - 68,666,633 (-)	NCBI	GRCm37	MGSCv37	mm9	NCBIm37
MGSCv36	11	68,637,629 - 68,669,257 (-)	NCBI		MGSCv36	mm8
Celera	11	75,766,319 - 75,797,740 (-)	NCBI		Celera
Cytogenetic Map	11	B3	NCBI
cM Map	11	42.09	NCBI

Ndel1
(Rattus norvegicus - Norway rat)

Rat Assembly	Chr	Position (strand)	Source	Genome Browsers
Rat Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
GRCr8	10	54,001,435 - 54,080,909 (-)	NCBI		GRCr8
mRatBN7.2	10	53,505,628 - 53,582,025 (-)	NCBI	mRatBN7.2	mRatBN7.2
mRatBN7.2 Ensembl	10	53,516,491 - 53,570,907 (-)	Ensembl		mRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx	10	58,191,668 - 58,224,366 (-)	NCBI	Rnor_SHR	UTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.0	10	57,680,698 - 57,713,203 (-)	NCBI	Rnor_SHRSP	UTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.0	10	53,189,257 - 53,222,150 (-)	NCBI	Rnor_WKY	UTH_Rnor_WKY_Bbb_1.0
Rnor_6.0	10	55,398,919 - 55,456,654 (-)	NCBI	Rnor6.0	Rnor_6.0	rn6	Rnor6.0
Rnor_6.0 Ensembl	10	55,411,901 - 55,444,861 (-)	Ensembl	Rnor6.0		rn6	Rnor6.0
Rnor_5.0	10	55,140,094 - 55,198,600 (-)	NCBI	Rnor5.0	Rnor_5.0	rn5	Rnor5.0
RGSC_v3.4	10	55,581,250 - 55,614,926 (-)	NCBI	RGSC3.4	RGSC_v3.4	rn4	RGSC3.4
RGSC_v3.1	10	55,594,876 - 55,628,545 (-)	NCBI
Celera	10	52,697,424 - 52,729,662 (-)	NCBI		Celera
Cytogenetic Map	10	q24	NCBI

Ndel1
(Chinchilla lanigera - long-tailed chinchilla)

Chinchilla Assembly	Chr	Position (strand)	Source	Genome Browsers
Chinchilla Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
ChiLan1.0 Ensembl	NW_004955467	8,432,806 - 8,468,155 (-)	Ensembl	ChiLan1.0
ChiLan1.0	NW_004955467	8,432,806 - 8,486,563 (-)	NCBI	ChiLan1.0	ChiLan1.0

NDEL1
(Pan paniscus - bonobo/pygmy chimpanzee)

Bonobo Assembly	Chr	Position (strand)	Source	Genome Browsers
Bonobo Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
NHGRI_mPanPan1-v2	19	65,280,844 - 65,313,183 (-)	NCBI		NHGRI_mPanPan1-v2
NHGRI_mPanPan1	17	70,090,295 - 70,122,627 (-)	NCBI		NHGRI_mPanPan1
Mhudiblu_PPA_v0	17	43,186,255 - 43,218,436 (-)	NCBI	Mhudiblu_PPA_v0	Mhudiblu_PPA_v0	panPan3
PanPan1.1	17	47,918,827 - 47,942,773 (-)	NCBI	panpan1.1	PanPan1.1	panPan2
PanPan1.1 Ensembl	17	47,918,827 - 47,950,749 (-)	Ensembl	panpan1.1		panPan2

NDEL1
(Canis lupus familiaris - dog)

Dog Assembly	Chr	Position (strand)	Source	Genome Browsers
Dog Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
CanFam3.1	5	33,187,614 - 33,244,483 (+)	NCBI	CanFam3.1	CanFam3.1	canFam3	CanFam3.1
CanFam3.1 Ensembl	5	33,204,452 - 33,266,052 (+)	Ensembl	CanFam3.1		canFam3	CanFam3.1
Dog10K_Boxer_Tasha	5	33,323,255 - 33,402,505 (+)	NCBI		Dog10K_Boxer_Tasha
ROS_Cfam_1.0	5	33,290,630 - 33,369,996 (+)	NCBI		ROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl	5	33,307,740 - 33,375,499 (+)	Ensembl		ROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.1	5	33,257,900 - 33,337,132 (+)	NCBI		UMICH_Zoey_3.1
UNSW_CanFamBas_1.0	5	33,213,196 - 33,292,473 (+)	NCBI		UNSW_CanFamBas_1.0
UU_Cfam_GSD_1.0	5	33,393,012 - 33,472,138 (+)	NCBI		UU_Cfam_GSD_1.0

Ndel1
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)

Squirrel Assembly	Chr	Position (strand)	Source	Genome Browsers
Squirrel Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
HiC_Itri_2	NW_024405602	48,182,799 - 48,227,535 (+)	NCBI		HiC_Itri_2
SpeTri2.0 Ensembl	NW_004936595	1,656,956 - 1,689,322 (+)	Ensembl	SpeTri2.0	SpeTri2.0 Ensembl
SpeTri2.0	NW_004936595	1,656,956 - 1,692,775 (+)	NCBI	SpeTri2.0	SpeTri2.0		SpeTri2.0

NDEL1
(Sus scrofa - pig)

Pig Assembly	Chr	Position (strand)	Source	Genome Browsers
Pig Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
Sscrofa11.1 Ensembl	12	53,557,175 - 53,640,457 (+)	Ensembl	Sscrofa11.1		susScr11	Sscrofa11.1
Sscrofa11.1	12	53,553,897 - 53,640,470 (+)	NCBI	Sscrofa11.1	Sscrofa11.1	susScr11	Sscrofa11.1
Sscrofa10.2	12	56,296,922 - 56,336,396 (+)	NCBI	Sscrofa10.2	Sscrofa10.2	susScr3

Ndel1
(Heterocephalus glaber - naked mole-rat)

Naked Mole-Rat Assembly	Chr	Position (strand)	Source	Genome Browsers
Naked Mole-Rat Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
HetGla_female_1.0 Ensembl	NW_004624786	11,000,615 - 11,034,689 (+)	Ensembl	HetGla_female_1.0	HetGla_female_1.0 Ensembl	hetGla2
HetGla 1.0	NW_004624786	10,981,963 - 11,039,504 (+)	NCBI	HetGla_female_1.0	HetGla 1.0	hetGla2

Expression

RNA-SEQ Expression

Click on a value in the shaded box below the category label to view a detailed expression data table for that system.

Sequence

Nucleotide Sequences


RefSeq Transcripts	XM_008010298	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	XM_037987327	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	XM_037987328	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
GenBank Nucleotide	JACDXN010000027	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles

RefSeq Acc Id:

XM_008010298 ⟹ XP_008008489

Type:

CODING

Position:

Green Monkey Assembly	Chr	Position (strand)	Source
ChlSab1.1	16	7,797,858 - 7,831,211 (+)	NCBI
Vero_WHO_p1.0	NW_023666059	13,553,236 - 13,586,542 (-)	NCBI

Sequence:

show sequence

ATGGCCTCGGACACCCAGGCAGTCCCTGACGTGTCGGGGAGGAGCCGGGCGCGGAGGTACGCGG
AGTGGAGCTCGGGGCTGCGGAGGGGAGCTGAGCCGAGCGGCTGGGCGGGCCTGGCCAGGCCANG
CGGAGCGGAGACGTGGGTCAAGCGGCGGCGAACATGCGCTTTTGACACATTGGAGGCTTTCTTG
ATCATGGATGGTGAAGATATACCAGATTTTTCAAGTTTAAAGGAGGAAACTGCTTATTGGAAGG
AACTTTCCTTGAAGTATAAGCAAAGCTTCCAGGAAGCTCGGGATGAGCTAGTTGAATTCCAGGA
AGGAAGCAGAGAATTAGAAGCAGAGTTGGAGGCACAATTAGTACAGGCTGAACAAAGAAATAGA
GACTTGCAGGCTGATAACCAAAGACTGAAATATGAAGTGGAGGCATTAAAGGAGAAGCTAGAGC
ATCAATATGCACAGAGCTATAAGCAGGTCTCAGTGTTAGAAGATGATTTAAGTCAGGCTCGGGC
CATTAAGGAGCAGTTGCATAAGTATGTGAGAGAGCTGGAGCAGGCCAACGACGACCTGGAGCGA
GCCAAAAGGGCAACAATAGTTTCACTGGAAGACTTTGAACAAAGGCTAAATCAGGCCATTGAAC
GAAATGCATTTTTAGAAAGTGAACTTGATGAAAAGGAATCTTTGTTGGTCTCTGTACAGAGGTT
AAAGGATGAAGCAAGAGATTTAAGGCAAGAACTAGCAGTTCGGGAAAGACAACAGGAAGTAACT
AGAAAGTCGGCTCCTAGCTCTCCAACTCTGGACTGTGAAAAGATGGACTCCGCCGTCCAAGCAT
CACTCTCTTTGCCAGCTACCCCTGTTGGCAAAGGAACGGAGAACACTTTTCCATCACCGAAAGC
TATACCAAACGGTTTTGGTACCAGTCCACTAACTCCCTCTGCTAGGATATCAGCACTAAACATC
GTGGGGGATCTCTTACGGAAAGTAGGGGCTTTAGAATCCAAATTAGCAGCTTGCAGGAATTTTG
CAAAGGACCAAGCATCACGAAAATCCTATATTTCAGGGAATGTTAACTGTGGGGTGCTGAATGG
CAATGGCACAAAGTTCTCTCGATCAGGGCATACATCTTTCTTCGACAAAGGGGCAGTAAACGGC
TTTGACCCCGCTCCTCCTCCTCCTGGTCTGGGCTCCTCGCGTCCGTCGTCAGCGCCGGGTATGC
TGCCTCTCAGTGTGTGAGTGCCCAGCCTCCAGGTGGGGCTCCTGCCCTCCTCCAGCAACCCAGG
ACACCCACGCCTCACCCCTCGGTGCCTGGGCCCAGCCCCGTGCCCCTCCGTCTGCCTCCGCACG
GCCGGCAGAGGCCAGGCTGCATGCAGTGGCGGCTGCTGGGCCCTGCCCAGCCCCGGAACTCTGC
GCGATATCAATACTGGCTATTTTCTCTTCTCGCCGTAGTGCCGTTGGTTTCACATGATTGCACT
TTCGTGGGTCACAAGGTGATACATACGTGTATTACTTGGTCACTGGATGCAGAAGTACCCATTC
ATCGCACCTGCCTCATAGCCCCCACTCTGCTGTACGGATAGGATTTAGTTGTGTTTAGGACATT
GCAAATCTTCTAGAAGTTCTCCCCCAAATCAGGTCAATGTGTGCCCTCCTGAGCTCCCACCCAG
GCATCTCCAGTGCTCATGATCATGTGTCCCCCAACTCCGCCCCTCACGGTTTGGGCCTGTTTCT
GGCAGAGAGTCAGGAAGGTTACTGAATTAGGGAACATTTTCTGCACCTTCTGATTTTACTTAAG
CAGCTACCATTCCATGGACTTGCCTCCCAGAGCAGCACAATGCCCGTCTGGGCCCCACGTGGCA
GGAGCCTCTGGGACGGGGCACACACGGGCCGAGCCTCTGTGCTGTCTCCTCCTCCGGGCGCCTC
AGACTCGGGGTGAGGGAGGCGGGCAGCCTCTCGCCAGCCTTCCCGTCCTTCAGTTCAACCACAT
CTTTGGAGCGTTTTTGTTTTCTCTTCCAAGGGCCGTCCCGTTGTGTTCGGAAGGGTGAGTGGCT
GGTTCCAGGGCAGGCTGGTACCAGCTCCGGGGTGGACTGAACAGCGGCGGCTGTCCCTGTGCAT
CCTTTGATTACTCTCATGCTGCATTTACTGTTTACATTTGTTTTATTGTACATAGGTTTGTAAA
CGTTATTGCCTAAGATATTTGTATATAACTTGGGCTTTGTAGCTTTTATTTATTCAGAACTCAT
ATGGCATGTTAATGACTCTGATGGTGTCCTACTCTGGGCAGCTGTATAGGATCATCATGTGGTT
ACAAAAAATACTTCCCCTCAAAAAAAGTCTTTTAATGTGGAAACAATAAATTTCACAGAAAAAA
AAGGA

hide sequence

RefSeq Acc Id:

XM_037987327 ⟹ XP_037843255

Type:

CODING

Position:

Green Monkey Assembly	Chr	Position (strand)	Source
Vero_WHO_p1.0	NW_023666059	13,553,236 - 13,609,816 (-)	NCBI

RefSeq Acc Id:

XM_037987328 ⟹ XP_037843256

Type:

CODING

Position:

Green Monkey Assembly	Chr	Position (strand)	Source
Vero_WHO_p1.0	NW_023666059	13,553,235 - 13,586,542 (-)	NCBI

Protein Sequences


Protein RefSeqs	XP_008008489	(Get FASTA)	NCBI Sequence Viewer
	XP_037843255	(Get FASTA)	NCBI Sequence Viewer
	XP_037843256	(Get FASTA)	NCBI Sequence Viewer
Ensembl Protein	ENSCSAP00000006672.1

RefSeq Acc Id:	XP_008008489 ⟸ XM_008010298
- Peptide Label:	isoform X1
- UniProtKB:	A0A0D9RDI3 (UniProtKB/TrEMBL)

RefSeq Acc Id:	XP_037843256 ⟸ XM_037987328
- Peptide Label:	isoform X2
- UniProtKB:	A0A0D9RDI3 (UniProtKB/TrEMBL)

RefSeq Acc Id:	XP_037843255 ⟸ XM_037987327
- Peptide Label:	isoform X1
- UniProtKB:	A0A0D9RDI3 (UniProtKB/TrEMBL)

Additional Information

External Database Links

Database	Acc Id	Source(s)
Ensembl Genes	ENSCSAG00000010441	UniProtKB/TrEMBL
Ensembl Transcript	ENSCSAT00000008530.1	UniProtKB/TrEMBL
Gene3D-CATH	6.10.250.1080	UniProtKB/TrEMBL
InterPro	NUDE	UniProtKB/TrEMBL
	NUDE_dom	UniProtKB/TrEMBL
NCBI Gene	NDEL1	ENTREZGENE
PANTHER	NUCLEAR DISTRIBUTION PROTEIN NUDE HOMOLOG 1	UniProtKB/TrEMBL
	NUCLEAR DISTRIBUTION PROTEIN NUDE-LIKE 1	UniProtKB/TrEMBL
Pfam	NUDE_C	UniProtKB/TrEMBL
UniProt	A0A0D9RDI3	ENTREZGENE, UniProtKB/TrEMBL

Gene Annotator (Functional Annotation) unavailable	Gene Annotator (Annotation Distribution) unavailable	Variant Visualizer (Genomic Variants) unavailble Variant Visualizer (Genomic Variants) unavailable
Gene Annotator (Functional Annotation)	Gene Annotator (Annotation Distribution)	Variant Visualizer (Genomic Variants)

InterViewer (Protein-Protein Interactions) unavailable	Gviewer (Genome Viewer) unavailable	Variant Visualizer (Damaging Variants) unavailble Variant Visualizer (Damaging Variants) unavailable
InterViewer (Protein-Protein Interactions)	GViewer (Genome Viewer)	Variant Visualizer (Damaging Variants)

Gene Annotator (Annotation Comparison) unavailable	OLGA (Gene List Generator) unavailable
Gene Annotator (Annotation Comparison)	OLGA (Gene List Generator)	Excel (Download)

MOET (Multi-Ontology Enrichement) unavailable	GOLF (Gene-Ortholog Location Finder) unavailable
MOET (Multi-Ontology Enrichement)	GOLF (Gene-Ortholog Location Finder)

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Imported Disease Annotations - CTD